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Citations to this article

EMT: When epithelial cells decide to become mesenchymal-like cells
Raghu Kalluri
Raghu Kalluri
Published June 1, 2009
Citation Information: J Clin Invest. 2009;119(6):1417-1419. https://doi.org/10.1172/JCI39675.
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Review Series Article has an altmetric score of 6

EMT: When epithelial cells decide to become mesenchymal-like cells

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Abstract

Epithelial-mesenchymal transition (EMT) is critical for appropriate embryonic development, and this process is re-engaged in adults during wound healing, tissue regeneration, organ fibrosis, and cancer progression. Inflammation is a crucial conspirator in the emergence of EMT in adults but is absent during embryonic development. As highlighted in this Review series, EMT is now a recognized mechanism for dispersing cells in embryos, forming fibroblasts/mesenchymal cells in injured tissues, and initiating metastasis of epithelial cancer cells. Also discussed are proposals to classify EMT into three subtypes, each of which has different functional consequences.

Authors

Raghu Kalluri

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Total citations by year

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Frontiers in immunology 2021
Comparison of circulating tumor cell (CTC) detection rates with epithelial cell adhesion molecule (EpCAM) and cell surface vimentin (CSV) antibodies in different solid tumors: a retrospective study
Y Gao, WH Fan, Z Song, H Lou, X Kang
PeerJ 2021
STAT3 as a Potential Target for Tumor Suppressive Effects of 15-Deoxy-δ 12,14 -prostaglandin J 2 in Triple Negative Breast Cancer
SJ Kim, NC Cho, YI Hahn, SH Kim, X Fang, YJ Surh
Journal of Cancer Prevention 2021
CUL4B Promotes Breast Carcinogenesis by Coordinating with Transcriptional Repressor Complexes in Response to Hypoxia Signaling Pathway
W Huang, J Zhang, M Huo, J Gao, T Yang, X Yin, P Wang, S Leng, D Feng, Y Chen, Y Yang, Y Wang
Advanced Science 2021
Clinical verification of vimentin/EpCAM immunolipid magnetic sorting system in monitoring CTCs in arterial and venous blood of advanced tumor
Y Liu, Q Li, T Chen, T Shen, X Zhang, P Song, L Liu, J Liu, T Jiang, X Liang
Journal of nanobiotechnology 2021
c-Jun N-terminal kinase 2 suppresses pancreatic cancer growth and invasion and is opposed by c-Jun N-terminal kinase 1
X Tian, B Traub, J Shi, N Huber, S Schreiner, G Chen, S Zhou, D Henne-Bruns, U Knippschild, M Kornmann
Cancer Gene Therapy 2021
The Fibronectin Expression Determines the Distinct Progressions of Malignant Gliomas via Transforming Growth Factor-Beta Pathway
CW Chen, CH Yang, YH Lin, YC Hou, TJ Cheng, ST Chang, YH Huang, ST Chung, CC Chio, YS Shan, HC Cheng, WT Chang
International journal of molecular sciences 2021
The miR-200 family in normal mammary gland development
MJ Roth, RA Moorehead
BMC Developmental Biology 2021
Prognostic and Therapeutic Significance of Circulating Tumor Cell Phenotype Detection Based on Epithelial-Mesenchymal Transition Markers in Early and Midstage Colorectal Cancer First-Line Chemotherapy
G Lu, Z Lu, C Li, X Huang, Q Luo, T Huang
Computational and mathematical methods in medicine 2021
Shooting at Moving and Hidden Targets—Tumour Cell Plasticity and the Notch Signalling Pathway in Head and Neck Squamous Cell Carcinomas
J Kałafut, A Czerwonka, A Anameriç, A Przybyszewska-Podstawka, JO Misiorek, A Rivero-Müller, M Nees
Cancers 2021
TGIF1 plays a carcinogenic role in esophageal squamous cell carcinoma through the Wnt/β‑catenin and Akt/mTOR signaling pathways
L Kong, Y Yu, H Guan, L Jiang, F Sun, X Li, W Huang, B Li
International journal of molecular medicine 2021
Crotoxin Modulates Events Involved in Epithelial–Mesenchymal Transition in 3D Spheroid Model
Kato EE, Sampaio SC
Toxins 2021
Anti-cancer adjuvant drug screening via epithelial-mesenchymal transition-related aptamer probe.
Wang HS, Xia X, Wang Y, Lyu W, Sang M, Gu C, Liu W, Zheng F
Analytical and Bioanalytical Chemistry 2021
Aquaporin-8 is a novel marker for progression of human cervical cancer cells.
Li W, Song Y, Pan C, Yu J, Zhang J, Zhu X
Cancer biomarkers : section A of Disease markers 2021
Reviewing cancer's biology: an eclectic approach.
Diori Karidio I, Sanlier SH
Journal of the Egyptian National Cancer Institute 2021
TGFβ biology in cancer progression and immunotherapy
R Derynck, SJ Turley, RJ Akhurst
Nature Reviews Clinical Oncology 2020
Molecular and cellular mechanisms of liver fibrosis and its regression
T Kisseleva, D Brenner
Nature Reviews Gastroenterology & Hepatology 2020
Influence of Fibroblasts on Mammary Gland Development, Breast Cancer Microenvironment Remodeling, and Cancer Cell Dissemination
A Avagliano, G Fiume, MR Ruocco, N Martucci, E Vecchio, L Insabato, D Russo, A Accurso, S Masone, S Montagnani, A Arcucci
Cancers 2020
Tight Junction Proteins and the Biology of Hepatobiliary Disease
N Roehlen, AA Suarez, HE Saghire, A Saviano, C Schuster, J Lupberger, TF Baumert
International journal of molecular sciences 2020
A Novel Model of Cancer Drug Resistance: Oncosomal Release of Cytotoxic and Antibody-Based Drugs
T Eguchi, EA Taha, SK Calderwood, K Ono
Biology : open access journal 2020
Mechanisms of liver fibrosis and its role in liver cancer
D Dhar, J Baglieri, T Kisseleva, DA Brenner
Experimental biology and medicine (Maywood, N.J.) 2020
Succinate Activates EMT in Intestinal Epithelial Cells through SUCNR1: A Novel Protagonist in Fistula Development
D Ortiz-Masiá, L Gisbert-Ferrándiz, C Bauset, S Coll, C Mamie, M Scharl, JV Esplugues, R Alós, F Navarro, J Cosín-Roger, MD Barrachina, S Calatayud
Cells 2020
Sarcomatoid renal cell carcinoma: biology, natural history and management
KA Blum, S Gupta, SK Tickoo, TA Chan, P Russo, RJ Motzer, JA Karam, AA Hakimi
Nature Reviews Urology 2020
Regulation of FN1 degradation by the p62/SQSTM1-dependent autophagy–lysosome pathway in HNSCC
X Liu, L Meng, X Li, D Li, Q Liu, Y Chen, X Li, W Bu, H Sun
International Journal of Oral Science 2020
Role of Epithelial-Mesenchymal Transition in Retinal Pigment Epithelium Dysfunction
M Zhou, JS Geathers, SL Grillo, SR Weber, W Wang, Y Zhao, JM Sundstrom
Frontiers in Cell and Developmental Biology 2020
Oxidative stress enhanced the transforming growth factor-β2-induced epithelial-mesenchymal transition through chemokine ligand 1 on ARPE-19 cell
IH Yang, JJ Lee, PC Wu, HK Kuo, YH Kuo, HM Huang
Scientific Reports 2020
The role of the tumor microenvironment in tumor cell intravasation and dissemination
L Borriello, GS Karagiannis, CL Duran, A Coste, MH Oktay, D Entenberg, JS Condeelis
European Journal of Cell Biology 2020
Fibroblast Growth Factor 21 Attenuates Diabetes-Induced Renal Fibrosis by Negatively Regulating TGF-β-p53-Smad2/3-Mediated Epithelial-to-Mesenchymal Transition via Activation of AKT
S Lin, L Yu, Y Ni, L He, X Weng, X Lu, C Zhang
Diabetes & Metabolism Journal 2020
Epigenetic silencing of the ubiquitin ligase subunit FBXL7 impairs c-SRC degradation and promotes epithelial-to-mesenchymal transition and metastasis
L Moro, D Simoneschi, E Kurz, AA Arbini, S Jang, N Guaragnella, S Giannattasio, W Wang, YA Chen, G Pires, A Dang, E Hernandez, P Kapur, A Mishra, A Tsirigos, G Miller, JT Hsieh, M Pagano
Nature Cell Biology 2020
Multifaceted WNT Signaling at the Crossroads Between Epithelial-Mesenchymal Transition and Autophagy in Glioblastoma
BP Coelho, CF de Lima Fernandes, JM Boccacino, MC Souza, MI Melo-Escobar, RN Alves, MB Prado, RP Iglesia, G Cangiano, GL Mazzaro, MH Lopes
Frontiers in Oncology 2020
15-Deoxy-Δ 12,14 -prostaglandin J 2 Induces Epithelial-tomesenchymal Transition in Human Breast Cancer Cells and Promotes Fibroblast Activation
J Choi, JY Suh, DH Kim, HK Na, YJ Surh
Journal of Cancer Prevention 2020
Local Delivery of Gemcitabine Inhibits Pancreatic and Cholangiocarcinoma Tumor Growth by Promoting Epidermal Growth Factor Receptor Degradation
SI Jang, S Fang, YY Baek, DH Lee, K Na, SY Lee, DK Lee
International journal of molecular sciences 2020
Evaluation of sensitivity and specificity of CanPatrol™ technology for detection of circulating tumor cells in patients with non-small cell lung cancer
J Li, Y Liao, Y Ran, G Wang, W Wu, Y Qiu, J Liu, N Wen, T Jing, H Wang, S Zhang
BMC Pulmonary Medicine 2020
The EMT transcription factor, Twist1, as a novel therapeutic target for pulmonary sarcomatoid carcinomas
T Liu, X Zhao, X Zheng, Y Zheng, X Dong, N Zhao, S Liao, B Sun
International journal of oncology 2020
Effect of Oral Losartan on Orthobiologics: Implications for Platelet-Rich Plasma and Bone Marrow Concentrate—A Rabbit Study
GY Nakama, S Gonzalez, P Matre, X Mu, KE Whitney, H Utsunomiya, JW Arner, MJ Philippon, S Ravuri, J Huard
International journal of molecular sciences 2020
The Role of Breast Cancer Stem Cell-Related Biomarkers as Prognostic Factors
CC Ko, WK Chia, GT Selvarajah, YK Cheah, YP Wong, GC Tan
Diagnostics 2020
Reproducibility of tumor budding assessment in pancreatic cancer based on a multicenter interobserver study
E Karamitopoulou, I Esposito, I Zlobec, AC Insilla, M Wartenberg, DF Schaeffer, S Kalloger, SL Rosa, C Sempoux, IR Centeno, P Lohneis
Virchows Archiv 2020
Generating cell-derived matrices from human trabecular meshwork cell cultures for mechanistic studies
Felix Yemanyi, Janice Vranka, VijayKrishna Raghunathan
Methods in cell biology 2020
Fibroblast Growth Factor 2 Augments Transforming Growth Factor Beta 1 Induced Epithelial-mesenchymal Transition in Lung Cell Culture Model
El-Baz LM, Shoukry NM, Hafez HS, Guzy RD, Salem ML
2020
CSN6 promotes the cell migration of breast cancer cells by positively regulating Snail1 stability.
