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Thomas A. Wynn
Published March 1, 2007
Citation Information: J Clin Invest. 2007;117(3):524-529. https://doi.org/10.1172/JCI31487.
Citation Information: J Clin Invest. 2007;117(3):524-529. https://doi.org/10.1172/JCI31487.
Abstract
Fibroproliferative diseases, including the pulmonary fibroses, systemic sclerosis, liver cirrhosis, cardiovascular disease, progressive kidney disease, and macular degeneration, are a leading cause of morbidity and mortality and can affect all tissues and organ systems. Fibrotic tissue remodeling can also influence cancer metastasis and accelerate chronic graft rejection in transplant recipients. Nevertheless, despite its enormous impact on human health, there are currently no approved treatments that directly target the mechanism(s) of fibrosis. The primary goals of this Review series on fibrotic diseases are to discuss some of the major fibroproliferative diseases and to identify the common and unique mechanisms of fibrogenesis that might be exploited in the development of effective antifibrotic therapies.
Authors
Thomas A. Wynn
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Telocytes in Fibrosis Diseases: From Current Findings to Future Clinical Perspectives
Wei XJ, Chen TQ, Yang XJ |
Cell transplantation | 2022 |
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Collagen and Microvascularization in Placentas From Young and Older Mares
Neto da Silva AC, Costa AL, Teixeira A, Alpoim-Moreira J, Fernandes C, Fradinho MJ, Rebordão MR, Silva E, Ferreira da Silva J, Bliebernicht M, Alexandre-Pires G, Ferreira-Dias G |
Frontiers in Veterinary Science | 2022 |
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An Inflammatory Response-Related Gene Signature Reveals Distinct Survival Outcome and Tumor Microenvironment Characterization in Pancreatic Cancer
Xie F, Huang X, He C, Wang R, Li S |
Frontiers in Molecular Biosciences | 2022 |
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Antifibrotic Mechanism of Piceatannol in Bleomycin-Induced Pulmonary Fibrosis in Mice
Sheng H, Lin G, Zhao S, Li W, Zhang Z, Zhang W, Yun L, Yan X, Hu H |
Frontiers in pharmacology | 2022 |
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Emerging role of tumor suppressor p53 in acute and chronic kidney diseases.
Overstreet JM, Gifford CC, Tang J, Higgins PJ, Samarakoon R |
Cellular and molecular life sciences : CMLS | 2022 |
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Ogerin mediated inhibition of TGF-β(1) induced myofibroblast differentiation is potentiated by acidic pH
Bell TJ, Nagel DJ, Woeller CF, Kottmann RM |
PloS one | 2022 |
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Proposed Cellular Function of the Human FAM111B Protein and Dysregulation in Fibrosis and Cancer
Arowolo A, Malebana M, Sunda F, Rhoda C |
Frontiers in Oncology | 2022 |
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Myofibroblasts as important diagnostic and prognostic indicators of oral squamous cell carcinoma: An immunohistochemical study using alpha-smooth muscle actin antibody
Gandhi P, Kaur M, Punia RS, Halappa TS, Singh HP |
Journal of Oral and Maxillofacial Pathology : JOMFP | 2022 |
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Inhibitory Effects of 3′,4′-Dihydroxyflavonol in a Mouse Model of Glaucoma Filtration Surgery and TGFβ1-Induced Responses in Human Tenon's Fibroblasts
Fan Gaskin JC, Kong RC, Shah MH, Edgley AJ, Peshavariya HM, Chan EC |
Translational Vision Science & Technology | 2022 |
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Extra Cellular Matrix Remodeling: An Adjunctive Target for Spinal Cord Injury and Intervertebral Disc Degeneration
Kumar A, Kumar N, Pathak Z, Kumar H |
2022 | |
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Bariatric surgery for diabetic comorbidities: A focus on hepatic, cardiac and renal fibrosis
Ding H, Zhang Y, Ma X, Zhang Z, Xu Q, Liu C, Li B, Dong S, Li L, Zhu J, Zhong M, Zhang G |
Frontiers in pharmacology | 2022 |
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Cathelicidin Treatment Silences Epithelial–Mesenchymal Transition Involved in Pulmonary Fibrosis in a Murine Model of Hypersensitivity Pneumonitis
Lemieszek MK, Golec M, Zwoliński J, Dutkiewicz J, Milanowski J |
International journal of molecular sciences | 2022 |
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Ameliorating Fibrosis in Murine and Human Tissues with END55, an Endostatin-Derived Fusion Protein Made in Plants.
