Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • Vascular Malformations (Apr 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact

Citations to this article

Nociceptors: the sensors of the pain pathway
Adrienne E. Dubin, Ardem Patapoutian
Adrienne E. Dubin, Ardem Patapoutian
Published November 1, 2010
Citation Information: J Clin Invest. 2010;120(11):3760-3772. https://doi.org/10.1172/JCI42843.
View: Text | PDF
Review Series Article has an altmetric score of 903

Nociceptors: the sensors of the pain pathway

  • Text
  • PDF
Abstract

Specialized peripheral sensory neurons known as nociceptors alert us to potentially damaging stimuli at the skin by detecting extremes in temperature and pressure and injury-related chemicals, and transducing these stimuli into long-ranging electrical signals that are relayed to higher brain centers. The activation of functionally distinct cutaneous nociceptor populations and the processing of information they convey provide a rich diversity of pain qualities. Current work in this field is providing researchers with a more thorough understanding of nociceptor cell biology at molecular and systems levels and insight that will allow the targeted design of novel pain therapeutics.

Authors

Adrienne E. Dubin, Ardem Patapoutian

×

Total citations by year

Year: 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Total
Citations: 25 79 57 53 62 57 32 34 23 20 13 16 7 8 1 2 1 490
Citation information
This citation data is accumulated from CrossRef, which receives citation information from participating publishers, including this journal. Not all publishers participate in CrossRef, so this information is not comprehensive. Additionally, data may not reflect the most current citations to this article, and the data may differ from citation information available from other sources (for example, Google Scholar, Web of Science, and Scopus).

Citations to this article (490)

