JCI - Citations to Confirming the RNAi-mediated mechanism of action of siRNA-based cancer therapeutics in mice

Citations to this article

Confirming the RNAi-mediated mechanism of action of siRNA-based cancer therapeutics in mice

Adam D. Judge, … , Kevin McClintock, Ian MacLachlan

Adam D. Judge, … , Kevin McClintock, Ian MacLachlan

Published February 23, 2009
Citation Information: J Clin Invest. 2009;119(3):661-673. https://doi.org/10.1172/JCI37515.

View: Text | PDF

Technical Advance

Total citations by year

Year:	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014	2013	2012	2011	2010	2009	Total
Citations:	1	3	6	4	5	6	2	5	5	7	5	10	19	8	12	9	5	112

Citation information

Citations to this article (112)

Title and authors	Publication	Year
A new paradigm for cancer immunotherapy: targeting immunogenic cell death-related noncoding RNA Sun G, He L	Frontiers in Immunology	2025
RNAi-based drug design: considerations and future directions. Tang Q, Khvorova A	Nature reviews. Drug discovery	2024
Selective Transfection of a Transferrin Receptor-Expressing Cell Line with DNA–Lipid Nanoparticles Vinales I, Silva-Espinoza JC, Medina BA, Urbay JE, Beltran MA, Salinas DE, Ramirez-Ramos MA, Maldonado RA, Poon W, Penichet ML, Almeida IC, Michael K	ACS Omega	2024
Development, opportunities, and challenges of siRNA nucleic acid drugs Xiao B, Wang S, Pan Y, Zhi W, Gu C, Guo T, Zhai J, Li C, Chen YQ, Wang R	Molecular Therapy. Nucleic Acids	2024
Structure and Function of Cationic and Ionizable Lipids for Nucleic Acid Delivery Sun D, Lu ZR	Pharmaceutical Research	2023
Oncolytic virus-based suicide gene therapy for cancer treatment: a perspective of the clinical trials conducted at Henry Ford Health Thoidingjam S, Sriramulu S, Freytag S, Brown SL, Kim JH, Chetty IJ, Siddiqui F, Movsas B, Nyati S	Translational Medicine Communications	2023
Innate immune regulations and various siRNA modalities. Kaushal A	Drug Delivery and Translational Research	2023
Advances in Pancreatic Cancer Treatment by Nano-Based Drug Delivery Systems Viegas C, Patrício AB, Prata J, Fonseca L, Macedo AS, Duarte SO, Fonte P	Pharmaceutics	2023
A holistic analysis of the intrinsic and delivery-mediated toxicity of siRNA therapeutics Ranjbar S, Zhong XB, Manautou J, Lu X	Advanced Drug Delivery Reviews	2023
A Comprehensive Review of Small Interfering RNAs (siRNAs): Mechanism, Therapeutic Targets, and Delivery Strategies for Cancer Therapy. Zhang J, Chen B, Gan C, Sun H, Zhang J, Feng L	International Journal of Nanomedicine	2023
Gene Therapy Using Nanocarriers for Pancreatic Ductal Adenocarcinoma: Applications and Challenges in Cancer Therapeutics E Won, H Park, T Yoon, Y Cho	Pharmaceutics	2022
Knockdown of 15-bp Deletion-Type v-raf Murine Sarcoma Viral Oncogene Homolog B1 mRNA in Pancreatic Ductal Adenocarcinoma Cells Repressed Cell Growth In Vitro and Tumor Volume In Vivo Song J, Kobayashi Y, Asano Y, Sato A, Taniguchi H, Ui-Tei K	Cancers	2022
siRNA‐based nanotherapeutics as emerging modalities for immune‐mediated diseases: A preliminary review Sargazi S, Arshad R, Ghamari R, Rahdar A, Bakhshi A, Karkan SF, Ajalli N, Bilal M, Díez\u2010Pascual AM	Cell biology international	2022
