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Eugene P. Rhee, … , Thomas J. Wang, Robert E. Gerszten
Published March 14, 2011
Citation Information: J Clin Invest. 2011;121(4):1402-1411. https://doi.org/10.1172/JCI44442.
Citation Information: J Clin Invest. 2011;121(4):1402-1411. https://doi.org/10.1172/JCI44442.
Abstract
Dyslipidemia is an independent risk factor for type 2 diabetes, although exactly which of the many plasma lipids contribute to this remains unclear. We therefore investigated whether lipid profiling can inform diabetes prediction by performing liquid chromatography/mass spectrometry–based lipid profiling in 189 individuals who developed type 2 diabetes and 189 matched disease-free individuals, with over 12 years of follow up in the Framingham Heart Study. We found that lipids of lower carbon number and double bond content were associated with an increased risk of diabetes, whereas lipids of higher carbon number and double bond content were associated with decreased risk. This pattern was strongest for triacylglycerols (TAGs) and persisted after multivariable adjustment for age, sex, BMI, fasting glucose, fasting insulin, total triglycerides, and HDL cholesterol. A combination of 2 TAGs further improved diabetes prediction. To explore potential mechanisms that modulate the distribution of plasma lipids, we performed lipid profiling during oral glucose tolerance testing, pharmacologic interventions, and acute exercise testing. Levels of TAGs associated with increased risk for diabetes decreased in response to insulin action and were elevated in the setting of insulin resistance. Conversely, levels of TAGs associated with decreased diabetes risk rose in response to insulin and were poorly correlated with insulin resistance. These studies identify a relationship between lipid acyl chain content and diabetes risk and demonstrate how lipid profiling could aid in clinical risk assessment.
Authors
Eugene P. Rhee, Susan Cheng, Martin G. Larson, Geoffrey A. Walford, Gregory D. Lewis, Elizabeth McCabe, Elaine Yang, Laurie Farrell, Caroline S. Fox, Christopher J. O’Donnell, Steven A. Carr, Ramachandran S. Vasan, Jose C. Florez, Clary B. Clish, Thomas J. Wang, Robert E. Gerszten
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Citation information
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Eichelmann F, Sellem L, Wittenbecher C, Jäger S, Kuxhaus O, Prada M, Cuadrat R, Jackson KG, Lovegrove JA, Schulze MB |
Circulation | 2022 |
|
Lipidomics in Biomarker Research.
Hornemann T |
Handbook of experimental pharmacology | 2022 |
|
Plasma metabolite profiles related to plant-based diets and the risk of type 2 diabetes.
Wang F, Baden MY, Guasch-Ferré M, Wittenbecher C, Li J, Li Y, Wan Y, Bhupathiraju SN, Tobias DK, Clish CB, Mucci LA, Eliassen AH, Costenbader KH, Karlson EW, Ascherio A, Rimm EB, Manson JE, Liang L, Hu FB |
Diabetologia | 2022 |
|
Large-scale integrated analysis of genetics and metabolomic data reveals potential links between lipids and colorectal cancer risk
Shu X, Chen Z, Long J, Guo X, Yang Y, Qu C, Ahn YO, Cai Q, Casey G, Gruber SB, Huyghe JR, Jee SH, Jenkins MA, Jia WH, Jung KJ, Kamatani Y, Kim DH, Kim J, Kweon SS, Le Marchand L, Matsuda K, Matsuo K, Newcomb PA, Oh JH, Ose J, Oze I, Pai RK, Pan ZZ, Pharoah PD, Playdon MC, Ren ZF, Schoen RE, Shin A, Shin MH, Shu XO, Sun X, Tangen CM, Tanikawa C, Ulrich CM, van Duijnhoven FJ, Van Guelpen B, Wolk A, Woods MO, Wu AH, Peters U, Zheng W |
Cancer epidemiology, biomarkers & prevention | 2022 |
|
Impaired Amino Acid Metabolism and Its Correlation with Diabetic Kidney Disease Progression in Type 2 Diabetes Mellitus
Zhu H, Bai M, Xie X, Wang J, Weng C, Dai H, Chen J, Han F, Lin W |
Nutrients | 2022 |
|
Paternal low protein diet perturbs inter-generational metabolic homeostasis in a tissue-specific manner in mice.
Morgan HL, Furse S, Dias IHK, Shabir K, Castellanos M, Khan I, May ST, Holmes N, Carlile M, Sang F, Wright V, Koulman A, Watkins AJ |
2022 | |
|
Serum lipidomic determinants of human diabetic neuropathy in type 2 diabetes.
Afshinnia F, Reynolds EL, Rajendiran TM, Soni T, Byun J, Savelieff MG, Looker HC, Nelson RG, Michailidis G, Callaghan BC, Pennathur S, Feldman EL |
Annals of Clinical and Translational Neurology | 2022 |
|
Olive- and Coconut-Oil-Enriched Diets Decreased Secondary Bile Acids and Regulated Metabolic and Transcriptomic Markers of Brain Injury in the Frontal Cortexes of NAFLD Pigs
Maj MA, Gehani TR, Immoos C, Medrano MS, Fanter RK, Strand CR, Glanz H, Piccolo BD, Abo-Ismail MK, La Frano MR, Manjarín R |
Brain Sciences | 2022 |
|
Alterations in Microbiota and Metabolites Related to Spontaneous Diabetes and Pre-Diabetes in Rhesus Macaques
Jiang C, Pan X, Luo J, Liu X, Zhang L, Liu Y, Lei G, Hu G, Li J |
Genes & development | 2022 |
|
Huangshan Maofeng Green Tea Extracts Prevent Obesity-Associated Metabolic Disorders by Maintaining Homeostasis of Gut Microbiota and Hepatic Lipid Classes in Leptin Receptor Knockout Rats
Wu G, Gu W, Cheng H, Guo H, Li D, Xie Z |
Foods | 2022 |
|
Response of circulating metabolites to an oral glucose challenge and risk of cardiovascular disease and mortality in the community
Gonzalez Izundegui D, Miller PE, Shah RV, Clish CB, Walker ME, Mitchell GF, Gerszten RE, Larson MG, Vasan RS, Nayor M |
Cardiovascular Diabetology | 2022 |
|
Sex-specific changes in triglyceride profiles in liver cirrhosis and hepatitis C virus infection.
Peschel G, Grimm J, Müller M, Höring M, Krautbauer S, Weigand K, Liebisch G, Buechler C |
Lipids in Health and Disease | 2022 |
|
A Six-Week Follow-Up Study on the Sustained Effects of Prolonged Water-Only Fasting and Refeeding on Markers of Cardiometabolic Risk.
Gabriel S, Ncube M, Zeiler E, Thompson N, Karlsen MC, Goldman DM, Glavas Z, Beauchesne A, Scharf E, Goldhamer AC, Myers TR |
Nutrients | 2022 |
|
The Beneficial Effect of Cinnamon and Red Capsicum Intake on Postprandial Changes in Plasma Metabolites Evoked by a High-Carbohydrate Meal in Men with Overweight/Obesity.
Hameed A, Adamska-Patruno E, Godzien J, Czajkowski P, Miksza U, Pietrowska K, Fiedorczuk J, Moroz M, Bauer W, Sieminska J, Górska M, Krętowski AJ, Ciborowski M |
Nutrients | 2022 |
|
Specific triacylglycerol, diacylglycerol, and lyso-phosphatidylcholine species for the prediction of type 2 diabetes: a ~ 16-year prospective study in Chinese.
Zhong J, Cheung CYY, Su X, Lee CH, Ru Y, Fong CHY, Liu Y, Cheung CKY, Lam KSL, Cai Z, Xu A |
Cardiovascular Diabetology | 2022 |
|
Application of Metabolomics in Childhood Leukemia Diagnostics.
Kozioł A, Pupek M |
Archivum Immunologiae et Therapiae Experimentalis | 2022 |
|
Plasma Lipidomic Subclasses and Risk of Hypertension in Middle-Aged and Elderly Chinese
Niu Z, Wu Q, Luo Y, Wang D, Zheng H, Wu Y, Yang X, Zeng R, Sun L, Lin X |
2022 | |
|
Nontargeted and Targeted Metabolomic Profiling Reveals Novel Metabolite Biomarkers of Incident Diabetes in African Americans
Chen ZZ, Pacheco JA, Gao Y, Deng S, Peterson B, Shi X, Zheng S, Tahir UA, Katz DH, Cruz DE, Ngo D, Benson MD, Robbins JM, Guo X, del Rocio Sevilla Gonzalez M, Manning A, Correa A, Meigs JB, Taylor KD, Rich SS, Goodarzi MO, Rotter JI, Wilson JG, Clish CB, Gerszten RE |
Diabetes | 2022 |
|
Metabolic and Genetic Markers Improve Prediction of Incident Type 2 Diabetes: A Nested Case-Control Study in Chinese
Liu J, Wang L, Qian Y, Shen Q, Yang M, Dong Y, Chen H, Yang Z, Liu Y, Cui X, Ma H, Jin G |
The Journal of clinical endocrinology and metabolism | 2022 |
|
Metabolomics identifies shared lipid pathways in independent amyotrophic lateral sclerosis cohorts.
Goutman SA, Guo K, Savelieff MG, Patterson A, Sakowski SA, Habra H, Karnovsky A, Hur J, Feldman EL |
Brain : a journal of neurology | 2022 |
|
In Vitro Modeling of Diabetes Impact on Vascular Endothelium: Are Essentials Engaged to Tune Metabolism?
Vorotnikov AV, Khapchaev AY, Nickashin AV, Shirinsky VP |
Biomedicines | 2022 |
|
Gut Microbiota and Cardiovascular System: An Intricate Balance of Health and the Diseased State
Bhat MA, Mishra AK, Tantray JA, Alatawi HA, Saeed M, Rahman S, Jan AT |
Life Sciences | 2022 |
|
Metabolomics and Lipidomics Signatures of Insulin Resistance and Abdominal Fat Depots in People Living with Obesity.
Koay YC, Coster ACF, Chen DL, Milner B, Batarseh A, O'Sullivan JF, Greenfield JR, Samocha-Bonet D |
Metabolites | 2022 |
|
Change in fatty acid composition of plasma triglyceride caused by a 2 week comprehensive risk management for diabetes: A prospective observational study of type 2 diabetes patients with supercritical fluid chromatography/mass spectrometry‐based semi‐target lipidomic analysis
Taya N, Katakami N, Omori K, Hosoe S, Watanabe H, Takahara M, Miyashita K, Nishizawa H, Konya Y, Obara S, Hidaka A, Nakao M, Takahashi M, Izumi Y, Shimomura I, Bamba T |
Journal of Diabetes Investigation | 2022 |
|
Dairy Milk Casein and Whey Proteins Differentially Alter the Postprandial Lipidome in Persons with Prediabetes: A Comparative Lipidomics Study
Chen L, Xu R, McDonald JD, Bruno RS, Choueiry F, Zhu J |
Journal of Agricultural and Food Chemistry | 2022 |
|
Metabolic characterization of hypertrophic cardiomyopathy in human heart.
