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Citations to this article

Kidney injury molecule–1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells
Takaharu Ichimura, … , Jeremy S. Duffield, Joseph V. Bonventre
Takaharu Ichimura, … , Jeremy S. Duffield, Joseph V. Bonventre
Published April 15, 2008
Citation Information: J Clin Invest. 2008;118(5):1657-1668. https://doi.org/10.1172/JCI34487.
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Research Article Nephrology Article has an altmetric score of 5

Kidney injury molecule–1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells

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Abstract

Following injury, the clearance of apoptotic and necrotic cells is necessary for mitigation and resolution of inflammation and tissue repair. In addition to macrophages, which are traditionally assigned to this task, neighboring epithelial cells in the affected tissue are postulated to contribute to this process. Kidney injury molecule–1 (KIM-1 or TIM-1) is an immunoglobulin superfamily cell-surface protein not expressed by cells of the myeloid lineage but highly upregulated on the surface of injured kidney epithelial cells. Here we demonstrate that injured kidney epithelial cells assumed attributes of endogenous phagocytes. Confocal images confirm internalization of apoptotic bodies within KIM-1–expressing epithelial cells after injury in rat kidney tubules in vivo. KIM-1 was directly responsible for phagocytosis in cultured primary rat tubule epithelial cells and also porcine and canine epithelial cell lines. KIM-1 was able to specifically recognize apoptotic cell surface-specific epitopes phosphatidylserine, and oxidized lipoproteins, expressed by apoptotic tubular epithelial cells. Thus, KIM-1 is the first nonmyeloid phosphatidylserine receptor identified to our knowledge that transforms epithelial cells into semiprofessional phagocytes.

Authors

Takaharu Ichimura, Edwin J.P.v. Asseldonk, Benjamin D. Humphreys, Lakshman Gunaratnam, Jeremy S. Duffield, Joseph V. Bonventre

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M Xu, S Li, J Wang, S Huang, A Zhang, Y Zhang, W Gu, X Yu, Z Jia
Frontiers in Medicine 2021
Extracellular vesicles mediate cellular interactions in renal diseases—Novel views of intercellular communications in the kidney
PL Zhang, ML Liu
Journal of Cellular Physiology 2021
The Assessment of the Usefulness of Selected Markers in the Diagnosis of Chronic Kidney Disease in Children
A Będzichowska, K Jobs, M Kloc, A Bujnowska, B Kalicki
Biomarker insights 2021
Tim-1 Deficiency Aggravates High-Fat Diet-Induced Steatohepatitis in Mice
J George, Y Zhang, J Sloan, JM Sims, JD Imig, X Zhao
Frontiers in immunology 2021
Novel Roles of the Tim Family in Immune Regulation and Autoimmune Diseases
Y Liu, H Chen, Z Chen, J Qiu, H Pang, Z Zhou
Frontiers in immunology 2021
Kidney Injury Molecule 1 (KIM-1): a Multifunctional Glycoprotein and Biological Marker (Review)
TA Karmakova, NS Sergeeva, KY Kanukoev, BY Alekseev, AD Kaprin
2021
KIM-1 mediates fatty acid uptake by renal tubular cells to promote progressive diabetic kidney disease
Y Mori, AK Ajay, JH Chang, S Mou, H Zhao, S Kishi, J Li, CR Brooks, S Xiao, HM Woo, VS Sabbisetti, SC Palmer, P Galichon, L Li, JM Henderson, VK Kuchroo, J Hawkins, T Ichimura, JV Bonventre
Cell Metabolism 2021
Having an Old Friend for Dinner: The Interplay between Apoptotic Cells and Efferocytes
AL Lam, B Heit
Cells 2021
A Review of Specific Biomarkers of Chronic Renal Injury and Their Potential Application in Nonclinical Safety Assessment Studies
LA Obert, SA Elmore, D Ennulat, KS Frazier
Toxicologic pathology 2021
Glycemic Variability and KIM-1–Induced Inflammation in the Diabetic Kidney
KR Tuttle, RZ Alicic
Diabetes 2021
Kidney injury molecule-1 inhibits metastasis of renal cell carcinoma
JC Lee, DM Yotis, JY Lee, MA Sarabusky, B Shrum, A Champagne, OZ Ismail, E Tutunea-Fatan, HS Leong, L Gunaratnam
Scientific Reports 2021
Renal Protective Effect of Beluga Lentil Pretreatment for Ischemia-Reperfusion Injury
S Lee, SY Chun, EH Lee, B Kim, BH Yoon, H Gil, DH Kim, BI Jang, DW Lee, ES Yoo, DJ Park, JN Lee, MH Han, BS Kim, PH Song, TG Kwon, YS Ha, D Monlezun
BioMed Research International 2021
Effect of embedded metal fragments on urinary metal levels and kidney biomarkers in the Sprague-Dawley rat
JF Hoffman, VB Vergara, AX Fan, JF Kalinich
Toxicology Reports 2021
Environmental circadian disruption suppresses rhythms in kidney function and accelerates excretion of renal injury markers in urine of male hypertensive rats
AM Hill, GR Crislip, A Stowie, I Ellis, A Ramsey, O Castanon-Cervantes, ML Gumz, AJ Davidson
American journal of physiology. Renal physiology 2021
Conceptual advances and evolving terminology in acute kidney disease
JA Kellum, C Ronco, R Bellomo
Nature Reviews Nephrology 2021
Anaesthesia-Induced Transcriptomic Changes in the Context of Renal Ischemia Uncovered by the Use of a Novel Clamping Device
C Verney, D Legouis, S Placier, T Migeon, P Bonnin, D Buob, J Hadchouel, P Galichon
International journal of molecular sciences 2021
Nephrotoxicity Assessment with Human Kidney Tubuloids using Spherical Nucleic Acid-Based mRNA Nanoflares
C Wiraja, Y Mori, T Ichimura, J Hwang, C Xu, JV Bonventre
Nano letters 2021
Abnormal development of cerebral arteries and veins in offspring of experimentally preeclamptic rats: Potential role in perinatal stroke
EE Whitaker, AC Johnson, JE Miller, DP Lindner, MJ Cipolla
Mechanisms of Ageing and Development 2021
Recombinant apoptosis inhibitor of macrophage protein reduces delayed graft function in a murine model of kidney transplantation
JY Lee, S Arumugarajah, D Lian, N Maehara, AR Haig, RS Suri, T Miyazaki, L Gunaratnam, P Mukhopadhyay
PloS one 2021
The Phosphatidylserine Receptor TIM-1 Enhances Authentic Chikungunya Virus Cell Entry
J Kirui, Y Abidine, A Lenman, K Islam, YD Gwon, L Lasswitz, M Evander, M Bally, G Gerold
Cells 2021
Selective depletion of a CD64-expressing phagocyte subset mediates protection against toxic kidney injury and failure
N Salei, X Ji, D Pakalniškytė, V Kuentzel, S Rambichler, N Li, M Moser, K Steiger, T Buch, HJ Anders, BU Schraml
Proceedings of the National Academy of Sciences 2021
Depletion of Toll-Like Receptor-9 Attenuates Renal Tubulointerstitial Fibrosis After Ischemia-Reperfusion Injury
H Zheng, Y Zhang, L Li, R Zhang, Z Luo, Z Yang, Y Ye, J He, Q Sun
Frontiers in Cell and Developmental Biology 2021
The Nephroprotective Properties of Extracellular Vesicles in Experimental Models of Chronic Kidney Disease: a Systematic Review
N Nowak, M Yamanouchi, E Satake
Stem Cell Reviews and Reports 2021
Approaches for Controlling Antibody-Mediated Allograft Rejection Through Targeting B Cells
Y Matsuda, T Watanabe, XK Li
Frontiers in immunology 2021
Kidney injury molecule-1: a novel entry factor for SARS-CoV-2
C Wan, C Zhang
Journal of Molecular Cell Biology 2021
Positive correlation between renal tubular flattening and renal tubular injury/interstitial fibrosis in murine kidney disease models
Y TAKAHASHI, M WATANABE, K HIURA, A ISOBE, H SASAKI, N SASAKI
Journal of Veterinary Medical Science 2021
CD36 Ectodomain Detects Apoptosis in Mammalian Cells
S Banesh, V Trivedi
Molecular Biotechnology 2021
Conserved and Distinct Elements of Phagocytosis in Human and C. elegans
S Lukácsi, Z Farkas, É Saskői, Z Bajtay, K Takács-Vellai
International journal of molecular sciences 2021
EphA2 Interacts with Tim-4 through Association between Its FN3 Domain and the IgV Domain of Tim-4
B Moon, S Yang, K Kim, J Lee, D Jeong, D Park
Cells 2021
Kidney Injury Molecule-1 and Periostin Urinary Excretion and Tissue Expression Levels and Association with Glomerular Disease Outcomes
Q Wu, JP Troost, T Dai, C Nast, S Eddy, B Wei, Y Wang, DS Gipson, KM Dell, KL Gibson, M Kretzler, S Adler
2021
Pairwise effects between lipid GWAS genes modulate lipid plasma levels and cellular uptake
M Zimoń, Y Huang, A Trasta, A Halavatyi, JZ Liu, CY Chen, P Blattmann, B Klaus, CD Whelan, D Sexton, S John, W Huber, EA Tsai, R Pepperkok, H Runz
Nature Communications 2021
Kidney injury molecule‑1 levels are associated with therapeutic outcomes and renal tubulointerstitial injury severity in idiopathic membranous nephropathy
Y Zhang, C Xiang, L Gong, Y Zhang, J Zhen, Z Hu, X Xiao
Experimental and therapeutic medicine 2021
High-Fat Diet-Induced Renal Proximal Tubular Inflammatory Injury: Emerging Risk Factor of Chronic Kidney Disease
S Chen, J Chen, S Li, F Guo, A Li, H Wu, J Chen, Q Pan, S Liao, H Liu, Q Pan
Frontiers in physiology 2021
Sweeping up dying cells during tissue injury
Arai Y, Yamaoka Y, Morioka S
Nephron 2021
Metabolic Consequences of Efferocytosis and its Impact on Atherosclerosis.
