Following injury, the clearance of apoptotic and necrotic cells is necessary for mitigation and resolution of inflammation and tissue repair. In addition to macrophages, which are traditionally assigned to this task, neighboring epithelial cells in the affected tissue are postulated to contribute to this process. Kidney injury molecule–1 (KIM-1 or TIM-1) is an immunoglobulin superfamily cell-surface protein not expressed by cells of the myeloid lineage but highly upregulated on the surface of injured kidney epithelial cells. Here we demonstrate that injured kidney epithelial cells assumed attributes of endogenous phagocytes. Confocal images confirm internalization of apoptotic bodies within KIM-1–expressing epithelial cells after injury in rat kidney tubules in vivo. KIM-1 was directly responsible for phagocytosis in cultured primary rat tubule epithelial cells and also porcine and canine epithelial cell lines. KIM-1 was able to specifically recognize apoptotic cell surface-specific epitopes phosphatidylserine, and oxidized lipoproteins, expressed by apoptotic tubular epithelial cells. Thus, KIM-1 is the first nonmyeloid phosphatidylserine receptor identified to our knowledge that transforms epithelial cells into semiprofessional phagocytes.
Takaharu Ichimura, Edwin J.P.v. Asseldonk, Benjamin D. Humphreys, Lakshman Gunaratnam, Jeremy S. Duffield, Joseph V. Bonventre
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The role of IGFBP-1 in the clinical prognosis and pathophysiology of acute kidney injury
Joseph Holthoff, Nithin Karakala, AG Basnakian, Ricky Edmondson, Todd Fite, Neriman Gokden, Yanping Harville, Christian Herzog, Kaegan Holthoff, Luis Juncos, Alena Savenka, Randall Shelton, John Arthur |
American journal of physiology. Renal physiology | 2025 |
A Newly Identified Protective Role of C5a Receptor 1 in Kidney Tubules against Toxin-Induced Acute Kidney Injury
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The American Journal of Pathology | 2025 |
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Nature Communications | 2025 |
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2024 | |
The Role of TIM-1 and CD300a in Zika Virus Infection Investigated with Cell-Based Electrical Impedance
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International journal of molecular medicine | 2024 |
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International journal of molecular sciences | 2024 |
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Chicano Wust I |
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International journal of molecular sciences | 2023 |
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Clinical Kidney Journal | 2023 |
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Toxicological sciences : an official journal of the Society of Toxicology | 2023 |
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Viral interactions with host factors (TIM-1, TAM -receptors, Glut-1) are related to the disruption of glucose and ascorbate transport and homeostasis, causing the haemorrhagic manifestations of viral haemorrhagic fevers.
Chicano Wust I |
F1000Research | 2023 |
Sex differences in resilience to ferroptosis underlie sexual dimorphism in kidney injury and repair
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Cell Reports | 2022 |
Before the “cytokine storm”: Boosting efferocytosis as an effective strategy against SARS-CoV-2 infection and associated complications
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SUBCLINICAL KIDNEY INJURY IS CAUSED BY A MODERATE SINGLE INFLAMMATORY EVENT.
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A 3-Mbp fragment on rat chromosome 1 affects susceptibility both to stroke and kidney injury under salt loading in the stroke-prone spontaneously hypertensive rat: a genetic approach using multiple congenic strains.
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Experimental Animals | 2022 |
Heat acclimation ameliorated heat stress-induced acute kidney injury and prevented changes in kidney macrophages and fibrosis
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AJP Renal Physiology | 2022 |
Autophagy in renal fibrosis: Protection or promotion?
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Schelling JR |
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BMC veterinary research | 2022 |
Redox phospholipidomics analysis reveals specific oxidized phospholipids and regions in the diabetic mouse kidney.
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Redox Biology | 2022 |
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Vorselen D |
Biochemical Society Transactions | 2022 |
Most Arginase-1 Positive Cells Are Likely Injured S3 Proximal Tubular Cells Carrying Upregulated Phagocytotic Capacity rather than M2 Macrophages—Too Many To Be True
Zhang PL, Blatt NB, Kanaan HD, Wickman LT |
Journal of the American Society of Nephrology : JASN | 2022 |
Chimeric efferocytic receptors improve apoptotic cell clearance and alleviate inflammation
Morioka S, Kajioka D, Yamaoka Y, Ellison RM, Tufan T, Werkman IL, Tanaka S, Barron B, T Ito S, Kucenas S, Okusa MD, Ravichandran KS |
Cell | 2022 |
KIM-1 augments hypoxia-induced tubulointerstitial inflammation through uptake of small extracellular vesicles by tubular epithelial cells
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Molecular Therapy | 2022 |
Nephroprotective activity of naringin against chemical-induced toxicity and renal ischemia/reperfusion injury: A review
Amini N, Maleki M, Badavi M |
Avicenna journal of phytomedicine | 2022 |
Hydroxychloroquine Inhibits Macrophage Activation and Attenuates Renal Fibrosis After Ischemia-Reperfusion Injury
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Frontiers in immunology | 2021 |
KIM-1-mediated anti-inflammatory activity is preserved by MUC1 induction in the proximal tubule during ischemia-reperfusion injury
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American journal of physiology. Renal physiology | 2021 |
Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair
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eLife | 2021 |
HDAC2 targeting stabilizes the CoREST complex in renal tubular cells and protects against renal ischemia/reperfusion injury
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Scientific Reports | 2021 |
Shroom3, a Gene Associated with CKD, Modulates Epithelial Recovery after AKI
A Li, J Cunanan, H Khalili, T Plageman, K Ask, A Khan, A Hunjan, T Drysdale, D Bridgewater |
2021 | |
Translational Urinomics
HM dos Santos |
2021 | |
Cilomilast Ameliorates Renal Tubulointerstitial Fibrosis by Inhibiting the TGF-β1-Smad2/3 Signaling Pathway
M Xu, S Li, J Wang, S Huang, A Zhang, Y Zhang, W Gu, X Yu, Z Jia |
Frontiers in Medicine | 2021 |
Extracellular vesicles mediate cellular interactions in renal diseases—Novel views of intercellular communications in the kidney
PL Zhang, ML Liu |
Journal of Cellular Physiology | 2021 |
The Assessment of the Usefulness of Selected Markers in the Diagnosis of Chronic Kidney Disease in Children
A Będzichowska, K Jobs, M Kloc, A Bujnowska, B Kalicki |
Biomarker insights | 2021 |
Tim-1 Deficiency Aggravates High-Fat Diet-Induced Steatohepatitis in Mice
J George, Y Zhang, J Sloan, JM Sims, JD Imig, X Zhao |
Frontiers in immunology | 2021 |
Novel Roles of the Tim Family in Immune Regulation and Autoimmune Diseases
Y Liu, H Chen, Z Chen, J Qiu, H Pang, Z Zhou |
Frontiers in immunology | 2021 |
Kidney Injury Molecule 1 (KIM-1): a Multifunctional Glycoprotein and Biological Marker (Review)
TA Karmakova, NS Sergeeva, KY Kanukoev, BY Alekseev, AD Kaprin |
2021 | |
KIM-1 mediates fatty acid uptake by renal tubular cells to promote progressive diabetic kidney disease
Y Mori, AK Ajay, JH Chang, S Mou, H Zhao, S Kishi, J Li, CR Brooks, S Xiao, HM Woo, VS Sabbisetti, SC Palmer, P Galichon, L Li, JM Henderson, VK Kuchroo, J Hawkins, T Ichimura, JV Bonventre |
Cell Metabolism | 2021 |
Having an Old Friend for Dinner: The Interplay between Apoptotic Cells and Efferocytes
AL Lam, B Heit |
Cells | 2021 |
A Review of Specific Biomarkers of Chronic Renal Injury and Their Potential Application in Nonclinical Safety Assessment Studies
LA Obert, SA Elmore, D Ennulat, KS Frazier |
Toxicologic pathology | 2021 |
Glycemic Variability and KIM-1–Induced Inflammation in the Diabetic Kidney
KR Tuttle, RZ Alicic |
Diabetes | 2021 |
Kidney injury molecule-1 inhibits metastasis of renal cell carcinoma
JC Lee, DM Yotis, JY Lee, MA Sarabusky, B Shrum, A Champagne, OZ Ismail, E Tutunea-Fatan, HS Leong, L Gunaratnam |
Scientific Reports | 2021 |
Renal Protective Effect of Beluga Lentil Pretreatment for Ischemia-Reperfusion Injury
S Lee, SY Chun, EH Lee, B Kim, BH Yoon, H Gil, DH Kim, BI Jang, DW Lee, ES Yoo, DJ Park, JN Lee, MH Han, BS Kim, PH Song, TG Kwon, YS Ha, D Monlezun |
BioMed Research International | 2021 |
Effect of embedded metal fragments on urinary metal levels and kidney biomarkers in the Sprague-Dawley rat
JF Hoffman, VB Vergara, AX Fan, JF Kalinich |
Toxicology Reports | 2021 |
Environmental circadian disruption suppresses rhythms in kidney function and accelerates excretion of renal injury markers in urine of male hypertensive rats
AM Hill, GR Crislip, A Stowie, I Ellis, A Ramsey, O Castanon-Cervantes, ML Gumz, AJ Davidson |
American journal of physiology. Renal physiology | 2021 |
Conceptual advances and evolving terminology in acute kidney disease
JA Kellum, C Ronco, R Bellomo |
Nature Reviews Nephrology | 2021 |
Anaesthesia-Induced Transcriptomic Changes in the Context of Renal Ischemia Uncovered by the Use of a Novel Clamping Device
C Verney, D Legouis, S Placier, T Migeon, P Bonnin, D Buob, J Hadchouel, P Galichon |
International journal of molecular sciences | 2021 |