siRNA Functionalized Lipid Nanoparticles (LNPs) in Management of Diseases Kalita T, Dezfouli SA, Pandey LM, Uludag H	Pharmaceutics	2022
Extension in the approaches to treat cancer through siRNA system: a beacon of hope in cancer therapy I Rautela, A Sharma, P Dheer, P Thapliyal, S Sahni, VB Sinha, MD Sharma	Drug Delivery and Translational Research	2021
Irf5 siRNA-loaded biodegradable lipid nanoparticles ameliorate concanavalin A-induced liver injury W Kawase, D Kurotaki, Y Suzuki, H Ishihara, T Ban, GR Sato, J Ichikawa, H Yanai, T Taniguchi, K Tsukahara, T Tamura	Molecular Therapy — Nucleic Acids	2021
The Value of Circulating Circular RNA in Cancer Diagnosis, Monitoring, Prognosis, and Guiding Treatment Y Zhang, Y Wang, X Su, P Wang, W Lin	Frontiers in Oncology	2021
Recent Advances in the Delivery Carriers and Chemical Conjugation Strategies for Nucleic Acid Drugs S Oyama, T Yamamoto, A Yamayoshi	Cancers	2021
Cancer nanotechnology: current status and perspectives JA Kemp, YJ Kwon	Nano Convergence	2021
The Dual Role of the Liver in Nanomedicine as an Actor in the Elimination of Nanostructures or a Therapeutic Target L Baboci, S Capolla, FD Cintio, F Colombo, P Mauro, MD Bo, M Argenziano, R Cavalli, G Toffoli, P Macor	Journal of Oncology	2020
Small interfering RNA for cancer treatment: overcoming hurdles in delivery NB Charbe, ND Amnerkar, B Ramesh, MM Tambuwala, HA Bakshi, AA Aljabali, SC Khadse, R Satheeshkumar, S Satija, M Metha, DK Chellappan, G Shrivastava, G Gupta, P Negi, K Dua, FC Zacconi	Acta pharmaceutica Sinica. B	2020
Lipid-Based Drug Delivery Nanoplatforms for Colorectal Cancer Therapy C Yang, D Merlin	Nanomaterials	2020
Evolution of drug delivery system from viewpoint of controlled intracellular trafficking and selective tissue targeting toward future nanomedicine Y Yamada, Y Sato, T Nakamura, H Harashima	Journal of Controlled Release	2020
Silencing of VEGFR2 by RGD-Modified Lipid Nanoparticles Enhanced the Efficacy of Anti-PD-1 Antibody by Accelerating Vascular Normalization and Infiltration of T Cells in Tumors R Cho, Y Sakurai, HS Jones, H Akita, A Hisaka, H Hatakeyama	Cancers	2020
Lysosomal Storage Disease-Associated Neuropathy: Targeting Stable Nucleic Acid Lipid Particle (SNALP)-Formulated siRNAs to the Brain as a Therapeutic Approach MF Coutinho, JI Santos, LS Mendonça, L Matos, MJ Prata, AS Jurado, MC de Lima, S Alves	International journal of molecular sciences	2020
In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers S Watanabe, K Hayashi, K Toh, HJ Kim, X Liu, H Chaya, S Fukushima, K Katsushima, Y Kondo, S Uchida, S Ogura, T Nomoto, H Takemoto, H Cabral, H Kinoh, HY Tanaka, MR Kano, Y Matsumoto, H Fukuhara, S Uchida, M Nangaku, K Osada, N Nishiyama, K Miyata, K Kataoka	Nature Communications	2019
Rekindling RNAi Therapy: Materials Design Requirements for In Vivo siRNA Delivery B Kim, JH Park, MJ Sailor	Advanced materials (Deerfield Beach, Fla.)	2019
AMF siRNA treatment of keloid through inhibition signaling pathway of RhoA/ROCK1 Y Tian, L Jin, W Zhang, Z Ya, Y Cheng, H Zhao	Genes & Diseases	2018
High sensitivity and label-free oligonucleotides detection using photonic bandgap sensing structures biofunctionalized with molecular beacon probes Á Ruiz-Tórtola, F Prats-Quílez, D González-Lucas, MJ Bañuls, Á Maquieira, G Wheeler, T Dalmay, A Griol, J Hurtado, J García-Rupérez	Biomedical Optics Express	2018