Mou J, Wei L, Liang J, Du W, Pei D
International journal of medical sciences 2020
E‐cadherin‐Fc chimera protein matrix enhances cancer stem‐like properties and induces mesenchymal features in colon cancer cells
Y Qian, X Wu, Y Yokoyama, D Okuzaki, M Taguchi, H Hirose, J Wang, T Hata, A Inoue, M Hiraki, M Ohtsuka, H Takahashi, N Haraguchi, T Mizushima, S Tanaka, M Mori, H Yamamoto
Cancer Science 2019
New Insights into the Role of Epithelial–Mesenchymal Transition during Aging
F Santos, C Moreira, S Nóbrega-Pereira, BB de Jesus
International journal of molecular sciences 2019
Natural Plants Compounds as Modulators of Epithelial-to-Mesenchymal Transition
L Avila-Carrasco, P Majano, JA Sánchez-Toméro, R Selgas, M López-Cabrera, A Aguilera, GG Mateo
Frontiers in pharmacology 2019
PM2.5, Fine Particulate Matter: A Novel Player in the Epithelial-Mesenchymal Transition?
Z Xu, W Ding, X Deng
Frontiers in physiology 2019
Epigenetic Regulation of Inflammatory Cytokine-Induced Epithelial-To-Mesenchymal Cell Transition and Cancer Stem Cell Generation
GS Markopoulos, E Roupakia, KB Marcu, E Kolettas
Cells 2019
Estrogen Receptors in Epithelial-Mesenchymal Transition of Prostate Cancer
D Zazzo, Galasso, Giovannelli, D Donato, Bilancio, Perillo, Sinisi, Migliaccio, Castoria
Cancers 2019
Truncated O‐glycans promote epithelial‐to‐mesenchymal transition and stemness properties of pancreatic cancer cells
D Thomas, S Sagar, T Caffrey, PM Grandgenett, P Radhakrishnan
Journal of Cellular and Molecular Medicine 2019
The Role of Breast Cancer Stem Cells as a Prognostic Marker and a Target to Improve the Efficacy of Breast Cancer Therapy
MG Scioli, G Storti, F DAmico, P Gentile, G Fabbri, V Cervelli, A Orlandi
Cancers 2019
LncRNAs-directed PTEN enzymatic switch governs epithelial–mesenchymal transition
Q Hu, C Li, S Wang, Y Li, B Wen, Y Zhang, K Liang, J Yao, Y Ye, H Hsiao, TK Nguyen, PK Park, SD Egranov, DH Hawke, JR Marks, L Han, MC Hung, B Zhang, C Lin, L Yang
Cell Research 2019
The emerging roles of macrophages in cancer metastasis and response to chemotherapy
LR Sanchez, L Borriello, D Entenberg, JS Condeelis, MH Oktay, GS Karagiannis
Journal of leukocyte biology 2019
Epithelial to mesenchymal transition is mediated by both TGF-β canonical and non-canonical signaling during axolotl limb regeneration
F Sader, JF Denis, H Laref, S Roy
Scientific Reports 2019
Molecular Mechanisms and Bioavailability of Polyphenols in Prostate Cancer
T Costea, P Nagy, C Ganea, J Szöllősi, MM Mocanu
International journal of molecular sciences 2019
The splicing factor U2AF1 contributes to cancer progression through a noncanonical role in translation regulation
M Palangat, DG Anastasakis, DL Fei, KE Lindblad, R Bradley, CS Hourigan, M Hafner, DR Larson
Genes & development 2019
The Role of Fibrosis and Liver-Associated Fibroblasts in the Pathogenesis of Hepatocellular Carcinoma
J Baglieri, D Brenner, T Kisseleva
International journal of molecular sciences 2019
Short-term stimulation with histone deacetylase inhibitor trichostatin a induces epithelial-mesenchymal transition in nasopharyngeal carcinoma cells without increasing cell invasion ability
Z Shen, X Liao, Z Shao, M Feng, J Yuan, S Wang, S Gan, Y Ha, Z He, W Jie
BMC Cancer 2019
Role of cancer-associated fibroblasts in tumor structure, composition and the microenvironment in ovarian cancer (Review)
W Sun, S Fu
Oncology Letters 2019
FAM83A signaling induces epithelial-mesenchymal transition by the PI3K/AKT/Snail pathway in NSCLC
F Zhou, J Geng, S Xu, Q Meng, K Chen, F Liu, F Yang, B Pan, Y Yu
Aging 2019
Silencing Smad4 attenuates sensitivity of colorectal cancer cells to cetuximab by promoting epithelial‑mesenchymal transition
Z Lin, L Zhang, J Zhou, J Zheng
Molecular medicine reports 2019
Keep calm: the intestinal barrier at the interface of peace and war
L Thoo, M Noti, P Krebs
Cell Death and Disease 2019
Exposing the Underlying Relationship of Cancer Metastasis to Metabolism and Epithelial-Mesenchymal Transitions
X Kang, J Wang, C Li
iScience 2019
miR-1294 alleviates epithelial–mesenchymal transition by repressing FOXK1 in gastric cancer
Y Wang, G Liu, S Sun, J Qin
Genes & Genomics 2019
Impacts of Organomodified Nanoclays and Their Incinerated Byproducts on Bronchial Cell Monolayer Integrity
TA Stueckle, A White, A Wagner, RK Gupta, Y Rojanasakul, CZ Dinu
Chemical Research in Toxicology 2019
Clinical Scenarios Emerging from Combined Immunophenotypic, Molecular and Morphologic Analysis of Pancreatic Cancer: the Good, the Bad and the Ugly Scenario
Karamitopoulou, Gloor
Cancers 2019
Tumor Microenvironment of Metastasis (TMEM) Doorways Are Restricted to the Blood Vessel Endothelium in Both Primary Breast Cancers and Their Lymph Node Metastases
Ginter, Karagiannis, Entenberg, Lin, Condeelis, Jones, Oktay
Cancers 2019
The CRISPR-Cas9 crADSL HeLa transcriptome: A first step in establishing a model for ADSL deficiency and SAICAR accumulation
RC Mazzarino, V Baresova, M Zikánová, N Duval, TG Wilkinson, D Patterson, GN Vacano
Molecular Genetics and Metabolism Reports 2019

Circular RNA PVT1 promotes the invasion and epithelial–mesenchymal transition of breast cancer cells through serving as a competing endogenous RNA for miR-204-5p


Q Bian
OncoTargets and therapy 2019
Vitamin E TPGS based transferosomes augmented TAT as a promising delivery system for improved transdermal delivery of raloxifene
NA Alhakamy, UA Fahmy, OA Ahmed, X Yi
PloS one 2019
High stretchability, strength, and toughness of living cells enabled by hyperelastic vimentin intermediate filaments
J Hu, Y Li, Y Hao, T Zheng, SK Gupta, GA Parada, H Wu, S Lin, S Wang, X Zhao, RD Goldman, S Cai, M Guo
Proceedings of the National Academy of Sciences 2019
Transcriptional regulation of FoxM1 by HIF‑1α mediates hypoxia‑induced EMT in prostate cancer
C Tang, T Liu, K Wang, X Wang, S Xu, D He, J Zeng
Oncology reports 2019
New insights into the mechanisms of epithelial-mesenchymal transition and implications for cancer.
Dongre A, Weinberg RA
Nature reviews. Molecular cell biology 2019
Quasimesenchymal phenotype predicts systemic metastasis in pancreatic ductal adenocarcinoma.
Mahadevan KK, Arora KS, Amzallag A, Williams E, Kulkarni AS, Fernandez-Del Castillo C, Lillemoe KD, Bardeesy N, Hong TS, Ferrone CR, Ting DT, Deshpande V
Modern Pathology 2019
Coping with chemoresistance in prostate cancer—co-targeting of adipose stromal cells?
Bhagirath D, Saini S
Translational andrology and urology 2019
Tumour microenvironment of pancreatic cancer: immune landscape is dictated by molecular and histopathological features
Karamitopoulou E
British Journal of Cancer 2019
Nanotechnology in metastatic cancer treatment: Current Achievements and Future Research Trends.
