Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • Vascular Malformations (Apr 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact

Citations to this article

A look at autoimmunity and inflammation in the eye
Rachel R. Caspi
Rachel R. Caspi
Published September 1, 2010
Citation Information: J Clin Invest. 2010;120(9):3073-3083. https://doi.org/10.1172/JCI42440.
View: Text | PDF
Review Article has an altmetric score of 14

A look at autoimmunity and inflammation in the eye

  • Text
  • PDF
Abstract

Autoimmune and inflammatory uveitis are a group of potentially blinding intraocular inflammatory diseases that arise without a known infectious trigger and are often associated with immunological responses to unique retinal proteins. In the United States, about 10% of the cases of severe visual handicap are attributed to this group of disorders. As I discuss here, experimental models of ocular autoimmunity targeting retinal proteins have brought about a better understanding of the basic immunological mechanisms involved in the pathogenesis of uveitis and are serving as templates for the development of novel therapies.

Authors

Rachel R. Caspi

×

Total citations by year

Year: 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Total
Citations: 12 17 13 26 28 16 18 14 12 17 21 13 12 13 12 1 1 246
Citation information
This citation data is accumulated from CrossRef, which receives citation information from participating publishers, including this journal. Not all publishers participate in CrossRef, so this information is not comprehensive. Additionally, data may not reflect the most current citations to this article, and the data may differ from citation information available from other sources (for example, Google Scholar, Web of Science, and Scopus).

Citations to this article in year 2014 (13)

Title and authors Publication Year
Immunotherapeutic strategies in autoimmune uveitis
PH Papotto, EB Marengo, LR Sardinha, AC Goldberg, LV Rizzo
Autoimmunity Reviews 2014
Lymphopenia-induced proliferation in aire-deficient mice helps to explain their autoimmunity and differences from human patients
K Kisand, P Peterson, M Laan
Frontiers in immunology 2014
Interleukin-35 induces regulatory B cells that suppress autoimmune disease
RX Wang, CR Yu, IM Dambuza, RM Mahdi, MB Dolinska, YV Sergeev, PT Wingfield, SH Kim, CE Egwuagu
Nature Medicine 2014
Vector platforms for gene therapy of inherited retinopathies
I Trapani, A Puppo, A Auricchio
Progress in Retinal and Eye Research 2014
Interferon-gamma (IFN-γ)-mediated retinal ganglion cell death in human tyrosinase T cell receptor transgenic mouse
S Husain, Y Abdul, C Webster, S Chatterjee, P Kesarwani, S Mehrotra
PloS one 2014
Suppressor of Cytokine Signaling 1 (SOCS1) Mitigates Anterior Uveitis and Confers Protection Against Ocular HSV-1 Infection
CR Yu, K Hayashi, YS Lee, RM Mahdi, DF Shen, CC Chan, CE Egwuagu
Inflammation 2014
Ocular Inflammation in Uveal Tract in Aged Obese Type 2 Diabetic Rats (Spontaneously Diabetic Torii Fatty Rats)
Y Kemmochi, K Miyajima, T Ohta, T Sasase, Y Yasui, K Toyoda, K Kakimoto, T Shoda, A Kakehashi
Journal of Diabetes Research 2014
Intraperitoneal infusion of mesenchymal stem/stromal cells prevents experimental autoimmune uveitis in mice
JY Oh, TW Kim, HJ Jeong, HJ Lee, JS Ryu, WR Wee, JW Heo, MK Kim
Mediators of Inflammation 2014
Autoimmune uveitis: a retrospective analysis of 104 patients from a tertiary reference center
M Prete, S Guerriero, R Dammacco, MC Fatone, A Vacca, F Dammacco, V Racanelli
Journal of Ophthalmic Inflammation and Infection 2014
Activation of Liver X Receptor Alleviates Ocular Inflammation in Experimental Autoimmune Uveitis
H Yang, S Zheng, Y Qiu, Y Yang, C Wang, P Yang, Q Li, B Lei
Investigative ophthalmology & visual science 2014
Prevalence of anti-retinal autoantibodies in different stages of Age-related macular degeneration
G Adamus, EY Chew, FL Ferris, ML Klein
BMC ophthalmology 2014
Flare up of rheumatoid arthritis associated with Vogt-Koyanagi-Harada syndrome treated with leflunomide
Jia Wang, Qi-Bing Xie, Yi Zhao, Yi Liu
International Journal of Ophthalmology 2014
Caveolin-1 Increases Proinflammatory Chemoattractants and Blood-Retinal Barrier Breakdown but Decreases Leukocyte Recruitment in Inflammation
X Li, X Gu, TM Boyce, M Zheng, AM Reagan, H Qi, N Mandal, AW Cohen, MC Callegan, DJ Carr, MH Elliott
Investigative ophthalmology & visual science 2014

Advertisement

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts

Picked up by 1 news outlets
Referenced in 4 patents
Referenced in 1 Wikipedia pages
Pinned by 1 on Pinterest
239 readers on Mendeley
See more details