Wang W, Wang J, Yao K, Wang S, Nie M, Zhao Y, Wang B, Pang H, Xu J, Wu G, Lu M, Tang N, Qi C, Pei H, Luo X, Li D, Yang T, Sun Q, Wei X, Li Y, Jiang D, Li P, Song L, Hu Z |
Nature cardiovascular research | 2022 |
|
Proteomic Profiling Reveals Novel Biomarkers and Pathways in Type 2 Diabetes Risk
Debby Ngo, Mark D Benson, Jonathan Z. Long, Zsu-Zsu Chen, Ruiqi Wang, Anjali K Nath, Michelle J Keyes, Dongxiao Shen, Sumita Sinha, Eric Kuhn, Jordan Morningstar, Xu Shi, Bennet D. Peterson, Christopher Chan, Daniel H Katz, Usman A. Tahir, Laurie Farrell, Olle Melander, Jonathan D. Mosley, Steven A. Carr, Ramachandran Vasan, Martin G Larson, J. Gustav Smith, Thomas Wang, Qiong Yang, Robert Gerszten |
JCI Insight | 2021 |
|
Metabolomic profiling identifies complex lipid species and amino acid analogues associated with response to weight loss interventions
NA Bihlmeyer, LC Kwee, CB Clish, AA Deik, RE Gerszten, NJ Pagidipati, B Laferrère, LP Svetkey, CB Newgard, WE Kraus, SH Shah, V Sánchez-Margalet |
PloS one | 2021 |
|
Metabolomics and lipidomics in NAFLD: biomarkers and non-invasive diagnostic tests
M Masoodi, A Gastaldelli, T Hyötyläinen, E Arretxe, C Alonso, M Gaggini, J Brosnan, QM Anstee, O Millet, P Ortiz, JM Mato, JF Dufour, M Orešič |
Nature Reviews Gastroenterology & Hepatology | 2021 |
|
Renin-angiotensin system inhibition reverses the altered triacylglycerol metabolic network in diabetic kidney disease
KM Sas, J Lin, CH Wang, H Zhang, J Saha, TM Rajendiran, T Soni, V Nair, F Eichinger, M Kretzler, FC Brosius, G Michailidis, S Pennathur |
Metabolomics | 2021 |
|
Possible Gender Influence in the Mechanisms Underlying the Oxidative Stress, Inflammatory Response, and the Metabolic Alterations in Patients with Obesity and/or Type 2 Diabetes
ML Contreras-Zentella, R Hernández-Muñoz |
Antioxidants | 2021 |
|
Identification of Circulating Endocan-1 and Ether Phospholipids as Biomarkers for Complications in Thalassemia Patients
A Botta, A Forest, C Daneault, K Pantopoulos, A Tantiworawit, A Phrommintikul, S Chattipakorn, N Chattipakorn, CD Rosiers, G Sweeney |
Metabolites | 2021 |
|
Plasma Lipidomic Profiles and Risk of Diabetes: 2 Prospective Cohorts of HIV-Infected and HIV-Uninfected Individuals
E Zhang, JC Chai, AA Deik, S Hua, A Sharma, MF Schneider, D Gustafson, DB Hanna, JE Lake, LH Rubin, WS Post, K Anastos, T Brown, CB Clish, RC Kaplan, Q Qi |
The Journal of clinical endocrinology and metabolism | 2021 |
|
Metabolomics Insights into Osteoporosis Through Association With Bone Mineral Density
X Zhang, H Xu, GH Li, MT Long, CL Cheung, RS Vasan, YH Hsu, DP Kiel, CT Liu |
Journal of Bone and Mineral Research | 2021 |
|
Overview of Lipidomic Analysis of Triglyceride Molecular Species in Biological Lipid Extracts
X Han, H Ye |
Journal of Agricultural and Food Chemistry | 2021 |
|
Clinical and metabolomic predictors of regression to normoglycemia in a population at intermediate cardiometabolic risk
M del Rocío Sevilla-González, J Merino, H Moreno-Macias, R Rojas-Martínez, DV Gómez-Velasco, AK Manning |
Cardiovascular Diabetology | 2021 |
|
Metabolic profile distinguishes laminitis-susceptible and -resistant ponies before and after feeding a high sugar diet
J Delarocque, DB Reiche, AD Meier, T Warnken, K Feige, MN Sillence |
BMC veterinary research | 2021 |
|
A prospective study of maternal adiposity and glycemic traits across pregnancy and mid-childhood metabolomic profiles
ML Rahman, M Doyon, M Arguin, P Perron, L Bouchard, MF Hivert |
International Journal of Obesity | 2021 |
|
Predictive utilities of lipid traits, lipoprotein subfractions and other risk factors for incident diabetes: a machine learning approach in the Diabetes Prevention Program
TV Varga, J Liu, RB Goldberg, G Chen, S Dagogo-Jack, C Lorenzo, KJ Mather, X Pi-Sunyer, S Brunak, M Temprosa |
BMJ Open Diabetes Research & Care | 2021 |
|
Lipids: biomarkers of healthy aging
I Almeida, S Magalhães, A Nunes |
Biogerontology | 2021 |
|
Changes in Plasma Metabolome Profiles Following Oral Glucose Challenge among Adult Chinese
S Huo, L Sun, G Zong, X Shen, H Zheng, Q Jin, H Li, H Yin, X Lin |
Nutrients | 2021 |
|
Using lipid profiling to better characterize metabolic differences in apolipoprotein E (APOE) genotype among community-dwelling older Black men
MM Marron, SC Moore, SG Wendell, RM Boudreau, I Miljkovic, A Sekikawa, AB Newman |
GeroScience | 2021 |
|
Shorter Chain Triglycerides Are Negatively Associated with Symptom Improvement in Schizophrenia
A Tkachev, E Stekolshchikova, N Anikanov, S Zozulya, A Barkhatova, T Klyushnik, D Petrova |
Biomolecules | 2021 |
|
Plasma Metabolomic Signatures of Healthy Dietary Patterns in the Chronic Renal Insufficiency Cohort (CRIC) Study
H Kim, CA Anderson, EA Hu, Z Zheng, LJ Appel, J He, HI Feldman, AH Anderson, AC Ricardo, Z Bhat, TN Kelly, J Chen, RS Vasan, PL Kimmel, ME Grams, J Coresh, CB Clish, EP Rhee, CM Rebholz |
The Journal of nutrition | 2021 |
|
Metabolomics Signatures of Aging: Recent Advances
SS Adav, Y Wang |
Aging and disease | 2021 |
|
Differential Lipidomic Characteristics of Children Born to Women with Polycystic Ovary Syndrome
Z Zhang, Y Liu, J Lv, D Zhang, K Hu, J Li, J Ma, L Cui, H Zhao |
Frontiers in Endocrinology | 2021 |
|
In-depth triacylglycerol profiling using MS3 Q-Trap mass spectrometry
M Cabruja, J Priotti, P Domizi, K Papsdorf, DL Kroetz, A Brunet, K Contrepois, MP Snyder |
Analytica Chimica Acta | 2021 |
|
Prolactin and Risk of Epithelial Ovarian Cancer
CA Hathaway, MS Rice, MK Townsend, SE Hankinson, AA Arslan, JE Buring, G Hallmans, A Idahl, LD Kubzansky, IM Lee, EA Lundin, PM Sluss, A Zeleniuch-Jacquotte, SS Tworoger |
Cancer epidemiology, biomarkers & prevention | 2021 |
|
Emerging Applications of Metabolomics to Assess the Efficacy of Traditional Chinese Medicines for Treating Type 2 Diabetes Mellitus
Y Zhang, Y Yang, L Ding, Z Wang, Y Xiao, W Xiao |
Frontiers in pharmacology | 2021 |
|
Mouse lipidomics reveals inherent flexibility of a mammalian lipidome
MA Surma, MJ Gerl, R Herzog, J Helppi, K Simons, C Klose |
Scientific Reports | 2021 |
|
Intensive lactation among women with recent gestational diabetes significantly alters the early postpartum circulating lipid profile: the SWIFT study
Z Zhang, M Lai, AL Piro, SE Alexeeff, A Allalou, HL Röst, FF Dai, MB Wheeler, EP Gunderson |
BMC Medicine | 2021 |
|
Distinct Molecular Signatures of Clinical Clusters in People With Type 2 Diabetes: An IMI-RHAPSODY Study
RC Slieker, LA Donnelly, H Fitipaldi, GA Bouland, GN Giordano, M Åkerlund, MJ Gerl, E Ahlqvist, A Ali, I Dragan, P Elders, A Festa, MK Hansen, AA van der Heijden, DM Aly, M Kim, D Kuznetsov, F Mehl, C Klose, K Simons, I Pavo, TJ Pullen, T Suvitaival, A Wretlind, P Rossing, V Lyssenko, CL Quigley, L Groop, B Thorens, PW Franks, M Ibberson, GA Rutter, JW Beulens, LM t Hart, ER Pearson |
Diabetes | 2021 |
|
Cord Blood Metabolome and BMI Trajectory from Birth to Adolescence: A Prospective Birth Cohort Study on Early Life Biomarkers of Persistent Obesity
T Cao, J Zhao, X Hong, G Wang, FB Hu, X Wang, L Liang |
Metabolites | 2021 |
|
Genomics of Postprandial Lipidomics in the Genetics of Lipid-Lowering Drugs and Diet Network Study
MR Irvin, ME Montasser, T Kind, S Fan, DK Barupal, A Patki, RM Tanner, ND Armstrong, KA Ryan, SA Claas, JR OConnell, HK Tiwari, DK Arnett |
Nutrients | 2021 |
|
Fatty acids and their role in type‑2 diabetes (Review)
S Shetty, S Kumari |
Experimental and therapeutic medicine | 2021 |
|
Plasma lipidomics profile in pregnancy and gestational diabetes risk: a prospective study in a multiracial/ethnic cohort
ML Rahman, YC Feng, O Fiehn, PS Albert, MY Tsai, Y Zhu, X Wang, F Tekola-Ayele, L Liang, C Zhang |
BMJ Open Diabetes Research & Care | 2021 |
|
Longitudinal Plasma Lipidome and Risk of Type 2 Diabetes in a Large Sample of American Indians With Normal Fasting Glucose: The Strong Heart Family Study
G Miao, Y Zhang, Z Huo, W Zeng, J Zhu, JG Umans, G Wohlgemuth, D Pedrosa, B DeFelice, SA Cole, AM Fretts, ET Lee, BV Howard, O Fiehn, J Zhao |
Diabetes care | 2021 |
|
Plasma Metabolomics and Lipidomics Differentiate Obese Individuals by Peripheral Neuropathy Status
K Guo, M Savelieff, A Rumora, F Alakwaa, B Callaghan, J Hur, E Feldman |
The Journal of clinical endocrinology and metabolism | 2021 |
|
Revealing the Hypoglycemic Effects and Mechanism of GABA-Rich Germinated Adzuki Beans on T2DM Mice by Untargeted Serum Metabolomics
X Jiang, Q Xu, A Zhang, Y Liu, Z Li, H Tang, D Cao, D Zhang |
Frontiers in Nutrition | 2021 |
|
Lipidomics Reveals Serum Specific Lipid Alterations in Diabetic Nephropathy
Xu T, Xu X, Zhang L, Zhang K, Wei Q, Zhu L, Yu Y, Xiao L, Lin L, Qian W, Wang J, Ke M, An X, Liu S |
Frontiers in Endocrinology | 2021 |
|
Distinct Lipidomic Signatures in People Living With HIV: Combined Analysis of ACTG 5260s and MACS/WIHS
Jao J, Balmert LC, Sun S, McComsey GA, Brown TT, Tien PC, Currier JS, Stein JH, Qiu Y, LeRoith D, Kurland IJ |