Gonciar D, Mocan T, Matea CT, Zdrehus C, Mosteanu O, Mocan L, Pop T
Journal of Cancer 2019
p53-Autophagy-Metastasis Link
T Denisenko, A Pivnyuk, B Zhivotovsky
Cancers 2018
The role of the epithelial-to-mesenchymal transition (EMT) in diseases of the salivary glands
M Sisto, S Lisi, D Ribatti
Histochemistry and Cell Biology 2018
A kinome-wide high-content siRNA screen identifies MEK5–ERK5 signaling as critical for breast cancer cell EMT and metastasis
S Pavan, N Meyer-Schaller, M Diepenbruck, RK Kalathur, M Saxena, G Christofori
Oncogene 2018
Cellular sheddases are induced by Merkel cell polyomavirus small tumour antigen to mediate cell dissociation and invasiveness
N Nwogu, JR Boyne, SJ Dobson, K Poterlowicz, GE Blair, A Macdonald, J Mankouri, A Whitehouse, DA Galloway
PLoS pathogens 2018
Involvement of epithelial-mesenchymal transition in liver fibrosis
K Yu, Q Li, G Shi, N Li
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 2018
Caffeic Acid and Metformin Inhibit Invasive Phenotype Induced by TGF-β1 in C-4I and HTB-35/SiHa Human Cervical Squamous Carcinoma Cells by Acting on Different Molecular Targets
M Tyszka-Czochara, M Lasota, M Majka
International journal of molecular sciences 2018
Transfection of T-Box Transcription Factor BRACHYURY and SOX2 Synergistically Promote Self-Renewal and Invasive Phenotype in Oral Cancer Cells
N Akimoto, K Nakamura, H Hijioka, K Kume, Y Matsumura, T Sugiura
International journal of molecular sciences 2018
The TGF- β 1 Signaling Pathway as an Attractive Target in the Fibrosis Pathogenesis of Sjögren’s Syndrome
M Sisto, L Lorusso, G Ingravallo, R Tamma, D Ribatti, S Lisi
Mediators of Inflammation 2018
Tetrandrine suppresses adhesion, migration and invasion of human colon cancer SW620 cells via inhibition of nuclear factor-κB, matrix metalloproteinase-2 and matrix metalloproteinase-9 signaling pathways
TK Juan, KC Liu, CL Kuo, MD Yang, YL Chu, JL Yang, PP Wu, YP Huang, KC Lai, JG Chung
Oncology Letters 2018
Chemotherapy-induced metastasis: mechanisms and translational opportunities
GS Karagiannis, JS Condeelis, MH Oktay
Clinical & Experimental Metastasis 2018
Long non-coding RNA XLOC_000647 suppresses progression of pancreatic cancer and decreases epithelial-mesenchymal transition-induced cell invasion by down-regulating NLRP3
H Hu, Y Wang, X Ding, Y He, Z Lu, P Wu, L Tian, H Yuan, D Liu, G Shi, T Xia, J Yin, B Cai, Y Miao, K Jiang
Molecular Cancer 2018
A peek into cancer-associated fibroblasts: origins, functions and translational impact
VS LeBleu, R Kalluri
Disease models & mechanisms 2018
Capillary morphogenesis gene 2 maintains gastric cancer stem-like cell phenotype by activating a Wnt/β-catenin pathway
C Ji, L Yang, W Yi, D Xiang, Y Wang, Z Zhou, F Qian, Y Ren, W Cui, X Zhang, P Zhang, JM Wang, Y Cui, X Bian
Oncogene 2018
Detection of Epithelial-Mesenchymal Transition Status of Circulating Tumor Cells in Patients with Esophageal Squamous Carcinoma
D Han, K Chen, J Che, J Hang, H Li
BioMed Research International 2018
Glaucomatous cell derived matrices differentially modulate non-glaucomatous trabecular meshwork cellular behavior
VK Raghunathan, J Benoit, R Kasetti, G Zode, M Salemi, BS Phinney, KE Keller, JA Staverosky, CJ Murphy, T Acott, J Vranka
Acta Biomaterialia 2018
A novel mechanism of plasminogen activation in epithelial and mesenchymal cells
M Bydoun, A Sterea, IC Weaver, AD Bharadwaj, DM Waisman
Scientific Reports 2018
High glucose induces epithelial‑mesenchymal transition and results in the migration and invasion of colorectal cancer cells
J Wu, J Chen, , F Wang, H Sha, L Luo, Y Zhu, X Hong, S Bu
Experimental and therapeutic medicine 2018
Hypoxia-inducible transgelin 2 selects epithelial-to-mesenchymal transition and γ-radiation-resistant subtypes by focal adhesion kinase-associated insulin-like growth factor 1 receptor activation in non-small-cell lung cancer cells
IG Kim, JH Lee, SY Kim, HM Hwang, TR Kim, EW Cho
Cancer Science 2018
Global transcriptional analysis identifies a novel role for SOX4 in tumor-induced angiogenesis
SJ Vervoort, OG de Jong, MG Roukens, CL Frederiks, JF Vermeulen, AR Lourenço, L Bella, AT Vidakovic, JL Sandoval, C Moelans, M van Amersfoort, MJ Dallman, A Bruna, C Caldas, E Nieuwenhuis, E van der Wall, P Derksen, P van Diest, MC Verhaar, EW Lam, M Mokry, PJ Coffer
eLife 2018
Knockdown of FUT3 disrupts the proliferation, migration, tumorigenesis and TGF‑β induced EMT in pancreatic cancer cells
L Zhan, L Chen, Z Chen
Oncology Letters 2018
Foxf2 plays a dual role during transforming growth factor beta-induced epithelial to mesenchymal transition by promoting apoptosis yet enabling cell junction dissolution and migration
Meyer-Schaller N, Heck C, Tiede S, Yilmaz M, Christofori G
Breast Cancer Research 2018
Newly recognized extratumoral features of colorectal cancer challenge the current tumor-node-metastasis staging system
Athanasakis E, Xenaki S, Venianaki M, Chalkiadakis G, Chrysos E
Annals of Gastroenterology 2018
Effect of long non-coding RNA AOC4P on gastrointestinal stromal tumor cells.
Hu JC, Wang Q, Jiang LX, Cai L, Zhai HY, Yao ZW, Zhang ML, Feng Y
OncoTargets and therapy 2018
The role of cellular contact and TGF-beta signaling in the activation of the epithelial mesenchymal transition (EMT).
Gasior K, Wagner NJ, Cores J, Caspar R, Wilson A, Bhattacharya S, Hauck ML
Cell adhesion & migration 2018
Gland Attenuation, a Novel Morphological Feature of Colorectal Cancer: Evidence for an Epithelial-Mesenchymal Transition
Baek TH, Kang DW, Kim JH, Son HJ
Annals of Coloproctology 2018
SOX4 can redirect TGF-β-mediated SMAD3-transcriptional output in a context-dependent manner to promote tumorigenesis.
Vervoort SJ, Lourenço AR, Tufegdzic Vidakovic A, Mocholi E, Sandoval JL, Rueda OM, Frederiks C, Pals C, Peeters JGC, Caldas C, Bruna A, Coffer PJ
Nucleic Acids Research 2018
Mesenchymal marker and LGR5 expression levels in circulating tumor cells correlate with colorectal cancer prognosis.
Wang W, Wan L, Wu S, Yang J, Zhou Y, Liu F, Wu Z, Cheng Y
Cellular oncology (Dordrecht) 2018
Neutralization of IL-8 decreases tumor PMN-MDSCs and reduces mesenchymalization of claudin-low triple negative breast cancer
Charli Dominguez, Kristen McCampbell, Justin David, Claudia Palena
JCI Insight 2017
The role of autophagy in the cross-talk between epithelial-mesenchymal transitioned tumor cells and cancer stem-like cells
F Marcucci, P Ghezzi, C Rumio
Molecular Cancer 2017
Inflammation and Epithelial-Mesenchymal Transition in Pancreatic Ductal Adenocarcinoma: Fighting Against Multiple Opponents
M Khan, F Khalafalla
Cancer Growth and Metastasis 2017
miR-382 Contributes to Renal Tubulointerstitial Fibrosis by Downregulating HSPD1
Y Fang, T Xie, N Xue, Q Kuang, Z Wei, M Liang, X Ding
Oxidative medicine and cellular longevity 2017
CD109 released from human bone marrow mesenchymal stem cells attenuates TGF-β-induced epithelial to mesenchymal transition and stemness of squamous cell carcinoma
S Zhou, R Cecere, A Philip
Oncotarget 2017
Thymoquinone induces cytotoxicity and reprogramming of EMT in gastric cancer cells by targeting PI3K/Akt/mTOR pathway
LM Feng, XF Wang, QX Huang
Journal of Biosciences 2017
Epithelial-mesenchymal transition and inflammation at the site of the primary tumor
C Dominguez, JM David, C Palena
Seminars in Cancer Biology 2017
Myofibroblast transdifferentiation: The dark force in ocular wound healing and fibrosis
DY Shu, FJ Lovicu
Progress in Retinal and Eye Research 2017
Naproxen Inhibits UVB-induced Basal Cell and Squamous Cell Carcinoma Development in Ptch1 +/− /SKH-1 Hairless Mice
SC Chaudhary, M Waseem, M Rana, H Xu, L Kopelovich, CA Elmets, M Athar
Photochemistry and Photobiology 2017
Wnt Signaling in Chronic Rhinosinusitis with Nasal Polyps
R Böscke, EK Vladar, M Könnecke, B Hüsing, R Linke, R Pries, N Reiling, JD Axelrod, JV Nayak, B Wollenberg
American journal of respiratory cell and molecular biology 2017
Simulated microgravity triggers epithelial mesenchymal transition in human keratinocytes
D Ranieri, S Proietti, S Dinicola, MG Masiello, B Rosato, G Ricci, A Cucina, A Catizone, M Bizzarri, MR Torrisi
Scientific Reports 2017
The role of epithelial-mesenchymal transition in the post-lung transplantation bronchiolitis obliterans
C Zhang, Y Niu, L Yu, W Lv, H Xu, A Abuduwufuer, J Cao, J Hu
Journal of Cardiothoracic Surgery 2017
Suppression of Asparaginyl Endopeptidase Inhibits Polyomavirus Middle T Antigen-Induced Tumor Formation and Metastasis
C Xu, L Cao, J Liu, Z Qian, Y Peng, W Zhu, Y Qiu, Y Lin
Oncology research 2017
Up-Regulation of RFC3 Promotes Triple Negative Breast Cancer Metastasis and is Associated With Poor Prognosis Via EMT
ZY He, SG Wu, F Peng, Q Zhang, Y Luo, M Chen, Y Bao
Translational oncology 2017
miRNA-34c-5p inhibits amphiregulin-induced ovarian cancer stemness and drug resistance via downregulation of the AREG-EGFR-ERK pathway
SL Tung, WC Huang, FC Hsu, ZP Yang, TH Jang, JW Chang, CM Chuang, CR Lai, LH Wang
Oncogenesis 2017
Overexpression of A disintegrin and metalloprotease 10 promotes tumor proliferation, migration and poor prognosis in hypopharyngeal squamous cell carcinoma
C Ding, Q Zhang, Y Chen, X Zhang, P Wu, Z Zhang
Oncology reports 2017
Regulation of EMT in Colorectal Cancer: A Culprit in Metastasis
T Vu, P Datta
Cancers 2017
The effects of pleiotrophin in proliferative vitreoretinopathy
X Ding, Y Bai, X Zhu, T Li, E Jin, L Huang, W Yu, M Zhao
Graefe's Archive for Clinical and Experimental Ophthalmology 2017
Targeting fibronectin for cancer imaging and therapy
Z Han, ZR Lu
Journal of Materials Chemistry B 2017
Epithelial-to-mesenchymal transition in tumor progression
E Prieto-García, CV Díaz-García, I García-Ruiz, MT Agulló-Ortuño
Medical Oncology 2017
Impact of early subcultures on stemness, migration and angiogenic potential of adipose tissue-derived stem cells and their resistance to in vitro ischemic condition
H Faghih, A Javeri, MF Taha
Cytotechnology 2017
A step-by-step microRNA guide to cancer development and metastasis
GS Markopoulos, E Roupakia, M Tokamani, E Chavdoula, M Hatziapostolou, C Polytarchou, KB Marcu, AG Papavassiliou, R Sandaltzopoulos, E Kolettas
Cellular Oncology 2017
Combination Twist1 and CA15-3 in axillary lymph nodes for breast cancer prognosis
X Jiang, D Guo, W Li, T Yu, J Zhou, J Gong
Molecular medicine reports 2017
Novel predictors for lymph node metastasis in submucosal invasive colorectal carcinoma
K Yim, DD Won, IK Lee, ST Oh, ES Jung, SH Lee
World journal of gastroenterology : WJG 2017
TGF-β1 alters esophageal epithelial barrier function by attenuation of claudin-7 in eosinophilic esophagitis
N Nguyen, SD Fernando, KA Biette, JA Hammer, KE Capocelli, DA Kitzenberg, LE Glover, SP Colgan, GT Furuta, JC Masterson
Mucosal Immunology 2017
A missing link between RON expression and oncological outcomes in resected left-sided pancreatic cancer
D Han, C Kang, S Lee, H Hwang, W Lee
Oncology Letters 2017
Developmental pathways associated with cancer metastasis: Notch, Wnt, and Hedgehog
KA Nwabo, KP Takam, SR Tagne, L Vecchio, EP Seke, JM Muller, G Bassi, E Lukong, GR Kumar, AJ Mbo, M Krampera
Cancer biology & medicine 2017
Fibronectin induces epithelial-mesenchymal transition in human breast cancer MCF-7 cells via activation of calpain
CL Li, D Yang, X Cao, F Wang, DY Hong, J Wang, XC Shen, Y Chen
Oncology Letters 2017
Prognostic significance of ZEB1 and ZEB2 in digestive cancers: a cohort-based analysis and secondary analysis
H Chen, W Lu, C Huang, K Ding, D Xia, Y Wu, M Cai
Oncotarget 2017
Hypoxia induced Bcl-2/Twist1 complex promotes tumor cell invasion in oral squamous cell carcinoma
Y Duan, Q He, K Yue, H Si, J Wang, X Zhou, X Wang
Oncotarget 2017
Mesenchymal phenotype of circulating tumor cells is associated with distant metastasis in breast cancer patients
S Zhang, T Wu, X Peng, J Liu, F Liu, S Wu, S Liu, Y Dong, S Xie, S Ma
Cancer management and research 2017
Molecular regulation of epithelial-to-mesenchymal transition in tumorigenesis (Review)
H Škovierovï½, T Okajčekovï½, J Strnï½del, E Vidomanovï½, E Halašovï½
International journal of molecular medicine 2017
Using circulating tumor cells to advance precision medicine in prostate cancer
G Galletti, D Worroll, DM Nanus, P Giannakakou
Journal of Cancer Metastasis and Treatment 2017
CLDN-1 promoted the epithelial to migration and mesenchymal transition (EMT) in human bronchial epithelial cells via Notch pathway.