Yurdagul A Jr
Immunometabolism 2021
Human kidney injury molecule-1 as a urine biomarker differentiating urothelial and renal cell carcinoma
Białek Ł, Niemczyk M, Czerwińska K, Nowak M, Sadowska A, Borkowski T, Radziszewski P, Dobruch J, Kryst P, Poletajew S
Central European Journal of Urology 2021
Immunopathophysiology of trauma-related acute kidney injury
DA Messerer, R Halbgebauer, B Nilsson, H Pavenstädt, P Radermacher, M Huber-Lang
Nature Reviews Nephrology 2020
Protective Effects of Recombinant Human Soluble Thrombomodulin on Lipopolysaccharide-Induced Acute Kidney Injury
Y Nozaki, J Ri, K Sakai, K Niki, M Funauchi, I Matsumura
International journal of molecular sciences 2020
The Yin and Yang of Alarmins in Regulation of Acute Kidney Injury
V Sabapathy, R Venkatadri, M Dogan, R Sharma
Frontiers in Medicine 2020
Sodium Oxalate-Induced Acute Kidney Injury Associated With Glomerular and Tubulointerstitial Damage in Rats
L de Araújo, JM Costa-Pessoa, MC de Ponte, M Oliveira-Souza
Frontiers in physiology 2020
The role of phosphatidylserine recognition receptors in multiple biological functions
MB Naeini, V Bianconi, M Pirro, A Sahebkar
Cellular & Molecular Biology Letters 2020
Acute kidney injury and maladaptive tubular repair leading to renal fibrosis:
SM Yu, JV Bonventre
Current Opinion in Nephrology and Hypertension 2020
The Network of Inflammatory Mechanisms in Lupus Nephritis
Y Nozaki
Frontiers in Medicine 2020
Role of tumor cell senescence in non-professional phagocytosis and cell-in-cell structure formation
D Gottwald, F Putz, N Hohmann, M Büttner-Herold, M Hecht, R Fietkau, L Distel
2020
Nephrotoxicity of Herbal Medicine and Its Prevention
X Xu, R Zhu, J Ying, M Zhao, X Wu, G Cao, K Wang
Frontiers in pharmacology 2020
Phosphatidylethanolamine and Phosphatidylserine Synergize To Enhance GAS6/AXL-Mediated Virus Infection and Efferocytosis
L Zhang, AS Richard, CB Jackson, A Ojha, H Choe, RE Dutch
Journal of virology 2020
Predictive Nephrotoxicity Profiling of a Novel Antifungal Small Molecule in Comparison to Amphotericin B and Voriconazole
NS Udawatte, SW Kang, Y Wang, TV Arumugam, CJ Seneviratne
Frontiers in pharmacology 2020
Tim-4 functions as a scavenger receptor for phagocytosis of exogenous particles
C Min, J Park, G Kim, H Moon, SA Lee, D Kim, B Moon, S Yang, J Lee, K Kim, H Cho, J Park, DH Lee, G Lee, D Park
Cell Death and Disease 2020
Mapping and functional characterization of murine kidney injury molecule-1 proteolytic cleavage site
S Sriranganathan, E Tutunea-Fatan, A Abbasi, L Gunaratnam
Molecular and Cellular Biochemistry 2020
ROS-responsive chitosan-SS31 prodrug for AKI therapy via rapid distribution in the kidney and long-term retention in the renal tubule
D Liu, G Shu, F Jin, J Qi, X Xu, Y Du, H Yu, J Wang, M Sun, Y You, M Zhu, M Chen, L Zhu, Q Shen, X Ying, X Lou, S Jiang, Y Du
Science Advances 2020
Ethyl acetate extract of Ceiba pentandra (L.) Gaertn. reduces methotrexate-induced renal damage in rats via antioxidant, anti-inflammatory, and antiapoptotic actions
ME Abouelela, MA Orabi, RA Abdelhamid, MS Abdelkader, HR Madkor, FM Darwish, T Hatano, BE Elsadek
Journal of traditional and complementary medicine 2020
Dexmedetomidine Enhances Autophagy via α2-AR/AMPK/mTOR Pathway to Inhibit the Activation of NLRP3 Inflammasome and Subsequently Alleviates Lipopolysaccharide-Induced Acute Kidney Injury
T Yang, X Feng, Y Zhao, H Zhang, H Cui, M Wei, H Yang, H Fan
Frontiers in pharmacology 2020
Curcumin alleviates acute kidney injury in a dry‐heat environment by reducing oxidative stress and inflammation in a rat model
YH Zhao, CF Shen, GJ Wang, Y Kang, YH Song, JW Liu
Journal of Biochemical and Molecular Toxicology 2020
The Predictive Value of Urinary Kidney Injury Molecular 1 for the Diagnosis of Contrast-Induced Acute Kidney Injury after Cardiac Catheterization: A Meta-Analysis
Q Li, Y Huang, W Shang, Y Zhang, Y Liu, G Xu
Journal of Interventional Cardiology 2020
Novel renal biomarkers show that creatine supplementation is safe: a double-blind, placebo-controlled randomized clinical trial
J de Oliveira Vilar Neto, CA da Silva, GC Meneses, DV Pinto, LC Brito, SG da Cruz Fonseca, R de Sousa Alves, AM Martins, C de Oliveira Assumpção, ED Daher
Toxicology Research 2020
A review of the application of nanoparticles in the diagnosis and treatment of chronic kidney disease
Y Ma, F Cai, Y Li, J Chen, F Han, W Lin
Bioactive Materials 2020
Roles Played by Biomarkers of Kidney Injury in Patients with Upper Urinary Tract Obstruction
S Washino, K Hosohata, T Miyagawa
International journal of molecular sciences 2020
Effects of pneumoperitoneum with carbon dioxide on renal and hepatic functions in rats
T Bilgic, F Narter
VIDEOSURGERY MINIINV 2020
Proximal tubule ATR regulates DNA repair to prevent maladaptive renal injury responses
Seiji Kishi, Craig R. Brooks, Kensei Taguchi, Takaharu Ichimura, Yutaro Mori, Akinwande Akinfolarin, Navin Gupta, Pierre Galichon, Bertha C Elias, Tomohisa Suzuki, Qian Wang, Leslie Gewin, Ryuji Morizane, Joseph V. Bonventre
Journal of Clinical Investigation 2019
FoxM1 drives proximal tubule proliferation during repair from acute ischemic kidney injury
Monica Chang-Panesso, Farid F Kadyrov, Matthew, A Lalli, Haojia Wu, Shiyo Ikeda, Eirini Kefaloyianni, Mai M. Abdelmageed, Andreas Herrlich, Akio Kobayashi, Benjamin D. Humphreys
Journal of Clinical Investigation 2019
MicroRNA-146a-deficient mice develop immune complex glomerulonephritis
L Amrouche, S You, V Sauvaget, V Manda, B Lamarthée, G Desbuissons, C Tinel, M Rabant, C Nguyen, P Isnard, M Burtin, N Charles, C Legendre, F Terzi, D Anglicheau
Scientific Reports 2019
Efferocytosis in health and disease
AC Doran, A Yurdagul, I Tabas
Nature Reviews Immunology 2019
Why Have Detection, Understanding and Management of Kidney Hypoxic Injury Lagged Behind those for the Heart?