Mlakar L, Garrett SM, Watanabe T, Sanderson M, Nishimoto T, Heywood J, Helke KL, Pilewski JM, Herzog EL, Feghali-Bostwick C |
Biomedicines | 2022 |
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Connexin43 in Post-Surgical Peritoneal Adhesion Formation.
Chua JW, Thangaveloo M, Lim DXE, Madden LE, Phillips ARJ, Becker DL |
2022 | |
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Renal Fibrosis in Lupus Nephritis
Sciascia S, Cozzi M, Barinotti A, Radin M, Cecchi I, Fenoglio R, Mancardi D, Wilson Jones G, Rossi D, Roccatello D |
International journal of molecular sciences | 2022 |
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MiR-302d inhibits TGFB-induced EMT and promotes MET in primary human RPE cells
Hu X, Binter M, Hufendiek K, Tode J, Framme C, Fuchs H |
PloS one | 2022 |
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Pulmonary Fibrosis as a Result of Acute Lung Inflammation: Molecular Mechanisms, Relevant In Vivo Models, Prognostic and Therapeutic Approaches
Savin IA, Zenkova MA, Sen\u2019kova AV |
International journal of molecular sciences | 2022 |
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Phenotypic screening of 1,953 FDA-approved drugs reveals 26 hits with potential for repurposing for Peyronie’s disease
Ilg MM, Lapthorn AR, Ralph DJ, Cellek S |
PloS one | 2022 |
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Calreticulin in renal fibrosis: A short review
Politis PK, Charonis AS |
Journal of Cellular and Molecular Medicine | 2022 |
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Trickle infection with Heligmosomoides polygyrus results in decreased worm burdens but increased intestinal inflammation and scarring
Ariyaratne A, Kim SY, Pollo SM, Perera S, Liu H, Nguyen WN, Leon Coria A, de Cassia Luzzi M, Bowron J, Szabo EK, Patel KD, Wasmuth JD, Nair MG, Finney CA |
Frontiers in immunology | 2022 |
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Immune cell populations differ in patients undergoing revision total knee arthroplasty for arthrofibrosis
Limberg AK, Salib CG, Tibbo ME, Vargas-Hernandez JS, Bettencourt JW, Bayram B, Berry CE, Dudakovic A, Bolon B, van Wijnen AJ, Morrey ME, Sanchez-Sotelo J, Berry DJ, Carter JM, Abdel MP |
Scientific Reports | 2022 |
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Role of platelet factor 4 in arteriovenous fistula maturation failure: What do we know so far?
Xiao Y, Vazquez-Padron RI, Martinez L, Singer HA, Woltmann D, Salman LH |
The Journal of Vascular Access | 2022 |
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A novel and low-toxic peptide DR3penA alleviates pulmonary fibrosis by regulating the MAPK/miR-23b-5p/AQP5 signaling axis.