Lv J, Sun B, Mai Z, Jiang M, Du J
Molecular and Cellular Biochemistry 2017
Knockdown of TACC3 Inhibits the Proliferation and Invasion of Human Renal Cell Carcinoma Cells.
Guo F, Liu Y
Oncology research 2017
RBMS3 Inhibits the Proliferation and Metastasis of Breast Cancer Cells.
Yang Y, Quan L, Ling Y
Oncology research 2017
Knockdown of TMPRSS3, a Transmembrane Serine Protease, Inhibits Proliferation, Migration, and Invasion in Human Nasopharyngeal Carcinoma Cells.
Wang JY, Jin X, Li XF
Oncology research 2017
AKT-ions with a TWIST between EMT and MET
H Tang, D Massi, BA Hemmings, M Mandalà, Z Hu, A Wicki, G Xue
Oncotarget 2016
Interleukin-6 role in head and neck squamous cell carcinoma progression
MM Choudhary, TJ France, TN Teknos, P Kumar
World Journal of Otorhinolaryngology-Head and Neck Surgery 2016
Modes of invasion during tumour dissemination
P Pandya, JL Orgaz, V Sanz-Moreno
Molecular Oncology 2016
Novel roles of Src in cancer cell epithelial-to-mesenchymal transition, vascular permeability, microinvasion and metastasis
A Patel, H Sabbineni, A Clarke, PR Somanath
Life Sciences 2016
LYTAK1, a TAK1 inhibitor, suppresses proliferation and epithelial‑mesenchymal transition in retinal pigment epithelium cells
Z Chen, Y Mei, H Lei, R Tian, N Ni, F Han, S Gan, S Sun
Molecular medicine reports 2016
Epithelial–mesenchymal transition: a new target in anticancer drug discovery
F Marcucci, G Stassi, RD Maria
Nature Reviews Drug Discovery 2016
Identification of chromatin accessibility domains in human breast cancer stem cells
K Hardy, F Wu, W Tu, A Zafar, T Boulding, R McCuaig, CR Sutton, A Theodoratos, S Rao
Nucleus 2016
Developmental origin and lineage plasticity of endogenous cardiac stem cells
MP Santini, E Forte, RP Harvey, JC Kovacic
Development (Cambridge, England) 2016
Epac1 links prostaglandin E2 to β-catenin-dependent transcription during epithelial-to-mesenchymal transition
SR Jansen, WJ Poppinga, W Jager, F Lezoualc'h, X Cheng, T Wieland, SJ Yarwood, R Gosens, M Schmidt
Oncotarget 2016
Fractionated irradiation-induced EMT-like phenotype conferred radioresistance in esophageal squamous cell carcinoma
H Zhang, H Luo, Z Jiang, J Yue, Q Hou, R Xie, S Wu
Journal of Radiation Research 2016
Osteopontin—A Master Regulator of Epithelial-Mesenchymal Transition
A Kothari, M Arffa, V Chang, R Blackwell, WK Syn, J Zhang, Z Mi, P Kuo
Journal of Clinical Medicine 2016
Endothelial to mesenchymal transition (EndMT): an active process in Chronic Obstructive Pulmonary Disease (COPD)?
SS Sohal
Respiratory Research 2016
Stathmin1 overexpression in hypopharyngeal squamous cell carcinoma: A new promoter in FaDu cell proliferation and migration
Y Chen, Q Zhang, C Ding, X Zhang, X Qiu, Z Zhang
International journal of oncology 2016
Targeting epithelial-mesenchymal transition and cancer stem cells for chemoresistant ovarian cancer
J Deng, L Wang, H Chen, J Hao, J Ni, L Chang, W Duan, P Graham, Y Li
Oncotarget 2016
Wnt/β-catenin signaling plays an ever-expanding role in stem cell self-renewal, tumorigenesis and cancer chemoresistance
MK Mohammed, C Shao, J Wang, Q Wei, X Wang, Z Collier, S Tang, H Liu, F Zhang, J Huang, D Guo, M Lu, F Liu, J Liu, C Ma, LL Shi, A Athiviraham, TC He, MJ Lee
Genes & Diseases 2016
New Concepts on Pathogenesis and Diagnosis of Liver Fibrosis; A Review Article
H Ebrahimi, M Naderian, AA Sohrabpour
Middle East journal of digestive diseases 2016
Overexpression of HMGA2 promotes tongue cancer metastasis through EMT pathway
XP Zhao, H Zhang, JY Jiao, DX Tang, Y Wu, CB Pan
Journal of Translational Medicine 2016
NUMB negatively regulates the epithelial-mesenchymal transition of triple-negative breast cancer by antagonizing Notch signaling
J Zhang, X Shao, H Sun, K Liu, Z Ding, J Chen, L Fang, W Su, Y Hong, H Li, H Li
Oncotarget 2016
STC2 promotes the epithelial-mesenchymal transition of colorectal cancer cells through AKT-ERK signaling pathways
X Zeng, Y He, X Wang, Z Liang, J Liu, P Zhang, H Zhu, N Xu, S Liang
Oncotarget 2016
Advances in Clinical Chemistry
J Zhang, K Chen, ZH Fan
Advances in Clinical Chemistry 2016
Tumour-associated mesenchymal stem/stromal cells: emerging therapeutic targets
Y Shi, L Du, L Lin, Y Wang
Nature Reviews Drug Discovery 2016
Anti-Cancer Stem-like Cell Compounds in Clinical Development – An Overview and Critical Appraisal
F Marcucci, C Rumio, F Lefoulon
Frontiers in Oncology 2016
Nanoroughened adhesion-based capture of circulating tumor cells with heterogeneous expression and metastatic characteristics
W Chen, SG Allen, AK Reka, W Qian, S Han, J Zhao, L Bao, VG Keshamouni, SD Merajver, J Fu
BMC Cancer 2016
Oridonin inhibits pancreatic cancer cell migration and epithelial-mesenchymal transition by suppressing Wnt/β-catenin signaling pathway
QQ Liu, K Chen, Q Ye, XH Jiang, YW Sun
Cancer Cell International 2016
Losartan Attenuates Myocardial Endothelial-To-Mesenchymal Transition in Spontaneous Hypertensive Rats via Inhibiting TGF-β/Smad Signaling
M Wu, Z Peng, C Zu, J Ma, S Lu, J Zhong, S Zhang, M Bader
PloS one 2016
Signatures of breast cancer metastasis at a glance
GS Karagiannis, S Goswami, JG Jones, MH Oktay, JS Condeelis
Journal of cell science 2016
Regulation of epithelial-mesenchymal transition through epigenetic and post-translational modifications
SJ Serrano-Gomez, M Maziveyi, SK Alahari
Molecular Cancer 2016
MicroRNA Regulation of Epithelial to Mesenchymal Transition
M Abba, N Patil, J Leupold, H Allgayer
Journal of Clinical Medicine 2016
Can widely used cell type markers predict the suitability of immortalized or primary mammary epithelial cell models?