Title and authors Publication Year
PCSK9 deficiency promotes the development of peripheral neuropathy
Ali Jaafar, Aurélie Paulo-Ramos, Guillaume Rastoldo, Bryan Veeren, Cynthia Planesse, Matthieu Bringart, Philippe Rondeau, Olivier Meilhac, Gilles Lambert, Steeve Bourane
JCI insight 2025
An organic electrochemical neuron for a neuromorphic perception system
Yao Y, Pankow RM, Huang W, Wu C, Gao L, Cho Y, Chen J, Zhang D, Sharma S, Liu X, Wang Y, Peng B, Chung S, Cho K, Fabiano S, Ye Z, Ping J, Marks TJ, Facchetti A
Proceedings of the National Academy of Sciences of the United States of America 2025
Multidimensional free shape-morphing flexible neuromorphic devices with regulation at arbitrary points
Liu J, Jiang C, Yu Q, Ni Y, Yu C, Xu W
Nature Communications 2025
Linking heartbeats with the cortical network dynamics involved in self-social touch distinction
Candia-Rivera D, de Vico Fallani F, Boehme R, Salamone PC
Communications Biology 2025
Pain Perception Threshold in Young High-Altitude Natives After Acute Exposure to Severe Hypoxic Conditions
Vilca-Coaquira KM, Calisaya-Huacasi AG, Tejada-Flores J, Tintaya-Ramos HO, Quispe-Trujillo MM, Quispe-Humpiri SA, Rojas-Chambilla RA, Peña-Vicuña GF, Granara AS, Lens Sardón LF, Flores-Paredes A, Yang M, Viscor G, Zirena IH
Oxygen (Basel, Switzerland) 2025
Phytochemical-based therapeutics from traditional eastern medicine: analgesic effects and ion channel modulation
Kim SE, Chung G, Kim SK
Frontiers in Pain Research 2025
Procedure for Reliable and Long-Lasting Ex Vivo Recordings of Sciatic Nerve Activity in Mice
Berkowitz S, Goldberg Z, Dori A, Maggio N, Shavit-Stein E, Devaux JJ
Bio-protocol 2025
Selective promotion of sensory innervation–mediated immunoregulation for tissue repair
Xu K, Wu K, Chen L, Zhao Y, Li H, Lin N, Ye Z, Xu J, Huang D, Huang X
Science Advances 2025
Central GABAergic neuromodulation of nocifensive behaviors in bumble bees
Pasquini E, Brouwer J, Di Rollo V, Baracchi D, Messina A, Frasnelli E
iScience 2025
Parameter optimisation for mitigating somatosensory confounds during transcranial ultrasonic stimulation
Kop BR, de Jong L, Pauly KB, den Ouden HE, Verhagen L
bioRxiv 2025
Targeting PI3K-mTOR signaling in the anterior cingulate cortex improves emotional behavior, and locomotor activity in rats with bone cancer pain
Liu S, Zhu R, Zhang Y, Jiang Z, Chen Y, Song Q, Wang F
Annals of Medicine and Surgery 2025
Effectiveness of intravenous lidocaine in treatment of burn pain: a systematic review and meta-analysis of randomzed controlled trials
Elgadi A, Mohmed A, Elbadawi MH, Mohamed Elawad SO, Elamin MY, Elhaj NB, Elsadig A, Abdallah H
Annals of Medicine and Surgery 2025
Antagonist actions of CMK-1/CaMKI and TAX-6/calcineurin along the C. elegans thermal avoidance circuit orchestrate adaptation of nociceptive response to repeated stimuli
Rudgalvyte M, Hu Z, Kressler D, Dengjel J, Glauser DA
eLife 2025
Reflecting on Cancer Pain as Constant Acute Pain, not Chronic Pain. 'Known Knowns, Known Unknowns, Unknown Unknowns'.
Waldron D, Levins K, Murphy D, McCarthy M, Gorey D, Ryan K, Mannion E, Nicholas BM, Brannagáin DÓ, Reilly L, Gaffney L, Molony B, Healy M, Molony J, Dickenson A
Current oncology reports 2025
Sculpting excitable membranes: voltage-gated ion channel delivery and distribution.
Tyagi S, Higerd-Rusli GP, Akin EJ, Waxman SG, Dib-Hajj SD
Nature reviews. Neuroscience 2025
Clinical Evaluation of the Temperature Dependence of Subcutaneous Injection Experience in Healthy Volunteers.
Shi G, Shih H, Parker J, Patel H, Sirkar R, Sree V, Collins D
Pharmaceutical research 2025
Implications of nociceptor receptors and immune modulation: emerging therapeutic targets for autoimmune diseases.
Fatima SA, Akhtar B, Sharif A, Khan MI, Shahid M, Anjum F, Hussain F, Mobashar A, Ashraf M
Inflammopharmacology 2025
Microbiota-neuroepithelial signalling across the gut-brain axis.
Ohara TE, Hsiao EY
Nature reviews. Microbiology 2025
The effect of Jintiange capsules on pain in patients with primary osteoporosis: a systematic review and meta-analysis.
Li W, Ye B, Meng S, Huang Z, Jiang X, Qie F, Liu Y, Shi X, Li M
BMC musculoskeletal disorders 2025
Corneal Sensory Receptors and Pharmacological Therapies to Modulate Ocular Pain
Park R, Spritz S, Zeng AY, Erukulla R, Zavala D, Merchant T, Gascon A, Jung R, Bigit B, Azar DT, Chang JH, Jalilian E, Djalilian AR, Guaiquil VH, Rosenblatt MI
International Journal of Molecular Sciences 2025
Neuro-immune crosstalk in cancer: mechanisms and therapeutic implications
Pu T, Sun J, Ren G, Li H
Signal Transduction and Targeted Therapy 2025
Regulatory Action of Calcium and Calcium Channels in Pain Pathways
Zhang Y, Shannonhouse J, Son H, Park JT, Kim YS
International Journal of Biological Sciences 2025
High-Reliability Thermoreceptors with Minimal Temporal and Spatial Variations Through Photo-Induced Patterning Thermoelectrics
Du C, Hu Y, Xiao X, Manshaii F, Liang L, Chen J, Chen G
Nano-Micro Letters 2025
Opposite regulation of medullary pain–related projection neuron excitability in acute and chronic pain
Title B, Velasco E, Engelmayer N, Rayi PR, Yanai R, Hart S, Katz B, Lev S, Yarom Y, Binshtok AM
Science Advances 2025
Short-term effects of transcranial direct current stimulation on pain sensitivity, emotional and cognitive processes in non-suicidal self-injury: a randomised controlled trial
Lei C, Qu D, Chong D, Yi Y, Wu W, Tu Y, Chen R
General Psychiatry 2025
Can instrumentation kinematics affect postoperative pain and substance P levels? A randomized controlled trial.
Abdel-Baset ST, Fahmy SH, Obeid MF
BMC oral health 2024
A review of dorsal root ganglia and primary sensory neuron plasticity mediating inflammatory and chronic neuropathic pain
Jang K, Garraway SM
Neurobiology of Pain 2024
Isolectin B4 (IB4)-conjugated streptavidin for the selective knockdown of proteins in IB4-positive (+) nociceptors.
Bogen O, Araldi D, Sucher A, Kober K, Ohara PT, Levine JD
Molecular Pain 2024
Psycho-Neuroendocrinology in the Rehabilitation Field: Focus on the Complex Interplay between Stress and Pain
Bonanno M, Papa D, Cerasa A, Maggio MG, Calabrò RS
Medicina 2024
Alcohol use and the pain system
Vigorito M, Chang SL
2024
From pain to tumor immunity: influence of peripheral sensory neurons in cancer
Mardelle U, Bretaud N, Daher C, Feuillet V
Frontiers in immunology 2024
Poor lumbar spine coordination in acute low back pain predicts persistent long-term pain and disability.
Alshehri MA, van den Hoorn W, Klyne DM, van Dieën JH, Cholewicki J, Hodges PW
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 2024
Caldendrin Is a Repressor of PIEZO2 Channels and Touch Sensation in Mice.
Lopez JA, Romero LO, Kaung WL, Maddox JW, Vásquez V, Lee A
The Journal of neuroscience : the official journal of the Society for Neuroscience 2024
A mouse DRG genetic toolkit reveals morphological and physiological diversity of somatosensory neuron subtypes
Qi L, Iskols M, Shi D, Reddy P, Walker C, Lezgiyeva K, Voisin T, Pawlak M, Kuchroo VK, Chiu I, Ginty DD, Sharma N
Cell 2024
Compartment-specific regulation of NaV1.7 in sensory neurons after acute exposure to TNF-α
Tyagi S, Higerd-Rusli GP, Ghovanloo MR, Dib-Hajj F, Zhao P, Liu S, Kim DH, Shim JS, Park KS, Waxman SG, Choi JS, Dib-Hajj SD
Cell Reports 2024
CGRP sensory neurons promote tissue healing via neutrophils and macrophages.
Lu YZ, Nayer B, Singh SK, Alshoubaki YK, Yuan E, Park AJ, Maruyama K, Akira S, Martino MM
Nature 2024
Intradermal methylene blue analgesic application in posthemorrhoidectomy pain management: a randomized controlled trial
Azhough R, Jalali P, Dashti MR, Taher S, Aghajani A
Frontiers in Surgery 2024
Emerging Molecular and Synaptic Targets for the Management of Chronic Pain Caused by Systemic Lupus Erythematosus.
Weng HR
International journal of molecular sciences 2024
Female-selective mechanisms promoting migraine
Singh S, Kopruszinski CM, Watanabe M, Dodick DW, Navratilova E, Porreca F
The Journal of Headache and Pain 2024
Evaluation of force pain thresholds to ensure collision safety in worker-robot collaborative operations
Han D, Park MY, Choi J, Shin H, Behrens R, Rhim S
Frontiers in Robotics and AI 2024
A challenging diagnosis of chronic osteomyelitis in a child with congenital insensitivity to pain: a case report
Kamil H, Alassri R, Albelal D, Alassri AB, Martini N, Mahmod J
Annals of Medicine and Surgery 2024
Does pain intensity after total knee arthroplasty depend on somatosensory functioning in knee osteoarthritis patients? A prospective cohort study.
Vervullens S, Meert L, Smeets RJEM, Verbrugghe J, Verdonk P, Meeus M
Clinical Rheumatology 2024
Unraveling the Connection: Pain and Endoplasmic Reticulum Stress.
Kawanaka R, Jin H, Aoe T
International journal of molecular sciences 2024
Targeting TRPV4 Channels for Cancer Pain Relief.
Antoniazzi CTD, Ruviaro NA, Peres DS, Rodrigues P, Viero FT, Trevisan G
Cancers 2024
[Sequence variants of unknown significance in small fiber neuropathy : Characterization of a heterogeneous patient population].
Meyer Zu Altenschildesche C, Egenolf N, Lischka A, Üçeyler N
2024
GnRH peripherally modulates nociceptor functions, exacerbating mechanical pain.
Zheng H, Kim M, Kim C, Kim Y, Cho PS, Lim JY, Lee H, Yun HI, Choi J, Hwang SW
Frontiers in molecular neuroscience 2024
The Surgical Stress Response and Anesthesia: A Narrative Review
Ivascu R, Torsin LI, Hostiuc L, Nitipir C, Corneci D, Dutu M
Journal of Clinical Medicine 2024
Vertebrate behavioral thermoregulation: knowledge and future directions
Cutler B, Haesemeyer M
Neurophotonics 2024
Noise or signal? Spontaneous activity of dorsal horn neurons: patterns and function in health and disease.
Lucas-Romero J, Rivera-Arconada I, Lopez-Garcia JA
2024
Biomimetic Materials for Skin Tissue Regeneration and Electronic Skin.
Youn S, Ki MR, Abdelhamid MAA, Pack SP
2024
Brain-Derived Neurotrophic Factor, Nociception, and Pain.
Merighi A
Biomolecules 2024
Age-dependent small fiber neuropathy: Mechanistic insights from animal models.
Taub DG, Woolf CJ
Experimental Neurology 2024
Pathology of pain and its implications for therapeutic interventions
Cao B, Xu Q, Shi Y, Zhao R, Li H, Zheng J, Liu F, Wan Y, Wei B
Signal Transduction and Targeted Therapy 2024
Novel dental anesthetic and associated devices: a scoping review
Min KH, Morse Z
Journal of Dental Anesthesia and Pain Medicine 2024
Functional remodeling of presynaptic voltage-gated calcium channels in superficial layers of the dorsal horn during neuropathic pain
Ferron L, Harding EK, Gandini MA, Brideau C, Stys PK, Zamponi GW
iScience 2024
Evaluating the Potential of Green Light Exposure on Nociception-A Mini Review.
Qaiser H, Uzair M, Arshad M, Zafar A, Bashir S
CNS & neurological disorders drug targets 2024
Substance P’s Impact on Chronic Pain and Psychiatric Conditions—A Narrative Review
Humes C, Sic A, Knezevic NN
International journal of molecular sciences 2024
Post-operative pain after root canal preparation with different apical finishing sizes a triple blinded split mouth clinical trial
Kataia MM, Kataia EM, Khalil HF, Seoud MA
BMC oral health 2024
Advanced Neuromorphic Applications Enabled by Synaptic Ion‐Gating Vertical Transistors
Merces L, Ferro LM, Nawaz A, Sonar P
Advanced Science 2024
Prostaglandin E2 depolarises sensory axons in vitro in an ANO1 and Nav1.8 dependent manner
Kimourtzis G, Rangwani N, Jenkins BJ, Jani S, McNaughton PA, Raouf R
Scientific Reports 2024
Does Topical Capsaicin Affect the Central Nervous System in Neuropathic Pain? A Narrative Review
Alalami K, Goff J, Grimson H, Martin O, McDonald E, Mirza T, Mistry D, Ofodile A, Raja S, Shaker T, Sleibi D, Forget P
Pharmaceuticals 2024
Comparison of Thermal and Mechanical Pain Testing Modalities in Sprague Dawley and Fischer 344 Rats (Rattus norvegicus)
McNew JF, Davis DJ, Grimsrud KN, Bryda EC
Comparative medicine 2024
Efficacy and safety of diclofenac suppository for postoperative pain relief after diagnostic hystero-laparoscopy and dye test: A double-blind, placebo-controlled, randomized trial
Okam PC, Ikechebelu JI, Eleje GU, Albert IC, Okpala BC, Okam CF, Nwajiaku LA, Joe-Ikechebelu NN, Ezeigwe CO, Chigbo CG, Okafor CG
2024
Novel insight into atogepant mechanisms of action in migraine prevention
Melo-Carrillo A, Strassman AM, Broide R, Adams A, Dabruzzo B, Brin M, Burstein R
Brain : a journal of neurology 2024
The Influence of Sex Steroid Hormone Fluctuations on Capsaicin-Induced Pain and TRPV1 Expression
Mota-Carrillo E, Juárez-Contreras R, González-Ramírez R, Luis E, Morales-Lázaro SL
International journal of molecular sciences 2024
Antiferromagnetic artificial neuron modeling of the withdrawal reflex.
Bradley H, Quach L, Louis S, Tyberkevych V
Journal of Computational Neuroscience 2024
Persistent changes in nociceptor translatomes govern hyperalgesic priming in mouse models
Sankaranarayanan I, Kume M, Mohammed A, Mwirigi JM, Inturi NN, Munro G, Petersen KA, Tavares-Ferreira D, Price TJ
bioRxiv 2024
Daidzein ameliorates peripheral neuropathy in Sprague Dawley rats
Laddha AP, Kulkarni YA
Frontiers in Pharmacology 2024
Lung-innervating nociceptor sensory neurons promote pneumonic sepsis during carbapenem-resistant Klebsiella pneumoniae lung infection
Joshi PR, Adhikari S, Onah C, Carrier C, Judd A, Mack M, Baral P
Science Advances 2024
CGRP inhibits SARS-CoV-2 infection of bronchial epithelial cells, and its pulmonary levels correlate with viral clearance in critical COVID-19 patients
Barbosa Bomfim CC, Génin H, Cottoignies-Callamarte A, Gallois-Montbrun S, Murigneux E, Sams A, Rosenberg AR, Belouzard S, Dubuisson J, Kosminder O, Pène F, Terrier B, Bomsel M, Ganor Y
Journal of Virology 2024
Drugs used for pain management in gastrointestinal surgery and their implications
Shukla A, Chaudhary R, Nayyar N, Gupta B
World Journal of Gastrointestinal Pharmacology and Therapeutics 2024
Opioid and Cannabinoid Systems in Pain: Emerging Molecular Mechanisms and Use in Clinical Practice, Health, and Fitness
Secondulfo C, Mazzeo F, Pastorino GM, Vicidomini A, Meccariello R, Operto FF
International Journal of Molecular Sciences 2024
Application of the IASP Grading System to Identify Underlying Pain Mechanisms in Patients With Knee Osteoarthritis: A Prospective Cohort Study
Vervullens S, Meert L, Meeus M, Heusdens CH, Verdonk P, Foubert A, Abatih E, Durnez L, Verbrugghe J, Smeets RJ
The Clinical Journal of Pain 2024
Role of TRPA1 in Painful Cold Hypersensitivity.
Nakagawa T, Kaneko S
Advances in experimental medicine and biology 2024
Mott neurons with dual thermal dynamics for spatiotemporal computing.
Kim G, In JH, Lee Y, Rhee H, Park W, Song H, Park J, Jeon JB, Brown TD, Talin AA, Kumar S, Kim KM
Nature materials 2024
Chronic pain in the elderly: Exploring cellular and molecular mechanisms and therapeutic perspectives
García-Domínguez M
Frontiers in Aging 2024
Neuroimmune Recognition of Allergens
Chiu IM, Sokol CL
Current opinion in immunology 2024
Embedded Hybrid‐Dimensional Heterointerface for Filament Modulation in 2D Material‐Based Artificial Nociceptor
Huang C, Cheng T, Wu C, Chen K, Wu T, Chou Y
Advanced Science 2024
Pain research in a petri dish? Advantages and limitations of neuro-glial primary cell cultures from structures of the nociceptive system
Leisengang S
Brain, Behavior, & Immunity - Health 2024
Monolithically integrated neuromorphic electronic skin for biomimetic radiation shielding.
Lee JM, Cho SW, Jo C, Yang SH, Kim J, Kim DY, Jo JW, Park JS, Kim YH, Park SK
Science advances 2024
Cytokines reprogram airway sensory neurons in asthma.
Crosson T, Bhat S, Wang JC, Salaun C, Fontaine E, Roversi K, Herzog H, Rafei M, Blunck R, Talbot S
