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Citations to this article

Yes, even human brown fat is on fire!
Barbara Cannon, Jan Nedergaard
Barbara Cannon, Jan Nedergaard
Published January 24, 2012
Citation Information: J Clin Invest. 2012;122(2):486-489. https://doi.org/10.1172/JCI60941.
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Commentary Article has an altmetric score of 16

Yes, even human brown fat is on fire!

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Abstract

That adult humans possess brown fat is now accepted — but is the brown fat metabolically active? Does human brown fat actually combust fat to release heat? In this issue of the JCI, Ouellet et al. demonstrate that metabolism in brown fat really is increased when adult humans are exposed to cold. This boosts the possibility that calorie combustion in brown fat may be of significance for our metabolism and, correspondingly, that the absence of brown fat may increase our proneness to obesity — provided that brown fat becomes activated not only by cold but also through food-related stimuli.

Authors

Barbara Cannon, Jan Nedergaard

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Total citations by year

Year: 2025 2023 2022 2021 2020 2018 2016 2015 2014 2013 2012 Total
Citations: 1 4 5 1 2 3 2 3 3 2 2 28
Citation information
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Citations to this article (28)

Title and authors Publication Year
Adipokines as Cardioprotective Factors: BAT Steps Up to the Plate
McLeod K, Datta V, Fuller S
Biomedicines 2025
Neuro-Vulnerability in Energy Metabolism Regulation: A Comprehensive Narrative Review
Clemente-Suárez VJ, Beltrán-Velasco AI, Redondo-Flórez L, Martín-Rodríguez A, Yáñez-Sepúlveda R, Tornero-Aguilera JF
Nutrients 2023
Determination of the Effects of a Series of Ten Whole-Body Cryostimulation Sessions on Physiological Responses to Exercise and Skin Temperature Behavior following Exercise in Elite Athletes
Pokora I, Drzazga Z, Wyderka P, Binek M
Journal of Clinical Medicine 2023
Absolute thermometry of human brown adipose tissue by magnetic resonance with laser polarized 129Xe
Zhang L, Antonacci M, Burant A, McCallister A, Kelley M, Bryden N, McHugh C, Atalla S, Holmes L, Katz L, Branca RT
2023
A century of exercise physiology: concepts that ignited the study of human thermoregulation. Part 3: Heat and cold tolerance during exercise.
Notley SR, Mitchell D, Taylor NAS
European Journal of Applied Physiology 2023
Brown adipose tissue thermogenesis among a small sample of reindeer herders from sub-Arctic Finland
C Ocobock, P Soppela, M Turunen, V Stenbäck, K Herzig
Journal of PHYSIOLOGICAL ANTHROPOLOGY 2022
Brown Adipose Tissue and Novel Management Strategies for Polycystic Ovary Syndrome Therapy
Zhang Q, Ye R, Zhang YY, Fan CC, Wang J, Wang S, Chen S, Liu X
Frontiers in Endocrinology 2022
No association of BMI and body adiposity with cardiometabolic biomarkers among a small sample of reindeer herders of sub-Arctic Finland
Ocobock C, Soppela P, Turunen MT
International Journal of Circumpolar Health 2022
The Effect of Repetitive Whole Body Cryotherapy Treatment on Adaptations to a Strength and Endurance Training Programme in Physically Active Males
Haq A, Ribbans WJ, Hohenauer E, Baross AW
2022
In vivo imaging of brown adipose tissue vasculature reactivity during adrenergic stimulation of non-shivering thermogenesis in mice
Garside JC, Livingston EW, Frank JE, Yuan H, Branca RT
Scientific Reports 2022