Nephrotoxicity Assessment with Human Kidney Tubuloids using Spherical Nucleic Acid-Based mRNA Nanoflares
C Wiraja, Y Mori, T Ichimura, J Hwang, C Xu, JV Bonventre |
Nano letters | 2021 |
Abnormal development of cerebral arteries and veins in offspring of experimentally preeclamptic rats: Potential role in perinatal stroke
EE Whitaker, AC Johnson, JE Miller, DP Lindner, MJ Cipolla |
Mechanisms of Ageing and Development | 2021 |
Recombinant apoptosis inhibitor of macrophage protein reduces delayed graft function in a murine model of kidney transplantation
JY Lee, S Arumugarajah, D Lian, N Maehara, AR Haig, RS Suri, T Miyazaki, L Gunaratnam, P Mukhopadhyay |
PloS one | 2021 |
The Phosphatidylserine Receptor TIM-1 Enhances Authentic Chikungunya Virus Cell Entry
J Kirui, Y Abidine, A Lenman, K Islam, YD Gwon, L Lasswitz, M Evander, M Bally, G Gerold |
Cells | 2021 |
Selective depletion of a CD64-expressing phagocyte subset mediates protection against toxic kidney injury and failure
N Salei, X Ji, D Pakalniškytė, V Kuentzel, S Rambichler, N Li, M Moser, K Steiger, T Buch, HJ Anders, BU Schraml |
Proceedings of the National Academy of Sciences | 2021 |
Depletion of Toll-Like Receptor-9 Attenuates Renal Tubulointerstitial Fibrosis After Ischemia-Reperfusion Injury
H Zheng, Y Zhang, L Li, R Zhang, Z Luo, Z Yang, Y Ye, J He, Q Sun |
Frontiers in Cell and Developmental Biology | 2021 |
The Nephroprotective Properties of Extracellular Vesicles in Experimental Models of Chronic Kidney Disease: a Systematic Review
N Nowak, M Yamanouchi, E Satake |
Stem Cell Reviews and Reports | 2021 |
Approaches for Controlling Antibody-Mediated Allograft Rejection Through Targeting B Cells
Y Matsuda, T Watanabe, XK Li |
Frontiers in immunology | 2021 |
Kidney injury molecule-1: a novel entry factor for SARS-CoV-2
C Wan, C Zhang |
Journal of Molecular Cell Biology | 2021 |
Positive correlation between renal tubular flattening and renal tubular injury/interstitial fibrosis in murine kidney disease models
Y TAKAHASHI, M WATANABE, K HIURA, A ISOBE, H SASAKI, N SASAKI |
Journal of Veterinary Medical Science | 2021 |
CD36 Ectodomain Detects Apoptosis in Mammalian Cells
S Banesh, V Trivedi |
Molecular Biotechnology | 2021 |
Conserved and Distinct Elements of Phagocytosis in Human and C. elegans
S Lukácsi, Z Farkas, É Saskői, Z Bajtay, K Takács-Vellai |
International journal of molecular sciences | 2021 |
EphA2 Interacts with Tim-4 through Association between Its FN3 Domain and the IgV Domain of Tim-4
B Moon, S Yang, K Kim, J Lee, D Jeong, D Park |
Cells | 2021 |
Kidney Injury Molecule-1 and Periostin Urinary Excretion and Tissue Expression Levels and Association with Glomerular Disease Outcomes
Q Wu, JP Troost, T Dai, C Nast, S Eddy, B Wei, Y Wang, DS Gipson, KM Dell, KL Gibson, M Kretzler, S Adler |
2021 | |
Pairwise effects between lipid GWAS genes modulate lipid plasma levels and cellular uptake
M Zimoń, Y Huang, A Trasta, A Halavatyi, JZ Liu, CY Chen, P Blattmann, B Klaus, CD Whelan, D Sexton, S John, W Huber, EA Tsai, R Pepperkok, H Runz |
Nature Communications | 2021 |
Kidney injury molecule‑1 levels are associated with therapeutic outcomes and renal tubulointerstitial injury severity in idiopathic membranous nephropathy
Y Zhang, C Xiang, L Gong, Y Zhang, J Zhen, Z Hu, X Xiao |
Experimental and therapeutic medicine | 2021 |
High-Fat Diet-Induced Renal Proximal Tubular Inflammatory Injury: Emerging Risk Factor of Chronic Kidney Disease
S Chen, J Chen, S Li, F Guo, A Li, H Wu, J Chen, Q Pan, S Liao, H Liu, Q Pan |
Frontiers in physiology | 2021 |
Sweeping up dying cells during tissue injury
Arai Y, Yamaoka Y, Morioka S |
Nephron | 2021 |
Metabolic Consequences of Efferocytosis and its Impact on Atherosclerosis.
Yurdagul A Jr |
Immunometabolism | 2021 |
Human kidney injury molecule-1 as a urine biomarker differentiating urothelial and renal cell carcinoma
Białek Ł, Niemczyk M, Czerwińska K, Nowak M, Sadowska A, Borkowski T, Radziszewski P, Dobruch J, Kryst P, Poletajew S |
Central European Journal of Urology | 2021 |
Immunopathophysiology of trauma-related acute kidney injury
DA Messerer, R Halbgebauer, B Nilsson, H Pavenstädt, P Radermacher, M Huber-Lang |
Nature Reviews Nephrology | 2020 |
Protective Effects of Recombinant Human Soluble Thrombomodulin on Lipopolysaccharide-Induced Acute Kidney Injury
Y Nozaki, J Ri, K Sakai, K Niki, M Funauchi, I Matsumura |
International journal of molecular sciences | 2020 |
The Yin and Yang of Alarmins in Regulation of Acute Kidney Injury
V Sabapathy, R Venkatadri, M Dogan, R Sharma |
Frontiers in Medicine | 2020 |
Sodium Oxalate-Induced Acute Kidney Injury Associated With Glomerular and Tubulointerstitial Damage in Rats
L de Araújo, JM Costa-Pessoa, MC de Ponte, M Oliveira-Souza |
Frontiers in physiology | 2020 |
The role of phosphatidylserine recognition receptors in multiple biological functions
MB Naeini, V Bianconi, M Pirro, A Sahebkar |
Cellular & Molecular Biology Letters | 2020 |
Acute kidney injury and maladaptive tubular repair leading to renal fibrosis:
SM Yu, JV Bonventre |
Current Opinion in Nephrology and Hypertension | 2020 |
The Network of Inflammatory Mechanisms in Lupus Nephritis
Y Nozaki |
Frontiers in Medicine | 2020 |
Role of tumor cell senescence in non-professional phagocytosis and cell-in-cell structure formation
D Gottwald, F Putz, N Hohmann, M Büttner-Herold, M Hecht, R Fietkau, L Distel |
2020 | |
Nephrotoxicity of Herbal Medicine and Its Prevention
X Xu, R Zhu, J Ying, M Zhao, X Wu, G Cao, K Wang |
Frontiers in pharmacology | 2020 |
Phosphatidylethanolamine and Phosphatidylserine Synergize To Enhance GAS6/AXL-Mediated Virus Infection and Efferocytosis
L Zhang, AS Richard, CB Jackson, A Ojha, H Choe, RE Dutch |
Journal of virology | 2020 |
Predictive Nephrotoxicity Profiling of a Novel Antifungal Small Molecule in Comparison to Amphotericin B and Voriconazole
NS Udawatte, SW Kang, Y Wang, TV Arumugam, CJ Seneviratne |
Frontiers in pharmacology | 2020 |
Tim-4 functions as a scavenger receptor for phagocytosis of exogenous particles
C Min, J Park, G Kim, H Moon, SA Lee, D Kim, B Moon, S Yang, J Lee, K Kim, H Cho, J Park, DH Lee, G Lee, D Park |
Cell Death and Disease | 2020 |
Mapping and functional characterization of murine kidney injury molecule-1 proteolytic cleavage site
S Sriranganathan, E Tutunea-Fatan, A Abbasi, L Gunaratnam |
Molecular and Cellular Biochemistry | 2020 |
ROS-responsive chitosan-SS31 prodrug for AKI therapy via rapid distribution in the kidney and long-term retention in the renal tubule
D Liu, G Shu, F Jin, J Qi, X Xu, Y Du, H Yu, J Wang, M Sun, Y You, M Zhu, M Chen, L Zhu, Q Shen, X Ying, X Lou, S Jiang, Y Du |
Science Advances | 2020 |
Ethyl acetate extract of Ceiba pentandra (L.) Gaertn. reduces methotrexate-induced renal damage in rats via antioxidant, anti-inflammatory, and antiapoptotic actions
ME Abouelela, MA Orabi, RA Abdelhamid, MS Abdelkader, HR Madkor, FM Darwish, T Hatano, BE Elsadek |
Journal of traditional and complementary medicine | 2020 |
Dexmedetomidine Enhances Autophagy via α2-AR/AMPK/mTOR Pathway to Inhibit the Activation of NLRP3 Inflammasome and Subsequently Alleviates Lipopolysaccharide-Induced Acute Kidney Injury
T Yang, X Feng, Y Zhao, H Zhang, H Cui, M Wei, H Yang, H Fan |
Frontiers in pharmacology | 2020 |
Curcumin alleviates acute kidney injury in a dry‐heat environment by reducing oxidative stress and inflammation in a rat model
YH Zhao, CF Shen, GJ Wang, Y Kang, YH Song, JW Liu |
Journal of Biochemical and Molecular Toxicology | 2020 |
The Predictive Value of Urinary Kidney Injury Molecular 1 for the Diagnosis of Contrast-Induced Acute Kidney Injury after Cardiac Catheterization: A Meta-Analysis
Q Li, Y Huang, W Shang, Y Zhang, Y Liu, G Xu |
Journal of Interventional Cardiology | 2020 |
Novel renal biomarkers show that creatine supplementation is safe: a double-blind, placebo-controlled randomized clinical trial
J de Oliveira Vilar Neto, CA da Silva, GC Meneses, DV Pinto, LC Brito, SG da Cruz Fonseca, R de Sousa Alves, AM Martins, C de Oliveira Assumpção, ED Daher |
Toxicology Research | 2020 |
A review of the application of nanoparticles in the diagnosis and treatment of chronic kidney disease
Y Ma, F Cai, Y Li, J Chen, F Han, W Lin |
Bioactive Materials | 2020 |
Roles Played by Biomarkers of Kidney Injury in Patients with Upper Urinary Tract Obstruction
S Washino, K Hosohata, T Miyagawa |
International journal of molecular sciences | 2020 |
Effects of pneumoperitoneum with carbon dioxide on renal and hepatic functions in rats
T Bilgic, F Narter |
VIDEOSURGERY MINIINV | 2020 |
Proximal tubule ATR regulates DNA repair to prevent maladaptive renal injury responses
Seiji Kishi, Craig R. Brooks, Kensei Taguchi, Takaharu Ichimura, Yutaro Mori, Akinwande Akinfolarin, Navin Gupta, Pierre Galichon, Bertha C Elias, Tomohisa Suzuki, Qian Wang, Leslie Gewin, Ryuji Morizane, Joseph V. Bonventre |
Journal of Clinical Investigation | 2019 |
FoxM1 drives proximal tubule proliferation during repair from acute ischemic kidney injury
Monica Chang-Panesso, Farid F Kadyrov, Matthew, A Lalli, Haojia Wu, Shiyo Ikeda, Eirini Kefaloyianni, Mai M. Abdelmageed, Andreas Herrlich, Akio Kobayashi, Benjamin D. Humphreys |
Journal of Clinical Investigation | 2019 |
MicroRNA-146a-deficient mice develop immune complex glomerulonephritis
L Amrouche, S You, V Sauvaget, V Manda, B Lamarthée, G Desbuissons, C Tinel, M Rabant, C Nguyen, P Isnard, M Burtin, N Charles, C Legendre, F Terzi, D Anglicheau |
Scientific Reports | 2019 |
Efferocytosis in health and disease
AC Doran, A Yurdagul, I Tabas |
Nature Reviews Immunology | 2019 |
Why Have Detection, Understanding and Management of Kidney Hypoxic Injury Lagged Behind those for the Heart?