Z Abassi, S Rosen, S Lamothe, SN Heyman
Journal of Clinical Medicine 2019
Biomarkers of Drug-Induced Kidney Toxicity:
BR Griffin, S Faubel, CL Edelstein
Therapeutic Drug Monitoring 2019
TIM-3 and TIM-1 Could Regulate Decidual γδ TCR Bright T Cells during Murine Pregnancy
J Nörenberg, M Meggyes, P Jakso, E Miko, A Barakonyi
Journal of Immunology Research 2019
Gentamicin induced acute renal damage and its evaluation using urinary biomarkers in rats
V Udupa, V Prakash
Toxicology Reports 2019
Characterization of the Filovirus-Resistant Cell Line SH-SY5Y Reveals Redundant Role of Cell Surface Entry Factors
F Zapatero-Belinchón, E Dietzel, O Dolnik, K Döhner, R Costa, B Hertel, B Veselkova, J Kirui, A Klintworth, M Manns, S Pöhlmann, T Pietschmann, T Krey, S Ciesek, G Gerold, B Sodeik, S Becker, T von Hahn
Viruses 2019
Nifedipine Modulates Renal Lipogenesis via the AMPK-SREBP Transcriptional Pathway
YC Lin, MS Wu, YF Lin, CR Chen, CY Chen, CJ Chen, CC Shen, KC Chen, CC Peng
International journal of molecular sciences 2019
Kidney injury molecule-1 expression predicts structural damage and outcome in histological acute tubular injury
J Cai, X Jiao, W Luo, J Chen, X Xu, Y Fang, X Ding, X Yu
Renal Failure 2019
In Vivo Comparison of the Phenotypic Aspects and Molecular Mechanisms of Two Nephrotoxic Agents, Sodium Fluoride and Uranyl Nitrate
A Bontemps, L Conquet, C Elie, V Magneron, C Gloaguen, D Kereselidze, K Tack, O Barbier, Y Guéguen
International journal of environmental research and public health 2019
Translational Assessment of Drug‐Induced Proximal Tubule Injury Using a Kidney Microphysiological System
C Maass, NB Sorensen, J Himmelfarb, EJ Kelly, CL Stokes, M Cirit
CPT Pharmacometrics Syst. Pharmacol. 2019
Evaluation of kidney injury molecule-1 as a disease progression biomarker in diabetic nephropathy
FA Khan, SS Fatima, GM Khan, S Shahid
Pakistan Journal of Medical Sciences 2019
TIM-1 serves as a receptor for Ebola virus in vivo, enhancing viremia and pathogenesis
B Brunton, K Rogers, EK Phillips, RB Brouillette, R Bouls, NS Butler, W Maury, MR Holbrook
PLoS neglected tropical diseases 2019
Non-professional phagocytosis: a general feature of normal tissue cells
JC Seeberg, M Loibl, F Moser, M Schwegler, M Büttner-Herold, C Daniel, FB Engel, A Hartmann, U Schlötzer-Schrehardt, M Goppelt-Struebe, V Schellerer, E Naschberger, I Ganzleben, L Heinzerling, R Fietkau, LV Distel
Scientific Reports 2019
Kidney Injury Molecule-1 Is Upregulated in Renal Lipotoxicity and Mediates Palmitate-Induced Tubular Cell Injury and Inflammatory Response
X Zhao, X Chen, Y Zhang, J George, A Cobbs, G Wang, L Li, N Emmett
International journal of molecular sciences 2019
Zika Virus Infection Induces Acute Kidney Injury Through Activating NLRP3 Inflammasome Via Suppressing Bcl-2
T Liu, L Tang, H Tang, J Pu, S Gong, D Fang, H Zhang, YP Li, X Zhu, W Wang, M Wu, Y Liao, C Li, H Zhou,
Frontiers in immunology 2019
Renovascular disease induces mitochondrial damage in swine scattered tubular cells
AA Nargesi, XY Zhu, SM Conley, JR Woollard, IM Saadiq, LO Lerman, A Eirin
American journal of physiology. Renal physiology 2019
Neonatal obstructive nephropathy induces necroptosis and necroinflammation
B Popper, MT Rammer, M Gasparitsch, T Singer, U Keller, Y Döring, B Lange-Sperandio
Scientific Reports 2019
Diagnostic role of kidney injury molecule-1 in renal cell carcinoma
KJ Zhang, GD Wilson, S Kara, A Majeske, PL Zhang, JM Hafron
International Urology and Nephrology 2019
Kidney injury molecule-1, a sensitive and specific marker for identifying acute proximal tubular injury, can be used to predict renal functional recovery in native renal biopsies
W Yin, T Kumar, Z Lai, X Zeng, HD Kanaan, W Li, PL Zhang
International Urology and Nephrology 2019
Dynamic variation of kidney injury molecule-1 mRNA and protein expression in blood and urine of renal transplant recipients: a cohort study
SK Shahbaz, F Pourrezagholi, M Nafar, P Ahmadpoor, M Barabadi, F Foroughi, M Hosseinzadeh, MS Yekaninejad, A Amirzargar
Clinical and Experimental Nephrology 2019
Kidney Injury Biomarkers in an Academic Hospital Setting: Where Are We Now?
van Duijl TT, Ruhaak LR, de Fijter JW, Cobbaert CM
The Clinical Biochemist Reviews 2019
Human Kidney on a Chip Assessment of Polymyxin Antibiotic Nephrotoxicity
Elijah Weber, Kevin A Lidberg, lu wang, Theo K Bammler, James MacDonald, Mavis Jiarong Li, Michelle Redhair, William M. Atkins, Cecilia K Tran, Kelly M. Hines, Josi Herron, Libin Xu, Maria B. Monteiro, Susanne Ramm, Vishal Vaidya, Martti Vaara, Timo Vaara, Jonathan Himmelfarb, Edward J. Kelly
JCI Insight 2018
Clearance of Apoptotic Cells by Tissue Epithelia: A Putative Role for Hepatocytes in Liver Efferocytosis
SP Davies, GM Reynolds, Z Stamataki
Frontiers in immunology 2018
TIM-1 Mediates Dystroglycan-Independent Entry of Lassa Virus
RB Brouillette, EK Phillips, R Patel, W Mahauad-Fernandez, S Moller-Tank, KJ Rogers, JA Dillard, AL Cooney, L Martinez-Sobrido, C Okeoma, W Maury, RM Sandri-Goldin
Journal of virology 2018
Immune mechanisms in the different phases of acute tubular necrosis
F Kundert, L Platen, T Iwakura, Z Zhao, JA Marschner, HJ Anders
Kidney Research and Clinical Practice 2018
Meis1 is specifically upregulated in kidney myofibroblasts during aging and injury but is not required for kidney homeostasis or fibrotic response
M Chang-Panesso, FF Kadyrov, FG Machado, A Kumar, BD Humphreys
American journal of physiology. Renal physiology 2018
Uromodulin deficiency alters tubular injury and interstitial inflammation but not fibrosis in experimental obstructive nephropathy
O Maydan, PG McDade, Y Liu, XR Wu, DG Matsell, AA Eddy
Physiological Reports 2018
HIV internalization into oral and genital epithelial cells by endocytosis and macropinocytosis leads to viral sequestration in the vesicles
A Yasen, R Herrera, K Rosbe, K Lien, SM Tugizov
Virology 2018
Tctex-1, a novel interaction partner of Kidney Injury Molecule-1, is required for efferocytosis
OZ Ismail, S Sriranganathan, X Zhang, JV Bonventre, AS Zervos, L Gunaratnam
Journal of Cellular Physiology 2018
Urinary biomarkers predict advanced acute kidney injury after cardiovascular surgery
JJ Wang, NH Chi, TM Huang, R Connolly, LW Chen, SC Chueh, WC Kan, CC Lai, VC Wu, JT Fang, TS Chu, KD Wu
Critical Care 2018
Advances in predictive in vitro models of drug-induced nephrotoxicity
JY Soo, J Jansen, R Masereeuw, MH Little
Nature Reviews Nephrology 2018
Markers of early progressive renal decline in type 2 diabetes suggest different implications for etiological studies and prognostic tests development
N Nowak, J Skupien, AM Smiles, M Yamanouchi, MA Niewczas, AT Galecki, KL Duffin, MD Breyer, N Pullen, JV Bonventre, AS Krolewski
Kidney International 2018
Dan-Lou Prescription Inhibits Foam Cell Formation Induced by ox-LDL via the TLR4/NF-κB and PPARγ Signaling Pathways
LN Gao, X Zhou, YR Lu, K Li, S Gao, CQ Yu, YL Cui
Frontiers in physiology 2018
Kidney Injury Molecule-1 Identifies Antemortem Injury in Postmortem Adult and Fetal Kidney
W Yin, PL Zhang, J Macknis, F Lin, JV Bonventre
American journal of physiology. Renal physiology 2018
Independent modes of disease repair by AIM protein distinguished in AIM-felinized mice
R Sugisawa, G Komatsu, E Hiramoto, N Takeda, K Yamamura, S Arai, T Miyazaki
Scientific Reports 2018
Urinary Tubular Injury Biomarkers Are Associated With ESRD and Death in the REGARDS Study