bioRxiv : the preprint server for biology 2024
Ketamine and α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid (AMPA) Receptor Potentiation in the Somatosensory Cortex: A Comprehensive Review.
Das K, Sen J, Borode AS
Cureus 2024
Modulatory Impact of Oxidative Stress on Action Potentials in Pathophysiological States: A Comprehensive Review.
Mahapatra C, Thakkar R, Kumar R
Antioxidants (Basel, Switzerland) 2024
A Proposal for a Noxious Stimuli-Free, Moderate-Intensity Treadmill Running Protocol to Improve Aerobic Performance in Experimental Research on Rats.
de Assis GG, de Souza EON, de Almeida-Neto PF, Ceylan Hİ, Bragazzi NL
Metabolites 2024
Dermal TRPV1 innervations engage a macrophage- and fibroblast-containing pathway to activate hair growth in mice.
Ben-Shaanan TL, Knöpper K, Duan L, Liu R, Taglinao H, Xu Y, An J, Plikus MV, Cyster JG
Developmental cell 2024
Differences in self-reported signs related to central sensitization and pressure pain threshold related to knee osteoarthritis and sarcopenia.
Imai R, Tanaka S, Kubo T, Hida M, Nakao H, Imaoka M, Nishigami T
European geriatric medicine 2024
Adaptive Autonomic and Neuroplastic Control in Diabetic Neuropathy: A Narrative Review.
Marsili F, Potgieter P, Birkill CF
Current diabetes reviews 2024
A Biomimetic Nociceptor Based on a Vertical Multigate, Multichannel Neuromorphic Transistor
Xu H, Shang DS, Tang J, Luo Q, Xu X, Liang R, Pan L, Gao B, Wang Q, He D, Liu Q, Liu M, Qian H, Wu H
ACS Nano 2024
A microfluidic model of the first sensory synapse for analgesic target discovery.
Kimourtzis G, Raouf R
Molecular pain 2024
Selective nociceptive modulation using a novel prototype of transcutaneous kilohertz high-frequency alternating current stimulation: a crossover double-blind randomized sham-controlled trial
Fernández-Pérez JJ, Serrano-Muñoz D, Gómez-Soriano J, Álvarez DM, Avendaño-Coy J
Journal of NeuroEngineering and Rehabilitation 2024
The gut-brain axis and pain signalling mechanisms in the gastrointestinal tract.
Meerschaert KA, Chiu IM
Nature reviews. Gastroenterology & hepatology 2024
Pathophysiology of Pain and Mechanisms of Neuromodulation: A Narrative Review (A Neuron Project)
Karcz M, Abd-Elsayed A, Chakravarthy K, Aman MM, Strand N, Malinowski MN, Latif U, Dickerson D, Suvar T, Lubenow T, Peskin E, D\u2019Souza R, Cornidez E, Dudas A, Lam C, Farrell II M, Sim GY, Sebai M, Garcia R, Bracero L, Ibrahim Y, Mahmood SJ, Lawandy M, Jimenez D, Shahgholi L, Sochacki K, Ramadan ME, Tieppo Francio V, Sayed D, Deer T
Journal of Pain Research 2024
Putative Nociceptive Responses in a Decapod Crustacean: The Shore Crab (Carcinus maenas)
Kasiouras E, Hubbard PC, Gräns A, Sneddon LU
Biology 2024
The peripheral neuroimmune system
Song K, Kim BS
Journal of Leukocyte Biology 2024
The Role of Mechanosensitive Piezo Channels in Chronic Pain
Wan Y, Zhou J, Li H
Journal of Pain Research 2024
Assessing the effects of fluorine-free and PFAS-containing firefighting foams on development and behavioral responses using a zebrafish-based platform
Niaz K, McAtee D, Adhikari P, Rollefson P, Ateia M, Abdelmoneim A
Chemosphere 2024
Greater recalled pain and movement-evoked pain are associated with longer 400-meter walk and repeat stair climb time: the Study of Muscle, Mobility and Aging
Mau T, Barnes HN, Simon CB, Hetherington-Rauth M, Bauer SR, Strotmeyer ES, Lane NE, Rowbotham MC, Weaver AA, Blackwell TL, Cai Y, Glynn NW, Goodpaster BH, Cummings SR, Newman AB, Cawthon PM, Kritchevsky SB
medRxiv 2024
Molecular regulation of axon termination in mechanosensory neurons
Desbois M, Grill B
Development (Cambridge, England) 2024
Immediate Effects of Distinct Intensities of Transcutaneous Spinal Direct Current Stimulation on Chronic Pain: A Randomized Controlled Trial
Ferreira KR, Macedo MD, Alves AL, Esquírio AF, Botim BR, Jacob GS, dos Santos ME, Gama GL, Barbosa MC, Barbosa AW
NeuroSci 2024
Examining Changes in Pain Sensitivity Following 8 Minutes of Cycling at Varying Exercise Intensities
ANTONIO BB, STOUT JR, STERNER DA, FUKUDA DH, ANDERSON AW
International Journal of Exercise Science 2024
Battling pain from osteoarthritis: causing novel cell death: Battling pain from osteoarthritis
Zhang Y, Tao H, Zhang L, Li X, Shi Y, Sun W, Chen W, Zhao Y, Wang L, Yang X, Gu C
Acta Biochimica et Biophysica Sinica 2024
Neuroimmune circuits in the plaque and bone marrow regulate atherosclerosis
Gerhardt T, Huynh P, McAlpine CS
Cardiovascular Research 2024
An overview of the non‐procedural treatment options for peripheral neuropathic pain
Zeldin ER, Goddard AR, Boyle MS, Madathil RL, Rosenvall E, Majithia KA, Morrison EJ
Muscle & Nerve 2024
A male-specific mechanism of meningeal nociceptor sensitization promoting migraine headache
Kopruszinski CM, Lee G, Martin LK, Barber KR, Moutal A, Dodick DW, Navratilova E, Porreca F
Cephalalgia : an international journal of headache 2024
Mechanism and effects of STING–IFN-I pathway on nociception: A narrative review
Yang J, Ding H, Shuai B, Zhang Y, Zhang Y
Frontiers in molecular neuroscience 2023
All oxide based flexible multi-folded invisible synapse as vision photo-receptor
Chen PX, Panda D, Tseng TY
Scientific Reports 2023
The nociceptive response induced by different classes of Tityus serrulatus neurotoxins: The important role of Ts5 in venom-induced nociception
Cerni F, Oliveira I, Cordeiro F, Bordon K, Ferreira I, Monteiro W, Arantes E, Cunha T, Pucca M
PLoS neglected tropical diseases 2023
Toward the unknown: consciousness and pain
Ambron R
Neuroscience of Consciousness 2023
Mechanisms of Transmission and Processing of Pain: A Narrative Review
Di Maio G, Villano I, Ilardi CR, Messina A, Monda V, Iodice AC, Porro C, Panaro MA, Chieffi S, Messina G, Monda M, La Marra M
International journal of environmental research and public health 2023
Evaluation of Nociception during Pediatric Surgery: A Topical Review.
Bertolizio G, Garbin M, Ingelmo PM
Journal of Personalized Medicine 2023
Measuring pain and nociception: Through the glasses of a computational scientist. Transdisciplinary overview of methods
Kutafina E, Becker S, Namer B
2023
Biological function simulation in neuromorphic devices: from synapse and neuron to behavior
Chen H, Li H, Ma T, Han S, Zhao Q
Science and Technology of Advanced Materials 2023
Can Opioid-Free Anaesthesia Be Personalised? A Narrative Review
Goff J, Hina M, Malik N, McLardy H, Reilly F, Robertson M, Ruddy L, Willox F, Forget P
Journal of Personalized Medicine 2023
Control of myeloid cell functions by nociceptors
Hanč P, Messou MA, Wang Y, von Andrian UH
Frontiers in immunology 2023
Developmental exposure to the pesticide malathion enhances expression of Prdm12, a regulator of nociceptor development, in Xenopus laevis.
Donoso V, Whitson J, Lom B
microPublication biology 2023
Excitatory and inhibitory neuronal signaling in inflammatory and diabetic neuropathic pain.
Breitinger U, Breitinger HG
Molecular Medicine 2023
Sonic Hedgehog Signaling Pathway: A Role in Pain Processing.
Zheng G, Ren J, Shang L, Bao Y
Neurochemical Research 2023
A systematic review of neurophysiological sensing for the assessment of acute pain.
Fernandez Rojas R, Brown N, Waddington G, Goecke R
2023
Self-assembled Innervated Vasculature-on-a-chip to Study Nociception
Kumar V, Kingsley D, Perikamana SM, Mogha P, Goodwin CR, Varghese S
Biofabrication 2023
A DRG genetic toolkit reveals molecular, morphological, and functional diversity of somatosensory neuron subtypes
Qi L, Iskols M, Shi D, Reddy P, Walker C, Lezgiyeva K, Voisin T, Pawlak M, Kuchroo VK, Chiu I, Ginty DD, Sharma N
2023
Interhemispheric neural characteristics of noxious mechano-nociceptive stimulation in the anterior cingulate cortex
Aminitabar A, Mirmoosavi M, Ghodrati MT, Shalchyan V
Frontiers in neural circuits 2023
Osteosarcopenia and Pain: Do We Have a Way Out?
Bonanni R, Gino Grillo S, Cariati I, Tranquillo L, Iundusi R, Gasbarra E, Tancredi V, Tarantino U
Biomedicines 2023
Identification of key factors driving inflammation-induced sensitization of muscle sensory neurons
Nagaraja S, Tewari SG, Reifman J
Frontiers in neuroscience 2023
IL-10/β-Endorphin-Mediated Neuroimmune Modulation on Microglia during Antinociception
Belo TC, Santos GX, da Silva BE, Rocha BL, Abdala DW, Freire LA, Rocha FS, Galdino G
Brain Sciences 2023
The Pharmacokinetics of Subcutaneous Methylnaltrexone Bromide in Rhesus Macaques (Macaca mulatta)
Jepkes S, Josee-Lemoy M, Knych H, de Lucena T, Ardeshir A, Stockinger DE
Journal of the American Association for Laboratory Animal Science : JAALAS 2023
Cardiovascular Brain Circuits
Mohanta SK, Yin C, Weber C, Godinho-Silva C, Veiga-Fernandes H, Xu QJ, Chang RB, Habenicht AJ
Circulation research 2023
Peripheral sensory neurons and non-neuronal cells express functional Piezo1 channels
Shin SM, Itson-Zoske B, Fan F, Gani U, Rahman M, Hogan QH, Yu H
Molecular Pain 2023
Remote targeted electrical stimulation
Webb T, Cheeniyil R, Wilson M, Kubanek J
Journal of Neural Engineering 2023
Oral Methadone versus Morphine IR for Patients with Cervical Cancer and Neuropathic Pain: A Prospective Randomised Controlled Trial
Adumala A, Palat G, Vajjala A, Brun E, Segerlantz M
Indian Journal of Palliative Care 2023
Comparison of Novel Wide-Field In Vivo Corneal Confocal Microscopy With Skin Biopsy for Assessing Peripheral Neuropathy in Type 2 Diabetes
Badian RA, Ekman L, Pripp AH, Utheim TP, Englund E, Dahlin LB, Rolandsson O, Lagali N
Diabetes 2023
Pungency Perception and the Interaction with Basic Taste Sensations: An Overview
He W, Liang L, Zhang Y
Foods 2023
A descending inhibitory mechanism of nociception mediated by an evolutionarily conserved neuropeptide system in Drosophila
Oikawa I, Kondo S, Hashimoto K, Yoshida A, Hamajima M, Tanimoto H, Furukubo-Tokunaga K, Honjo K
eLife 2023
Pain sensitivity differs between dog breeds but not in the way veterinarians believe.
Caddiell RMP, Cunningham RM, White PA, Lascelles BDX, Gruen ME
2023
Pain Evaluation and Treatment in Children: A Practical Approach
Sansone L, Gentile C, Grasso EA, Di Ludovico A, La Bella S, Chiarelli F, Breda L
Children 2023
I Feel! Therefore, I Am from Pain to Consciousness in DOC Patients
Riganello F, Tonin P, Soddu A
International journal of molecular sciences 2023
The effect of risperidone on behavioral reactions and gene expression of pro- and anti-inflammatory cytokines in neuropathic pain model induced by chronic constriction injury of the sciatic nerve in rat.
Haghighat Lari MM, Banafshe HR, Seyed Hosseini E, Haddad Kashani H
InflammoPharmacology 2023
Pharmacological Methods of Pain Management: Narrative Review of Medication Used
Alorfi NM
International journal of general medicine 2023
A new Hoxb8FlpO mouse line for intersectional approaches to dissect developmentally defined adult sensorimotor circuits.
Bohic M, Upadhyay A, Eisdorfer JT, Keating J, Simon RC, Briones BA, Azadegan C, Nacht HD, Oputa O, Martinez AM, Bethell BN, Gradwell MA, Romanienko P, Ramer MS, Stuber GD, Abraira VE
Frontiers in molecular neuroscience 2023
Anti-nociceptive and Anti-inflammatory Activities of Visnagin in Different Nociceptive and Inflammatory Mice Models.
Qi X, Aiyasamy K, Alenezi SK, Alanazi IM, Alshammari MS, Ibrahim IAA
Applied Biochemistry and Biotechnology 2023
Deep RNA-seq of male and female murine sensory neuron subtypes after nerve injury.
Barry AM, Zhao N, Yang X, Bennett DL, Baskozos G
PAIN 2023
Probing the Activation Mechanisms of Agonist DPI-287 to Delta-Opioid Receptor and Novel Agonists Using Ensemble-Based Virtual Screening with Molecular Dynamics Simulations
Dean E, Dominique A, Palillero A, Tran A, Paradis N, Wu C
ACS Omega 2023
A Comparative Evaluation of Intra-articular Bupivacaine vs Bupivacaine and Dexmedetomidine for Postoperative Analgesia in Arthroscopic Knee Surgeries
Paul A, Borkar A, Bhalerao N, Wanjari D
Cureus 2023
Compartmentalized primary cultures of dorsal root ganglion neurons to model peripheral pathophysiological conditions
Giorgi S, Lamberti A, Butrón L, Gross-Amat O, Alarcón-Alarcón D, Rodríguez-Cañas E, Fernández-Carvajal A, Ferrer-Montiel A
Molecular Pain 2023
Inflammatory Orofacial Pain Activates Peptidergic Neurons and Upregulates the Oxytocin Receptor Expression in Trigeminal Ganglion
Kemenesi-Gedei PB, Csabafi KA, Kis G
Biomedicines 2023
Stunning Compliance in Halal Slaughter: A Review of Current Scientific Knowledge
Sazili AQ, Kumar P, Hayat MN
2023
Mechanotransductive receptor Piezo1 as a promising target in the treatment of fibrosis diseases
Xu Y, Huang Y, Cheng X, Hu B, Jiang D, Wu L, Peng S, Hu J
Frontiers in Molecular Biosciences 2023
The Impact of the Nervous System on Arteries and the Heart: The Neuroimmune Cardiovascular Circuit Hypothesis.
Mohanta SK, Sun T, Lu S, Wang Z, Zhang X, Yin C, Weber C, Habenicht AJR
Cells 2023
Pain as a Guide in Glasgow Coma Scale Status for Neurological Assessment
Nallaluthan V, Tan GY, Murni MF, Saleh U, Abdul Halim S, Idris Z, Ghani AR, Abdullah JM
The Malaysian Journal of Medical Sciences : MJMS 2023
Predictive analytics identifies key factors driving hyperalgesic priming of muscle sensory neurons
Nagaraja S, Tewari SG, Reifman J
Frontiers in neuroscience 2023
GluCl.CreON enables selective inhibition of molecularly defined pain circuits
Middleton SJ, Hu H, Perez-Sanchez J, Zuberi S, McGrath Williams J, Weir GA, Bennett DL
PAIN 2023
A Manifesto in Defense of Pain Complexity: A Critical Review of Essential Insights in Pain Neuroscience
Párraga JP, Castellanos A
Journal of Clinical Medicine 2023
Exercise Therapy for Chronic Neck Pain: Tailoring Person-Centred Approaches within Contemporary Management
de Zoete RM
Journal of Clinical Medicine 2023
Bridging the Gap: Investigating the Link between Inflammasomes and Postoperative Cognitive Dysfunction
Zhang S, Liu C, Sun J, Li Y, Lu J, Xiong X, Hu L, Zhao H, Zhou H
Aging and disease 2023
NLRP3 inflammasome activation in sensory neurons promotes chronic inflammatory and osteoarthritis pain.
Silva Santos Ribeiro P, Willemen HLDM, Versteeg S, Martin Gil C, Eijkelkamp N
2023
Neurophysiology, Neuro-Immune Interactions, and Mechanobiology in Osteopathy in the Cranial Field: An Evidence-Informed Perspective for a Scientific Rationale
Barsotti N, Casini A, Chiera M, Lunghi C, Fornari M
Healthcare 2023
Effect of multidimensional physiotherapy on non-specific chronic low back pain: a randomized controlled trial.
Bemani S, Sarrafzadeh J, Dehkordi SN, Talebian S, Salehi R, Zarei J
Advances in rheumatology (London, England) 2023
Advancements in Understanding and Classifying Chronic Orofacial Pain: Key Insights from Biopsychosocial Models and International Classifications (ICHD-3, ICD-11, ICOP).
Canfora F, Ottaviani G, Calabria E, Pecoraro G, Leuci S, Coppola N, Sansone M, Rupel K, Biasotto M, Di Lenarda R, Mignogna MD, Adamo D
Biomedicines 2023
Reactive oxygen species (ROS)-mediated M1 macrophage-dependent nanomedicine remodels inflammatory microenvironment for osteoarthritis recession
Xue C, Tian J, Cui Z, Liu Y, Sun D, Xiong M, Yi N, Wang K, Li X, Wang Y, Xu H, Zhang W, Liang Q
Bioactive Materials 2023
Stem cells and pain.
da Silva MDV, Piva M, Martelossi-Cebinelli G, Stinglin Rosa Ribas M, Hoffmann Salles Bianchini B, K Heintz O, Casagrande R, Verri WA Jr
World journal of stem cells 2023
Artificial sensory system based on memristive devices
Kwon JY, Kim JE, Kim JS, Chun SY, Soh K, Yoon JH
2023
Tyrosine Kinase Receptor ErbB4 in Advillin-Positive Neurons Contributes to Inflammatory Pain Hypersensitivity in Mouse DRG.
Guo Z, Huang Q, Zhang W, Shi K, Yuan J, Qi S, Wang B, Li K, Li S, Gong J, Jing X, Liu Y, Tan G
Aging and disease 2023
