JCI - Citations to The role of αv integrins during angiogenesis: insights into potential mechanisms of action and clinical development

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The role of αv integrins during angiogenesis: insights into potential mechanisms of action and clinical development

Brian P. Eliceiri, David A. Cheresh

Brian P. Eliceiri, David A. Cheresh

Published May 1, 1999
Citation Information: J Clin Invest. 1999;103(9):1227-1230. https://doi.org/10.1172/JCI6869.

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TNFα Accelerates Monocyte to Endothelial Transdifferentiation in Tumors by the Induction of Integrin α 5 Expression and Adhesion to Fibronectin B Li, A Pozzi, PP Young	Molecular cancer research : MCR	2011
Two cDNAs coding for the porcine CD51 (αv) integrin subunit: Cloning, expression analysis, adhesion assays and chromosomal localization N Yubero, Á Jiménez-Marín, M Barbancho, JJ Garrido	Gene	2011
Advances in Immunology E Pinaud, M Marquet, R Fiancette, S Péron, C Vincent-Fabert, Y Denizot, M Cogné	Advances in Immunology Volume 110	2011
Selected aspects of angiogensis in haematological malignancies P Sujka-Kordowska, A Malińska, M Zabel	Advances in Cell Biology	2011
Integrin targeted delivery of radiotherapeutics Z Liu, F Wang, X Chen	Theranostics	2011
Integrin imaging to evaluate treatment response M Morrison, A Cuthbertson	Theranostics	2011
PET imaging of early response to the tyrosine kinase inhibitor ZD4190 M Yang, H Gao, Y Yan, X Sun, K Chen, Q Quan, L Lang, D Kiesewetter, G Niu, X Chen	European Journal of Nuclear Medicine and Molecular Imaging	2011
Cilengitide in patients with recurrent glioblastoma: the results of NABTC 03-02, a phase II trial with measures of treatment delivery MR Gilbert, J Kuhn, KR Lamborn, F Lieberman, PY Wen, M Mehta, T Cloughesy, AB Lassman, LM DeAngelis, S Chang, M Prados	Journal of Neuro-Oncology	2011
Fibronectin–hyaluronic acid composite hydrogels for three-dimensional endothelial cell culture SK Seidlits, CT Drinnan, RR Petersen, JB Shear, LJ Suggs, CE Schmidt	Acta Biomaterialia	2011
Bioconjugated PLGA-4-arm-PEG branched polymeric nanoparticles as novel tumor targeting carriers H Ding, KT Yong, I Roy, R Hu, F Wu, L Zhao, WC Law, W Zhao, W Ji, L Liu, EJ Bergey, PN Prasad	Nanotechnology	2011
Investigation of the Best Conditions to Obtain c(RGDfK) Peptide on Solid Phase AD Gatto, M Simone, I Paola, M Saviano, L Zaccaro	International Journal of Peptide Research and Therapeutics	2011
The role of β3-integrins in tumor angiogenesis: context is everything SD Robinson, KM Hodivala-Dilke	Current Opinion in Cell Biology	2011
Annual Reports in Medicinal Chemistry JJ Liu, TW Lee	Annual Reports in Medicinal Chemistry Volume 46	2011
Advances in Cancer Research M Lemaire, S Deleu, ED Bruyne, EV Valckenborgh, E Menu, K Vanderkerken	Advances in Cancer Research Volume 110	2011
Interleukin-17A induction of angiogenesis, cell migration, and cytoskeletal rearrangement EM Moran, M Connolly, W Gao, J McCormick, U Fearon, DJ Veale	Arthritis & Rheumatism	2011
Focal adhesion kinase and its signaling pathways in cell migration and angiogenesis X Zhao, JL Guan	Advanced Drug Delivery Reviews	2011
Next Generation of Electrosprayed Fibers for Tissue Regeneration JK Hong, SV Madihally	Tissue engineering. Part B, Reviews	2011
Functional analysis of a recombinant PIII-SVMP, GST-acocostatin; an apoptotic inducer of HUVEC and HeLa, but not SK-Mel-28 cells T Teklemariam, AI Seoane, CJ Ramos, EE Sanchez, SE Lucena, JC Perez, SA Mandal, JG Soto	Toxicon : official journal of the International Society on Toxinology	2011
Recurrent Glioblastoma: A Fresh Look at Current Therapies and Emerging Novel Approaches MR Gilbert	Seminars in Oncology	2011
Increased matrix synthesis by fibroblasts with decreased proliferation on synthetic chitosan-gelatin porous structures P Iyer, KJ Walker, SV Madihally	Biotechnology and Bioengineering	2011
Engagement of αIIbβ3 (GPIIb/IIIa) with ανβ3 integrin mediates interaction of melanoma cells with platelets: a connection to hematogenous metastasis AS Lonsdorf, BF Krämer, M Fahrleitner, T Schönberger, S Gnerlich, S Ring, S Gehring, SW Schneider, MJ Kruhlak, SG Meuth, B Nieswandt, M Gawaz, AH Enk, HF Langer	The Journal of biological chemistry	2011
Engagement of αIIbβ3 (GPIIb/IIIa) with ανβ3 Integrin Mediates Interaction of Melanoma Cells with Platelets AS Lonsdorf, BF Krämer, M Fahrleitner, T Schönberger, S Gnerlich, S Ring, S Gehring, SW Schneider, MJ Kruhlak, SG Meuth, B Nieswandt, M Gawaz, AH Enk, HF Langer	The Journal of biological chemistry	2011
Kidney Cancer PN Lara, E Jonasch	Kidney Cancer	2011
Clinical and pharmacologic evaluation of two dose levels of intetumumab (CNTO 95) in patients with melanoma or angiosarcoma SJ ODay, AC Pavlick, MR Albertini, O Hamid, H Schalch, Z Lang, J Ling, M Mata, M Reddy, B Foster	Investigational New Drugs	2011
Tumor vasculature as target for therapeutic intervention MH Fens, G Storm, RM Schiffelers	Expert Opinion on Investigational Drugs	2010
Molecular Mediators of Angiogenesis AA Ucuzian, AA Gassman, AT East, HP Greisler	Journal of Burn Care & Research	2010
Focal adhesion kinase: a prominent determinant in breast cancer initiation, progression and metastasis M Luo, JL Guan	Cancer Letters	2010
Burger's Medicinal Chemistry and Drug Discovery S Bruno, L Ronda, S Faggiano, S Bettati, A Mozzarelli	Burger's Medicinal Chemistry and Drug Discovery	2010
αVβ3 integrin regulates macrophage inflammatory responses via PI3 kinase/Akt-dependent NF-κB activation AS Antonov, GN Antonova, DH Munn, N Mivechi, R Lucas, JD Catravas, AD Verin	Journal of Cellular Physiology	2010
Angiogenesis TH Adair, JP Montani	Colloquium Series on Integrated Systems Physiology: From Molecule to Function	2010
Multiplexed Five-Color Molecular Imaging of Cancer Cells and Tumor Tissues with Carbon Nanotube Raman Tags in the Near-Infrared Z Liu, S Tabakman, S Sherlock, X Li, Z Chen, K Jiang, S Fan, H Dai	Nano research	2010
Narrow-band imaging endoscopy to assess mucosal angiogenesis in inflammatory bowel disease: a pilot study S Danese, G Fiorino, E Angelucci, S Vetrano, N Pagano, G Rando, A Spinelli, A Malesci, A Repici	World journal of gastroenterology : WJG	2010
Specific Targeting of Human Integrin αvβ3 with 111In-Labeled Abegrin™ in Nude Mouse Models Z Liu, B Jia, H Zhao, X Chen, F Wang	Molecular Imaging and Biology	2010
Improving bacterial cellulose for blood vessel replacement: Functionalization with a chimeric protein containing a cellulose-binding module and an adhesion peptide FK Andrade, R Costa, L Domingues, R Soares, M Gama	Acta Biomaterialia	2010
The immunology of corneal xenotransplantation: a review of the literature H Hara, DK Cooper	Xenotransplantation	2010
A randomized phase 2 study of etaracizumab, a monoclonal antibody against integrin αvβ3, ± dacarbazine in patients with stage IV metastatic melanoma P Hersey, J Sosman, S O'Day, J Richards, A Bedikian, R Gonzalez, W Sharfman, R Weber, T Logan, M Buzoianu, L Hammershaimb, JM Kirkwood	Cancer	2010
Artificial RGD receptor molecules T Gersthagen, C Schmuck, T Schrader	Supramolecular Chemistry	2010
Optical Imaging of Integrin αv β3 Expression with Near-Infrared Fluorescent RGD Dimer with Tetra(ethylene glycol) Linkers Z Liu, S Liu, G Niu, F Wang, S Liu, X Chen	Molecular imaging	2010
Small molecules for bone diseases K Masuya, N Teno	Expert Opinion on Therapeutic Patents	2010
Transdominant regulation of integrin function: Mechanisms of crosstalk AM Gonzalez, R Bhattacharya, GW deHart, JC Jones	Cellular Signalling	2010
Optical Imaging of Integrin α v β 3 Expression with Near-Infrared Fluorescent RGD Dimer with Tetra(ethylene glycol) Linkers Z Liu, S Liu, G Niu, F Wang, S Liu, X Chen	Molecular imaging	2010
Therapeutic Angiogenesis for Vascular Diseases M Slevin		2010
Anticancer strategies involving the vasculature VL Heath, R Bicknell	Nature Reviews Clinical Oncology	2009
