Citations to this article

Mommy — where do tumors come from?
Ervin H. Epstein Jr.
Ervin H. Epstein Jr.
Published April 25, 2011
Citation Information: J Clin Invest. 2011;121(5):1681-1683. https://doi.org/10.1172/JCI57700.
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Mommy — where do tumors come from?

Abstract

Identification of the cell of origin of cancers is a hot topic, and recently no fewer than five groups have addressed this question for basal cell carcinomas (BCCs) of the skin. In this issue of the JCI, Grachtchouk et al. present evidence from engineered mouse models that at least some BCCs can arise from hair follicle tissue stem cells. Although these cells sustain oncogenic mutations while in the stem cell niche, they may have to leave that stem cell niche to become tumor cells.

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Ervin H. Epstein Jr.

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Year: 2021 2015 2014 2013 2011 Total
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Citations to this article (6)

Title and authors Publication Year
A role for keratin 17 during DNA damage response and tumor initiation
Nair RR, Hsu J, Jacob JT, Pineda CM, Hobbs RP, Coulombe PA 		Proceedings of the National Academy of Sciences 2021
Basal Cell Carcinoma Preferentially Arises from Stem Cells within Hair Follicle and Mechanosensory Niches
SC Peterson, M Eberl, AN Vagnozzi, A Belkadi, NA Veniaminova, ME Verhaegen, CK Bichakjian, NL Ward, AA Dlugosz, SY Wong 		Cell Stem Cell 2015
Advanced treatment for basal cell carcinomas
SX Atwood, RJ Whitson, AE Oro 		Cold Spring Harbor Perspectives in Medicine 2014
Tracking cells in their native habitat: lineage tracing in epithelial neoplasia
MP Alcolea, PH Jones 		Nature Reviews Cancer 2013
"Patch"ing up our tumor signaling knowledge
SX Atwood, RJ Whitson, AE Oro 		Journal of Investigative Dermatology 2013
Tracing the roots of squamous cell carcinomas.
Nature Medicine 2011

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