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Arin B. Aurora, … , Hesham A. Sadek, Eric N. Olson
Published February 24, 2014
Citation Information: J Clin Invest. 2014;124(3):1382-1392. https://doi.org/10.1172/JCI72181.
Citation Information: J Clin Invest. 2014;124(3):1382-1392. https://doi.org/10.1172/JCI72181.
Abstract
Myocardial infarction (MI) leads to cardiomyocyte death, which triggers an immune response that clears debris and restores tissue integrity. In the adult heart, the immune system facilitates scar formation, which repairs the damaged myocardium but compromises cardiac function. In neonatal mice, the heart can regenerate fully without scarring following MI; however, this regenerative capacity is lost by P7. The signals that govern neonatal heart regeneration are unknown. By comparing the immune response to MI in mice at P1 and P14, we identified differences in the magnitude and kinetics of monocyte and macrophage responses to injury. Using a cell-depletion model, we determined that heart regeneration and neoangiogenesis following MI depends on neonatal macrophages. Neonates depleted of macrophages were unable to regenerate myocardia and formed fibrotic scars, resulting in reduced cardiac function and angiogenesis. Immunophenotyping and gene expression profiling of cardiac macrophages from regenerating and nonregenerating hearts indicated that regenerative macrophages have a unique polarization phenotype and secrete numerous soluble factors that may facilitate the formation of new myocardium. Our findings suggest that macrophages provide necessary signals to drive angiogenesis and regeneration of the neonatal mouse heart. Modulating inflammation may provide a key therapeutic strategy to support heart regeneration.
Authors
Arin B. Aurora, Enzo R. Porrello, Wei Tan, Ahmed I. Mahmoud, Joseph A. Hill, Rhonda Bassel-Duby, Hesham A. Sadek, Eric N. Olson
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Citations to this article (441)
| Title and authors | Publication | Year |
|---|---|---|
|
Cross-species comparison reveals that Hmga1 reduces H3K27me3 levels to promote cardiomyocyte proliferation and cardiac regeneration
Bouwman M, de Bakker DE, Honkoop H, Giovou AE, Versteeg D, Boender AR, Nguyen PD, Slotboom M, Colquhoun D, Vigil-Garcia M, Kooijman L, Janssen R, Hooijkaas IB, Günthel M, Visser KJ, Klerk M, Zentilin L, Giacca M, Kaslin J, Boink GJ, van Rooij E, Christoffels VM, Bakkers J |
Nature Cardiovascular Research | 2025 |
|
Revitalizing the heart: strategies and tools for cardiomyocyte regeneration post-myocardial infarction
Bois A, Grandela C, Gallant J, Mummery C, Menasché P |
NPJ Regenerative Medicine | 2025 |
|
Early Age Efferocytosis Directs Macrophage Arachidonic Acid Metabolism for Tissue Regeneration
Lantz C, Becker A, DeBerge M, Filipp M, Glinton K, Ananthakrishnan A, Urbanczyk J, Cetlin M, Alzamroon A, Abdel-Latif A, Spite M, Ge ZD, Thorp EB |
Immunity | 2025 |
|
Tissue macrophages: origin, heterogenity, biological functions, diseases and therapeutic targets
Guan F, Wang R, Yi Z, Luo P, Liu W, Xie Y, Liu Z, Xia Z, Zhang H, Cheng Q |
Signal Transduction and Targeted Therapy | 2025 |
|
Quercetin-Loaded Nanoparticle-Modified Decellularized Tissue-Engineered Vascular Graft Regulates Macrophage Polarization and Promotes In Vivo Graft Remodeling
Wang T, He Z, Lu P, Liao S, Cheng S, Wang T, An Y, Cheng Z, Shu C |
International Journal of Nanomedicine | 2025 |
|
Cold and hot fibrosis define clinically distinct cardiac pathologies
Miyara S, Adler M, Umansky KB, Häußler D, Bassat E, Divinsky Y, Elkahal J, Kain D, Lendengolts D, Ramirez Flores RO, Bueno-Levy H, Golani O, Shalit T, Gershovits M, Weizman E, Genzelinakh A, Kimchi DM, Shakked A, Zhang L, Wang J, Baehr A, Petrover Z, Sarig R, Dorn T, Moretti A, Saez-Rodriguez J, Kupatt C, Tanaka EM, Medzhitov R, Krüger A, Mayo A, Alon U, Tzahor E |
Cell Systems | 2025 |
|
Potential immune involvement in cataract: from mechanisms to future scope of therapies
Chen L, Yao K, Fu QL |
International Journal of Ophthalmology | 2025 |
|
Medium from human iPSC-derived primitive macrophages promotes adult cardiomyocyte proliferation and cardiac regeneration
Xiao Y, Zhang H, Liu X, Xu P, Du H, Wang J, Shen J, Li Y, Wang Y, He C, Feng H, Liu J, Zhou Y, Liu S, Gao Z, Zang J, Bi J, Tang TS, Gu Q, Wei T, Wang J, Song M |
Nature Communications | 2025 |
|
Functional tendon regeneration is driven by regulatory T cells and IL-33 signaling
Arvind V, Crosio G, Howell K, Zhang H, Montero A, Huang AH |
Science Advances | 2025 |
|
Border-zone cardiomyocytes and macrophages regulate extracellular matrix remodeling to promote cardiomyocyte protrusion during cardiac regeneration
Constanty F, Wu B, Wei KH, Lin IT, Dallmann J, Guenther S, Lautenschlaeger T, Priya R, Lai SL, Stainier DY, Beisaw A |
Nature Communications | 2025 |
|
Molecular gatekeepers of endogenous adult mammalian cardiomyocyte proliferation.
Koopmans T, van Rooij E |
Nature reviews. Cardiology | 2025 |
|
Functional diversity of cardiac macrophages in health and disease.
Yang S, Penna V, Lavine KJ |
Nature reviews. Cardiology | 2025 |
|
Cell cycle arrest of cardiomyocytes in the context of cardiac regeneration
Xu Q, Chen X, Zhao C, Liu Y, Wang J, Ao X, Ding W |
Frontiers in Cardiovascular Medicine | 2025 |
|
Single-cell multiomic analysis identifies macrophage subpopulations in promoting heart regeneration
Mingzhu Fu, Shengtao Jia, Longhui Xu, Xin Li, Yufang Lv, Yulong Zhong, Shanshan Ai |
Journal of Clinical Investigation | 2024 |
|
Microbiota affects mitochondria and immune cell infiltrations via alternative polyadenylation during postnatal heart development
Liu X, Shao Y, Han L, Zhu Y, Tu J, Ma J, Zhang R, Yang Z, Chen J |
Frontiers in Cell and Developmental Biology | 2024 |
|
The Role of Immune Cells Driving Electropathology and Atrial Fibrillation
Huang M, Huiskes FG, de Groot NM, Brundel BJ |
Cells | 2024 |
|
Tissue resident macrophages specifically express Lactotransferrin and Vegfc during ear pinna regeneration in spiny mice
Simkin J, Aloysius A, Adam M, Safaee F, Donahue RR, Biswas S, Lakhani Z, Gensel JC, Thybert D, Potter S, Seifert AW |
Developmental Cell | 2024 |
|
Nicorandil-Pretreated Mesenchymal Stem Cell-Derived Exosomes Facilitate Cardiac Repair After Myocardial Infarction via Promoting Macrophage M2 Polarization by Targeting miR-125a-5p/TRAF6/IRF5 Signaling Pathway.
Gong ZT, Xiong YY, Ning Y, Tang RJ, Xu JY, Jiang WY, Li XS, Zhang LL, Chen C, Pan Q, Hu MJ, Xu J, Yang YJ |
International Journal of Nanomedicine | 2024 |
|
Neutrophils facilitate the epicardial regenerative response after zebrafish heart injury
Peterson EA, Sun J, Chen X, Wang J |
Developmental Biology | 2024 |
|
Cardiac fibrogenesis: an immuno-metabolic perspective
Hoque MM, Gbadegoye JO, Hassan FO, Raafat A, Lebeche D |
Frontiers in physiology | 2024 |
|
Cardiac resident macrophages: Spatiotemporal distribution, development, physiological functions, and their translational potential on cardiac diseases.
Jin J, Wang Y, Liu Y, Chakrabarti S, Su Z |
Acta pharmaceutica Sinica. B | 2024 |
|
Regeneration in Mice of Injured Skin, Heart, and Spinal Cord by α-Gal Nanoparticles Recapitulates Regeneration in Amphibians
Galili U, Li J, Schaer GL |
Nanomaterials | 2024 |
|
Antigen presentation plays positive roles in the regenerative response to cardiac injury in zebrafish.
Cardeira-da-Silva J, Wang Q, Sagvekar P, Mintcheva J, Latting S, Günther S, Ramadass R, Yekelchyk M, Preussner J, Looso M, Junker JP, Stainier DYR |
Nature Communications | 2024 |
|
Targeting cardiomyocyte cell cycle regulation in heart failure.
Zhu C, Yuan T, Krishnan J |
Basic Research in Cardiology | 2024 |
|
Structural, angiogenic, and immune responses influencing myocardial regeneration: a glimpse into the crucible
Baccouche BM, Elde S, Wang H, Woo YJ |
npj Regenerative Medicine | 2024 |
|
Loss of developmentally derived Irf8+ macrophages promotes hyperinnervation and arrhythmia in the adult zebrafish heart
Paquette SE, Oduor CI, Gaulke A, Stefan S, Bronk P, Dafonseca V, Barulin N, Lee C, Carley R, Morrison AR, Choi BR, Bailey JA, Plavicki JS |
2024 | |
|
Targeting Interactions between Fibroblasts and Macrophages to Treat Cardiac Fibrosis.
Yang B, Qiao Y, Yan D, Meng Q |
Cells | 2024 |
|
The PD-1–PD-L1 pathway maintains an immunosuppressive environment essential for neonatal heart regeneration
Vargas Aguilar S, Cui M, Tan W, Sanchez-Ortiz E, Bassel-Duby R, Liu N, Olson EN |
2024 | |
|
Macrophages modulate fibrosis during newt lens regeneration.
Tsissios G, Sallese A, Perez-Estrada JR, Tangeman JA, Chen W, Smucker B, Ratvasky SC, Grajales-Esquivel E, Martinez A, Visser KJ, Joven Araus A, Wang H, Simon A, Yun MH, Del Rio-Tsonis K |
Stem Cell Research & Therapy | 2024 |
|
ptx3a(+) fibroblast/epicardial cells provide a transient macrophage niche to promote heart regeneration.
Sun J, Peterson EA, Chen X, Wang J |
Cell Reports | 2024 |
|
Endothelial progenitor cell-derived extracellular vesicles: the world of potential prospects for the treatment of cardiovascular diseases
Chen DX, Lu CH, Na N, Yin RX, Huang F |
Cell & Bioscience | 2024 |
|
Single-nucleus transcriptomics reveal cardiac cell type-specific diversification in metabolic disease transgenic pigs
Miao J, Zhang K, Yang Y, Xu S, Du J, Wu T, Tao C, Wang Y, Yang S |
iScience | 2024 |
|
Infliximab Limits Injury in Myocardial Infarction
Livia C, Inglis S, Crespo\u2010Diaz R, Rizzo S, Mahlberg R, Bagwell M, Hillestad M, Yamada S, Meenakshi Siddharthan DV, Singh RD, Li X, Arrell DK, Stalboerger P, Witt T, El Sabbagh A, Rihal M, Rihal C, Terzic A, Bartunek J, Behfar A |
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease | 2024 |
|
A correctable immune niche for epithelial stem-cell reprogramming and post-viral lung diseases
Kangyun Wu, Yong Zhang, Huiqing Yin-DeClue, Kelly Na Sun, Dailing Mao, Kuangying Yang, Stephen Austin, Erika Crouch, Steven L Brody, Derek E. Byers, Christy Hoffmann, Michael Hughes, Michael J. Holtzman |
Journal of Clinical Investigation | 2024 |
|
Effects and mechanisms of the myocardial microenvironment on cardiomyocyte proliferation and regeneration
Zheng K, Hao Y, Xia C, Cheng S, Yu J, Chen Z, Li Y, Niu Y, Ran S, Wang S, Ye W, Luo Z, Li X, Zhao J, Li R, Zong J, Zhang H, Lai L, Huang P, Zhou C, Xia J, Zhang X, Wu J |
Frontiers in Cell and Developmental Biology | 2024 |
|
Anti-Ferroptotic Treatment Deteriorates Myocardial Infarction by Inhibiting Angiogenesis and Altering Immune Response.
Stairley RA, Trouten AM, Li S, Roddy PL, DeLeon-Pennell KY, Lee KH, Sucov HM, Liu C, Tao G |
Antioxidants (Basel, Switzerland) | 2024 |
|
Mechanically induced M2 macrophages are involved in bone remodeling of the midpalatal suture during palatal expansion
Li L, Zhai M, Cheng C, Cui S, Wang J, Zhang Z, Liu J, Wei F |
Progress in Orthodontics | 2024 |
|
Primitive macrophages enable long-term vascularization of human heart-onchip platforms
Landau S, Zhao Y, Hamidzada H, Kent G, Okhovatian S, Lu RX, Liu C, Wagner KT, Cheung K, Shawky SA, Vosoughi D, Beroncal EL, Fernandes I, Cummins CL, Andreazza AC, Keller GM, Epelman S, Radisic M |
Cell Stem Cell | 2024 |
|
Primitive macrophages induce sarcomeric maturation and functional enhancement of developing human cardiac microtissues via efferocytic pathways
Hamidzada H, Pascual-Gil S, Wu Q, Kent GM, Massé S, Kantores C, Kuzmanov U, Gomez-Garcia MJ, Rafatian N, Gorman RA, Wauchop M, Chen W, Landau S, Subha T, Atkins MH, Zhao Y, Beroncal E, Fernandes I, Nanthakumar J, Vohra S, Wang EY, Sadikov TV, Razani B, McGaha TL, Andreazza AC, Gramolini A, Backx PH, Nanthakumar K, Laflamme MA, Keller G, Radisic M, Epelman S |
Nature cardiovascular research | 2024 |
|
Myocardial Recovery versus Myocardial Regeneration: Mechanisms and Therapeutic Modulation
Cooke JP, Youker KA, Lai L |
Methodist DeBakey Cardiovascular Journal | 2024 |
|
Intramyocardial immunomodulation with human CD16+ monocytes to treat myocardial infarction in pig: a blind randomized preclinical trial
Ascione R, Bruno VD, Johnson T, Sammut E, Bond A, Lopez-Baz D, Deutsch J, Bailey M, Chiribiri A, Patel A, Baker A, Modarai B |
Frontiers in Cardiovascular Medicine | 2024 |
|
Failure to Resolve Inflammation Contributes to Juvenile-Onset Cardiomyopathy in a Mouse Model of Duchenne Muscular Dystrophy
Novak JS, Lischin A, Uapinyoying P, Hindupur R, Jae Moon Y, Bhattacharya S, Tiufekchiev S, Barone V, Mázala DA, Gamu IH, Walters G, Panchapakesan K, Jaiswal JK |
bioRxiv | 2024 |
|
At the heart of inflammation: Unravelling cardiac resident macrophage biology
Liao Y, Zhu L |
Journal of Cellular and Molecular Medicine | 2024 |
|
Global IL4Rα blockade exacerbates heart failure after an ischemic event in mice and humans
Alvarez-Argote S, Almeida VA, Knas MC, Buday SL, Patterson M, O\u2019Meara CC |
American Journal of Physiology - Heart and Circulatory Physiology | 2024 |
|
PD-1-PD-L1 immunomodulatory pathway regulates cardiac regeneration.