Imaging myocardial angiogenesis JJ Wykrzykowska, TD Henry, JR Lesser, RS Schwartz	Nature Reviews Cardiology	2009
(64)Cu-labeled CB-TE2A and diamsar-conjugated RGD peptide analogs for targeting angiogenesis: comparison of their biological activity L Wei, Y Ye, TJ Wadas, JS Lewis, MJ Welch, S Achilefu, CJ Anderson	Nuclear Medicine and Biology	2009
Single and combined effects of alphavbeta3- and alpha5beta1-integrins on capillary tube formation in a human fibrinous matrix N Laurens, MA Engelse, C Jungerius, CW Löwik, VW van Hinsbergh, P Koolwijk	Angiogenesis	2009
Bioartificial matrices for therapeutic vascularization EA Phelps, N Landázuri, PM Thulé, WR Taylor, AJ García	Proceedings of the National Academy of Sciences	2009
Sphingosine kinase-1 associates with integrin {alpha}V{beta}3 to mediate endothelial cell survival JR Gamble, WY Sun, X Li, CN Hahn, SM Pitson, MA Vadas, CS Bonder	The American Journal of Pathology	2009
A novel peptide (GX1) homing to gastric cancer vasculature inhibits angiogenesis and cooperates with TNF alpha in anti-tumor therapy B Chen, S Cao, Y Zhang, X Wang, J Liu, X Hui, Y Wan, W Du, L Wang, K Wu, D Fan	BMC cell biology	2009
Adenovirus dodecahedron, as a drug delivery vector M Zochowska, A Paca, G Schoehn, JP Andrieu, J Chroboczek, B Dublet, E Szolajska	PloS one	2009
Intravascularly administered RGD-displaying measles viruses bind to and infect neovessel endothelial cells in vivo HT Ong, TR Trejo, LD Pham, AL Oberg, SJ Russell, KW Peng	Molecular Therapy	2009
Instant immunity through chemically programmable vaccination and covalent self-assembly M Popkov, B Gonzalez, SC Sinha, CF 3rd	Proceedings of the National Academy of Sciences	2009
Noninvasive imaging of tumor integrin expression using 18F-labeled RGD dimer peptide with PEG4 linkers Z Liu, S Liu, F Wang, S Liu, X Chen	European Journal of Nuclear Medicine and Molecular Imaging	2009
68Ga-labeled cyclic RGD dimers with Gly3 and PEG4 linkers: promising agents for tumor integrin αvβ3 PET imaging Z Liu, G Niu, J Shi, S Liu, F Wang, S Liu, X Chen	European Journal of Nuclear Medicine and Molecular Imaging	2009
The role of cell adhesion pathways in angiogenesis AR Ramjaun, K Hodivala-Dilke	The International Journal of Biochemistry & Cell Biology	2009
DNAzymes to mouse β1 integrin mRNA in vivo: targeting the tumor vasculature and retarding cancer growth J Niewiarowska, I Sacewicz, M Wiktorska, T Wysocki, O Stasikowska, M Wagrowska-Danilewicz, CS Cierniewski	Cancer Gene Therapy	2009
Functional single-walled carbon nanotubes based on an integrin αvβ3monoclonal antibody for highly efficient cancer cell targeting Z Ou, B Wu, D Xing, F Zhou, H Wang, Y Tang	Nanotechnology	2009
Signal transduction by focal adhesion kinase in cancer J Zhao, JL Guan	Cancer and Metastasis Reviews	2009
In vivo Engineering of Tissues: Biological Considerations, Challenges, Strategies, and Future Directions VP Shastri	Advanced Materials	2009
MODELLING VASCULAR MORPHOGENESIS: CURRENT VIEWS ON BLOOD VESSELS DEVELOPMENT MÁ Herrero, Á Köhn, JM Pérez-Pomares	Mathematical Models and Methods in Applied Sciences	2009
Expression Order of Alpha-v and Beta-3 Integrin Subunits in the N -Methyl- N -Nitrosourea-Induced Rat Mammary Tumor Model R Rezaeipoor, EJ Chaney, AL Oldenburg, SA Boppart	Cancer Investigation	2009
Adenovirus Dodecahedron, as a Drug Delivery Vector M Zochowska, A Paca, G Schoehn, JP Andrieu, J Chroboczek, B Dublet, E Szolajska, GC Jagetia	PloS one	2009
Cell-Extracellular Matrix Interactions in Cancer R Zent, A Pozzi		2009
Ocular Inflammation in Cynomolgus Macaques Following Intravenous Administration of a Human Monoclonal Antibody PL Martin, PE Miller, M Mata, BJ Christian	International Journal of Toxicology	2009
Validation of PDGFRbeta and c-Src tyrosine kinases as tumor/vessel targets in patients with multiple myeloma: preclinical efficacy of the novel, orally available inhibitor dasatinib AM Coluccia, T Cirulli, P Neri, D Mangieri, MC Colanardi, A Gnoni, ND Renzo, F Dammacco, P Tassone, D Ribatti, C Gambacorti-Passerini, A Vacca	Blood	2008
Constitutive expression of IL-12R beta 2 on human multiple myeloma cells delineates a novel therapeutic target I Airoldi, C Cocco, N Giuliani, M Ferrarini, S Colla, E Ognio, G Taverniti, ED Carlo, G Cutrona, V Perfetti, V Rizzoli, D Ribatti, V Pistoia	Blood	2008
The angiogenic response is dictated by beta3 integrin on bone marrow-derived cells W Feng, NP McCabe, GH Mahabeleshwar, PR Somanath, DR Phillips, TV Byzova	The Journal of Cell Biology	2008
Research Resource: Rapid Recruitment of Temporally Distinct Vascular Gene Sets by Estrogen KK Schnoes, IZ Jaffe, L Iyer, A Dabreo, M Aronovitz, B Newfell, U Hansen, G Rosano, ME Mendelsohn	Molecular Endocrinology	2008
H-Ras Regulates Angiogenesis and Vascular Permeability by Activation of Distinct Downstream Effectors D Serban, J Leng, D Cheresh	Circulation research	2008
Angiogenic endothelium shows lactadherin-dependent phagocytosis of aged erythrocytes and apoptotic cells MH Fens, E Mastrobattista, AM de Graaff, FM Flesch, A Ultee, JT Rasmussen, G Molema, G Storm, RM Schiffelers	Blood	2008
Role of the αv-integrin subunit in cell proliferation, apoptosis and tumor metastasis of laryngeal and hypopharyngeal squamous cell carcinomas: a clinical and in vitro investigation JG Lu, YN Sun, C Wang, DJ Jin, M Liu	European Archives of Oto-Rhino-Laryngology	2008
Pharmacokinetics of TDP223206 following intravenous and oral administration to intact rats and intravenous administration to bile duct-cannulated rats Y Chen, D Cheng, JJ Marugan, C Manthey, B Tomczuk, N Huebert	Biopharmaceutics & Drug Disposition	2008
Pro-inflammatory secretory phospholipase A2 type IIA binds to integrins alphavbeta3 and alpha4beta1 and induces proliferation of monocytic cells in an integrin-dependent manner J Saegusa, N Akakura, CY Wu, C Hoogland, Z Ma, KS Lam, FT Liu, YK Takada, Y Takada	The Journal of biological chemistry	2008
Molecular Imaging JC Wu	Journal of the American College of Cardiology	2008
Oxidized low density lipoprotein impairs endothelial progenitor cell function by downregulation of E-selectin and integrin αvβ5 SD Santo, N Diehm, J Ortmann, J Völzmann, Z Yang, HH Keo, I Baumgartner, C Kalka	Biochemical and Biophysical Research Communications	2008
Administering Plasmid DNA Encoding Tumor Vessel–anchored IFN-α for Localizing Gene Product Within or Into Tumors R Craig, J Cutrera, S Zhu, X Xia, YH Lee, S Li	Molecular Therapy	2008
In vivo gamma imaging of the secondary tumors of transplanted human fetal striatum neural stem cells-derived primary tumor cells Q He, Z Liu, B Jia, X Li, J Shi, J Zhang, F Lan, Z Yang, Y Liu, L Shen, F Wang	NeuroReport	2008
Application of Metal‐Free Triazole Formation in the Synthesis of Cyclic RGD–DTPA Conjugates SS van Berkel, AT Dirks, SA Meeuwissen, DL Pingen, OC Boerman, P Laverman, FL van Delft, JJ Cornelissen, FP Rutjes	ChemBioChem	2008
Determining glioma response to radiation therapy using recombinant peptides R Diaz, RJ Passarella, DE Hallahan	Expert Review of Anticancer Therapy	2008
A Potent Integrin Antagonist from a Small Library of Cyclic RGD Pentapeptide Mimics Including Benzyl-Substituted Azabicycloalkane Amino Acids D Arosio, L Belvisi, L Colombo, M Colombo, D Invernizzi, L Manzoni, D Potenza, M Serra, M Castorina, C Pisano, C Scolastico	ChemMedChem	2008
Antidepressant treatments regulate matrix metalloproteinases-2 and -9 (MMP-2/MMP-9) and tissue inhibitors of the metalloproteinases (TIMPS 1-4) in the adult rat hippocampus M Benekareddy, P Mehrotra, VA Kulkarni, P Ramakrishnan, BG Dias, VA Vaidya	Synapse	2008
Specific targeting of the vasculature of gastric cancer by a new tumor-homing peptide CGNSNPKSC X Hui, Y Han, S Liang, Z Liu, J Liu, L Hong, L Zhao, L He, S Cao, B Chen, K Yan, B Jin, N Chai, J Wang, K Wu, D Fan	Journal of Controlled Release	2008
Design and synthesis of cyclo[-Arg-Gly-Asp-Ψ(triazole)-Gly-Xaa-] peptide analogues by click chemistry Y Liu, L Zhang, J Wan, Y Li, Y Xu, Y Pan	Tetrahedron	2008