Z Abassi, S Rosen, S Lamothe, SN Heyman |
Journal of Clinical Medicine | 2019 |
Biomarkers of Drug-Induced Kidney Toxicity:
BR Griffin, S Faubel, CL Edelstein |
Therapeutic Drug Monitoring | 2019 |
TIM-3 and TIM-1 Could Regulate Decidual γδ TCR Bright T Cells during Murine Pregnancy
J Nörenberg, M Meggyes, P Jakso, E Miko, A Barakonyi |
Journal of Immunology Research | 2019 |
Gentamicin induced acute renal damage and its evaluation using urinary biomarkers in rats
V Udupa, V Prakash |
Toxicology Reports | 2019 |
Characterization of the Filovirus-Resistant Cell Line SH-SY5Y Reveals Redundant Role of Cell Surface Entry Factors
F Zapatero-Belinchón, E Dietzel, O Dolnik, K Döhner, R Costa, B Hertel, B Veselkova, J Kirui, A Klintworth, M Manns, S Pöhlmann, T Pietschmann, T Krey, S Ciesek, G Gerold, B Sodeik, S Becker, T von Hahn |
Viruses | 2019 |
Nifedipine Modulates Renal Lipogenesis via the AMPK-SREBP Transcriptional Pathway
YC Lin, MS Wu, YF Lin, CR Chen, CY Chen, CJ Chen, CC Shen, KC Chen, CC Peng |
International journal of molecular sciences | 2019 |
Kidney injury molecule-1 expression predicts structural damage and outcome in histological acute tubular injury
J Cai, X Jiao, W Luo, J Chen, X Xu, Y Fang, X Ding, X Yu |
Renal Failure | 2019 |
In Vivo Comparison of the Phenotypic Aspects and Molecular Mechanisms of Two Nephrotoxic Agents, Sodium Fluoride and Uranyl Nitrate
A Bontemps, L Conquet, C Elie, V Magneron, C Gloaguen, D Kereselidze, K Tack, O Barbier, Y Guéguen |
International journal of environmental research and public health | 2019 |
Translational Assessment of Drug‐Induced Proximal Tubule Injury Using a Kidney Microphysiological System
C Maass, NB Sorensen, J Himmelfarb, EJ Kelly, CL Stokes, M Cirit |
CPT Pharmacometrics Syst. Pharmacol. | 2019 |
Evaluation of kidney injury molecule-1 as a disease progression biomarker in diabetic nephropathy
FA Khan, SS Fatima, GM Khan, S Shahid |
Pakistan Journal of Medical Sciences | 2019 |
TIM-1 serves as a receptor for Ebola virus in vivo, enhancing viremia and pathogenesis
B Brunton, K Rogers, EK Phillips, RB Brouillette, R Bouls, NS Butler, W Maury, MR Holbrook |
PLoS neglected tropical diseases | 2019 |
Non-professional phagocytosis: a general feature of normal tissue cells
JC Seeberg, M Loibl, F Moser, M Schwegler, M Büttner-Herold, C Daniel, FB Engel, A Hartmann, U Schlötzer-Schrehardt, M Goppelt-Struebe, V Schellerer, E Naschberger, I Ganzleben, L Heinzerling, R Fietkau, LV Distel |
Scientific Reports | 2019 |
Kidney Injury Molecule-1 Is Upregulated in Renal Lipotoxicity and Mediates Palmitate-Induced Tubular Cell Injury and Inflammatory Response
X Zhao, X Chen, Y Zhang, J George, A Cobbs, G Wang, L Li, N Emmett |
International journal of molecular sciences | 2019 |
Zika Virus Infection Induces Acute Kidney Injury Through Activating NLRP3 Inflammasome Via Suppressing Bcl-2
T Liu, L Tang, H Tang, J Pu, S Gong, D Fang, H Zhang, YP Li, X Zhu, W Wang, M Wu, Y Liao, C Li, H Zhou, |
Frontiers in immunology | 2019 |
Renovascular disease induces mitochondrial damage in swine scattered tubular cells
AA Nargesi, XY Zhu, SM Conley, JR Woollard, IM Saadiq, LO Lerman, A Eirin |
American journal of physiology. Renal physiology | 2019 |
Neonatal obstructive nephropathy induces necroptosis and necroinflammation
B Popper, MT Rammer, M Gasparitsch, T Singer, U Keller, Y Döring, B Lange-Sperandio |
Scientific Reports | 2019 |
Diagnostic role of kidney injury molecule-1 in renal cell carcinoma
KJ Zhang, GD Wilson, S Kara, A Majeske, PL Zhang, JM Hafron |
International Urology and Nephrology | 2019 |
Kidney injury molecule-1, a sensitive and specific marker for identifying acute proximal tubular injury, can be used to predict renal functional recovery in native renal biopsies
W Yin, T Kumar, Z Lai, X Zeng, HD Kanaan, W Li, PL Zhang |
International Urology and Nephrology | 2019 |
Dynamic variation of kidney injury molecule-1 mRNA and protein expression in blood and urine of renal transplant recipients: a cohort study
SK Shahbaz, F Pourrezagholi, M Nafar, P Ahmadpoor, M Barabadi, F Foroughi, M Hosseinzadeh, MS Yekaninejad, A Amirzargar |
Clinical and Experimental Nephrology | 2019 |
Kidney Injury Biomarkers in an Academic Hospital Setting: Where Are We Now?