RF Dubin, S Judd, R Scherzer, M Shlipak, DG Warnock, M Cushman, M Sarnak, C Parikh, M Bennett, N Powe, CA Peralta
Kidney International Reports 2018
Urinary Biomarkers of Aminoglycoside-Induced Nephrotoxicity in Cystic Fibrosis: Kidney Injury Molecule-1 and Neutrophil Gelatinase-Associated Lipocalin
SJ McWilliam, DJ Antoine, AL Jorgensen, RL Smyth, M Pirmohamed
Scientific Reports 2018
Twenty-four-hour normothermic perfusion of discarded human kidneys with urine recirculation
A Weissenbacher, LL Faro, O Boubriak, MF Soares, IS Roberts, JP Hunter, D Voyce, N Mikov, A Cook, RJ Ploeg, CC Coussios, PJ Friend
American Journal of Transplantation 2018
Identification of Urinary Activin A as a Novel Biomarker Reflecting the Severity of Acute Kidney Injury
S Takahashi, M Nakasatomi, Y Takei, H Ikeuchi, T Sakairi, Y Kaneko, K Hiromura, Y Nojima, A Maeshima
Scientific Reports 2018
Measurement of urinary biomarkers in a case of tubulointerstitial nephritis and uveitis syndrome during glucocorticoid treatment
M Sugiyama
CEN Case Reports 2018
Efferocytosis and autoimmune disease
M Kawano, S Nagata
International Immunology 2018
Associations of Circulating Protein Levels With Lipid Fractions in the General Population
SM Figarska, S Gustafsson, J Sundström, J Ärnlöv, A Mälarstig, S Elmståhl, T Fall, L Lind, E Ingelsson
Arteriosclerosis, thrombosis, and vascular biology 2018
Technology Transfer of the Microphysiological Systems: A Case Study of the Human Proximal Tubule Tissue Chip
C Sakolish, EJ Weber, EJ Kelly, J Himmelfarb, R Mouneimne, FA Grimm, JS House, T Wade, A Han, WA Chiu, I Rusyn
Scientific Reports 2018
A scavenging system against internal pathogens promoted by the circulating protein apoptosis inhibitor of macrophage (AIM)
S Arai, T Miyazaki
Seminars in Immunopathology 2018
Reconstructing the Human Renal Vascular-Tubular Unit In Vitro
SG Rayner, KT Phong, J Xue, D Lih, SJ Shankland, EJ Kelly, J Himmelfarb, Y Zheng
Advanced Healthcare Materials 2018
Circulating Biomarker Levels in Patients With Stage 5 Chronic Kidney Disease With Respect to Neurovascular Diseases
J Lee, R McMillan, L Skiadopoulos, V Bansal, J Biller, D Hoppensteadt, J Fareed
Clinical and Applied Thrombosis/Hemostasis 2018
Quantification of Efferocytosis by Single-cell Fluorescence Microscopy
K Taruc, C Yin, DG Wootton, B Heit
Journal of visualized experiments : JoVE 2018
A specific immunoassay for detection of feline kidney injury molecule 1
Bland SK, Clark ME, Côté O, Bienzle D
Journal of Feline Medicine & Surgery 2018
Apoptosis inhibitor of macrophage ameliorates fungus-induced peritoneal injury model in mice
T Tomita, S Arai, K Kitada, M Mizuno, Y Suzuki, F Sakata, D Nakano, E Hiramoto, Y Takei, S Maruyama, A Nishiyama, S Matsuo, T Miyazaki, Y Ito
Scientific Reports 2017
Engulfment signals and the phagocytic machinery for apoptotic cell clearance
SY Park, IS Kim
Experimental & molecular medicine 2017
Efferocytosis Signaling in the Regulation of Macrophage Inflammatory Responses
MR Elliott, KM Koster, PS Murphy
Journal of immunology (Baltimore, Md. : 1950) 2017
The Tubulointerstitial Pathophysiology of Progressive Kidney Disease
HW Schnaper
Advances in Chronic Kidney Disease 2017
Novel Biomarkers in the Diagnosis of Chronic Kidney Disease and the Prediction of Its Outcome
J Rysz, A Gluba-Brzózka, B Franczyk, Z Jabłonowski, A Ciałkowska-Rysz
International journal of molecular sciences 2017
CD74 Deficiency Mitigates Systemic Lupus Erythematosus-like Autoimmunity and Pathological Findings in Mice
Yi Zhou, Huimei Chen, Li Liu, Xueqing Yu, Galina K Sukhova, Min Yang, Lijun Zhang, Vasileios C Kyttaris, George C Tsokos, Isaac E Stillman, Takaharu Ichimura, Joseph V Bonventre, Peter Libby, Guo-Ping Shi
Journal of immunology (Baltimore, Md. : 1950) 2017
Extracellular Signal–Regulated Kinase 1/2 Regulates Mouse Kidney Injury Molecule-1 Expression Physiologically and Following Ischemic and Septic Renal Injury
JB Collier, RG Schnellmann
The Journal of pharmacology and experimental therapeutics 2017
Fibrotic Changes Mediating Acute Kidney Injury to Chronic Kidney Disease Transition
EÓ hAinmhire, BD Humphreys
Nephron. Clinical practice 2017
Urinary protein biomarkers of kidney injury in patients receiving cisplatin chemotherapy
B George, MS Joy, LM Aleksunes
Experimental biology and medicine (Maywood, N.J.) 2017
Isolation and characterization of urinary extracellular vesicles: implications for biomarker discovery
ML Merchant, IM Rood, JK Deegens, JB Klein
Nature Reviews Nephrology 2017
Detection of Drug-Induced Acute Kidney Injury in Humans Using Urinary KIM-1, miR-21, -200c, and -423
M Pavkovic, C Robinson-Cohen, AS Chua, O Nicoara, M Cárdenas-González, V Bijol, K Ramachandran, L Hampson, M Pirmohamed, DJ Antoine, G Frendl, J Himmelfarb, SS Waikar, VS Vaidya
Toxicological Sciences 2016
Extracellular Vesicles Exploit Viral Entry Routes for Cargo Delivery
HM van Dongen, N Masoumi, KW Witwer, DM Pegtel
Microbiology and molecular biology reviews : MMBR 2016
Biomarkers in acute kidney injury - pathophysiological basis and clinical performance
EV Schrezenmeier, J Barasch, K Budde, T Westhoff, KM Schmidt-Ott
Acta physiologica (Oxford, England) 2016
The potential use of biomarkers in predicting contrast-induced acute kidney injury
M Andreucci, T Faga, E Riccio, M Sabbatini, A Pisani, A Michael
International journal of nephrology and renovascular disease 2016
Macrophages redirect phagocytosis by non-professional phagocytes and influence inflammation
CZ Han, IJ Juncadella, JM Kinchen, MW Buckley, AL Klibanov, K Dryden, S Onengut-Gumuscu, U Erdbrügger, SD Turner, YM Shim, KS Tung, KS Ravichandran
Nature 2016
The proximal tubule is the primary target of injury and progression of kidney disease: role of the glomerulotubular junction
RL Chevalier
American journal of physiology. Renal physiology 2016
Renal-targeting triptolide-glucosamine conjugate exhibits lower toxicity and superior efficacy in attenuation of ischemia/reperfusion renal injury in rats
Y Fu, Q Lin, T Gong, X Sun, Z Zhang
Acta Pharmacologica Sinica 2016
Kidney injury molecule-1 (KIM-1) mediates renal epithelial cell repair via ERK MAPK signaling pathway
Z Zhang, CX Cai
Molecular and Cellular Biochemistry 2016
Acute kidney injury and chronic kidney disease: From the laboratory to the clinic
DA Ferenbach, JV Bonventre
Néphrologie & Thérapeutique 2016
Environmental exposure to arsenic and chromium in children is associated with kidney injury molecule-1
M Cárdenas-González, C Osorio-Yáñez, O Gaspar-Ramírez, M Pavković, A Ochoa-Martínez, D López-Ventura, M Medeiros, OC Barbier, IN Pérez-Maldonado, VS Sabbisetti, JV Bonventre, VS Vaidya
Environmental Research 2016
Apoptosis inhibitor of macrophage protein enhances intraluminal debris clearance and ameliorates acute kidney injury in mice
S Arai, K Kitada, T Yamazaki, R Takai, X Zhang, Y Tsugawa, R Sugisawa, A Matsumoto, M Mori, Y Yoshihara, K Doi, N Maehara, S Kusunoki, A Takahata, E Noiri, Y Suzuki, N Yahagi, A Nishiyama, L Gunaratnam, T Takano, T Miyazaki
Nature Medicine 2016
Development of a microphysiological model of human kidney proximal tubule function
EJ Weber, A Chapron, BD Chapron, JL Voellinger, KA Lidberg, CK Yeung, Z Wang, Y Yamaura, DW Hailey, T Neumann, DD Shen, KE Thummel, KA Muczynski, J Himmelfarb, EJ Kelly
Kidney International 2016
Urinary Biomarkers KIM-1 and NGAL for Detection of Chronic Kidney Disease of Uncertain Etiology (CKDu) among Agricultural Communities in Sri Lanka