Breast Cancer: Prognosis, Treatment, and Prevention C Campagnoli, C Peris, P Pasanisi, F Berrino	Breast Cancer: Prognosis, Treatment, and Prevention	2008
Greenfield's Neuropathology Eighth Edition. 2 Volume Set and DVD R Sobel, GR Moore	Greenfield's Neuropathology Eighth Edition. 2 Volume Set and DVD	2008
Pro-inflammatory Secretory Phospholipase A2 Type IIA Binds to Integrins αvβ3 and α4β1 and Induces Proliferation of Monocytic Cells in an Integrin-dependent Manner J Saegusa, N Akakura, CY Wu, C Hoogland, Z Ma, KS Lam, FT Liu, YK Takada, Y Takada	The Journal of biological chemistry	2008
Structural Basis for the Interaction of iso DGR with the RGD-binding Site of αvβ3 Integrin A Spitaleri, S Mari, F Curnis, C Traversari, R Longhi, C Bordignon, A Corti, GP Rizzardi, G Musco	The Journal of biological chemistry	2008
DNA Micro-Array Gene Expression Profiling of Angiogenesis in Collagen Gel Culture M Akita, K Fujita	Clinical medicine. Cardiology	2008
Key role of α 1 β 1 -integrin in the activation of PI3-kinase-Akt by flow (shear stress) in resistance arteries L Loufrani, K Retailleau, A Bocquet, O Dumont, K Danker, H Louis, P Lacolley, D Henrion	American journal of physiology. Heart and circulatory physiology	2008
Selected Aspects of Cancer Progression: Metastasis, Apoptosis and Immune Response HE Kaiser, A Nasir		2008
Retinal and Choroidal Angiogenesis JS Penn		2008
Methods of Cancer Diagnosis, Therapy and Prognosis MA Hayat		2008
Use of a Novel Arg-Gly-Asp Radioligand, 18 F-AH111585, to Determine Changes in Tumor Vascularity After Antitumor Therapy MS Morrison, SA Ricketts, J Barnett, A Cuthbertson, J Tessier, SR Wedge	Journal of Nuclear Medicine	2008
Radiosynthesis and Biodistribution of Cyclic RGD Peptides Conjugated with Novel [ 18 F]Fluorinated Aldehyde-Containing Prosthetic Groups M Glaser, M Morrison, M Solbakken, J Arukwe, H Karlsen, U Wiggen, S Champion, GM Kindberg, A Cuthbertson	Bioconjugate Chemistry	2008
Anti-Inflammatory Effects of αv Integrin Antagonism in Acute Kidney Allograft Rejection J Bedke, E Kiss, CL Behnes, ZV Popovic, M Heuser, T Stojanovic, T Sijmonsma, P Huber, S Domhan, S Muschal, A Abdollahi, N Gretz, HJ Gröne	The American Journal of Pathology	2007
Targeted nanoparticle-based drug delivery and diagnosis DF Emerich, CG Thanos	Journal of Drug Targeting	2007
A novel αvβ3-blocking disintegrin containing the RGD motive, DisBa-01, inhibits bFGF-induced angiogenesis and melanoma metastasis OH Ramos, A Kauskot, MR Cominetti, I Bechyne, CL Pontes, F Chareyre, J Manent, R Vassy, M Giovannini, C Legrand, HS Selistre-de-Araujo, M Crépin, A Bonnefoy	Clinical & Experimental Metastasis	2007
Ocular neovascularization: Implication of endogenous angiogenic inhibitors and potential therapy SX Zhang, J Ma	Progress in Retinal and Eye Research	2007
The Cancer Handbook U Anand	The Cancer Handbook	2007
Pharmacogenomics and the Yin/Yang actions of ginseng: anti-tumor, angiomodulating and steroid-like activities of ginsenosides PY Yue, NK Mak, YK Cheng, KW Leung, TB Ng, DT Fan, HW Yeung, RN Wong	Chinese medicine	2007
alpha2beta1 integrin expression in the tumor microenvironment enhances tumor angiogenesis in a tumor cell-specific manner Z Zhang, NE Ramirez, TE Yankeelov, Z Li, LE Ford, Y Qi, A Pozzi, MM Zutter	Blood	2007
ITGAV polymorphism and disease susceptibility in a Japanese rheumatoid arthritis population N Iikuni, S Kobayashi, K Ikari, T Tomatsu, M Hara, H Yamanaka, N Kamatani, S Momohara	Arthritis Research & Therapy	2007
Targeting the Tumor Vasculature to Improve the Efficacy of Oncolytic Virus Therapy JH Rhim, G Tosato	JNCI Journal of the National Cancer Institute	2007
Novel agents in ovarian cancer D Matei	Expert Opinion on Investigational Drugs	2007
Angiostatin and integrin ?v?3 in the feline, bovine, canine, equine, porcine and murine retina and cornea JW Pearce, KS Janardhan, S Caldwell, B Singh	Veterinary Ophthalmology	2007
Mechanisms controlling human endothelial lumen formation and tube assembly in three-dimensional extracellular matrices GE Davis, W Koh, AN Stratman	Birth Defects Research Part C: Embryo Today: Reviews	2007
Abrogation of the interaction between osteopontin and αvβ3 integrin reduces tumor growth of human lung cancer cells in mice R Cui, F Takahashi, R Ohashi, T Gu, M Yoshioka, K Nishio, Y Ohe, S Tominaga, Y Takagi, S Sasaki, Y Fukuchi, K Takahashi	Lung Cancer	2007
P2Y2 receptors induced cell surface redistribution of αv integrin is required for activation of ERK 1/2 in U937 cells NE Chorna, M Chevres, C Santos-Berrios, EA Orellano, L Erb, FA González	Journal of Cellular Physiology	2007
Microenvironmental regulation of biomacromolecular therapies HJ Kong, DJ Mooney	Nature Reviews Drug Discovery	2007
Alpha-v Integrins as Therapeutic Targets in Oncology JA Nemeth, MT Nakada, M Trikha, Z Lang, MS Gordon, GC Jayson, R Corringham, U Prabhakar, HM Davis, RA Beckman	Cancer Investigation	2007
The ITGAV rs3738919-C allele is associated with rheumatoid arthritis in the European Caucasian population: a family-based study. Jacq L, Garnier S, Dieudé P, Michou L, Pierlot C, Migliorini P, Balsa A, Westhovens R, Barrera P, Alves H, Vaz C, Fernandes M, Pascual-Salcedo D, Bombardieri S, Dequeker J, Radstake TR, Van Riel P, van de Putte L, Lopes-Vaz A, Glikmans E, Barbet S, Lasbleiz S, Lemaire I, Quillet P, Hilliquin P, Teixeira VH, Petit-Teixeira E, Mbarek H, Prum B, Bardin T, Cornélis F	Arthritis Research & Therapy	2007
Small molecule drug activity in melanoma models may be dramatically enhanced with an antibody effector M Popkov, C Rader, B Gonzalez, SC Sinha, CF 3rd	International Journal of Cancer	2006
Integrin signaling is critical for pathological angiogenesis GH Mahabeleshwar, W Feng, DR Phillips, TV Byzova	Journal of Experimental Medicine	2006
Angiogenesis blockade as a new therapeutic approach to experimental colitis S Danese, M Sans, DM Spencer, I Beck, F Doñate, ML Plunkett, C la Motte, R Redline, DE Shaw, AD Levine, AP Mazar, C Fiocchi	Gut	2006
Increased expression of the beta4 and alpha5 integrin subunits in cerebral blood vessels of transgenic mice chronically producing the pro-inflammatory cytokines IL-6 or IFN-alpha in the central nervous system R Milner, IL Campbell	Molecular and cellular neurosciences	2006
Clinical implications of angiogenesis in cancers RW Pang, RT Poon	Vascular Health and Risk Management	2006
ADAM15 disintegrin is associated with aggressive prostate and breast cancer disease R Kuefer, KC Day, CG Kleer, MS Sabel, MD Hofer, S Varambally, CS Zorn, AM Chinnaiyan, MA Rubin, ML Day	Neoplasia (New York, N.Y.)	2006
Environmental cues to guide stem cell fate decision for tissue engineering applications E Alsberg, HA von Recum, MJ Mahoney	Expert Opinion on Biological Therapy	2006
Development of microglia in the cerebral white matter of the human fetus and infant SS Billiards, RL Haynes, RD Folkerth, FL Trachtenberg, LG Liu, JJ Volpe, HC Kinney	The Journal of Comparative Neurology	2006
Angiogenesis as a Novel Component of Inflammatory Bowel Disease Pathogenesis S Danese, M Sans, C la Motte, C Graziani, G West, MH Phillips, R Pola, S Rutella, J Willis, A Gasbarrini, C Fiocchi	Gastroenterology	2006
Targeting integrins: Insights into structure and activity of cyclic RGD pentapeptide mimics containing azabicycloalkane amino acids L Belvisi, A Bernardi, M Colombo, L Manzoni, D Potenza, C Scolastico, G Giannini, M Marcellini, T Riccioni, M Castorina, P LoGiudice, C Pisano	Bioorganic & Medicinal Chemistry	2006
Targeting of angiogenic endothelial cells at sites of inflammation by dexamethasone phosphate–containing RGD peptide liposomes inhibits experimental arthritis GA Koning, RM Schiffelers, MH Wauben, RJ Kok, E Mastrobattista, G Molema, TL Hagen, G Storm	Arthritis & Rheumatism	2006
Agrin, a novel basement membrane component in human and rat liver, accumulates in cirrhosis and hepatocellular carcinoma P Tátrai, J Dudás, E Batmunkh, M Máthé, A Zalatnai, Z Schaff, G Ramadori, I Kovalszky	Laboratory Investigation	2006