van Duijl TT, Ruhaak LR, de Fijter JW, Cobbaert CM |
The Clinical Biochemist Reviews | 2019 |
Human Kidney on a Chip Assessment of Polymyxin Antibiotic Nephrotoxicity
Elijah Weber, Kevin A Lidberg, lu wang, Theo K Bammler, James MacDonald, Mavis Jiarong Li, Michelle Redhair, William M. Atkins, Cecilia K Tran, Kelly M. Hines, Josi Herron, Libin Xu, Maria B. Monteiro, Susanne Ramm, Vishal Vaidya, Martti Vaara, Timo Vaara, Jonathan Himmelfarb, Edward J. Kelly |
JCI Insight | 2018 |
Clearance of Apoptotic Cells by Tissue Epithelia: A Putative Role for Hepatocytes in Liver Efferocytosis
SP Davies, GM Reynolds, Z Stamataki |
Frontiers in immunology | 2018 |
TIM-1 Mediates Dystroglycan-Independent Entry of Lassa Virus
RB Brouillette, EK Phillips, R Patel, W Mahauad-Fernandez, S Moller-Tank, KJ Rogers, JA Dillard, AL Cooney, L Martinez-Sobrido, C Okeoma, W Maury, RM Sandri-Goldin |
Journal of virology | 2018 |
Immune mechanisms in the different phases of acute tubular necrosis
F Kundert, L Platen, T Iwakura, Z Zhao, JA Marschner, HJ Anders |
Kidney Research and Clinical Practice | 2018 |
Meis1 is specifically upregulated in kidney myofibroblasts during aging and injury but is not required for kidney homeostasis or fibrotic response
M Chang-Panesso, FF Kadyrov, FG Machado, A Kumar, BD Humphreys |
American journal of physiology. Renal physiology | 2018 |
Uromodulin deficiency alters tubular injury and interstitial inflammation but not fibrosis in experimental obstructive nephropathy
O Maydan, PG McDade, Y Liu, XR Wu, DG Matsell, AA Eddy |
Physiological Reports | 2018 |
HIV internalization into oral and genital epithelial cells by endocytosis and macropinocytosis leads to viral sequestration in the vesicles
A Yasen, R Herrera, K Rosbe, K Lien, SM Tugizov |
Virology | 2018 |
Tctex-1, a novel interaction partner of Kidney Injury Molecule-1, is required for efferocytosis
OZ Ismail, S Sriranganathan, X Zhang, JV Bonventre, AS Zervos, L Gunaratnam |
Journal of Cellular Physiology | 2018 |
Urinary biomarkers predict advanced acute kidney injury after cardiovascular surgery
JJ Wang, NH Chi, TM Huang, R Connolly, LW Chen, SC Chueh, WC Kan, CC Lai, VC Wu, JT Fang, TS Chu, KD Wu |
Critical Care | 2018 |
Advances in predictive in vitro models of drug-induced nephrotoxicity
JY Soo, J Jansen, R Masereeuw, MH Little |
Nature Reviews Nephrology | 2018 |
Markers of early progressive renal decline in type 2 diabetes suggest different implications for etiological studies and prognostic tests development
N Nowak, J Skupien, AM Smiles, M Yamanouchi, MA Niewczas, AT Galecki, KL Duffin, MD Breyer, N Pullen, JV Bonventre, AS Krolewski |
Kidney International | 2018 |
Dan-Lou Prescription Inhibits Foam Cell Formation Induced by ox-LDL via the TLR4/NF-κB and PPARγ Signaling Pathways
LN Gao, X Zhou, YR Lu, K Li, S Gao, CQ Yu, YL Cui |
Frontiers in physiology | 2018 |
Kidney Injury Molecule-1 Identifies Antemortem Injury in Postmortem Adult and Fetal Kidney
W Yin, PL Zhang, J Macknis, F Lin, JV Bonventre |
American journal of physiology. Renal physiology | 2018 |
Independent modes of disease repair by AIM protein distinguished in AIM-felinized mice
R Sugisawa, G Komatsu, E Hiramoto, N Takeda, K Yamamura, S Arai, T Miyazaki |
Scientific Reports | 2018 |
Urinary Tubular Injury Biomarkers Are Associated With ESRD and Death in the REGARDS Study
RF Dubin, S Judd, R Scherzer, M Shlipak, DG Warnock, M Cushman, M Sarnak, C Parikh, M Bennett, N Powe, CA Peralta |
Kidney International Reports | 2018 |
Urinary Biomarkers of Aminoglycoside-Induced Nephrotoxicity in Cystic Fibrosis: Kidney Injury Molecule-1 and Neutrophil Gelatinase-Associated Lipocalin
SJ McWilliam, DJ Antoine, AL Jorgensen, RL Smyth, M Pirmohamed |
Scientific Reports | 2018 |
Twenty-four-hour normothermic perfusion of discarded human kidneys with urine recirculation
A Weissenbacher, LL Faro, O Boubriak, MF Soares, IS Roberts, JP Hunter, D Voyce, N Mikov, A Cook, RJ Ploeg, CC Coussios, PJ Friend |
American Journal of Transplantation | 2018 |
Identification of Urinary Activin A as a Novel Biomarker Reflecting the Severity of Acute Kidney Injury
S Takahashi, M Nakasatomi, Y Takei, H Ikeuchi, T Sakairi, Y Kaneko, K Hiromura, Y Nojima, A Maeshima |
Scientific Reports | 2018 |
Measurement of urinary biomarkers in a case of tubulointerstitial nephritis and uveitis syndrome during glucocorticoid treatment
M Sugiyama |
CEN Case Reports | 2018 |
Efferocytosis and autoimmune disease
M Kawano, S Nagata |
International Immunology | 2018 |
Associations of Circulating Protein Levels With Lipid Fractions in the General Population
SM Figarska, S Gustafsson, J Sundström, J Ärnlöv, A Mälarstig, S Elmståhl, T Fall, L Lind, E Ingelsson |
Arteriosclerosis, thrombosis, and vascular biology | 2018 |
Technology Transfer of the Microphysiological Systems: A Case Study of the Human Proximal Tubule Tissue Chip
C Sakolish, EJ Weber, EJ Kelly, J Himmelfarb, R Mouneimne, FA Grimm, JS House, T Wade, A Han, WA Chiu, I Rusyn |
Scientific Reports | 2018 |
A scavenging system against internal pathogens promoted by the circulating protein apoptosis inhibitor of macrophage (AIM)
S Arai, T Miyazaki |
Seminars in Immunopathology | 2018 |
Reconstructing the Human Renal Vascular-Tubular Unit In Vitro
SG Rayner, KT Phong, J Xue, D Lih, SJ Shankland, EJ Kelly, J Himmelfarb, Y Zheng |
Advanced Healthcare Materials | 2018 |
Circulating Biomarker Levels in Patients With Stage 5 Chronic Kidney Disease With Respect to Neurovascular Diseases
J Lee, R McMillan, L Skiadopoulos, V Bansal, J Biller, D Hoppensteadt, J Fareed |
Clinical and Applied Thrombosis/Hemostasis | 2018 |
Quantification of Efferocytosis by Single-cell Fluorescence Microscopy
K Taruc, C Yin, DG Wootton, B Heit |
Journal of visualized experiments : JoVE | 2018 |
A specific immunoassay for detection of feline kidney injury molecule 1
Bland SK, Clark ME, Côté O, Bienzle D |
Journal of Feline Medicine & Surgery | 2018 |
Apoptosis inhibitor of macrophage ameliorates fungus-induced peritoneal injury model in mice
T Tomita, S Arai, K Kitada, M Mizuno, Y Suzuki, F Sakata, D Nakano, E Hiramoto, Y Takei, S Maruyama, A Nishiyama, S Matsuo, T Miyazaki, Y Ito |
Scientific Reports | 2017 |
Engulfment signals and the phagocytic machinery for apoptotic cell clearance
SY Park, IS Kim |
Experimental & molecular medicine | 2017 |
Efferocytosis Signaling in the Regulation of Macrophage Inflammatory Responses
MR Elliott, KM Koster, PS Murphy |
Journal of immunology (Baltimore, Md. : 1950) | 2017 |
The Tubulointerstitial Pathophysiology of Progressive Kidney Disease
HW Schnaper |
Advances in Chronic Kidney Disease | 2017 |
Novel Biomarkers in the Diagnosis of Chronic Kidney Disease and the Prediction of Its Outcome
J Rysz, A Gluba-Brzózka, B Franczyk, Z Jabłonowski, A Ciałkowska-Rysz |
International journal of molecular sciences | 2017 |
CD74 Deficiency Mitigates Systemic Lupus Erythematosus-like Autoimmunity and Pathological Findings in Mice
Yi Zhou, Huimei Chen, Li Liu, Xueqing Yu, Galina K Sukhova, Min Yang, Lijun Zhang, Vasileios C Kyttaris, George C Tsokos, Isaac E Stillman, Takaharu Ichimura, Joseph V Bonventre, Peter Libby, Guo-Ping Shi |
Journal of immunology (Baltimore, Md. : 1950) | 2017 |
Extracellular Signal–Regulated Kinase 1/2 Regulates Mouse Kidney Injury Molecule-1 Expression Physiologically and Following Ischemic and Septic Renal Injury
JB Collier, RG Schnellmann |
The Journal of pharmacology and experimental therapeutics | 2017 |
Fibrotic Changes Mediating Acute Kidney Injury to Chronic Kidney Disease Transition
EÓ hAinmhire, BD Humphreys |
Nephron. Clinical practice | 2017 |
Urinary protein biomarkers of kidney injury in patients receiving cisplatin chemotherapy
B George, MS Joy, LM Aleksunes |
Experimental biology and medicine (Maywood, N.J.) | 2017 |
Isolation and characterization of urinary extracellular vesicles: implications for biomarker discovery
ML Merchant, IM Rood, JK Deegens, JB Klein |
Nature Reviews Nephrology | 2017 |
Detection of Drug-Induced Acute Kidney Injury in Humans Using Urinary KIM-1, miR-21, -200c, and -423
M Pavkovic, C Robinson-Cohen, AS Chua, O Nicoara, M Cárdenas-González, V Bijol, K Ramachandran, L Hampson, M Pirmohamed, DJ Antoine, G Frendl, J Himmelfarb, SS Waikar, VS Vaidya |
Toxicological Sciences | 2016 |
Extracellular Vesicles Exploit Viral Entry Routes for Cargo Delivery
HM van Dongen, N Masoumi, KW Witwer, DM Pegtel |
Microbiology and molecular biology reviews : MMBR | 2016 |
Biomarkers in acute kidney injury - pathophysiological basis and clinical performance
EV Schrezenmeier, J Barasch, K Budde, T Westhoff, KM Schmidt-Ott |
Acta physiologica (Oxford, England) | 2016 |
The potential use of biomarkers in predicting contrast-induced acute kidney injury
M Andreucci, T Faga, E Riccio, M Sabbatini, A Pisani, A Michael |
International journal of nephrology and renovascular disease | 2016 |
Macrophages redirect phagocytosis by non-professional phagocytes and influence inflammation
CZ Han, IJ Juncadella, JM Kinchen, MW Buckley, AL Klibanov, K Dryden, S Onengut-Gumuscu, U Erdbrügger, SD Turner, YM Shim, KS Tung, KS Ravichandran |
Nature | 2016 |
The proximal tubule is the primary target of injury and progression of kidney disease: role of the glomerulotubular junction
RL Chevalier |
American journal of physiology. Renal physiology | 2016 |