PM de Silva, KS Abdul, EM Eakanayake, SS Jayasinghe, C Jayasumana, HB Asanthi, HS Perera, GG Chaminda, EP Chandana, SH Siribaddana, JM Vinetz
PLoS neglected tropical diseases 2016
Aminoglycoside-induced nephrotoxicity in children
SJ McWilliam, DJ Antoine, RL Smyth, M Pirmohamed
Pediatric Nephrology 2016
A proteolytic modification of AIM promotes its renal excretion
T Yamazaki, R Sugisawa, E Hiramoto, R Takai, A Matsumoto, Y Senda, K Nakashima, PS Nelson, JM Lucas, A Morgan, Z Li, K Yamamura, S Arai, T Miyazaki
Scientific Reports 2016
A kidney injury molecule-1 (Kim-1) gene reporter in a mouse artificial chromosome: the responsiveness to cisplatin toxicity in immortalized mouse kidney S3 cells: Kim-1 reporter for cisplatin toxicity
K Kokura, Y Kuromi, T Endo, N Anzai, Y Kazuki, M Oshimura, T Ohbayashi
The Journal of Gene Medicine 2016
Rab17 mediates differential antigen sorting following efferocytosis and phagocytosis
C Yin, Y Kim, D Argintaru, B Heit
Cell Death and Disease 2016
Impact of feline AIM on the susceptibility of cats to renal disease
R Sugisawa, E Hiramoto, S Matsuoka, S Iwai, R Takai, T Yamazaki, N Mori, Y Okada, N Takeda, K Yamamura, T Arai, S Arai, T Miyazaki
Scientific Reports 2016
KIM-1/TIM-1 mediated-phagocytosis reduces acute injury to the kidney
Li Yang, Craig Brooks, Sheng Xiao, Venkata Sabbisetti, Melissa Yeung, Li-Li Hsiao, Takaharu Ichimura, Vijay Kuchroo, Joseph V. Bonventre
Journal of Clinical Investigation 2015
Severity and Frequency of Proximal Tubule Injury Determines Renal Prognosis
K Takaori, J Nakamura, S Yamamoto, H Nakata, Y Sato, M Takase, M Nameta, T Yamamoto, AN Economides, K Kohno, H Haga, K Sharma, M Yanagita
Journal of the American Society of Nephrology : JASN 2015
TIM-1 Signaling Is Required for Maintenance and Induction of Regulatory B Cells: Breg Induction Requires TIM-1 Signaling
MY Yeung, Q Ding, CR Brooks, S Xiao, CJ Workman, DA Vignali, T Ueno, RF Padera, VK Kuchroo, N Najafian, DM Rothstein
American Journal of Transplantation 2015
Cardiorenal Syndrome Type 1: Activation of Dual Apoptotic Pathways
S Pastori, GM Virz, A Brocca, M Cal, V Cantaluppi, C Castellani, M Fedrigo, G Thiene, ML Valente, A Angelini, G Vescovo, C Ronco
Cardiorenal Medicine 2015
Subclinical kidney injury before and 1 year after bariatric surgery among adolescents with severe obesity: Subclinical Kidney Injury and Severe Obesity
N Xiao, P Devarajan, TH Inge, TM Jenkins, M Bennett, MM Mitsnefes
Obesity 2015
Urine Injury Biomarkers and Risk of Adverse Outcomes in Recipients of Prevalent Kidney Transplants: The Folic Acid for Vascular Outcome Reduction in Transplantation Trial
N Bansal, MA Carpenter, DE Weiner, AS Levey, M Pfeffer, JW Kusek, J Cai, LG Hunsicker, M Park, M Bennett, KD Liu, C Hsu
Journal of the American Society of Nephrology : JASN 2015
Apoptotic cell recognition receptors and scavenger receptors
KK Penberthy, KS Ravichandran
Immunological Reviews 2015
The Macrophage Phagocytic Receptor CD36 Promotes Fibrogenic Pathways on Removal of Apoptotic Cells during Chronic Kidney Injury
S Pennathur, K Pasichnyk, NM Bahrami, L Zeng, M Febbraio, I Yamaguchi, DM Okamura
The American Journal of Pathology 2015
Mechanisms of maladaptive repair after AKI leading to accelerated kidney ageing and CKD
DA Ferenbach, JV Bonventre
Nature Reviews Nephrology 2015
MG53-mediated cell membrane repair protects against acute kidney injury
P Duann, H Li, P Lin, T Tan, Z Wang, K Chen, X Zhou, K Gumpper, H Zhu, T Ludwig, PJ Mohler, B Rovin, WT Abraham, C Zeng, J Ma
Science Translational Medicine 2015
Kidney injury molecule-1 expression in human kidney transplants with interstitial fibrosis and tubular atrophy
AL Nogare, FV Veronese, VN Carpio, RM Montenegro, JA Pedroso, KL Pegas, LF Gonçalves, RC Manfro
BMC Nephrology 2015
No increase in Kidney Injury Molecule-1 and Neutrophil Gelatinase-Associated Lipocalin excretion following intravenous contrast enhanced-CT
J Kooiman, WR van de Peppel, YW Sijpkens, HF Brulez, PM de Vries, MA Nicolaie, H Putter, MV Huisman, W der Kooij, C Kooten, TJ Rabelink
European Radiology 2015
Chronic Kidney Disease Influences Multiple Systems: Describing the Relationship between Oxidative Stress, Inflammation, Kidney Damage, and Concomitant Disease
PS Tucker, AT Scanlan, VJ Dalbo
Oxidative medicine and cellular longevity 2015
Tim-1 Is Essential for Induction and Maintenance of IL-10 in Regulatory B Cells and Their Regulation of Tissue Inflammation
S Xiao, CR Brooks, RA Sobel, VK Kuchroo
Journal of immunology (Baltimore, Md. : 1950) 2015
Proximal Tubular Injury in Medullary Rays Is an Early Sign of Acute Tacrolimus Nephrotoxicity
D Cosner, X Zeng, PL Zhang
Journal of Transplantation 2015
Safety and Efficacy Endpoints for Mesenchymal Stromal Cell Therapy in Renal Transplant Recipients
JR Bank, TJ Rabelink, JW de Fijter, ME Reinders
Journal of Immunology Research 2015
Interaction between TIM-1 and NPC1 Is Important for Cellular Entry of Ebola Virus
M Kuroda, D Fujikura, A Nanbo, A Marzi, O Noyori, M Kajihara, J Maruyama, K Matsuno, H Miyamoto, R Yoshida, H Feldmann, A Takada, A García-Sastre
Journal of virology 2015
Effects of carnitine on oxidative stress response to intravenous iron administration to patients with CKD: impact of haptoglobin phenotype
Z Armaly, AA el Qader, A Jabbour, K Hassan, R Ramadan, A Bowirrat, B Bisharat
BMC Nephrology 2015
Kidney Injury Molecule-1 Enhances Endocytosis of Albumin in Renal Proximal Tubular Cells: KIM-1 EXPRESSION AND TUBULAR ALBUMIN HANDLING
X Zhao, C Jiang, R Olufade, D Liu, N Emmett
Journal of Cellular Physiology 2015
Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids
Benjamin S Freedman, Craig R Brooks, Albert Q Lam, Hongxia Fu, Ryuji Morizane, Vishesh Agrawal, Abdelaziz F Saad, Michelle K Li, Michael R Hughes, Ryan Vander Werff, Derek T Peters, Junjie Lu, Anna Baccei, Andrew M Siedlecki, M Todd Valerius, Kiran Musunuru, Kelly M McNagny, Theodore I Steinman, Jing Zhou, Paul H Lerou, Joseph V Bonventre
Nature Communications 2015
KIM-1-/TIM-1-mediated phagocytosis links ATG5-/ULK1-dependent clearance of apoptotic cells to antigen presentation
CR Brooks, MY Yeung, YS Brooks, H Chen, T Ichimura, JM Henderson, JV Bonventre
The EMBO Journal 2015
G protein α 12 (Gα 12 ) is a negative regulator of kidney injury molecule-1-mediated efferocytosis
OZ Ismail, X Zhang, JV Bonventre, L Gunaratnam
American journal of physiology. Renal physiology 2015
Mammalian Target of Rapamycin Mediates Kidney Injury Molecule 1-Dependent Tubule Injury in a Surrogate Model
W Yin, SM Naini, G Chen, DM Hentschel, BD Humphreys, JV Bonventre
Journal of the American Society of Nephrology : JASN 2015
Evaluation of cystatin C as an early biomarker of cadmium nephrotoxicity in the rat
WC Prozialeck, A VanDreel, CD Ackerman, I Stock, A Papaeliou, C Yasmine, K Wilson, PC Lamar, VL Sears, JZ Gasiorowski, KM DiNovo, VS Vaidya, JR Edwards
BioMetals 2015
Kidney Injury Molecule-1 and Cardiovascular Diseases: From Basic Science to Clinical Practice
B Medić, B Rovčanin, GB Jovanović, S Radojević-Škodrić, M Prostran
BioMed Research International 2015
Modeling Kidney Disease with iPS Cells
Freedman
Biomarker insights 2015
No Effect of Remote Ischemic Conditioning Strategies on Recovery from Renal Ischemia-Reperfusion Injury and Protective Molecular Mediators
C Kierulf-Lassen, ML Kristensen, H Birn, B Jespersen, R Nørregaard, F Gallyas
PloS one 2015
Efferocytosis creates a tumor microenvironment supportive of tumor survival and metastasis.