A Natural History of Disease Framework for Improving the Prevention, Management, and Research on Post-viral Fatigue Syndrome and Other Forms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
S O'Boyle, L Nacul, F Nacul, K Mudie, C Kingdon, J Cliff, T Clark, H Dockrell, E Lacerda
Frontiers in Medicine 2022
Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider.
Finol-Urdaneta RK, Ziegman R, Dekan Z, McArthur JR, Heitmann S, Luna-Ramirez K, Tae HS, Mueller A, Starobova H, Chin YK, Wingerd JS, Undheim EAB, Cristofori-Armstrong B, Hill AP, Herzig V, King GF, Vetter I, Rash LD, Adams DJ, Alewood PF
Proceedings of the National Academy of Sciences 2022
fNIRS brain measures of ongoing nociception during surgical incisions under anesthesia.
Green S, Karunakaran KD, Labadie R, Kussman B, Mizrahi-Arnaud A, Morad AG, Berry D, Zurakowski D, Micheli L, Peng K, Borsook D
Neurophotonics 2022
Chronic Pain in Musculoskeletal Diseases: Do You Know Your Enemy?
Bonanni R, Cariati I, Tancredi V, Iundusi R, Gasbarra E, Tarantino U
Journal of Clinical Medicine 2022
Use of Physiologically Based Kinetic Modeling-Facilitated Reverse Dosimetry to Predict In Vivo Acute Toxicity of Tetrodotoxin in Rodents.
Noorlander A, Zhang M, van Ravenzwaay B, Rietjens IMCM
Toxicological sciences : an official journal of the Society of Toxicology 2022
Neuroimmune cardiovascular interfaces control atherosclerosis.
Mohanta SK, Peng L, Li Y, Lu S, Sun T, Carnevale L, Perrotta M, Ma Z, Förstera B, Stanic K, Zhang C, Zhang X, Szczepaniak P, Bianchini M, Saeed BR, Carnevale R, Hu D, Nosalski R, Pallante F, Beer M, Santovito D, Ertürk A, Mettenleiter TC, Klupp BG, Megens RTA, Steffens S, Pelisek J, Eckstein HH, Kleemann R, Habenicht L, Mallat Z, Michel JB, Bernhagen J, Dichgans M, D'Agostino G, Guzik TJ, Olofsson PS, Yin C, Weber C, Lembo G, Carnevale D, Habenicht AJR
Nature 2022
The Spino-Parabrachial Pathway for Itch.
Piyush Shah D, Barik A
Frontiers in neural circuits 2022
Regulation of Carcinogenesis by Sensory Neurons and Neuromediators.
Erin N, Shurin GV, Baraldi JH, Shurin MR
Cancers 2022
Towards bridging the translational gap by improved modeling of human nociception in health and disease.
Zeidler M, Kummer KK, Kress M
2022
The Energy Homeostasis Principle: A Naturalistic Approach to Explain the Emergence of Behavior
Vicencio-Jimenez S, Villalobos M, Maldonado PE, Vergara RC
Frontiers in systems neuroscience 2022
NGF Enhances CGRP Release Evoked by Capsaicin from Rat Trigeminal Neurons: Differential Inhibition by SNAP-25-Cleaving Proteases
Belinskaia M, Zurawski T, Kaza SK, Antoniazzi C, Dolly JO, Lawrence GW
International journal of molecular sciences 2022
Imaging the influence of peripheral TRPV1-signaling on cerebral nociceptive processing applying fMRI-based graph theory in a resiniferatoxin rat model
Wank I, Kutsche L, Kreitz S, Reeh P, Hess A
PloS one 2022
Potential Role of Yoga Intervention in the Management of Chronic Non-malignant Pain
Gupta S, Gautam S, Kumar U, Arora T, Dada R
Evidence-based complementary and alternative medicine : eCAM 2022
Different perspectives for monitoring nociception during general anesthesia.
Martinez-Vazquez P, Jensen EW
Korean Journal of Anesthesiology 2022
Current Challenges in the Management of Chronic Pelvic Pain in Women: From Bench to Bedside.
Siqueira-Campos VM, de Deus MSC, Poli-Neto OB, Rosa-E-Silva JC, de Deus JM, Conde DM
International journal of women's health 2022
The Slack Channel Deletion Causes Mechanical Pain Hypersensitivity in Mice.
Liu Y, Zhang FF, Song Y, Wang R, Zhang Q, Shen ZS, Zhang FF, Zhong DY, Wang XH, Guo Q, Tang QY, Zhang Z
Frontiers in molecular neuroscience 2022
Light-emitting diode phototherapy: pain relief and underlying mechanisms.
Zhang WW, Wang XY, Chu YX, Wang YQ
Lasers in Medical Science 2022
Thermal Properties of Warm- versus Heated-Needle Acupuncture
Jo HR, Choi SK, Sung WS, Lee SD, Lee BW, Kim EJ
Evidence-based complementary and alternative medicine : eCAM 2022
Tissue accumulation of neutrophil extracellular traps mediates muscle hyperalgesia in a mouse model
Suzuki K, Tsuchiya M, Yoshida S, Ogawa K, Chen W, Kanzaki M, Takahashi T, Fujita R, Li Y, Yabe Y, Aizawa T, Hagiwara Y
Scientific Reports 2022
Roadbumps at the Crossroads of Integrating Behavioral and In Vitro Approaches for Neurotoxicity Assessment
Harry GJ, McBride S, Witchey SK, Mhaouty-Kodja S, Trembleau A, Bridge M, Bencsik A
2022
Review of Perioperative Music Medicine: Mechanisms of Pain and Stress Reduction Around Surgery
Ginsberg JP, Raghunathan K, Bassi G, Ulloa L
Frontiers in Medicine 2022
Advancing the Understanding of Acupoint Sensitization and Plasticity Through Cutaneous C-Nociceptors
Cui X, Liu K, Gao X, Zhu B
Frontiers in neuroscience 2022
A Bioinspired Artificial Injury Response System Based on a Robust Polymer Memristor to Mimic a Sense of Pain, Sign of Injury, and Healing
Xu X, Cho EJ, Bekker L, Talin AA, Lee E, Pascall AJ, Worsley MA, Zhou J, Cook CC, Kuntz JD, Cho S, Orme CA
Advanced Science 2022
Nociceptors: Their Role in Body's Defenses, Tissue Specific Variations and Anatomical Update.
Nikolenko VN, Shelomentseva EM, Tsvetkova MM, Abdeeva EI, Giller DB, Babayeva JV, Achkasov EE, Gavryushova LV, Sinelnikov MY
Journal of pain research 2022
Transcriptional Alterations of Mouse Trigeminal Ganglion Neurons Following Orofacial Inflammation Revealed by Single-Cell Analysis
Liu Q, Mai L, Yang S, Jia S, Chu Y, He H, Fan W, Huang F
Frontiers in cellular neuroscience 2022
Reduced Motion External Defibrillation (RMD): Reduced Subject Motion with Equivalent Defibrillation Efficiency validated in Swine
Schmidt EJ, Elahi H, Meyer ES, Baumgaertner R, Neri L, Berger RD, Tandri H, Hunter DW, Cohen SP, Oberdier MT, Halperin HR
Heart rhythm : the official journal of the Heart Rhythm Society 2022
Neuroinflammation Involved in Diabetes-Related Pain and Itch
Fang XX, Wang H, Song HL, Wang J, Zhang ZJ
Frontiers in pharmacology 2022
In vivo Mouse Intervertebral Disc Degeneration Models and Their Utility as Translational Models of Clinical Discogenic Back Pain: A Comparative Review
Tang SN, Walter BA, Heimann MK, Gantt CC, Khan SN, Kokiko-Cochran ON, Askwith CC, Purmessur D
2022
Spatial transcriptomics of dorsal root ganglia identifies molecular signatures of human nociceptors.
Tavares-Ferreira D, Shiers S, Ray PR, Wangzhou A, Jeevakumar V, Sankaranarayanan I, Cervantes AM, Reese JC, Chamessian A, Copits BA, Dougherty PM, Gereau RW 4th, Burton MD, Dussor G, Price TJ
Science Translational Medicine 2022
Larval Zebrafish as a Model for Mechanistic Discovery in Mental Health.
Tan JXM, Ang RJW, Wee CL
Frontiers in molecular neuroscience 2022
Skin Injury Activates A Rapid TRPV1-dependent Antiviral Protein Response
Lei V, Handfield C, Kwock JT, Kirchner SJ, Lee MJ, Coates M, Wang K, Han Q, Wang Z, Powers JG, Wolfe S, Corcoran DL, Fanelli B, Dadlani M, Ji RR, Zhang JY, MacLeod AS
Journal of Investigative Dermatology 2022
The dawn has come for new therapeutics to treat atherosclerosis: Targeting neuroimmune cardiovascular interfaces in artery brain circuits.
Mohanta SK, Weber C, Yin C, Habenicht AJR
Clinical and Translational Medicine 2022
Ceratonia siliqua leaves ethanol extracts exert anti-nociceptive and anti-inflammatory effects
Alqudah A, Qnais EY, Wedyan MA, Oqal M, Alqudah M, AbuDalo R, AL-Hashimi N
Heliyon 2022
Interaction between the nervous and skeletal systems.
Xu J, Zhang Z, Zhao J, Meyers CA, Lee S, Qin Q, James AW
Frontiers in Cell and Developmental Biology 2022
From nociception to pain perception, possible implications of astrocytes.
Higinio-Rodríguez F, Rivera-Villaseñor A, Calero-Vargas I, López-Hidalgo M
Frontiers in cellular neuroscience 2022
How Temperature Influences Sleep.
Fan Y, Wang Y, Gu P, Han J, Tian Y
International journal of molecular sciences 2022
Intraoperative Assessment of Surgical Stress Response Using Nociception Monitor under General Anesthesia and Postoperative Complications: A Narrative Review.
Hirose M, Okutani H, Hashimoto K, Ueki R, Shimode N, Kariya N, Takao Y, Tatara T
Journal of Clinical Medicine 2022
Application of Electroencephalography in Preslaughter Management: A Review.
Kumar P, Abubakar AA, Sazili AQ, Kaka U, Goh YM
2022
Transcriptomic and proteomic profiling of NaV1.8-expressing mouse nociceptors.
Schmidt M, Sondermann JR, Gomez-Varela D, Çubuk C, Millet Q, Lewis MJ, Wood JN, Zhao J
Frontiers in molecular neuroscience 2022
Single-cell RNA sequencing reveals distinct transcriptional features of the purinergic signaling in mouse trigeminal ganglion.
Jia S, Liu J, Chu Y, Liu Q, Mai L, Fan W
Frontiers in molecular neuroscience 2022
Systemic Lipopolysaccharide Challenge Induces Inflammatory Changes in Rat Dorsal Root Ganglia: An Ex Vivo Study
Nürnberger F, Ott D, Claßen R, Rummel C, Roth J, Leisengang S
International journal of molecular sciences 2022
Relations between short-term memory and the within-subject variability of experimental pain intensity reports: Results from healthy and Fibromyalgia patients
Canaipa R, Khallouf A, Magalhães AR, Teodoro R, Pão-Mole V, Agostinho M, Pimentel-Santos F, Honigman L, Treister R
PloS one 2022
Local Anesthesia in Interventional Radiology
Li X, Trerotola SO
Seminars in interventional radiology 2022
Mechanoreceptor signal convergence and transformation in the dorsal horn flexibly shape a diversity of outputs to the brain.
Chirila AM, Rankin G, Tseng SY, Emanuel AJ, Chavez-Martinez CL, Zhang D, Harvey CD, Ginty DD
Cell 2022
Memristors with Nociceptor Characteristics Using Threshold Switching of Pt/HfO2/TaOx/TaN Devices
Park M, Jeon B, Park J, Kim S
Nanomaterials 2022
Rubbing Salt in the Wound: Molecular Evolutionary Analysis of Pain-Related Genes Reveals the Pain Adaptation of Cetaceans in Seawater.
Ding X, Yu F, He X, Xu S, Yang G, Ren W
2022
Mini review: The role of sensory innervation to subchondral bone in osteoarthritis pain
Morgan M, Nazemian V, Harrington K, Ivanusic JJ
Frontiers in Endocrinology 2022
Elevated 18:0 lysophosphatidylcholine contributes to the development of pain in tissue injury
Friston DA, Cuddihy J, Souza Luiz J, Truong AH, Ho L, Basra M, Santha P, Oszlacs O, de Sousa Valente J, Marczylo T, Junttila S, Laycock H, Collins D, Vizcaychipi M, Gyenesei A, Takats Z, Jancso G, Want E, Nagy I
PAIN 2022
The Role of the Skin in Interoception: A Neglected Organ?
Crucianelli L, Ehrsson HH
Perspectives on Psychological Science 2022
Genetic mechanisms modulating behaviour through plastic chemosensory responses in insects
Kohlmeier P, Billeter J
Molecular ecology 2022
Neuronal and non-neuronal TRPA1 as therapeutic targets for pain and headache relief
Iannone LF, Nassini R, Patacchini R, Geppetti P, De Logu F
2022
Neuropathic pain and chronic pain as an underestimated interdisciplinary problem.
Szewczyk AK, Jamroz-Wiśniewska A, Haratym N, Rejdak K
International Journal of Occupational Medicine and Environmental Health 2022
Transcriptional profiling of neuronal ion channels in dorsal root ganglion–derived immortal cell line (F-11) under different culture conditions
Morato EO, Knight B, Nair LS
2022
Co-Players in Chronic Pain: Neuroinflammation and the Tryptophan-Kynurenine Metabolic Pathway
M Tanaka, N Török, F Tóth, Á Szabó, L Vécsei
Biomedicines 2021
Made in Germany: A Quality Indicator Not Only in the Automobile Industry But Also When It Comes to Skin Replacement: How an Automobile Textile Research Institute Developed a New Skin Substitute
HL Haller, M Rapp, D Popp, SP Nischwitz, LP Kamolz
Medicina 2021
Pain Control by Targeting Oxidized Phospholipids: Functions, Mechanisms, Perspectives
B Oehler, A Brack, R Blum, HL Rittner
Frontiers in Endocrinology 2021
Properties and Differential Expression of H+ Receptors in Dorsal Root Ganglia: Is a Labeled-Line Coding for Acid Nociception Possible?
O Páez, P Segura-Chama, A Almanza, F Pellicer, F Mercado
Frontiers in physiology 2021
Sensory neuron–associated macrophages as novel modulators of neuropathic pain
CE Silva, RM Guimarães, TM Cunha
PAIN Reports 2021
Equine Cervical Pain and Dysfunction: Pathology, Diagnosis and Treatment
MR Story, KK Haussler, YS Nout-Lomas, TA Aboellail, CE Kawcak, MF Barrett, DD Frisbie, CW McIlwraith
Animals 2021
The role of intra-articular neuronal CCR2 receptors in knee joint pain associated with experimental osteoarthritis in mice
S Ishihara, AM Obeidat, DL Wokosin, D Ren, RJ Miller, AM Malfait, RE Miller
Arthritis Research & Therapy 2021
Piezo2 mechanosensitive ion channel is located to sensory neurons and nonneuronal cells in rat peripheral sensory pathway: implications in pain
SM Shin, F Moehring, B Itson-Zoske, F Fan, CL Stucky, QH Hogan, H Yu
PAIN 2021
RETRACTED: Noopept; a nootropic dipeptide, modulates persistent inflammation by effecting spinal microglia dependent Brain Derived Neurotropic Factor (BDNF) and pro-BDNF expression throughout apoptotic process
M Taghizadeh, N Maghsoudi, H Manaheji, V Akparov, M Baniasadi, M Mohammadi, S Danyali, R Ghasemi, J Zaringhalam
Heliyon 2021
γδ T Cells Participating in Nervous Systems: A Story of Jekyll and Hyde
Y Li, Y Zhang, X Zeng
Frontiers in immunology 2021
Studying human nociceptors: from fundamentals to clinic
SJ Middleton, AM Barry, M Comini, Y Li, PR Ray, S Shiers, AC Themistocleous, ML Uhelski, X Yang, PM Dougherty, TJ Price, DL Bennett
Brain 2021
Touch inhibits touch: sanshool-induced paradoxical tingling reveals perceptual interaction between somatosensory submodalities
A Cataldo, N Hagura, Y Hyder, P Haggard
Proceedings of the Royal Society B: Biological Sciences 2021
Inhibition of the Soluble Epoxide Hydrolase as an Analgesic Strategy: A Review of Preclinical Evidence
Y Wang, KM Wagner, C Morisseau, BD Hammock
Journal of pain research 2021
Sharpness recognition based on synergy between bio-inspired nociceptors and tactile mechanoreceptors
A Parvizi-Fard, N Salimi-Nezhad, M Amiri, E Falotico, C Laschi
Scientific Reports 2021
Optical Assessment of Nociceptive TRP Channel Function at the Peripheral Nerve Terminal
F Aleixandre-Carrera, N Engelmayer, D Ares-Suárez, M del Carmen Acosta, C Belmonte, J Gallar, V Meseguer, AM Binshtok
International journal of molecular sciences 2021
Scanned optogenetic control of mammalian somatosensory input to map input-specific behavioral outputs
A Schorscher-Petcu, F Takács, LE Browne
eLife 2021
Mechanisms of microbial–neuronal interactions in pain and nociception
VN Lagomarsino, AD Kostic, IM Chiu
Neurobiology of Pain 2021
Sex differences in neuroimmune and glial mechanisms of pain
AM Gregus, IS Levine, KA Eddinger, TL Yaksh, MW Buczynski
PAIN 2021
A ligand-receptor interactome platform for discovery of pain mechanisms and therapeutic targets
A Wangzhou, C Paige, SV Neerukonda, DK Naik, M Kume, ET David, G Dussor, PR Ray, TJ Price
Science signaling 2021
Predicting Individual Pain Thresholds From Morphological Connectivity Using Structural MRI: A Multivariate Analysis Study
R Zou, L Li, L Zhang, G Huang, Z Liang, Z Zhang
Frontiers in neuroscience 2021
Early Detection of Diabetic Peripheral Neuropathy: A Focus on Small Nerve Fibres
J Burgess, B Frank, A Marshall, RS Khalil, G Ponirakis, IN Petropoulos, DJ Cuthbertson, RA Malik, U Alam
Diagnostics 2021
In silico Identification of Key Factors Driving the Response of Muscle Sensory Neurons to Noxious Stimuli
S Nagaraja, LF Queme, MC Hofmann, SG Tewari, MP Jankowski, J Reifman
Frontiers in neuroscience 2021
HDAC6: A Key Link Between Mitochondria and Development of Peripheral Neuropathy
K English, MC Barton
Frontiers in molecular neuroscience 2021
Cryo-EM structures of human TMEM120A and TMEM120B
M Ke, Y Yu, C Zhao, S Lai, Q Su, W Yuan, L Yang, D Deng, K Wu, W Zeng, J Geng, J Wu, Z Yan