Liposomal Delivery of miR-34b-5p Induced Cancer Cell Death in Thyroid Carcinoma H Maroof, F Islam, LF Dong, P Ajjikuttira, V Gopalan, N McMillan, A Lam	Cells	2018
An Open‐Label, Multicenter, Phase I, Dose Escalation Study with Phase II Expansion Cohort to Determine the Safety, Pharmacokinetics, and Preliminary Antitumor Activity of Intravenous TKM‐080301 in Subjects with Advanced Hepatocellular Carcinoma IE Dika, HY Lim, WP Yong, CC Lin, JH Yoon, M Modiano, B Freilich, HJ Choi, TY Chao, RK Kelley, J Brown, J Knox, BY Ryoo, T Yau, GK AbouAlfa	The oncologist	2018
Co-delivery of anti-PLK-1 siRNA and camptothecin by nanometric polydiacetylenic micelles results in a synergistic cell killing. Ripoll M, Pierdant M, Neuberg P, Bagnard D, Wagner A, Kichler A, Remy JS	RSC Advances	2018
Performance of Pyridylthiourea-Polyethylenimine Polyplex for siRNA-Mediated Liver Cancer Therapy in Cell Monolayer, Spheroid, and Tumor Xenograft Models JB Gossart, E Pascal, F Meyer, E Heuillard, M Gonçalves, F Gossé, E Robinet, B Frisch, C Seguin, G Zuber	Global Challenges	2017
Targeting MUC1 and JNK by RNA interference and inhibitor inhibit the development of hepatocellular carcinoma J Wang, W Ni, K Hu, X Zhai, F Xie, J Jie, N Zhang, L Jiang, H Yuan, G Tai	Cancer Science	2017
Stimuli-Responsive Mesoporous Silica NPs as Non-viral Dual siRNA/Chemotherapy Carriers for Triple Negative Breast Cancer B Darvishi, L Farahmand, K Majidzadeh-A	Molecular Therapy - Nucleic Acids	2017
Liposomal 64 Cu-PET Imaging of Anti-VEGF Drug Effects on Liposomal Delivery to Colon Cancer Xenografts SJ Blocker, KA Douglas, LA Polin, H Lee, BS Hendriks, E Lalo, W Chen, AF Shields	Theranostics	2017
Functionalized non-viral cationic vectors for effective siRNA induced cancer therapy Gupta K, Puri A, Shapiro BA		2017
Calcium phosphate nanoparticles-based systems for siRNA delivery X Xu, Z Li, X Zhao, L Keen, X Kong	Regenerative Biomaterials	2016
Lipid Nanoparticle-mediated siRNA Transfer Against PCTAIRE1/PCTK1/Cdk16 Inhibits In Vivo Cancer Growth T Yanagi, K Tachikawa, R Wilkie-Grantham, A Hishiki, K Nagai, E Toyonaga, P Chivukula, S Matsuzawa	Molecular Therapy — Nucleic Acids	2016
Lipid Nanovectors to Deliver RNA Oligonucleotides in Cancer V Campani, G Salzano, S Lusa, GD Rosa	Nanomaterials	2016
Mono-arginine Cholesterol-based Small Lipid Nanoparticles as a Systemic siRNA Delivery Platform for Effective Cancer Therapy J Lee, PE Saw, V Gujrati, Y Lee, H Kim, S Kang, M Choi, JI Kim, S Jon	Theranostics	2016
Remodeling of the Extracellular Matrix by Endothelial Cell-Targeting siRNA Improves the EPR-Based Delivery of 100 nm Particles Y Sakurai, T Hada, S Yamamoto, A Kato, W Mizumura, H Harashima	Molecular Therapy	2016
Targeting HPV-infected cervical cancer cells with PEGylated liposomes encapsulating siRNA and the role of siRNA complexation with polyethylenimine RM Levine, CV Dinh, MA Harris, E Kokkoli	Bioengineering & Translational Medicine	2016
Antibody targeting facilitates effective intratumoral siRNA nanoparticle delivery to HER2-overexpressing cancer cells. Palanca-Wessels MC, Booth GC, Convertine AJ, Lundy BB, Berguig GY, Press MF, Stayton PS, Press OW	Oncotarget	2016