Discovery of small molecule inhibitors of integrin αvβ3 through structure-based virtual screening Y Zhou, H Peng, Q Ji, J Qi, Z Zhu, C Yang	Bioorganic & Medicinal Chemistry Letters	2006
An improved method of 18F peptide labeling: hydrazone formation with HYNIC-conjugated c(RGDyK) YS Lee, JM Jeong, HW Kim, YS Chang, YJ Kim, MK Hong, GB Rai, DY Chi, WJ Kang, JH Kang, DS Lee, JK Chung, MC Lee, YG Suh	Nuclear Medicine and Biology	2006
Synthesis and biological evaluation of potent αvβ3-integrin receptor antagonists I Dijkgraaf, JA Kruijtzer, C Frielink, AC Soede, HW Hilbers, WJ Oyen, FH Corstens, RM Liskamp, OC Boerman	Nuclear Medicine and Biology	2006
Antibodies and antibody-fusion proteins as anti-angiogenic, anti-tumor agents CI Calfa, JD Rosenblatt, HM Cho, K Webster, SU Shin	Update on cancer therapeutics	2006
The pinpoint promise of nanoparticle-based drug delivery and molecular diagnosis DF Emerich, CG Thanos	Biomolecular Engineering	2006
Integrin alpha v beta 3 antagonist Cilengitide enhances efficacy of radiotherapy in endothelial cell and non-small-cell lung cancer models JM Albert, C Cao, L Geng, L Leavitt, DE Hallahan, B Lu	International journal of radiation oncology, biology, physics	2006
Phase II Evaluations of Cilengitide in Asymptomatic Patients with Androgen-Independent Prostate Cancer: Scientific Rationale and Study Design KW Beekman, AD Colevas, K Cooney, R DiPaola, RL Dunn, M Gross, ET Keller, KJ Pienta, CJ Ryan, D Smith, M Hussain	Clinical Genitourinary Cancer	2006
Study of the labeling of two novel RGD-peptidic derivatives with the precursor [99mTc(H2O)3(CO)3]+ and evaluation for early angiogenesis detection in cancer D Psimadas, M Fani, C Zikos, S Xanthopoulos, SC Archimandritis, AD Varvarigou	Applied Radiation and Isotopes	2006
Stimulation of tPA-dependent provisional extracellular fibrin matrix degradation by human recombinant soluble melanotransferrin Y Bertrand, M Demeule, GE Rivard, R Béliveau	Biochimica et Biophysica Acta (BBA) - Molecular Cell Research	2006
Targeted Therapy for Renal Cell Carcinoma: A New Therapeutic Paradigm PE Shaheen, RM Bukowski	Cancer Investigation	2006
Positron Emission Tomography As an Imaging Biomarker WA Weber	Journal of Clinical Oncology	2006
Construction, expression, and characterization of a new targeted bifunctional fusion protein: Tumstatin45-132-TNF YQ Luo, LH Wang, XL Ma, JX Kong, BH Jiao	IUBMB Life	2006
Ocular Angiogenesis J Tombrain-Tink, CJ Barnstable		2006
The Vascular Endothelium II S Moncada, A Higgs		2006
BioMEMS and Biomedical Nanotechnology M Ferrari, T Desai, S Bhatia		2006
Cell-surface association between matrix metalloproteinases and integrins: role of the complexes in leukocyte migration and cancer progression M Stefanidakis, E Koivunen	Blood	2006
Syndecan-1 regulates αvβ5 integrin activity in B82L fibroblasts KJ McQuade, DM Beauvais, BJ Burbach, AC Rapraeger	Journal of cell science	2006
Delivery of the p38 MAPkinase Inhibitor SB202190 to Angiogenic Endothelial Cells: Development of Novel RGD-Equipped and PEGylated Drug−Albumin Conjugates Using Platinum(II)-Based Drug Linker Technology K Temming, M Lacombe, P van der Hoeven, J Prakash, T Gonzalo, EC Dijkers, L Orfi, G Kéri, K Poelstra, G Molema, RJ Kok	Bioconjugate Chemistry	2006
Novel and Selective α v β 3 Receptor Peptide Antagonist: Design, Synthesis, and Biological Behavior AD Gatto, L Zaccaro, P Grieco, E Novellino, A Zannetti, SD Vecchio, F Iommelli, M Salvatore, C Pedone, M Saviano	Journal of Medicinal Chemistry	2006
Matrix metalloproteinase-9 gene deletion facilitates angiogenesis after myocardial infarction ML Lindsey, GP Escobar, LW Dobrucki, DK Goshorn, S Bouges, JT Mingoia, DM McClister, H Su, J Gannon, C MacGillivray, RT Lee, AJ Sinusas, FG Spinale	American journal of physiology. Heart and circulatory physiology	2005
Up-regulation and profibrotic role of osteopontin in human idiopathic pulmonary fibrosis A Pardo, K Gibson, J Cisneros, TJ Richards, Y Yang, C Becerril, S Yousem, I Herrera, V Ruiz, M Selman, N Kaminski	PLoS Medicine	2005
EXPRESSION OF ANGIOSTATIN, INTEGRIN α v β 3, AND VITRONECTIN IN HUMAN LUNGS IN SEPSIS B Singh, KS Janardhan, R Kanthan	Experimental Lung Research	2005
Nanomedicine: current status and future prospects SM Moghimi, AC Hunter, JC Murray	The FASEB Journal	2005
Angiostatin is a novel anti-inflammatory factor by inhibiting leukocyte recruitment T Chavakis, A Athanasopoulos, JS Rhee, V Orlova, T Schmidt-Wöll, A Bierhaus, AE May, I Celik, PP Nawroth, KT Preissner	Blood	2005
New antiangiogenic strategies for the treatment of proliferative synovitis DT Lainer, E Brahn	Expert Opinion on Investigational Drugs	2005
Angiogenesis and apoptosis in glioma: Two arenas for promising new therapies O Bögler, T Mikkelsen	Journal of Cellular Biochemistry	2005
Drugs to suppress cough KF Chung	Expert Opinion on Investigational Drugs	2005
Efficient targeting of adenoviral vectors to integrin positive vascular cells utilizing a CAR-cyclic RGD linker protein YD Krom, JC Gras, RR Frants, LM Havekes, TJ Berkel, EA Biessen, KW van Dijk	Biochemical and Biophysical Research Communications	2005
Emerging drugs for renal cell carcinoma PE Shaheen, RM Bukowski	Expert Opinion on Emerging Drugs	2005
Phase I investigation of recombinant anti-human vascular endothelial growth factor antibody in patients with advanced cancer GC Jayson, C Mulatero, M Ranson, J Zweit, A Jackson, L Broughton, J Wagstaff, L Hakansson, G Groenewegen, J Lawrance, M Tang, L Wauk, D Levitt, S Marreaud, FF Lehmann, M Herold, H Zwierzina	European Journal of Cancer	2005
Expression, purification, and characterization of a neovasculature targeted rmhTNF-alpha in Escherichia coli H Wang, Z Yan, J Shi, W Han, Y Zhang	Protein Expression and Purification	2005
Synthesis, in vitro, and in vivo characterization of an integrin αvβ3-targeted molecular probe for optical imaging of tumor CA Burnett, J Xie, J Quijano, Z Shen, F Hunter, M Bur, KC Li, SN Danthi	Bioorganic & Medicinal Chemistry	2005
Self-assembled nanoparticles of bile acid-modified glycol chitosans and their applications for cancer therapy K Kim, JH Kim, S Kim, H Chung, K Choi, IC Kwon, JH Park, YS Kim, RW Park, IS Kim, SY Jeong	Macromolecular Research	2005
Angiogenesis and hematological malignancies ST Lim, AM Levine	Hematology	2005
Role of the Vascular Endothelial Growth Factor Pathway in Tumor Growth and Angiogenesis DJ Hicklin, LM Ellis	Journal of Clinical Oncology	2005
Imaging Dose-dependent Pharmacokinetics of an RGD-Fluorescent Dye Conjugate Targeted to α v β 3 Receptor Expressed in Kaposi's Sarcoma S Kwon, S Ke, JP Houston, W Wang, Q Wu, C Li, EM Sevick-Muraca	Molecular imaging	2005
Advances in Radiation Oncology in Lung Cancer B Jeremić		2005
Advanced Concepts in Fluorescence Sensing CD Geddes, JR Lakowicz		2005
Probing for Integrin α v β 3 Binding of RGD Peptides Using Fluorescence Polarization W Wang, Q Wu, M Pasuelo, JS McMurray, C Li	Bioconjugate Chemistry	2005
Antiangiogenic property of pigment epithelium-derived factor in hepatocellular carcinoma K Matsumoto, H Ishikawa, D Nishimura, K Hamasaki, K Nakao, K Eguchi	Hepatology	2004
Regulation of macrophage foam cell formation by alphaVbeta3 integrin: potential role in human atherosclerosis AS Antonov, FD Kolodgie, DH Munn, RG Gerrity	The American Journal of Pathology	2004
Integrative signaling in angiogenesis M Simons	Molecular and Cellular Biochemistry	2004
Mouse Models of Human Cancer R Benezra, S Rafii, D Lyden	Mouse Models of Human Cancer	2004
What the structure of angiostatin may tell us about its mechanism of action JH Geiger, SE Cnudde	Journal of Thrombosis and Haemostasis	2004
Effects of statins on endothelium and their contribution to neovascularization by mobilization of endothelial progenitor cells DH Walter, AM Zeiher, S Dimmeler	Coronary Artery Disease	2004