Cell Discovery 2021
Morphine-sensitive synaptic transmission emerges in embryonic rat microphysiological model of lower afferent nociceptive signaling
KJ Pollard, DA Bowser, WA Anderson, M Meselhe, MJ Moore
Science Advances 2021
The neuronal potassium current I A is a potential target for pain during chronic inflammation
M Biet, MA Dansereau, P Sarret, R Dumaine
Physiological Reports 2021
Pain Neuroscience Education Delivered by a Student Physical Therapist for a Patient with Persistent Musculoskeletal Pain
M OConnor, R Sillevis, MR Erickson
American Journal of Case Reports 2021
Suppression of Pain in the Late Phase of Chronic Trigeminal Neuropathic Pain Failed to Rescue the Decision-Making Deficits in Rats
SK Murugappan, L Xie, HY Wong, Z Iqbal, Z Lei, AS Ramkrishnan, Y Li
International journal of molecular sciences 2021
Intercellular Arc Signaling Regulates Vasodilation
JB de la Peña, P Barragan-Iglesias, TF Lou, N Kunder, S Loerch, T Shukla, L Basavarajappa, J Song, DN James, S Megat, JK Moy, A Wanghzou, PR Ray, K Hoyt, O Steward, TJ Price, J Shepherd, ZT Campbell
The Journal of neuroscience : the official journal of the Society for Neuroscience 2021
Sensory defunctionalization induced by 8% topical capsaicin treatment in a model of ultraviolet-B-induced cutaneous hyperalgesia
SL Vecchio, HH Andersen, J Elberling, L Arendt-Nielsen
Experimental Brain Research 2021
Multi-Electrode Array of Sensory Neurons as an In Vitro Platform to Identify the Nociceptive Response to Pharmaceutical Buffer Systems of Injectable Biologics
M Eaton, Z Que, J Zhang, K Beck, R Shi, J McDermott, M Ladisch, Y Yang
Pharmaceutical Research 2021
Analgesic effect of central relaxin receptor activation on persistent inflammatory pain in mice: behavioral and neurochemical data
C Abboud, L Brochoire, A Drouet, MA Hossain, W Hleihel, AL Gundlach, M Landry
PAIN Reports 2021
“I’ll Be Back”: The Resurrection of Dezocine
WE Childers, MA Abou-Gharbia
ACS Medicinal Chemistry Letters 2021
Intrinsic attention to pain is associated with a pronociceptive phenotype
G Adams, R Harrison, W Gandhi, CM van Reekum, TV Salomons
PAIN Reports 2021
Methylene Blue Application to Lessen Pain: Its Analgesic Effect and Mechanism
SW Lee, HC Han
Frontiers in neuroscience 2021
Pain in Oral and Maxillofacial Surgery and Implant Dentistry: Types and Management
DI Selvido, BP Bhattarai, D Rokaya, N Niyomtham, N Wongsirichat
European journal of dentistry 2021
The use of methadone in adult patients with cancer pain at a governmental cancer center in India
G Palat, C Algotsson, S Rayala, V Haridass, J Nethagani, M Ahmed, V Rapelli, MG Medhin, E Brun, M Segerlantz
Indian Journal of Palliative Care 2021
Bio‐Inspired Multi‐Mode Pain‐Perceptual System (MMPPS) with Noxious Stimuli Warning, Damage Localization, and Enhanced Damage Protection
F Li, S Gao, Y Lu, W Asghar, J Cao, C Hu, H Yang, Y Wu, S Li, J Shang, M Liao, Y Liu, RW Li
Advanced Science 2021
Novel Insights Into Rheumatoid Arthritis Through Characterization of Concordant Changes in DNA Methylation and Gene Expression in Synovial Biopsies of Patients With Differing Numbers of Swollen Joints
AY Yim, E Ferrero, K Maratou, HD Lewis, G Royal, DF Tough, C Larminie, MM Mannens, P Henneman, WJ de Jonge, MG van de Sande, DM Gerlag, RK Prinjha, PP Tak
Frontiers in immunology 2021
Acupuncture for blunt chest trauma: A protocol for a double-blind randomized control trial
PY Kao, E Ben-Arie, TY Lu, WC Ho, YC Lee, YS Lin, CK Chen, JX Chen, TM Huang, FP Chen
Medicine 2021
Healthy Intestinal Function Relies on Coordinated Enteric Nervous System, Immune System, and Epithelium Responses
FB Saldana-Morales, DV Kim, MT Tsai, GE Diehl
Gut microbes 2021
Patient-Specific Planning for Thermal Magnetic Resonance of Glioblastoma Multiforme
E Oberacker, C Diesch, J Nadobny, A Kuehne, P Wust, P Ghadjar, T Niendorf
Cancers 2021
The changes of nociception and the signal molecules expression in the dorsal root ganglia and the spinal cord after cold water swimming stress in mice
JH Feng, SM Sim, JS Park, JS Hong, HW Suh
The Korean Journal of Physiology & Pharmacology 2021
A digital nervous system aiming toward personalized IoT healthcare
A Armgarth, S Pantzare, P Arven, R Lassnig, H Jinno, EO Gabrielsson, Y Kifle, D Cherian, TA Sjöström, G Berthou, J Dowling, T Someya, JJ Wikner, G Gustafsson, DT Simon, M Berggren
Scientific Reports 2021
Effect of dural inflammatory soup application on activation and sensitization markers in the caudal trigeminal nucleus of the rat and the modulatory effects of sumatriptan and kynurenic acid
E Spekker, KF Laborc, Z Bohár, G Nagy-Grócz, A Fejes-Szabó, M Szűcs, L Vécsei, Á Párdutz
The Journal of Headache and Pain 2021
Diversity of Receptor Expression in Central and Peripheral Mouse Neurons Estimated from Single Cell RNA Sequencing
A Wangzhou, C Paige, PR Ray, G Dussor, TJ Price
Neuroscience 2021
Multi-Channel RF Supervision Module for Thermal Magnetic Resonance Based Cancer Therapy
H Han, E Oberacker, A Kuehne, S Wang, TW Eigentler, E Grass, T Niendorf
Cancers 2021
Mechanisms and Pathways of Pain Photobiomodulation: A Narrative Review
K Cheng, LF Martin, MJ Slepian, AM Patwardhan, MM Ibrahim
The journal of pain : official journal of the American Pain Society 2021
Changes in peripheral HCN2 channels during persistent inflammation
LA Jansen, LA Forster, XL Smith, M Rubaharan, AZ Murphy, DJ Baro
Channels (Austin, Tex.) 2021
Signaling via the FLP-14/FRPR-19 neuropeptide pathway sustains nociceptive response to repeated noxious stimuli in C. elegans
F Marques, L Falquet, E Vandewyer, I Beets, DA Glauser, K Ashrafi
PLoS genetics 2021
Ca2+/CaM binding to CaMKI promotes IMA-3 importin binding and nuclear translocation in sensory neurons to control behavioral adaptation
D Ippolito, S Thapliyal, DA Glauser
eLife 2021
Ion Channels in Biophysics and Physiology
L Zhou
2021
Characterization of Patients With and Without Painful Peripheral Neuropathy After Receiving Neurotoxic Chemotherapy: Traditional Quantitative Sensory Testing vs C-Fiber and Aδ-Fiber Selective Diode Laser Stimulation.
Nemenov MI, Alaverdyan H, Burk C, Roles K, Frey K, Yan Y, Kazinets G, Haroutounian S
The Journal of Pain 2021
Artificial Adaptive and Maladaptive Sensory Receptors Based on a Surface‐Dominated Diffusive Memristor
Song YG, Suh JM, Park JY, Kim JE, Chun SY, Kwon JU, Lee H, Jang HW, Kim S, Kang C, Yoon JH
Advanced Science 2021
From NSAIDs to Glucocorticoids and Beyond.
Sinniah A, Yazid S, Flower RJ
Cells 2021
Estrogen-dependent regulation of transient receptor potential vanilloid 1 (TRPV1) and P2X purinoceptor 3 (P2X3): Implication in burning mouth syndrome
Seol SH, Chung G
Journal of Dental Sciences 2021
Effective Ultrasonic Stimulation in Human Peripheral Nervous System.
Riis T, Kubanek J
IEEE transactions on bio-medical engineering 2021
Spinal integration of hot and cold nociceptive stimuli by wide-dynamic-range neurons in anesthetized adult rats
Gieré C, Melchior M, Dufour A, Poisbeau P
PAIN Reports 2021
Randomized cross-over evaluation of investigator gender on pain thresholds in healthy volunteers.
Sellgren Engskov A, Lejbman I, Åkeson J
German medical science : GMS e-journal 2021
Hematopoietic stem cell mobilization
Chang HH, Liou YS, Sun DS
2021
Perineural local anesthetic treatments for osteoarthritic pain
Knight B, Walker J, Nair LS
Regenerative Engineering and Translational Medicine 2021
Human Spinal Organoid-on-a-Chip to Model Nociceptive Circuitry for Pain Therapeutics Discovery.
Ao Z, Cai H, Wu Z, Krzesniak J, Tian C, Lai YY, Mackie K, Guo F
Analytical chemistry 2021
Sensory satellite glial Gq-GPCR activation alleviates inflammatory pain via peripheral adenosine 1 receptor activation
AX Xie, A Madayag, SK Minton, KD McCarthy, AP Malykhina
Scientific Reports 2020
Independent evolution of pain insensitivity in African mole-rats: origins and mechanisms
ES Smith, TJ Park, GR Lewin
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology 2020
Neural Regulation of Interactions Between Group 2 Innate Lymphoid Cells and Pulmonary Immune Cells
W Chen, Q Shu, J Fan
Frontiers in immunology 2020
T-cells produce acidic niches in lymph nodes to suppress their own effector functions
H Wu, V Estrella, M Beatty, D Abrahams, A El-Kenawi, S Russell, A Ibrahim-Hashim, DL Longo, YK Reshetnyak, A Moshnikova, OA Andreev, K Luddy, M Damaghi, K Kodumudi, SR Pillai, P Enriquez-Navas, S Pilon-Thomas, P Swietach, RJ Gillies
Nature Communications 2020
The “Culture” of Pain Control: A Review of Opioid-Induced Dysbiosis (OID) in Antinociceptive Tolerance
RA Mischel, KH Muchhala, WL Dewey, HI Akbarali
The journal of pain : official journal of the American Pain Society 2020
Electrical Stimulation of Cranial Nerves in Cognition and Disease
D Adair, D Truong, Z Esmaeilpour, N Gebodh, H Borges, L Ho, JD Bremner, BW Badran, V Napadow, VP Clark, M Bikson
Brain Stimulation 2020
Transient receptor potential vanilloid 4 channels as therapeutic targets in diabetes and diabetes‐related complications
W Hu, Y Ding, Q Li, R shi, Y He
Journal of Diabetes Investigation 2020
Neuro-Immune Circuits Regulate Immune Responses in Tissues and Organ Homeostasis
MO Jakob, S Murugan, CS Klose
Frontiers in immunology 2020
TRPA1 as a therapeutic target for nociceptive pain
DS de Araujo, R Nassini, P Geppetti, FD Logu
Expert Opinion on Therapeutic Targets 2020
Expression of huntingtin-associated protein 1 in adult mouse dorsal root ganglia and its neurochemical characterization in reference to sensory neuron subpopulations
N Islam, N Maeda, E Miyasato, MR Jahan, AM Tarif, T Ishino, K Nozaki, K Masumoto, A Yanai, K Shinoda
IBRO Reports 2020
Neural Immune Communication in the Control of Host-Bacterial Pathogen Interactions in the Gastrointestinal Tract
V Ramirez, S Swain, K Murray, C Reardon, AR Richardson
Infection and immunity 2020
A mini-review: Bridging the gap between autism spectrum disorder and pain comorbidities
CO Brown, J Uy, KK Singh
2020
Ocular Surface Pain: A Narrative Review
D Mehra, NK Cohen, A Galor
Ophthalmology and Therapy 2020
Taste the Pain: The Role of TRP Channels in Pain and Taste Perception
E Aroke, K Powell-Roach, R Jaime-Lara, M Tesfaye, A Roy, P Jackson, P Joseph
International journal of molecular sciences 2020
A Synoptic Overview of Neurovascular Interactions in the Foot
G Balasubramanian, P Vas, N Chockalingam, R Naemi
Frontiers in Endocrinology 2020
Ketamine normalizes high-gamma power in the anterior cingulate cortex in a rat chronic pain model
ID Friesner, E Martinez, H Zhou, JD Gould, A Li, ZS Chen, Q Zhang, J Wang
Molecular brain 2020
Bone marrow mesenchymal stem cell-derived exosomes protect cartilage damage and relieve knee osteoarthritis pain in a rat model of osteoarthritis
L He, T He, J Xing, Q Zhou, L Fan, C Liu, Y Chen, D Wu, Z Tian, B Liu, L Rong
Stem Cell Research & Therapy 2020
The Delta-Opioid Receptor; a Target for the Treatment of Pain
B Quirion, F Bergeron, V Blais, L Gendron
Frontiers in molecular neuroscience 2020
How Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) Progresses: The Natural History of ME/CFS
L Nacul, S O'Boyle, L Palla, FE Nacul, K Mudie, CC Kingdon, JM Cliff, TG Clark, HM Dockrell, EM Lacerda
Frontiers in neurology 2020
Differentiation of the 50B11 dorsal root ganglion cells into NGF and GDNF responsive nociceptor subtypes
M Dusan, C Jastrow, MM Alyce, W Yingkai, M Shashikanth, E Andelain, BM Christine, BM Stuart, BG Oliver, MZ Michael, VH Nicolas, KJ Damien, HV Rainer
Molecular Pain 2020
A mechanistic approach to HPLC analysis, antinociceptive, anti-inflammatory and postoperative analgesic activities of panch phoron in mice
ZT Gias, F Afsana, P Debnath, MS Alam, TN Ena, H Hossain, P Jain, HM Reza
2020
Trigeminal neuralgia: An overview from pathophysiology to pharmacological treatments
E Gambeta, JG Chichorro, GW Zamponi
Molecular Pain 2020
Critical biomechanical and clinical insights concerning tissue protection when positioning patients in the operating room: A scoping review
A Gefen, S Creehan, J Black
International Wound Journal 2020
Orofacial quantitative sensory testing: Current evidence and future perspectives
FV der Cruyssen, LV Tieghem, TM Croonenborghs, L BaadHansen, P Svensson, T Renton, R Jacobs, C Politis, AD Laat
European journal of pain (London, England) 2020
Analgesic dorsal root ganglionic field stimulation blocks conduction of afferent impulse trains selectively in nociceptive sensory afferents
D Chao, Z Zhang, CM Mecca, QH Hogan, B Pan
PAIN 2020
A pharmacological interactome between COVID-19 patient samples and human sensory neurons reveals potential drivers of neurogenic pulmonary dysfunction
PR Ray, A Wangzhou, N Ghneim, MS Yousuf, C Paige, D Tavares-Ferreira, JM Mwirigi, S Shiers, I Sankaranarayanan, AJ McFarland, SV Neerukonda, S Davidson, G Dussor, MD Burton, TJ Price
Brain, Behavior, and Immunity 2020
A Fatal Alliance between Microglia, Inflammasomes, and Central Pain
S Hoffmann, C Beyer
International journal of molecular sciences 2020
Selenium and Neurological Diseases: Focus on Peripheral Pain and TRP Channels
M Nazıroğlu, A Öz, K Yıldızhan
Current neuropharmacology 2020
A Pharmacological Interactome between COVID-19 Patient Samples and Human Sensory Neurons Reveals Potential Drivers of Neurogenic Pulmonary Dysfunction
P Ray, A Wangzhou, N Ghneim, M Yousuf, C Paige, D Tavares-Ferreira, J Mwirigi, S Shiers, I Sankaranarayanan, A Balmain, S Neerukonda, S Davidson, G Dussor, M Burton, T Price
SSRN Electronic Journal 2020
Granulocyte-Macrophage Colony Stimulating Factor As an Indirect Mediator of Nociceptor Activation and Pain
D Tewari, AD Cook, MC Lee, AD Christensen, A Croxford, B Becher, D Poole, P Rajasekhar, N Bunnett, JE Smith, JA Hamilton, SB McMahon
The Journal of neuroscience : the official journal of the Society for Neuroscience 2020
Targeted manipulation of pain neural networks: The potential of focused ultrasound for treatment of chronic pain
N Todd, N McDannold, D Borsook
Neuroscience and biobehavioral reviews 2020
Pain-sensing neurons mobilize blood stem cells from bone marrow
AN Tikhonova, I Aifantis
Nature 2020
Examining Sodium and Potassium Channel Conductances Involved in Hyperexcitability of Chemotherapy-Induced Peripheral Neuropathy: A Mathematical and Cell Culture-Based Study
P Verma, M Eaton, A Kienle, D Flockerzi, Y Yang, D Ramkrishna
Frontiers in Computational Neuroscience 2020
Genetics of pain: From rare Mendelian disorders to genetic predisposition to pain
Zakira Naureen, Lorenzo Lorusso, Paolo Manganotti, Paola Caruso, Giulia Mazzon, Stefano Cecchin, Giuseppe Marceddu, Matteo Bertelli
Acta bio-medica : Atenei Parmensis 2020
The Input-Output Relation of Primary Nociceptive Neurons is Determined by the Morphology of the Peripheral Nociceptive Terminals
O Barkai, R Butterman, B Katz, S Lev, AM Binshtok
The Journal of neuroscience : the official journal of the Society for Neuroscience 2020
Spinal astrocytes in superficial laminae gate brainstem descending control of mechanosensory hypersensitivity
Y Kohro, T Matsuda, K Yoshihara, K Kohno, K Koga, R Katsuragi, T Oka, R Tashima, S Muneta, T Yamane, S Okada, K Momokino, A Furusho, K Hamase, T Oti, H Sakamoto, K Hayashida, R Kobayashi, T Horii, I Hatada, H Tozaki-Saitoh, K Mikoshiba, V Taylor, K Inoue, M Tsuda
Nature Neuroscience 2020
Machine learning-based automated phenotyping of inflammatory nocifensive behavior in mice
JM Wotton, E Peterson, L Anderson, SA Murray, RE Braun, EJ Chesler, JK White, V Kumar
Molecular Pain 2020
Conditional Lpar1 gene targeting identifies cell types mediating neuropathic pain
RR Rivera, ME Lin, EC Bornhop, J Chun
The FASEB Journal 2020