Polymeric Nanostructures for Imaging and Therapy M Elsabahy, GS Heo, SM Lim, G Sun, KL Wooley	Chemical Reviews	2015
Knocking down disease: a progress report on siRNA therapeutics A Wittrup, J Lieberman	Nature Reviews Genetics	2015
RNA interference-based therapeutics for inherited long QT syndrome (Review) G Li, S Ma, C Sun	Experimental and therapeutic medicine	2015
Clinical experiences with systemically administered siRNA-based therapeutics in cancer JE Zuckerman, ME Davis	Nature Reviews Drug Discovery	2015
Short-interference RNAs: becoming medicines Tamara Martínez, Ana Isabel Jiménez, Covadonga Pañeda	EXCLI J	2015
Hepatic Monoacylglycerol O-acyltransferase 1 as a Promising Therapeutic Target for Steatosis, Obesity, and Type 2 Diabetes Y Hayashi, E Suemitsu, K Kajimoto, Y Sato, A Akhter, Y Sakurai, H Hatakeyama, M Hyodo, N Kaji, Y Baba, H Harashima	Molecular Therapy — Nucleic Acids	2014
Gene regulation by non-coding RNAs VS Patil, R Zhou, TM Rana	Critical Reviews in Biochemistry and Molecular Biology	2014
Silencing VDAC1 Expression by siRNA Inhibits Cancer Cell Proliferation and Tumor Growth In Vivo T Arif, L Vasilkovsky, Y Refaely, A Konson, V Shoshan-Barmatz	Molecular Therapy — Nucleic Acids	2014
In vivo activity of miR-34a mimics delivered by stable nucleic acid lipid particles (SNALPs) against multiple myeloma MT di Martino, V Campani, G Misso, ME Cantafio, A Gullà, U Foresta, PH Guzzi, M Castellano, A Grimaldi, V Gigantino, R Franco, S Lusa, M Cannataro, P Tagliaferri, GD Rosa, P Tassone, M Caraglia	PloS one	2014
Potential applications of nanotechnology for the diagnosis and treatment of pancreatic cancer J McCarroll, J Teo, C Boyer, D Goldstein, M Kavallaris, PA Phillips	Frontiers in physiology	2014
Antisense therapeutics in oncology: current status AA Farooqi, Z Marwat, J Muntane	OncoTargets and therapy	2014
Inhibition of Hepatitis C Virus in Chimeric Mice by Short Synthetic Hairpin RNAs: Sequence Analysis of Surviving Virus Shows Added Selective Pressure of Combination Therapy A Dallas, H Ilves, H Ma, DJ Chin, I MacLachlan, K Klumpp, BH Johnston	Journal of virology	2014
Antitumor Effects in Hepatocarcinoma of Isoform-Selective Inhibition of HDAC2 YH Lee, D Seo, KJ Choi, JB Andersen, MA Won, M Kitade, LE Gomez-Quiroz, AD Judge, JU Marquardt, C Raggi, EA Conner, I MacLachlan, VM Factor, SS Thorgeirsson	Cancer research	2014
Simultaneous silencing of VEGF and KSP by siRNA cocktail inhibits proliferation and induces apoptosis of hepatocellular carcinoma Hep3B cells C Doan, L Le, S Hoang, S Do, D Le	Biological research	2014
RNA interference and its role in cancer therapy Behzad Mansoori, Siamak Sandoghchian Shotorbani, Behzad Baradaran	Advanced pharmaceutical bulletin	2014
Aptamer-targeted inhibition of mTOR in T cells enhances antitumor immunity Alexey Berezhnoy, Iris Castro, Agata Levay, Thomas R. Malek, Eli Gilboa	Journal of Clinical Investigation	2013
RNAi Therapeutic Platforms for Lung Diseases Y Fujita, F Takeshita, K Kuwano, T Ochiya	Pharmaceuticals (Basel, Switzerland)	2013