Vaught DB, Stanford JC, Cook RS
Cancer Cell & Microenvironment 2015
KIM-1/TIM-1 in proximal tubular cell immune response
Brooks CR, Bonventre JV
Oncotarget 2015
Kidney fibrosis: recent advances
Jeremy Duffield
Journal of Clinical Investigation 2014
A basic science view of acute kidney injury biomarkers
JR Charlton, D Portilla, MD Okusa
Nephrology Dialysis Transplantation 2014
Biomarkers of AKI: A Review of Mechanistic Relevance and Potential Therapeutic Implications
JL Alge, JM Arthur
Clinical journal of the American Society of Nephrology : CJASN 2014
Effects of cell-type-specific expression of a pan-caspase inhibitor on renal fibrogenesis
T Inoue, T Kusano, K Tomori, H Nakamoto, H Suzuki, H Okada
Clinical and Experimental Nephrology 2014
Cilostazol Renoprotective Effect: Modulation of PPAR-γ, NGAL, KIM-1 and IL-18 Underlies Its Novel Effect in a Model of Ischemia-Reperfusion
D Ragab, DM Abdallah, HS El-Abhar, G Drossopoulou
PloS one 2014
Albumin and glycated albumin activate KIM-1 release in tubular epithelial cells through distinct kinetics and mechanisms
AI Lim, LY Chan, SC Tang, KN Lai, JC Leung
Inflammation Research 2014
How the Innate Immune System Senses Trouble and Causes Trouble
T Hato, PC Dagher
Clinical journal of the American Society of Nephrology : CJASN 2014
Predictive value of urinary and serum biomarkers in young children with febrile urinary tract infections
HE Yim, H Yim, ES Bae, SU Woo, KH Yoo
Pediatric Nephrology 2014
Emerging Biomarkers and Metabolomics for Assessing Toxic Nephropathy and Acute Kidney Injury (AKI) in Neonatology
M Mussap, A Noto, V Fanos, JN van Anker
BioMed Research International 2014
Defining the Acute Kidney Injury and Repair Transcriptome
S Kumar, J Liu, AP McMahon
Seminars in Nephrology 2014
Acute pretreatment with chloroquine attenuates renal I/R injury in rats
Z Todorovic, B Medic, G Basta-Jovanovic, SR Skodric, R Stojanovic, B Rovcanin, M Prostran
PloS one 2014
Kidney injury molecule-1 is involved in the chemotactic migration of mesenchymal stem cells
KM Park, HS Nam, PK Teotia, KH Hussein, SH Hong, JI Yun, HM Woo
In vitro cellular & developmental biology. Animal 2014
Urinary kidney injury molecule-1 is related to pathologic involvement in IgA nephropathy with normotension, normal renal function and mild proteinuria
P Xu, L Wei, W Shang, S Tian, D Gu, T Yan, S Lin
BMC Nephrology 2014
The Hemodynamic and Nonhemodynamic Crosstalk in Cardiorenal Syndrome Type 1
GM Virzì, A Clementi, A Brocca, M Cal, G Vescovo, A Granata, C Ronco
Cardiorenal Medicine 2014
Phosphatidylserine receptors: Enhancers of enveloped virus entry and infection
S Moller-Tank, W Maury
Virology 2014
Characterization of Kidney Injury Molecule-1 in Cats
SK Bland, O Côté, ME Clark, J DeLay, D Bienzle
Journal of Veterinary Internal Medicine 2014
Use of urinary renal biomarkers to evaluate the nephrotoxic effects of melamine or cyanuric acid in non-pregnant and pregnant rats
OJ Bandele, CB Stine, M Ferguson, T Black, N Olejnik, Z Keltner, ER Evans, TC Crosby, R Reimschuessel, RL Sprando
Food and Chemical Toxicology 2014
Erythrophagocytosis of Lead-Exposed Erythrocytes by Renal Tubular Cells: Possible Role in Lead-Induced Nephrotoxicity
SY Kwon, ON Bae, JY Noh, K Kim, S Kang, YJ Shin, KM Lim, JH Chung
Environmental Health Perspectives 2014
Accelerated receptor shedding inhibits kidney injury molecule-1 (KIM-1)-mediated efferocytosis
R Gandhi, J Yi, J Ha, H Shi, O Ismail, S Nathoo, JV Bonventre, X Zhang, L Gunaratnam
American journal of physiology. Renal physiology 2014
Galectin-9 Signaling through TIM-3 Is Involved in Neutrophil-Mediated Gram-Negative Bacterial Killing: An Effect Abrogated within the Cystic Fibrosis Lung
I Vega-Carrascal, DA Bergin, OJ McElvaney, C McCarthy, N Banville, K Pohl, M Hirashima, VK Kuchroo, EP Reeves, NG McElvaney
Journal of immunology (Baltimore, Md. : 1950) 2014
Chronic Epithelial Kidney Injury Molecule-1 Expression in Mice Causes Inflammation, Fibrosis and Kidney Failure
Benjamin D. Humphreys, Fengfeng Xu, Venkata Sabbisetti, Ivica Grgic, Said Naini, NingNing Wang, Guochun Chen, Sheng Xiao, Dhruti Patel, Joel Henderson, Takaharu Ichimura, Shan Mou, Savuth Soeung, Andrew McMahon, Vijay Kuchroo, Joseph V. Bonventre
Journal of Clinical Investigation 2013
l-Citrulline Protects from Kidney Damage in Type 1 Diabetic Mice
MJ Romero, L Yao, S Sridhar, A Bhatta, H Dou, G Ramesh, MW Brands, DM Pollock, RB Caldwell, SD Cederbaum, CA Head, Z Bagi, R Lucas, RW Caldwell
Frontiers in immunology 2013
New Biomarkers for the Quick Detection of Acute Kidney Injury
A Simsek, V Tugcu, AI Tasci
ISRN Nephrology 2013
Clinical Application Neutrophil Gelatinase-Associated Lipocalin and Kidney Injury Molecule-1 as Indicators of Inflammation Persistence and Acute Kidney Injury in Children with Urinary Tract Infection
S Petrovic, N Bogavac-Stanojevic, A Peco-Antic, I Ivanisevic, J Kotur-Stevuljevic, D Paripovic, M Sopic, Z Jelic-Ivanovic
BioMed Research International 2013
Role of New Biomarkers: Functional and Structural Damage
E Tsigou, V Psallida, C Demponeras, E Boutzouka, G Baltopoulos
Critical care research and practice 2013
TLR-2/TLR-4 TREM-1 Signaling Pathway Is Dispensable in Inflammatory Myeloid Cells during Sterile Kidney Injury
G Campanholle, K Mittelsteadt, S Nakagawa, A Kobayashi, SL Lin, SA Gharib, JW Heinecke, JA Hamerman, WA Altemeier, JS Duffield
PloS one 2013
Sisters in arms: myeloid and tubular epithelial cells shape renal innate immunity
T Hato, TM El-Achkar, PC Dagher
American journal of physiology. Renal physiology 2013
A Bioinformatics Approach Identifies Signal Transducer and Activator of Transcription-3 and Checkpoint Kinase 1 as Upstream Regulators of Kidney Injury Molecule-1 after Kidney Injury
AK Ajay, TM Kim, V Ramirez-Gonzalez, PJ Park, DA Frank, VS Vaidya
Journal of the American Society of Nephrology : JASN 2013
Bilirubin attenuates the renal tubular injury by inhibition of oxidative stress and apoptosis
SW Oh, ES Lee, S Kim, KY Na, DW Chae, S Kim, HJ Chin
BMC Nephrology 2013
Scavenger receptors in homeostasis and immunity
J Canton, D Neculai, S Grinstein
Nature Reviews Immunology 2013
Cellular Factors Implicated in Filovirus Entry
S Bhattacharyya, TJ Hope
Advances in Virology 2013
The current status of biomarkers for predicting toxicity
S Campion, J Aubrecht, K Boekelheide, DW Brewster, VS Vaidya, L Anderson, D Burt, E Dere, K Hwang, S Pacheco, J Saikumar, S Schomaker, M Sigman, F Goodsaid
Expert Opinion on Drug Metabolism & Toxicology 2013
Urine kidney injury molecule-1: a potential non-invasive biomarker for patients with renal cell carcinoma
PL Zhang, JW Mashni, VS Sabbisetti, CM Schworer, GD Wilson, SC Wolforth, KM Kernen, BD Seifman, MB Amin, TJ Geddes, F Lin, JV Bonventre, JM Hafron
International Urology and Nephrology 2013
Urine free light chains as a novel biomarker of acute kidney allograft injury
R Zhang, M Li, KK Chouhan, EE Simon, LL Hamm, V Batuman
Clinical Transplantation 2013
Tissue kidney injury molecule-1 expression in the prediction of renal function for several years after kidney biopsy
SS Ogrizovic, S Bojic, G Basta-Jovanovic, S Radojevic, J Pavlovic, JK Stevuljevic, V Dopsaj, R Naumovic
Disease Markers 2013
Role of the phosphatidylserine receptor TIM-1 in enveloped-virus entry
S Moller-Tank, AS Kondratowicz, RA Davey, PD Rennert, W Maury
Journal of virology 2013
EphrinB2 reverse signaling protects against capillary rarefaction and fibrosis after kidney injury
Y Kida, N Ieronimakis, C Schrimpf, M Reyes, JS Duffield
Journal of the American Society of Nephrology : JASN 2013
Performance of Kidney Injury Molecule-1 and Liver Fatty Acid-Binding Protein and Combined Biomarkers of AKI after Cardiac Surgery
CR Parikh, H Thiessen-Philbrook, AX Garg, D Kadiyala, MG Shlipak, JL Koyner, CL Edelstein, P Devarajan, UD Patel, M Zappitelli, CD Krawczeski, CS Passik, SG Coca
Clinical journal of the American Society of Nephrology : CJASN 2013
Chemokine Receptor Ccr1 Drives Neutrophil-Mediated Kidney Immunopathology and Mortality in Invasive Candidiasis
MS Lionakis, BG Fischer, JK Lim, M Swamydas, W Wan, CC Lee, JI Cohen, P Scheinberg, JL Gao, PM Murphy
PLoS pathogens 2012
Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice
S Xiao, CR Brooks, C Zhu, C Wu, JM Sweere, S Petecka, A Yeste, FJ Quintana, T Ichimura, RA Sobel, JV Bonventre, VK Kuchroo
Proceedings of the National Academy of Sciences 2012
Marking Renal Injury: Can We Move Beyond Serum Creatinine?