Improvement of Pain and Function After Use of a Topical Pain Relieving Patch: Results of the RELIEF Study


JA Gudin, DT Dietze, PL Hurwitz
Journal of pain research 2020

Effect of Peritumoral Bupivacaine on Primary and Distal Hyperalgesia in Cancer-Induced Bone Pain


SE Mathew, P Madhusudanan, SA Shankarappa
Journal of pain research 2020
Functional Expression of Piezo1 in Dorsal Root Ganglion (DRG) Neurons
J Roh, SM Hwang, SH Lee, K Lee, YH Kim, CK Park
International journal of molecular sciences 2020
Resveratrol alleviates diabetic mechanical allodynia in rats by downregulating P2X3R
Y Cui, Y Li, J Ning, Y Mi, X Wang, Z Qiu, L Li, X Gou
Molecular medicine reports 2020
Alterations in SUMOylation of the hyperpolarization‐activated cyclic nucleotide‐gated ion channel 2 during persistent inflammation
LA Forster, LA Jansen, M Rubaharan, AZ Murphy, DJ Baro
European journal of pain (London, England) 2020
Selected pathobiological features and principles of pharmacological pain management
RA Khammissa, R Ballyram, J Fourie, M Bouckaert, J Lemmer, L Feller
J INT MED RES 2020
Coagulation factor XII contributes to hemostasis when activated by soil in wounds
LJ Juang, N Mazinani, SK Novakowski, EN Prowse, M Haulena, D Gailani, LM Lavkulich, CJ Kastrup
Blood Advances 2020
Dynamics of the perception and EEG signals triggered by tonic warm and cool stimulation
D Mulders, C de Bodt, N Lejeune, A Courtin, G Liberati, M Verleysen, A Mouraux, JR Buitenweg
PloS one 2020
Pharmacopuncture of Bauhinia variegata Nanoemulsion Formulation against Diabetic Peripheral Neuropathic Pain
Pushpraj S Gupta, Sunil K Singh, Abhishek K Tripathi
Journal of Pharmacopuncture 2020
A system for the high-throughput analysis of acute thermal avoidance and adaptation in C. elegans
AS Lia, DA Glauser
Journal of Biological Methods 2020
Role of mechanosensitive ion channels in the sensation of pain
R Sharif-Naeini
Journal of Neural Transmission 2020
Decoding of Pain Perception using EEG Signals for a Real-Time Reflex System in Prostheses: A Case Study
Z Tayeb, R Bose, A Dragomir, LE Osborn, NV Thakor, G Cheng
Scientific Reports 2020
Advances in the understanding and treatment of pain and headache
R Dallel
Journal of Neural Transmission 2020
Increasing Warmth in Adolescents with Anorexia Nervosa: A Randomized Controlled Crossover Trial Examining the Efficacy of Mustard and Ginger Footbaths
S Kuderer, E Helmert, H Szöke, S Joos, M Kohl, J Svaldi, F Beissner, F Andrasik, J Vagedes
Evidence-Based Complementary and Alternative Medicine 2020
Transcutaneous Electrical Nerve Stimulation in Relieving Neuropathic Pain: Basic Mechanisms and Clinical Applications
T Mokhtari, Q Ren, N Li, F Wang, Y Bi, L Hu
Current Pain and Headache Reports 2020
Adhesive dentistry sensory stimulus technique as a neuromechanism for the treatment of orofacial pain associated to temporomandibular disorders: Case study
MP Clemente, A Pinto, F Milheiro, TF Costa, A Moreira, R Vardasca, PA Pereira, J Mendes, MD Madeira, JM Amarante
Journal of Oral Biology and Craniofacial Research 2020
Contact Heat Evoked Potentials Are Responsive to Peripheral Sensitization: Requisite Stimulation Parameters
LD Linde, J Haefeli, CR Jutzeler, J Rosner, J McDougall, A Curt, JL Kramer
Frontiers in human neuroscience 2020
Pain-free resting-state functional brain connectivity predicts individual pain sensitivity
T Spisak, B Kincses, F Schlitt, M Zunhammer, T Schmidt-Wilcke, ZT Kincses, U Bingel
Nature Communications 2020
Spatial models of cell distribution in human lumbar dorsal root ganglia
ZJ Sperry, RD Graham, N PeckDimit, SF Lempka, TM Bruns
The Journal of Comparative Neurology 2020
Is TRPA1 Burning Down TRPV1 as Druggable Target for the Treatment of Chronic Pain?
S Giorgi, M Nikolaeva-Koleva, D Alarcón-Alarcón, L Butrón, S González-Rodríguez
International journal of molecular sciences 2019
Chronic Pain: Structural and Functional Changes in Brain Structures and Associated Negative Affective States
S Yang, MC Chang
International journal of molecular sciences 2019
Choreographing Immunity in the Skin Epithelial Barrier
T Kobayashi, S Naik, K Nagao
Immunity 2019
Oxidized Lipids in Persistent Pain States
T Osthues, M Sisignano
Frontiers in pharmacology 2019
Acupuncture-Analgesia-Mediated Alleviation of Central Sensitization
HC Lai, YW Lin, CL Hsieh
Evidence-Based Complementary and Alternative Medicine 2019
The Itch-Scratch Cycle: A Review of the Mechanisms
G Rinaldi
Dermatology Practical & Conceptual 2019
Capsaicin: Physicochemical properties, cutaneous reactions and potential applications in painful and inflammatory conditions (Review)
M Ilie, C Caruntu, M Tampa, SR Georgescu, C Matei, C Negrei, RM Ion, C Constantin, M Neagu, D Boda
Experimental and therapeutic medicine 2019
PIEZO1 Is Selectively Expressed in Small Diameter Mouse DRG Neurons Distinct From Neurons Strongly Expressing TRPV1
J Wang, JH La, OP Hamill
Frontiers in molecular neuroscience 2019
Antibacterial, anti-inflammatory and peroxidase-mediated cyclooxygenase-1 inhibitory properties of Fusarium solani extract
K Ngwoke, N Tochukwu, C Ekwealor, V Nwankwo, U Obi-Okafor, C Izundu, FB Okoye, C Esimone, P Proksch, C Situ
Pharmaceutical Biology 2019
A modified Hodgkin–Huxley model to show the effect of motor cortex stimulation on the trigeminal neuralgia network
M Khodashenas, G Baghdadi, F Towhidkhah
Journal of Mathematical Neuroscience 2019
Growth Factor Signaling Regulates Mechanical Nociception in Flies and Vertebrates
R Lopez-Bellido, S Puig, PJ Huang, CR Tsai, HN Turner, MJ Galko, HB Gutstein
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019
Spinal α 2 -adrenoceptors and neuropathic pain modulation; therapeutic target
Z Bahari, GH Meftahi
British Journal of Pharmacology 2019
MiR-1906 attenuates neuropathic pain in rats by regulating the TLR4/mTOR/ Akt signaling pathway
X Fang, H Zhou, S Huang, J Liu
Translational Neuroscience 2019
Bioinformatics Unmasks the Maneuverers of Pain Pathways in Acute Kidney Injury
A Gupta, S Puri, V Puri
Scientific Reports 2019
Hand-Feel Touch Cues and Their Influences on Consumer Perception and Behavior with Respect to Food Products: A Review
Pramudya, Seo
Foods 2019
Deep Sequencing of Somatosensory Neurons Reveals Molecular Determinants of Intrinsic Physiological Properties
Y Zheng, P Liu, L Bai, JS Trimmer, BP Bean, DD Ginty
Neuron 2019

A comparative experimental study of analgesic activity of a novel non-steroidal anti-inflammatory molecule – zaltoprofen, and a standard drug – piroxicam, using murine models