MicroRNA 199b-5p delivery through stable nucleic acid lipid particles (SNALPs) in tumorigenic cell lines P Antonellis, L Liguori, A Falanga, M Carotenuto, V Ferrucci, I Andolfo, F Marinaro, I Scognamiglio, A Virgilio, G Rosa, A Galeone, S Galdiero, M Zollo	Naunyn-Schmiedeberg's Archives of Pharmacology	2013
Hyaluronic acid based self-assembling nanosystems for CD44 target mediated siRNA delivery to solid tumors S Ganesh, AK Iyer, DV Morrissey, MM Amiji	Biomaterials	2013
Gene silencing and antitumoral effects of Eg5 or Ran siRNA oligoaminoamide polyplexes D Edinger, R Kläger, C Troiber, C Dohmen, E Wagner	Drug Delivery and Translational Research	2013
An influenza virus-inspired polymer system for the timed release of siRNA NP Truong, W Gu, I Prasadam, Z Jia, R Crawford, Y Xiao, MJ Monteiro	Nature Communications	2013
Gene Silencing via RNAi and siRNA Quantification in Tumor Tissue Using MEND, a Liposomal siRNA Delivery System Y Sakurai, H Hatakeyama, Y Sato, M Hyodo, H Akita, H Harashima	Molecular Therapy	2013
Enhanced hepatic delivery of siRNA and microRNA using oleic acid based lipid nanoparticle formulations X Wang, B Yu, W Ren, X Mo, C Zhou, H He, HL Jia, L Wang, ST Jacob, RJ Lee, K Ghoshal, LJ Lee	Journal of Controlled Release	2013
Knockdown of β-catenin with Dicer-Substrate siRNAs Reduces Liver Tumor Burden In vivo H Dudek, DH Wong, R Arvan, A Shah, K Wortham, B Ying, R Diwanji, W Zhou, B Holmes, H Yang, WA Cyr, Y Zhou, A Shah, R Farkiwala, M Lee, Y Li, GR Rettig, MA Collingwood, SK Basu, MA Behlke, BD Brown	Molecular Therapy	2013
Challenging the future of siRNA therapeutics against cancer: the crucial role of nanotechnology LC Gomes-da-Silva, S Simões, JN Moreira	Cellular and Molecular Life Sciences	2013
Protection Against Lethal Marburg Virus Infection Mediated by Lipid Encapsulated Small Interfering RNA R Ursic-Bedoya, CE Mire, M Robbins, JB Geisbert, A Judge, I MacLachlan, TW Geisbert	The Journal of Infectious Diseases	2013
New aspects of gene-silencing for the treatment of cardiovascular diseases O Koenig, T Walker, N Perle, A Zech, B Neumann, C Schlensak, HP Wendel, A Nolte	Pharmaceuticals (Basel, Switzerland)	2013
Minimal-length Synthetic shRNAs Formulated with Lipid Nanoparticles are Potent Inhibitors of Hepatitis C Virus IRES-linked Gene Expression in Mice A Dallas, H Ilves, J Shorenstein, A Judge, R Spitler, C Contag, SP Wong, RP Harbottle, I Maclachlan, BH Johnston	Molecular Therapy — Nucleic Acids	2013
Recent developments in nanoparticle-based siRNA delivery for cancer therapy JM Lee, TJ Yoon, YS Cho	BioMed Research International	2013
Tumor-targeted Chlorotoxin-coupled Nanoparticles for Nucleic Acid Delivery to Glioblastoma Cells: A Promising System for Glioblastoma Treatment PM Costa, AL Cardoso, LS Mendonça, A Serani, C Custódia, M Conceição, S Simões, JN Moreira, LP de Almeida, MC de Lima	Molecular Therapy — Nucleic Acids	2013
Delivery of gene silencing agents for breast cancer therapy H Shen, V Mittal, M Ferrari, J Chang	Breast Cancer Research	2013
Cytokines as biomarkers of nanoparticle immunotoxicity M Elsabahy, KL Wooley	Chemical Society Reviews	2013
Technologies for investigating the physiological barriers to efficient lipid nanoparticle-siRNA delivery B Shi, M Abrams	The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society	2013