Wang D, Deng B, Cheng L, Li J, Zhang J, Zhang X, Guo X, Yan T, Yue X, An Y, Zhang B, Yang W, Xie J, Wang R |
Acta pharmaceutica Sinica. B | 2022 |
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Quantification of inflammatory, angiogenic, and fibrous components of reactive oral lesions with an insight into the pathogenesis
Vasanthi V, Divya B, Ramadoss R, Deena P, Annasamy RK, Rajkumar K |
Journal of Oral and Maxillofacial Pathology : JOMFP | 2022 |
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Vitreous humor proteome: unraveling the molecular mechanisms underlying proliferative and neovascular vitreoretinal diseases
dos Santos FM, Ciordia S, Mesquita J, de Sousa JP, Paradela A, Tomaz CT, Passarinha LA |
2022 | |
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Pilot Study of Anti-Th2 Immunotherapy for the Treatment of Breast Cancer-Related Upper Extremity Lymphedema
BJ Mehrara, HJ Park, RP Kataru, J Bromberg, M Coriddi, JE Baik, J Shin, C Li, MR Cavalli, EM Encarnacion, M Lee, KJ Zee, E Riedel, JH Dayan |
Biology : open access journal | 2021 |
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Cellular Senescence in Lung Fibrosis
F Hernandez-Gonzalez, R Faner, M Rojas, A Agustí, M Serrano, J Sellarés |
International journal of molecular sciences | 2021 |
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The Dynamic Inflammatory Tissue Microenvironment: Signality and Disease Therapy by Biomaterials
R Mata, Y Yao, W Cao, J Ding, T Zhou, Z Zhai, C Gao |
Research | 2021 |
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Current Pharmacological Strategies for Duchenne Muscular Dystrophy
S Yao, Z Chen, Y Yu, N Zhang, H Jiang, G Zhang, Z Zhang, B Zhang |
Frontiers in Cell and Developmental Biology | 2021 |
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Myofibroblasts: Methods and Protocols
B Hinz, D Lagares |
2021 | |
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NLRC5 Deficiency Deregulates Hepatic Inflammatory Response but Does Not Aggravate Carbon Tetrachloride-Induced Liver Fibrosis
AJ Quenum, A Shukla, F Rexhepi, M Cloutier, A Ghosh, TA Kufer, S Ramanathan, S Ilangumaran |
Frontiers in immunology | 2021 |
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Centella asiatica Extract Attenuates Kidney Fibrosis Through Reducing Mesenchymal Transition and Inflammation in Ureteral Ligation Model in Mice
DC Sari, S Budiharjo, H Afifah, D Jasmin, O Kokasih, TG Putri, K Arifiani, WA Setyaningsih, N Arfian |
Frontiers in pharmacology | 2021 |
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Fighting the storm: could novel anti-TNFα and anti-IL-6 C. sativa cultivars tame cytokine storm in COVID-19?
A Kovalchuk, B Wang, D Li, R Rodriguez-Juarez, S Ilnytskyy, I Kovalchuk, O Kovalchuk |
Aging | 2021 |
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Subretinal fibrosis in neovascular age-related macular degeneration: current concepts, therapeutic avenues, and future perspectives
L Tenbrock, J Wolf, S Boneva, A Schlecht, H Agostini, P Wieghofer, G Schlunck, C Lange |
Cell and Tissue Research | 2021 |
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Ursodesoxycholic acid alleviates liver fibrosis via proregeneration by activation of the ID1‐WNT2/HGF signaling pathway
, Y Luo, S Lu, H Ma, W Zhang, Y Zhu, G Sun, X Sun |
Clinical and Translational Medicine | 2021 |
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Myeloid cell diversification during regenerative inflammation: Lessons from skeletal muscle
A Patsalos, P Tzerpos, X Wei, L Nagy |
Seminars in Cell & Developmental Biology | 2021 |
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Myeloid interleukin-4 receptor α is essential in postmyocardial infarction healing by regulating inflammation and fibrotic remodeling
J Song, RA Frieler, SE Whitesall, Y Chung, TM Vigil, LA Muir, J Ma, F Brombacher, SN Goonewardena, CN Lumeng, DR Goldstein, RM Mortensen |
American journal of physiology. Heart and circulatory physiology | 2021 |
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Early Aberrant Angiogenesis Due to Elastic Fiber Fragmentation in Aortic Valve Disease
RB Hinton, AL Juraszek, AM Opoka, BJ Landis, JM Smith, RP Mecham, KE Bove |
Journal of Cardiovascular Development and Disease | 2021 |
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Anti-fibrotic treatments for chronic liver diseases: The present and the future
N Odagiri, T Matsubara, M Sato-Matsubara, H Fujii, M Enomoto, N Kawada |
Clinical and Molecular Hepatology | 2021 |
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Mechanical stretch promotes hypertrophic scar formation through mechanically activated cation channel Piezo1
J He, B Fang, S Shan, Y Xie, C Wang, Y Zhang, X Zhang, Q Li |
Cell Death and Disease | 2021 |
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The Potential Use of Cannabis in Tissue Fibrosis
N Pryimak, M Zaiachuk, O Kovalchuk, I Kovalchuk |
Frontiers in Cell and Developmental Biology | 2021 |
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Interactions between Cancer-Associated Fibroblasts and T Cells in the Pancreatic Tumor Microenvironment and the Role of Chemokines
L Gorchs, H Kaipe |
Cancers | 2021 |
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Extracellular Vesicles in Organ Fibrosis: Mechanisms, Therapies, and Diagnostics
DR Brigstock |
Cells | 2021 |
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AMD-Like Substrate Causes Epithelial Mesenchymal Transition in iPSC-Derived Retinal Pigment Epithelial Cells Wild Type but Not C3-Knockout
B Chinchilla, R Fernandez-Godino |
International journal of molecular sciences | 2021 |
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The perplexing role of RAGE in pulmonary fibrosis: causality or casualty?