EC Ontsouka, JS Bertschi, X Huang, M Lüthi, S Müller, C Albrecht
Biological research 2016
Effect of Cigarette Smoking on Epithelial to Mesenchymal Transition (EMT) in Lung Cancer
T Vu, L Jin, P Datta
Journal of Clinical Medicine 2016
An improved strategy to detect the epithelial-mesenchymal transition process in circulating tumor cells in hepatocellular carcinoma patients
Y Liu, B Hu, Z Li, X He, Y Li, L Lu
Hepatology International 2016
Epigenetic regulation of epithelial–mesenchymal transition
L Sun, J Fang
Cellular and Molecular Life Sciences 2016
Cadherin-6 promotes EMT and cancer metastasis by restraining autophagy
M Gugnoni, V Sancisi, G Gandolfi, G Manzotti, M Ragazzi, D Giordano, I Tamagnini, M Tigano, A Frasoldati, S Piana, A Ciarrocchi
Oncogene 2016
Topoisomerase IIα mediates TCF-dependent epithelial–mesenchymal transition in colon cancer
Q Zhou, AD Abraham, L Li, A Babalmorad, S Bagby, JJ Arcaroli, RJ Hansen, FA Valeriote, DL Gustafson, J Schaack, WA Messersmith, DV LaBarbera
Oncogene 2016
Wnt signaling in cancer
T Zhan, N Rindtorff, M Boutros
Oncogene 2016
Establishment and characterization of a new feline mammary cancer cell line, FkMTp
A Borges, F Adega, R Chaves
Cytotechnology 2016
Effects of xanthine oxidase inhibition with febuxostat on the development of nephropathy in experimental type 2 diabetes: Febuxostat in diabetic nephropathy
R Komers, B Xu, J Schneider, TT Oyama
British Journal of Pharmacology 2016
Minimal residual disease in breast cancer: an overview of circulating and disseminated tumour cells
A Tachtsidis, LM McInnes, N Jacobsen, EW Thompson, CM Saunders
Clinical & Experimental Metastasis 2016
Small Interfering RNA Targeted to ASPP2 Promotes Progression of Experimental Proliferative Vitreoretinopathy
XL Chen, YJ Bai, QR Hu, SS Li, LZ Huang, XX Li
Mediators of Inflammation 2016
Parasympathetic neurogenesis is strongly associated with tumor budding and correlates with an adverse prognosis in pancreatic ductal adenocarcinoma
L Zhang, L Guo, M Tao, W Fu, D Xiu
Chinese Journal of Cancer Research 2016
Autophagy and epithelial–mesenchymal transition: an intricate interplay in cancer
M Gugnoni, V Sancisi, G Manzotti, G Gandolfi, A Ciarrocchi
Cell Death and Disease 2016
FGFR signaling maintains a drug persistent cell population following epithelial-mesenchymal transition
WS Brown, SS Akhand, MK Wendt
Oncotarget 2016
Cancer conundrum
RM Bavle, K Paremala
Journal of Oral and Maxillofacial Pathology : JOMFP 2016
FOXC2 augments tumor propagation and metastasis in osteosarcoma
MC Gozo, D Jia, PJ Aspuria, DJ Cheon, N Miura, AE Walts, BY Karlan, S Orsulic
Oncotarget 2016
MiR-155 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells through the activation of PI3K/SGK3/β-catenin signaling pathways
X Kong, F Liu, J Gao
Oncotarget 2016
MACC1 is post-transcriptionally regulated by miR-218 in colorectal cancer
K Ilm, S Fuchs, G Mudduluru, U Stein
Oncotarget 2016
 -Arrestin-1 Mediates Nicotine-Induced Metastasis through E2F1 Target Genes That Modulate Epithelial-Mesenchymal Transition
S Pillai, J Trevino, B Rawal, S Singh, M Kovacs, X Li, M Schell, E Haura, G Bepler, S Chellappan
Cancer research 2015
Bone marrow-derived fibrocytes contribute to liver fibrosis
J Xu, T Kisseleva
Experimental biology and medicine (Maywood, N.J.) 2015
Expression of pigment epithelium-derived factor is associated with a good prognosis and is correlated with epithelial-mesenchymal transition-related genes in infiltrating ductal breast carcinoma
D Zhou, M Zhang, P Xu, Y Yu, G Ye, L Zhang, A Wu
Oncology Letters 2015
The Role of Tyrosine Kinase Receptors in Peritoneal Fibrosis
L Wang, S Zhuang
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 2015
Aqueous and Alcoholic Extracts of Triphala and Their Active Compounds Chebulagic Acid and Chebulinic Acid Prevented Epithelial to Mesenchymal Transition in Retinal Pigment Epithelial Cells, by Inhibiting SMAD-3 Phosphorylation
S Sivasankar, R Lavanya, P Brindha, N Angayarkanni, Z Ablonczy
PloS one 2015
Classification of Circulating Tumor Cells by Epithelial-Mesenchymal Transition Markers
S Wu, S Liu, Z Liu, J Huang, X Pu, J Li, D Yang, H Deng, N Yang, J Xu, R Samant
PloS one 2015
The prognostic significance of bromodomain PHD-finger transcription factor in colorectal carcinoma and association with vimentin and E-cadherin
S Xiao, L Liu, X Lu, J Long, X Zhou, M Fang
Journal of Cancer Research and Clinical Oncology 2015
Involvement of ZEB1 and Snail1 in excessive production of extracellular matrix in Fuchs endothelial corneal dystrophy
N Okumura, R Minamiyama, LT Ho, ED Kay, S Kawasaki, T Tourtas, U Schlötzer-Schrehardt, FE Kruse, RD Young, AJ Quantock, S Kinoshita, N Koizumi
Laboratory Investigation 2015
TGF-βI Regulates Cell Migration through Pluripotent Transcription Factor OCT4 in Endometriosis
HK Au, JH Chang, YC Wu, YC Kuo, YH Chen, WC Lee, TS Chang, PC Lan, HC Kuo, KL Lee, MT Lee, CR Tzeng, YH Huang, R Zhou
PloS one 2015
Oncostatin-M Differentially Regulates Mesenchymal and Proneural Signature Genes in Gliomas via STAT3 Signaling
K Natesh, D Bhosale, A Desai, G Chandrika, R Pujari, J Jagtap, A Chugh, D Ranade, P Shastry
Neoplasia (New York, N.Y.) 2015
Histopathological features predict metastatic potential in locally advanced colon carcinomas
C Jayasinghe, N Simiantonaki, CJ Kirkpatrick
BMC Cancer 2015
Regulation of Epithelial-Mesenchymal Transition in Breast Cancer Cells by Cell Contact and Adhesion
D Radisky, M Cichon, C Nelson, D Radisky
Cancer informatics 2015
Bio-functionalized dense-silica nanoparticles for MR/NIRF imaging of CD146 in gastric cancer
P Wang, Y Qu, C Li, L Yin, C Shen, W Chen, S Yang, X Bian, D Fang
International Journal of Nanomedicine 2015
Modulation of CD44 Activity by A6-Peptide
M Finlayson
Frontiers in immunology 2015
Epithelial Plasticity in Cancer: Unmasking a MicroRNA Network for TGF- β -, Notch-, and Wnt-Mediated EMT
E Zoni, G der Pluijm, PC Gray, MK Julio
Journal of Oncology 2015
Regulation of complement-dependent cytotoxicity by TGF-β-induced epithelial–mesenchymal transition
MT Goswami, AK Reka, H Kurapati, V Kaza, J Chen, TJ Standiford, VG Keshamouni
Oncogene 2015
Using circulating tumor cells to inform on prostate cancer biology and clinical utility
J Li, SG Gregory, MA Garcia-Blanco, AJ Armstrong
Critical Reviews in Clinical Laboratory Sciences 2015
Silencing  3 Integrin by Targeted ECO/siRNA Nanoparticles Inhibits EMT and Metastasis of Triple-Negative Breast Cancer
JG Parvani, MD Gujrati, MA Mack, WP Schiemann, ZR Lu
Cancer research 2015
P4H9-detected molecule expression on spindle-shaped fibroblasts indicates malignant phenotype of colorectal cancer
S Yokoyama, J Ieda, N Yamamoto, S Yamaguchi, Y Mitani, A Takeuchi, K Takifuji, T Hotta, K Matsuda, T Watanabe, JE Shively, H Yamaue
British Journal of Cancer 2015
Expression of E-cadherin repressors SNAIL, ZEB1 and ZEB2 by tumour and stromal cells influences tumour-budding phenotype and suggests heterogeneity of stromal cells in pancreatic cancer
JA Galván, I Zlobec, M Wartenberg, A Lugli, B Gloor, A Perren, E Karamitopoulou
British Journal of Cancer 2015
Single-cell analyses of circulating tumor cells
Xi-Xi Chen, Fan Bai
Cancer biology & medicine 2015
Results of the Fifth Scientific Workshop of the ECCO (II): Pathophysiology of Perianal Fistulizing Disease
B Siegmund, RM Feakins, G Bamias, JC Ludvig, FV Teixeira, G Rogler, M Scharl
Journal of Crohn's & colitis 2015
Type II transglutaminase stimulates epidermal cancer stem cell epithelial-mesenchymal transition
ML Fisher, G Adhikary, W Xu, C Kerr, JW Keillor, RL Eckert
Oncotarget 2015
Expression of E-cadherin in oral lichen planus
Y Du, H Li
Experimental and therapeutic medicine 2015
In vitro 3-dimensional tumor model for radiosensitivity of HPV positive OSCC cell lines
M Zhang, B Rose, CS Lee, AM Hong
Cancer biology & therapy 2015
Pregnancy associated plasma protein-A links pregnancy and melanoma progression by promoting cellular migration and invasion.
Prithviraj P, Anaka M, McKeown SJ, Permezel M, Walkiewicz M, Cebon J, Behren A, Jayachandran A
Oncotarget 2015
Integrated gene and miRNA expression analysis of prostate cancer associated fibroblasts supports a prominent role for interleukin-6 in fibroblast activation.
Doldi V, Callari M, Giannoni E, D'Aiuto F, Maffezzini M, Valdagni R, Chiarugi P, Gandellini P, Zaffaroni N
Oncotarget 2015
Inflammation Fuels Tumor Progress and Metastasis
Liu J, Lin PC, Zhou BP
Current pharmaceutical design 2015
Role of Epithelial Mesenchymal Transition in Prostate Tumorigenesis
Khan MI, Hamid A, Adhami VM, Lall RK, Mukhtar H
Current pharmaceutical design 2015
Origin of myofibroblasts in the fibrotic liver in mice
K Iwaisako, C Jiang, M Zhang, M Cong, TJ Moore-Morris, TJ Park, X Liu, J Xu, P Wang, YH Paik, F Meng, M Asagiri, LA Murray, AF Hofmann, T Iida, CK Glass, DA Brenner, T Kisseleva
Proceedings of the National Academy of Sciences 2014
Inhibitory Role of the KEAP1-NRF2 Pathway in TGFβ1-Stimulated Renal Epithelial Transition to Fibroblastic Cells: A Modulatory Effect on SMAD Signaling
I Ryoo, H Ha, MK Kwak, R Mohanraj
PloS one 2014
The types of hepatic myofibroblasts contributing to liver fibrosis of different etiologies
J Xu, X Liu, Y Koyama, P Wang, T Lan, IG Kim, IH Kim, HY Ma, T Kisseleva
Frontiers in pharmacology 2014
Medical therapy of stricturing Crohn’s disease: what the gut can learn from other organs - a systematic review
D Bettenworth, F Rieder
Fibrogenesis & Tissue Repair 2014
The network of epithelial–mesenchymal transition: potential new targets for tumor resistance
D Nantajit, D Lin, JJ Li
Journal of Cancer Research and Clinical Oncology 2014
Claudin-7 expression induces mesenchymal to epithelial transformation (MET) to inhibit colon tumorigenesis
AA Bhat, JL Pope, JJ Smith, R Ahmad, X Chen, MK Washington, RD Beauchamp, AB Singh, P Dhawan