Renal-targeting triptolide-glucosamine conjugate exhibits lower toxicity and superior efficacy in attenuation of ischemia/reperfusion renal injury in rats
Y Fu, Q Lin, T Gong, X Sun, Z Zhang |
Acta Pharmacologica Sinica | 2016 |
Kidney injury molecule-1 (KIM-1) mediates renal epithelial cell repair via ERK MAPK signaling pathway
Z Zhang, CX Cai |
Molecular and Cellular Biochemistry | 2016 |
Acute kidney injury and chronic kidney disease: From the laboratory to the clinic
DA Ferenbach, JV Bonventre |
Néphrologie & Thérapeutique | 2016 |
Environmental exposure to arsenic and chromium in children is associated with kidney injury molecule-1
M Cárdenas-González, C Osorio-Yáñez, O Gaspar-Ramírez, M Pavković, A Ochoa-Martínez, D López-Ventura, M Medeiros, OC Barbier, IN Pérez-Maldonado, VS Sabbisetti, JV Bonventre, VS Vaidya |
Environmental Research | 2016 |
Apoptosis inhibitor of macrophage protein enhances intraluminal debris clearance and ameliorates acute kidney injury in mice
S Arai, K Kitada, T Yamazaki, R Takai, X Zhang, Y Tsugawa, R Sugisawa, A Matsumoto, M Mori, Y Yoshihara, K Doi, N Maehara, S Kusunoki, A Takahata, E Noiri, Y Suzuki, N Yahagi, A Nishiyama, L Gunaratnam, T Takano, T Miyazaki |
Nature Medicine | 2016 |
Development of a microphysiological model of human kidney proximal tubule function
EJ Weber, A Chapron, BD Chapron, JL Voellinger, KA Lidberg, CK Yeung, Z Wang, Y Yamaura, DW Hailey, T Neumann, DD Shen, KE Thummel, KA Muczynski, J Himmelfarb, EJ Kelly |
Kidney International | 2016 |
Urinary Biomarkers KIM-1 and NGAL for Detection of Chronic Kidney Disease of Uncertain Etiology (CKDu) among Agricultural Communities in Sri Lanka
PM de Silva, KS Abdul, EM Eakanayake, SS Jayasinghe, C Jayasumana, HB Asanthi, HS Perera, GG Chaminda, EP Chandana, SH Siribaddana, JM Vinetz |
PLoS neglected tropical diseases | 2016 |
Aminoglycoside-induced nephrotoxicity in children
SJ McWilliam, DJ Antoine, RL Smyth, M Pirmohamed |
Pediatric Nephrology | 2016 |
A proteolytic modification of AIM promotes its renal excretion
T Yamazaki, R Sugisawa, E Hiramoto, R Takai, A Matsumoto, Y Senda, K Nakashima, PS Nelson, JM Lucas, A Morgan, Z Li, K Yamamura, S Arai, T Miyazaki |
Scientific Reports | 2016 |
A kidney injury molecule-1 (Kim-1) gene reporter in a mouse artificial chromosome: the responsiveness to cisplatin toxicity in immortalized mouse kidney S3 cells: Kim-1 reporter for cisplatin toxicity
K Kokura, Y Kuromi, T Endo, N Anzai, Y Kazuki, M Oshimura, T Ohbayashi |
The Journal of Gene Medicine | 2016 |
Rab17 mediates differential antigen sorting following efferocytosis and phagocytosis
C Yin, Y Kim, D Argintaru, B Heit |
Cell Death and Disease | 2016 |
Impact of feline AIM on the susceptibility of cats to renal disease
R Sugisawa, E Hiramoto, S Matsuoka, S Iwai, R Takai, T Yamazaki, N Mori, Y Okada, N Takeda, K Yamamura, T Arai, S Arai, T Miyazaki |
Scientific Reports | 2016 |
KIM-1/TIM-1 mediated-phagocytosis reduces acute injury to the kidney
Li Yang, Craig Brooks, Sheng Xiao, Venkata Sabbisetti, Melissa Yeung, Li-Li Hsiao, Takaharu Ichimura, Vijay Kuchroo, Joseph V. Bonventre |
Journal of Clinical Investigation | 2015 |
Severity and Frequency of Proximal Tubule Injury Determines Renal Prognosis
K Takaori, J Nakamura, S Yamamoto, H Nakata, Y Sato, M Takase, M Nameta, T Yamamoto, AN Economides, K Kohno, H Haga, K Sharma, M Yanagita |
Journal of the American Society of Nephrology : JASN | 2015 |
TIM-1 Signaling Is Required for Maintenance and Induction of Regulatory B Cells: Breg Induction Requires TIM-1 Signaling
MY Yeung, Q Ding, CR Brooks, S Xiao, CJ Workman, DA Vignali, T Ueno, RF Padera, VK Kuchroo, N Najafian, DM Rothstein |
American Journal of Transplantation | 2015 |
Cardiorenal Syndrome Type 1: Activation of Dual Apoptotic Pathways
S Pastori, GM Virz, A Brocca, M Cal, V Cantaluppi, C Castellani, M Fedrigo, G Thiene, ML Valente, A Angelini, G Vescovo, C Ronco |
Cardiorenal Medicine | 2015 |
Subclinical kidney injury before and 1 year after bariatric surgery among adolescents with severe obesity: Subclinical Kidney Injury and Severe Obesity
N Xiao, P Devarajan, TH Inge, TM Jenkins, M Bennett, MM Mitsnefes |
Obesity | 2015 |
Urine Injury Biomarkers and Risk of Adverse Outcomes in Recipients of Prevalent Kidney Transplants: The Folic Acid for Vascular Outcome Reduction in Transplantation Trial
N Bansal, MA Carpenter, DE Weiner, AS Levey, M Pfeffer, JW Kusek, J Cai, LG Hunsicker, M Park, M Bennett, KD Liu, C Hsu |
Journal of the American Society of Nephrology : JASN | 2015 |
Apoptotic cell recognition receptors and scavenger receptors
KK Penberthy, KS Ravichandran |
Immunological Reviews | 2015 |
The Macrophage Phagocytic Receptor CD36 Promotes Fibrogenic Pathways on Removal of Apoptotic Cells during Chronic Kidney Injury
S Pennathur, K Pasichnyk, NM Bahrami, L Zeng, M Febbraio, I Yamaguchi, DM Okamura |
The American Journal of Pathology | 2015 |
Mechanisms of maladaptive repair after AKI leading to accelerated kidney ageing and CKD
DA Ferenbach, JV Bonventre |
Nature Reviews Nephrology | 2015 |
MG53-mediated cell membrane repair protects against acute kidney injury
P Duann, H Li, P Lin, T Tan, Z Wang, K Chen, X Zhou, K Gumpper, H Zhu, T Ludwig, PJ Mohler, B Rovin, WT Abraham, C Zeng, J Ma |
Science Translational Medicine | 2015 |
Kidney injury molecule-1 expression in human kidney transplants with interstitial fibrosis and tubular atrophy
AL Nogare, FV Veronese, VN Carpio, RM Montenegro, JA Pedroso, KL Pegas, LF Gonçalves, RC Manfro |
BMC Nephrology | 2015 |
No increase in Kidney Injury Molecule-1 and Neutrophil Gelatinase-Associated Lipocalin excretion following intravenous contrast enhanced-CT
J Kooiman, WR van de Peppel, YW Sijpkens, HF Brulez, PM de Vries, MA Nicolaie, H Putter, MV Huisman, W der Kooij, C Kooten, TJ Rabelink |
European Radiology | 2015 |
Chronic Kidney Disease Influences Multiple Systems: Describing the Relationship between Oxidative Stress, Inflammation, Kidney Damage, and Concomitant Disease
PS Tucker, AT Scanlan, VJ Dalbo |
Oxidative medicine and cellular longevity | 2015 |
Tim-1 Is Essential for Induction and Maintenance of IL-10 in Regulatory B Cells and Their Regulation of Tissue Inflammation
S Xiao, CR Brooks, RA Sobel, VK Kuchroo |
Journal of immunology (Baltimore, Md. : 1950) | 2015 |
Proximal Tubular Injury in Medullary Rays Is an Early Sign of Acute Tacrolimus Nephrotoxicity
D Cosner, X Zeng, PL Zhang |
Journal of Transplantation | 2015 |
Safety and Efficacy Endpoints for Mesenchymal Stromal Cell Therapy in Renal Transplant Recipients
JR Bank, TJ Rabelink, JW de Fijter, ME Reinders |
Journal of Immunology Research | 2015 |
Interaction between TIM-1 and NPC1 Is Important for Cellular Entry of Ebola Virus
M Kuroda, D Fujikura, A Nanbo, A Marzi, O Noyori, M Kajihara, J Maruyama, K Matsuno, H Miyamoto, R Yoshida, H Feldmann, A Takada, A García-Sastre |
Journal of virology | 2015 |
Effects of carnitine on oxidative stress response to intravenous iron administration to patients with CKD: impact of haptoglobin phenotype
Z Armaly, AA el Qader, A Jabbour, K Hassan, R Ramadan, A Bowirrat, B Bisharat |
BMC Nephrology | 2015 |
Kidney Injury Molecule-1 Enhances Endocytosis of Albumin in Renal Proximal Tubular Cells: KIM-1 EXPRESSION AND TUBULAR ALBUMIN HANDLING
X Zhao, C Jiang, R Olufade, D Liu, N Emmett |
Journal of Cellular Physiology | 2015 |
Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids
Benjamin S Freedman, Craig R Brooks, Albert Q Lam, Hongxia Fu, Ryuji Morizane, Vishesh Agrawal, Abdelaziz F Saad, Michelle K Li, Michael R Hughes, Ryan Vander Werff, Derek T Peters, Junjie Lu, Anna Baccei, Andrew M Siedlecki, M Todd Valerius, Kiran Musunuru, Kelly M McNagny, Theodore I Steinman, Jing Zhou, Paul H Lerou, Joseph V Bonventre |
Nature Communications | 2015 |
KIM-1-/TIM-1-mediated phagocytosis links ATG5-/ULK1-dependent clearance of apoptotic cells to antigen presentation
CR Brooks, MY Yeung, YS Brooks, H Chen, T Ichimura, JM Henderson, JV Bonventre |
The EMBO Journal | 2015 |
G protein α 12 (Gα 12 ) is a negative regulator of kidney injury molecule-1-mediated efferocytosis
OZ Ismail, X Zhang, JV Bonventre, L Gunaratnam |
American journal of physiology. Renal physiology | 2015 |
Mammalian Target of Rapamycin Mediates Kidney Injury Molecule 1-Dependent Tubule Injury in a Surrogate Model
W Yin, SM Naini, G Chen, DM Hentschel, BD Humphreys, JV Bonventre |
Journal of the American Society of Nephrology : JASN | 2015 |
Evaluation of cystatin C as an early biomarker of cadmium nephrotoxicity in the rat
WC Prozialeck, A VanDreel, CD Ackerman, I Stock, A Papaeliou, C Yasmine, K Wilson, PC Lamar, VL Sears, JZ Gasiorowski, KM DiNovo, VS Vaidya, JR Edwards |
BioMetals | 2015 |
Kidney Injury Molecule-1 and Cardiovascular Diseases: From Basic Science to Clinical Practice
B Medić, B Rovčanin, GB Jovanović, S Radojević-Škodrić, M Prostran |
BioMed Research International | 2015 |
Modeling Kidney Disease with iPS Cells
Freedman |
Biomarker insights | 2015 |
No Effect of Remote Ischemic Conditioning Strategies on Recovery from Renal Ischemia-Reperfusion Injury and Protective Molecular Mediators
C Kierulf-Lassen, ML Kristensen, H Birn, B Jespersen, R Nørregaard, F Gallyas |
PloS one | 2015 |
Efferocytosis creates a tumor microenvironment supportive of tumor survival and metastasis.