TN Perkins, TD Oury |
Therapeutic advances in respiratory disease | 2021 |
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Helminth Coinfection Is Associated With Enhanced Plasma Levels of Matrix Metalloproteinases and Tissue Inhibitor of Metalloproteinases in Tuberculous Lymphadenitis
GR Kathamuthu, K Moideen, K Thiruvengadam, R Sridhar, D Baskaran, S Babu |
Frontiers in Cellular and Infection Microbiology | 2021 |
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Highlighting the Relevance of CD8+ T Cells in Filarial Infections
A Kwarteng, E Asiedu, KK Koranteng, SO Asiedu |
Frontiers in immunology | 2021 |
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Modulating Cellular Responses to Mechanical Forces to Promote Wound Regeneration
S Mascharak, HE desJardins-Park, MF Davitt, NJ Guardino, GC Gurtner, DC Wan, MT Longaker |
Advances in Skin & Wound Care | 2021 |
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PPARγ and TGFβ—Major Regulators of Metabolism, Inflammation, and Fibrosis in the Lungs and Kidneys
G Kökény, L Calvier, G Hansmann |
International journal of molecular sciences | 2021 |
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Biglycan expression and its function in human ligamentum flavum
H Salimi, A Suzuki, H Habibi, K Orita, Y Hori, A Yabu, H Terai, K Tamai, H Nakamura |
Scientific Reports | 2021 |
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The Serum from Patients with Secondary Frozen Shoulder Following Rotator Cuff Repair Induces Shoulder Capsule Fibrosis and Promotes Macrophage Polarization and Fibroblast Activation
Y Sun, J Lin, Z Luo, Y Zhang, J Chen |
Journal of inflammation research | 2021 |
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In vivo therapeutic success of MicroRNA-155 antagomir in a mouse model of pulmonary fibrosis induced by bleomycin
X Sun, Y Kang, S Xue, J Zou, J Xu, D Tang, H Qin |
The Korean Journal of Internal Medicine | 2021 |
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MicroRNAs in Transforming Growth Factor-Beta Signaling Pathway Associated With Fibrosis Involving Different Systems of the Human Body
X Xu, P Hong, Z Wang, Z Tang, K Li |
Frontiers in Molecular Biosciences | 2021 |
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Toward the Effective Bioengineering of a Pathological Tissue for Cardiovascular Disease Modeling: Old Strategies and New Frontiers for Prevention, Diagnosis, and Therapy
L Iop |
Frontiers in Cardiovascular Medicine | 2021 |
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Cytoskeleton Reorganization in EndMT—The Role in Cancer and Fibrotic Diseases
WM Ciszewski, ME Wawro, I Sacewicz-Hofman, K Sobierajska |
International journal of molecular sciences | 2021 |
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Fibrotic expression profile analysis reveals repurposed drugs with potential anti-fibrotic mode of action
E Karatzas, AC Kakouri, G Kolios, A Delis, GM Spyrou, C Chan |
PloS one | 2021 |
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tRNA-Derived Fragment tRF-17-79MP9PP Attenuates Cell Invasion and Migration via THBS1/TGF-β1/Smad3 Axis in Breast Cancer
D Mo, F He, J Zheng, H Chen, L Tang, F Yan |
Frontiers in Oncology | 2021 |
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Neglected No More: Emerging Cellular Therapies in Traumatic Injury
LE Lowry, MC Herzig, BA Christy, R Schäfer, S Pati, AP Cap, JA Bynum |
Stem Cell Reviews and Reports | 2021 |
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Discovery of a Lead Compound for Specific Inhibition of Type I Collagen Production in Fibrosis
B Stefanovic, HA Michaels, A Nefzi |
ACS Medicinal Chemistry Letters | 2021 |
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Enhancing Peptide Biomaterials for Biofabrication
K Firipis, DR Nisbet, SJ Franks, RM Kapsa, E Pirogova, RJ Williams, A Quigley |
Polymers | 2021 |