Qin J, Huang GN, Moslehi J |
Nature cardiovascular research | 2024 |
|
Cellular crosstalk to regenerate the injured heart.
Riley PR |
Nature cardiovascular research | 2024 |
|
Hallmarks of Regeneration
Poss KD, Tanaka EM |
Cell stem cell | 2024 |
|
Regenerative potential of mouse neonatal intervertebral disc depends on collagen crosslink density
D\u2019Erminio DN, Adelzadeh KA, Rosenberg AM, Wiener RJ, Torre OM, Ferreri ED, Nasser P, Costa KD, Han WM, Huang AH, Iatridis JC |
iScience | 2024 |
|
Cardiac Development at a Single-Cell Resolution.
Wei N, Lee C, Duan L, Galdos FX, Samad T, Raissadati A, Goodyer WR, Wu SM |
Advances in experimental medicine and biology | 2024 |
|
Cardiac Metabolism.
Martin-Puig S, Menendez-Montes I |
Advances in experimental medicine and biology | 2024 |
|
The Role of Retinoic-Acid-Related Orphan Receptor (RORs) in Cellular Homeostasis
Nematisouldaragh D, Kirshenbaum E, Uzonna M, Kirshenbaum L, Rabinovich-Nikitin I |
International Journal of Molecular Sciences | 2024 |
|
The Macrophage–Fibroblast Dipole in the Context of Cardiac Repair and Fibrosis
Psarras S |
Biomolecules | 2024 |
|
The Role of Cardiac Macrophages in Inflammation and Fibrosis after Myocardial Ischemia-Reperfusion
Jin K, Ma Z, Wang X, Gong C, Sheng J, Chen J, Shen S |
Reviews in Cardiovascular Medicine | 2024 |
|
Heme catabolism and heme oxygenase-1-expressing myeloid cells in pathophysiology
Consonni FM, Incerti M, Bertolotti M, Ballerini G, Garlatti V, Sica A |
Frontiers in Immunology | 2024 |
|
TIMD4hiMHCⅡhi Macrophages Preserve Heart Function Through Retnla
Zhang D, Wang X, Zhu L, Chen Y, Yang C, Zhong Z, Kong X, Nan J, Wang C, Hu H, Chen J, Shi P, Hu X, Zhu W, Wang J |
JACC: Basic to Translational Science | 2024 |
|
Cardiomyocyte proliferation: Advances and insights in macrophage-targeted therapy for myocardial injury
Wang T, Wang X, Ren W, Sun Z, Zhang Y, Wu N, Diao H |
Genes & Diseases | 2024 |
|
Macrophage regulation in vascularization upon regeneration and repair of tissue injury and engineered organ transplantation
Li W, Xu Z, Zou B, Yang D, Lu Y, Zhang X, Zhang C, Li Y, Zhu C |
Fundamental Research | 2024 |
|
Malat1 deficiency prevents neonatal heart regeneration by inducing cardiomyocyte binucleation
Galip S Aslan, Nicolas Jaé, Yosif Manavski, Youssef Fouani, Mariana Shumliakivska, Lisa Kettenhausen, Luisa Kirchhof, Stefan Günther, Ariane Fischer, Guillermo Luxán, Stefanie Dimmeler |
JCI Insight | 2023 |
|
Macrophages and Intervertebral Disc Degeneration.
Koroth J, Buko EO, Abbott R, Johnson CP, Ogle BM, Stone LS, Ellingson AM, Bradley EW |
International journal of molecular sciences | 2023 |
|
Murine neonatal cardiac B cells promote cardiomyocyte proliferation and heart regeneration
Tan Y, Duan X, Wang B, Liu X, Zhan Z |
npj Regenerative Medicine | 2023 |
|
Macrophage: Key player in the pathogenesis of autoimmune diseases
Yang S, Zhao M, Jia S |
Frontiers in immunology | 2023 |
|
Neonatal Plasma Exosomes Contribute to Endothelial Cell-Mediated Angiogenesis and Cardiac Repair after Acute Myocardial Infarction
Li X, Lian Y, Wu Y, Ye Z, Feng J, Zhao Y, Guo X, Kang J |
International journal of molecular sciences | 2023 |
|
The role of macrophage subsets in and around the heart in modulating cardiac homeostasis and pathophysiology
Isidoro CA, Deniset JF |
Frontiers in immunology | 2023 |
|
Macrophages and Bone Remodeling
Weivoda MM, Bradley EW |
Journal of Bone and Mineral Research | 2023 |
|
The multifaceted nature of endogenous cardiac regeneration
Rolland L, Jopling C |
Frontiers in Cardiovascular Medicine | 2023 |
|
Myocardial Immune Cells: The Basis of Cardiac Immunology.
Cohen CD, Rousseau ST, Bermea KC, Bhalodia A, Lovell JP, Zita MD, Čiháková D, Adamo L |
Journal of immunology (Baltimore, Md. : 1950) | 2023 |
|
Fibroblast and Immune Cell Cross-Talk in Cardiac Fibrosis.
Hara A, Tallquist MD |
Current Cardiology Reports | 2023 |
|
Emerging roles of macrophages in heart failure and associated treatment approaches
Xie L, Chen J, Wang Y, Jin C, Xie Y, Ma H, Xiang M |
Therapeutic Advances in Chronic Disease | 2023 |
|
Macrophages in cardiac remodelling after myocardial infarction.
Yap J, Irei J, Lozano-Gerona J, Vanapruks S, Bishop T, Boisvert WA |
Nature reviews. Cardiology | 2023 |
|
New Approaches in Heart Research: Prevention Instead of Cardiomyoplasty?
Gaebel R, Lang C, Vasudevan P, Lührs L, de Carvalho KA, Abdelwahid E, David R |
International journal of molecular sciences | 2023 |
|
Interleukin 13 promotes functional recovery after myocardial infarction via direct signaling to macrophages
Santiago Alvarez-Argote, Samantha Paddock, Michael Flinn, Caelan Moreno, Makenna Knas, Victor Alencar-Almeida, Sydney Buday, Michaela Patterson, Yi-Guang Chen, Chien-Wei Lin, Caitlin O'Meara |
JCI Insight | 2023 |
|
The Role of Innate Immune Cells in Cardiac Injury and Repair: A Metabolic Perspective.
Banerjee D, Tian R, Cai S |
Current Cardiology Reports | 2023 |
|
Distinct mononuclear diploid cardiac subpopulation with minimal cell-cell communications persists in embryonic and adult mammalian heart.
Zhu M, Liang H, Zhang Z, Jiang H, Pu J, Hang X, Zhou Q, Xiang J, He X |
Frontiers of Medicine | 2023 |
|
Physiology and diseases of tissue-resident macrophages.
Lazarov T, Juarez-Carreño S, Cox N, Geissmann F |
Nature | 2023 |
|
Macrophages modulate fibrosis during newt lens regeneration
Tsissios G, Sallese A, Perez-Estrada JR, Tangeman JA, Chen W, Smucker B, Ratvasky SC, Grajales-Esquivel E, Martinez A, Visser KJ, Araus AJ, Wang H, Simon A, Yun MH, Rio-Tsonis KD |
2023 | |
|
Polarizing Macrophage Functional Phenotype to Foster Cardiac Regeneration
Molinaro C, Scalise M, Leo I, Salerno L, Sabatino J, Salerno N, De Rosa S, Torella D, Cianflone E, Marino F |
International journal of molecular sciences | 2023 |
|
Dedifferentiation and Proliferation of Artery Endothelial Cells Drive Coronary Collateral Development in Mice
Arolkar G, Kumar SK, Wang H, Gonzalez KM, Kumar S, Bishnoi B, Rios Coronado PE, Woo YJ, Red-Horse K, Das S |
Arteriosclerosis, thrombosis, and vascular biology | 2023 |
|
Recurrent Myocardial Injury Leads to Disease Tolerance in a Murine Model of Stress-Induced Cardiomyopathy
Tiwary SK, Hayashi T, Kovacs A, Mann DL |
JACC: Basic to Translational Science | 2023 |
|
Comparative single-cell profiling reveals distinct cardiac resident macrophages essential for zebrafish heart regeneration.
Wei KH, Lin IT, Chowdhury K, Lim KL, Liu KT, Ko TM, Chang YM, Yang KC, Lai SB |
eLife | 2023 |
|
Communications between macrophages and cardiomyocytes.
Yang P, Chen Z, Huang W, Zhang J, Zou L, Wang H |
Cell communication and signaling : CCS | 2023 |
|
Animal models to study cardiac regeneration.
Weinberger M, Riley PR |
Nature reviews. Cardiology | 2023 |
|
Stem cell-based therapies for heart failure management: a narrative review of current evidence and future perspectives.
Olatunji G, Kokori E, Yusuf I, Ayanleke E, Damilare O, Afolabi S, Adetunji B, Mohammed S, Akinmoju O, Aboderin G, Aderinto N |
Heart Failure Reviews | 2023 |
|
Suppression of myeloid YAP antagonizes adverse cardiac remodeling during pressure overload stress
Francisco J, Guan J, Zhang Y, Nakada Y, Mareedu S, Sung E, Hu CM, Oka S, Zhai P, Sadoshima J, Del Re DP |
Journal of Molecular and Cellular Cardiology | 2023 |
|
Comparative Analysis of Heart Regeneration: Searching for the Key to Heal the Heart—Part II: Molecular Mechanisms of Cardiac Regeneration
Castillo-Casas JM, Caño-Carrillo S, Sánchez-Fernández C, Franco D, Lozano-Velasco E |
Journal of Cardiovascular Development and Disease | 2023 |
|
Microglial Depletion After Brain Injury Prolongs Inflammation and Impairs Brain Repair, Adult Neurogenesis and Pro-Regenerative Signaling
Kanagaraj P, Chen JY, Skaggs K, Qadeer Y, Connors M, Cutler N, Richmond J, Kommidi V, Poles A, Affrunti D, Powell C, Goldman D, Parent JM |
Glia | 2023 |
|
New treatment methods for myocardial infarction
Sun B, Wang L, Guo W, Chen S, Ma Y, Wang D |
Frontiers in Cardiovascular Medicine | 2023 |
|
Macrophage-driven cardiac inflammation and healing: insights from homeostasis and myocardial infarction
Zuo W, Sun R, Ji Z, Ma G |
Cellular & Molecular Biology Letters | 2023 |
|
The role of periostin in cardiac fibrosis.
Qiao B, Liu X, Wang B, Wei S |
Heart Failure Reviews | 2023 |
|
Salvianolic acid B promotes angiogenesis and inhibits cardiomyocyte apoptosis by regulating autophagy in myocardial ischemia
Chen Q, Xu Q, Zhu H, Wang J, Sun N, Bian H, Li Y, Lin C |
Chinese medicine | 2023 |
|
Endothelial cells adopt a pro-reparative immune responsive signature during cardiac injury
Long H, Steimle JD, Grisanti Canozo FJ, Kim JH, Li X, Morikawa Y, Park M, Turaga D, Adachi I, Wythe JD, Samee MA, Martin JF |
Life science alliance | 2023 |
|
Unlocking Cardiomyocyte Renewal Potential for Myocardial Regeneration
Mehdipour M, Park S, Huang GN |
Journal of Molecular and Cellular Cardiology | 2023 |
|
Chemokine CCL2 promotes cardiac regeneration and repair in myocardial infarction mice via activation of the JNK/STAT3 axis.
Wang W, Chen XK, Zhou L, Wang F, He YJ, Lu BJ, Hu ZG, Li ZX, Xia XW, Wang WE, Zeng CY, Li LP |
Acta Pharmacologica Sinica | 2023 |
|
Macrophages modulate fibrosis during newt lens regeneration.
Tsissios G, Sallese A, Perez-Estrada JR, Tangeman JA, Chen W, Smucker B, Ratvasky SC, Grajales-Esquive EL, Martinez A, Visser KJ, Araus AJ, Wang H, Simon A, Yun MH, Rio-Tsonis KD |
Research square | 2023 |
|
Perish in the Attempt: Regulated Cell Death in Regenerative and Nonregenerative Tissue.
Li S, Tao G |
Antioxidants & Redox Signaling | 2023 |
|
The role of cardiac resident macrophage in cardiac aging
Li J, Xin Y, Wang Z, Li J, Li W, Li H |
Aging Cell | 2023 |
|
Identification of diagnostic immune-related gene biomarkers for predicting heart failure after acute myocardial infarction
Hu Y, Chen X, Mei X, Luo Z, Wu H, Zhang H, Zeng Q, Ren H, Xu D |
Open Medicine | 2023 |
|
AP-1 signaling modulates cardiac fibroblast stress responses.