Ultrasonic analysis of peptide- and antibody-targeted microbubble contrast agents for molecular imaging of alphavbeta3-expressing cells PA Dayton, D Pearson, J Clark, S Simon, PA Schumann, R Zutshi, TO Matsunaga, KW Ferrara	Molecular imaging	2004
Antiangiogenic strategies, compounds, and early clinical results in breast cancer A Morabito, R Sarmiento, P Bonginelli, G Gasparini	Critical Reviews in Oncology/Hematology	2004
Angiogenesis and its role in colorectal tumor and metastasis formation LM Ellis	Seminars in Oncology	2004
CNTO 95, a fully human monoclonal antibody that inhibits ?v integrins, has antitumor and antiangiogenic activityin vivo M Trikha, Z Zhou, JA Nemeth, Q Chen, C Sharp, E Emmell, J Giles-Komar, MT Nakada	International Journal of Cancer	2004
Multiple roles of COX-2 in tumor angiogenesis: a target for antiangiogenic therapy S Gately, WW Li	Seminars in Oncology	2004
Integrin β4 signaling promotes tumor angiogenesis SN Nikolopoulos, P Blaikie, T Yoshioka, W Guo, FG Giancotti	Cancer Cell	2004
Molecular imaging with single photon emission computed tomography FG Blankenberg	IEEE Engineering in Medicine and Biology Magazine	2004
Molecular imaging and therapy directed at the neovasculature in pathologies S Guccione, KC Li, MD Bednarski	IEEE Engineering in Medicine and Biology Magazine	2004
Extracellular fragment of brain-specific angiogenesis inhibitor 1 suppresses endothelial cell proliferation by blocking αvβ5 integrin JT Koh, H Kook, HJ Kee, YW Seo, BC Jeong, JH Lee, MY Kim, KC Yoon, S Jung, KK Kim	Experimental Cell Research	2004
Increased adenoviral transduction efficacy in human laryngeal carcinoma cells resistant to cisplatin is associated with increased expression of integrin ?v?3 and coxsackie adenovirus receptor A Ambriovi?-Ristov, J Gabrilovac, T ?imbora-Zovko, M Osmak	International Journal of Cancer	2004
Photoexcitation-Based Nano-Explorers: Chemical Analysis inside Live Cells and Photodynamic Therapy H Xu, SM Buck, R Kopelman, MA Philbert, M Brasuel, BD Ross, A Rehemtulla	Israel Journal of Chemistry	2004
Piperidine-containing β-arylpropionic acids as potent antagonists of αvβ3/αvβ5 integrins BL de Corte, WA Kinney, L Liu, S Ghosh, L Brunner, WJ Hoekstra, RJ Santulli, RW Tuman, J Baker, C Burns, JC Proost, BA Tounge, BP Damiano, BE Maryanoff, DL Johnson, RA Galemmo	Bioorganic & Medicinal Chemistry Letters	2004
Self-assembled nanoparticles based on glycol chitosan bearing 5β-cholanic acid for RGD peptide delivery JH Park, S Kwon, JO Nam, RW Park, H Chung, SB Seo, IS Kim, IC Kwon, SY Jeong	Journal of Controlled Release	2004
PEGylation enhances tumor targeting of plasmid DNA by an artificial cationized protein with repeated RGD sequences, Pronectin® H Hosseinkhani, Y Tabata	Journal of Controlled Release	2004
The possible role of matrix metalloproteinase (MMP)-2 and MMP-9 in cancer, e.g. acute leukemia G Klein, E Vellenga, MW Fraaije, WA Kamps, ES Bont	Critical Reviews in Oncology/Hematology	2004
NK95806, a newly synthesized microtubule-disrupting agent that suppresses collagen-induced arthritis in mice H Morohashi, F Abe, K Saiga, E Toyoda, E Ichimura, K Nishikawa	International Immunopharmacology	2004
PET: a revolution in medical imaging A Alavi, P Lakhani, A Mavi, JW Kung, H Zhuang	Radiologic Clinics of North America	2004
The vascular endothelial growth factor family and its receptors AA Parikh, LM Ellis	Hematology/Oncology Clinics of North America	2004
The role of integrins in tumor angiogenesis R Hwang, J Varner	Hematology/Oncology Clinics of North America	2004
Implications of proprotein Convertase 5 (PC5) in the arterial restenotic process in a porcine model JP Veinot, W Prichett-Pejic, P Picard, W Parks, R Schwartz, NG Seidah, M Chretien	Cardiovascular Pathology	2004
Vasculogenesis and Angiogenesis: Molecular and Cellular Controls. Part 2: Interactions between Cell and Extracellular Environment N Kubis, BI Levy	Interventional Neuroradiology	2004
Vasculogenesis and Angiogenesis: Molecular and Cellular Controls N Kubis, BI Levy	Interventional Neuroradiology	2004
Gene microarray analysis of human brain arteriovenous malformations Tomoki Hashimoto, Michael T Lawton, Gen Wen, Guo-Yuan Yang, Thomas Chaly Jr, Campbell L Stewart, Holly K Dressman, Nicholas M Barbaro, Douglas A Marchuk, William L Young	Neurosurgery	2004
Implications of PET based molecular imaging on the current and future practice of medicine A Alavi, JW Kung, H Zhuang	Seminars in Nuclear Medicine	2004
Ultrasonic Analysis of Peptide- and Antibody-Targeted Microbubble Contrast Agents for Molecular Imaging of α v β 3 -Expressing Cells PA Dayton, D Pearson, J Clark, S Simon, PA Schumann, R Zutshi, TO Matsunaga, KW Ferrara	Molecular imaging	2004
Near-Infrared Optical Imaging of Integrin α v β 3 in Human Tumor Xenografts W Wang, S Ke, Q Wu, C Charnsangavej, M Gurfinkel, JG Gelovani, JL Abbruzzese, EM Sevick-Muraca, C Li	Molecular imaging	2004
Cancer and Inflammation DW Morgan, UJ Forssmann, MT Nakada		2004
Cancer Metastasis, Molecular and Cellular Mechanisms and Clinical Intervention WG Jiang, RE Mansel		2004
Antiangiogenic gene therapy of cancer: recent developments A Tandle, DG Blazer, SK Libutti	Journal of Translational Medicine	2004
Anti-angiogenic action of the C-terminal domain of tenomodulin that shares homology with chondromodulin-I Y Oshima, K Sato, F Tashiro, J Miyazaki, K Nishida, Y Hiraki, Y Tano, C Shukunami	Journal of cell science	2004
Neovascularization of ischemic tissues by gene delivery of the extracellular matrix protein Del1 Jingping Zhong, Brian Eliceiri, Dwayne Stupack, Kaliani Penta, Gordon Sakamoto, Richard O. Hynes, Thomas Quertermous, Mike Coleman, Nancy Boudreau and Judith A. Varner	Journal of Clinical Investigation	2003
Matrix-fibrinogen enhances wound closure by increasing both cell proliferation and migration BJ Rybarczyk, SO Lawrence, PJ Simpson-Haidaris	Blood	2003
Collagenase cleavage of type I collagen is essential for both basal and parathyroid hormone (PTH)/PTH-related peptide receptor-induced osteoclast activation and has differential effects on discrete bone compartments R Chiusaroli, A Maier, MC Knight, M Byrne, LM Calvi, R Baron, SM Krane, E Schipani	Endocrinology	2003
Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration S Rafii, D Lyden	Nature Medicine	2003
Angiogenesis of the heart MJ Kutryk, DJ Stewart	Microscopy Research and Technique	2003
Comparison of developmental endothelial locus-1 angiogenic factor with vascular endothelial growth factor in a porcine model of cardiac ischemia MH Kown, T Suzuki, ML Koransky, K Penta, G Sakamoto, CL Jahncke, AJ Carter, T Quertermous, RC Robbins	The Annals of Thoracic Surgery	2003
Modulation of Rho GTPase activity in endothelial cells by selective proteinase-activated receptor (PAR) agonists V Vouret-Craviari, D Grall, EV Obberghen-Schilling	Journal of Thrombosis and Haemostasis	2003
Nucleolin expressed at the cell surface is a marker of endothelial cells in angiogenic blood vessels S Christian, J Pilch, ME Akerman, K Porkka, P Laakkonen, E Ruoslahti	The Journal of Cell Biology	2003
Clinical significance of angiogenesis in gastrointestinal cancers: a target for novel prognostic and therapeutic approaches RT Poon, ST Fan, J Wong	Annals of Surgery	2003
New Approaches to the Treatment of Hepatic Malignancies Angiogenesis and Antiangiogenic Therapy of Colon Cancer Liver Metastasis O Stoeltzing, W Liu, N Reinmuth, A Parikh, SA Ahmad, YD Jung, F Fan, LM Ellis	Annals of Surgical Oncology	2003
Design and synthesis of 1,5- and 2,5-substituted tetrahydrobenzazepinones as novel potent and selective integrin αVβ3 antagonists A Kling, G Backfisch, J Delzer, H Geneste, C Graef, W Hornberger, UE Lange, A Lauterbach, W Seitz, T Subkowski	Bioorganic & Medicinal Chemistry	2003
Integrin 3 Leu33Pro Homozygosity and Risk of Cancer SE Bojesen, A Tybjaerg-Hansen, BG Nordestgaard	JNCI Journal of the National Cancer Institute	2003
Novel chemotherapeutic agents for the treatment of glioblastoma multiforme V Jendrossek, C Belka, M Bamberg	Expert Opinion on Investigational Drugs	2003