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Endostatin in fibrosis and as a potential candidate of anti-fibrotic therapy
Z Zhang, , Z Shen, J Quan, C Lin, X Li, G Hu |
Drug Delivery | 2021 |
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Reparation of an Inflamed Air-Liquid Interface Cultured A549 Cells with Nebulized Nanocurcumin
MJ Altube, LI Caimi, C Huck-Iriart, MJ Morilla, EL Romero |
Pharmaceutics | 2021 |
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Tacrolimus action pathways in an ointment base for hypertrophic scar prevention in a rabbit ear model
MC Menezes, M Buzelin, CB Nunes, LR Alberti |
Anais Brasileiros de Dermatologia | 2021 |
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Stromal Cells Underlining the Paths From Autoimmunity, Inflammation to Cancer With Roles Beyond Structural and Nutritional Support
AM Honan, Z Chen |
Frontiers in Cell and Developmental Biology | 2021 |
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Epithelial-Mesenchymal Transition and Senescence in the Retinal Pigment Epithelium of NFE2L2/PGC-1α Double Knock-Out Mice
J Blasiak, A Koskela, E Pawlowska, M Liukkonen, J Ruuth, E Toropainen, JM Hyttinen, J Viiri, JE Eriksson, H Xu, M Chen, S Felszeghy, K Kaarniranta |
International journal of molecular sciences | 2021 |
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A Review on Preparation of Betulinic Acid and Its Biological Activities
H Lou, H Li, S Zhang, H Lu, Q Chen |
Molecules (Basel, Switzerland) | 2021 |
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Effect of vitamin D supplementation in patients with chronic hepatitis C after direct-acting antiviral treatment: a randomized, double-blind, placebo-controlled trial
S Sriphoosanaphan, K Thanapirom, SJ Kerr, S Suksawatamnuay, P Thaimai, S Sittisomwong, K Sonsiri, N Srisoonthorn, N Teeratorn, N Tanpowpong, B Chaopathomkul, S Treeprasertsuk, Y Poovorawan, P Komolmit |
PeerJ | 2021 |
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Bidirectional epithelial–mesenchymal crosstalk provides self-sustaining profibrotic signals in pulmonary fibrosis
L Yao, Y Zhou, J Li, L Wickens, F Conforti, A Rattu, FM Ibrahim, A Alzetani, BG Marshall, SV Fletcher, D Hancock, T Wallis, J Downward, RM Ewing, L Richeldi, P Skipp, DE Davies, MG Jones, Y Wang |
The Journal of biological chemistry | 2021 |
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Human Primary Dermal Fibroblasts Interacting with 3-Dimensional Matrices for Surgical Application Show Specific Growth and Gene Expression Programs
S Grossi, A Grimaldi, T Congiu, A Parnigoni, G Campanelli, P Campomenosi |
International journal of molecular sciences | 2021 |
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Pharmacological Activities and Mechanisms of Hirudin and Its Derivatives - A Review
C Junren, X Xiaofang, Z Huiqiong, L Gangmin, Y Yanpeng, C Xiaoyu, G Yuqing, L Yanan, Z Yue, P Fu, P Cheng |
Frontiers in pharmacology | 2021 |
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Inhibition of epithelial–mesenchymal transition in retinal pigment epithelial cells by a retinoic acid receptor-α agonist
Y Kobayashi, K Tokuda, C Yamashiro, F Higashijima, T Yoshimoto, M Ota, T Ogata, A Ashimori, M Hatano, M Kobayashi, SH Uchi, M Wakuta, K Kimura |
Scientific Reports | 2021 |
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Inhibition of PDE4 by apremilast attenuates skin fibrosis through directly suppressing activation of M1 and T cells
Q Lu, C Fan, C Xiang, B Wu, H Lu, C Feng, X Yang, H Li, W Tang |
Acta Pharmacologica Sinica | 2021 |
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Artemisinin and artemisinin derivatives as anti-fibrotic therapeutics
D Dolivo, P Weathers, T Dominko |
Acta pharmaceutica Sinica. B | 2021 |
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Presence of Uterine Leiomyomas Has No Significant Impact on Gene Expression Profile in the Scalp of Patients with Central Centrifugal Cicatricial Alopecia.