Whitehead AJ, Atcha H, Hocker JD, Ren B, Engler AJ |
Journal of cell science | 2023 |
|
Two decades of heart regeneration research: cardiomyocyte proliferation and beyond
Huang H, Huang GN, Payumo AY |
2023 | |
|
Regenerative loss in the animal kingdom as viewed from the mouse digit tip and heart
Tan FH, Bronner ME |
Developmental Biology | 2023 |
|
Cardiac Macrophage Metabolism in Health and Disease
Kopecky BJ, Lavine KJ |
Trends in endocrinology and metabolism: TEM | 2023 |
|
Type 2 innate immunity drives distinct neonatal immune profile conducive for heart regeneration
F Chen, J Tse, L Jin, C Chook, F Leung, G Tse, C Woo, A Xu, A Chawla, X Tian, T Chan, W Wong |
Theranostics | 2022 |
|
Coupled myovascular expansion directs cardiac growth and regeneration
Paige DeBenedittis, Anish Karpurapu, Albert Henry, Michael Thomas, Timothy J. McCord, Kyla Brezitski, Anil Prasad, Yoshihiko Kobayashi, Svati Shah, Christopher Kontos, Purushothama Tata, R. Lumbers, Ravi Karra |
Development (Cambridge, England) | 2022 |
|
Different Roles of Resident and Non-resident Macrophages in Cardiac Fibrosis
S Hu, M Yang, S Huang, S Zhong, Q Zhang, H Ding, X Xiong, Z Hu, Y Yang |
Frontiers in Cardiovascular Medicine | 2022 |
|
Accelerated Growth, Differentiation, and Ploidy with Reduced Proliferation of Right Ventricular Cardiomyocytes in Children with Congenital Heart Defect Tetralogy of Fallot
T Sukhacheva, R Serov, N Nizyaeva, A Burov, S Pavlovich, Y Podurovskaya, M Samsonova, A Chernyaev, A Shchegolev, A Kim, L Bockeria, G Sukhikh |
Cells | 2022 |
|
Aging Activates the Immune System and Alters the Regenerative Capacity in the Zebrafish Heart
H Reuter, B Perner, F Wahl, L Rohde, P Koch, M Groth, K Buder, C Englert |
Cells | 2022 |
|
Leukocyte-Mediated Cardiac Repair after Myocardial Infarction in Non-Regenerative vs. Regenerative Systems
E Peterson, J Sun, J Wang |
Journal of Cardiovascular Development and Disease | 2022 |
|
Measuring cardiomyocyte cell-cycle activity and proliferation in the age of heart regeneration
J Auchampach, L Han, G Huang, B Kühn, J Lough, C OMeara, A Payumo, N Rosenthal, H Sucov, K Yutzey, M Patterson |
American journal of physiology. Heart and circulatory physiology | 2022 |
|
Fibrin, Bone Marrow Cells and Macrophages Interactively Modulate Cardiomyoblast Fate
I Borrego, A Frobert, G Ajalbert, J Valentin, C Kaltenrieder, B Fellay, M Stumpe, S Cook, J Dengjel, M Giraud |
Biomedicines | 2022 |
|
Signaling cascades in the failing heart and emerging therapeutic strategies
X He, T Du, T Long, X Liao, Y Dong, Z Huang |
Signal Transduction and Targeted Therapy | 2022 |
|
VEGF Signaling: Methods and Protocols
L Fiedler, C Pellet-Many |
2022 | |
|
A cardioimmunologist’s toolkit: genetic tools to dissect immune cells in cardiac disease
A Wong, H Hamidzada, S Epelman |
Nature Reviews Cardiology | 2022 |
|
Neonatal injury models: integral tools to decipher the molecular basis of cardiac regeneration
A Costa, S Cushman, B Haubner, A Derda, T Thum, C Bär |
Basic Research in Cardiology | 2022 |
|
Structural and Functional Support by Left Atrial Appendage Transplant to the Left Ventricle after a Myocardial Infarction
J Leinonen, P Leinikka, M Tarkia, M Lampinen, A Emanuelov, R Beeri, E Kankuri, E Mervaala |
International journal of molecular sciences | 2022 |
|
Lineage tracing clarifies the cellular origin of tissue-resident macrophages in the developing heart
K Liu, H Jin, M Tang, S Zhang, X Tian, M Zhang, X Han, X Liu, J Tang, W Pu, Y Li, L He, Z Yang, K Lui, B Zhou |
The Journal of Cell Biology | 2022 |
|
LRP5 regulates cardiomyocyte proliferation and neonatal heart regeneration by the AKT/P21 pathway
H Zhou, F Zhang, Y Wu, H Liu, R Duan, Y Liu, Y Wang, X He, Y Zhang, X Ma, Y Guan, Y Liu, D Liang, L Zhou, Y Chen |
Journal of Cellular and Molecular Medicine | 2022 |
|
The Dynamic Role of Cardiac Macrophages in Aging and Disease
J Jimenez, K Lavine |
Current Cardiology Reports | 2022 |
|
Mosaic loss of chromosome Y in peripheral blood cells is associated with age-related macular degeneration in men
Q Duan, Y Gao, , S Wang, M Xu, O Jones, X Xu |
Cell & Bioscience | 2022 |
|
Investigating the Paracrine Role of Perinatal Derivatives: Human Amniotic Fluid Stem Cell-Extracellular Vesicles Show Promising Transient Potential for Cardiomyocyte Renewal
Costa A, Balbi C, Garbati P, Palamà ME, Reverberi D, De Palma A, Rossi R, Paladini D, Coviello D, De Biasio P, Ceresa D, Malatesta P, Mauri P, Quarto R, Gentili C, Barile L, Bollini S |
Frontiers in Bioengineering and Biotechnology | 2022 |
|
Exploring the Immune Infiltration Landscape and M2 Macrophage-Related Biomarkers of Proliferative Diabetic Retinopathy
Meng Z, Chen Y, Wu W, Yan B, Meng Y, Liang Y, Yao X, Luo J |
Frontiers in Endocrinology | 2022 |
|
Immune cells in cardiac repair and regeneration
Simões FC, Riley PR |
Development (Cambridge, England) | 2022 |
|
Akkermansia muciniphila prevents cold-related atrial fibrillation in rats by modulation of TMAO induced cardiac pyroptosis
Luo Y, Zhang Y, Han X, Yuan Y, Zhou Y, Gao Y, Yu H, Zhang J, Shi Y, Duan Y, Zhao X, Yan S, Hao H, Dai C, Zhao S, Shi J, Li W, Zhang S, Xu W, Fang N, Gong Y, Li Y |
EBioMedicine | 2022 |
|
Angiogenesis: A critical determinant for cardiac regeneration
Singh S, Prakash S, Gupta SK |
2022 | |
|
Adult T-cells impair neonatal cardiac regeneration
Dolejsi T, Delgobo M, Schuetz T, Tortola L, Heinze KG, Hofmann U, Frantz S, Bauer A, Ruschitzka F, Penninger JM, Campos Ramos G, Haubner BJ |
European Heart Journal | 2022 |
|
Metabolic Regulation of Cardiac Regeneration
Duan X, Liu X, Zhan Z |
Frontiers in Cardiovascular Medicine | 2022 |
|
Turning back the clock: A concise viewpoint of cardiomyocyte cell cycle activation for myocardial regeneration and repair.
Zhu W, Sun J, Bishop SP, Sadek H, Zhang J |
Journal of Molecular and Cellular Cardiology | 2022 |
|
Mammalian organ regeneration in spiny mice.
Okamura DM, Nguyen ED, Collins SJ, Yoon K, Gere JB, Weiser-Evans MCM, Beier DR, Majesky MW |
Journal of Muscle Research and Cell Motility | 2022 |
|
An anti-inflammatory activation sequence governs macrophage transcriptional dynamics during tissue injury in zebrafish
Denans N, Tran NT, Swall ME, Diaz DC, Blanck J, Piotrowski T |
Nature Communications | 2022 |
|
Macrophages play a key role in tissue repair and regeneration
Yu Y, Yue Z, Xu M, Zhang M, Shen X, Ma Z, Li J, Xie X |
PeerJ | 2022 |
|
Macrophage, a potential targeted therapeutic immune cell for cardiomyopathy
Chen G, Jiang H, Yao Y, Tao Z, Chen W, Huang F, Chen X |
Frontiers in Cell and Developmental Biology | 2022 |
|
α-Gal Nanoparticles Mediated Homing of Endogenous Stem Cells for Repair and Regeneration of External and Internal Injuries by Localized Complement Activation and Macrophage Recruitment
Galili U, Goldufsky JW, Schaer GL |
International journal of molecular sciences | 2022 |
|
Macrophages in myocardial infarction.
Kubota A, Frangogiannis NG |
American journal of physiology. Cell physiology | 2022 |
|
Osteopontin promotes infarct repair.
Rotem I, Konfino T, Caller T, Schary Y, Shaihov-Teper O, Palevski D, Lewis N, Lendengolts D, Naftali-Shani N, Leor J |
Basic Research in Cardiology | 2022 |
|
Kynurenine promotes neonatal heart regeneration by stimulating cardiomyocyte proliferation and cardiac angiogenesis.
Zhang D, Ning J, Ramprasath T, Yu C, Zheng X, Song P, Xie Z, Zou MH |
Nature Communications | 2022 |
|
Interleukin 4/13 signaling in cardiac regeneration and repair.
Bakhshian Nik A, Alvarez-Argote S, O'Meara CC |
American journal of physiology. Heart and circulatory physiology | 2022 |
|
Macrophages trigger cardiomyocyte proliferation by increasing epicardial vegfaa expression during larval zebrafish heart regeneration.
Bruton FA, Kaveh A, Ross-Stewart KM, Matrone G, Oremek MEM, Solomonidis EG, Tucker CS, Mullins JJ, Lucas CD, Brittan M, Taylor JM, Rossi AG, Denvir MA |
Developmental Cell | 2022 |
|
To regenerate or not to regenerate: Vertebrate model organisms of regeneration-competency and -incompetency
Aztekin C, Storer MA |
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society | 2022 |
|
Mending a broken heart—targeting cardiomyocyte regeneration: a literature review
Jin C, Zhu S, Zhao T, Deng J, Xiang M, Ma H |
Annals of translational medicine | 2022 |
|
The cell-autonomous and non-cell-autonomous roles of the Hippo pathway in heart regeneration.
Liu S, Li RG, Martin JF |
Journal of Molecular and Cellular Cardiology | 2022 |
|
Characterization of diverse populations of sinoatrial node cells and their proliferation potential at single nucleus resolution
Qu JH, Telljohann R, Byshkov R, Lakatta EG |
Heliyon | 2022 |
|
Renewal of embryonic and neonatal-derived cardiac-resident macrophages in response to environmental cues abrogated their potential to promote cardiomyocyte proliferation via Jagged-1–Notch1
Chen R, Zhang S, Liu F, Xia L, Wang C, Sandoghchian Shotorbani S, Xu H, Chakrabarti S, Peng T, Su Z |
Acta pharmaceutica Sinica. B | 2022 |
|
The regenerative response of cardiac interstitial cells
Rolland L, Harrington A, Faucherre A, Abaroa JM, Gangatharan G, Gamba L, Severac D, Pratlong M, Moore-Morris T, Jopling C |
Journal of Molecular Cell Biology | 2022 |
|
Integrative biology of injury in animals
Rennolds CW, Bely AE |
Biological reviews of the Cambridge Philosophical Society | 2022 |
|
Regenerative inflammation: When immune cells help to re-build tissues
Caballero-Sánchez N, Alonso-Alonso S, Nagy L |
The FEBS journal | 2022 |
|
Immunoengineering strategies to enhance vascularization and tissue regeneration.
Zarubova J, Hasani-Sadrabadi MM, Ardehali R, Li S |
Advanced Drug Delivery Reviews | 2022 |
|
Fibroblasts orchestrate cellular crosstalk in the heart through the ECM
Bowers SL, Meng Q, Molkentin JD |
2022 | |
|
Targeting calcineurin induces cardiomyocyte proliferation in adult mice.
