In addition to its role in refraction, the cornea forms a barrier between the eye and environmental and infectious insults. Corneal infections are surprisingly rare, suggesting that multiple aspects of the immune system are at play in mediating protection. In this issue of the JCI, Tam et al. describe the unexpected role of a structural protein, cytokeratin 6A, in this process.
Michael Zasloff
Title and authors | Publication | Year |
---|---|---|
Mass Spectrometric Detection of Keratins in Tear Fluid
Ahmed S, Altman J, Jones G, Lee TJ, Robertson DM, Zhi W, Sharma S, Sharma A |
Experimental eye research | 2025 |
Epithelial Intermediate Filaments: Guardians against Microbial Infection?
F Geisler, R Leube |
Cells | 2016 |
Cornea and Ocular Surface Disease: Application of Cutting-Edge Optometric Research
DM Robertson, LJ Alexander, JA Bonanno, SM Fleiszig, N McNamara |
Optometry and Vision Science | 2014 |
Why Does the Healthy Cornea Resist Pseudomonas aeruginosa Infection?
DJ Evans, SM Fleiszig |
American Journal of Ophthalmology | 2013 |