The Journal of clinical endocrinology and metabolism | 2021 |
|
Changes in metabolomics profiles over ten years and subsequent risk of developing type 2 diabetes: Results from the Nurses' Health Study
Wittenbecher C, Guasch-Ferré M, Haslam DE, Dennis C, Li J, Bhupathiraju SN, Lee CH, Qi Q, Liang L, Eliassen AH, Clish C, Sun Q, Hu FB |
EBioMedicine | 2021 |
|
Human disease biomarker panels through systems biology
Smith BJ, Silva-Costa LC, Martins-de-Souza D |
Biophysical Reviews | 2021 |
|
Comparative Analysis of the Effects of Fish Oil and Fenofibrate on Plasma Metabolomic Profiles in Overweight and Obese Individuals
Michielsen CC, Hangelbroek RW, Bragt MC, Verheij ER, Wopereis S, Mensink RP, Afman LA |
Molecular Nutrition & Food Research | 2021 |
|
Insights into genetic variants associated with NASH-fibrosis from metabolite profiling
JP Mann, M Pietzner, LB Wittemans, ED Rolfe, ND Kerrison, F Imamura, NG Forouhi, E Fauman, ME Allison, JL Griffin, A Koulman, NJ Wareham, C Langenberg |
Human Molecular Genetics | 2020 |
|
Sphingolipid Mediators of Myocardial Pathology
A Kovilakath, LA Cowart |
Journal of Lipid and Atherosclerosis | 2020 |
|
Metabolic Architecture of Acute Exercise Response in Middle-Aged Adults in the Community
M Nayor, RV Shah, PE Miller, JB Blodgett, M Tanguay, AR Pico, VL Murthy, R Malhotra, NE Houstis, A Deik, KA Pierce, K Bullock, L Dailey, RS Velagaleti, SA Moore, JE Ho, AL Baggish, CB Clish, MG Larson, RS Vasan, GD Lewis |
Circulation | 2020 |
|
Mitochondrial Dysfunction, Insulin Resistance, and Potential Genetic Implications
P Sangwung, KF Petersen, GI Shulman, JW Knowles |
Endocrinology | 2020 |
|
Association of Apolipoprotein e2 Allele with Insulin Resistance and Risk of Type 2 Diabetes Mellitus Among an Admixed Population of Mexico K Gonzalez-Aldaco, S Roman, LA Torres-Reyes, A Panduro |
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy | 2020 |
|
Regulatory Connections between Iron and Glucose Metabolism
C Fillebeen, NH Lam, S Chow, A Botta, G Sweeney, K Pantopoulos |
International journal of molecular sciences | 2020 |
|
Dairy Intake in 2 American Adult Cohorts Associates with Novel and Known Targeted and Nontargeted Circulating Metabolites
A Hruby, C Dennis, PF Jacques |
The Journal of nutrition | 2020 |
|
Lipidomic profiling identifies signatures of metabolic risk
X Yin, CM Willinger, J Keefe, J Liu, A Fernández-Ortiz, B Ibáñez, J Peñalvo, A Adourian, G Chen, D Corella, R Pamplona, M Portero-Otin, M Jove, P Courchesne, CM van Duijn, V Fuster, JM Ordovás, A Demirkan, MG Larson, D Levy |
EBioMedicine | 2020 |
|
Metabolites Associated with Walking Ability Among the Oldest Old from the CHS All Stars Study
MM Marron, SG Wendell, RM Boudreau, CB Clish, AJ Santanasto, GC Tseng, JM Zmuda, AB Newman, D Melzer |
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences | 2020 |
|
Characterisation of the dynamic nature of lipids throughout the lifespan of genetically identical female and male Daphnia magna
JK Constantinou, AD Southam, J Kvist, MR Jones, MR Viant, L Mirbahai |
Scientific Reports | 2020 |
|
Lifetime Average Cannabis Use in Relation to Hypertriglyceridemic Waist Phenotype in U.S. Adults: A Population-Based Cross-Sectional Study
G Ngueta |
Cannabis and Cannabinoid Research | 2020 |
|
The Gut Microbial Diversity of Newly Diagnosed Diabetics but Not of Prediabetics Is Significantly Different from That of Healthy Nondiabetics
AH Gaike, D Paul, S Bhute, DP Dhotre, P Pande, S Upadhyaya, Y Reddy, R Sampath, D Ghosh, D Chandraprabha, J Acharya, G Banerjee, VP Sinkar, SS Ghaskadbi, YS Shouche, KL Whiteson |
mSystems | 2020 |
|
Serum sphingolipids and incident diabetes in a US population with high diabetes burden: the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)
GC Chen, JC Chai, B Yu, GA Michelotti, ML Grove, AM Fretts, ML Daviglus, OL Garcia-Bedoya, B Thyagarajan, N Schneiderman, J Cai, RC Kaplan, E Boerwinkle, Q Qi |
The American journal of clinical nutrition | 2020 |
|
Metabolic characterisation of disturbances in the APOC3/triglyceride-rich lipoprotein pathway through sample-based recall by genotype
LJ Corbin, DA Hughes, AJ Chetwynd, AE Taylor, AD Southam, A Jankevics, RJ Weber, A Groom, WB Dunn, NJ Timpson |
Metabolomics | 2020 |
|
Metabolic signatures associated with Western and Prudent dietary patterns in women
PD Chandler, R Balasubramanian, N Paynter, F Giulianini, T Fung, LF Tinker, L Snetselaar, S Liu, C Eaton, DK Tobias, FK Tabung, JA Manson, EL Giovannucci, C Clish, KM Rexrode |
The American journal of clinical nutrition | 2020 |
|
Proteomic and Metabolomic Correlates of Healthy Dietary Patterns: The Framingham Heart Study
ME Walker, RJ Song, X Xu, RE Gerszten, D Ngo, CB Clish, L Corlin, J Ma, V Xanthakis, PF Jacques, RS Vasan |
Nutrients | 2020 |
|
A lipidome-wide association study of the lipoprotein insulin resistance index
M Bagheri, HK Tiwari, AL Murillo, R Al-Tobasei, DK Arnett, T Kind, DK Barupal, S Fan, O Fiehn, J Oconnell, M Montasser, S Aslibekyan, MR Irvin |
Lipids in Health and Disease | 2020 |
|
Review of methods for detecting glycemic disorders
M Bergman, M Abdul-Ghani, RA DeFronzo, M Manco, G Sesti, TV Fiorentino, A Ceriello, M Rhee, LS Phillips, S Chung, C Cravalho, R Jagannathan, L Monnier, C Colette, D Owens, C Bianchi, S del Prato, MP Monteiro, JS Neves, JL Medina, MP Macedo, RT Ribeiro, JF Raposo, B Dorcely, N Ibrahim, M Buysschaert |
Diabetes Research and Clinical Practice | 2020 |
|
Altered Metabolome of Lipids and Amino Acids Species: A Source of Early Signature Biomarkers of T2DM
A Hameed, P Mojsak, A Buczynska, HA Suleria, A Kretowski, M Ciborowski |
Journal of Clinical Medicine | 2020 |
|
Underlying dyslipidemia postpartum in women with a recent GDM pregnancy who develop type 2 diabetes
M Lai, DA Rijjal, HL Röst, FF Dai, EP Gunderson, MB Wheeler |
eLife | 2020 |
|
Associations of depression status with plasma levels of candidate lipid and amino acid metabolites: a meta-analysis of individual data from three independent samples of US postmenopausal women
T Huang, R Balasubramanian, Y Yao, CB Clish, AH Shadyab, B Liu, SS Tworoger, KM Rexrode, JA Manson, LD Kubzansky, SE Hankinson |
Molecular Psychiatry | 2020 |
|
Metabolomics reveals the impact of Type 2 diabetes on local muscle and vascular responses to ischemic stress
JA Beckman, JR Hu, S Huang, E Farber-Eger, QS Wells, TJ Wang, RE Gerszten, JF Ferguson |
Clinical Science | 2020 |
|
Metabolomic signatures of cardiac remodelling and heart failure risk in the community
C Andersson, C Liu, S Cheng, TJ Wang, RE Gerszten, MG Larson, RS Vasan |
ESC Heart Failure | 2020 |
|
The metabolic footprint of compromised insulin sensitivity under fasting and hyperinsulinemic-euglycemic clamp conditions in an Arab population
A Halama, NN Suleiman, M Kulinski, I Bettahi, S Hassoun, M Alkasem, I Abdalhakam, A Iskandarani, TA Samra, SL Atkin, K Suhre, AB Abou-Samra |
Scientific Reports | 2020 |
|
Postpartum plasma metabolomic profile among women with preeclampsia and preterm delivery: implications for long-term health
X Hong, B Zhang, L Liang, Y Zhang, Y Ji, G Wang, H Ji, CB Clish, I Burd, C Pearson, B Zuckerman, FB Hu, X Wang |
BMC Medicine | 2020 |
|
Label-free CARS microscopy reveals similar triacylglycerol acyl chain length and saturation in myocellular lipid droplets of athletes and individuals with type 2 diabetes
S Daemen, A Gemmink, A Paul, N Billecke, K Rieger, SH Parekh, MK Hesselink |
Diabetologia | 2020 |
|
A lipid-related metabolomic pattern of diet quality
M Bagheri, W Willett, MK Townsend, P Kraft, KL Ivey, EB Rimm, KM Wilson, KH Costenbader, EW Karlson, EM Poole, OA Zeleznik, AH Eliassen |
The American journal of clinical nutrition | 2020 |
|
Association Between Circulating Lipids and Future Weight Gain in Individuals With an At-Risk Mental State and in First-Episode Psychosis
S Lamichhane, AM Dickens, P Sen, H Laurikainen, F Borgan, J Suvisaari, T Hyötyläinen, O Howes, J Hietala, M Orešič |
Schizophrenia Bulletin | 2020 |
|
The impact of ageing on lipid-mediated regulation of adult stem cell behavior and tissue homeostasis
RS Demarco, M Clémot, DL Jones |
Mechanisms of Ageing and Development | 2020 |
|
Dysregulated FXR-FGF19 signaling and choline metabolism are associated with gut dysbiosis and hyperplasia in a novel pig model of pediatric NASH
GV Hernandez, VA Smith, M Melnyk, MA Burd, KA Sprayberry, MS Edwards, DG Peterson, DC Bennet, RK Fanter, DA Columbus, JP Steibel, H Glanz, C Immoos, MS Rice, TM Santiago-Rodriguez, J Blank, JJ VanderKelen, CL Kitts, BD Piccolo, MR Frano, DG Burrin, Magdalena, R Manjarin |
AJP Gastrointestinal and Liver Physiology | 2020 |
|
Lipidomics investigations into the tissue phospholipidomic landscape of invasive ductal carcinoma of the breast
Taware R, More TH, Bagadi M, Taunk K, Mane A, Rapole S |
RSC Advances | 2020 |
|
Metabolomics and Proteomics in Type 2 Diabetes.
