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Augmentation of lung liquid clearance via adenovirus-mediated transfer of a Na,K-ATPase beta1 subunit gene.

P Factor, … , R Perrin, J I Sznajder

P Factor, … , R Perrin, J I Sznajder

Published October 1, 1998
Citation Information: J Clin Invest. 1998;102(7):1421-1430. https://doi.org/10.1172/JCI3214.

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FXYD3 facilitates Na⁺ and liquid absorption across human airway epithelia by increasing the transport capacity of the Na/K ATPase. Cano Portillo C, Villacreses R, Thurman AL, Pezzulo AA, Zabner J, Thornell IM	American journal of physiology. Cell physiology	2022
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Modulation of α-ENaC and α 1 -Na + -K + -ATPase by cAMP and dexamethasone in alveolar epithelial cells A Dagenais, C Denis, MF Vives, S Girouard, C Massé, T Nguyen, T Yamagata, C Grygorczyk, R Kothary, Y Berthiaume	American journal of physiology. Lung cellular and molecular physiology	2001
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Direct correlation between positron emission tomographic images of two reporter genes delivered by two distinct adenoviral vectors. Yaghoubi SS, Wu L, Liang Q, Toyokuni T, Barrio JR, Namavari M, Satyamurthy N, Phelps ME, Herschman HR, Gambhir SS	Gene therapy	2001
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Lung fluid transport in aquaporin-5 knockout mice T Ma, N Fukuda, Y Song, MA Matthay, AS Verkman	Journal of Clinical Investigation	2000
G protein-coupled receptors regulate Na+,K+-ATPase activity and endocytosis by modulating the recruitment of adaptor protein 2 and clathrin G Ogimoto, GA Yudowski, CJ Barker, M Köhler, AI Katz, E Féraille, CH Pedemonte, PO Berggren, AM Bertorello	Proceedings of the National Academy of Sciences	2000
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Adenovirus-mediated transfer of an Na+/K+-ATPase beta1 subunit gene improves alveolar fluid clearance and survival in hyperoxic rats P Factor, V Dumasius, F Saldias, LA Brown, JI Sznajder	Human Gene Therapy	2000
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Gene transfer to adult human lung tissue ex vivo S McBride, D Rannie, DJ Harrison	Gene Therapy	2000
Pretreatment with cationic lipid-mediated transfer of the Na+K+-ATPase pump in a mouse model in vivo augments resolution of high permeability pulmonary oedema M Stern, K Ulrich, C Robinson, J Copeland, U Griesenbach, C Masse, S Cheng, F Munkonge, D Geddes, Y Berthiaume, E Alton	Gene Therapy	2000
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Alveolar epithelial fluid transport can be simultaneously upregulated by both KGF and β-agonist therapy Y Wang, HG Folkesson, C Jayr, LB Ware, MA Matthay	Journal of applied physiology	1999

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