Jamerson TA, Talbot CC Jr, Dina Y, Aguh C |
2021 | |
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Effect of long non-coding RNA AK021443 on promoting hepatic fibrosis in vitro
Yang Y, Min Z |
Molecular medicine reports | 2021 |
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The interaction of S100A16 and GRP78 actives endoplasmic reticulum stress-mediated through the IRE1α/XBP1 pathway in renal tubulointerstitial fibrosis
Jin R, Zhao A, Han S, Zhang D, Sun H, Li M, Su D, Liang X |
Cell Death and Disease | 2021 |
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LRG1 promotes epithelial-mesenchymal transition of retinal pigment epithelium cells by activating NOX4.
Zhou L, Shi DP, Chu WJ, Yang LL, Xu HF |
International Journal of Ophthalmology | 2021 |
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The 'Yin and Yang' of Cancer Cell Growth and Mechanosensing.
Amer M, Shi L, Wolfenson H |
Cancers | 2021 |
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Outcomes of Idiopathic Pulmonary Fibrosis Improve with Obesity: A Rural Appalachian Experience
Sangani RG, Ghio AJ, Mujahid H, Patel Z, Catherman K, Wen S, Parker JE |
Southern Medical Journal | 2021 |
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GARP is a key molecule for mesenchymal stromal cell responses to TGF‐β and fundamental to control mitochondrial ROS levels
AB CarrilloGálvez, S GálvezPeisl, JE GonzálezCorrea, M HaroCarrillo, V Ayllón, P CarmonaSáez, V RamosMejía, P GalindoMoreno, FE Cara, S GranadosPrincipal, P Muñoz, F Martin, P Anderson |
Stem Cells Translational Medicine | 2020 |
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Innate Immunity Effector Cells as Inflammatory Drivers of Cardiac Fibrosis
D Baci, A Bosi, L Parisi, G Buono, L Mortara, G Ambrosio, A Bruno |
International journal of molecular sciences | 2020 |
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The protective effects of granulocyte-macrophage colony-stimulating factor against radiation-induced lung injury
D Hu, Y Zhang, R Cao, Y Hao, X Yang, T Tian, J Zhang |
Translational Lung Cancer Research | 2020 |
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Human cardiac fibroblasts expressing VCAM1 improve heart function in postinfarct heart failure rat models by stimulating lymphangiogenesis
T Iwamiya, BD Segard, Y Matsuoka, T Imamura, V Lionetti |
PloS one | 2020 |
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Targeting the renin-angiotensin-aldosterone system in fibrosis
M AlQudah, TM Hale, MP Czubryt |
Matrix biology : journal of the International Society for Matrix Biology | 2020 |
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Potential therapeutic manipulations of the CXCR3 chemokine axis for the treatment of inflammatory fibrosing diseases
MK Groover, JM Richmond |
F1000Research | 2020 |
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Revisiting Cell Death Responses in Fibrotic Lung Disease: Crosstalk between Structured and Non-Structured Cells
K Fukushima, T Satoh, H Kida, A Kumanogoh |
Diagnostics | 2020 |
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Genomics of Human Fibrotic Diseases: Disordered Wound Healing Response
RC Stone, V Chen, J Burgess, S Pannu, M Tomic-Canic |
International journal of molecular sciences | 2020 |
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The Endothelium as a Driver of Liver Fibrosis and Regeneration
E Lafoz, M Ruart, A Anton, A Oncins, V Hernández-Gea |
Cells | 2020 |