Chen ZZ, Gerszten RE |
Circulation research | 2020 |
|
SGLT2 inhibition reprograms systemic metabolism via FGF21-dependent and independent mechanisms
Soravis Osataphan, Chiara Macchi, Garima Singhal, Jeremy Chimene-Weiss, Vicencia M. Sales, Chisayo Kozuka, Hui Pan, Yanin Tangjaroenpaisan, Jordan E. Morningstar, Jonathan M Dreyfuss, Robert E. Gerszten, Mary Elizabeth Patti |
JCI Insight | 2019 |
|
High protein feeding induces de novo lipogenesis in healthy humans
Evelina Charidemou, Tom Ashmore, Xuefei Li, Ben D McNally, James West, Sonia Liggi, Matthew Harvey, Elise R Orford, Julian L. Griffin |
JCI Insight | 2019 |
|
Increased lipogenesis and impaired beta-oxidation predict type 2 diabetic kidney disease progression in American Indians
Farsad Afshinnia, Viji Nair, Jiahe Lin, Thekkelnaycke Rajendiran, Tanu Soni, Jaeman Byun, Kumar Sharma, Patrice Fort, Thomas Gardner, Helen C. Looker, Robert Nelson, Frank C. Brosius, Eva L. Feldman, George Michailidis, Matthias Kretzler, Subramaniam Pennathur |
JCI Insight | 2019 |
|
Roux-en-Y gastric bypass surgery reprograms enterocyte triglyceride metabolism and postprandial secretion in rats
S Kaufman, M Arnold, AA Diaz, H Neubauer, S Wolfrum, H Köfeler, W Langhans, JP Krieger |
Molecular Metabolism | 2019 |
|
Sex, gut microbiome, and cardiovascular disease risk
AC Razavi, KS Potts, TN Kelly, LA Bazzano |
Biology of sex differences | 2019 |
|
Detection of Secondary Metabolites as Biomarkers for the Early Diagnosis and Prevention of Type 2 Diabetes JY Al-Aama, HB Mahdi, MA Salama, KH Bakur, A Alhozali, HH Mosli, SM Bahijri, A Bahieldin, L Willmitzer, S Edris |
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy | 2019 |
|
Lipid Profiling Reveals Browning Heterogeneity of White Adipose Tissue by Β3-Adrenergic Stimulation
P He, B Hou, Y Li, C Xu, P Ma, SM Lam, V Gil, X Yang, X Yang, L Zhang, G Shui, J Song, G Qiang, CW Liew, G Du |
Biomolecules | 2019 |
|
Cold-induced lipid dynamics and transcriptional programs in white adipose tissue
Z Xu, W You, Y Zhou, W Chen, Y Wang, T Shan |
BMC Biology | 2019 |
|
Polyunsaturated Fatty Acid Desaturation Is a Mechanism for Glycolytic NAD+ Recycling
W Kim, A Deik, C Gonzalez, ME Gonzalez, F Fu, M Ferrari, CL Churchhouse, JC Florez, SB Jacobs, CB Clish, EP Rhee |
Cell Metabolism | 2019 |
|
Plasma metabolites predict both insulin resistance and incident type 2 diabetes: a metabolomics approach within the Prevención con Dieta Mediterránea (PREDIMED) study
C Papandreou, M Bulló, M Ruiz-Canela, C Dennis, A Deik, D Wang, M Guasch-Ferré, E Yu, C Razquin, D Corella, R Estruch, E Ros, M Fitó, M Fiol, L Liang, P Hernández-Alonso, CB Clish, MA Martínez-González, FB Hu, J Salas-Salvadó |
The American journal of clinical nutrition | 2019 |
|
Repeated administration of the NSAID meloxicam alters the plasma and urine lipidome
SM Rivera-Velez, LE Broughton-Neiswanger, M Suarez, P Piñeyro, J Navas, S Chen, J Hwang, NF Villarino |
Scientific Reports | 2019 |
|
Lipidome Abnormalities and Cardiovascular Disease Risk in HIV Infection
E Bowman, NT Funderburg |
Current HIV/AIDS Reports | 2019 |
|
A Slow-Digesting Carbohydrate Diet during Rat Pregnancy Protects Offspring from Non-Alcoholic Fatty Liver Disease Risk through the Modulation of the Carbohydrate-Response Element and Sterol Regulatory Element Binding Proteins
R Salto, M Manzano, MD Girón, A Cano, A Castro, JD Vílchez, E Cabrera, JM López-Pedrosa |
Nutrients | 2019 |
|
Maternal triacylglycerol signature and risk of food allergy in offspring
X Hong, L Liang, Q Sun, CA Keet, HJ Tsai, Y Ji, G Wang, H Ji, C Clish, C Pearson, Y Wang, RA Wood, FB Hu, X Wang |
Journal of Allergy and Clinical Immunology | 2019 |
|
Metabolomics of Type 1 and Type 2 Diabetes
B Arneth, R Arneth, M Shams |
International journal of molecular sciences | 2019 |
|
Circulating Saturated Fatty Acids and Incident Type 2 Diabetes: A Systematic Review and Meta-Analysis
Huang, Lin, Aris, Yang, Chen, Li |
Nutrients | 2019 |
|
New insights into the mechanisms of diabetic complications: role of lipids and lipid metabolism
S Eid, KM Sas, SF Abcouwer, EL Feldman, TW Gardner, S Pennathur, PE Fort |
Diabetologia | 2019 |
|
Serum untargeted lipidomic profiling reveals dysfunction of phospholipid metabolism in subclinical coronary artery disease D Djekic, R Pinto, D Repsilber, T Hyotylainen, M Henein |
Vascular Health and Risk Management | 2019 |
|
Identifying Metabolomic Profiles of Insulinemic Dietary Patterns
FK Tabung, R Balasubramanian, L Liang, SK Clinton, EM Feliciano, JA Manson, LV Horn, J Wactawski-Wende, CB Clish, EL Giovannucci, KM Rexrode |
Metabolites | 2019 |
|
Genetic architecture of human plasma lipidome and its link to cardiovascular disease
R Tabassum, JT Rämö, P Ripatti, JT Koskela, M Kurki, J Karjalainen, P Palta, S Hassan, J Nunez-Fontarnau, TT Kiiskinen, S Söderlund, N Matikainen, MJ Gerl, MA Surma, C Klose, NO Stitziel, H Laivuori, AS Havulinna, SK Service, V Salomaa, M Pirinen, M Jauhiainen, MJ Daly, NB Freimer, A Palotie, MR Taskinen, K Simons, S Ripatti |
Nature Communications | 2019 |
|
Using metabolite profiling to construct and validate a metabolite risk score for predicting future weight gain
N Geidenstam, YH Hsu, CM Astley, JM Mercader, M Ridderstråle, ME Gonzalez, C Gonzalez, JN Hirschhorn, RM Salem, RD Clugston |
PloS one | 2019 |
|
Metabolome-Wide Association Study of the Relationship Between Habitual Physical Activity and Plasma Metabolite Levels
M Ding, OA Zeleznik, M Guasch-Ferre, J Hu, J Lasky-Su, IM Lee, RD Jackson, AH Shadyab, MJ LaMonte, C Clish, AH Eliassen, F Sacks, WC Willett, FB Hu, KM Rexrode, P Kraft |
American Journal of Epidemiology | 2019 |
|
Plasma metabolites associated with homeostatic model assessment of insulin resistance: metabolite-model design and external validation
P Hernández-Alonso, J García-Gavilán, L Camacho-Barcia, A Sjödin, TT Hansen, J Harrold, J Salas-Salvadó, JC Halford, S Canudas, M Bulló |
Scientific Reports | 2019 |
|
n-3 PUFA and caloric restriction diet alters lipidomic profiles in obese men with metabolic syndrome: a preliminary open study
A Shabrina, TH Tung, NT Nguyen, HC Lee, HT Wu, W Wang, SY Huang |
European Journal of Nutrition | 2019 |
|
Identifying metabolomic profiles of inflammatory diets in postmenopausal women
FK Tabung, L Liang, T Huang, R Balasubramanian, Y Zhao, PD Chandler, JA Manson, EM Feliciano, KM Hayden, LV Horn, CB Clish, EL Giovannucci, KM Rexrode |
Clinical nutrition (Edinburgh, Scotland) | 2019 |
|
Altered triglyceride and phospholipid metabolism predates the diagnosis of gestational diabetes in obese pregnancy
S Furse, SL White, CL Meek, B Jenkins, CJ Petry, MC Vieira, SE Ozanne, DB Dunger, L Poston, A Koulman |
2019 | |
|
Identification of 102 Correlations between Serum Metabolites and Habitual Diet in a Metabolomics Study of the Prostate, Lung, Colorectal, and Ovarian Cancer Trial
KM Mazzilli, KM McClain, L Lipworth, MC Playdon, JN Sampson, CB Clish, RE Gerszten, ND Freedman, SC Moore |
The Journal of nutrition | 2019 |
|
Metabolite Profiles of Incident Diabetes and Heterogeneity of Treatment Effect in the Diabetes Prevention Program
ZZ Chen, J Liu, J Morningstar, BM Heckman-Stoddard, CG Lee, S Dagogo-Jack, JF Ferguson, RF Hamman, WC Knowler, KJ Mather, L Perreault, JC Florez, TJ Wang, C Clish, M Temprosa, RE Gerszten |
Diabetes | 2019 |
|
Lipidomics as a tool of predicting progression from non-alcoholic fatty pancreas disease to type 2 diabetes mellitus
Lin M, Weng SY, Chai KF, Mao ZJ |
RSC Advances | 2019 |
|
Inducible podocyte-specific deletion of CTCF drives progressive kidney disease and bone abnormalities
Marta Christov, Abbe Clark, Braden Corbin, Samy Hakroush, Eugene Rhee, Hiroaki Saito, Daniel Brooks, Eric Hesse, Mary Bouxsein, Niels Galjart, Ji Yong Jung, Peter Mundel, Harald Jüppner, Astrid Weins, Anna Greka |
JCI Insight | 2018 |
|
The circulating metabolome of human starvation
Matthew Steinhauser, Benjamin Olenchock, John O'Keefe, Mingyue Lun, Kerry Pierce, Hang Lee, Lorena Pantano, Anne Klibanski, Gerald I. Shulman, Clary Clish, Pouneh Fazeli |
JCI Insight | 2018 |
|
Diet, Genetics, and the Gut Microbiome Drive Dynamic Changes in Plasma Metabolites
S Fujisaka, J Avila-Pacheco, M Soto, A Kostic, JM Dreyfuss, H Pan, S Ussar, E Altindis, N Li, L Bry, CB Clish, CR Kahn |
Cell Reports | 2018 |
|
Hepatic steatosis risk is partly driven by increased de novo lipogenesis following carbohydrate consumption
FW Sanders, A Acharjee, C Walker, L Marney, LD Roberts, F Imamura, B Jenkins, J Case, S Ray, S Virtue, A Vidal-Puig, D Kuh, R Hardy, M Allison, N Forouhi, AJ Murray, N Wareham, M Vacca, A Koulman, JL Griffin |
Genome biology | 2018 |
|
Characterization of different fat depots in NAFLD using inflammation-associated proteome, lipidome and metabolome
A Lovric, M Granér, E Bjornson, M Arif, R Benfeitas, K Nyman, M Ståhlman, MO Pentikäinen, J Lundbom, A Hakkarainen, R Sirén, MS Nieminen, N Lundbom, K Lauerma, MR Taskinen, A Mardinoglu, J Boren |
Scientific Reports | 2018 |
|
Plasma lipidome patterns associated with cardiovascular risk in the PREDIMED trial: A case-cohort study
C Razquin, L Liang, E Toledo, CB Clish, M Ruiz-Canela, Y Zheng, DD Wang, D Corella, O Castaner, E Ros, F Aros, E Gomez-Gracia, M Fiol, JM Santos-Lozano, M Guasch-Ferre, L Serra-Majem, A Sala-Vila, P Buil-Cosiales, M Bullo, M Fito, O Portoles, R Estruch, J Salas-Salvado, FB Hu, MA Martinez-Gonzalez |
International Journal of Cardiology | 2018 |
|
Metabolomics insights into early type 2 diabetes pathogenesis and detection in individuals with normal fasting glucose
J Merino, A Leong, CT Liu, B Porneala, GA Walford, M Grotthuss, TJ Wang, J Flannick, J Dupuis, D Levy, RE Gerszten, JC Florez, JB Meigs |
Diabetologia | 2018 |
|
Development of A High Coverage Pseudotargeted Lipidomics Method Based on Ultra-High Performance Liquid Chromatography-Mass Spectrometry
Q Xuan, C Hu, D Yu, L Wang, Y Zhou, X Zhao, Q Li, X Hou, G Xu |
Analytical Chemistry | 2018 |
|
Metabolomics Identifies Distinctive Metabolite Signatures for Measures of Glucose Homeostasis: The Insulin Resistance Atherosclerosis Family Study (IRAS-FS)
ND Palmer, H Okut, FC Hsu, MC Ng, YD Chen, MO Goodarzi, KD Taylor, JM Norris, C Lorenzo, JI Rotter, RN Bergman, CD Langefeld, LE Wagenknecht, DW Bowden |
The Journal of clinical endocrinology and metabolism | 2018 |
|
Metabolomics signatures associated with an oral glucose challenge in pregnant women
B Gelaye, CB Clish, M Denis, G Larrabure, MG Tadesse, A Deik, K Pierce, K Bullock, C Dennis, DA Enquobahrie, MA Williams |
Diabetes & Metabolism | 2018 |
|
Lipidomics and Biomarker Discovery in Kidney Disease
F Afshinnia, TM Rajendiran, S Wernisch, T Soni, A Jadoon, A Karnovsky, G Michailidis, S Pennathur |
Seminars in Nephrology | 2018 |
|
Prioritising Risk Factors for Type 2 Diabetes: Causal Inference through Genetic Approaches
LB Wittemans, LA Lotta, C Langenberg |
Current Diabetes Reports | 2018 |
|
MicroRNA, Proteins, and Metabolites as Novel Biomarkers for Prediabetes, Diabetes, and Related Complications
S Vaishya, RD Sarwade, V Seshadri |
Frontiers in Endocrinology | 2018 |
|
Effects of aging on serum levels of lipid molecular species as determined by lipidomics analysis in Japanese men and women
N Kawanishi, Y Kato, K Yokozeki, S Sawada, R Sakurai, Y Fujiwara, S Shinkai, N Goda, K Suzuki |
Lipids in Health and Disease | 2018 |
|
Redefining environmental exposure for disease etiology
SM Rappaport |
npj Systems Biology and Applications | 2018 |
|
Clusters of fatty acids in the serum triacylglyceride fraction associate with the disorders of type 2 diabetes
LW Johnston, Z Liu, R Retnakaran, B Zinman, A Giacca, SB Harris, RP Bazinet, AJ Hanley |
Journal of lipid research | 2018 |
|
Associations between the maternal circulating lipid profile in pregnancy and fetal imprinted gene alleles: a cohort study
CJ Petry, A Koulman, L Lu, B Jenkins, S Furse, P Prentice, L Matthews, IA Hughes, CL Acerini, KK Ong, DB Dunger |
Reproductive Biology and Endocrinology | 2018 |
|
Genetic Regulation of Plasma Lipid Species and Their Association with Metabolic Phenotypes
P Jha, MT McDevitt, E Halilbasic, EG Williams, PM Quiros, K Gariani, MB Sleiman, R Gupta, A Ulbrich, A Jochem, JJ Coon, M Trauner, DJ Pagliarini, J Auwerx |
Cell Systems | 2018 |
|
Targeted lipidomics analysis identified altered serum lipid profiles in patients with polymyositis and dermatomyositis
J Raouf, H Idborg, P Englund, H Alexanderson, M Dastmalchi, PJ Jakobsson, IE Lundberg, M Korotkova |
Arthritis Research & Therapy | 2018 |
|
Targeted Metabolomics to Understand the Association between Arsenic Metabolism and Diabetes-Related Outcomes: Preliminary Evidence from the Strong Heart Family Study
MJ Spratlen, M Grau-Perez, JG Umans, J Yracheta, LG Best, K Francesconi, W Goessler, T Bottiglieri, MV Gamble, SA Cole, J Zhao, A Navas-Acien |
Environmental Research | 2018 |
|
Habitual sleep quality, plasma metabolites and risk of coronary heart disease in post-menopausal women
T Huang, OA Zeleznik, EM Poole, CB Clish, AA Deik, JM Scott, C Vetter, ES Schernhammer, R Brunner, L Hale, JA Manson, FB Hu, S Redline, SS Tworoger, KM Rexrode |
International Journal of Epidemiology | 2018 |
|
The relationship between phospholipids and insulin resistance: From clinical to experimental studies
W Chang, GM Hatch, Y Wang, F Yu, M Wang |
Journal of Cellular and Molecular Medicine | 2018 |
|
Plasma Lipidomic Profiling and Risk of Type 2 Diabetes in the PREDIMED Trial
C Razquin, E Toledo, CB Clish, M Ruiz-Canela, C Dennis, D Corella, C Papandreou, E Ros, R Estruch, M Guasch-Ferré, E Gómez-Gracia, M Fitó, E Yu, J Lapetra, D Wang, D Romaguera, L Liang, A Alonso-Gómez, A Deik, M Bullo, L Serra-Majem, J Salas-Salvadó, FB Hu, MA Martínez-González |
Diabetes care | 2018 |
|
Variability of Two Metabolomic Platforms in CKD
EP Rhee, SS Waikar, CM Rebholz, Z Zheng, R Perichon, CB Clish, AM Evans, J Avila, MR Denburg, AH Anderson, RS Vasan, HI Feldman, PL Kimmel, J Coresh |
Clinical journal of the American Society of Nephrology : CJASN | 2018 |
|
Plasma trimethylamine-N-oxide and related metabolites are associated with type 2 diabetes risk in the Prevención con Dieta Mediterránea (PREDIMED) trial
Papandreou C, Bulló M, Zheng Y, Ruiz-Canela M, Yu E, Guasch-Ferré M, Toledo E, Clish C, Corella D, Estruch R, Ros E, Fitó M, Arós F, Fiol M, Lapetra J, Serra-Majem L, Gómez-Gracia E, Liang L, Fragkiadakis GA, Razquin C, Hu FB, Salas-Salvadó J |
The American journal of clinical nutrition | 2018 |
|
Metabolomics and Metabolic Diseases: Where Do We Stand?