Significance of endothelial cell survival programs for renal transplantation AV Hall, AM Jevnikar	American Journal of Kidney Diseases	2003
Promises and pitfalls of anti-angiogenic therapy in clinical trials MF McCarty, W Liu, F Fan, A Parikh, N Reimuth, O Stoeltzing, LM Ellis	Trends in Molecular Medicine	2003
Ovarian Cancer Cell Proliferation and Motility Is Induced by Engagement of Integrin αvβ3/Vitronectin Interaction S Hapke, H Kessler, B Luber, A Benge, P Hutzler, H Höfler, M Schmitt, U Reuning	Biological Chemistry	2003
Functional Overlap and Cooperativity Among αv and β1 Integrin Subfamilies During Skin Angiogenesis CA Perruzzi, AR de Fougerolles, VE Koteliansky, MC Whelan, WF Westlin, DR Senger	Journal of Investigative Dermatology	2003
Lung Biology in Health and Disease N Zamel	Lung Biology in Health and Disease: Experimental Models and Therapeutic Potential	2003
Modulation of cell death in the tumor microenvironment BG Wouters, M Koritzinsky, RK Chiu, J Theys, J Buijsen, P Lambin	Seminars in radiation oncology	2003
Inhibition of angiogenesis by non-toxic doses of temozolomide: H Kurzen, S Schmitt, H N??her, T M??hler	Anti-Cancer Drugs	2003
Vasculogenesis and Angiogenesis: Molecular and Cellular Controls: Part 2: Interactions between Cell and Extracellular Environment N Kubis, BI Levy	Interventional Neuroradiology	2003
The Homeobox Transcription Factor Hox D3 Promotes Integrin α 5 β 1 Expression and Function during Angiogenesis NJ Boudreau, JA Varner	The Journal of biological chemistry	2003
A Recombinant Chimeric Epidermal Growth Factor-like Module with High Binding Affinity for Integrins F Vella, NM Thielens, B Bersch, GJ Arlaud, P Frachet	The Journal of biological chemistry	2003
Angiogenesis: Basic Mechanisms and Clinical Applications V Chhokar, AL Tucker	Seminars in cardiothoracic and vascular anesthesia	2003
RAF antisense oligonucleotide as a tumor radiosensitizer U Kasid, A Dritschilo	Oncogene	2003
Molecular imaging: The latest generation of contrast agents and tissue characterization techniques FG Blankenberg	Journal of Cellular Biochemistry	2003
The Macrophage as Therapeutic Target S Gordon		2003
[ 18 F]Galacto-RGD: Synthesis, Radiolabeling, Metabolic Stability, and Radiation Dose Estimates R Haubner, B Kuhnast, C Mang, WA Weber, H Kessler, HJ Wester, M Schwaiger	Bioconjugate Chemistry	2003
Coordinated regulation and colocalization of αv integrin and its activating enzyme proprotein convertase PC5 in vivo P Stawowy, K Graf, S Goetze, M Roser, M Chrétien, NG Seidah, E Fleck, M Marcinkiewicz	Histochemistry and Cell Biology	2003
Potential Role for ADAM15 in Pathological Neovascularization in Mice K Horiuchi, G Weskamp, L Lum, HP Hammes, H Cai, TA Brodie, T Ludwig, R Chiusaroli, R Baron, KT Preissner, K Manova, CP Blobel	Molecular and cellular biology	2003
Endothelial expression of the α6β4 integrin is negatively regulated during angiogenesis TS Hiran, JE Mazurkiewicz, P Kreienberg, FL Rice, SE LaFlamme	Journal of cell science	2003
Positron emission tomography (PET): expanding the horizons of oncology drug development Lisa A Hammond, Louis Denis, Umber Salman, Paul Jerabek, Charles R Thomas Jr, John G Kuhn	Investigational New Drugs	2003
Inhibition of alpha(v)beta3 integrin reduces angiogenesis, bone turnover, and tumor cell proliferation in experimental prostate cancer bone metastases Jeffrey A Nemeth, Michael L Cher, Zhao Zhou, Chadwick Mullins, Sunita Bhagat, Mohit Trikha	Clinical & Experimental Metastasis	2003
Statin therapy accelerates reendothelialization: a novel effect involving mobilization and incorporation of bone marrow-derived endothelial progenitor cells DH Walter, K Rittig, FH Bahlmann, R Kirchmair, M Silver, T Murayama, H Nishimura, DW Losordo, T Asahara, JM Isner	Circulation	2002
Sustained expression of homeobox D10 inhibits angiogenesis C Myers, A Charboneau, I Cheung, D Hanks, N Boudreau	The American Journal of Pathology	2002
Mutation in collagen-1 that confers resistance to the action of collagenase results in failure of recovery from CCl4-induced liver fibrosis, persistence of activated hepatic stellate cells, and diminished hepatocyte regeneration R Issa, X Zhou, N Trim, H Millward-Sadler, S Krane, C Benyon, J Iredale	The FASEB Journal	2002
Novel lipid mediator regulators of endothelial cell proliferation and migration: aspirin-triggered-15R-lipoxin A(4) and lipoxin A(4) IM Fierro, JL Kutok, CN Serhan	The Journal of pharmacology and experimental therapeutics	2002
The αvintegrin antagonists as novel anticancer agents: an update JS Kerr, AM Slee, SA Mousa	Expert Opinion on Investigational Drugs	2002
Inhibition of the alpha-ν integrins with a cyclic RGD peptide impairs angiogenesis, growth and metastasis of solid tumours in vivo MA Buerkle, SA Pahernik, A Sutter, A Jonczyk, K Messmer, M Dellian	British Journal of Cancer	2002
The Diverse Roles of Integrins and Their Ligands in Angiogenesis R Hynes, J Lively, J Mccarty, D Taverna, S Francis, K Hodivala-Dilke, Q Xiao	Cold Spring Harbor Symposia on Quantitative Biology	2002
Complex interactions between the laminin alpha 4 subunit and integrins regulate endothelial cell behavior in vitro and angiogenesis in vivo AM Gonzalez, M Gonzales, GS Herron, U Nagavarapu, SB Hopkinson, D Tsuruta, JC Jones	Proceedings of the National Academy of Sciences	2002
Integrin alpha V beta 3 as a target for treatment of rheumatoid arthritis and related rheumatic diseases RL Wilder	Annals of the rheumatic diseases	2002
A p130Cas tyrosine phosphorylated substrate domain decoy disrupts v-crk signaling K Kirsch, M Kensinger, H Hanafusa, A August	BMC cell biology	2002
beta8 integrins are required for vascular morphogenesis in mouse embryos J Zhu, K Motejlek, D Wang, K Zang, A Schmidt, LF Reichardt	Development (Cambridge, England)	2002
Encyclopedia of Cancer G Sgouros	Encyclopedia of Cancer	2002
Recent advances in cutaneous angiogenesis M Bhushan, HS Young, PE Brenchley, CE Griffiths	British Journal of Dermatology	2002
Immunotherapy of tumors with vaccines based on xenogeneic homologous molecules Y Wei	Anti-Cancer Drugs	2002
The integrin family of cell adhesion molecules has multiple functions within the CNS R Milner, IL Campbell	Journal of Neuroscience Research	2002
SPECIALIZATION OF TUMOUR VASCULATURE E Ruoslahti	Nature Reviews Cancer	2002
Mit Integrinen zu neuen Therapien N Sewald	Nachrichten aus der Chemie	2002
Anti-integrin as novel drug-discovery targets: potential therapeutic and diagnostic implications SA Mousa	Current Opinion in Chemical Biology	2002
Drug targeting to specific vascular sites E Ruoslahti	Drug Discovery Today	2002
Endothelial cells internalize and degrade RGD-modified proteins developed for tumor vasculature targeting AJ Schraa, RJ Kok, AD Berendsen, HE Moorlag, EJ Bos, DK Meijer, LF de Leij, G Molema	Journal of Controlled Release	2002
Identification of Endothelial Cell Genes Expressed in an in Vitro Model of Angiogenesis: Induction of ESM-1, βig-h3, and NrCAM M Aitkenhead, SJ Wang, MN Nakatsu, J Mestas, C Heard, CC Hughes	Microvascular Research	2002
Methods in Cell Biology JW Smith	Methods in cell biology	2002
Relationship between vascular development and vascular differentiation during liver organogenesis in humans G Gouysse, A Couvelard, S Frachon, R Bouvier, M Nejjari, MC Dauge, G Feldmann, D Hénin, JY Scoazec	Journal of Hepatology	2002
Characterization of a monomeric disintegrin, ocellatusin, present in the venom of the Nigerian carpet viper, Echis ocellatus JB Smith, RD Theakston, AL Coelho, C Barja-Fidalgo, JJ Calvete, C Marcinkiewicz	FEBS Letters	2002
A reevaluation of integrins as regulators of angiogenesis RO Hynes	Nature Medicine	2002
Advances in the treatment of liver tumors SA Curley, JC Cusack, KK Tanabe, LM Ellis	Current Problems in Surgery	2002