JL Slocum, M Heung, S Pennathur
Translational research : the journal of laboratory and clinical medicine 2012
Secreted Factors from Bone Marrow Stromal Cells Upregulate IL-10 and Reverse Acute Kidney Injury
JM Milwid, T Ichimura, M Li, Y Jiao, J Lee, JS Yarmush, B Parekkadan, AW Tilles, JV Bonventre, ML Yarmush
Stem Cells International 2012
Biomarkers for the prediction of acute kidney injury: a narrative review on current status and future challenges
HR de Geus, MG Betjes, J Bakker
Clinical Kidney Journal 2012
Interactions of human T cell immunoglobin mucins with apoptotic cells
Z Chen, J Qing, L Hu
Journal of Huazhong University of Science and Technology [Medical Sciences] 2012
The role of TIM-containing molecules in airway disease and their potential as therapeutic targets
I Vega-Carrascal, EP Reeves, NG McElvaney
Journal of inflammation research 2012
Rapamycin Ameliorates Kidney Fibrosis by Inhibiting the Activation of mTOR Signaling in Interstitial Macrophages and Myofibroblasts
G Chen, H Chen, C Wang, Y Peng, L Sun, H Liu, F Liu
PloS one 2012
TIM Family Proteins Promote the Lysosomal Degradation of the Nuclear Receptor NUR77
S Balasubramanian, SK Kota, VK Kuchroo, BD Humphreys, TB Strom
Science signaling 2012
Kidney Injury Molecule-1 Is Up-Regulated in Renal Epithelial Cells in Response to Oxalate In Vitro and in Renal Tissues in Response to Hyperoxaluria In Vivo
L Khandrika, S Koul, RB Meacham, HK Koul
PloS one 2012
Kim-1/Tim-1 and immune cells: shifting sands
T Ichimura, CR Brooks, JV Bonventre
Kidney international. Supplement 2012
MicroRNA 21 promotes fibrosis of the kidney by silencing metabolic pathways
BN Chau, C Xin, J Hartner, S Ren, AP Castano, G Linn, J Li, PT Tran, V Kaimal, X Huang, AN Chang, S Li, A Kalra, M Grafals, D Portilla, DA MacKenna, SH Orkin, JS Duffield
Science Translational Medicine 2012
Mechanisms of cadmium-induced proximal tubule injury: new insights with implications for biomonitoring and therapeutic interventions
WC Prozialeck, JR Edwards
The Journal of pharmacology and experimental therapeutics 2012
Draper acts through the JNK pathway to control synchronous engulfment of dying germline cells by follicular epithelial cells
JI Etchegaray, AK Timmons, AP Klein, TL Pritchett, E Welch, TL Meehan, C Li, K McCall
Development (Cambridge, England) 2012
Host cell factors in filovirus entry: novel players, new insights.
Hofmann-Winkler H, Kaup F, Pöhlmann S
Viruses 2012
The TIM1 gene regulates susceptibility to severe Hepatitis A virus infection in humans
Hye-Young kim, María Belén Eyheramonho, Muriel Pichavant, Carlos Gonzalez Cambaceres, Ponpan Matangkasomubut, Guillermo Cervio, Silvina Kuperman, Rita Moreiro, Krishnamurthy Konduru, Mohanraj Manangeeswaran, Gordon Freeman, Gerardo Kaplan, Rosemarie DeKruyff, Dale Umetsu, Sergio Rosenzweig
Journal of Clinical Investigation 2011
Cellular pathways involved in renal ischemia
Joseph V. Bonventre, Li Yang
Journal of Clinical Investigation 2011
Diannexin Protects against Renal Ischemia Reperfusion Injury and Targets Phosphatidylserines in Ischemic Tissue
KE Wever, FA Wagener, C Frielink, OC Boerman, GJ Scheffer, A Allison, R Masereeuw, GA Rongen
PloS one 2011
Dangers Within: DAMP Responses to Damage and Cell Death in Kidney Disease
DL Rosin, MD Okusa
Journal of the American Society of Nephrology : JASN 2011
The TIM-1:TIM-4 Pathway Enhances Renal Ischemia-Reperfusion Injury
S Rong, JK Park, T Kirsch, H Yagita, H Akiba, O Boenisch, H Haller, N Najafian, A Habicht
Journal of the American Society of Nephrology : JASN 2011
Cytoglobin, a Novel Member of the Globin Family, Protects Kidney Fibroblasts against Oxidative Stress under Ischemic Conditions
H Nishi, R Inagi, N Kawada, K Yoshizato, I Mimura, T Fujita, M Nangaku
The American Journal of Pathology 2011
Metchnikoff’s Policemen—Macrophages in Development, Homeostasis and Regeneration
JA Stefater, S Ren, RA Lang, JS Duffield
Trends in Molecular Medicine 2011
Repair of injured proximal tubule does not involve specialized progenitors
BD Humphreys, S Czerniak, DP DiRocco, W Hasnain, R Cheema, JV Bonventre
Proceedings of the National Academy of Sciences 2011
Pathophysiology of ischemic acute kidney injury
AA Sharfuddin, BA Molitoris
Nature Reviews Nephrology 2011
THE EMERGING ROLE OF THE TIM MOLECULES IN TRANSPLANTATION
MY Yeung, M McGrath, N Najafian
American Journal of Transplantation 2011
Angiotensin II Activation of mTOR Results in Tubulointerstitial Fibrosis through Loss of N-Cadherin
A Whaley-Connell, J Habibi, Z Panfili, MR Hayden, S Bagree, R Nistala, S Hyder, B Krueger, V Demarco, L Pulakat, CM Ferrario, A Parrish, JR Sowers
American Journal of Nephrology 2011
T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus
AS Kondratowicz, NJ Lennemann, PL Sinn, RA Davey, CL Hunt, S Moller-Tank, DK Meyerholz, P Rennert, RF Mullins, M Brindley, LM Sandersfeld, K Quinn, M Weller, PB McCray, J Chiorini, W Maury
Proceedings of the National Academy of Sciences 2011
Glomerular Expression of Kidney Injury Molecule-1 and Podocytopenia in Diabetic Glomerulopathy
X Zhao, Y Zhang, L Li, D Mann, JD Imig, N Emmett, G Gibbons, LM Jin
American Journal of Nephrology 2011
Biomarkers of Immunosuppressant Organ Toxicity after Transplantation - Status, Concepts and Misconceptions
U Christians, J Klawitter, J Klawitter, N Brunner, V Schmitz
Expert Opinion on Drug Metabolism & Toxicology 2011
Beginnings of a good apoptotic meal: the find-me and eat-me signaling pathways
KS Ravichandran
Immunity 2011
Biomarkers for drug-induced renal damage and nephrotoxicity-an overview for applied toxicology
TC Fuchs, P Hewitt
The AAPS Journal 2011
Fyn binds to and phosphorylates T cell immunoglobulin and mucin domain-1 (Tim-1)
ML Curtiss, BS Hostager, E Stepniak, M Singh, N Manhica, J Knisz, G Traver, PD Rennert, JD Colgan, PB Rothman
Molecular Immunology 2011
Molecular Imaging of the Kidneys
Z Szabo, N Alachkar, J Xia, WB Mathews, H Rabb
Seminars in Nuclear Medicine 2011
Antagonism of TIM-1 blocks the development of disease in a humanized mouse model of allergic asthma
Sanchaita Sonar, Yen-Ming Hsu, Melanie Conrad, Gerard Majeau, Ayse Kilic, Ellen Garber, Yan Gao, Chioma Nwankwo, Gundi Willer, Jan Dudda, Hellen Kim, Veronique Bailly, Axel Pagenstecher, Paul Rennert, Harald Renz
Journal of Clinical Investigation 2010
TIM1 is an endogenous ligand for LMIR5/CD300b: LMIR5 deficiency ameliorates mouse kidney ischemia/reperfusion injury
Y Yamanishi, J Kitaura, K Izawa, A Kaitani, Y Komeno, M Nakamura, S Yamazaki, Y Enomoto, T Oki, H Akiba, T Abe, T Komori, Y Morikawa, H Kiyonari, T Takai, K Okumura, T Kitamura