CB Newgard |
Cell Metabolism | 2017 |
|
The ins and outs of endoplasmic reticulum‐controlled lipid biosynthesis
J Jacquemyn, A Cascalho, RE Goodchild |
EMBO reports | 2017 |
|
Activation of IRF1 in Human Adipocytes Leads to Phenotypes Associated with Metabolic Disease
M Friesen, R Camahort, YK Lee, F Xia, RE Gerszten, EP Rhee, RC Deo, CA Cowan |
Stem Cell Reports | 2017 |
|
Absence of Carbohydrate Response Element Binding Protein in Adipocytes Causes Systemic Insulin Resistance and Impairs Glucose Transport
A Vijayakumar, P Aryal, J Wen, I Syed, RP Vazirani, PM Moraes-Vieira, JP Camporez, MR Gallop, RJ Perry, OD Peroni, GI Shulman, A Saghatelian, TE McGraw, BB Kahn |
Cell Reports | 2017 |
|
Comparing identified and statistically significant lipids and polar metabolites in 15-year old serum and dried blood spot samples for longitudinal studies: Comparing lipids and metabolites in serum and DBS samples
JE Kyle, CP Casey, KG Stratton, EM Zink, YM Kim, X Zheng, ME Monroe, KK Weitz, KJ Bloodsworth, DJ Orton, YM Ibrahim, RJ Moore, CG Lee, C Pedersen, E Orwoll, RD Smith, KE Burnum-Johnson, ES Baker |
Rapid communications in mass spectrometry : RCM | 2017 |
|
Metabolomic profiling identifies potential pathways involved in the interaction of iron homeostasis with glucose metabolism
L Stechemesser, SK Eder, A Wagner, W Patsch, A Feldman, M Strasser, S Auer, D Niederseer, U Huber-Schönauer, B Paulweber, S Zandanell, S Ruhaltinger, D Weghuber, E Haschke-Becher, C Grabmer, E Rohde, C Datz, TK Felder, E Aigner |
Molecular Metabolism | 2017 |
|
Metabolites Associated With Lean Mass and Adiposity in Older Black Men
RA Murphy, SC Moore, M Playdon, O Meirelles, AB Newman, I Milijkovic, SB Kritchevsky, A Schwartz, BH Goodpaster, J Sampson, P Cawthon, EM Simonsick, RE Gerszten, CB Clish, TB Harris |
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences | 2017 |
|
HELZ2 Is an IFN Effector Mediating Suppression of Dengue Virus
DN Fusco, H Pratt, S Kandilas, SS Cheon, W Lin, DA Cronkite, M Basavappa, KL Jeffrey, A Anselmo, R Sadreyev, C Yapp, X Shi, JF O'Sullivan, RE Gerszten, T Tomaru, S Yoshino, T Satoh, RT Chung |
Frontiers in microbiology | 2017 |
|
Form(ul)ation of adipocytes by lipids
K Lapid, JM Graff |
Adipocyte | 2017 |
|
Insulin induces a shift in lipid and primary carbon metabolites in a model of fasting-induced insulin resistance
KI Olmstead, MR la Frano, J Fahrmann, D Grapov, JA Viscarra, JW Newman, O Fiehn, DE Crocker, FV Filipp, RM Ortiz |
Metabolomics | 2017 |
|
Association of amine biomarkers with incident dementia and Alzheimer's disease in the Framingham Study
V Chouraki, SR Preis, Q Yang, A Beiser, S Li, MG Larson, G Weinstein, TJ Wang, RE Gerszten, RS Vasan, S Seshadri |
Alzheimer's and Dementia | 2017 |
|
A methodology for elucidating regulatory mechanisms leading to changes in lipid profiles
FC Pinto, S Ravipati, DA Barrett, TC Hodgman |
Metabolomics | 2017 |
|
Metabolic profiling of polycystic ovary syndrome reveals interactions with abdominal obesity
AC Alves, B Valcarcel, VP Mäkinen, L Morin-Papunen, S Sebert, AJ Kangas, P Soininen, S Das, MD Iorio, L Coin, M Ala-Korpela, MR Järvelin, S Franks |
International Journal of Obesity | 2017 |
|
Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms
V Rusu, E Hoch, JM Mercader, DE Tenen, M Gymrek, CR Hartigan, M DeRan, M Grotthuss, P Fontanillas, A Spooner, G Guzman, AA Deik, KA Pierce, C Dennis, CB Clish, SA Carr, BK Wagner, M Schenone, MC Ng, BH Chen, F Centeno-Cruz, C Zerrweck, L Orozco, DM Altshuler, SL Schreiber, JC Florez, SB Jacobs, ES Lander, MC Ng, D Shriner, BH Chen, J Li, WM Chen, X Guo, J Liu, SJ Bielinski, LR Yanek, MA Nalls, ME Comeau, LJ Rasmussen-Torvik, RA Jensen, DS Evans, YV Sun, P An, SR Patel, Y Lu, J Long, LL Armstrong, L Wagenknecht, L Yang, BM Snively, ND Palmer, P Mudgal, CD Langefeld, KL Keene, BI Freedman, JC Mychaleckyj, U Nayak, LJ Raffel, MO Goodarzi, YD Chen, HA Taylor, A Correa, M Sims, D Couper, JS Pankow, E Boerwinkle, A Adeyemo, A Doumatey, G Chen, RA Mathias, D Vaidya, AB Singleton, AB Zonderman, RP Igo, JR Sedor, EK Kabagambe, DS Siscovick, B McKnight, K Rice, Y Liu, WC Hsueh, W Zhao, LF Bielak, A Kraja, MA Province, EP Bottinger, O Gottesman, Q Cai, W Zheng, WJ Blot, WL Lowe, JA Pacheco, DC Crawford, E Grundberg, SS Rich, MG Hayes, XO Shu, RJ Loos, IB Borecki, PA Peyser, SR Cummings, BM Psaty, M Fornage, SK Iyengar, MK Evans, DM Becker, WH Kao, JG Wilson, JI Rotter, MM Sale, S Liu, CN Rotimi, DW Bowden, JM Mercader, A Huerta-Chagoya, H García-Ortiz, H Moreno-Macías, A Manning, L Caulkins, NP Burtt, J Flannick, N Patterson, CA Aguilar-Salinas, T Tusié-Luna, D Altshuler, JC Florez, A Martínez-Hernández, F Centeno-Cruz, FM Barajas-Olmos, C Zerrweck, C Contreras-Cubas, E Mendoza-Caamal, C Revilla-Monsalve, S Islas-Andrade, E Córdova, X Soberón, L Orozco, C González-Villalpando, ME González-Villalpando, CA Haiman, L Wilkens, LL Marchand, K Monroe, L Kolonel, O Arellano-Campos, ML Ordóñez-Sánchez, M Rodríguez-Torres, Y Segura-Kato, R Rodríguez-Guillén, I Cruz-Bautista, LL Muñoz-Hernandez, T Sáenz, D Gómez, U Alvirde, P Almeda-Valdés, ML Cortes |
Cell | 2017 |
|
Metabolic profiles of exercise in patients with McArdle disease or mitochondrial myopathy
NF Delaney, R Sharma, L Tadvalkar, CB Clish, RG Haller, VK Mootha |
Proceedings of the National Academy of Sciences | 2017 |
|
Serum Monounsaturated Triacylglycerol Predicts Steatohepatitis in Patients with Non-alcoholic Fatty Liver Disease and Chronic Hepatitis B
R Yang, C Hu, W Sun, Q Pan, F Shen, Z Yang, Q Su, G Xu, J Fan |
Scientific Reports | 2017 |
|
Early gestational maternal low-protein diet diminishes hepatic response to fasting in young adult male mice
N Sato, K Sudo, M Mori, C Imai, M Muramatsu, M Sugimoto |
Scientific Reports | 2017 |
|
Metabolomics of Diabetic Retinopathy
G Liew, Z Lei, G Tan, N Joachim, IV Ho, TY Wong, P Mitchell, B Gopinath, B Crossett |
Current Diabetes Reports | 2017 |
|
A combination of plasma phospholipid fatty acids and its association with incidence of type 2 diabetes: The EPIC-InterAct case-cohort study
F Imamura, SJ Sharp, A Koulman, MB Schulze, J Kröger, JL Griffin, JM Huerta, M Guevara, I Sluijs, A Agudo, E Ardanaz, B Balkau, H Boeing, V Chajes, CC Dahm, C Dow, G Fagherazzi, EJ Feskens, PW Franks, D Gavrila, M Gunter, R Kaaks, TJ Key, KT Khaw, T Kühn, O Melander, E Molina-Portillo, PM Nilsson, A Olsen, K Overvad, D Palli, S Panico, O Rolandsson, S Sieri, C Sacerdote, N Slimani, AM Spijkerman, A Tjønneland, R Tumino, YT van der Schouw, C Langenberg, E Riboli, NG Forouhi, NJ Wareham, RC Ma |
PLoS Medicine | 2017 |
|
Multi-parameter comparison of a standardized mixed meal tolerance test in healthy and type 2 diabetic subjects: the PhenFlex challenge
S Wopereis, JH Stroeve, A Stafleu, GC Bakker, J Burggraaf, MJ van Erk, L Pellis, R Boessen, AA Kardinaal, B Ommen |
Genes & Nutrition | 2017 |
|
Plasma lipidomic profiles and cardiovascular events in a randomized intervention trial with the Mediterranean diet
Estefanía Toledo, Dong D Wang, Miguel Ruiz-Canela, Clary B Clish, Cristina Razquin, Yan Zheng, Marta Guasch-Ferré, Adela Hruby, Dolores Corella, Enrique Gómez-Gracia, Miquel Fiol, Ramón Estruch, Emilio Ros, José Lapetra, Montserrat Fito, Fernando Aros, Luis Serra-Majem, Liming Liang, Jordi Salas-Salvadó, Frank B Hu, Miguel A Martínez-González |
The American journal of clinical nutrition | 2017 |
|
Plasma Ceramides, Mediterranean Diet, and Incident Cardiovascular Disease in the PREDIMED Trial (Prevención con Dieta Mediterránea)Clinical Perspective
DD Wang, E Toledo, A Hruby, BA Rosner, WC Willett, Q Sun, C Razquin, Y Zheng, M Ruiz-Canela, M Guasch-Ferré, D Corella, E Gómez-Gracia, M Fiol, R Estruch, E Ros, J Lapetra, M Fito, F Aros, L Serra-Majem, CH Lee, CB Clish, L Liang, J Salas-Salvadó, MA Martínez-González, FB Hu |
Circulation | 2017 |
|
Metabolomic profiles as reliable biomarkers of dietary composition
T Esko, JN Hirschhorn, HA Feldman, YH Hsu, AA Deik, CB Clish, CB Ebbeling, DS Ludwig |
The American journal of clinical nutrition | 2017 |
|
A Decade of Genetic and Metabolomic Contributions to Type 2 Diabetes Risk Prediction
J Merino, MS Udler, A Leong, JB Meigs |
Current Diabetes Reports | 2017 |
|
Effect of carnosine supplementation on the plasma lipidome in overweight and obese adults: a pilot randomised controlled trial
E Baye, J Ukropec, MP de Courten, S Vallova, P Krumpolec, T Kurdiova, G Aldini, B Ukropcova, B Courten |
Scientific Reports | 2017 |
|
Impaired β -Oxidation and Altered Complex Lipid Fatty Acid Partitioning with Advancing CKD
F Afshinnia, TM Rajendiran, T Soni, J Byun, S Wernisch, KM Sas, J Hawkins, K Bellovich, D Gipson, G Michailidis, S Pennathur |
Journal of the American Society of Nephrology : JASN | 2017 |
|
Shared and distinct lipid-lipid interactions in plasma and affected tissues in a diabetic mouse model
KM Sas, J Lin, TM Rajendiran, T Soni, V Nair, LM Hinder, HV Jagadish, TW Gardner, SF Abcouwer, FC Brosius, EL Feldman, M Kretzler, G Michailidis, S Pennathur |
Journal of lipid research | 2017 |
|
Metabolites Associated With Risk of Developing Mobility Disability in the Health, Aging and Body Composition Study