C Santenna, S Kumar, S Balakrishnan, R Jhaj, SN Ahmed
Journal of Experimental Pharmacology 2019
Tetrodotoxin-Sensitive Sodium Channels Mediate Action Potential Firing and Excitability in Menthol-Sensitive Vglut3-Lineage Sensory Neurons
TN Griffith, TA Docter, EA Lumpkin
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019
Differences between Dorsal Root and Trigeminal Ganglion Nociceptors in Mice Revealed by Translational Profiling
S Megat, PR Ray, D Tavares-Ferreira, JK Moy, I Sankaranarayanan, A Wanghzou, TF Lou, P Barragan-Iglesias, ZT Campbell, G Dussor, TJ Price
The Journal of neuroscience : the official journal of the Society for Neuroscience 2019
Loss of prostatic acid phosphatase and α-synuclein cause motor circuit degeneration without altering cerebellar patterning
M Rahimi-Balaei, M Buchok, P Vihko, FE Parkinson, H Marzban, L Chakrabarti
PloS one 2019
MNK-eIF4E signalling is a highly conserved mechanism for sensory neuron axonal plasticity: evidence from Aplysia californica
SM Mihail, A Wangzhou, KK Kunjilwar, JK Moy, G Dussor, ET Walters, TJ Price
Philosophical Transactions of the Royal Society B: Biological Sciences 2019
Could Mycolactone Inspire New Potent Analgesics? Perspectives and Pitfalls
ML Reynaert, D Dupoiron, E Yeramian, L Marsollier, P Brodin
Toxins 2019
Zebrafish oxytocin neurons drive nocifensive behavior via brainstem premotor targets
CL Wee, M Nikitchenko, WC Wang, SJ Luks-Morgan, E Song, JA Gagnon, O Randlett, IH Bianco, AM Lacoste, E Glushenkova, JP Barrios, AF Schier, S Kunes, F Engert, AD Douglass
Nature Neuroscience 2019
Electroacupuncture Relieves CCI-Induced Neuropathic Pain Involving Excitatory and Inhibitory Neurotransmitters
CP Huang, YW Lin, DY Lee, CL Hsieh
Evidence-Based Complementary and Alternative Medicine 2019
New Engineered-Botulinum Toxins Inhibit the Release of Pain-Related Mediators
M Tang, J Meng, J Wang
International journal of molecular sciences 2019
Thermal block of action potentials is primarily due to voltage-dependent potassium currents: a modeling study
M Ganguly, MW Jenkins, ED Jansen, HJ Chiel
Journal of Neural Engineering 2019
Peripheral Nociception Is Associated with Voluntary Activation Deficits and Quadriceps Weakness Following Total Knee Arthroplasty
BJ Loyd, SK Stackhouse, C Hogan, MR Dayton, JE Stevens-Lapsley, AJ Kittelson
The Journal of Bone and Joint Surgery. American volume. 2019
The Study of Pain in Rats and Mice
CM Larson, GL Wilcox, CA Fairbanks
Comparative medicine 2019
RNA control in pain: Blame it on the messenger
JB Peña, JJ Song, ZT Campbell
Wiley interdisciplinary reviews. RNA 2019
Pain in child patients: A review on managements
SM Dezfouli, S Khosravi
European Journal of Translational Myology 2019
The effects of kinesiology taping on experimentally-induced thermal and mechanical pain in otherwise pain-free healthy humans: A randomised controlled repeated-measures laboratory study
G Banerjee, M Briggs, MI Johnson, F Tremblay
PloS one 2019
Diabetic neuropathy
Feldman EL, Callaghan BC, Pop-Busui R, Zochodne DW, Wright DE, Bennett DL, Bril V, Russell JW, Viswanathan V
Nature Reviews Disease Primers 2019
Molecular and Functional Neuroscience in Immunity
VA Pavlov, SS Chavan, KJ Tracey
Annual Review of Immunology 2018
Alleviation of Trigeminal Nociception Using p75 Neurotrophin Receptor Targeted Lentiviral Interference Therapy
VB OLeary, M OConnell, I Antyborzec, V Ntziachristos, JO Dolly, SV Ovsepian
Neurotherapeutics 2018
Corneal pain and experimental model development
TB McKay, Y Seyed-Razavi, CE Ghezzi, G Dieckmann, TJ Nieland, DM Cairns, RE Pollard, P Hamrah, DL Kaplan
Progress in Retinal and Eye Research 2018
Nociceptor sensory neurons suppress neutrophil and γδ T cell responses in bacterial lung infections and lethal pneumonia
P Baral, BD Umans, L Li, A Wallrapp, M Bist, T Kirschbaum, Y Wei, Y Zhou, VK Kuchroo, PR Burkett, BG Yipp, SD Liberles, IM Chiu
Nature Medicine 2018
Staphylococcus aureus produces pain through pore-forming toxins and neuronal TRPV1 that is silenced by QX-314
KJ Blake, P Baral, T Voisin, A Lubkin, FA Pinho-Ribeiro, KL Adams, DP Roberson, YC Ma, M Otto, CJ Woolf, VJ Torres, IM Chiu
Nature Communications 2018
Sensing the heat with TRPM3
J Vriens, T Voets
Pflügers Archiv - European Journal of Physiology 2018
Accumulation of Cav3.2 T-type Calcium Channels in the Uninjured Sural Nerve Contributes to Neuropathic Pain in Rats with Spared Nerve Injury
W Chen, YN Chi, XJ Kang, QY Liu, HL Zhang, ZH Li, ZF Zhao, Y Yang, L Su, J Cai, FF Liao, M Yi, Y Wan, FY Liu
Frontiers in molecular neuroscience 2018
Oxytocin produces thermal analgesia via vasopressin-1a receptor by modulating TRPV1 and potassium conductance in the dorsal root ganglion neurons
RT Han, HB Kim, YB Kim, K Choi, GY Park, PR Lee, JH Lee, H Kim, CK Park, Y Kang, SB Oh, HS Na
The Korean Journal of Physiology & Pharmacology 2018
Plant-Based Cannabinoids for the Treatment of Chronic Neuropathic Pain
S Casey, C Vaughan
Medicines 2018
Prosthesis with neuromorphic multilayered e-dermis perceives touch and pain
LE Osborn, A Dragomir, JL Betthauser, CL Hunt, HH Nguyen, RR Kaliki, NV Thakor
2018
General Pathways of Pain Sensation and the Major Neurotransmitters Involved in Pain Regulation
M Yam, Y Loh, C Tan, SK Adam, NA Manan, R Basir
International journal of molecular sciences 2018
Effects of palonosetron for prophylaxis of postoperative nausea and vomiting in high-risk patients undergoing total knee arthroplasty: A prospective, randomized, double-blind, placebo-controlled study
JH Ryu, YT Jeon, B Min, JY Hwang, HM Sohn, SW Wesmiller
PloS one 2018
NaV1.9 Potentiates Oxidized Phospholipid-Induced TRP Responses Only under Inflammatory Conditions
C Martin, C Stoffer, M Mohammadi, J Hugo, E Leipold, B Oehler, HL Rittner, R Blum
Frontiers in molecular neuroscience 2018
Schwann Cell Responses and Plasticity in Different Dental Pulp Scenarios
E Couve, O Schmachtenberg
Frontiers in cellular neuroscience 2018
An artificial nociceptor based on a diffusive memristor
JH Yoon, Z Wang, KM Kim, H Wu, V Ravichandran, Q Xia, CS Hwang, JJ Yang
Nature Communications 2018
A bright future? Optogenetics in the periphery for pain research and therapy:
AD Mickle, RW Gereau
PAIN 2018
Acid-sensing ion channels: dual function proteins for chemo-sensing and mechano-sensing
YR Cheng, BY Jiang, CC Chen
Journal of Biomedical Science 2018
Crude extract and fractions from Eugenia uniflora Linn leaves showed anti-inflammatory, antioxidant, and antibacterial activities
TR Falcão, AA de Araújo, LA Soares, RT de Moraes Ramos, IC Bezerra, MR Ferreira, MA de Souza Neto, MC Melo, RF de Araújo, AC de Aguiar Guerra, JS de Medeiros, GC Guerra
BMC complementary and alternative medicine 2018
Effectiveness of cooling therapy (cryotherapy) on leg pain and self-efficacy in patients with chronic venous disease: A randomized controlled trial
TJ Kelechi, M Mueller, M Madisetti, MA Prentice, MJ Dooley
International Journal of Nursing Studies 2018
A-Type KV Channels in Dorsal Root Ganglion Neurons: Diversity, Function, and Dysfunction
BM Zemel, DM Ritter, M Covarrubias, T Muqeem
Frontiers in molecular neuroscience 2018
The time course of brief and prolonged topical 8% capsaicin-induced desensitization in healthy volunteers evaluated by quantitative sensory testing and vasomotor imaging
SL Vecchio, HH Andersen, L Arendt-Nielsen
Experimental Brain Research 2018
Antinociceptive Effects of the Antidepressant Phenelzine are Mediated by Context-Dependent Inhibition of Neuronal Responses in the Dorsal Horn
LE Potter, S Doolen, K Mifflin, G Tenorio, G Baker, BK Taylor, BJ Kerr
Neuroscience 2018
Augmenting the antinociceptive effects of nicotinic acetylcholine receptor activity through lynx1 modulation
NI Nissen, KR Anderson, H Wang, HS Lee, C Garrison, SA Eichelberger, K Ackerman, W Im, JM Miwa, I Silman
PloS one 2018
Analgesic properties of Nigella Sativa and Eucheuma Cottonii extracts
A Zakaria, MR Jais, R Ishak
Journal of Natural Science, Biology, and Medicine 2018
The Drosophila Small Conductance Calcium-Activated Potassium Channel Negatively Regulates Nociception
KC Walcott, SE Mauthner, A Tsubouchi, J Robertson, WD Tracey
Cell Reports 2018
Human vs. Mouse Nociceptors – Similarities and Differences
C Rostock, K Schrenk-Siemens, J Pohle, J Siemens
Neuroscience 2018
The mechanosensitive ion channel Piezo2 mediates sensitivity to mechanical pain in mice
SE Murthy, MC Loud, I Daou, KL Marshall, F Schwaller, J Kühnemund, AG Francisco, WT Keenan, AE Dubin, GR Lewin, A Patapoutian
Science Translational Medicine 2018
Immediate effect of application of the pressure technique to the psoas major on lumbar lordosis
T Otsudo, K Mimura, K Akasaka
Journal of Physical Therapy Science 2018
Targeted Mutation (R100W) of the Gene Encoding NGF Leads to Deficits in the Peripheral Sensory Nervous System
W Yang, K Sung, F Zhou, W Xu, RA Rissman, J Ding, C Wu
Frontiers in aging neuroscience 2018
Neonatal Pain
M Perry, Z Tan, J Chen, T Weidig, W Xu, XS Cong
Critical Care Nursing Clinics of North America 2018
Lysophosphatidic Acid and Ion Channels as Molecular Mediators of Pain
R Juárez-Contreras, T Rosenbaum, SL Morales-Lázaro
Frontiers in molecular neuroscience 2018
Neuropathic pain models and outcome measures: a dual translational challenge
RD Sewell
Annals of translational medicine 2018
Lamina-specific population encoding of cutaneous signals in the spinal dorsal horn using multi-electrode arrays: Linear multi-electrode arrays in the spinal dorsal horn
CM Greenspon, EE Battell, IM Devonshire, LF Donaldson, V Chapman, GJ Hathway
The Journal of Physiology 2018
In Situ Hybridisation Study of Neuronal Neuropeptides Expression in Models of Mandibular Denervation with or without Inflammation: Injury Dependant Neuropeptide Plasticity
SA El-Aleem, BM Morales-Aza
Journal of Cytology & Histology 2018
Mechanisms and Therapeutic Relevance of Neuro-immune Communication
SS Chavan, VA Pavlov, KJ Tracey
Immunity 2017
Pharmacological Regulation of Neuropathic Pain Driven by Inflammatory Macrophages
N Kiguchi, D Kobayashi, F Saika, S Matsuzaki, S Kishioka
International journal of molecular sciences 2017
Intravenous Lidocaine: Old-School Drug, New Purpose—Reduction of Intractable Pain in Patients with Chemotherapy Induced Peripheral Neuropathy
SA van Heuvel, SE van der Wal, LA Smedes, SA Radema, N Alfen, KC Vissers, MA Steegers
Pain Research & Management : The Journal of the Canadian Pain Society 2017
Increased spatial dimensions of repetitive heat and cold stimuli in older women:
KM Naugle, Y Cruz-Almeida, RB Fillingim, R Staud, JL Riley
PAIN 2017
Pain in ankylosing spondylitis: a neuro-immune collaboration
K Bidad, E Gracey, KS Hemington, JC Mapplebeck, KD Davis, RD Inman
Nature Reviews Rheumatology 2017
Sensory integration and neuromodulatory feedback facilitate Drosophila mechanonociceptive behavior
C Hu, M Petersen, N Hoyer, B Spitzweck, F Tenedini, D Wang, A Gruschka, LS Burchardt, E Szpotowicz, M Schweizer, AR Guntur, CH Yang, P Soba
Nature Neuroscience 2017
Effect of CXCL12/CXCR4 signaling on neuropathic pain after chronic compression of dorsal root ganglion
Y Yu, X Huang, Y Di, L Qu, N Fan
Scientific Reports 2017
Molecular Mechanisms That Contribute to Bone Marrow Pain
JJ Ivanusic
Frontiers in neurology 2017
Post-discharge hyperpolarization is an endogenous modulatory factor limiting input from fast-conducting nociceptors (AHTMRs)
MD Boada, DG Ririe, JC Eisenach
Molecular Pain 2017
The Molecular Fingerprint of Dorsal Root and Trigeminal Ganglion Neurons
DM Lopes, F Denk, SB McMahon
Frontiers in molecular neuroscience 2017
Looking beyond the intervertebral disc: the need for behavioral assays in models of discogenic pain: Behavioral assays in models of discogenic pain
GE Mosley, TW Evashwick-Rogler, A Lai, JC Iatridis
Annals of the New York Academy of Sciences 2017
Methods Used to Evaluate Pain Behaviors in Rodents
JR Deuis, LS Dvorakova, I Vetter
Frontiers in molecular neuroscience 2017
µ-Conotoxins Modulating Sodium Currents in Pain Perception and Transmission: A Therapeutic Potential
E Tosti, R Boni, A Gallo
Marine drugs 2017
Advances in understanding nociception and neuropathic pain
ES Smith
Journal of Neurology 2017
Calcineurin Dysregulation Underlies Spinal Cord Injury-Induced K + Channel Dysfunction in DRG Neurons
BM Zemel, T Muqeem, EV Brown, M Goulão, MW Urban, SR Tymanskyj, AC Lepore, M Covarrubias
The Journal of neuroscience : the official journal of the Society for Neuroscience 2017
Heat pain detection threshold is associated with the area of secondary hyperalgesia following brief thermal sensitization: a study of healthy male volunteers
MS Hansen, J Wetterslev, CB Pipper, MS Asghar, JB Dahl
Journal of pain research 2017
Animal Toxins Providing Insights into TRPV1 Activation Mechanism
M Geron, A Hazan, A Priel
Toxins 2017
Localized neuropathic pain: an expert consensus on local treatments
G PICKERING, E MARTIN, F Tiberghien, C Delorme, G Mick
Drug design, development and therapy 2017
Towards a neurobiological understanding of pain in chronic pancreatitis: mechanisms and implications for treatment
SS Olesen, T Krauss, IE Demir, OH Wilder-Smith, GO Ceyhan, PJ Pasricha, AM Drewes
PAIN Reports 2017
Adeno-associated virus serotype rh10 is a useful gene transfer vector for sensory nerves that innervate bone in immunodeficient mice
SH Park, MR Eber, S Tsuzuki, ME Booker, AG Sunil, DB Widner, RA Parker, CM Peters, Y Shiozawa
Scientific Reports 2017
Functional and Molecular Characterization of Mechanoinsensitive “Silent” Nociceptors
V Prato, FJ Taberner, JR Hockley, G Callejo, A Arcourt, B Tazir, L Hammer, P Schad, PA Heppenstall, ES Smith, SG Lechner
Cell Reports 2017
Secreted Phospholipases A2 from Animal Venoms in Pain and Analgesia
V Zambelli, G Picolo, C Fernandes, M Fontes, Y Cury
Toxins 2017
Characterization of Membrane Patch‐Ion Channel Probes for Scanning Ion Conductance Microscopy
W Shi, Y Zeng, C Zhu, Y Xiao, TR Cummins, J Hou, LA Baker
Small (Weinheim an Der Bergstrasse, Germany) 2017
Transcriptomic analyses of genes and tissues in inherited sensory neuropathies
MR Sapio, SC Goswami, JR Gross, AJ Mannes, MJ Iadarola
Experimental Neurology 2016
Aromatase inhibitors augment nociceptive behaviors in rats and enhance the excitability of sensory neurons
JD Robarge, DB Duarte, B Shariati, R Wang, DA Flockhart, MR Vasko