Lam NT, Nguyen NUN, Ahmed MS, Hsu CC, Rios Coronado PE, Li S, Menendez-Montes I, Thet S, Elhelaly WM, Xiao F, Wang X, Williams NS, Canseco DC, Red-Horse K, Rothermel BA, Sadek HA |
Nature cardiovascular research | 2022 |
|
Untangling Local Pro-Inflammatory, Reparative, and Regulatory Damage-Associated Molecular-Patterns (DAMPs) Pathways to Improve Transplant Outcomes
GK Dwyer, HR Turnquist |
Frontiers in immunology | 2021 |
|
The role of lymphangiogenesis in cardiovascular diseases and heart transplantation
RC Ji |
Heart Failure Reviews | 2021 |
|
The evolving cardiac lymphatic vasculature in development, repair and regeneration
K Klaourakis, JM Vieira, PR Riley |
Nature Reviews Cardiology | 2021 |
|
Resident cardiac macrophages mediate adaptive myocardial remodeling
NR Wong, J Mohan, BJ Kopecky, S Guo, L Du, J Leid, G Feng, I Lokshina, O Dmytrenko, H Luehmann, G Bajpai, L Ewald, L Bell, N Patel, A Bredemeyer, CJ Weinheimer, JM Nigro, A Kovacs, S Morimoto, PO Bayguinov, MR Fisher, WT Stump, M Greenberg, JA Fitzpatrick, S Epelman, D Kreisel, R Sah, Y Liu, H Hu, KJ Lavine |
Immunity | 2021 |
|
Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart
TJ Cahill, X Sun, C Ravaud, CV del Campo, K Klaourakis, IE Lupu, A M., C Browne, SE Jacobsen, DR Greaves, DG Jackson, SA Cowley, W James, RP Choudhury, JM Vieira, PR Riley |
Development (Cambridge, England) | 2021 |
|
Molecular regulation of myocardial proliferation and regeneration
L Zheng, J Du, Z Wang, Q Zhou, X Zhu, JW Xiong |
Cell Regeneration | 2021 |
|
New Insights and Novel Therapeutic Potentials for Macrophages in Myocardial Infarction
Z Zhang, J Tang, X Cui, B Qin, J Zhang, L Zhang, H Zhang, G Liu, W Wang, J Zhang |
Inflammation | 2021 |
|
Driving regeneration, instead of healing, in adult mammals: the decisive role of resident macrophages through efferocytosis
L Rabiller, V Robert, A Arlat, E Labit, M Ousset, M Salon, A Coste, LD Costa-Fernandes, P Monsarrat, B Ségui, M André, C Guissard, ML Renoud, M Silva, G Mithieux, I Raymond-Letron, L Pénicaud, A Lorsignol, L Casteilla, CD Berthézène, B Cousin |
npj Regenerative Medicine | 2021 |
|
Regulation of cardiomyocyte fate plasticity: a key strategy for cardiac regeneration
R Gong, Z Jiang, N Zagidullin, T Liu, B Cai |
Signal Transduction and Targeted Therapy | 2021 |
|
Reawakening the Intrinsic Cardiac Regenerative Potential: Molecular Strategies to Boost Dedifferentiation and Proliferation of Endogenous Cardiomyocytes
C Bongiovanni, F Sacchi, SD Pra, E Pantano, C Miano, MB Morelli, G D'Uva |
Frontiers in Cardiovascular Medicine | 2021 |
|
A double-edged sword of immuno-microenvironment in cardiac homeostasis and injury repair
K Sun, Y Li, J Jin |
Signal Transduction and Targeted Therapy | 2021 |
|
Biocompatibility Evolves: Phenomenology to Toxicology to Regeneration
L Crawford, M Wyatt, J Bryers, B Ratner |
Advanced Healthcare Materials | 2021 |
|
Autophagy, Mesenchymal Stem Cell Differentiation, and Secretion
M Menshikov, E Zubkova, I Stafeev, Y Parfyonova |
Biomedicines | 2021 |
|
Immune cell dilemma in ischemic cardiomyopathy: to heal or not to heal
S Nehra, RJ Gumina, SS Bansal |
Current Opinion in Physiology | 2021 |
|
Repression of Osmr and Fgfr1 by miR-1/133a prevents cardiomyocyte dedifferentiation and cell cycle entry in the adult heart
M Valussi, J Besser, K Wystub-Lis, S Zukunft, M Richter, T Kubin, T Boettger, T Braun |
Science Advances | 2021 |
|
Cardiac cell type-specific responses to injury and contributions to heart regeneration
W Zhang, J Liang, P Han |
Cell Regeneration | 2021 |
|
Targeting Inflammation after Myocardial Infarction: A Therapeutic Opportunity for Extracellular Vesicles?
M Viola, SC de Jager, JP Sluijter |
International journal of molecular sciences | 2021 |
|
Celecoxib alleviates pathological cardiac hypertrophy and fibrosis via M1-like macrophage infiltration in neonatal mice
Y Zhao, Q Zheng, H Gao, M Cao, H Wang, R Chang, C Zeng |
iScience | 2021 |
|
Near Complete Repair After Myocardial Infarction in Adult Mice by Altering the Inflammatory Response With Intramyocardial Injection of α-Gal Nanoparticles
U Galili, Z Zhu, J Chen, JW Goldufsky, GL Schaer |
Frontiers in Cardiovascular Medicine | 2021 |
|
Tissue Regeneration: The Dark Side of Opioids
CD Berthézène, L Rabiller, G Jourdan, B Cousin, L Pénicaud, L Casteilla, A Lorsignol |
International journal of molecular sciences | 2021 |
|
Morpho-functional changes of cardiac telocytes in isolated atrial amyloidosis in patients with atrial fibrillation
TV Sukhacheva, NV Nizyaeva, MV Samsonova, AL Cherniaev, AA Burov, MV Iurova, AI Shchegolev, RA Serov, GT Sukhikh |
Scientific Reports | 2021 |
|
Identification of Novel and Potent Modulators Involved in Neonatal Cardiac Regeneration
GS Aslan, F Polat, SN Eren, D Yucel, S Arbatli, A Cumbul, F Kocabas |
Pediatric Cardiology | 2021 |
|
Navigating the Crossroads of Cell Therapy and Natural Heart Regeneration
S Elde, H Wang, YJ Woo |
Frontiers in Cell and Developmental Biology | 2021 |
|
Finding Solutions for Fibrosis: Understanding the Innate Mechanisms Used by Super‐Regenerator Vertebrates to Combat Scarring
F Durant, JL Whited |
Advanced Science | 2021 |
|
Gut Lactobacillus Level Is a Predictive Marker for Coronary Atherosclerotic Lesions Progress and Prognosis in Patients With Acute Coronary Syndrome
J Gao, J Wang, LL Zhao, TT Yao, Y Chen, J Ma, X Zhang, JX Wang, Y Wang, Z Cui, Y Liu |
Frontiers in Cellular and Infection Microbiology | 2021 |
|
The Roles of Macrophages in Heart Regeneration and Repair After Injury
Y Gao, N Qian, J Xu, Y Wang |
Frontiers in Cardiovascular Medicine | 2021 |
|
Can polarization of macrophage metabolism enhance cardiac regeneration?
C Lantz, A Becker, EB Thorp |
Journal of Molecular and Cellular Cardiology | 2021 |
|
A Roadmap to Heart Regeneration Through Conserved Mechanisms in Zebrafish and Mammals
KD Brezitski, AW Goff, P DeBenedittis, R Karra |
Current Cardiology Reports | 2021 |
|
Injectable Myocardial Matrix Hydrogel Mitigates Negative Left Ventricular Remodeling in a Chronic Myocardial Infarction Model
MD Diaz, E Tran, M Spang, R Wang, R Gaetani, CG Luo, R Braden, RC Hill, KC Hansen, AN DeMaria, KL Christman |
JACC: Basic to Translational Science | 2021 |
|
Progress in cardiac research: from rebooting cardiac regeneration to a complete cell atlas of the heart
SM Davidson, T Padró, S Bollini, G Vilahur, DJ Duncker, PC Evans, T Guzik, IE Hoefer, J Waltenberger, J Wojta, C Weber |
Cardiovascular Research | 2021 |
|
Cell Cycle Withdrawal Limit the Regenerative Potential of Neonatal Cardiomyocytes
H Yan, X Rao, R Wang, S Zhu, R Liu, X Zheng |
Cardiovascular Engineering and Technology | 2021 |
|
Genetic, epigenetic, and post‐transcriptional basis of divergent tissue regenerative capacities among vertebrates
S Khyeam, S Lee, GN Huang |
2021 | |
|
The Evolving Roles of Cardiac Macrophages in Homeostasis, Regeneration, and Repair
S Alvarez-Argote, CC OMeara |
International journal of molecular sciences | 2021 |
|
Inflammation induces zebrafish regeneration
M Iribarne |
NEURAL REGEN RES | 2021 |
|
Cardiac regenerative capacity: an evolutionary afterthought?
PD Nguyen, DE de Bakker, J Bakkers |
Cellular and Molecular Life Sciences | 2021 |
|
Protocol for cryoinjury model in neonatal mice for heart regeneration and repair research
Y Zhao, R Chang, C Zeng |
2021 | |
|
Early Postnatal Cardiac Stress Does Not Influence Ventricular Cardiomyocyte Cell-Cycle Withdrawal
M Günthel, K van Duijvenboden, J Jeremiasse, MJ van den Hoff, VM Christoffels |
Journal of Cardiovascular Development and Disease | 2021 |
|
Vertebrate cardiac regeneration: evolutionary and developmental perspectives
S Cutie, GN Huang |
Cell Regeneration | 2021 |
|
Immunomodulation for optimal cardiac regeneration: insights from comparative analyses
LF Trajano, N Smart |
npj Regenerative Medicine | 2021 |
|
Cardiac regeneration in the axolotl is unaffected by alterations in leukocyte numbers induced by lipopolysaccharide and prednisolone
K Pedersen, RK Rasmussen, A Dittrich, H Lauridsen |
BMC Research Notes | 2021 |
|
Unlocking the Secrets of the Regenerating Fish Heart: Comparing Regenerative Models to Shed Light on Successful Regeneration
HG Potts, WT Stockdale, MT Mommersteeg |
Journal of Cardiovascular Development and Disease | 2021 |
|
Identification of the Adult Hematopoietic Liver as the Primary Reservoir for the Recruitment of Pro-regenerative Macrophages Required for Salamander Limb Regeneration
RJ Debuque, AJ Hart, GH Johnson, NA Rosenthal, JW Godwin |
Frontiers in Cell and Developmental Biology | 2021 |
|
Functional coordination of non‐myocytes plays a key role in adult zebrafish heart regeneration
H Ma, Z Liu, Y Yang, D Feng, Y Dong, TA Garbutt, Z Hu, L Wang, C Luan, CD Cooper, Y Li, JD Welch, L Qian, J Liu |
EMBO reports | 2021 |
|
Age-Related Pathways in Cardiac Regeneration: A Role for lncRNAs?
F Santos, M Correia, S Nóbrega-Pereira, BB de Jesus |
Frontiers in physiology | 2021 |
|
Biosynthesis of α-Gal Epitopes (Galα1-3Galβ1-4GlcNAc-R) and Their Unique Potential in Future α-Gal Therapies
U Galili |
Frontiers in Molecular Biosciences | 2021 |
|
Histopathological and immunohistochemical aspects of bone tissue in aseptic necrosis of the femoral head
RM Vicaş |
Romanian Journal of Morphology and Embryology | 2021 |
|
The Role of the Immune Microenvironment in Bone Regeneration
N Yang, Y Liu |
International journal of medical sciences | 2021 |
|
A complete heart regeneration model with inflammation as a key component
C Liu, L Wang, X Wang, X Hou |
Experimental Animals | 2021 |
|
Genome-wide expression of the residual lung reacting to experimental Pneumonectomy
V Napolioni, F Bianconi, R Potenza, FM Carpi, V Ludovini, M Picciolini, FR Tofanetti, A Bufalari, S Pallotti, C Poggi, M Anile, N Daddi, F Venuta, F Puma, J Vannucci |
BMC Genomics | 2021 |
|
Monomeric CRP Aggravates Myocardial Injury After Myocardial Infarction by Polarizing the Macrophage to Pro-Inflammatory Phenotype Through JNK Signaling Pathway
Z Zha, Y Cheng, L Cao, Y Qian, X Liu, Y Guo, J Wang |
Journal of inflammation research | 2021 |
|
Regenerative potential of epicardium-derived extracellular vesicles mediated by conserved miRNA transfer
C del Campo, N Liaw, M Gunadasa-Rohling, M Matthaei, L Braga, T Kennedy, G Salinas, N Voigt, M Giacca, W Zimmermann, P Riley |
Cardiovascular Research | 2021 |
|
Guidelines for in vivo mouse models of myocardial infarction
M Lindsey, K Brunt, J Kirk, P Kleinbongard, J Calvert, L de Castro Brás, K DeLeon-Pennell, D Re, N Frangogiannis, S Frantz, R Gumina, G Halade, S Jones, R Ritchie, F Spinale, E Thorp, C Ripplinger, Z Kassiri |
American journal of physiology. Heart and circulatory physiology | 2021 |
|
M2c Macrophages enhance phalange regeneration of amputated mice digits in an organ co-culture system
Fatemeh Bijarchian, Leila Taghiyar, Zahra Azhdari, Mohamadreza Baghaban Eslaminejad |
Iranian Journal of Basic Medical Sciences | 2021 |
|
Autologous Lipofilling Improves Clinical Outcome in Patients With Symptomatic Dermal Scars Through Induction of a Pro-Regenerative Immune Response
M Spiekman, D Francia, D Mossel, L Brouwer, G Diercks, K Vermeulen, M Folkertsma, M Ghods, J Kzhyshkowska, H Klüter, G Krenning, B van der Lei, M Harmsen |
Aesthetic Surgery Journal | 2021 |
|
MACROPHAGE EFFEROCYTOSIS IN CARDIAC PATHOPHYSIOLOGY AND REPAIR
Yutian L, Qianqian L, Fan GC |
Shock (Augusta, Ga.) | 2021 |
|
Characterizing Neonatal Heart Maturation, Regeneration, and Scar Resolution Using Spatial Transcriptomics
Misra A, Baker CD, Pritchett EM, Burgos Villar KN, Ashton JM, Small EM |
Journal of Cardiovascular Development and Disease | 2021 |
|
From Autonomy to Integration, From Integration to Dynamically Balanced Integrated Co-existence: Non-aging as the Third Stage of Development
Salnikov L, Baramiya MG |
2021 | |
|
Mechanisms and strategies for a therapeutic cardiac immune response
Ferrari I, Vagnozzi RJ |
Journal of molecular and cellular cardiology | 2021 |
|
Sectm1a Facilitates Protection against Inflammation-Induced Organ Damage through Promoting TRM Self-Renewal
X Mu, H Fan, P Wang, Y Li, K Domenico, Q Li, X Wang, K Essandoh, J Chen, T Peng, GC Fan |
Molecular Therapy | 2020 |
|
Autophagy Activation in Zebrafish Heart Regeneration
MN Chávez, RA Morales, C López-Crisosto, JC Roa, ML Allende, S Lavandero |
Scientific Reports | 2020 |
|
The immune response to infection in the bladder
LL Mariano, MA Ingersoll |
Nature Reviews Urology | 2020 |
|
Cardiac Regeneration: Methods and Protocols
KD Poss, B Kühn |
2020 | |
|
Role of Cardiac Macrophages on Cardiac Inflammation, Fibrosis and Tissue Repair
WP Lafuse, DJ Wozniak, MV Rajaram |
Cells | 2020 |
|
Cellular and Molecular Mechanism of Cardiac Regeneration: A Comparison of Newts, Zebrafish, and Mammals
L de Wit, J Fang, K Neef, J Xiao, PA Doevendans, RM Schiffelers, Z Lei, JP Sluijter |
Biomolecules | 2020 |
|
The Hippo Pathway in Cardiac Regeneration and Homeostasis: New Perspectives for Cell-Free Therapy in the Injured Heart
M Zheng, J Jacob, SH Hung, J Wang |
Biomolecules | 2020 |
|
Apoptosis of hematopoietic progenitor-derived adipose tissue–resident macrophages contributes to insulin resistance after myocardial infarction
SB Vasamsetti, E Coppin, X Zhang, J Florentin, S Koul, M Götberg, AS Clugston, F Thoma, J Sembrat, GC Bullock, D Kostka, CM Croix, A Chattopadhyay, M Rojas, SR Mulukutla, P Dutta |
Science Translational Medicine | 2020 |
|
Message in a Bottle: Upgrading Cardiac Repair into Rejuvenation
C Balbi, A Costa, L Barile, S Bollini |
Cells | 2020 |
|
Potential functions of embryonic cardiac macrophages in angiogenesis, lymphangiogenesis and extracellular matrix remodeling
G Gula, S Rumiński, J Niderla-Bielińska, A Jasińska, E Kiernozek, E Jankowska-Steifer, A Flaht-Zabost, A Ratajska |
Histochemistry and Cell Biology | 2020 |
|
Senescent cells and macrophages: key players for regeneration?