Oncogene 2014
Platelet-Derived Growth Factor BB Mimics Serum-Induced Dispersal of Pancreatic Epithelial Cell Clusters: PDGF DISPERSES PANCREATIC CELL CLUSTERS
S Hiram-Bab, LS Katz, H Shapira, J Sandbank, MC Gershengorn, Y Oron
Journal of Cellular Physiology 2014
Cellular and molecular mechanisms in the pathogenesis of liver fibrosis: An update
GÖ Elpek
World journal of gastroenterology : WJG 2014
When Good Turns Bad: Regulation of Invasion and Metastasis by ErbB2 Receptor Tyrosine Kinase
D Brix, K Clemmensen, T Kallunki
Cells 2014
Membrane Proteins Involved in Epithelial-Mesenchymal Transition and Tumor Invasion: Studies on TMPRSS4 and TM4SF5
S Kim, JW Lee
Genomics & Informatics 2014
A randomized controlled trial of inhaled corticosteroids (ICS) on markers of epithelial-mesenchymal transition (EMT) in large airway samples in COPD: an exploratory proof of concept study
SS Sohal, A Soltani, D Reid, C Ward, KE Wills, HK Muller, EH Walters
International journal of chronic obstructive pulmonary disease 2014
Micro-management of pluripotent stem cells
WT Guo, XW Wang, Y Wang
Protein & Cell 2014
Clinical significance of epithelial mesenchymal transition (EMT) in chronic obstructive pulmonary disease (COPD): potential target for prevention of airway fibrosis and lung cancer
SS Sohal, MQ Mahmood, EH Walters
Clinical and Translational Medicine 2014
Suppression of epithelial–mesenchymal transition and apoptotic pathways by miR-294/302 family synergistically blocks let-7-induced silencing of self-renewal in embryonic stem cells
WT Guo, XW Wang, YL Yan, YP Li, X Yin, Q Zhang, C Melton, A Shenoy, NA Reyes, SA Oakes, R Blelloch, Y Wang
Cell Death and Differentiation 2014
Human Equilibrative Nucleoside Transporter-1 Knockdown Tunes Cellular Mechanics through Epithelial-Mesenchymal Transition in Pancreatic Cancer Cells
Y Lee, EJ Koay, W Zhang, L Qin, DK Kirui, F Hussain, H Shen, M Ferrari, XY Guan
PloS one 2014
Cancer-associated fibroblasts in digestive tumors
Lei Huang, Lei Huang, A. Man Xu, Sha Liu, Wei Liu, Wei Liu, Tuan Jie Li
World Journal of Gastroenterology 2014
Inflammatory cues acting on the adult intestinal stem cells and the early onset of cancer (review)
AD Barbaro, G Perletti, IM Bonapace, E Monti
International journal of oncology 2014
The Role of Uric Acid in Kidney Fibrosis: Experimental Evidences for the Causal Relationship
IY Kim, DW Lee, SB Lee, IS Kwak
BioMed Research International 2014
Molecular analysis of circulating tumour cells—biology and biomarkers
MG Krebs, RL Metcalf, L Carter, G Brady, FH Blackhall, C Dive
Nature Reviews Clinical Oncology 2014
The RON Receptor Tyrosine Kinase in Pancreatic Cancer Pathogenesis and Its Potential Implications for Future Targeted Therapies:
CM Kang, ML Babicky, AM Lowy
Pancreas 2014
Loss of myoferlin redirects breast cancer cell motility towards collective migration
LI Volakis, R Li, WE 4th, C Mihai, M Bechel, TL Summerfield, CS Ahn, HM Powell, R Zielinski, TJ Rosol, SN Ghadiali, DA Kniss
PloS one 2014
Regulation of microRNAs in cancer metastasis
JM Bouyssou, S Manier, D Huynh, S Issa, AM Roccaro, IM Ghobrial
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 2014
The promise of circulating tumor cell analysis in cancer management
J Mateo, M Gerlinger, D Rodrigues, JS de Bono
Genome biology 2014
Wilms' tumor protein induces an epithelial-mesenchymal hybrid differentiation state in clear cell renal cell carcinoma
VB Sampson, JM David, I Puig, PU Patil, AG de Herreros, GV Thomas, AK Rajasekaran
PloS one 2014
Study on the Biological Characteristics of CD133 (+) Cells Interfered by RNA Interference in Gastric Cancer
JW Yu, SL Wang, JG Wu, RQ Lu, XC Ni, C Cai, BJ Jiang
ISRN Gastroenterology 2014
MiR-506 inhibits multiple targets in the epithelial-to-mesenchymal transition network and is associated with good prognosis in epithelial ovarian cancer: MiR-506 inhibits EMT through multiple targets in OvCa
Y Sun, L Hu, H Zheng, M Bagnoli, Y Guo, R Rupaimoole, C Rodriguez-Aguayo, G Lopez-Berestein, P Ji, K Chen, AK Sood, D Mezzanzanica, J Liu, B Sun, W Zhang
The Journal of Pathology 2014
Live Imaging and Gene Expression Analysis in Zebrafish Identifies a Link between Neutrophils and Epithelial to Mesenchymal Transition
CM Freisinger, A Huttenlocher, O Wever
PloS one 2014
FHIT Suppresses Epithelial-Mesenchymal Transition (EMT) and Metastasis in Lung Cancer through Modulation of MicroRNAs
SS Suh, JY Yoo, R Cui, B Kaur, K Huebner, TK Lee, RI Aqeilan, CM Croce, MS Horwitz
PLoS genetics 2014
To "Grow" or "Go": TMEM16A Expression as a Switch between Tumor Growth and Metastasis in SCCHN
DJ Shiwarski, C Shao, A Bill, J Kim, D Xiao, CA Bertrand, RS Seethala, D Sano, JN Myers, P Ha, J Grandis, LA Gaither, MA Puthenveedu, U Duvvuri
Clinical cancer research 2014
Transglutaminase Regulation of Cell Function
RL Eckert, MT Kaartinen, M Nurminskaya, AM Belkin, G Colak, GV Johnson, K Mehta
Physiological reviews 2014
Alteration of N-glycans and Expression of Their Related Glycogenes in the Epithelial-Mesenchymal Transition of HCV29 Bladder Epithelial Cells
J Guo, X Li, Z Tan, W Lu, G Yang, F Guan
Molecules (Basel, Switzerland) 2014
MiR-506: A Multitasker in Suppression of the Epithelial-to-Mesenchymal Transition
Sun Y, Mezzanzanica D, Zhang W
2014
Aberrant expression of the embryonic transcription factor brachyury in human tumors detected with a novel rabbit monoclonal antibody
Hamilton DH, Fernando RI, Schlom J, Palena C
Oncotarget 2014
Tissue remodelling in chronic bronchial diseases: from the epithelial to mesenchymal phenotype
Pain M, Bermudez O, Lacoste P, Royer PJ, Botturi K, Tissot A, Brouard S, Eickelberg O, Magnan A
European Respiratory Review 2014
KLF6-SV1 Drives Breast Cancer Metastasis and Is Associated with Poor Survival
R Hatami, AM Sieuwerts, S Izadmehr, Z Yao, RF Qiao, L Papa, MP Look, M Smid, J Ohlssen, AC Levine, D Germain, D Burstein, A Kirschenbaum, A DiFeo, JA Foekens, G Narla
Science Translational Medicine 2013
Scleroderma pathogenesis: a pivotal role for fibroblasts as effector cells
AJ Gilbane, CP Denton, AM Holmes
Arthritis Research & Therapy 2013
KCa3.1 mediates activation of fibroblasts in diabetic renal interstitial fibrosis
C Huang, S Shen, Q Ma, A Gill, CA Pollock, XM Chen
Nephrology Dialysis Transplantation 2013
c-Jun N-Terminal Kinases Mediate a Wide Range of Targets in the Metastatic Cascade
ND Ebelt, MA Cantrell, CL van Berg
Genes & cancer 2013
A mechanism for epithelial-mesenchymal transition and anoikis resistance in breast cancer triggered by zinc channel ZIP6 and STAT3 (signal transducer and activator of transcription 3)
C Hogstrand, P Kille, ML Ackland, S Hiscox, KM Taylor
Biochemical Journal 2013
Inhibiting cycloxygenase and ornithine decarboxylase by diclofenac and alpha-difluoromethylornithine blocks cutaneous SCCs by targeting Akt-ERK axis
A Arumugam, Z Weng, SS Talwelkar, SC Chaudhary, L Kopelovich, CA Elmets, F Afaq, M Athar
PloS one 2013
Erb-041, an Estrogen Receptor-  Agonist, Inhibits Skin Photocarcinogenesis in SKH-1 Hairless Mice by Downregulating the WNT Signaling Pathway
SC Chaudhary, T Singh, SS Talwelkar, RK Srivastava, A Arumugam, Z Weng, CA Elmets, F Afaq, L Kopelovich, M Athar
Cancer prevention research (Philadelphia, Pa.) 2013
Epithelial-mesenchymal Transition---A Hallmark of Breast Cancer Metastasis
Y Wang, BP Zhou
2013
Role of fucosyltransferase IV in epithelial-mesenchymal transition in breast cancer cells
X Yang, S Liu, Q Yan
Cell Death and Disease 2013
Pathogenic mechanisms in HBV- and HCV-associated hepatocellular carcinoma
A Arzumanyan, HM Reis, MA Feitelson
Nature Reviews Cancer 2013
The metastasis-promoting roles of tumor-associated immune cells
HA Smith, Y Kang
Journal of Molecular Medicine 2013
Evidence for and against epithelial-to-mesenchymal transition in the liver
G Xie, AM Diehl
AJP Gastrointestinal and Liver Physiology 2013
Cadherin 6 is a new RUNX2 target in TGF-β signalling pathway
V Sancisi, G Gandolfi, M Ragazzi, D Nicoli, I Tamagnini, S Piana, A Ciarrocchi
PloS one 2013
L-Proline Induces a Mesenchymal-like Invasive Program in Embryonic Stem Cells by Remodeling H3K9 and H3K36 Methylation
S Comes, M Gagliardi, N Laprano, A Fico, A Cimmino, A Palamidessi, D De Cesare, S De Falco, C Angelini, G Scita, EJ Patriarca, MR Matarazzo, G Minchiotti
Stem Cell Reports 2013
Tissue-based identification of stem cells and epithelial-to-mesenchymal transition in breast cancer
TE Anwar, CG Kleer
Human Pathology 2013
Lipopolysaccharide induces a fibrotic-like phenotype in endothelial cells
C Echeverría, I Montorfano, D Sarmiento, A Becerra, F Nuñez-Villena, XF Figueroa, C Cabello-Verrugio, AA Elorza, C Riedel, F Simon
Journal of Cellular and Molecular Medicine 2013
Loss of N-Myc interactor promotes epithelial–mesenchymal transition by activation of TGF-β/SMAD signaling
DJ Devine, JW Rostas, BJ Metge, S Das, MS Mulekar, JA Tucker, WE Grizzle, DJ Buchsbaum, LA Shevde, RS Samant
Oncogene 2013
Mammary epithelial cell interactions with fibronectin stimulate epithelial-mesenchymal transition
J Park, JE Schwarzbauer
Oncogene 2013
Epithelial-mesenchymal transition and migration of prostate cancer stem cells is driven by cancer-associated fibroblasts in an HIF-1α/β-catenin-dependent pathway
Y Luo, L Lan, YG Jiang, JH Zhao, MC Li, NB Wei, YH Lin
Molecules and Cells 2013
Immunotherapy Exposes Cancer Stem Cell Resistance and a New Synthetic Lethality
L Radvanyi
Molecular Therapy 2013
An in vivo RNAi screen identifies SALL1 as a tumor suppressor in human breast cancer with a role in CDH1 regulation
J Wolf, K Müller-Decker, C Flechtenmacher, F Zhang, M Shahmoradgoli, GB Mills, JD Hoheisel, M Boettcher
Oncogene 2013
Role of epithelial-mesenchymal transition in pancreatic ductal adenocarcinoma: is tumor budding the missing link?