Efficient delivery of RNA interference oligonucleotides to polarized airway epithelia in vitro S Ramachandran, S Krishnamurthy, AM Jacobi, C Wohlford-Lenane, MA Behlke, BL Davidson, PB McCray	American journal of physiology. Lung cellular and molecular physiology	2013
Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells TI Novobrantseva, A Borodovsky, J Wong, B Klebanov, M Zafari, K Yucius, W Querbes, P Ge, VM Ruda, S Milstein, L Speciner, R Duncan, S Barros, G Basha, P Cullis, A Akinc, JS Donahoe, KN Jayaprakash, M Jayaraman, RL Bogorad, K Love, K Whitehead, C Levins, M Manoharan, FK Swirski, R Weissleder, R Langer, DG Anderson, A Fougerolles, M Nahrendorf, V Koteliansky	Molecular Therapy — Nucleic Acids	2012
The Business of RNAi Therapeutics in 2012 D Haussecker	Molecular Therapy — Nucleic Acids	2012
Ewing's Sarcoma: Development of RNA Interference-Based Therapy for Advanced Disease O Simmons, PB Maples, N Senzer, J Nemunaitis	ISRN Oncology	2012
Nanovector delivery of siRNA for cancer therapy H Shen, T Sun, M Ferrari	Cancer Gene Therapy	2012
Prospective of colon cancer treatments and scope for combinatorial approach to enhanced cancer cell apoptosis J Mishra, J Drummond, SH Quazi, SS Karanki, JJ Shaw, B Chen, N Kumar	Critical Reviews in Oncology/Hematology	2012
An RNA alternative to human transferrin: a new tool for targeting human cells SE Wilner, B Wengerter, K Maier, ML Magalhães, DS Amo, S Pai, F Opazo, SO Rizzoli, A Yan, M Levy	Molecular Therapy — Nucleic Acids	2012
Lipid nanoparticles for hepatic delivery of small interfering RNA B Yu, SH Hsu, C Zhou, X Wang, MC Terp, Y Wu, L Teng, Y Mao, F Wang, W Xue, ST Jacob, K Ghoshal, RJ Lee, LJ Lee	Biomaterials	2012
Novel lipoidal amine-based nanocarrier formulations for siRNA delivery. Zhou C, Yue Z, Lee LJ, Lee RJ	Therapeutic Delivery	2012
Therapeutic siRNA silencing in inflammatory monocytes F Leuschner, P Dutta, R Gorbatov, TI Novobrantseva, JS Donahoe, G Courties, KM Lee, JI Kim, JF Markmann, B Marinelli, P Panizzi, WW Lee, Y Iwamoto, S Milstein, H Epstein-Barash, W Cantley, J Wong, V Cortez-Retamozo, A Newton, K Love, P Libby, MJ Pittet, FK Swirski, V Koteliansky, R Langer, R Weissleder, DG Anderson, M Nahrendorf	Nature Biotechnology	2011
RNA interference against polo-like kinase-1 in advanced non-small cell lung cancers E Kawata, E Ashihara, T Maekawa	Journal of Clinical Bioinformatics	2011
Gene silencing by siRNAs and antisense oligonucleotides in the laboratory and the clinic JK Watts, DR Corey	The Journal of Pathology	2011
Molecular targeting of CSN5 in human hepatocellular carcinoma: a mechanism of therapeutic response YH Lee, AD Judge, D Seo, M Kitade, LE Gómez-Quiroz, T Ishikawa, JB Andersen, BK Kim, JU Marquardt, C Raggi, I Avital, EA Conner, I MacLachlan, VM Factor, SS Thorgeirsson	Oncogene	2011
Using drug-excipient interactions for siRNA delivery K Bruno	Advanced Drug Delivery Reviews	2011
Tumor vasculature is a key determinant for the efficiency of nanoparticle-mediated siRNA delivery L Li, R Wang, D Wilcox, X Zhao, J Song, X Lin, WM Kohlbrenner, SW Fesik, Y Shen	Gene Therapy	2011
Octa-functional PLGA nanoparticles for targeted and efficient siRNA delivery to tumors J Zhou, TR Patel, M Fu, JP Bertram, WM Saltzman	Biomaterials	2011