S S., E Emmerson |
Open Biology | 2020 |
|
Nitrite Improves Heart Regeneration in Zebrafish
ER Rochon, MA Missinato, J Xue, J Tejero, M Tsang, MT Gladwin, P Corti |
Antioxidants & Redox Signaling | 2020 |
|
Macrophages in the pancreas: Villains by circumstances, not necessarily by actions
AF Cruz, R Rohban, F Esni |
Immunity, Inflammation and Disease | 2020 |
|
Macrophage lineages in heart valve development and disease
AJ Kim, N Xu, KE Yutzey |
Cardiovascular Research | 2020 |
|
Mechanisms of Neonatal Heart Regeneration
AC Cardoso, AH Pereira, HA Sadek |
Current Cardiology Reports | 2020 |
|
Therapeutic silencing miR-146b-5p improves cardiac remodeling in a porcine model of myocardial infarction by modulating the wound reparative phenotype
Y Liao, H Li, H Cao, Y Dong, L Gao, Z Liu, J Ge, H Zhu |
Protein & Cell | 2020 |
|
New Approaches to Target Inflammation in Heart Failure: Harnessing Insights from Studies of Immune Cell Diversity
AJ Rhee, KJ Lavine |
Annual Review of Physiology | 2020 |
|
Macrophage Activities in Myocardial Infarction and Heart Failure
SE Duncan, S Gao, M Sarhene, JW Coffie, D Linhua, X Bao, Z Jing, S Li, R Guo, J Su, G Fan |
Cardiology Research and Practice | 2020 |
|
Secretome-Based Screening in Target Discovery
M Ding, H Tegel, Å Sivertsson, S Hober, A Snijder, M Ormö, PE Strömstedt, R Davies, LH Schiavone |
SLAS Discovery | 2020 |
|
Resident cardiac macrophages: crucial modulators of cardiac (patho)physiology
M Sansonetti, FJ Waleczek, M Jung, T Thum, F Perbellini |
Basic Research in Cardiology | 2020 |
|
Cell-Type-Specific Gene Regulatory Networks Underlying Murine Neonatal Heart Regeneration at Single-Cell Resolution
Z Wang, M Cui, AM Shah, W Tan, N Liu, R Bassel-Duby, EN Olson |
Cell Reports | 2020 |
|
The Role of the Epicardium During Heart Development and Repair
P Quijada, MA Trembley, EM Small |
Circulation research | 2020 |
|
Young at Heart: Combining Strategies to Rejuvenate Endogenous Mechanisms of Cardiac Repair
E Maghin, P Garbati, R Quarto, M Piccoli, S Bollini |
Frontiers in Bioengineering and Biotechnology | 2020 |
|
Imaging Cardiovascular and Lung Macrophages With the Positron Emission Tomography Sensor 64 Cu-Macrin in Mice, Rabbits, and Pigs
M Nahrendorf, FF Hoyer, AE Meerwaldt, MM van Leent, ML Senders, C Calcagno, PM Robson, G Soultanidis, C Pérez-Medina, AJ Teunissen, YC Toner, K Ishikawa, K Fish, K Sakurai, EM van Leeuwen, ED Klein, AM Sofias, T Reiner, D Rohde, AD Aguirre, G Wojtkiewicz, S Schmidt, Y Iwamoto, D Izquierdo-Garcia, P Caravan, FK Swirski, R Weissleder, WJ Mulder |
Circulation. Cardiovascular imaging | 2020 |
|
Cardiac Nestin+ Mesenchymal Stromal Cells Enhance Healing of Ischemic Heart through Periostin-Mediated M2 Macrophage Polarization
Y Liao, G Li, X Zhang, W Huang, D Xie, G Dai, S Zhu, D Lu, Z Zhang, J Lin, B Wu, W Lin, Y Chen, Z Chen, C Peng, M Wang, X Chen, MH Jiang, AP Xiang |
Molecular Therapy | 2020 |
|
Liposomal delivery of azithromycin enhances its immunotherapeutic efficacy and reduces toxicity in myocardial infarction
A Al-Darraji, RR Donahue, H Tripathi, H Peng, BM Levitan, L Chelvarajan, D Haydar, E Gao, D Henson, JC Gensel, DJ Feola, VJ Venditto, A Abdel-Latif |
Scientific Reports | 2020 |
|
Engineering Immunomodulatory Biomaterials for Regenerating the Infarcted Myocardium
N Bloise, I Rountree, C Polucha, G Montagna, L Visai, KL Coulombe, F Munarin |
Frontiers in Bioengineering and Biotechnology | 2020 |
|
Cardiomyocyte Senescence and Cellular Communications Within Myocardial Microenvironments
X Tang, PH Li, HZ Chen |
Frontiers in Endocrinology | 2020 |
|
Cardiac fibroblast derived matrix-educated macrophages express VEGF and IL-6, and recruit mesenchymal stromal cells
S Roy, K Spinali, EG Schmuck, JA Kink, P Hematti, AN Raval |
2020 | |
|
Exosomes released from educated mesenchymal stem cells accelerate cutaneous wound healing via promoting angiogenesis
X Qiu, J Liu, C Zheng, Y Su, L Bao, B Zhu, S Liu, L Wang, X Wang, Y Wang, W Zhao, J Zhou, Z Deng, S Liu, Y Jin |
Cell Proliferation | 2020 |
|
Macrophages directly contribute collagen to scar formation during zebrafish heart regeneration and mouse heart repair
FC Simões, TJ Cahill, A Kenyon, D Gavriouchkina, JM Vieira, X Sun, D Pezzolla, C Ravaud, E Masmanian, M Weinberger, S Mayes, ME Lemieux, DN Barnette, M Gunadasa-Rohling, RM Williams, DR Greaves, LA Trinh, SE Fraser, SL Dallas, RP Choudhury, T Sauka-Spengler, PR Riley |
Nature Communications | 2020 |
|
Cardiomyocyte cell cycling, maturation, and growth by multinucleation in postnatal swine
N Velayutham, CM Alfieri, EJ Agnew, KW Riggs, RS Baker, SR Ponny, F Zafar, KE Yutzey |
Journal of Molecular and Cellular Cardiology | 2020 |
|
Research progress on myocardial regeneration: what is new?
C Du, Y Fan, YF Li, TW Wei, LS Wang |
Chinese Medical Journal | 2020 |
|
Complex Tissue Regeneration in Mammals Is Associated With Reduced Inflammatory Cytokines and an Influx of T Cells
TR Gawriluk, J Simkin, CK Hacker, JM Kimani, SG Kiama, VO Ezenwa, AW Seifert |
Frontiers in immunology | 2020 |
|
YAP/TAZ deficiency reprograms macrophage phenotype and improves infarct healing and cardiac function after myocardial infarction
MM Mia, DM Cibi, SA Ghani, W Song, N Tee, S Ghosh, J Mao, EN Olson, MK Singh, TC Freeman |
PLoS Biology | 2020 |
|
Resident macrophages as potential therapeutic targets for cardiac ageing and injury
S Zhang, R Chen, S Chakrabarti, Z Su |
IBMS BoneKEy | 2020 |
|
Electrocardiogram-gated Kilohertz Visualisation (EKV) Ultrasound Allows Assessment of Neonatal Cardiac Structural and Functional Maturation and Longitudinal Evaluation of Regeneration After Injury
RF Castellan, A Thomson, CM Moran, GA Gray |
Ultrasound in Medicine & Biology | 2020 |
|
Neonatal Heart Responds to Pressure Overload With Differential Alterations in Various Cardiomyocyte Maturation Programs That Accommodate Simultaneous Hypertrophy and Hyperplasia
X Ding, S Wang, Y Wang, J Yang, N Bao, J Liu, Z Zhang |
Frontiers in Cell and Developmental Biology | 2020 |
|
Transplantation of murine neonatal cardiac macrophage improves adult cardiac repair
Y Li, H Li, J Pei, S Hu, Y Nie |
Cellular and Molecular Immunology | 2020 |
|
Beneficial effects of IL-4 and IL-6 on rat neonatal target cardiac cells
C Zogbi, NC Oliveira, D Levy, SP Bydlowski, V Bassaneze, EA Neri, JE Krieger |
Scientific Reports | 2020 |
|
Role of Macrophages and Microglia in Zebrafish Regeneration
SR Var, CA Byrd-Jacobs |
International journal of molecular sciences | 2020 |
|
Harnessing Cardiac Regeneration as a Potential Therapeutic Strategy for AL Cardiac Amyloidosis
S Joshi, A Evangelisti, R Liao, KM Alexander |
Current Cardiology Reports | 2020 |
|
Natural Heart Regeneration in a Neonatal Rat Myocardial Infarction Model
H Wang, MJ Paulsen, CE Hironaka, HS Shin, JM Farry, AD Thakore, J Jung, HJ Lucian, A Eskandari, S Anilkumar, MA Wu, MC Cabatu, AN Steele, LM Stapleton, Y Zhu, YJ Woo |
Cells | 2020 |
|
Lens regeneration in humans: using regenerative potential for tissue repairing
Z Liu, R Wang, H Lin, Y Liu |
Annals of translational medicine | 2020 |
|
Exosomes Derived from Bone Marrow Stromal Cells (BMSCs) Enhance Tendon-Bone Healing by Regulating Macrophage Polarization
Y Shi, X Kang, Y Wang, X Bian, G He, M Zhou, K Tang |
Medical science monitor : international medical journal of experimental and clinical research | 2020 |
|
Tissue-Resident Macrophages in the Control of Infection and Resolution of Inflammation
X Mu, Y Li, G Fan |
Shock | 2020 |
|
Induction of cardiomyocyte proliferation and angiogenesis protects neonatal mice from pressure overload-associated maladaptation
Mona Malek Mohammadi, Aya Abouissa, Azizah Isyatul, Yinou Xie, Julio Cordero, Amir Shirvani, Anna Gigina, Maren Engelhardt, Felix A Trogisch, Robert Geffers, Gergana Dobreva, Johann Bauersachs, Joerg Heineke |
JCI Insight | 2019 |
|
Anti-inflammatory activity of ANGPTL4 facilitates macrophage polarization to induce cardiac repair
Dong Im Cho, Hye-jin Kang, Ju Hee Jun, Gwang Hyeon Eom, Hyang Hee Cho, Mi Ra Kim, Meeyoung Cho, Hye-yun Jeong, Hyen Chung Cho, Moon Hwa Hong, Yong Sook Kim, Youngkeun Ahn |
JCI Insight | 2019 |
|
Specific macrophage populations promote both cardiac scar deposition and subsequent resolution in adult zebrafish
L Bevan, ZW Lim, B Venkatesh, PR Riley, P Martin, RJ Richardson |
Cardiovascular Research | 2019 |
|
The Cardiac Microenvironment Instructs Divergent Monocyte Fates and Functions in Myocarditis
X Hou, G Chen, W Bracamonte-Baran, HS Choi, NL Diny, J Sung, D Hughes, T Won, MK Wood, MV Talor, DJ Hackam, K Klingel, G Davogustto, H Taegtmeyer, I Coppens, JG Barin, D Čiháková |
Cell Reports | 2019 |
|
Mechanistic basis of neonatal heart regeneration revealed by transcriptome and histone modification profiling
Z Wang, M Cui, AM Shah, W Ye, W Tan, YL Min, GA Botten, JM Shelton, N Liu, R Bassel-Duby, EN Olson |
Proceedings of the National Academy of Sciences | 2019 |
|
Three in a Box: Understanding Cardiomyocyte, Fibroblast, and Innate Immune Cell Interactions to Orchestrate Cardiac Repair Processes
S Psarras, D Beis, S Nikouli, M Tsikitis, Y Capetanaki |
Frontiers in Cardiovascular Medicine | 2019 |
|
Emerging Roles for Immune Cells and MicroRNAs in Modulating the Response to Cardiac Injury
A Rodriguez, V Yin |
Journal of Cardiovascular Development and Disease | 2019 |
|
Meningeal Foam Cells and Ependymal Cells in Axolotl Spinal Cord Regeneration
N Enos, H Takenaka, S Scott, HV Salfity, M Kirk, MW Egar, DA Sarria, D Slayback-Barry, T Belecky-Adams, EA Chernoff |
Frontiers in immunology | 2019 |
|
Deriving a Boolean dynamics to reveal macrophage activation with in vitro temporal cytokine expression profiles
R Ramirez, AM Herrera, J Ramirez, C Qian, DW Melton, PK Shireman, YF Jin |
BMC bioinformatics | 2019 |
|
Role of Macrophages in Cardioprotection
J Yap, HA Cabrera-Fuentes, J Irei, DJ Hausenloy, WA Boisvert |
International journal of molecular sciences | 2019 |
|
Tissue Resident CCR2− and CCR2+ Cardiac Macrophages Differentially Orchestrate Monocyte Recruitment and Fate Specification Following Myocardial Injury
G Bajpai, A Bredemeyer, W Li, K Zaitsev, AL Koenig, I Lokshina, J Mohan, B Ivey, HM Hsiao, C Weinheimer, A Kovacs, S Epelman, M Artyomov, D Kreisel, KJ Lavine |
Circulation research | 2019 |
|
Macrophage Plasticity and Function in the Eye and Heart
Z Wang, AL Koenig, KJ Lavine, RS Apte |
Trends in Immunology | 2019 |
|
Regeneration competent satellite cell niches in rat engineered skeletal muscle
M Tiburcy, A Markov, LK Kraemer, P Christalla, M RaveFraenk, HJ Fischer, HM Reichardt, WH Zimmermann |
FASEB bioAdvances | 2019 |
|
Perspectives on Directions and Priorities for Future Preclinical Studies in Regenerative Medicine
LG Shamagian, R Madonna, D Taylor, AM Climent, F Prosper, L Bras-Rosario, A Bayes-Genis, P Ferdinandy, F Fernández-Avilés, JC Belmonte, V Fuster, R Bolli |
Circulation research | 2019 |
|
Single-cell expression profiling reveals dynamic flux of cardiac stromal, vascular and immune cells in health and injury
N Farbehi, R Patrick, A Dorison, M Xaymardan, V Janbandhu, K Wystub-Lis, JW Ho, RE Nordon, RP Harvey |
eLife | 2019 |
|
Wilms Tumor 1b Expression Defines a Pro-regenerative Macrophage Subtype and Is Required for Organ Regeneration in the Zebrafish