IMMUNOGENE THERAPY OF TUMORS WITH A VACCINE BASED ON THE LIGAND-BINDING DOMAIN OF CHICKEN HOMOLOGOUS INTEGRIN β 3 Y Lou, Y Wei, L Yang, X Zhao, L Tian, Y Lu, Y Wen, F Liu, M Huang, B Kang, F Xiao, J Su, Q He, X Xie, Y Mao, S Lei, J Liu, F Lou, L Zhou, F Peng, Y Jiang, B Hu	Immunological Investigations	2002
Novel Targets for Lung Cancer Therapy: Part II GK Dy, AA Adjei	Journal of Clinical Oncology	2002
Plasmin-induced Migration of Endothelial Cells: A POTENTIAL TARGET FOR THE ANTI-ANGIOGENIC ACTION OF ANGIOSTATIN T Tarui, M Majumdar, LA Miles, W Ruf, Y Takada	The Journal of biological chemistry	2002
?v-Integrin antagonist EMD 121974 induces apoptosis in brain tumor cells growing on vitronectin and tenascin T Taga, A Suzuki, I Gonzalez-Gomez, FH Gilles, M Stins, H Shimada, L Barsky, KI Weinberg, WE Laug	International Journal of Cancer	2002
Osteopontin induces angiogenesis of murine neuroblastoma cells in mice F Takahashi, S Akutagawa, H Fukumoto, S Tsukiyama, Y Ohe, K Takahashi, Y Fukuchi, N Saijo, K Nishio	International Journal of Cancer	2002
Anti-neovascular therapy using novel peptides homing to angiogenic vessels N Oku, T Asai, K Watanabe, K Kuromi, M Nagatsuka, K Kurohane, H Kikkawa, K Ogino, M Tanaka, D Ishikawa, H Tsukada, M Momose, J Nakayama, T Taki	Oncogene	2002
Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium–derived factor OV Volpert, T Zaichuk, W Zhou, F Reiher, TA Ferguson, PM Stuart, M Amin, NP Bouck	Nature Medicine	2002
On the mechanism of thrombin-induced angiogenesis: involvement of α v β 3 -integrin NE Tsopanoglou, P Andriopoulou, ME Maragoudakis	American journal of physiology. Cell physiology	2002
Mechanisms of normal and tumor-derived angiogenesis M Papetti, IM Herman	American journal of physiology. Cell physiology	2002
Nuclear medicine applications in molecular imaging FG Blankenberg, HW Strauss	Journal of magnetic resonance imaging : JMRI	2002
Enhanced pathological angiogenesis in mice lacking β3 integrin or β3 and β5 integrins LE Reynolds, L Wyder, JC Lively, D Taverna, SD Robinson, X Huang, D Sheppard, RO Hynes, KM Hodivala-Dilke	Nature Medicine	2002
Central Roles of α 5 β 1 Integrin and Fibronectin in Vascular Development in Mouse Embryos and Embryoid Bodies SE Francis, KL Goh, K Hodivala-Dilke, BL Bader, M Stark, D Davidson, RO Hynes	Arteriosclerosis, thrombosis, and vascular biology	2002
Thalidomide in Cancer Treatment: A Potential Role in the Elderly? S Zhou, P Kestell, MD Tingle, JW Paxton	Drugs & Aging	2002
Pan Vascular Medicine P Lanzer, EJ Topol		2002
What's going on? K Novak	Nature Reviews Cancer	2002
Assembly of the Vasculature and Its Regulation RJ Tomanek		2002
Activated Notch4 Inhibits Angiogenesis: Role of β1-Integrin Activation KG Leong, X Hu, L Li, M Noseda, B Larrivée, C Hull, L Hood, F Wong, A Karsan	Molecular and cellular biology	2002
β8 integrins are required for vascular morphogenesis in mouse embryos J Zhu, K Motejlek, D Wang, K Zang, A Schmidt, LF Reichardt	Development (Cambridge, England)	2002
Identification of the Principal Binding Site for RGD-Containing Ligands in the α V β 3 Integrin: A Photoaffinity Cross-Linking Study D Yahalom, A Wittelsberger, DF Mierke, M Rosenblatt, JM Alexander, M Chorev	Biochemistry	2002
Dual role for TWEAK in angiogenic regulation A Jakubowski, B Browning, M Lukashev, I Sizing, JS Thompson, CD Benjamin, YM Hsu, C Ambrose, TS Zheng, LC Burkly	Journal of cell science	2002
How matrix metalloproteinases regulate cell behavior MD Sternlicht, Z Werb	Annual Review of Cell and Developmental Biology	2001
ROLE OFOSTEOPONTIN INCELLULARSIGNALING ANDTOXICANTINJURY1 DT Denhardt, CM Giachelli, SR Rittling	Annual Review of Pharmacology and Toxicology	2001
POTENTIAL BIOLOGIC AGENTS FOR TREATING RHEUMATOID ARTHRITIS LW Moreland	Rheumatic Disease Clinics of North America	2001
Antiangiogenic agents and their promising potential in combined therapy PA Burke, SJ DeNardo	Critical Reviews in Oncology/Hematology	2001
Angiogenesis-dependent diseases and angiogenesis therapy J Tímár, B Döme, K Fazekas, Á Janovics, S Paku	Pathology & Oncology Research	2001
A Pilot Trial of Vitaxin, A Humanized Anti-Vitronectin Receptor (antiαvβ3) Antibody in Patients with Metastatic Cancer JA Posey, MB Khazaeli, A DelGrosso, MN Saleh, CY Lin, W Huse, AF LoBuglio	Cancer Biotherapy & Radiopharmaceuticals	2001
Novel pharmacological agents in clinical development for solid tumours GK Dy, P Haluska, AA Adjei	Expert Opinion on Investigational Drugs	2001
Immunothérapie de la polyarthrite rhumatoïde par transfert de gène : perspectives C Jorgensen	La Revue de Médecine Interne	2001
Tumor angiogenesis as a therapeutic target A Matter	Drug Discovery Today	2001
Emerging therapies in osteoporosis BR MacDonald, M Gowen	Best Practice & Research Clinical Rheumatology	2001
Angiogenesis: pathological, prognostic, and growth-factor pathways and their link to trial design and anticancer drugs SB Fox, G Gasparini, AL Harris	The Lancet Oncology	2001
Prominent Beta-5 Gene Expression in the Cardiovascular System and in the Cartilaginous Primordiae of the Skeleton During Mouse Development LL Gat, S Bonnel, K Gogat, M Brizard, LV Berghe, A Kobetz, S Gadin, P Dureau, JL Dufier, M Abitbol, M Menasche	Cell Communication and Adhesion	2001
Integrin-Specific Activation of Rac Controls Progression through the G1 Phase of the Cell Cycle A Mettouchi, S Klein, W Guo, M Lopez-Lago, E Lemichez, JK Westwick, FG Giancotti	Molecular Cell	2001
Tumors and Fibrinogen P Simpson-Haidaris, B Rybarczyk	Annals of the New York Academy of Sciences	2001
Low-power helium: Neon laser irradiation enhances production of vascular endothelial growth factor and promotes growth of endothelial cells in vitro N Kipshidze, V Nikolaychik, MH Keelan, LR Shankar, A Khanna, R Kornowski, M Leon, J Moses	Lasers in Surgery and Medicine	2001
Surgical Research J Rozga, AA Demetriou	Surgical Research	2001
Angiogenesis: regulators and clinical applications S Liekens, ED Clercq, J Neyts	Biochemical Pharmacology	2001
Membrane Type 1-Matrix Metalloproteinase Is Activated during Migration of Human Endothelial Cells and Modulates Endothelial Motility and Matrix Remodeling BG Gálvez, S Matı́as-Román, JP Albar, F Sánchez-Madrid, AG Arroyo	The Journal of biological chemistry	2001
Specific Interaction of Angiostatin with Integrin α v β 3 in Endothelial Cells T Tarui, LA Miles, Y Takada	The Journal of biological chemistry	2001
Sphingosine 1-Phosphate-induced Endothelial Cell Migration Requires the Expression of EDG-1 and EDG-3 Receptors and Rho-dependent Activation of α v β 3 - and β 1 -containing Integrins JH Paik, S Chae, MJ Lee, S Thangada, T Hla	The Journal of biological chemistry	2001
DNAzymes to β 1 and β 3 mRNA Down-regulate Expression of the Targeted Integrins and Inhibit Endothelial Cell Capillary Tube Formation in Fibrin and Matrigel M Cieslak, J Niewiarowska, M Nawrot, M Koziolkiewicz, WJ Stec, CS Cierniewski	The Journal of biological chemistry	2001
Tumor-derived Osteopontin Is Soluble, Not Matrix Associated SR Rittling, Y Chen, F Feng, Y Wu	The Journal of biological chemistry	2001
Integrin αvβ3 Expression in Colon Carcinoma Correlates with Survival A Vonlaufen, G Wiedle, B Borisch, S Birrer, P Luder, BA Imhof	Modern Pathology	2001
Integrin αvβ3 promotes anchorage-dependent apoptosis in human intestinal carcinoma cells NI Kozlova, GE Morozevich, AN Chubukina, AE Berman	Oncogene	2001
Anticancer Therapy with Angiogenesis Inhibitors C Ghilardi, MR Bani, R Giavazzi	TUMORI	2001
Integrin and Growth Factor Receptor Crosstalk BP Eliceiri	Circulation research	2001
Crystal Structure of the Extracellular Segment of Integrin αVβ3 JP Xiong, T Stehle, B Diefenbach, R Zhang, R Dunker, DL Scott, A Joachimiak, SL Goodman, MA Arnaout	Science	2001
The Vascular Endothelial Growth Factor (VEGF) Signaling Pathway: A Therapeutic Target in Patients with Hematologic Malignancies FJ Giles	The oncologist	2001
Ligand binding to integrin αvβ3requires tyrosine 178 in the αv subunit S Honda, Y Tomiyama, N Pampori, H Kashiwagi, T Kiyoi, S Kosugi, S Tadokoro, Y Kurata, SJ Shattil, Y Matsuzawa	Blood	2001