Adaptive thermogenesis in brown adipose tissue involves activation of pannexin-1 channels
S Senthivinayagam, V Serbulea, CM Upchurch, R Polanowska-Grabowska, SK Mendu, S Sahu, P Jayaguru, KW Aylor, MD Chordia, L Steinberg, N Oberholtzer, S Uchiyama, N Inada, UM Lorenz, TE Harris, SR Keller, AK Meher, A Kadl, BN Desai, BK Kundu, N Leitinger
Molecular Metabolism 2021
Control of Adipose Cell Browning and Its Therapeutic Potential
F Lizcano, F Arroyave
Metabolites 2020
Dopamine receptor D1- and D2-agonists do not spark brown adipose tissue thermogenesis in mice
FM Raffaelli, J Resch, R Oelkrug, KA Iwen, J Mittag
Scientific Reports 2020
Effect of Iodothyronines on Thermogenesis: Focus on Brown Adipose Tissue
F Cioffi, A Gentile, E Silvestri, F Goglia, A Lombardi
Frontiers in Endocrinology 2018
Role of Cannabinoids in Obesity
F Rossi, F Punzo, G Umano, M Argenziano, EM Giudice
International journal of molecular sciences 2018
Recent advances in our understanding of brown and beige adipose tissue: the good fat that keeps you healthy
ME Symonds, P Aldiss, M Pope, H Budge
F1000Research 2018
Contributors to Metabolic Disease Risk Following Spinal Cord Injury
DL Smith, C Yarar-Fisher
Current Physical Medicine and Rehabilitation Reports 2016
Effects of pterostilbene in brown adipose tissue from obese rats
L Aguirre, I Milton-Laskibar, E Hijona, L Bujanda, AM Rimando, MP Portillo
Journal of Physiology and Biochemistry 2016
3,5-Diiodo-L-Thyronine Activates Brown Adipose Tissue Thermogenesis in Hypothyroid Rats
A Lombardi, R Senese, RD Matteis, RA Busiello, F Cioffi, F Goglia, A Lanni, M López
PloS one 2015
Direct conversion of human myoblasts into brown-like adipocytes by engineered super-active PPARγ: Conversion of Human Myoblasts to Brown-Like Adipocytes
Y Zhu, R Yang, J McLenithan, D Yu, H Wang, Y Wang, D Singh, J Olson, C Sztalryd, D Zhu, DW Gong
Obesity 2015
Can thermogenic adipocytes protect from obesity?
LN Medvedev, EI Elsukova
Journal of Physiology and Biochemistry 2015
Detection of brown adipose tissue and thermogenic activity in mice by hyperpolarized xenon MRI
RT Branca, T He, L Zhang, CS Floyd, M Freeman, C White, A Burant
Proceedings of the National Academy of Sciences 2014
MRI detection of brown adipose tissue with low fat content in newborns with hypothermia
HH Hu, TW Wu, L Yin, MS Kim, JM Chia, TG Perkins, V Gilsanz
Magnetic Resonance Imaging 2014
Shc depletion stimulates brown fat activity in vivo and in vitro
A Tomilov, A Bettaieb, K Kim, S Sahdeo, N Tomilova, A Lam, K Hagopian, M Connell, J Fong, D Rowland, S Griffey, J Ramsey, F Haj, G Cortopassi
Aging Cell 2014
Baseline tumor growth and immune control in laboratory mice are significantly influenced by subthermoneutral housing temperature
KM Kokolus, ML Capitano, CT Lee, JW Eng, JD Waight, BL Hylander, S Sexton, CC Hong, CJ Gordon, SI Abrams, EA Repasky
Proceedings of the National Academy of Sciences 2013
Evodiamine inhibits insulin-stimulated mTOR-S6K activation and IRS1 serine phosphorylation in adipocytes and improves glucose tolerance in obese/diabetic mice
T Wang, T Kusudo, T Takeuchi, Y Yamashita, Y Kontani, Y Okamatsu, M Saito, N Mori, H Yamashita
PloS one 2013
Sex differences in human adipose tissues – the biology of pear shape
K Karastergiou, SR Smith, AS Greenberg, SK Fried
Biology of sex differences 2012
Endothelial cells of adipose tissues
A Frontini, A Giordano, S Cinti
Cell cycle (Georgetown, Tex.) 2012

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