A Sanz-Morejón, AB García-Redondo, H Reuter, IJ Marques, T Bates, M Galardi-Castilla, A Große, S Manig, X Langa, A Ernst, I Piragyte, MA Botos, JM González-Rosa, M Ruiz-Ortega, AM Briones, M Salaices, C Englert, N Mercader |
Cell Reports | 2019 |
|
Model organisms at the heart of regeneration
EL Price, JM Vieira, PR Riley |
Disease models & mechanisms | 2019 |
|
Macrophages in cardiac repair: Environmental cues and therapeutic strategies
G de Couto |
Experimental & molecular medicine | 2019 |
|
Modulation of TNFα Activity by the microRNA Let-7 Coordinates Zebrafish Heart Regeneration
AM Smith, CA Dykeman, BL King, VP Yin |
iScience | 2019 |
|
ESC Working Group on Cellular Biology of the Heart: position paper for Cardiovascular Research: tissue engineering strategies combined with cell therapies for cardiac repair in ischaemic heart disease and heart failure
R Madonna, LW Laake, HE Botker, SM Davidson, RD Caterina, FB Engel, T Eschenhagen, F Fernandez-Aviles, DJ Hausenloy, JS Hulot, S Lecour, J Leor, P Menasché, M Pesce, C Perrino, F Prunier, SV Linthout, K Ytrehus, WH Zimmermann, P Ferdinandy, JP Sluijter |
Cardiovascular Research | 2019 |
|
Cortical Bone Derived Stem Cells for Cardiac Wound Healing
S Mohsin, SR Houser |
Korean Circulation Journal | 2019 |
|
A Unique Collateral Artery Development Program Promotes Neonatal Heart Regeneration
S Das, AB Goldstone, H Wang, J Farry, G DAmato, MJ Paulsen, A Eskandari, CE Hironaka, R Phansalkar, B Sharma, S Rhee, EA Shamskhou, D Agalliu, V de Jesus Perez, YJ Woo, K Red-Horse |
Cell | 2019 |
|
Macrophages are necessary for skin regeneration during tissue expansion
J Ding, L Lei, S Liu, Y Zhang, Z Yu, Y Su, X Ma |
Journal of Translational Medicine | 2019 |
|
Decellularized neonatal cardiac extracellular matrix prevents widespread ventricular remodeling in adult mammals after myocardial infarction
Z Wang, DW Long, Y Huang, WC Chen, K Kim, Y Wang |
Acta Biomaterialia | 2019 |
|
Endocardially Derived Macrophages Are Essential for Valvular Remodeling
A Shigeta, V Huang, J Zuo, R Besada, Y Nakashima, Y Lu, Y Ding, M Pellegrini, RP Kulkarni, T Hsiai, A Deb, B Zhou, H Nakano, A Nakano |
Developmental Cell | 2019 |
|
Differential Response to Injury in Fetal and Adolescent Sheep Hearts in the Immediate Post-myocardial Infarction Period
MC Lock, JR Darby, JY Soo, DA Brooks, SR Perumal, JB Selvanayagam, M Seed, CK Macgowan, ER Porrello, RL Tellam, JL Morrison |
Frontiers in physiology | 2019 |
|
Anemia induces gut inflammation and injury in an animal model of preterm infants
CM Arthur, D Nalbant, HA Feldman, BJ Saeedi, J Matthews, BS Robinson, NA Kamili, A Bennett, GA Cress, M SolaVisner, RM Jones, MB Zimmerman, AS Neish, RM Patel, P Nopoulos, MK Georgieff, JD Roback, JA Widness, CD Josephson, SR Stowell |
Transfusion | 2019 |
|
The long non-coding road to endogenous cardiac regeneration
AR Afify |
Heart Failure Reviews | 2019 |
|
Understanding the Metabolic Profile of Macrophages During the Regenerative Process in Zebrafish
LC Paredes, NO Camara, TT Braga |
Frontiers in physiology | 2019 |
|
Single-cell imaging and transcriptomic analyses of endogenous cardiomyocyte dedifferentiation and cycling
Y Zhang, N Gago-Lopez, N Li, Z Zhang, N Alver, Y Liu, AM Martinson, A Mehri, WR MacLellan |
Cell Discovery | 2019 |
|
Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner
J Li, KY Yang, RC Tam, VW Chan, HY Lan, S Hori, B Zhou, KO Lui |
Theranostics | 2019 |
|
Association of Rare Recurrent Copy Number Variants With Congenital Heart Defects Based on Next-Generation Sequencing Data From Family Trios
Y Liu, X Chang, J Glessner, H Qu, L Tian, D Li, K Nguyen, PM Sleiman, H Hakonarson |
Frontiers in Genetics | 2019 |
|
Postnatal Cardiac Development and Regenerative Potential in Large Mammals
N Velayutham, EJ Agnew, KE Yutzey |
Pediatric Cardiology | 2019 |
|
The effect of Substance P/Heparin conjugated PLCL polymer coating of bioinert ePTFE vascular grafts on the recruitment of both ECs and SMCs for accelerated regeneration
D Kim, JJ Chung, Y Jung, SH Kim |
Scientific Reports | 2019 |
|
Stimulating ideas for heart regeneration: the future of nerve-directed heart therapy
EB Brandt, SJ Bashar, AI Mahmoud |
Bioelectronic medicine | 2019 |
|
Neonatal annulus fibrosus regeneration occurs via recruitment and proliferation of Scleraxis-lineage cells
OM Torre, V Mroz, AR Benitez, AH Huang, JC Iatridis |
npj Regenerative Medicine | 2019 |
|
Phenotypic Screen with the Human Secretome Identifies FGF16 as Inducing Proliferation of iPSC-Derived Cardiac Progenitor Cells
K Jennbacken, F Wågberg, U Karlsson, J Eriksson, L Magnusson, M Chimienti, P Ricchiuto, J Bernström, M Ding, D Ross-Thriepland, Y Xue, D Peiris, T Aastrup, H Tegel, S Hober, Å Sivertsson, M Uhlén, PE Strömstedt, R Davies, LH Schiavone |
International journal of molecular sciences | 2019 |
|
Recent advances in myocardial regeneration strategy
K Sheng, Y Nie, B Gao |
J INT MED RES | 2019 |
|
Isolation of Macrophage Subsets and Stromal Cells from Human and Mouse Myocardial Specimens
G Bajpai, KJ Lavine |
Journal of visualized experiments : JoVE | 2019 |
|
Looking back and thinking forwards - 15 years of cardiology and cardiovascular research.
Kalman JM, Lavandero S, Mahfoud F, Nahrendorf M, Yacoub MH, Zhao D |
Nature reviews. Cardiology | 2019 |
|
Splenic leukocytes define the resolution of inflammation in heart failure
GV Halade, PC Norris, V Kain, CN Serhan, KA Ingle |
Science signaling | 2018 |
|
TLR3 Mediates Repair and Regeneration of Damaged Neonatal Heart through Glycolysis Dependent YAP1 Regulated miR-152 Expression
X Wang, T Ha, L Liu, Y Hu, R Kao, J Kalbfleisch, D Williams, C Li |
Cell Death and Differentiation | 2018 |
|
Macrophages and Cardiovascular Health
V Frodermann, M Nahrendorf |
Physiological reviews | 2018 |
|
Resident and Monocyte-Derived Macrophages in Cardiovascular Disease
L Honold, M Nahrendorf |
Circulation research | 2018 |
|
Heart Regeneration in Adult Mammals after Myocardial Damage
Baiping Cui, Yufan Zheng, Lihua Sun, Ting Shi, Ziyu Shi, Lijue Wang, Guoying Huang, Ning Sun |
ACTA CARDIOL SIN | 2018 |
|
Exogenous CXCL4 infusion inhibits macrophage phagocytosis by limiting CD36 signalling to enhance post-myocardial infarction cardiac dilation and mortality
ML Lindsey, M Jung, A Yabluchanskiy, PL Cannon, RP Iyer, ER Flynn, KY DeLeon-Pennell, FM Valerio, CL Harrison, CM Ripplinger, ME Hall, Y Ma |
Cardiovascular Research | 2018 |
|
Therapeutic approaches for cardiac regeneration and repair
H Hashimoto, EN Olson, R Bassel-Duby |
Nature Reviews Cardiology | 2018 |
|
The Macrophage in Cardiac Homeostasis and Disease
KJ Lavine, AR Pinto, S Epelman, BJ Kopecky, X Clemente-Casares, J Godwin, N Rosenthal, JC Kovacic |
Journal of the American College of Cardiology | 2018 |
|
Cardiomyocytes and Macrophages Discourse on the Method to Govern Cardiac Repair
I Gomez, V Duval, JS Silvestre |
Frontiers in Cardiovascular Medicine | 2018 |
|
Immune responses in cardiac repair and regeneration: a comparative point of view
SL Lai, R Marín-Juez, DY Stainier |
Cellular and Molecular Life Sciences | 2018 |
|
Comparative regenerative mechanisms across different mammalian tissues
SE Iismaa, X Kaidonis, AM Nicks, N Bogush, K Kikuchi, N Naqvi, RP Harvey, A Husain, RM Graham |
npj Regenerative Medicine | 2018 |
|
Parallels between vertebrate cardiac and cutaneous wound healing and regeneration
RJ Richardson |
npj Regenerative Medicine | 2018 |
|
Physiology of cardiac development: from genetics to signaling to therapeutic strategies
C Sun, MI Kontaridis |
Current Opinion in Physiology | 2018 |
|
Changes in cardiac resident fibroblast physiology and phenotype in aging
JA Trial, KA Cieslik |
American journal of physiology. Heart and circulatory physiology | 2018 |
|
Myeloid cell contributions to cardiovascular health and disease
M Nahrendorf |
Nature Medicine | 2018 |
|
Distinct roles of resident and nonresident macrophages in nonischemic cardiomyopathy
X Liao, Y Shen, R Zhang, K Sugi, NT Vasudevan, MA Alaiti, DR Sweet, L Zhou, Y Qing, SL Gerson, C Fu, A Wynshaw-Boris, R Hu, MA Schwartz, H Fujioka, B Richardson, MJ Cameron, H Hayashi, JS Stamler, MK Jain |
Proceedings of the National Academy of Sciences | 2018 |
|
Syncytium calcium signaling and macrophage function in the heart
X Zhou, Z Li, Z Wang, E Chen, J Wang, F Chen, O Jones, T Tan, S Chen, H Takeshima, J Bryant, J Ma, X Xu |
Cell & Bioscience | 2018 |
|
Cardiac macrophage biology in the steady-state heart, the aging heart, and following myocardial infarction
Y Ma, AJ Mouton, ML Lindsey |
Translational research : the journal of laboratory and clinical medicine | 2018 |
|
Effect of Polarization and Chronic Inflammation on Macrophage Expression of Heparan Sulfate Proteoglycans and Biosynthesis Enzymes
M Swart, L Troeberg |
Journal of Histochemistry & Cytochemistry | 2018 |
|
Regulatory T-Cells: Potential Regulator of Tissue Repair and Regeneration
J Li, J Tan, MM Martino, KO Lui |
Frontiers in immunology | 2018 |
|
Development, Proliferation, and Growth of the Mammalian Heart
M Günthel, P Barnett, VM Christoffels |
Molecular Therapy | 2018 |
|
Transcriptional Programs and Regeneration Enhancers Underlying Heart Regeneration
I Begeman, J Kang |
Journal of Cardiovascular Development and Disease | 2018 |
|
Cell biological mechanisms in regulation of the post-infarction inflammatory response
NG Frangogiannis |
Current Opinion in Physiology | 2018 |
|
Azithromycin therapy reduces cardiac inflammation and mitigates adverse cardiac remodeling after myocardial infarction: Potential therapeutic targets in ischemic heart disease
A Al-Darraji, D Haydar, L Chelvarajan, H Tripathi, B Levitan, E Gao, VJ Venditto, JC Gensel, DJ Feola, A Abdel-Latif, Y Guo |
PloS one | 2018 |
|
Guidelines for Experimental Models of Myocardial Ischemia and Infarction
ML Lindsey, R Bolli, JM Canty, XJ Du, NG Frangogiannis, S Frantz, RG Gourdie, JW Holmes, SP Jones, R Kloner, DJ Lefer, R Liao, E Murphy, P Ping, K Przyklenk, FA Recchia, LS Longacre, CM Ripplinger, JE van Eyk, G Heusch |
American journal of physiology. Heart and circulatory physiology | 2018 |
|
Complement Receptor C5aR1 Plays an Evolutionarily Conserved Role in Successful Cardiac Regeneration
N Natarajan, Y Abbas, DM Bryant, JM Gonzalez-Rosa, M Sharpe, A Uygur, LH Cocco-Delgado, NN Ho, NP Gerard, CJ Gerard, CA MacRae, CE Burns, CG Burns, JL Whited, RT Lee |
Circulation | 2018 |
|
Ischaemia alters the effects of cardiomyocyte-derived extracellular vesicles on macrophage activation
RA Paiva, T Martins-Marques, K Jesus, T Ribeiro-Rodrigues, M Zuzarte, A Silva, L Reis, M da Silva, P Pereira, P Vader, JP Sluijter, L Gonçalves, MT Cruz, H Girao |
Journal of Cellular and Molecular Medicine | 2018 |
|
Resident cells of the myocardium: more than spectators in cardiac injury, repair and regeneration
GA Gray, IS Toor, RF Castellan, M Crisan, M Meloni |
Current Opinion in Physiology | 2018 |
|
Vegfaa instructs cardiac muscle hyperplasia in adult zebrafish
R Karra, MJ Foglia, WY Choi, C Belliveau, P DeBenedittis, KD Poss |
Proceedings of the National Academy of Sciences | 2018 |
|
Biomarkers for the identification of cardiac fibroblast and myofibroblast cells
E Tarbit, I Singh, JN Peart, RB RoseMeyer |
Heart Failure Reviews | 2018 |
|
Decoding the Heart through Next Generation Sequencing Approaches
M Pawlak, K Niescierowicz, CL Winata |
Genes & development | 2018 |
|