Rhodostomin, A Snake Venom Disintegrin, Inhibits Angiogenesis Elicited by Basic Fibroblast Growth Factor and Suppresses Tumor Growth by A Selective α v β 3 Blockade of Endothelial Cells CH Yeh, HC Peng, RS Yang, TF Huang	Molecular pharmacology	2001
Interaction of endostatin with integrins implicated in angiogenesis. Rehn M, Veikkola T, Kukk-Valdre E, Nakamura H, Ilmonen M, Lombardo C, Pihlajaniemi T, Alitalo K, Vuori K	Proceedings of the National Academy of Sciences	2001
Inability of collagenase to cleave type I collagen in vivo is associated with osteocyte apoptosis and excessive bone deposition Weiguang Zhao, Michael H. Byrne, Yingmin Wang, Stephen M. Krane	Journal of Clinical Investigation	2000
Tumor Angiogenesis M Detmar	Journal of Investigative Dermatology Symposium Proceedings	2000
No grip, no growth: the conceptual basis of excessive proteolysis in the treatment of cancer A Reijerkerk	European Journal of Cancer	2000
Characterization of Lymphocyte-Dependent Angiogenesis Using a SCID Mouse: Human Skin Model of Psoriasis BJ Nickoloff	Journal of Investigative Dermatology Symposium Proceedings	2000
Ligands to the integrin receptor αvβ3 ME Duggan, JH Hutchinson	Expert Opinion on Therapeutic Patents	2000
Identification and in vivo efficacy of small-molecule antagonists of integrin αvβ3 (the vitronectin receptor) WH Miller, RM Keenan, RN Willette, MW Lark	Drug Discovery Today	2000
Integrin cell adhesion receptors and the concept of agonism MJ Humphries	Trends in Pharmacological Sciences	2000
Molecular mechanisms that control endothelial cell contacts D Vestweber	The Journal of Pathology	2000
A Mechanism for Modulation of Cellular Responses to VEGF TV Byzova, CK Goldman, N Pampori, KA Thomas, A Bett, SJ Shattil, EF Plow	Molecular Cell	2000
Integrins as novel drug discovery targets: potential therapeutic and diagnostic implications SA Mousa	Expert Opinion on Therapeutic Targets	2000
An Address System in the Vasculature of Normal Tissues and Tumors E Ruoslahti, D Rajotte	Annual Review of Immunology	2000
In vivo monitoring of tumor angiogenesis with MR imaging RC Brasch, KC Li, JE Husband, MT Keogan, M Neeman, AR Padhani, D Shames, K Turetschek	Academic Radiology	2000
Role of radionuclide imaging in trials of antiangiogenic therapy FG Blankenberg, WC Eckelman, HW Strauss, MJ Welch, A Alavi, C Anderson, S Bacharach, RG Blasberg, MM Graham, W Weber	Academic Radiology	2000
Tumor angiogenesis: Molecular pathology, therapeutic targeting, and imaging WW Li	Academic Radiology	2000
Endothelial signal integration in vascular assembly TO Daniel, D Abrahamson	Annual Review of Physiology	2000
Endostatin inhibits endothelial and tumor cellular invasion by blocking the activation and catalytic activity of matrix metalloproteinase M Rehn, T Veikkola, E Kukk-Valdre, H Nakamura, M Ilmonen, C Lombardo, T Pihlajaniemi, K Alitalo, K Vuori	Cancer research	2000
Angiogenèse : mécanismes généraux et implications au cours de la polyarthrite rhumatoïde AJ Weber, MD Bandt	Revue du Rhumatisme	2000
Effective targeting of tumor vasculature by the angiogenesis inhibitors vasostatin and interleukin-12 L Yao, SE Pike, J Setsuda, J Parekh, G Gupta, M Raffeld, ES Jaffe, G Tosato	Blood	2000
Les nouvelles cibles pour le traitement de la polyarthrite rhumatoïde C Jorgensen	Revue du Rhumatisme	2000
Activation of Integrin αVβ3 Regulates Cell Adhesion and Migration to Bone Sialoprotein TV Byzova, W Kim, RJ Midura, EF Plow	Experimental Cell Research	2000
Factor VIIa and Thrombin Induce the Expression of Cyr61 and Connective Tissue Growth Factor, Extracellular Matrix Signaling Proteins That Could Act as Possible Downstream Mediators in Factor VIIa·Tissue Factor-induced Signal Transduction UR Pendurthi, KE Allen, M Ezban, LV Rao	The Journal of biological chemistry	2000
Substrate Specificity of α v β 3 Integrin-mediated Cell Migration and Phosphatidylinositol 3-Kinase/AKT Pathway Activation DQ Zheng, AS Woodard, G Tallini, LR Languino	The Journal of biological chemistry	2000
Identification of Amino Acid Sequences in Fibrinogen γ-Chain and Tenascin C C-terminal Domains Critical for Binding to Integrin α v β 3 K Yokoyama, HP Erickson, Y Ikeda, Y Takada	The Journal of biological chemistry	2000
Mechanical stress-initiated signal transductions in vascular smooth muscle cells C Li, Q Xu	Cellular Signalling	2000
Immunotherapy of tumors with xenogeneic endothelial cells as a vaccine Y Wei, Q Wang, X Zhao, L Yang, L Tian, Y Lu, B Kang, C Lu, M Huang, Y Lou, F Xiao, Q He, J Shu, X Xie, Y Mao, S Lei, F Luo, L Zhou, C Liu, H Zhou, Y Jiang, F Peng, L Yuan, Q Li, Y Wu, J Liu	Nature Medicine	2000
α v β 3 Integrin Induces Tyrosine Phosphorylation–Dependent Ca 2+ Influx in Pulmonary Endothelial Cells S Bhattacharya, X Ying, C Fu, R Patel, W Kuebler, S Greenberg, J Bhattacharya	Circulation research	2000
Angiotensin II Enhances Integrin and α-Actinin Expression in Adult Rat Cardiac Fibroblasts H Kawano, RJ Cody, K Graf, S Goetze, Y Kawano, J Schnee, RE Law, WA Hsueh	Hypertension	2000
Estrogen Attenuates Integrin-β 3 –Dependent Adventitial Fibroblast Migration After Inhibition of Osteopontin Production in Vascular Smooth Muscle Cells G Li, YF Chen, SS Kelpke, S Oparil, JA Thompson	Circulation	2000
Progress in Anti-Cancer Chemotherapy D Khayat, GN Hortobagyi		2000
Functional Analyses of Two Cellular Binding Domains of Bovine Lactadherin MH Andersen, H Graversen, SN Fedosov, TE Petersen, JT Rasmussen	Biochemistry	2000
Urokinase receptor expression on human microvascular endothelial cells is increased by hypoxia: implications for capillary-like tube formation in a fibrin matrix ME Kroon, P Koolwijk, B van der Vecht, VW van Hinsbergh	Blood	2000
Introduction: anti-adhesion therapy in sickle cell disease JM Harlan	Blood	2000
Mechanism-Based Target Identification and Drug Discovery in Cancer Research JB Gibbs	Science	2000
Functional Genomic Analysis in Arthritis-Affected Cartilage: Yin-Yang Regulation of Inflammatory Mediators by α 5 β 1 and α V β 3 Integrins MG Attur, MN Dave, RM Clancy, IR Patel, SB Abramson, AR Amin	Journal of immunology (Baltimore, Md. : 1950)	2000
Anticancer drug targets: approaching angiogenesis E Keshet, SA Ben-Sasson	Journal of Clinical Investigation	1999
Anti-integrins as a potential therapeutic target in angiogenesis SA Mousa	Expert Opinion on Therapeutic Patents	1999
Endothelial adhesion molecules in the development of the vascular tree: the garden of forking paths G Bazzoni, E Dejana, MG Lampugnani	Current Opinion in Cell Biology	1999
Antiangiogenic agents WD Klohs, JM Hamby	Current Opinion in Biotechnology	1999
Vascular Endothelial Cell Adherens Junction Assembly and Morphogenesis Induced by Sphingosine-1-Phosphate MJ Lee, S Thangada, KP Claffey, N Ancellin, CH Liu, M Kluk, M Volpi, RI Sha'afi, T Hla	Cell	1999
Discovery of Orally Active Nonpeptide Vitronectin Receptor Antagonists Based on a 2-Benzazepine Gly-Asp Mimetic WH Miller, DP Alberts, PK Bhatnagar, WE Bondinell, JF Callahan, RR Calvo, RD Cousins, KF Erhard, DA Heerding, RM Keenan, C Kwon, PJ Manley, KA Newlander, ST Ross, JM Samanen, IN Uzinskas, JW Venslavsky, CC Yuan, RC Haltiwanger, M Gowen, SM Hwang, IE James, MW Lark, DJ Rieman, GB Stroup, LM Azzarano, KL Salyers, BR Smith, KW Ward, KO Johanson, WF Huffman	Journal of Medicinal Chemistry	1999
Of Man and Mouse: Leukocyte and Endothelial Adhesion Molecule Deficiencies A Etzioni, CM Doerschuk, JM Harlan	Blood	1999
Antiangiogenesis Is Produced by Nontoxic Doses of Vinblastine A Vacca, M Iurlaro, D Ribatti, M Minischetti, B Nico, R Ria, A Pellegrino, F Dammacco	Blood	1999
Angiogenesis as a target for breast cancer therapy D Rayson, S A Vantyghem, A F Chambers	Journal of Mammary Gland Biology and Neoplasia	1999
Development of a method for measuring myocardial contractility with gated myocardial SPECT and arterial tonometry D Lee	Journal of Nuclear Cardiology	1999

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