Experimental Neurology 2016
Distinct roles of exogenous opioid agonists and endogenous opioid peptides in the peripheral control of neuropathy-triggered heat pain
D Labuz, MÖ Celik, A Zimmer, H Machelska
Scientific Reports 2016
Pituitary adenylate cyclase-activating polypeptide expression in peripheral blood mononuclear cells of migraineurs
L Hou, D Wan, Z Dong, W Tang, X Han, L Li, F Yang, S Yu
Cell & Bioscience 2016
Role of Kv4.3 in Vibration-Induced Muscle Pain in the Rat
LB Conner, P Alvarez, O Bogen, JD Levine
The Journal of Pain 2016
Passiflora incarnata attenuation of neuropathic allodynia and vulvodynia apropos GABA-ergic and opioidergic antinociceptive and behavioural mechanisms
U Aman, F Subhan, M Shahid, S Akbar, N Ahmad, G Ali, K Fawad, RD Sewell
BMC complementary and alternative medicine 2016
Heat is absolute, cold is relative
I Vandewauw, T Voets
Nature Neuroscience 2016
Light-Emitting Diode Phototherapy Reduces Nocifensive Behavior Induced by Thermal and Chemical Noxious Stimuli in Mice: Evidence for the Involvement of Capsaicin-Sensitive Central Afferent Fibers
GR Pigatto, IS Coelho, RS Aquino, LF Bauermann, AR Santos
Molecular Neurobiology 2016
Distinct BOLD fMRI Responses of Capsaicin-Induced Thermal Sensation Reveal Pain-Related Brain Activation in Nonhuman Primates
AB Asad, S Seah, R Baumgartner, D Feng, A Jensen, E Manigbas, B Henry, A Houghton, JL Evelhoch, SW Derbyshire, CL Chin, AJ Schwarz
PloS one 2016
Peripheral nerve injury induces loss of nociceptive neuron-specific G i-interacting protein in neuropathic pain rat
Z Liu, F Wang, G Fischer, QH Hogan, H Yu
Molecular Pain 2016
Tyrosine Residue in the TRPV1 Vanilloid Binding Pocket Regulates Deactivation Kinetics
R Kumar, A Hazan, A Basu, N Zalcman, H Matzner, A Priel
The Journal of biological chemistry 2016
Analgesic effects of Chinese Tuina massage in a rat model of pain
S Jiang, H Zhang, M Fang, Y Zhang, N Lu, Q Zhu, Y Cheng, J Ai, N Zhou, J Li, L Fang, F Yao
Experimental and therapeutic medicine 2016
Characterization of cutaneous and articular sensory neurons
IS Serra, Z Husson, JD Bartlett, ES Smith
Molecular Pain 2016
Clinical features for diagnosis and management of patients with PRDM12 congenital insensitivity to pain
S Zhang, SM Sharif, YC Chen, EM Valente, M Ahmed, E Sheridan, C Bennett, G Woods
Journal of medical genetics 2016
Transcriptome Analysis of Chemically-Induced Sensory Neuron Ablation in Zebrafish
JA Cox, B Zhang, HM Pope, MM Voigt, S Allodi
PloS one 2016
Thermal referral: evidence for a thermoceptive uniformity illusion without touch
A Cataldo, ER Ferrè, G Pellegrino, P Haggard
Scientific Reports 2016
Exploring the Mechanisms of Exercise-Induced Hypoalgesia Using Somatosensory and Laser Evoked Potentials
MD Jones, JL Taylor, J Booth, BK Barry
Frontiers in physiology 2016
Cardioprotection by remote ischemic conditioning and its signal transduction
P Kleinbongard, A Skyschally, G Heusch
Pflügers Archiv - European Journal of Physiology 2016
A Comprehensive Functional Analysis of NTRK1 Missense Mutations Causing Hereditary Sensory and Autonomic Neuropathy Type IV (HSAN IV): HUMAN MUTATION
SS Shaikh, YC Chen, SA Halsall, MS Nahorski, K Omoto, GT Young, A Phelan, CG Woods
Human Mutation 2016
Mechanisms of low back pain: a guide for diagnosis and therapy
Allegri M, Montella S, Salici F, Valente A, Marchesini M, Compagnone C, Baciarello M, Manferdini ME, Fanelli G
F1000Research 2016
Post-translational modifications of voltage-gated sodium channels in chronic pain syndromes
CJ Laedermann, H Abriel, I Decosterd
Frontiers in pharmacology 2015
Neuroinflammation and Virus Replication in the Spinal Cord of Simian Immunodeficiency Virus–Infected Macaques:
LM Mangus, JL Dorsey, VA Laast, P Hauer, SE Queen, RJ Adams, JC McArthur, JL Mankowski
Journal of Neuropathology and Experimental Neurology 2015
Activity and Ca 2+ regulate the mobility of TRPV1 channels in the plasma membrane of sensory neurons: ( A ) Images of immobile sparklet (white circle) in dorsal root ganglion cell at time points when inactive (1) and active (2) with corresponding intensity trace below (see Video 1). ( B ) Moving sparklet recorded for 5.6 s in dorsal root ganglion cell (see Video 2). Inset is of sparklet trace magnified fivefold. Inset scale bar is 1 µm. All other scale bars are 5 µm. ( C ) Mean fluorescence intensity ( ΔF¯/F0 ) and ( D ) open probability (P open ) of dorsal root ganglion sparklets (N = 5; 3 cells) in Figure 1—figure supplement 1 A–E. Cut-off for ‘open’ is when intensity (ΔF/F 0 ) exceeds 0.05
EN Senning, SE Gordon
eLife 2015
Dysregulation of Kv3.4 Channels in Dorsal Root Ganglia Following Spinal Cord Injury
DM Ritter, BM Zemel, TJ Hala, ME O'Leary, AC Lepore, M Covarrubias
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015
Vertebrate Epidermal Cells Are Broad-Specificity Phagocytes That Clear Sensory Axon Debris
JP Rasmussen, GS Sack, SM Martin, A Sagasti
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015
Transcriptional regulator PRDM12 is essential for human pain perception
YC Chen, M Auer-Grumbach, S Matsukawa, M Zitzelsberger, AC Themistocleous, TM Strom, C Samara, AW Moore, LT Cho, GT Young, C Weiss, M Schabhüttl, R Stucka, AB Schmid, Y Parman, L Graul-Neumann, W Heinritz, E Passarge, RM Watson, JM Hertz, U Moog, M Baumgartner, EM Valente, D Pereira, CM Restrepo, I Katona, M Dusl, C Stendel, T Wieland, F Stafford, F Reimann, K Au, C Finke, PJ Willems, MS Nahorski, SS Shaikh, OP Carvalho, AK Nicholas, G Karbani, MA McAleer, MR Cilio, JC McHugh, SM Murphy, AD Irvine, UB Jensen, R Windhager, J Weis, C Bergmann, B Rautenstrauss, J Baets, PD Jonghe, MM Reilly, R Kropatsch, I Kurth, R Chrast, T Michiue, DL Bennett, CG Woods, J Senderek
Nature Genetics 2015
Cold shock induces apoptosis of dorsal root ganglion neurons plated on infrared windows
E Aboualizadeh, EC Mattson, CL O'Hara, AK Smith, CL Stucky, CJ Hirschmugl
The Analyst 2015
The pain receptor TRPV1 displays agonist-dependent activation stoichiometry
A Hazan, R Kumar, H Matzner, A Priel
Scientific Reports 2015
Neuropathic Pain due to Small Fiber Neuropathy in Aging: Current Management and Future Prospects
BA Brouwer, BT de Greef, JG Hoeijmakers, M Geerts, M Kleef, IS Merkies, CG Faber
Drugs & Aging 2015
Effects of dextromethorphan and oxycodone on treatment of neuropathic pain in mice
PP Yang, GC Yeh, EY Huang, PY Law, HH Loh, PL Tao
Journal of Biomedical Science 2015
TRP channel functions in the gastrointestinal tract
Xiaoyun Yu, Mingran Yu, Yingzhe Liu, Shaoyong Yu
Seminars in Immunopathology 2015
Inhibition of Inactive States of Tetrodotoxin-Sensitive Sodium Channels Reduces Spontaneous Firing of C-Fiber Nociceptors and Produces Analgesia in Formalin and Complete Freund’s Adjuvant Models of Pain
DJ Matson, DT Hamamoto, H Bregman, M Cooke, EF DiMauro, L Huang, D Johnson, X Li, J McDermott, C Morgan, B Wilenkin, AB Malmberg, SI McDonough, DA Simone, Z Zhang
PloS one 2015
Spike propagation through the dorsal root ganglia in an unmyelinated sensory neuron: a modeling study
D Sundt, N Gamper, DB Jaffe
Journal of neurophysiology 2015
Botulinum toxin-a treatment reduces human mechanical pain sensitivity and mechanotransduction: BoNT-A and Pain Sensitivity
K Paterson, S Lolignier, JN Wood, SB McMahon, DL Bennett
Annals of Neurology 2014
Acupuncture for Visceral Pain: Neural Substrates and Potential Mechanisms
S Chen, S Wang, P Rong, J Wang, L Qiao, X Feng, J Liu, J Zhang
Evidence-Based Complementary and Alternative Medicine 2014
LE135, a retinoid acid receptor antagonist, produces pain through direct activation of TRP channels: LE135 is an activator of TRPA1 and TRPV1
S Yin, J Luo, A Qian, W Yu, H Hu
British Journal of Pharmacology 2014
Sigma-1 receptor inhibition reverses acute inflammatory hyperalgesia in mice: role of peripheral sigma-1 receptors
MA Tejada, A Montilla-García, C Sánchez-Fernández, JM Entrena, G Perazzoli, JM Baeyens, EJ Cobos
Psychopharmacology 2014
ROS-mediated activation of Drosophila larval nociceptor neurons by UVC irradiation
MJ Kim, WA Johnson
BMC neuroscience 2014
Virally mediated optogenetic excitation and inhibition of pain in freely moving nontransgenic mice
SM Iyer, KL Montgomery, C Towne, SY Lee, C Ramakrishnan, K Deisseroth, SL Delp
Nature Biotechnology 2014
Stem Cells of the Apical Papilla Regulate Trigeminal Neurite Outgrowth and Targeting through a BDNF-Dependent Mechanism
JF de Almeida, P Chen, MA Henry, A Diogenes
Tissue Engineering Part A 2014
Deletion of interleukin-6 signal transducer gp130 in small sensory neurons attenuates mechanonociception and down-regulates TRPA1 expression
P Malsch, M Andratsch, C Vogl, AS Link, C Alzheimer, SM Brierley, PA Hughes, M Kress
The Journal of neuroscience : the official journal of the Society for Neuroscience 2014
Vitamin D: Recent Advances and Implications for Athletes
JJ Todd, LK Pourshahidi, EM McSorley, SM Madigan, PJ Magee
Sports Medicine 2014
Transcriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity: ( A ) SNS-Cre/TdTomato and Parv-Cre/TdTomato lumbar DRG sections imaged for TdTomato (red), IB4-FITC, anti-CGRP, or anti-Parvalbumin (green). Scale bars, 50 μm. ( B – C ) Proportions of IB4 + , CGRP + , NF200 + , Parvalbumin + populations expressing SNS-Cre/TdTomato or Parv-Cre/TdTomato, and converse TdTomato proportions expressing each co-stained marker (mean ± s.e.m., n = 8–20 fields from 3 animals). ( D ) Venn diagram depicting distinct DRG populations as labeled by Isolectin B4, NF200, and TdTomato populations. ( E ) For transcriptional profiling, three non-overlapping DRG populations were FACS purified: IB4 + SNS-Cre/TdTomato + , IB4 − SNS-Cre/TdTomato + , and Parv-Cre/TdTomato + cells
IM Chiu, LB Barrett, EK Williams, DE Strochlic, S Lee, AD Weyer, S Lou, GS Bryman, DP Roberson, N Ghasemlou, C Piccoli, E Ahat, V Wang, EJ Cobos, CL Stucky, Q Ma, SD Liberles, CJ Woolf
eLife 2014
Pain Related Channels Are Differentially Expressed in Neuronal and Non-Neuronal Cells of Glabrous Skin of Fabry Knockout Male Mice
J Lakomá, R Rimondini, V Donadio, R Liguori, M Caprini, JC Glorioso
PloS one 2014
Chemical Structure and Morphology of Dorsal Root Ganglion Neurons from Naive and Inflamed Mice
ME Barabas, EC Mattson, E Aboualizadeh, CJ Hirschmugl, CL Stucky
The Journal of biological chemistry 2014
The role of slow and persistent TTX-resistant sodium currents in acute tumor necrosis factor-α-mediated increase in nociceptors excitability
S Gudes, O Barkai, Y Caspi, B Katz, S Lev, AM Binshtok
Journal of neurophysiology 2014
Pain in cancer survivors
MR Brown, JD Ramirez, P Farquhar-Smith
British Journal of Pain 2014
Direct intrawound administration of dimethylsulphoxide relieves acute pain in rats: DMSO relieves pain
M Gautam, P Prasoon, R Kumar, A Singh, P Shrimal, SB Ray
International Wound Journal 2014
Wound infiltration with local anaesthetic agents for laparoscopic cholecystectomy
Loizides S, Gurusamy KS, Nagendran M, Rossi M, Guerrini GP, Davidson BR
The Cochrane Database of Systematic Reviews 2014
Targeting Pain-evoking Transient Receptor Potential Channels for the Treatment of Pain
J Luo, ET Walters, SM Carlton, H Hu
Current neuropharmacology 2013
The fundamental unit of pain is the cell
DB Reichling, PG Green, JD Levine
PAIN 2013
Pressure pain perception in the diabetic Charcot foot: facts and hypotheses
EA Chantelau, T Wienemann
Diabetic Foot & Ankle 2013
Neural processing of itch
T Akiyama, E Carstens
Neuroscience 2013
The role of corneal afferent neurons in regulating tears under normal and dry eye conditions
ID Meng, M Kurose
Experimental Eye Research 2013
Structure and function of hainantoxin-III, a selective antagonist of neuronal tetrodotoxin-sensitive voltage-gated sodium channels isolated from the Chinese bird spider Ornithoctonus hainana
Z Liu, T Cai, Q Zhu, M Deng, J Li, X Zhou, F Zhang, D Li, J Li, Y Liu, W Hu, S Liang
The Journal of biological chemistry 2013
Remote Optogenetic Activation and Sensitization of Pain Pathways in Freely Moving Mice
I Daou, AH Tuttle, G Longo, JS Wieskopf, RP Bonin, AR Ase, JN Wood, YD Koninck, A Ribeiro-da-Silva, JS Mogil, P Seguela
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013
The perception and endogenous modulation of pain
MH Ossipov
Scientifica 2012
Coordinate development of skin cells and cutaneous sensory axons in zebrafish
GS O'Brien, S Rieger, F Wang, GA Smolen, RE Gonzalez, JA Buchanan, A Sagasti
The Journal of Comparative Neurology 2012
Unraveling the mystery of pain in chronic pancreatitis
PJ Pasricha
Nature Reviews Gastroenterology & Hepatology 2012
Rise of the Sensors: Nociception and Pruritus
JN Baraniuk
Current Allergy and Asthma Reports 2012
Drosophila Nociceptors Mediate Larval Aversion to Dry Surface Environments Utilizing Both the Painless TRP Channel and the DEG/ENaC Subunit, PPK1
WA Johnson, JW Carder
PloS one 2012
Specific Paucity of Unmyelinated C-Fibers in Cutaneous Peripheral Nerves of the African Naked-Mole Rat: Comparative Analysis Using Six Species of Bathyergidae
ES Smith, B Purfürst, T Grigoryan, TJ Park, NC Bennett, GR Lewin
The Journal of Comparative Neurology 2012
Change in Prostaglandin Expression Levels and Synthesizing Activities in Dry Eye Disease
J Shim, C Park, HS Lee, MS Park, HT Lim, S Chauhan, R Dana, H Lee, HK Lee
Ophthalmology 2012
Activation of endogenous opioid gene expression in human keratinocytes and fibroblasts by pulsed radiofrequency energy fields
J Moffett, LM Fray, NJ Kubat
Journal of pain research 2012
Perception of thermal pain and the thermal grill illusion is associated with polymorphisms in the serotonin transporter gene
F Lindstedt, TB Lonsdorf, M Schalling, E Kosek, M Ingvar
PloS one 2011
What is this thing called pain?
CJ Woolf
Journal of Clinical Investigation 2010
Functional neurokinin and NMDA receptor activity in an animal naturally lacking substance P: the naked mole-rat
A Brand, ES Smith, GR Lewin, TJ Park
PloS one 2010
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009

← Previous 1 2 … 16 17 18 19 20 Next →

Advertisement

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts

Picked up by 104 news outlets
Blogged by 12
Posted by 43 X users
Referenced in 9 patents
On 8 Facebook pages
Referenced in 4 Wikipedia pages
Mentioned in 1 Q&A threads
On 6 videos
2744 readers on Mendeley
2 readers on CiteULike
See more details