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Usage Information

A decade of molecular pathogenomic analysis of group A Streptococcus
James M. Musser, Samuel A. Shelburne III
James M. Musser, Samuel A. Shelburne III
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Review Series

A decade of molecular pathogenomic analysis of group A Streptococcus

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Abstract

Molecular pathogenomic analysis of the human bacterial pathogen group A Streptococcus has been conducted for a decade. Much has been learned as a consequence of the confluence of low-cost DNA sequencing, microarray technology, high-throughput proteomics, and enhanced bioinformatics. These technical advances, coupled with the availability of unique bacterial strain collections, have facilitated a systems biology investigative strategy designed to enhance and accelerate our understanding of disease processes. Here, we provide examples of the progress made by exploiting an integrated genome-wide research platform to gain new insight into molecular pathogenesis. The studies have provided many new avenues for basic and translational research.

Authors

James M. Musser, Samuel A. Shelburne III

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Usage data is cumulative from July 2025 through July 2026.

Usage JCI PMC
Text version 847 91
PDF 277 17
Figure 385 2
Table 74 0
Citation downloads 181 0
Totals 1,764 110
Total Views 1,874
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ISSN: 0021-9738 (print), 1558-8238 (online)

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