E Karamitopoulou
Frontiers in Oncology 2013
TACC3 is essential for EGF-mediated EMT in cervical cancer
GH Ha, JL Kim, EK Breuer
PloS one 2013
The roles of Notch1 expression in the migration of intrahepatic cholangiocarcinoma
Q Zhou, Y Wang, B Peng, L Liang, J Li
BMC Cancer 2013
Sustained elevation of Snail promotes glial-mesenchymal transition after irradiation in malignant glioma
R Mahabir, M Tanino, A Elmansuri, L Wang, T Kimura, T Itoh, Y Ohba, H Nishihara, H Shirato, M Tsuda, S Tanaka
Neuro-Oncology 2013
Decoding Information in Cell Shape
P Rangamani, A Lipshtat, EU Azeloglu, RC Calizo, M Hu, S Ghassemi, J Hone, S Scarlata, SR Neves, R Iyengar
Cell 2013
Digestive cancer surgery in the era of sentinel node and epithelial-mesenchymal transition
N Peparini
World journal of gastroenterology : WJG 2013
Loss of Raf-1 kinase inhibitor protein (RKIP) is strongly associated with high-grade tumor budding and correlates with an aggressive phenotype in pancreatic ductal adenocarcinoma (PDAC)
E Karamitopoulou, I Zlobec, B Gloor, A Kondi-Pafiti, A Lugli, A Perren
Journal of Translational Medicine 2013
Targeted inactivation of β1 integrin induces β3 integrin switching, which drives breast cancer metastasis by TGF-β
JG Parvani, AJ Galliher-Beckley, BJ Schiemann, WP Schiemann
Molecular biology of the cell 2013
Thrombin promotes epithelial ovarian cancer cell invasion by inducing epithelial-mesenchymal transition
YC Zhong, T Zhang, W Di, WP Li
Journal of Gynecologic Oncology 2013
IL-10 treatment is associated with prohibitin expression in the Crohn's disease intestinal fibrosis mouse model
C Yuan, WX Chen, JS Zhu, NW Chen, YM Lu, YX Ou, HQ Chen
Mediators of Inflammation 2013
Tissue transglutaminase as a central mediator in inflammation-induced progression of breast cancer
N Agnihotri, S Kumar, K Mehta
Breast Cancer Research 2013
Constitutively active androgen receptor variants upregulate expression of mesenchymal markers in prostate cancer cells
F Cottard, I Asmane, E Erdmann, JP Bergerat, JE Kurtz, J Céraline
PloS one 2013
The NF-κB RelB protein is an oncogenic driver of mesenchymal glioma
DW Lee, D Ramakrishnan, J Valenta, IF Parney, KJ Bayless, R Sitcheran
PloS one 2013
A historical to present-day account of efforts to answer the question: "what puts the brakes on mammalian hair cell regeneration?"
JC Burns, JT Corwin
Hearing Research 2013
Tumor budding cells, cancer stem cells and epithelial-mesenchymal transition-type cells in pancreatic cancer
E Karamitopoulou
Frontiers in Oncology 2013
A Brief Review of the Biophysical Hallmarks of Metastatic Cancer Cells
W Zhang, K Kai, NT Ueno, L Qin
Cancer hallmarks 2013
Small Rho GTPases in the control of cell shape and mobility.
Murali A, Rajalingam K
Cellular and molecular life sciences : CMLS 2013
Sources of myofibroblasts in kidney fibrosis: all answers are correct, however to different extent!
Ballhause TM, Soldati R, Mertens PR
International Urology and Nephrology 2013
On the origin of cancer metastasis.
Seyfried TN, Huysentruyt LC
Critical Reviews in Oncogenesis 2013
Klotho suppresses tumor progression via inhibiting PI3K/Akt/GSK3β/Snail signaling in renal cell carcinoma
Zhu Y, Xu L, Zhang J, Xu W, Liu Y, Yin H, Lv T, An H, Liu L, He H, Zhang H, Liu J, Xu J, Lin Z
Cancer Science 2013
Proteomic Signatures of the Desmoplastic Invasion Front Reveal Collagen Type XII as a Marker of Myofibroblastic Differentiation During Colorectal Cancer Metastasis
GS Karagiannis, C Petraki, I Prassas, P Saraon, N Musrap, A Dimitromanolakis, EP Diamandis
Oncotarget 2012
Complex Regulation of the Pericellular Proteolytic Microenvironment during Tumor Progression and Wound Repair: Functional Interactions between the Serine Protease and Matrix Metalloproteinase Cascades
CE Wilkins-Port, SP Higgins, CE Higgins, I Kobori-Hotchkiss, PJ Higgins
Biochemistry Research International 2012
Tubular expression of heat shock protein 27 inhibits fibrogenesis in obstructive nephropathy
A Vidyasagar, S Reese, O Hafez, LJ Huang, W Swain, L Jacobson, J Torrealba, PE Chammas, NA Wilson, A Djamali
Kidney International 2012
Epithelial-Mesenchymal Transition, TGF-β, and Osteopontin in Wound Healing and Tissue Remodeling After Injury:
CE Weber, NY Li, PY Wai, PC Kuo
Journal of Burn Care & Research 2012
Pericyte Depletion Results in Hypoxia-Associated Epithelial-to-Mesenchymal Transition and Metastasis Mediated by Met Signaling Pathway
VG Cooke, VS LeBleu, D Keskin, Z Khan, JT O'Connell, Y Teng, MB Duncan, L Xie, G Maeda, S Vong, H Sugimoto, RM Rocha, A Damascena, RR Brentani, R Kalluri
Cancer Cell 2012
Fibrocytes and the pathogenesis of diffuse parenchymal lung disease
B Mehrad, RM Strieter
Fibrogenesis & Tissue Repair 2012
What's new in liver fibrosis? The origin of myofibroblasts in liver fibrosis: The origin of myofibroblasts
K Iwaisako, DA Brenner, T Kisseleva
Journal of Gastroenterology and Hepatology 2012
Tissue transglutaminase constitutively activates HIF-1α promoter and nuclear factor-κB via a non-canonical pathway
S Kumar, K Mehta
PloS one 2012
EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer
AM Haslehurst, M Koti, M Dharsee, P Nuin, K Evans, J Geraci, T Childs, J Chen, J Li, J Weberpals, S Davey, J Squire, PC Park, H Feilotter
BMC Cancer 2012
Eosinophilic esophagitis: Epithelial mesenchymal transition contributes to esophageal remodeling and reverses with treatment
AF Kagalwalla, N Akhtar, SA Woodruff, BA Rea, JC Masterson, V Mukkada, KR Parashette, J Du, S Fillon, CA Protheroe, JJ Lee, K Amsden, H Melin-Aldana, KE Capocelli, GT Furuta, SJ Ackerman
Journal of Allergy and Clinical Immunology 2012
The T-box transcription factor Brachyury regulates epithelial-mesenchymal transition in association with cancer stem-like cells in adenoid cystic carcinoma cells
M Shimoda, T Sugiura, I Imajyo, K Ishii, S Chigita, K Seki, Y Kobayashi, K Shirasuna
BMC Cancer 2012
T-box transcription factor Brachyury expression is correlated with epithelial-mesenchymal transition and lymph node metastasis in oral squamous cell carcinoma
I Imajyo, T Sugiura, Y Kobayashi, M Shimoda, K Ishii, N Akimoto, N Yoshihama, I Kobayashi, Y Mori
International journal of oncology 2012
CCN5/WISP-2: A micromanager of breast cancer progression
SK Banerjee, S Banerjee
Journal of Cell Communication and Signaling 2012
Role of microRNAs in the Regulation of Breast Cancer Stem Cells
S Liu, SG Clouthier, MS Wicha
Journal of Mammary Gland Biology and Neoplasia 2012
Evidence that GTP-binding domain but not catalytic domain of transglutaminase 2 is essential for epithelial-to-mesenchymal transition in mammary epithelial cells
A Kumar, J Xu, B Sung, S Kumar, D Yu, BB Aggarwal, K Mehta
Breast Cancer Research 2012
Tumour budding: a promising parameter in colorectal cancer
A Lugli, E Karamitopoulou, I Zlobec
British Journal of Cancer 2012
Selection of Mesenchymal-Like Metastatic Cells in Primary Tumors – An in silico Investigation
V Narang, SY Wong, SR Leong, B Harish, JP Abastado, A Gouaillard
Frontiers in immunology 2012
One-Step Derivation of Mesenchymal Stem Cell (MSC)-Like Cells from Human Pluripotent Stem Cells on a Fibrillar Collagen Coating
Y Liu, AJ Goldberg, JE Dennis, GA Gronowicz, LT Kuhn
PloS one 2012
MUC4 potentiates invasion and metastasis of pancreatic cancer cells through stabilization of fibroblast growth factor receptor 1
S Rachagani, MA Macha, MP Ponnusamy, D Haridas, S Kaur, M Jain, SK Batra
Carcinogenesis 2012
TWIST1 associates with NF-κB subunit RELA via carboxyl-terminal WR domain to promote cell autonomous invasion through IL8 production
S Li, SE Kendall, R Raices, J Finlay, M Covarrubias, Z Liu, G Lowe, YH Lin, YH Teh, V Leigh, S Dhillon, S Flanagan, KS Aboody, CA Glackin
BMC Biology 2012
The reactive stroma microenvironment and prostate cancer progression
DA Barron, DR Rowley
Endocrine Related Cancer 2012
MicroRNA-200 family modulation in distinct breast cancer phenotypes
MÁ Castilla, J Díaz-Martín, D Sarrió, L Romero-Pérez, MÁ López-García, B Vieites, M Biscuola, S Ramiro-Fuentes, CM Isacke, J Palacios
PloS one 2012
Cancer stem cells, tumor dormancy, and metastasis
P Patel, EI Chen
Frontiers in Endocrinology 2012
N-cadherin expression in malignant germ cell tumours of the testis
F Bremmer, B Hemmerlein, A Strauss, P Burfeind, P Thelen, HJ Radzun, CL Behnes
BMC clinical pathology 2012
N-cadherin is differentially expressed in histological subtypes of papillary renal cell carcinoma
CL Behnes, B Hemmerlein, A Strauss, HJ Radzun, F Bremmer
Diagnostic Pathology 2012
Nickel-induced epithelial-mesenchymal transition by reactive oxygen species generation and E-cadherin promoter hypermethylation
CH Wu, SC Tang, PH Wang, H Lee, JL Ko
The Journal of biological chemistry 2012
Cancer-Associated Fibroblasts Drive the Progression of Metastasis through both Paracrine and Mechanical Pressure on Cancer Tissue
GS Karagiannis, T Poutahidis, SE Erdman, R Kirsch, RH Riddell, EP Diamandis
Molecular cancer research : MCR 2012
Suppression of the Epithelial–Mesenchymal Transition by Grainyhead-like-2
B Cieply, P Riley, PM Pifer, J Widmeyer, JB Addison, AV Ivanov, J Denvir, SM Frisch
Cancer research 2012
Erg is a crucial regulator of endocardial-mesenchymal transformation during cardiac valve morphogenesis
P Vijayaraj, AL Bras, N Mitchell, M Kondo, S Juliao, M Wasserman, D Beeler, K Spokes, WC Aird, HS Baldwin, P Oettgen
Development (Cambridge, England) 2012
Hepatitis B virus X protein promotes hepatoma cell invasion and metastasis by stabilizing Snail protein.
Liu H, Xu L, He H, Zhu Y, Liu J, Wang S, Chen L, Wu Q, Xu J, Gu J
Cancer Science 2012
Bone marrow-derived myofibroblasts are the providers of pro-invasive matrix metalloproteinase 13 in primary tumor.