Neonatal Apex Resection Triggers Cardiomyocyte Proliferation, Neovascularization and Functional Recovery Despite Local Fibrosis
V Sampaio-Pinto, SC Rodrigues, TL Laundos, ED Silva, F Vasques-Nóvoa, AC Silva, RJ Cerqueira, TP Resende, N Pianca, A Leite-Moreira, G D'Uva, S Thorsteinsdóttir, P Pinto-do-Ó, DS Nascimento |
Stem Cell Reports | 2018 |
|
Angiogenesis precedes cardiomyocyte migration in regenerating mammalian hearts
AB Ingason, AB Goldstone, MJ Paulsen, AD Thakore, , BB Edwards, A Eskandari, T Bollig, AN Steele, YJ Woo |
The Journal of Thoracic and Cardiovascular Surgery | 2018 |
|
Characterizing the Key Metabolic Pathways of the Neonatal Mouse Heart Using a Quantitative Combinatorial Omics Approach
MM Lalowski, S Björk, P Finckenberg, R Soliymani, M Tarkia, G Calza, D Blokhina, S Tulokas, M Kankainen, P Lakkisto, M Baumann, E Kankuri, E Mervaala |
Frontiers in physiology | 2018 |
|
Treatment with 3-Bromo-4,5-Dihydroxybenzaldehyde Improves Cardiac Function by Inhibiting Macrophage Infiltration in Mice
N Ji, H Lou, X Gong, T Fu, S Ni |
Korean Circulation Journal | 2018 |
|
Neonatal mouse intervertebral discs heal with restored function following herniation injury
OM Torre, R Das, RE Berenblum, AH Huang, JC Iatridis |
The FASEB Journal | 2018 |
|
Mechanisms and Therapeutic Targets of Cardiac Regeneration: Closing the Age Gap
RF Castellan, M Meloni |
Frontiers in Cardiovascular Medicine | 2018 |
|
Neonatal Heart Regeneration: Comprehensive Literature Review
NT Lam, HA Sadek |
Circulation | 2018 |
|
Annulus fibrosus cell phenotypes in homeostasis and injury: implications for regenerative strategies: Annulus fibrosus cells in injury and healing
OM Torre, V Mroz, MK Bartelstein, AH Huang, JC Iatridis |
Annals of the New York Academy of Sciences | 2018 |
|
Unified nexus of macrophages and maresins in cardiac reparative mechanisms
JK Jadapalli, GV Halade |
The FASEB Journal | 2018 |
|
Role of stromal cell derived factor-1 in myocardial healing—novel insights from comparative studies in the fetal and postnatal myocardium
U Hofmann, S Frantz |
Translational Pediatrics | 2018 |
|
Incorporation of macrophages into engineered skeletal muscle enables enhanced muscle regeneration
M Juhas, N Abutaleb, JT Wang, J Ye, Z Shaikh, C Sriworarat, Y Qian, N Bursac |
Nature Biomedical Engineering | 2018 |
|
Regenerative Potential of Neonatal Porcine Hearts
W Zhu, E Zhang, M Zhao, Z Chong, C Fan, Y Tang, JD Hunter, AV Borovjagin, GP Walcott, JY Chen, G Qin, J Zhang |
Circulation | 2018 |
|
Endothelial Contributions to Zebrafish Heart Regeneration
C Fernandez, M Bakovic, R Karra |
Journal of Cardiovascular Development and Disease | 2018 |
|
Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction
SA Dick, JA Macklin, S Nejat, A Momen, X Clemente-Casares, MG Althagafi, J Chen, C Kantores, S Hosseinzadeh, L Aronoff, A Wong, R Zaman, I Barbu, R Besla, KJ Lavine, B Razani, F Ginhoux, M Husain, MI Cybulsky, CS Robbins, S Epelman |
Nature Immunology | 2018 |
|
Immunomodulation by Exosomes in Myocardial Infarction
W Pan, Y Zhu, X Meng, C Zhang, Y Yang, Y Bei |
Journal of Cardiovascular Translational Research | 2018 |
|
Epicardial Yap/Taz Orchestrate an Immune Suppressive Response following MI
Vimal Ramjee, Deqiang Li, Lauren Manderfield, Feiyan Liu, Kurt Engleka, Haig Aghajanian, Christopher B. Rodell, Wen Lu, Vivienne Ho, Tao Wang, Li Li, Anamika Singh, Dasan Cibi, Jason Burdick, Manvendra Singh, Rajan Jain, Jonathan A. Epstein |
Journal of Clinical Investigation | 2017 |
|
Redirecting cardiac growth mechanisms for therapeutic regeneration
Ravi Karra, Kenneth Poss |
Journal of Clinical Investigation | 2017 |
|
Pediatric and Adult Dilated Cardiomyopathy Represent Distinct Pathological Entities
Meghna Patel, Jayham Mohan, Caralin Schneider, Geetika Bajpai, Enkhsaikhan purevjav, Charles Canter, Jeffrey Towbin, Andrea Bredemeyer, Kory Lavine |
JCI Insight | 2017 |
|
A CCR2+ myeloid cell niche required for pancreatic β cell growth
Kristin Mussar, Stephanie Pardike, Tobias Hohl, Gary Hardiman, Vincenzo Cirulli, Laura Crisa |
JCI Insight | 2017 |
|
Myocardial aging as a T-cell–mediated phenomenon
GC Ramos, A Berg, V Nunes-Silva, J Weirather, L Peters, M Burkard, M Friedrich, J Pinnecker, M Abeßer, KG Heinze, K Schuh, N Beyersdorf, T Kerkau, J Demengeot, S Frantz, U Hofmann |
Proceedings of the National Academy of Sciences | 2017 |
|
Cardiac resident macrophages are involved in hypoxia-induced postnatal cardiomyocyte proliferation
B Liu, HG Zhang, Y Zhu, YH Jiang, GP Luo, FQ Tang, Z Jian, YB Xiao |
Molecular medicine reports | 2017 |
|
Loss of Macrophage Wnt Secretion Improves Remodeling and Function After Myocardial Infarction in Mice
D Palevski, LP LevinKotler, D Kain, N NaftaliShani, N Landa, T BenMordechai, T Konfino, R Holbova, N Molotski, R RosinArbesfeld, RA Lang, J Leor |
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease | 2017 |
|
Recruited Monocytes and Type 2 Immunity Promote Lung Regeneration following Pneumonectomy
AJ Lechner, IH Driver, J Lee, CM Conroy, A Nagle, RM Locksley, JR Rock |
Cell Stem Cell | 2017 |
|
Using biomaterials to rewire the process of wound repair
A Stejskalová, BD Almquist |
Biomaterials Science | 2017 |
|
Harnessing the early post-injury inflammatory responses for cardiac regeneration
B Cheng, HC Chen, IW Chou, TW Tang, PC Hsieh |
Journal of Biomedical Science | 2017 |
|
Possible Muscle Repair in the Human Cardiovascular System
L Sommese, A Zullo, C Schiano, FP Mancini, C Napoli |
Stem Cell Reviews and Reports | 2017 |
|
Pathophysiology and therapeutic potential of cardiac fibrosis
H Hara, N Takeda, I Komuro |
Inflammation and Regeneration | 2017 |
|
Efferocytosis and Outside-In Signaling by Cardiac Phagocytes. Links to Repair, Cellular Programming, and Intercellular Crosstalk in Heart
M DeBerge, S Zhang, K Glinton, L Grigoryeva, I Hussein, E Vorovich, K Ho, X Luo, EB Thorp |
Frontiers in immunology | 2017 |
|
Macrophages are necessary for epimorphic regeneration in African spiny mice
J Simkin, TR Gawriluk, JC Gensel, AW Seifert |
eLife | 2017 |
|
The transcription factor GATA4 promotes myocardial regeneration in neonatal mice
MM Mohammadi, B Kattih, A Grund, N Froese, M KorfKlingebiel, A Gigina, U Schrameck, C Rudat, Q Liang, A Kispert, KC Wollert, J Bauersachs, J Heineke |
EMBO Molecular Medicine | 2017 |
|
Cardiac Regeneration: Lessons From Development
FX Galdos, Y Guo, SL Paige, NJ VanDusen, SM Wu, WT Pu |
Circulation research | 2017 |
|
Ablation of periostin inhibits post-infarction myocardial regeneration in neonatal mice mediated by the phosphatidylinositol 3 kinase/glycogen synthase kinase 3β/cyclin D1 signalling pathway
Z Chen, J Xie, H Hao, H Lin, L Wang, Y Zhang, L Chen, S Cao, X Huang, W Liao, J Bin, Y Liao |
Cardiovascular Research | 2017 |
|
Approaches to augment vascularisation and regeneration of the adult heart via the reactivated epicardium
OJ Duffey, N Smart |
Global Cardiology Science and Practice | 2017 |
|
Exosomal MicroRNA Transfer Into Macrophages Mediates Cellular PostconditioningClinical Perspective
G Couto, R Gallet, L Cambier, E Jaghatspanyan, N Makkar, JF Dawkins, BP Berman, E Marbán |
Circulation | 2017 |
|
Is Cardioprotection Dead?
DJ Lefer, E Marbán |
Circulation | 2017 |
|
Immunomodulation-accelerated neuronal regeneration following selective rod photoreceptor cell ablation in the zebrafish retina
DT White, S Sengupta, MT Saxena, Q Xu, J Hanes, D Ding, H Ji, JS Mumm |
Proceedings of the National Academy of Sciences | 2017 |
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Mechanisms of Cardiomyocyte Proliferation and Differentiation in Development and Regeneration
JW Yester, B Kühn |
Current Cardiology Reports | 2017 |
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Learning from Mother Nature: Innovative Tools to Boost Endogenous Repair of Critical or Difficult-to-Heal Large Tissue Defects
R Cancedda, S Bollini, F Descalzi, M Mastrogiacomo, R Tasso |
Frontiers in Bioengineering and Biotechnology | 2017 |
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Cardiac regeneration strategies: Staying young at heart
E Tzahor, KD Poss |
Science | 2017 |
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Reciprocal analyses in zebrafish and medaka reveal that harnessing the immune response promotes cardiac regeneration
SL Lai, R Marín-Juez, PL Moura, C Kuenne, JK Lai, AT Tsedeke, S Guenther, M Looso, DY Stainier |
eLife | 2017 |
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Heart regeneration in the salamander relies on macrophage-mediated control of fibroblast activation and the extracellular landscape
JW Godwin, R Debuque, E Salimova, NA Rosenthal |
npj Regenerative Medicine | 2017 |
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Heart regeneration and the cardiomyocyte cell cycle
M Hesse, A Welz, BK Fleischmann |
Pflügers Archiv - European Journal of Physiology | 2017 |
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Paying the Toll in Nuclear Reprogramming
CL PhD, F Himmati, NS PhD |
Frontiers in Cell and Developmental Biology | 2017 |
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ZNF281 enhances cardiac reprogramming by modulating cardiac and inflammatory gene expression
H Zhou, MG Morales, H Hashimoto, ME Dickson, K Song, W Ye, MS Kim, H Niederstrasser, Z Wang, B Chen, BA Posner, R Bassel-Duby, EN Olson |
Genes & development | 2017 |
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A change of heart: a transforming view of cardiac function
AR Pinto |
npj Regenerative Medicine | 2017 |
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Early treatment with Resolvin E1 facilitates myocardial recovery from ischaemia in mice: Early therapy with RvE1 improves cardiac recovery after MI
G Liu, Q Liu, Y Shen, D Kong, Y Gong, B Tao, G Chen, S Guo, J Li, S Zuo, Y Yu, H Yin, L Zhang, B Zhou, CD Funk, J Zhang, Y Yu |
British Journal of Pharmacology | 2017 |
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Leukocyte diversity in resolving and nonresolving mechanisms of cardiac remodeling
B Tourki, G Halade |
The FASEB Journal | 2017 |
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Multicellular Transcriptional Analysis of Mammalian Heart Regeneration
GA Quaife-Ryan, CB Sim, M Ziemann, A Kaspi, H Rafehi, M Ramialison, A El-Osta, JE Hudson, ER Porrello |
Circulation | 2017 |
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SIRT1 regulates macrophage self‐renewal
F Imperatore, J Maurizio, SV Aguilar, CJ Busch, J Favret, E KowenzLeutz, W Cathou, R Gentek, P Perrin, A Leutz, C Berruyer, MH Sieweke |
The EMBO Journal | 2017 |
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Cardiac Macrophages, Reactive Oxygen Species, and Development of Left Ventricular Dysfunction ∗
Y Wang, S Epelman |
JACC: Basic to Translational Science | 2017 |
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Hypoxia-induced myocardial regeneration
W Kimura, Y Nakada, HA Sadek |
Journal of applied physiology | 2017 |
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Nephron progenitor cell death elicits a limited compensatory response associated with interstitial expansion in the neonatal kidney
SD Muthukrishnan, S Ryzhov, M Karolak, L Oxburgh |
Disease models & mechanisms | 2017 |
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Resident Macrophages: Near and Dear to Your Heart.