Journal of Experimental Medicine 2010
T cell/transmembrane, Ig, and mucin-3 allelic variants differentially recognize phosphatidylserine and mediate phagocytosis of apoptotic cells
RH DeKruyff, X Bu, A Ballesteros, C Santiago, YL Chim, HH Lee, P Karisola, M Pichavant, GG Kaplan, DT Umetsu, GJ Freeman, JM Casasnovas
Journal of immunology (Baltimore, Md. : 1950) 2010
TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity: TIM genes: a family of PtdSer receptors
GJ Freeman, JM Casasnovas, DT Umetsu, RH DeKruyff
Immunological Reviews 2010
TIM2 Gene Deletion Results in Susceptibility to Cisplatin-Induced Kidney Toxicity
A Krishnamoorthy, ME Clement, E O'Leary, JV Bonventre, VS Vaidya
Toxicological Sciences 2010
Macrophage Wnt7b is critical for kidney repair and regeneration
SL Lin, B Li, S Rao, EJ Yeo, TE Hudson, BT Nowlin, H Pei, L Chen, JJ Zheng, TJ Carroll, JW Pollard, AP McMahon, RA Lang, JS Duffield
Proceedings of the National Academy of Sciences 2010
The melanoma-associated transmembrane glycoprotein Gpnmb controls trafficking of cellular debris for degradation and is essential for tissue repair
B Li, AP Castano, TE Hudson, BT Nowlin, SL Lin, JV Bonventre, KD Swanson, JS Duffield
The FASEB Journal 2010
Searching for novel intercellular signal-transducing molecules in the kidney and their clinical application
K Mori, M Mukoyama, K Nakao
Clinical and Experimental Nephrology 2010
Acute kidney injury in childhood: should we be worried about progression to CKD?
SL Goldstein, P Devarajan
Pediatric Nephrology 2010
The Use of Targeted Biomarkers for Chronic Kidney Disease
P Devarajan
Advances in Chronic Kidney Disease 2010
TIM-4, a Receptor for Phosphatidylserine, Controls Adaptive Immunity by Regulating the Removal of Antigen-Specific T Cells
LA Albacker, P Karisola, YJ Chang, SE Umetsu, M Zhou, O Akbari, N Kobayashi, N Baumgarth, GJ Freeman, DT Umetsu, RH DeKruyff
Journal of immunology (Baltimore, Md. : 1950) 2010
Emergence of biomarkers in nephropharmacology
E Khan, V Batuman, JJ Lertora
Biomarkers in Medicine 2010
Find-me and eat-me signals in apoptotic cell clearance: progress and conundrums
KS Ravichandran
Journal of Experimental Medicine 2010
Phosphatidylserine receptor Tim-4 is essential for the maintenance of the homeostatic state of resident peritoneal macrophages
K Wong, PA Valdez, C Tan, S Yeh, JA Hongo, W Ouyang
Proceedings of the National Academy of Sciences 2010
Tim-1 is induced on germinal centre B cells through B-cell receptor signalling but is not essential for the germinal centre response
SH Wong, JL Barlow, S Nabarro, PG Fallon, AN McKenzie
Immunology 2010
Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury
L Yang, TY Besschetnova, CR Brooks, JV Shah, JV Bonventre
Nature Medicine 2010
Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis
BD Humphreys, SL Lin, A Kobayashi, TE Hudson, BT Nowlin, JV Bonventre, MT Valerius, AP McMahon, JS Duffield
The American Journal of Pathology 2009
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009
Mediators of Inflammation in Acute Kidney Injury
A Akcay, Q Nguyen, CL Edelstein
Mediators of Inflammation 2009
Dysfunctional cystic fibrosis transmembrane conductance regulator inhibits phagocytosis of apoptotic cells with proinflammatory consequences
RW Vandivier, TR Richens, SA Horstmann, AM deCathelineau, M Ghosh, SD Reynolds, YQ Xiao, DW Riches, J Plumb, E Vachon, GP Downey, PM Henson
American journal of physiology. Lung cellular and molecular physiology 2009
Serum Amyloid P Inhibits Fibrosis Through Fc R-Dependent Monocyte-Macrophage Regulation in Vivo
AP Castaño, SL Lin, T Surowy, BT Nowlin, SA Turlapati, T Patel, A Singh, S Li, ML Lupher, JS Duffield
Science Translational Medicine 2009
The costimulatory role of TIM molecules
R Rodriguez-Manzanet, R DeKruyff, VK Kuchroo, DT Umetsu
Immunological Reviews 2009
Sequence, structure, function, immunity: structural genomics of costimulation
K Chattopadhyay, E Lazar-Molnar, Q Yan, R Rubinstein, C Zhan, V Vigdorovich, UA Ramagopal, J Bonanno, SG Nathenson, SC Almo
Immunological Reviews 2009
Comparative Analysis of Novel Noninvasive Renal Biomarkers and Metabonomic Changes in a Rat Model of Gentamicin Nephrotoxicity
M Sieber, D Hoffmann, M Adler, VS Vaidya, M Clement, JV Bonventre, N Zidek, E Rached, A Amberg, JJ Callanan, W Dekant, A Mally
Toxicological Sciences 2009
Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR
K Al-Nedawi, B Meehan, RS Kerbel, AC Allison, J Rak
Proceedings of the National Academy of Sciences 2009
Structural changes in the epithelium of the small intestine and immune cell infiltration of enteric ganglia following acute mucosal damage and local inflammation
L Pontell, P Castelucci, M Bagyánszki, T Jovic, M Thacker, K Nurgali, R Bron, JB Furness
Virchows Archiv 2009
Preclinical evaluation of novel urinary biomarkers of cadmium nephrotoxicity
WC Prozialeck, JR Edwards, VS Vaidya, JV Bonventre
Toxicology and Applied Pharmacology 2009
Expression of kidney injury molecule-1 (Kim-1) in relation to necrosis and apoptosis during the early stages of Cd-induced proximal tubule injury
WC Prozialeck, JR Edwards, PC Lamar, J Liu, VS Vaidya, JV Bonventre
Toxicology and Applied Pharmacology 2009
Reduction of proteinuria in adriamycin-induced nephropathy is associated with reduction of renal kidney injury molecule (Kim-1) over time
AB Kramer, MM van Timmeren, TA Schuurs, VS Vaidya, JV Bonventre, H Goor, G Navis
American journal of physiology. Renal physiology 2009
The ins and outs of phospholipid asymmetry in the plasma membrane: roles in health and disease
B Fadeel, D Xue
Critical Reviews in Biochemistry and Molecular Biology 2009
Tubular Expression of KIM-1 Does not Predict Delayed Function After Transplantation
B Schroppel, B Kruger, L Walsh, M Yeung, S Harris, K Garrison, J Himmelfarb, SM Lerner, JS Bromberg, PL Zhang, JV Bonventre, Z Wang, AB Farris, RB Colvin, BT Murphy, JP Vella
Journal of the American Society of Nephrology : JASN 2009
Pericytes and Perivascular Fibroblasts Are the Primary Source of Collagen-Producing Cells in Obstructive Fibrosis of the Kidney
SL Lin, T Kisseleva, DA Brenner, JS Duffield
The American Journal of Pathology 2008
TIM-1 and TIM-3 proteins in immune regulation
EW Su, JY Lin, LP Kane
Cytokine 2008
Emerging concepts in acute kidney injury following cardiac surgery
C Hudson, J Hudson, M Swaminathan, A Shaw, M Stafford-Smith, UD Patel
Seminars in cardiothoracic and vascular anesthesia 2008

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