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Usage Information

Oncometabolites: linking altered metabolism with cancer
Ming Yang, … , Tomoyoshi Soga, Patrick J. Pollard
Ming Yang, … , Tomoyoshi Soga, Patrick J. Pollard
Published September 3, 2013
Citation Information: J Clin Invest. 2013;123(9):3652-3658. https://doi.org/10.1172/JCI67228.
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Review Series Article has an altmetric score of 22

Oncometabolites: linking altered metabolism with cancer

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Abstract

The discovery of cancer-associated mutations in genes encoding key metabolic enzymes has provided a direct link between altered metabolism and cancer. Advances in mass spectrometry and nuclear magnetic resonance technologies have facilitated high-resolution metabolite profiling of cells and tumors and identified the accumulation of metabolites associated with specific gene defects. Here we review the potential roles of such “oncometabolites” in tumor evolution and as clinical biomarkers for the detection of cancers characterized by metabolic dysregulation.

Authors

Ming Yang, Tomoyoshi Soga, Patrick J. Pollard

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Usage data is cumulative from May 2024 through May 2025.

Usage JCI PMC
Text version 2,068 221
PDF 130 52
Figure 156 4
Citation downloads 106 0
Totals 2,460 277
Total Views 2,737
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