Munshi NV |
Cell | 2017 |
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MicroRNA-155 facilitates skeletal muscle regeneration by balancing pro- and anti-inflammatory macrophages
M Nie, J Liu, Q Yang, HY Seok, X Hu, ZL Deng, DZ Wang |
Cell Death and Disease | 2016 |
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The advantageous role of annexin A1 in cardiovascular disease
RJ de Jong, G Leoni, M Drechsler, O Soehnlein |
Cell adhesion & migration | 2016 |
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Striated muscle function, regeneration, and repair
IY Shadrin, A Khodabukus, N Bursac |
Cellular and Molecular Life Sciences | 2016 |
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Cardiomyocyte proliferation in zebrafish and mammals: lessons for human disease
G Matrone, CS Tucker, MA Denvir |
Cellular and Molecular Life Sciences | 2016 |
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Preserved Nephrogenesis Following Partial Nephrectomy in Early Neonates
Y Kirita, D Kami, R Ishida, T Adachi, K Tamagaki, S Matoba, T Kusaba, S Gojo |
Scientific Reports | 2016 |
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Macrophages in Tissue Repair, Regeneration, and Fibrosis
TA Wynn, KM Vannella |
Immunity | 2016 |
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Proliferation and Recruitment Contribute to Myocardial Macrophage Expansion in Chronic Heart FailureNovelty and Significance
HB Sager, M Hulsmans, KJ Lavine, MB Moreira, T Heidt, G Courties, Y Sun, Y Iwamoto, B Tricot, OF Khan, JE Dahlman, A Borodovsky, K Fitzgerald, DG Anderson, R Weissleder, P Libby, FK Swirski, M Nahrendorf |
Circulation research | 2016 |
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Immune Modulation of Cardiac Repair and Regeneration: The Art of Mending Broken Hearts
I Zlatanova, C Pinto, JS Silvestre |
Frontiers in Cardiovascular Medicine | 2016 |
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Development and Function of Arterial and Cardiac Macrophages
FK Swirski, CS Robbins, M Nahrendorf |
Trends in Immunology | 2016 |
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Cardiac fibrosis in myocardial infarction—from repair and remodeling to regeneration
V Talman, H Ruskoaho |
Cell and Tissue Research | 2016 |
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Resolvin E1 Reverses Experimental Periodontitis and Dysbiosis
CT Lee, R Teles, A Kantarci, T Chen, J McCafferty, JR Starr, LC Brito, BJ Paster, TE van Dyke |
Journal of immunology (Baltimore, Md. : 1950) | 2016 |
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Epicardium is required for cardiac seeding by yolk sac macrophages, precursors of resident macrophages of the adult heart
SM Stevens, A Gise, N VanDusen, B Zhou, WT Pu |
Developmental Biology | 2016 |
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Macrophages in the Remodeling Failing Heart
B Chen, NG Frangogiannis |
Circulation research | 2016 |
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Evidence for Mechanisms Underlying the Functional Benefits of a Myocardial Matrix Hydrogel for Post-MI Treatment
JW Wassenaar, R Gaetani, JJ Garcia, RL Braden, CG Luo, D Huang, AN DeMaria, JH Omens, KL Christman |
Journal of the American College of Cardiology | 2016 |
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Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice
G Monnerat, ML Alarcón, LR Vasconcellos, C Hochman-Mendez, G Brasil, RA Bassani, O Casis, D Malan, LH Travassos, M Sepúlveda, JI Burgos, M Vila-Petroff, FF Dutra, MT Bozza, CN Paiva, AB Carvalho, A Bonomo, BK Fleischmann, AC de Carvalho, E Medei |
Nature Communications | 2016 |
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Extracellular HSP60 triggers tissue regeneration and wound healing by regulating inflammation and cell proliferation
W Pei, K Tanaka, SC Huang, L Xu, B Liu, J Sinclair, J Idol, GK Varshney, H Huang, S Lin, RB Nussenblatt, R Mori, SM Burgess |
npj Regenerative Medicine | 2016 |
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Building and re-building the heart by cardiomyocyte proliferation
MJ Foglia, KD Poss |
Development (Cambridge, England) | 2016 |
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The Biological Basis for Cardiac Repair After Myocardial Infarction: From Inflammation to Fibrosis
SD Prabhu, NG Frangogiannis |
Circulation research | 2016 |
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Tissue Engineering Strategies for Myocardial Regeneration: Acellular Versus Cellular Scaffolds?
M Domenech, L Polo-Corrales, JE Ramirez-Vick, DO Freytes |
Tissue Engineering Part B: Reviews | 2016 |
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Cell migration during heart regeneration in zebrafish: Cell Migration During Heart Regeneration
N Tahara, M Brush, Y Kawakami |
Developmental Dynamics | 2016 |
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Recent advancements in understanding endogenous heart regeneration—insights from adult zebrafish and neonatal mice
N Rubin, MR Harrison, M Krainock, R Kim, CL Lien |
Seminars in Cell & Developmental Biology | 2016 |
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Origins of cardiac fibroblasts
T Moore-Morris, P Cattaneo, M Puceat, SM Evans |
Journal of Molecular and Cellular Cardiology | 2016 |
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Distinct effects of inflammation on preconditioning and regeneration of the adult zebrafish heart
AS Charles, T Bise, F Baier, J Marro, A Jaźwińska |
Open Biology | 2016 |
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Bmi1 + cardiac progenitor cells contribute to myocardial repair following acute injury
I Valiente-Alandi, C Albo-Castellanos, D Herrero, I Sanchez, A Bernad |
Stem Cell Research & Therapy | 2016 |
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Mechanisms of Cardiac Regeneration
A Uygur, RT Lee |
Developmental Cell | 2016 |
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Evolution, comparative biology and ontogeny of vertebrate heart regeneration
CJ Vivien, JE Hudson, ER Porrello |
npj Regenerative Medicine | 2016 |
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Chasing the recipe for a pro-regenerative immune system
JW Godwin, AR Pinto, NA Rosenthal |
Seminars in Cell & Developmental Biology | 2016 |
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Changes in gene methylation patterns in neonatal murine hearts: Implications for the regenerative potential
B Górnikiewicz, A Ronowicz, M Krzemiński, P Sachadyn |
BMC Genomics | 2016 |
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Primitive Embryonic Macrophages are Required for Coronary Development and MaturationNovelty and Significance
J Leid, J Carrelha, H Boukarabila, S Epelman, SE Jacobsen, KJ Lavine |
Circulation research | 2016 |
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Emerging roles for macrophages in cardiac injury: cytoprotection, repair, and regeneration
Nikolaos Frangogiannis |
Journal of Clinical Investigation | 2015 |
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Macrophages mediate cardioprotective cellular postconditioning in acute myocardial infarction
Geoffrey de Couto, Wenxie Liu, Eleni Tseliou, Baiming Sun, Nupur Makkar, Hideaki Kanazawa, Moshe Arditi, Eduardo Marbán |
Journal of Clinical Investigation | 2015 |
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Targeting Interleukin-1β Reduces Leukocyte Production After Acute Myocardial Infarction
HB Sager, T Heidt, M Hulsmans, P Dutta, G Courties, M Sebas, GR Wojtkiewicz, B Tricot, Y Iwamoto, Y Sun, R Weissleder, P Libby, FK Swirski, M Nahrendorf |
Circulation | 2015 |
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Deriving a cardiac ageing signature to reveal MMP-9-dependent inflammatory signalling in senescence
Y Ma, YA Chiao, R Clark, ER Flynn, A Yabluchanskiy, O Ghasemi, F Zouein, ML Lindsey, YF Jin |
Cardiovascular Research | 2015 |
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Beyond vascular inflammation—recent advances in understanding atherosclerosis
D Wolf, A Zirlik, K Ley |
Cellular and Molecular Life Sciences | 2015 |
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Role of innate and adaptive immune mechanisms in cardiac injury and repair
S Epelman, PP Liu, DL Mann |
Nature Reviews Immunology | 2015 |
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Cardiac regeneration: epicardial mediated repair
T Kennedy-Lydon, N Rosenthal |
Proceedings of the Royal Society B: Biological Sciences | 2015 |
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The Evolution of the Stem Cell Theory for Heart Failure
JS Silvestre, P Menasché |
EBioMedicine | 2015 |
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Engineering control into medicine
DJ Stone, LA Celi, M Csete |
Journal of Critical Care | 2015 |
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Inflammation in cardiac injury, repair and regeneration:
NG Frangogiannis |
Current Opinion in Cardiology | 2015 |
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ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation
G D’Uva, A Aharonov, M Lauriola, D Kain, Y Yahalom-Ronen, S Carvalho, K Weisinger, E Bassat, D Rajchman, O Yifa, M Lysenko, T Konfino, J Hegesh, O Brenner, M Neeman, Y Yarden, J Leor, R Sarig, RP Harvey, E Tzahor |
Nature Cell Biology | 2015 |
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Myocardial infarction: a critical role of macrophages in cardiac remodeling
T Weinberger, C Schulz |
Frontiers in physiology | 2015 |
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Monocytes in Myocardial Infarction
P Dutta, M Nahrendorf |
Arteriosclerosis, thrombosis, and vascular biology | 2015 |
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Inflammation as a therapeutic target in myocardial infarction: learning from past failures to meet future challenges
A Saxena, I Russo, NG Frangogiannis |
Translational Research | 2015 |
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The mammalian blastema: regeneration at our fingertips: Regeneration at our Fingertips
J Simkin, MC Sammarco, LA Dawson, PP Schanes, L Yu, K Muneoka |
Regeneration | 2015 |
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Nerves Regulate Cardiomyocyte Proliferation and Heart Regeneration
AI Mahmoud, CC O’Meara, M Gemberling, L Zhao, DM Bryant, R Zheng, JB Gannon, L Cai, WY Choi, GF Egnaczyk, CE Burns, CG Burns, CA MacRae, KD Poss, RT Lee |
Developmental Cell | 2015 |
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Acute inflammation stimulates a regenerative response in the neonatal mouse heart
C Han, Y Nie, H Lian, R Liu, F He, H Huang, S Hu |
Cell Research | 2015 |
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Recent Developments in Heart Failure
S Dassanayaka, SP Jones |
Circulation research | 2015 |
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Telomerase Is Essential for Zebrafish Heart Regeneration
D Bednarek, JM González-Rosa, G Guzmán-Martínez, Ó Gutiérrez-Gutiérrez, T Aguado, C Sánchez-Ferrer, IJ Marques, M Galardi-Castilla, I de Diego, MJ Gómez, A Cortés, A Zapata, LJ Jiménez-Borreguero, N Mercader, I Flores |
Cell Reports | 2015 |
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Caspase 3 cleavage of Pax7 inhibits self-renewal of satellite cells
SA Dick, NC Chang, NA Dumont, RA Bell, C Putinski, Y Kawabe, DW Litchfield, MA Rudnicki, LA Megeney |
Proceedings of the National Academy of Sciences | 2015 |
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Spatially localized recruitment of anti-inflammatory monocytes by SDF-1α-releasing hydrogels enhances microvascular network remodeling
JR Krieger, ME Ogle, J McFaline-Figueroa, CE Segar, JS Temenoff, EA Botchwey |
Biomaterials | 2015 |
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Myocardial NF-κB activation is essential for zebrafish heart regeneration
R Karra, AK Knecht, K Kikuchi, KD Poss |
Proceedings of the National Academy of Sciences | 2015 |
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The Nervous Heart: Role of Sympathetic Reinnervation in Cardiac Regeneration
VN Garikipati, SK Verma, R Kishore |
Circulation research | 2015 |
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Dynamic microRNA-101a and Fosab expression controls zebrafish heart regeneration
M Beauchemin, A Smith, VP Yin |
Development (Cambridge, England) | 2015 |
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Fanning the flames to regenerate the heart
Paul Riley |
Journal of Clinical Investigation | 2014 |
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Klhl40 Deficiency Destabilizes Thin Filament Proteins and Causes Nemaline Myopathy
Ankit Garg, Jason O'Rourke, Chengzu Long, Jonathan Doering, Gianina Ravenscroft, Svetlana Bezprozvannaya, Benjamin Nelson, Nadine Beetz, Lin Li, She Chen, Nigel G. Laing, Robert Grange, Rhonda Bassel-Duby, Eric N. Olson |
Journal of Clinical Investigation | 2014 |
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An emerging consensus on cardiac regeneration
JH van Berlo, JD Molkentin |
Nature Medicine | 2014 |
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A neonatal blueprint for cardiac regeneration
ER Porrello, EN Olson |
Stem Cell Research | 2014 |
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Regulation and consequences of monocytosis
P Dutta, M Nahrendorf |
Immunological Reviews | 2014 |
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Cardiac-Specific YAP Activation Improves Cardiac Function and Survival in an Experimental Murine MI Model
Z Lin, A Gise, P Zhou, F Gu, Q Ma, J Jiang, AL Yau, JN Buck, KA Gouin, PR van Gorp, B Zhou, J Chen, JG Seidman, DZ Wang, WT Pu |
Circulation research | 2014 |
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Origin and Functions of Tissue Macrophages
S Epelman, KJ Lavine, GJ Randolph |
Immunity | 2014 |
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Immune Modulation of Stem Cells and Regeneration
AB Aurora, EN Olson |
Cell Stem Cell | 2014 |
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Distinct macrophage lineages contribute to disparate patterns of cardiac recovery and remodeling in the neonatal and adult heart
KJ Lavine, S Epelman, K Uchida, KJ Weber, CG Nichols, JD Schilling, DM Ornitz, GJ Randolph, DL Mann |
2014 | |
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Telocytes and putative stem cells in ageing human heart
LM Popescu, A Curici, E Wang, H Zhang, S Hu, M Gherghiceanu |
Journal of Cellular and Molecular Medicine | 2014 |
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Progressive replacement of embryo-derived cardiac macrophages with age
K Molawi, Y Wolf, PK Kandalla, J Favret, N Hagemeyer, K Frenzel, AR Pinto, K Klapproth, S Henri, B Malissen, HR Rodewald, NA Rosenthal, M Bajenoff, M Prinz, S Jung, MH Sieweke |
Journal of Experimental Medicine | 2014 |
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Neonatal Heart Regeneration: Mounting Support and Need for Technical Standards
S Sen, HA Sadek |
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease | 2014 |
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The Type of Injury Dictates the Mode of Repair in Neonatal and Adult Heart
T Konfino, N Landa, T Ben-Mordechai, J Leor |
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease | 2014 |
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Hippo in the Path to Heart Repair
JB Papizan, EN Olson |
Circulation research | 2014 |
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