Vaught DB, Stanford JC, Cook RS |
Cancer Cell & Microenvironment | 2015 |
KIM-1/TIM-1 in proximal tubular cell immune response
Brooks CR, Bonventre JV |
Oncotarget | 2015 |
Kidney fibrosis: recent advances
Jeremy Duffield |
Journal of Clinical Investigation | 2014 |
A basic science view of acute kidney injury biomarkers
JR Charlton, D Portilla, MD Okusa |
Nephrology Dialysis Transplantation | 2014 |
Biomarkers of AKI: A Review of Mechanistic Relevance and Potential Therapeutic Implications
JL Alge, JM Arthur |
Clinical journal of the American Society of Nephrology : CJASN | 2014 |
Effects of cell-type-specific expression of a pan-caspase inhibitor on renal fibrogenesis
T Inoue, T Kusano, K Tomori, H Nakamoto, H Suzuki, H Okada |
Clinical and Experimental Nephrology | 2014 |
Cilostazol Renoprotective Effect: Modulation of PPAR-γ, NGAL, KIM-1 and IL-18 Underlies Its Novel Effect in a Model of Ischemia-Reperfusion
D Ragab, DM Abdallah, HS El-Abhar, G Drossopoulou |
PloS one | 2014 |
Albumin and glycated albumin activate KIM-1 release in tubular epithelial cells through distinct kinetics and mechanisms
AI Lim, LY Chan, SC Tang, KN Lai, JC Leung |
Inflammation Research | 2014 |
How the Innate Immune System Senses Trouble and Causes Trouble
T Hato, PC Dagher |
Clinical journal of the American Society of Nephrology : CJASN | 2014 |
Predictive value of urinary and serum biomarkers in young children with febrile urinary tract infections
HE Yim, H Yim, ES Bae, SU Woo, KH Yoo |
Pediatric Nephrology | 2014 |
Emerging Biomarkers and Metabolomics for Assessing Toxic Nephropathy and Acute Kidney Injury (AKI) in Neonatology
M Mussap, A Noto, V Fanos, JN van Anker |
BioMed Research International | 2014 |
Defining the Acute Kidney Injury and Repair Transcriptome
S Kumar, J Liu, AP McMahon |
Seminars in Nephrology | 2014 |
Acute pretreatment with chloroquine attenuates renal I/R injury in rats
Z Todorovic, B Medic, G Basta-Jovanovic, SR Skodric, R Stojanovic, B Rovcanin, M Prostran |
PloS one | 2014 |
Kidney injury molecule-1 is involved in the chemotactic migration of mesenchymal stem cells
KM Park, HS Nam, PK Teotia, KH Hussein, SH Hong, JI Yun, HM Woo |
In vitro cellular & developmental biology. Animal | 2014 |
Urinary kidney injury molecule-1 is related to pathologic involvement in IgA nephropathy with normotension, normal renal function and mild proteinuria
P Xu, L Wei, W Shang, S Tian, D Gu, T Yan, S Lin |
BMC Nephrology | 2014 |
The Hemodynamic and Nonhemodynamic Crosstalk in Cardiorenal Syndrome Type 1
GM Virzì, A Clementi, A Brocca, M Cal, G Vescovo, A Granata, C Ronco |
Cardiorenal Medicine | 2014 |
Phosphatidylserine receptors: Enhancers of enveloped virus entry and infection
S Moller-Tank, W Maury |
Virology | 2014 |
Characterization of Kidney Injury Molecule-1 in Cats
SK Bland, O Côté, ME Clark, J DeLay, D Bienzle |
Journal of Veterinary Internal Medicine | 2014 |
Use of urinary renal biomarkers to evaluate the nephrotoxic effects of melamine or cyanuric acid in non-pregnant and pregnant rats
OJ Bandele, CB Stine, M Ferguson, T Black, N Olejnik, Z Keltner, ER Evans, TC Crosby, R Reimschuessel, RL Sprando |
Food and Chemical Toxicology | 2014 |
Erythrophagocytosis of Lead-Exposed Erythrocytes by Renal Tubular Cells: Possible Role in Lead-Induced Nephrotoxicity
SY Kwon, ON Bae, JY Noh, K Kim, S Kang, YJ Shin, KM Lim, JH Chung |
Environmental Health Perspectives | 2014 |
Accelerated receptor shedding inhibits kidney injury molecule-1 (KIM-1)-mediated efferocytosis
R Gandhi, J Yi, J Ha, H Shi, O Ismail, S Nathoo, JV Bonventre, X Zhang, L Gunaratnam |
American journal of physiology. Renal physiology | 2014 |
Galectin-9 Signaling through TIM-3 Is Involved in Neutrophil-Mediated Gram-Negative Bacterial Killing: An Effect Abrogated within the Cystic Fibrosis Lung
I Vega-Carrascal, DA Bergin, OJ McElvaney, C McCarthy, N Banville, K Pohl, M Hirashima, VK Kuchroo, EP Reeves, NG McElvaney |
Journal of immunology (Baltimore, Md. : 1950) | 2014 |
Chronic Epithelial Kidney Injury Molecule-1 Expression in Mice Causes Inflammation, Fibrosis and Kidney Failure
Benjamin D. Humphreys, Fengfeng Xu, Venkata Sabbisetti, Ivica Grgic, Said Naini, NingNing Wang, Guochun Chen, Sheng Xiao, Dhruti Patel, Joel Henderson, Takaharu Ichimura, Shan Mou, Savuth Soeung, Andrew McMahon, Vijay Kuchroo, Joseph V. Bonventre |
Journal of Clinical Investigation | 2013 |
l-Citrulline Protects from Kidney Damage in Type 1 Diabetic Mice
MJ Romero, L Yao, S Sridhar, A Bhatta, H Dou, G Ramesh, MW Brands, DM Pollock, RB Caldwell, SD Cederbaum, CA Head, Z Bagi, R Lucas, RW Caldwell |
Frontiers in immunology | 2013 |
New Biomarkers for the Quick Detection of Acute Kidney Injury
A Simsek, V Tugcu, AI Tasci |
ISRN Nephrology | 2013 |
Clinical Application Neutrophil Gelatinase-Associated Lipocalin and Kidney Injury Molecule-1 as Indicators of Inflammation Persistence and Acute Kidney Injury in Children with Urinary Tract Infection
S Petrovic, N Bogavac-Stanojevic, A Peco-Antic, I Ivanisevic, J Kotur-Stevuljevic, D Paripovic, M Sopic, Z Jelic-Ivanovic |
BioMed Research International | 2013 |
Role of New Biomarkers: Functional and Structural Damage
E Tsigou, V Psallida, C Demponeras, E Boutzouka, G Baltopoulos |
Critical care research and practice | 2013 |
TLR-2/TLR-4 TREM-1 Signaling Pathway Is Dispensable in Inflammatory Myeloid Cells during Sterile Kidney Injury
G Campanholle, K Mittelsteadt, S Nakagawa, A Kobayashi, SL Lin, SA Gharib, JW Heinecke, JA Hamerman, WA Altemeier, JS Duffield |
PloS one | 2013 |
Sisters in arms: myeloid and tubular epithelial cells shape renal innate immunity
T Hato, TM El-Achkar, PC Dagher |
American journal of physiology. Renal physiology | 2013 |
A Bioinformatics Approach Identifies Signal Transducer and Activator of Transcription-3 and Checkpoint Kinase 1 as Upstream Regulators of Kidney Injury Molecule-1 after Kidney Injury
AK Ajay, TM Kim, V Ramirez-Gonzalez, PJ Park, DA Frank, VS Vaidya |
Journal of the American Society of Nephrology : JASN | 2013 |
Bilirubin attenuates the renal tubular injury by inhibition of oxidative stress and apoptosis
SW Oh, ES Lee, S Kim, KY Na, DW Chae, S Kim, HJ Chin |
BMC Nephrology | 2013 |
Scavenger receptors in homeostasis and immunity
J Canton, D Neculai, S Grinstein |
Nature Reviews Immunology | 2013 |
Cellular Factors Implicated in Filovirus Entry
S Bhattacharyya, TJ Hope |
Advances in Virology | 2013 |
The current status of biomarkers for predicting toxicity
S Campion, J Aubrecht, K Boekelheide, DW Brewster, VS Vaidya, L Anderson, D Burt, E Dere, K Hwang, S Pacheco, J Saikumar, S Schomaker, M Sigman, F Goodsaid |
Expert Opinion on Drug Metabolism & Toxicology | 2013 |
Urine kidney injury molecule-1: a potential non-invasive biomarker for patients with renal cell carcinoma
PL Zhang, JW Mashni, VS Sabbisetti, CM Schworer, GD Wilson, SC Wolforth, KM Kernen, BD Seifman, MB Amin, TJ Geddes, F Lin, JV Bonventre, JM Hafron |
International Urology and Nephrology | 2013 |
Urine free light chains as a novel biomarker of acute kidney allograft injury
R Zhang, M Li, KK Chouhan, EE Simon, LL Hamm, V Batuman |
Clinical Transplantation | 2013 |
Tissue kidney injury molecule-1 expression in the prediction of renal function for several years after kidney biopsy
SS Ogrizovic, S Bojic, G Basta-Jovanovic, S Radojevic, J Pavlovic, JK Stevuljevic, V Dopsaj, R Naumovic |