RA Murphy, S Moore, M Playdon, S Kritchevsky, AB Newman, S Satterfield, H Ayonayon, C Clish, R Gerszten, TB Harris |
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences | 2017 |
|
Lipidomic risk score independently and cost-effectively predicts risk of future type 2 diabetes: results from diverse cohorts
M Mamtani, H Kulkarni, G Wong, JM Weir, CK Barlow, TD Dyer, L Almasy, MC Mahaney, AG Comuzzie, DC Glahn, DJ Magliano, P Zimmet, J Shaw, S Williams-Blangero, R Duggirala, J Blangero, PJ Meikle, JE Curran |
Lipids in Health and Disease | 2016 |
|
Gender, Contraceptives and Individual Metabolic Predisposition Shape a Healthy Plasma Lipidome
S Sales, J Graessler, S Ciucci, R Al-Atrib, T Vihervaara, K Schuhmann, D Kauhanen, M Sysi-Aho, SR Bornstein, M Bickle, CV Cannistraci, K Ekroos, A Shevchenko |
Scientific Reports | 2016 |
|
Circulating MicroRNA-122 Is Associated With the Risk of New-Onset Metabolic Syndrome and Type 2 Diabetes
P Willeit, P Skroblin, AR Moschen, X Yin, D Kaudewitz, A Zampetaki, T Barwari, M Whitehead, CM Ramírez, L Goedeke, N Rotllan, E Bonora, AD Hughes, P Santer, C Fernández-Hernando, H Tilg, J Willeit, S Kiechl, M Mayr |
Diabetes | 2016 |
|
The suppression of hepatic glucose production improves metabolism and insulin sensitivity in subcutaneous adipose tissue in mice
S Casteras, A Abdul-Wahed, M Soty, F Vulin, H Guillou, M Campana, HL Stunff, L Pirola, F Rajas, G Mithieux, A Gautier-Stein |
Diabetologia | 2016 |
|
Metabolite Profiles of Diabetes Incidence and Intervention Response in the Diabetes Prevention Program
GA Walford, Y Ma, C Clish, JC Florez, TJ Wang, RE Gerszten |
Diabetes | 2016 |
|
Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis
LA Lotta, RA Scott, SJ Sharp, S Burgess, J Luan, T Tillin, AF Schmidt, F Imamura, ID Stewart, JR Perry, L Marney, A Koulman, ED Karoly, NG Forouhi, RJ Sjögren, E Näslund, JR Zierath, A Krook, DB Savage, JL Griffin, N Chaturvedi, AD Hingorani, KT Khaw, I Barroso, MI McCarthy, S ORahilly, NJ Wareham, C Langenberg, C Minelli |
PLoS Medicine | 2016 |
|
Skeletal muscle and plasma lipidomic signatures of insulin resistance and overweight/obesity in humans: Lipidomics in Insulin Resistance and Obesity
KT Tonks, AC Coster, MJ Christopher, R Chaudhuri, A Xu, J Gagnon-Bartsch, DJ Chisholm, DE James, PJ Meikle, JR Greenfield, D Samocha-Bonet |
Obesity | 2016 |
|
Lipidomics—Reshaping the Analysis and Perception of Type 2 Diabetes
D Markgraf, H Al-Hasani, S Lehr |
International journal of molecular sciences | 2016 |
|
What Have Metabolomics Approaches Taught Us About Type 2 Diabetes?
A Gonzalez-Franquesa, AM Burkart, E Isganaitis, ME Patti |
Current Diabetes Reports | 2016 |
|
Metabolomic Profiles of Body Mass Index in the Framingham Heart Study Reveal Distinct Cardiometabolic Phenotypes
JE Ho, MG Larson, A Ghorbani, S Cheng, MH Chen, M Keyes, EP Rhee, CB Clish, RS Vasan, RE Gerszten, TJ Wang, D Meyre |
PloS one | 2016 |
|
An exome array study of the plasma metabolome
EP Rhee, Q Yang, B Yu, X Liu, S Cheng, A Deik, KA Pierce, K Bullock, JE Ho, D Levy, JC Florez, S Kathiresan, MG Larson, RS Vasan, CB Clish, TJ Wang, E Boerwinkle, CJ ODonnell, RE Gerszten |
Nature Communications | 2016 |
|
Metabolomic Profiling in Relation to New-Onset Atrial Fibrillation (from the Framingham Heart Study)
D Ko, EM Riles, EG Marcos, JW Magnani, SA Lubitz, H Lin, MT Long, RB Schnabel, DD McManus, PT Ellinor, VS Ramachandran, TJ Wang, RE Gerszten, EJ Benjamin, X Yin, M Rienstra |
The American Journal of Cardiology | 2016 |
|
Metabolomics in Prediabetes and Diabetes: A Systematic Review and Meta-analysis
M Guasch-Ferré, A Hruby, E Toledo, CB Clish, MA Martínez-González, J Salas-Salvadó, FB Hu |
Diabetes care | 2016 |
|
Human gut microbes impact host serum metabolome and insulin sensitivity
HK Pedersen, V Gudmundsdottir, HB Nielsen, T Hyotylainen, T Nielsen, BA Jensen, K Forslund, F Hildebrand, E Prifti, G Falony, EL Chatelier, F Levenez, J Doré, I Mattila, DR Plichta, P Pöhö, LI Hellgren, M Arumugam, S Sunagawa, S Vieira-Silva, T Jørgensen, JB Holm, K Trošt, MH Consortium, K Kristiansen, S Brix, J Raes, J Wang, T Hansen, P Bork, S Brunak, M Oresic, SD Ehrlich, O Pedersen |
Nature | 2016 |
|
Metabolite Profiles Predict Acute Kidney Injury and Mortality in Patients Undergoing Transcatheter Aortic Valve Replacement
S Elmariah, LA Farrell, M Daher, X Shi, MJ Keyes, CH Cain, E Pomerantsev, GJ Vlahakes, I Inglessis, JJ Passeri, IF Palacios, CS Fox, EP Rhee, RE Gerszten |
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease | 2016 |
|
Intervention Trials with the Mediterranean Diet in Cardiovascular Prevention: Understanding Potential Mechanisms through Metabolomic Profiling
MA Martinez-Gonzalez, M Ruiz-Canela, A Hruby, L Liang, A Trichopoulou, FB Hu |
The Journal of nutrition | 2016 |
|
Serum metabolite profile associates with the development of metabolic co-morbidities in first-episode psychosis
T Suvitaival, O Mantere, T Kieseppä, I Mattila, P Pöhö, T Hyötyläinen, J Suvisaari, M Orešič |
Translational Psychiatry | 2016 |
|
Detection of Independent Associations of Plasma Lipidomic Parameters with Insulin Sensitivity Indices Using Data Mining Methodology
S Kopprasch, S Dheban, K Schuhmann, A Xu, KM Schulte, CJ Simeonovic, PE Schwarz, SR Bornstein, A Shevchenko, J Graessler, V Sánchez-Margalet |
PloS one | 2016 |
|
An Unbiased Lipidomics Approach Identifies Early Second Trimester Lipids Predictive of Maternal Glycemic Traits and Gestational Diabetes Mellitus
L Lu, A Koulman, CJ Petry, B Jenkins, L Matthews, IA Hughes, CL Acerini, KK Ong, DB Dunger |
Diabetes care | 2016 |
|
Lipidomic Signature of Progression of Chronic Kidney Disease in the Chronic Renal Insufficiency Cohort
F Afshinnia, TM Rajendiran, A Karnovsky, T Soni, X Wang, D Xie, W Yang, T Shafi, MR Weir, J He, CS Brecklin, EP Rhee, JR Schelling, A Ojo, H Feldman, G Michailidis, S Pennathur, LJ Appel, AS Go, JW Kusek, JP Lash, RR Townsend |
Kidney International Reports | 2016 |
|
Identification of Shared and Unique Serum Lipid Profiles in Diabetes Mellitus and Myocardial Infarction
S Kjellqvist, C Klose, MA Surma, G Hindy, IG Mollet, A Johansson, P Chavaux, J Gottfries, K Simons, O Melander, C Fernandez |
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease | 2016 |
|
Nutrigenomics, the Microbiome, and Gene-Environment Interactions: New Directions in Cardiovascular Disease Research, Prevention, and Treatment: A Scientific Statement From the American Heart Association
JF Ferguson, H Allayee, RE Gerszten, F Ideraabdullah, PM Kris-Etherton, JM Ordovás, EB Rimm, TJ Wang, BJ Bennett |
Circulation. Cardiovascular genetics | 2016 |
|
Metabolomics: an emerging but powerful tool for precision medicine
CB Clish |
Molecular Case Studies | 2015 |
|
The Subtle Balance between Lipolysis and Lipogenesis: A Critical Point in Metabolic Homeostasis
C Saponaro, M Gaggini, F Carli, A Gastaldelli |
Nutrients | 2015 |
|
Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis
J Miao, AV Ling, PV Manthena, ME Gearing, MJ Graham, RM Crooke, KJ Croce, RM Esquejo, CB Clish, E Torrecilla, GF Vázquez, MA Rubio, L Cabrerizo, A Barabash, AS Pernaute, AJ Torres, D Vicent, SB Biddinger |
Nature Communications | 2015 |
|
Mechanistic insights revealed by lipid profiling in monogenic insulin resistance syndromes
M Eiden, A Koulman, M Hatunic, JA West, S Murfitt, M Osei, C Adams, X Wang, Y Chu, L Marney, LD Roberts, S O’Rahilly, RK Semple, DB Savage, JL Griffin |
Genome Medicine | 2015 |
|
Phenotypic flexibility as a measure of health: the optimal nutritional stress response test
JH Stroeve, H Wietmarschen, BH Kremer, B Ommen, S Wopereis |
Genes & Nutrition | 2015 |
|
HdhQ111 Mice Exhibit Tissue Specific Metabolite Profiles that Include Striatal Lipid Accumulation
JB Carroll, A Deik, E Fossale, RM Weston, JR Guide, J Arjomand, S Kwak, CB Clish, ME MacDonald, S Humbert |
PloS one | 2015 |
|
Metabolomics of renal venous plasma from individuals with unilateral renal artery stenosis and essential hypertension:
EP Rhee, CB Clish, KA Pierce, A Saad, LO Lerman, SC Textor |
Journal of Hypertension | 2015 |
|
Poorly controlled type 2 diabetes is accompanied by significant morphological and ultrastructural changes in both erythrocytes and in thrombin-generated fibrin: implications for diagnostics
E Pretorius, J Bester, N Vermeulen, S Alummoottil, P Soma, AV Buys, DB Kell |
Cardiovascular Diabetology | 2015 |
|
Identification of putative biomarkers for prediabetes by metabolome analysis of rat models of type 2 diabetes
N Yokoi, M Beppu, E Yoshida, R Hoshikawa, S Hidaka, T Matsubara, M Shinohara, Y Irino, N Hatano, S Seino |
Metabolomics | 2015 |
|
Metabolomics and Diabetes: Analytical and Computational Approaches
KM Sas, A Karnovsky, G Michailidis, S Pennathur |
Diabetes | 2015 |
|
Metabolite Profiling and Cardiovascular Event Risk: A Prospective Study of 3 Population-Based Cohorts