Lecomte J, Masset A, Blacher S, Maertens L, Gothot A, Delgaudine M, Bruyère F, Carnet O, Paupert J, Illemann M, Foidart JM, Lund IK, Høyer-Hansen G, Noel A
Neoplasia (New York, N.Y.) 2012
BVES regulates epithelial-mesenchymal phenotypes and is silenced via promoter methylation in human epithelial malignancy
Christopher Williams, Baolin Zhang, J. Joshua Smith, Ashwath Jayagopal, Caitlyn Barrett, Christopher Pino, Patricia Russ, Sai Presley, DunFa Peng, Daniel Rosenblatt, Rick Haselton, Jin-Long Yang, M. Kay Washington, Xi Chen, Steven Eschrich, Timothy Yeatman, Wael El-Rifai, R. Daniel Beauchamp, Min Chang
Journal of Clinical Investigation 2011
Phenotype-dependent production of des-γ-carboxy prothrombin in hepatocellular carcinoma
H Suzuki, K Murata, T Gotoh, M Kusano, H Okano, T Oyamada, Y Yasuda, M Imamura, M Kudo, M Mizokami, A Sakamoto
Journal of Gastroenterology 2011
ID1 Facilitates the Growth and Metastasis of Non-Small Cell Lung Cancer in Response to Nicotinic Acetylcholine Receptor and Epidermal Growth Factor Receptor Signaling▿
S Pillai, W Rizwani, X Li, B Rawal, S Nair, MJ Schell, G Bepler, E Haura, D Coppola, S Chellappan
Molecular and cellular biology 2011
Suppression of microRNA-29 Expression by TGF- β 1 Promotes Collagen Expression and Renal Fibrosis
B Wang, R Komers, R Carew, CE Winbanks, B Xu, M Herman-Edelstein, P Koh, M Thomas, K Jandeleit-Dahm, P Gregorevic, ME Cooper, P Kantharidis
Journal of the American Society of Nephrology : JASN 2011
Anti-fibrogenic Strategies and the regression of fibrosis
T Kisseleva, DA Brenner
Best practice & research. Clinical gastroenterology 2011
Epithelial-mesenchymal interactions in biliary diseases
L Fabris, M Strazzabosco
Seminars in liver disease 2011
Early growth response transcription factors: key mediators of fibrosis and novel targets for anti-fibrotic therapy
S Bhattacharyya, M Wu, F Fang, W Tourtellotte, C Feghali-Bostwick, J Varga
Matrix biology : journal of the International Society for Matrix Biology 2011
Epithelial-mesenchymal transition in breast cancer progression and metastasis
Y Wang, BP Zhou
Chinese journal of cancer 2011
[Epithelial-mesenchymal transition and tumor metastasis]
Rongzhi Zhao, Zhihao Wu, Qinghua Zhou
Zhongguo fei ai za zhi = Chinese journal of lung cancer 2011
An Evolutionary Explanation for the Perturbation of the Dynamics of Metastatic Tumors Induced by Surgery and Acute Inflammation
AC Bayonas
Cancers 2011
Cancer treatments transform residual cancer cell phenotype
WW Harless
Cancer Cell International 2011
Androgen regulation of epithelial-mesenchymal transition in prostate tumorigenesis
EA Matuszak, N Kyprianou
Expert Review of Endocrinology & Metabolism 2011
TGF-β regulates isoform switching of FGF receptors and epithelial-mesenchymal transition
T Shirakihara, K Horiguchi, K Miyazawa, S Ehata, T Shibata, I Morita, K Miyazono, M Saitoh
The EMBO Journal 2011
Regulation of Epithelial-Mesenchymal Transition by Transmission of Mechanical Stress through Epithelial Tissues
N Gjorevski, E Boghaert, CM Nelson
Cancer Microenvironment 2011
Evaluation of epithelial mesenchymal transition in patients with chronic obstructive pulmonary disease
SS Sohal, D Reid, A Soltani, C Ward, S Weston, HK Muller, R Wood-Baker, EH Walters
Respiratory Research 2011
The Role of Polymeric Immunoglobulin Receptor in Inflammation-Induced Tumor Metastasis of Human Hepatocellular Carcinoma
J Ai, Q Tang, Y Wu, Y Xu, T Feng, R Zhou, Y Chen, X Gao, Q Zhu, X Yue, Q Pan, S Xu, J Li, M Huang, J Daugherty-Holtrop, Y He, HE Xu, J Fan, J Ding, M Geng
JNCI Journal of the National Cancer Institute 2011
Tracking the intermediate stages of epithelial-mesenchymal transition in epithelial stem cells and cancer
NV Jordan, GL Johnson, AN Abell
Cell cycle (Georgetown, Tex.) 2011
Snail Involves in the Transforming Growth Factor β1-Mediated Epithelial-Mesenchymal Transition of Retinal Pigment Epithelial Cells
H Li, H Wang, F Wang, Q Gu, X Xu
PloS one 2011
Ribosomal protein S6 kinase (RSK)-2 as a central effector molecule in RON receptor tyrosine kinase mediated epithelial to mesenchymal transition induced by macrophage-stimulating protein
Q Ma, S Guin, SS Padhye, YQ Zhou, RW Zhang, MH Wang
Molecular Cancer 2011
Increase of α-SMA+ and CK+ Cells as an Early Sign of Epithelial-Mesenchymal Transition during Colorectal Carcinogenesis
G Valcz, F Sipos, T Krenács, J Molnár, ÁV Patai, K Leiszter, K Tóth, B Wichmann, B Molnár, Z Tulassay
Pathology & Oncology Research 2011
Cell dedifferentiation and epithelial to mesenchymal transitions during intestinal regeneration in H. glaberrima
JE García-Arrarás, G Valentín-Tirado, JE Flores, RJ Rosa, A Rivera-Cruz, JE san Miguel-Ruiz, K Tossas
BMC Developmental Biology 2011
Leukocytes as Paracrine Regulators of Metastasis and Determinants of Organ-Specific Colonization
N Erez, LM Coussens
International Journal of Cancer 2011
Substrate stiffness regulates extracellular matrix deposition by alveolar epithelial cells
JL Eisenberg, A Safi, X Wei, HD Espinosa, GS Budinger, D Takawira, SB Hopkinson, JC Jones
Research and Reports in Biology 2011
Diabetes Complications: The MicroRNA Perspective
P Kantharidis, B Wang, RM Carew, HY Lan
Diabetes 2011
Establishment of a highly migratory subclone reveals that CD133 contributes to migration and invasion through epithelial-mesenchymal transition in pancreatic cancer.
Ding Q, Yoshimitsu M, Kuwahata T, Maeda K, Hayashi T, Obara T, Miyazaki Y, Matsubara S, Natsugoe S, Takao S
Human Cell 2011
Androgen depletion induces senescence in prostate cancer cells through down-regulation of Skp2.
Pernicová Z, Slabáková E, Kharaishvili G, Bouchal J, Král M, Kunická Z, Machala M, Kozubík A, Souček K
Neoplasia (New York, N.Y.) 2011
Epithelial Notch Signaling Regulates Interstitial Fibrosis Development in Kidneys of Mice and Man
Bernhard Bielesz, Yasemin Sirin, Han Si, Thiruvur Niranjan, Antje Gruenwald, SeonHo Ahn, Hideki Kato, James Pullman, Manfred Gessler, Volker H. Haase, Katalin Susztak
Journal of Clinical Investigation 2010
miR-200a Prevents Renal Fibrogenesis Through Repression of TGF- 2 Expression
B Wang, P Koh, C Winbanks, MT Coughlan, A McClelland, A Watson, K Jandeleit-Dahm, WC Burns, MC Thomas, ME Cooper, P Kantharidis
Diabetes 2010
Epithelial–mesenchymal transition to be or not to be? Is the answer yes and no at the same time?
C Zhu, PR Mertens
International Urology and Nephrology 2010
Contribution of Epithelial Plasticity to Renal Transplantation–Associated Fibrosis
A Hertig, SN Flier, R Kalluri
Transplantation Proceedings 2010
Tissue transglutaminase promotes drug resistance and invasion by inducing mesenchymal transition in mammary epithelial cells
A Kumar, J Xu, S Brady, H Gao, D Yu, J Reuben, K Mehta
PloS one 2010
Cancer as a metabolic disease
TN Seyfried, LM Shelton
Nutrition & Metabolism 2010
TWIST1 promotes invasion through mesenchymal change in human glioblastoma
SA Mikheeva, AM Mikheev, A Petit, R Beyer, RG Oxford, L Khorasani, JP Maxwell, CA Glackin, H Wakimoto, I González-Herrero, I Sánchez-García, JR Silber, PJ Horner, RC Rostomily
Molecular Cancer 2010
Pathobiology of renal-specific oxidoreductase/myo-inositol oxygenase in diabetic nephropathy: its implications in tubulointerstitial fibrosis
P Xie, L Sun, PJ Oates, SK Srivastava, YS Kanwar
American journal of physiology. Renal physiology 2010
The tight junction associated signalling proteins ZO-1 and ZONAB regulate retinal pigment epithelium homeostasis in mice
A Georgiadis, M Tschernutter, JW Bainbridge, KS Balaggan, F Mowat, EL West, PM Munro, AJ Thrasher, K Matter, MS Balda, RR Ali
PloS one 2010
The existence of multipotent stem cells with epithelial-mesenchymal transition features in the human liver bud
J Su, P You, WL Li, XR Tao, HY Zhu, YC Yao, HY Yu, QW Han, B Yu, FX Liu, J Xu, JT Lau, YP Hu
The International Journal of Biochemistry & Cell Biology 2010
Integrated Proteomics and Genomics Analysis Reveals a Novel Mesenchymal to Epithelial Reverting Transition in Leiomyosarcoma through Regulation of Slug*
J Yang, JA Eddy, Y Pan, A Hategan, I Tabus, Y Wang, D Cogdell, ND Price, RE Pollock, AJ Lazar, KK Hunt, JC Trent, W Zhang
Molecular & cellular proteomics : MCP 2010
Pathological axes of wound repair: Gastrulation revisited
MA Aller, JI Arias, J Arias
Theoretical Biology and Medical Modelling 2010
Identification of a stem-like cell population by exposing metastatic breast cancer cell lines to repetitive cycles of hypoxia and reoxygenation
E Louie, S Nik, JS Chen, M Schmidt, B Song, C Pacson, XF Chen, S Park, J Ju, EI Chen
Breast Cancer Research 2010
Impact of mechanical unloading on microvasculature and associated central remodeling features of the failing human heart
SG Drakos, AG Kfoury, EH Hammond, BB Reid, MP Revelo, BY Rasmusson, KJ Whitehead, ME Salama, CH Selzman, J Stehlik, SE Clayson, MR Bristow, DG Renlund, DY Li
Journal of the American College of Cardiology 2010
Rac and Rho GTPases in cancer cell motility control
M Parri, P Chiarugi
Cell Communication and Signaling 2010
Epithelial mesenchymal transition and tumor budding in aggressive colorectal cancer: Tumor budding as oncotarget
Zlobec I, Lugli A
Oncotarget 2010
Signaling Mechanism(S) of Reactive Oxygen Species in Epithelial-Mesenchymal Transition Reminiscent of Cancer Stem Cells in Tumor Progression
Wang Z, Li Y, Sarkar FH
Current stem cell research & therapy 2010
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009
Fibrogenesis in kidney transplantation: potential targets for prevention and therapy
A Djamali, M Samaniego
Transplantation 2009
Epithelial-to-mesenchymal transitions in the liver
SS Choi, AM Diehl
Hepatology 2009
Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis
SS Choi, A Omenetti, RP Witek, CA Moylan, WK Syn, Y Jung, L Yang, DL Sudan, JK Sicklick, GA Michelotti, M Rojkind, AM Diehl
American journal of physiology. Gastrointestinal and liver physiology 2009

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