Disease Markers | 2013 |
Role of the phosphatidylserine receptor TIM-1 in enveloped-virus entry
S Moller-Tank, AS Kondratowicz, RA Davey, PD Rennert, W Maury |
Journal of virology | 2013 |
EphrinB2 reverse signaling protects against capillary rarefaction and fibrosis after kidney injury
Y Kida, N Ieronimakis, C Schrimpf, M Reyes, JS Duffield |
Journal of the American Society of Nephrology : JASN | 2013 |
Performance of Kidney Injury Molecule-1 and Liver Fatty Acid-Binding Protein and Combined Biomarkers of AKI after Cardiac Surgery
CR Parikh, H Thiessen-Philbrook, AX Garg, D Kadiyala, MG Shlipak, JL Koyner, CL Edelstein, P Devarajan, UD Patel, M Zappitelli, CD Krawczeski, CS Passik, SG Coca |
Clinical journal of the American Society of Nephrology : CJASN | 2013 |
Chemokine Receptor Ccr1 Drives Neutrophil-Mediated Kidney Immunopathology and Mortality in Invasive Candidiasis
MS Lionakis, BG Fischer, JK Lim, M Swamydas, W Wan, CC Lee, JI Cohen, P Scheinberg, JL Gao, PM Murphy |
PLoS pathogens | 2012 |
Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice
S Xiao, CR Brooks, C Zhu, C Wu, JM Sweere, S Petecka, A Yeste, FJ Quintana, T Ichimura, RA Sobel, JV Bonventre, VK Kuchroo |
Proceedings of the National Academy of Sciences | 2012 |
Marking Renal Injury: Can We Move Beyond Serum Creatinine?
JL Slocum, M Heung, S Pennathur |
Translational research : the journal of laboratory and clinical medicine | 2012 |
Secreted Factors from Bone Marrow Stromal Cells Upregulate IL-10 and Reverse Acute Kidney Injury
JM Milwid, T Ichimura, M Li, Y Jiao, J Lee, JS Yarmush, B Parekkadan, AW Tilles, JV Bonventre, ML Yarmush |
Stem Cells International | 2012 |
Biomarkers for the prediction of acute kidney injury: a narrative review on current status and future challenges
HR de Geus, MG Betjes, J Bakker |
Clinical Kidney Journal | 2012 |
Interactions of human T cell immunoglobin mucins with apoptotic cells
Z Chen, J Qing, L Hu |
Journal of Huazhong University of Science and Technology [Medical Sciences] | 2012 |
The role of TIM-containing molecules in airway disease and their potential as therapeutic targets
I Vega-Carrascal, EP Reeves, NG McElvaney |
Journal of inflammation research | 2012 |
Rapamycin Ameliorates Kidney Fibrosis by Inhibiting the Activation of mTOR Signaling in Interstitial Macrophages and Myofibroblasts
G Chen, H Chen, C Wang, Y Peng, L Sun, H Liu, F Liu |
PloS one | 2012 |
TIM Family Proteins Promote the Lysosomal Degradation of the Nuclear Receptor NUR77
S Balasubramanian, SK Kota, VK Kuchroo, BD Humphreys, TB Strom |
Science signaling | 2012 |
Kidney Injury Molecule-1 Is Up-Regulated in Renal Epithelial Cells in Response to Oxalate In Vitro and in Renal Tissues in Response to Hyperoxaluria In Vivo
L Khandrika, S Koul, RB Meacham, HK Koul |
PloS one | 2012 |
Kim-1/Tim-1 and immune cells: shifting sands
T Ichimura, CR Brooks, JV Bonventre |
Kidney international. Supplement | 2012 |
MicroRNA 21 promotes fibrosis of the kidney by silencing metabolic pathways
BN Chau, C Xin, J Hartner, S Ren, AP Castano, G Linn, J Li, PT Tran, V Kaimal, X Huang, AN Chang, S Li, A Kalra, M Grafals, D Portilla, DA MacKenna, SH Orkin, JS Duffield |
Science Translational Medicine | 2012 |
Mechanisms of cadmium-induced proximal tubule injury: new insights with implications for biomonitoring and therapeutic interventions
WC Prozialeck, JR Edwards |
The Journal of pharmacology and experimental therapeutics | 2012 |
Draper acts through the JNK pathway to control synchronous engulfment of dying germline cells by follicular epithelial cells
JI Etchegaray, AK Timmons, AP Klein, TL Pritchett, E Welch, TL Meehan, C Li, K McCall |
Development (Cambridge, England) | 2012 |
Host cell factors in filovirus entry: novel players, new insights.
Hofmann-Winkler H, Kaup F, Pöhlmann S |
Viruses | 2012 |
The TIM1 gene regulates susceptibility to severe Hepatitis A virus infection in humans
Hye-Young kim, María Belén Eyheramonho, Muriel Pichavant, Carlos Gonzalez Cambaceres, Ponpan Matangkasomubut, Guillermo Cervio, Silvina Kuperman, Rita Moreiro, Krishnamurthy Konduru, Mohanraj Manangeeswaran, Gordon Freeman, Gerardo Kaplan, Rosemarie DeKruyff, Dale Umetsu, Sergio Rosenzweig |
Journal of Clinical Investigation | 2011 |
Cellular pathways involved in renal ischemia
Joseph V. Bonventre, Li Yang |
Journal of Clinical Investigation | 2011 |
Diannexin Protects against Renal Ischemia Reperfusion Injury and Targets Phosphatidylserines in Ischemic Tissue
KE Wever, FA Wagener, C Frielink, OC Boerman, GJ Scheffer, A Allison, R Masereeuw, GA Rongen |
PloS one | 2011 |
Dangers Within: DAMP Responses to Damage and Cell Death in Kidney Disease
DL Rosin, MD Okusa |
Journal of the American Society of Nephrology : JASN | 2011 |
The TIM-1:TIM-4 Pathway Enhances Renal Ischemia-Reperfusion Injury
S Rong, JK Park, T Kirsch, H Yagita, H Akiba, O Boenisch, H Haller, N Najafian, A Habicht |
Journal of the American Society of Nephrology : JASN | 2011 |
Cytoglobin, a Novel Member of the Globin Family, Protects Kidney Fibroblasts against Oxidative Stress under Ischemic Conditions
H Nishi, R Inagi, N Kawada, K Yoshizato, I Mimura, T Fujita, M Nangaku |
The American Journal of Pathology | 2011 |
Metchnikoff’s Policemen—Macrophages in Development, Homeostasis and Regeneration
JA Stefater, S Ren, RA Lang, JS Duffield |
Trends in Molecular Medicine | 2011 |
Repair of injured proximal tubule does not involve specialized progenitors
BD Humphreys, S Czerniak, DP DiRocco, W Hasnain, R Cheema, JV Bonventre |
Proceedings of the National Academy of Sciences | 2011 |
Pathophysiology of ischemic acute kidney injury
AA Sharfuddin, BA Molitoris |
Nature Reviews Nephrology | 2011 |
THE EMERGING ROLE OF THE TIM MOLECULES IN TRANSPLANTATION
MY Yeung, M McGrath, N Najafian |
American Journal of Transplantation | 2011 |
Angiotensin II Activation of mTOR Results in Tubulointerstitial Fibrosis through Loss of N-Cadherin
A Whaley-Connell, J Habibi, Z Panfili, MR Hayden, S Bagree, R Nistala, S Hyder, B Krueger, V Demarco, L Pulakat, CM Ferrario, A Parrish, JR Sowers |
American Journal of Nephrology | 2011 |
T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus
AS Kondratowicz, NJ Lennemann, PL Sinn, RA Davey, CL Hunt, S Moller-Tank, DK Meyerholz, P Rennert, RF Mullins, M Brindley, LM Sandersfeld, K Quinn, M Weller, PB McCray, J Chiorini, W Maury |
Proceedings of the National Academy of Sciences | 2011 |
Glomerular Expression of Kidney Injury Molecule-1 and Podocytopenia in Diabetic Glomerulopathy
X Zhao, Y Zhang, L Li, D Mann, JD Imig, N Emmett, G Gibbons, LM Jin |
American Journal of Nephrology | 2011 |
Biomarkers of Immunosuppressant Organ Toxicity after Transplantation - Status, Concepts and Misconceptions
U Christians, J Klawitter, J Klawitter, N Brunner, V Schmitz |
Expert Opinion on Drug Metabolism & Toxicology | 2011 |
Beginnings of a good apoptotic meal: the find-me and eat-me signaling pathways
KS Ravichandran |
Immunity | 2011 |
Biomarkers for drug-induced renal damage and nephrotoxicity-an overview for applied toxicology
TC Fuchs, P Hewitt |
The AAPS Journal | 2011 |
Fyn binds to and phosphorylates T cell immunoglobulin and mucin domain-1 (Tim-1)
ML Curtiss, BS Hostager, E Stepniak, M Singh, N Manhica, J Knisz, G Traver, PD Rennert, JD Colgan, PB Rothman |
Molecular Immunology | 2011 |
Molecular Imaging of the Kidneys
Z Szabo, N Alachkar, J Xia, WB Mathews, H Rabb |