Calcium phosphate nanoparticles with an asymmetric lipid bilayer coating for siRNA delivery to the tumor J Li, Y Yang, L Huang	Journal of Controlled Release	2011
SPANosomes as delivery vehicles for small interfering RNA (siRNA) C Zhou, Y Mao, Y Sugimoto, Y Zhang, N Kanthamneni, B Yu, RW Brueggemeier, LJ Lee, RJ Lee	Molecular Pharmaceutics	2011
Progress Toward In Vivo Use of siRNAs-II GR Rettig, MA Behlke	Molecular Therapy	2011
Multi-modal strategies for overcoming tumor drug resistance: hypoxia, the Warburg effect, stem cells, and multifunctional nanotechnology L Milane, S Ganesh, S Shah, ZF Duan, M Amiji	Journal of Controlled Release	2011
Current prospects for RNA interference-based therapies BL Davidson, PB McCray	Nature Reviews Genetics	2011
Cancer biomarker discovery: the entropic hallmark R Berretta, P Moscato	PloS one	2010
Clinical status of duplex RNA JK Watts, DR Corey	Bioorganic & Medicinal Chemistry Letters	2010
A status report on RNAi therapeutics AK Vaishnaw, J Gollob, C Gamba-Vitalo, R Hutabarat, D Sah, R Meyers, T Fougerolles, J Maraganore	Silence	2010
Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy K Strebhardt	Nature Reviews Drug Discovery	2010
Knockdown of FcγRIII in an arthritic temporomandibular joint reduced the nociceptive response PR Kramer, J Puri, LL Bellinger	Arthritis & Rheumatism	2010
Definition of ubiquitination modulator COP1 as a novel therapeutic target in human hepatocellular carcinoma YH Lee, JB Andersen, HT Song, AD Judge, D Seo, T Ishikawa, JU Marquardt, M Kitade, ME Durkin, C Raggi, HG Woo, EA Conner, I Avital, I Maclachlan, VM Factor, SS Thorgeirsson	Cancer research	2010
Lipid-based nanotherapeutics for siRNA delivery: Symposium: Lipid-based siRNA nanotherapeutics A Schroeder, CG Levins, C Cortez, R Langer, DG Anderson	Journal of Internal Medicine	2010
Postexposure protection of non-human primates against a lethal Ebola virus challenge with RNA interference: a proof-of-concept study TW Geisbert, AC Lee, M Robbins, JB Geisbert, AN Honko, V Sood, JC Johnson, S de Jong, I Tavakoli, A Judge, LE Hensley, I MacLachlan	Lancet	2010
Rational design of cationic lipids for siRNA delivery SC Semple, A Akinc, J Chen, AP Sandhu, BL Mui, CK Cho, DW Sah, D Stebbing, EJ Crosley, E Yaworski, IM Hafez, JR Dorkin, J Qin, K Lam, KG Rajeev, KF Wong, LB Jeffs, L Nechev, ML Eisenhardt, M Jayaraman, M Kazem, MA Maier, M Srinivasulu, MJ Weinstein, Q Chen, R Alvarez, SA Barros, S De, SK Klimuk, T Borland, V Kosovrasti, WL Cantley, YK Tam, M Manoharan, MA Ciufolini, MA Tracy, A de Fougerolles, I MacLachlan, PR Cullis, TD Madden, MJ Hope	Nature Biotechnology	2010
Gene silencing below the immune radar Gunther Hartmann	Journal of Clinical Investigation	2009
Lipidic systems for in vivo siRNA delivery SY Wu, NA McMillan	The AAPS Journal	2009
A rapid and sensitive method to detect siRNA-mediated mRNA cleavage in vivo using 5' RACE and a molecular beacon probe A Lasham, M Herbert, NC Wallant, R Patel, S Feng, M Eszes, H Cao, G Reid	Nucleic Acids Research	2009
Sequence-non-specific effects of RNA interference triggers and microRNA regulators M Olejniczak, P Galka, WJ Krzyzosiak	Nucleic Acids Research	2009
Silencing prostate cancer I Toudjarska, A de Fougerolles	Nature Biotechnology	2009

Advertisement