P Wurtz, AS Havulinna, P Soininen, T Tynkkynen, D Prieto-Merino, T Tillin, A Ghorbani, A Artati, Q Wang, M Tiainen, AJ Kangas, J Kettunen, J Kaikkonen, V Mikkila, A Jula, M Kahonen, T Lehtimaki, DA Lawlor, TR Gaunt, AD Hughes, N Sattar, T Illig, J Adamski, TJ Wang, M Perola, S Ripatti, RS Vasan, OT Raitakari, RE Gerszten, JP Casas, N Chaturvedi, M Ala-Korpela, V Salomaa |
Circulation | 2015 |
|
Distinct metabolomic signatures are associated with longevity in humans
S Cheng, MG Larson, EL McCabe, JM Murabito, EP Rhee, JE Ho, PF Jacques, A Ghorbani, M Magnusson, AL Souza, AA Deik, KA Pierce, K Bullock, CJ O’Donnell, O Melander, CB Clish, RS Vasan, RE Gerszten, TJ Wang |
Nature Communications | 2015 |
|
The prediction of type 2 diabetes in women with previous gestational diabetes mellitus using lipidomics
M Lappas, PA Mundra, G Wong, K Huynh, D Jinks, HM Georgiou, M Permezel, PJ Meikle |
Diabetologia | 2015 |
|
Association between insulin resistance and plasma amino acid profile in non-diabetic Japanese subjects
C Yamada, M Kondo, N Kishimoto, T Shibata, Y Nagai, T Imanishi, T Oroguchi, N Ishii, Y Nishizaki |
Journal of Diabetes Investigation | 2015 |
|
CMPF Does Not Associate with Impaired Glucose Metabolism in Individuals with Features of Metabolic Syndrome
MA Lankinen, K Hanhineva, M Kolehmainen, M Lehtonen, S Auriola, H Mykkänen, K Poutanen, U Schwab, M Uusitupa, AG Passi |
PloS one | 2015 |
|
Roux-en-Y Gastric Bypass Surgery Induces Early Plasma Metabolomic and Lipidomic Alterations in Humans Associated with Diabetes Remission
T Arora, V Velagapudi, DJ Pournaras, R Welbourn, CW le Roux, M Orešič, F Bäckhed, M Covasa |
PloS one | 2015 |
|
Defining the Metabolome: Size, Flux, and Regulation
N Zamboni, A Saghatelian, GJ Patti |
Molecular Cell | 2015 |
|
Edible Bird’s Nest Prevents High Fat Diet-Induced Insulin Resistance in Rats
Z Yida, MU Imam, M Ismail, DJ Ooi, N Sarega, NH Azmi, N Ismail, KW Chan, Z Hou, NB Yusuf |
Journal of Diabetes Research | 2015 |
|
Modulation of the lipidomic profile due to a lipid challenge and fitness level: a postprandial study
C Morris, CM O’Grada, MF Ryan, MJ Gibney, HM Roche, ER Gibney, L Brennan |
Lipids in Health and Disease | 2015 |
|
A Metabolomic Approach to Understanding the Metabolic Link between Obesity and Diabetes
S Park, KC Sadanala, EK Kim |
Molecules and Cells | 2015 |
|
Metabolomics Reveals Metabolically Healthy and Unhealthy Obese Individuals Differ in their Response to a Caloric Challenge
F Badoud, KP Lam, M Perreault, MA Zulyniak, P Britz-McKibbin, DM Mutch, HM Roche |
PloS one | 2015 |
|
Hyphenating size-exclusion chromatography with electrospray mass spectrometry; using on-line liquid-liquid extraction to study the lipid composition of lipoprotein particles: Lipoprotein analysis
M Osei, JL Griffin, A Koulman |
Rapid communications in mass spectrometry : RCM | 2015 |
|
Lipidomics to Assess Omega 3 Bioactivity
F Visioli |
Journal of Clinical Medicine | 2015 |
|
Platelet Lipidomics: Modern Day Perspective on Lipid Discovery and Characterization in Platelets
VB ODonnell, RC Murphy, SP Watson |
Circulation research | 2014 |
|
Evaluation of dietary effects on hepatic lipids in high fat and placebo diet fed rats by in vivo MRS and LC-MS techniques
J Yaligar, V Gopalan, OW Kiat, S Sugii, G Shui, BD Lam, CJ Henry, MR Wenk, ES Tai, SS Velan |
PloS one | 2014 |
|
Role of Nutrient-Sensing Signals in the Pathogenesis of Diabetic Nephropathy
S Kume, D Koya, T Uzu, H Maegawa |
BioMed Research International | 2014 |
|
Discovery of a Class of Endogenous Mammalian Lipids with Anti-Diabetic and Anti-inflammatory Effects
MM Yore, I Syed, PM Moraes-Vieira, T Zhang, MA Herman, EA Homan, RT Patel, J Lee, S Chen, OD Peroni, AS Dhaneshwar, A Hammarstedt, U Smith, TE McGraw, A Saghatelian, BB Kahn |
Cell | 2014 |
|
The development and validation of a fast and robust dried blood spot based lipid profiling method to study infant metabolism
A Koulman, P Prentice, MC Wong, L Matthews, NJ Bond, M Eiden, JL Griffin, DB Dunger |
Metabolomics | 2014 |
|
Increased amino acids levels and the risk of developing of hypertriglyceridemia in a 7-year follow-up
DO Mook-Kanamori, W Römisch-Margl, G Kastenmüller, C Prehn, AK Petersen, T Illig, C Gieger, R Wang-Sattler, C Meisinger, A Peters, J Adamski, K Suhre |
Journal of Endocrinological Investigation | 2014 |
|
Introduction to personalized medicine in diabetes mellitus
HS Glauber, N Rishe, E Karnieli |
Rambam Maimonides Medical Journal | 2014 |
|
Comprehensive analysis of lipids in biological systems by liquid chromatography-mass spectrometry
T Cajka, O Fiehn |
TrAC Trends in Analytical Chemistry | 2014 |
|
Metabolite Traits and Genetic Risk Provide Complementary Information for the Prediction of Future Type 2 Diabetes
GA Walford, BC Porneala, M Dauriz, JL Vassy, S Cheng, EP Rhee, TJ Wang, JB Meigs, RE Gerszten, JC Florez |
Diabetes care | 2014 |
|
Placing epidemiological results in the context of multiplicity and typical correlations of exposures
CJ Patel, JP Ioannidis |
Journal of epidemiology and community health | 2014 |
|
Estrogen signaling prevents diet-induced hepatic insulin resistance in male mice with obesity
L Zhu, MN Martinez, CH Emfinger, BT Palmisano, JM Stafford |
American journal of physiology. Endocrinology and metabolism | 2014 |
|
A systematic survey of lipids across mouse tissues
M Jain, S Ngoy, SA Sheth, RA Swanson, EP Rhee, R Liao, CB Clish, VK Mootha, R Nilsson |
American journal of physiology. Endocrinology and metabolism | 2014 |
|
Applying metabolomics to uncover novel biology in ARDS
AJ Rogers, MA Matthay |
American journal of physiology. Lung cellular and molecular physiology | 2014 |
|
Mass Spectrometry-based Lipidomics and Its Application toBiomedical Research
Z Wu, JC Shon, KH Liu |
Journal of Lifestyle Medicine | 2014 |
|
Metabolomic Derangements Are Associated with Mortality in Critically Ill Adult Patients
AJ Rogers, M McGeachie, RM Baron, L Gazourian, JA Haspel, K Nakahira, LE Fredenburgh, GM Hunninghake, BA Raby, MA Matthay, RM Otero, VG Fowler, EP Rivers, CW Woods, S Kingsmore, RJ Langley, AM Choi, SM Parikh |
PloS one | 2014 |
|
Serum profiling of healthy aging identifies phospho- and sphingolipid species as markers of human longevity
Montoliu I, Scherer M, Beguelin F, DaSilva L, Mari D, Salvioli S, Martin FP, Capri M, Bucci L, Ostan R, Garagnani P, Monti D, Biagi E, Brigidi P, Kussmann M, Rezzi S, Franceschi C, Collino S |
Aging | 2014 |
|
2-aminoadipic acid is a novel biomarker of diabetes risk and modulates glucose homeostasis
Thomas Wang, Debby Ngo, Nikolaos Psychogios, Andre Dejam, Martin Larson, Ramachandran Vasan, Anahita Ghorbani, John O'Sullivan, Susan Cheng, Eugene Rhee, Sumita Sinha, Elizabeth McCabe, Caroline Fox, Christopher O'Donnell, Jennifer Ho, Jose Florez, Martin Magnusson, Kerry Pierce, Amanda Souza, Yi Yu, Christian Carter, Peter Light, Olle Melander, Clary Clish, Robert E. Gerszten |
Journal of Clinical Investigation | 2013 |
|
Prediction of non-alcoholic fatty-liver disease and liver fat content by serum molecular lipids
M Orešič, T Hyötyläinen, A Kotronen, P Gopalacharyulu, H Nygren, J Arola, S Castillo, I Mattila, A Hakkarainen, RJ Borra, MJ Honka, A Verrijken, S Francque, P Iozzo, M Leivonen, N Jaser, A Juuti, TI Sørensen, P Nuutila, L Gaal, H Yki-Järvinen |
Diabetologia | 2013 |
|
Plasma sphingosine-1-phosphate is elevated in obesity
GM Kowalski, AL Carey, A Selathurai, BA Kingwell, CR Bruce |
PloS one | 2013 |
|
Molecular network analysis of phosphotyrosine and lipid metabolism in hepatic PTP1b deletion mice
ER Miraldi, H Sharfi, RH Friedline, H Johnson, T Zhang, KS Lau, HJ Ko, TG Curran, KM Haigis, MB Yaffe, R Bonneau, DA Lauffenburger, BB Kahn, JK Kim, BG Neel, A Saghatelian, FM White |
Integrative Biology | 2013 |
|
Role of fat body lipogenesis in protection against the effects of caloric overload in Drosophila
LP Musselman, JL Fink, PV Ramachandran, BW Patterson, AL Okunade, E Maier, MR Brent, J Turk, TJ Baranski |
The Journal of biological chemistry | 2013 |
|
Relationship between postprandial metabolomics and colon motility in children with constipation
L Rodriguez, LD Roberts, J LaRosa, N Heinz, R Gerszten, S Nurko, AM Goldstein |
Neurogastroenterology & Motility | 2013 |
|
Biomarkers for Type 2 Diabetes and Impaired Fasting Glucose Using a Nontargeted Metabolomics Approach
C Menni, E Fauman, I Erte, JR Perry, G Kastenmuller, SY Shin, AK Petersen, C Hyde, M Psatha, KJ Ward, W Yuan, M Milburn, CN Palmer, TM Frayling, J Trimmer, JT Bell, C Gieger, RP Mohney, MJ Brosnan, K Suhre, N Soranzo, TD Spector |
Diabetes | 2013 |
|
A Genome-wide Association Study of the Human Metabolome in a Community-Based Cohort
EP Rhee, JE Ho, MH Chen, D Shen, S Cheng, MG Larson, A Ghorbani, X Shi, IT Helenius, CJ O’Donnell, AL Souza, A Deik, KA Pierce, K Bullock, GA Walford, RS Vasan, JC Florez, C Clish, JR Yeh, TJ Wang, RE Gerszten |
Cell Metabolism | 2013 |
|
Fatty acids differentially regulate insulin resistance through endoplasm reticulum stress-mediated induction of tribbles homologue 3: a potential link between dietary fat composition and the pathophysiological outcomes of obesity
T Geng, W Hu, MH Broadwater, JM Snider, J Bielawski, SB Russo, JH Schwacke, J Ross, LA Cowart |
Diabetologia | 2013 |
|