Seminars in Nuclear Medicine | 2011 |
Antagonism of TIM-1 blocks the development of disease in a humanized mouse model of allergic asthma
Sanchaita Sonar, Yen-Ming Hsu, Melanie Conrad, Gerard Majeau, Ayse Kilic, Ellen Garber, Yan Gao, Chioma Nwankwo, Gundi Willer, Jan Dudda, Hellen Kim, Veronique Bailly, Axel Pagenstecher, Paul Rennert, Harald Renz |
Journal of Clinical Investigation | 2010 |
TIM1 is an endogenous ligand for LMIR5/CD300b: LMIR5 deficiency ameliorates mouse kidney ischemia/reperfusion injury
Y Yamanishi, J Kitaura, K Izawa, A Kaitani, Y Komeno, M Nakamura, S Yamazaki, Y Enomoto, T Oki, H Akiba, T Abe, T Komori, Y Morikawa, H Kiyonari, T Takai, K Okumura, T Kitamura |
Journal of Experimental Medicine | 2010 |
T cell/transmembrane, Ig, and mucin-3 allelic variants differentially recognize phosphatidylserine and mediate phagocytosis of apoptotic cells
RH DeKruyff, X Bu, A Ballesteros, C Santiago, YL Chim, HH Lee, P Karisola, M Pichavant, GG Kaplan, DT Umetsu, GJ Freeman, JM Casasnovas |
Journal of immunology (Baltimore, Md. : 1950) | 2010 |
TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity: TIM genes: a family of PtdSer receptors
GJ Freeman, JM Casasnovas, DT Umetsu, RH DeKruyff |
Immunological Reviews | 2010 |
TIM2 Gene Deletion Results in Susceptibility to Cisplatin-Induced Kidney Toxicity
A Krishnamoorthy, ME Clement, E O'Leary, JV Bonventre, VS Vaidya |
Toxicological Sciences | 2010 |
Macrophage Wnt7b is critical for kidney repair and regeneration
SL Lin, B Li, S Rao, EJ Yeo, TE Hudson, BT Nowlin, H Pei, L Chen, JJ Zheng, TJ Carroll, JW Pollard, AP McMahon, RA Lang, JS Duffield |
Proceedings of the National Academy of Sciences | 2010 |
The melanoma-associated transmembrane glycoprotein Gpnmb controls trafficking of cellular debris for degradation and is essential for tissue repair
B Li, AP Castano, TE Hudson, BT Nowlin, SL Lin, JV Bonventre, KD Swanson, JS Duffield |
The FASEB Journal | 2010 |
Searching for novel intercellular signal-transducing molecules in the kidney and their clinical application
K Mori, M Mukoyama, K Nakao |
Clinical and Experimental Nephrology | 2010 |
Acute kidney injury in childhood: should we be worried about progression to CKD?
SL Goldstein, P Devarajan |
Pediatric Nephrology | 2010 |
The Use of Targeted Biomarkers for Chronic Kidney Disease
P Devarajan |
Advances in Chronic Kidney Disease | 2010 |
TIM-4, a Receptor for Phosphatidylserine, Controls Adaptive Immunity by Regulating the Removal of Antigen-Specific T Cells
LA Albacker, P Karisola, YJ Chang, SE Umetsu, M Zhou, O Akbari, N Kobayashi, N Baumgarth, GJ Freeman, DT Umetsu, RH DeKruyff |
Journal of immunology (Baltimore, Md. : 1950) | 2010 |
Emergence of biomarkers in nephropharmacology
E Khan, V Batuman, JJ Lertora |
Biomarkers in Medicine | 2010 |
Find-me and eat-me signals in apoptotic cell clearance: progress and conundrums
KS Ravichandran |
Journal of Experimental Medicine | 2010 |
Phosphatidylserine receptor Tim-4 is essential for the maintenance of the homeostatic state of resident peritoneal macrophages
K Wong, PA Valdez, C Tan, S Yeh, JA Hongo, W Ouyang |
Proceedings of the National Academy of Sciences | 2010 |
Tim-1 is induced on germinal centre B cells through B-cell receptor signalling but is not essential for the germinal centre response
SH Wong, JL Barlow, S Nabarro, PG Fallon, AN McKenzie |
Immunology | 2010 |
Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury
L Yang, TY Besschetnova, CR Brooks, JV Shah, JV Bonventre |
Nature Medicine | 2010 |
Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis
BD Humphreys, SL Lin, A Kobayashi, TE Hudson, BT Nowlin, JV Bonventre, MT Valerius, AP McMahon, JS Duffield |
The American Journal of Pathology | 2009 |
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd |
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology | 2009 |
Mediators of Inflammation in Acute Kidney Injury
A Akcay, Q Nguyen, CL Edelstein |
Mediators of Inflammation | 2009 |
Dysfunctional cystic fibrosis transmembrane conductance regulator inhibits phagocytosis of apoptotic cells with proinflammatory consequences
RW Vandivier, TR Richens, SA Horstmann, AM deCathelineau, M Ghosh, SD Reynolds, YQ Xiao, DW Riches, J Plumb, E Vachon, GP Downey, PM Henson |
American journal of physiology. Lung cellular and molecular physiology | 2009 |
Serum Amyloid P Inhibits Fibrosis Through Fc R-Dependent Monocyte-Macrophage Regulation in Vivo
AP Castaño, SL Lin, T Surowy, BT Nowlin, SA Turlapati, T Patel, A Singh, S Li, ML Lupher, JS Duffield |
Science Translational Medicine | 2009 |
The costimulatory role of TIM molecules
R Rodriguez-Manzanet, R DeKruyff, VK Kuchroo, DT Umetsu |
Immunological Reviews | 2009 |
Sequence, structure, function, immunity: structural genomics of costimulation
K Chattopadhyay, E Lazar-Molnar, Q Yan, R Rubinstein, C Zhan, V Vigdorovich, UA Ramagopal, J Bonanno, SG Nathenson, SC Almo |
Immunological Reviews | 2009 |
Comparative Analysis of Novel Noninvasive Renal Biomarkers and Metabonomic Changes in a Rat Model of Gentamicin Nephrotoxicity
M Sieber, D Hoffmann, M Adler, VS Vaidya, M Clement, JV Bonventre, N Zidek, E Rached, A Amberg, JJ Callanan, W Dekant, A Mally |
Toxicological Sciences | 2009 |
Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR
K Al-Nedawi, B Meehan, RS Kerbel, AC Allison, J Rak |
Proceedings of the National Academy of Sciences | 2009 |
Structural changes in the epithelium of the small intestine and immune cell infiltration of enteric ganglia following acute mucosal damage and local inflammation
L Pontell, P Castelucci, M Bagyánszki, T Jovic, M Thacker, K Nurgali, R Bron, JB Furness |
Virchows Archiv | 2009 |
Preclinical evaluation of novel urinary biomarkers of cadmium nephrotoxicity
WC Prozialeck, JR Edwards, VS Vaidya, JV Bonventre |
Toxicology and Applied Pharmacology | 2009 |
Expression of kidney injury molecule-1 (Kim-1) in relation to necrosis and apoptosis during the early stages of Cd-induced proximal tubule injury
WC Prozialeck, JR Edwards, PC Lamar, J Liu, VS Vaidya, JV Bonventre |
Toxicology and Applied Pharmacology | 2009 |
Reduction of proteinuria in adriamycin-induced nephropathy is associated with reduction of renal kidney injury molecule (Kim-1) over time
AB Kramer, MM van Timmeren, TA Schuurs, VS Vaidya, JV Bonventre, H Goor, G Navis |
American journal of physiology. Renal physiology | 2009 |
The ins and outs of phospholipid asymmetry in the plasma membrane: roles in health and disease
B Fadeel, D Xue |
Critical Reviews in Biochemistry and Molecular Biology | 2009 |
Tubular Expression of KIM-1 Does not Predict Delayed Function After Transplantation
B Schroppel, B Kruger, L Walsh, M Yeung, S Harris, K Garrison, J Himmelfarb, SM Lerner, JS Bromberg, PL Zhang, JV Bonventre, Z Wang, AB Farris, RB Colvin, BT Murphy, JP Vella |
Journal of the American Society of Nephrology : JASN | 2009 |
Pericytes and Perivascular Fibroblasts Are the Primary Source of Collagen-Producing Cells in Obstructive Fibrosis of the Kidney
SL Lin, T Kisseleva, DA Brenner, JS Duffield |
The American Journal of Pathology | 2008 |
TIM-1 and TIM-3 proteins in immune regulation
EW Su, JY Lin, LP Kane |
Cytokine | 2008 |
Emerging concepts in acute kidney injury following cardiac surgery
C Hudson, J Hudson, M Swaminathan, A Shaw, M Stafford-Smith, UD Patel |
Seminars in cardiothoracic and vascular anesthesia | 2008 |