Systems Epidemiology: A New Direction in Nutrition and Metabolic Disease Research
MC Cornelis, FB Hu |
Current Nutrition Reports | 2013 |
|
Biomolecular Signatures of Diabetic Wound Healing by Structural Mass Spectrometry
KM Hines, S Ashfaq, JM Davidson, SR Opalenik, JP Wikswo, JA McLean |
Analytical Chemistry | 2013 |
|
Topographical body fat distribution links to amino acid and lipid metabolism in healthy non-obese women
FP Martin, I Montoliu, S Collino, M Scherer, P Guy, I Tavazzi, A Thorimbert, S Moco, MP Rothney, DL Ergun, M Beaumont, F Ginty, SD Qanadli, L Favre, V Giusti, S Rezzi |
PloS one | 2013 |
|
The potential of novel biomarkers to improve risk prediction of type 2 diabetes
C Herder, B Kowall, AG Tabak, W Rathmann |
Diabetologia | 2013 |
|
Inclusion of plasma lipid species improves classification of individuals at risk of type 2 diabetes
G Wong, CK Barlow, JM Weir, JB Jowett, DJ Magliano, P Zimmet, J Shaw, PJ Meikle |
PloS one | 2013 |
|
Plasma lipid composition and risk of developing cardiovascular disease
C Fernandez, M Sandin, JL Sampaio, P Almgren, K Narkiewicz, M Hoffmann, T Hedner, B Wahlstrand, K Simons, A Shevchenko, P James, O Melander |
PloS one | 2013 |
|
Biochemical and high throughput microscopic assessment of fat mass in Caenorhabditis elegans
EC Pino, CM Webster, CE Carr, AA Soukas |
Journal of visualized experiments : JoVE | 2013 |
|
Myristate-derived d16:0 sphingolipids constitute a cardiac sphingolipid pool with distinct synthetic routes and functional properties
SB Russo, R Tidhar, AH Futerman, LA Cowart |
The Journal of biological chemistry | 2013 |
|
Clinical metabolomics paves the way towards future healthcare strategies
S Collino, FP Martin, S Rezzi |
British Journal of Clinical Pharmacology | 2013 |
|
A combined epidemiologic and metabolomic approach improves CKD prediction
EP Rhee, CB Clish, A Ghorbani, MG Larson, S Elmariah, E McCabe, Q Yang, S Cheng, K Pierce, A Deik, AL Souza, L Farrell, C Domos, RW Yeh, I Palacios, K Rosenfield, RS Vasan, JC Florez, TJ Wang, CS Fox, RE Gerszten |
Journal of the American Society of Nephrology : JASN | 2013 |
|
Metabolite profiles during oral glucose challenge
JE Ho, MG Larson, RS Vasan, A Ghorbani, S Cheng, EP Rhee, JC Florez, CB Clish, RE Gerszten, TJ Wang |
Diabetes | 2013 |
|
Lipidomics of familial longevity
V Gonzalez-Covarrubias, M Beekman, HW Uh, A Dane, J Troost, I Paliukhovich, FM Kloet, J Houwing-Duistermaat, RJ Vreeken, T Hankemeier, EP Slagboom |
Aging Cell | 2013 |
|
Metabolomics Reveals Broad-Scale Metabolic Perturbations in Hyperglycemic Mothers During Pregnancy
DM Scholtens, MJ Muehlbauer, NR Daya, RD Stevens, AR Dyer, LP Lowe, BE Metzger, CB Newgard, JR Bain, WL Lowe |
Diabetes care | 2013 |
|
"Prediction Is Very Hard, Especially About the Future": New Biomarkers for Type 2 Diabetes?
WL Lowe, JR Bain |
Diabetes | 2013 |
|
Serum TAG Analysis Differentiates Between Genetic and Obesity-Associated NAFLD
DG Mashek, AS Greenberg |
Diabetes | 2013 |
|
Reproducibility of Metabolomic Profiles among Men and Women in 2 Large Cohort Studies
MK Townsend, CB Clish, P Kraft, C Wu, AL Souza, AA Deik, SS Tworoger, BM Wolpin |
Clinical chemistry | 2013 |
|
Plasma lipid profiling in a large population-based cohort
JM Weir, G Wong, CK Barlow, MA Greeve, A Kowalczyk, L Almasy, AG Comuzzie, MC Mahaney, JB Jowett, J Shaw, JE Curran, J Blangero, PJ Meikle |
Journal of lipid research | 2013 |
|
A Plasma Long‐Chain Acylcarnitine Predicts Cardiovascular Mortality in Incident Dialysis Patients
S Kalim, CB Clish, J Wenger, S Elmariah, RW Yeh, JJ Deferio, K Pierce, A Deik, RE Gerszten, R Thadhani, EP Rhee |
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease | 2013 |
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Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico
|
Nature | 2013 |
|
The Role of Sphingolipids and (Dihydro)Ceramide Synthase 5 in Diabetic Cardiomyopathy
Sarah Russo, Catalin Baicu, An Van Laer, Tuoyu Geng, Harinath Kasiganesan, Michael R. Zile, L. Ashley Cowart |
Journal of Clinical Investigation | 2012 |
|
Obesity-related alterations in cardiac lipid profile and nondipping blood pressure pattern during transition to diastolic dysfunction in male db/db mice
VG Demarco, DA Ford, EJ Henriksen, AR Aroor, MS Johnson, J Habibi, L Ma, M Yang, CJ Albert, JW Lally, CA Ford, M Prasannarong, MR Hayden, AT Whaley-Connell, JR Sowers |
Endocrinology | 2012 |
|
Novel biomarkers for pre-diabetes identified by metabolomics
R Wang-Sattler, Z Yu, C Herder, AC Messias, A Floegel, Y He, K Heim, M Campillos, C Holzapfel, B Thorand, H Grallert, T Xu, E Bader, C Huth, K Mittelstrass, A Döring, C Meisinger, C Gieger, C Prehn, W Roemisch-Margl, M Carstensen, L Xie, H Yamanaka-Okumura, G Xing, U Ceglarek, J Thiery, G Giani, H Lickert, X Lin, Y Li, H Boeing, HG Joost, MH de Angelis, W Rathmann, K Suhre, H Prokisch, A Peters, T Meitinger, M Roden, HE Wichmann, T Pischon, J Adamski, T Illig |
Molecular Systems Biology | 2012 |
|
Plasma Lysophosphatidylcholine Levels Are Reduced in Obesity and Type 2 Diabetes
MN Barber, S Risis, C Yang, PJ Meikle, M Staples, MA Febbraio, CR Bruce |
PloS one | 2012 |
|
Shotgun Lipidomics by Sequential Precursor Ion Fragmentation on a Hybrid Quadrupole Time-of-Flight Mass Spectrometer
B Simons, D Kauhanen, T Sylvänne, K Tarasov, E Duchoslav, K Ekroos |
Metabolites | 2012 |
|
Obesity and psychotic disorders: uncovering common mechanisms through metabolomics
M Oresic |
Disease models & mechanisms | 2012 |
|
Fish Oil Supplementation Alters the Plasma Lipidomic Profile and Increases Long-Chain PUFAs of Phospholipids and Triglycerides in Healthy Subjects
I Ottestad, S Hassani, GI Borge, A Kohler, G Vogt, T Hyötyläinen, M Orešič, KW Brønner, KB Holven, SM Ulven, MC Myhrstad |
PloS one | 2012 |
|
Metabolic consequences of mitochondrial coenzyme A deficiency in patients with PANK2 mutations
V Leoni, L Strittmatter, G Zorzi, F Zibordi, S Dusi, B Garavaglia, P Venco, C Caccia, AL Souza, A Deik, CB Clish, M Rimoldi, E Ciusani, E Bertini, N Nardocci, VK Mootha, V Tiranti |
Molecular Genetics and Metabolism | 2012 |
|
A short-term diet and exercise intervention ameliorates inflammation and markers of metabolic health in overweight/obese children
A Izadpanah, RJ Barnard, AJ Almeda, GC Baldwin, SA Bridges, ER Shellman, CF Burant, CK Roberts |
American journal of physiology. Endocrinology and metabolism | 2012 |
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Metabolomics in the studies of islet autoimmunity and type 1 diabetes
M Oresic |
The review of diabetic studies : RDS | 2012 |
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Mapping the regioisomeric distribution of fatty acids in triacylglycerols by hybrid mass spectrometry
K Nagy, L Sandoz, F Destaillats, O Schafer |
Journal of lipid research | 2012 |
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Identification of serum metabolites associated with risk of type 2 diabetes using a targeted metabolomic approach
A Floegel, N Stefan, Z Yu, K Mühlenbruch, D Drogan, HG Joost, A Fritsche, HU Häring, MH de Angelis, A Peters, M Roden, C Prehn, R Wang-Sattler, T Illig, MB Schulze, J Adamski, H Boeing, T Pischon |
Diabetes | 2012 |
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Metabolomic prediction of diabetes and cardiovascular risk
S Dagogo-Jack |
Medical Principles and Practice | 2012 |
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Circulating metabolite predictors of glycemia in middle-aged men and women
P Würtz, M Tiainen, VP Mäkinen, AJ Kangas, P Soininen, J Saltevo, S Keinänen-Kiukaanniemi, P Mäntyselkä, T Lehtimäki, M Laakso, A Jula, M Kähönen, M Vanhala, M Ala-Korpela |
Diabetes care | 2012 |
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Metabolic signatures of insulin resistance in 7,098 young adults
P Würtz, VP Mäkinen, P Soininen, AJ Kangas, T Tukiainen, J Kettunen, MJ Savolainen, T Tammelin, JS Viikari, T Rönnemaa, M Kähönen, T Lehtimäki, S Ripatti, OT Raitakari, MR Järvelin, M Ala-Korpela |
Diabetes | 2012 |
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Perspectives on Systems Biology Applications in Diabetic Kidney Disease
CV Komorowsky, FC 3rd, S Pennathur, M Kretzler |
Journal of Cardiovascular Translational Research | 2012 |
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Metabolic Signature of Chronic Kidney Disease: the search continues
AV Mathew, S Pennathur |
American journal of kidney diseases : the official journal of the National Kidney Foundation | 2012 |
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Inflammatory-Induced Hibernation in the Fetus: Priming of Fetal Sheep Metabolism Correlates with Developmental Brain Injury
M Keller, DP Enot, MP Hodson, EI Igwe, HP Deigner, J Dean, H Bolouri, H Hagberg, C Mallard |
PloS one | 2011 |
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Serum Lipidomics Profiling using LC-MS and High Energy Collisional Dissociation Fragmentation: Focus on Triglyceride Detection and Characterization
SS Bird, VR Marur, MJ Sniatynski, HK Greenberg, BS Kristal |
Analytical Chemistry | 2011 |
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