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Attenuation of Dupuytren’s fibrosis via targeting of the STAT1 modulated IL-13Rα1 response
M Akbar, E Garcia-Melchor, S Chilaka, KJ Little, S Sood, JH Reilly, FY Liew, IB McInnes, NL Millar |
Science Advances | 2020 |
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T Cells in Fibrosis and Fibrotic Diseases
M Zhang, S Zhang |
Frontiers in immunology | 2020 |
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Protein tyrosine phosphatase-α amplifies transforming growth factor-β-dependent profibrotic signaling in lung fibroblasts
Y Aschner, M Nelson, M Brenner, H Roybal, K Beke, C Meador, D Foster, KA Correll, PR Reynolds, K Anderson, EF Redente, J Matsuda, DW Riches, SD Groshong, A Pozzi, J Sap, Q Wang, D Rajshankar, CA McCulloch, RL Zemans, GP Downey |
American journal of physiology. Lung cellular and molecular physiology | 2020 |
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Progress in drug delivery system for fibrosis therapy
L Xing, X Chang, L Shen, C Zhang, Y Fan, C Cho, Z Zhang, H Jiang |
Asian Journal of Pharmaceutical Sciences | 2020 |
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Ablation of Gadd45β ameliorates the inflammation and renal fibrosis caused by unilateral ureteral obstruction
SJ Moon, JH Kim, YK Choi, CH Lee, JH Hwang |
Journal of Cellular and Molecular Medicine | 2020 |
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Advanced co-culture 3D breast cancer model for investigation of fibrosis induced by external stimuli: optimization study
I Yakavets, A Francois, A Benoit, JL Merlin, L Bezdetnaya, G Vogin |
Scientific Reports | 2020 |
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Angiotensin-converting-enzyme inhibitor prevents skeletal muscle fibrosis in myocardial infarction mice
N Kakutani, S Takada, H Nambu, J Matsumoto, T Furihata, T Yokota, A Fukushima, S Kinugawa |
Skeletal Muscle | 2020 |
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Myofibroblast activation in synthetic fibrous matrices composed of dextran vinyl sulfone
CD Davidson, DK Jayco, DL Matera, SJ DePalma, HL Hiraki, WY Wang, BM Baker |
Acta Biomaterialia | 2020 |
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Emerging Roles of Matricellular Proteins in Systemic Sclerosis
D Feng, C Gerarduzzi |
International journal of molecular sciences | 2020 |
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Strategies for regulating tissue fibrosis and their clinical application
M Kuwana |
Inflammation and Regeneration | 2020 |
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Impaired Myofibroblast Dedifferentiation Contributes to Nonresolving Fibrosis in Aging
K Kato, NJ Logsdon, YJ Shin, S Palumbo, A Knox, JD Irish, SP Rounseville, SR Rummel, M Mohamed, K Ahmad, JM Trinh, D Kurundkar, KS Knox, VJ Thannickal, L Hecker |
American journal of respiratory cell and molecular biology | 2020 |
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Adaptive and innate immune mechanisms in cardiac fibrosis complicating pulmonary arterial hypertension
JH Siamwala, A Zhao, H Barthel, FS Pagano, RJ Gilbert, S Rounds |
Physiological Reports | 2020 |
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Airway epithelial specific deletion of Jun-N-terminal kinase 1 attenuates pulmonary fibrosis in two independent mouse models
JL van der Velden, JF Alcorn, DG Chapman, LK Lundblad, CG Irvin, RJ Davis, K Butnor, YM Janssen-Heininger, W Shi |
PloS one | 2020 |
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A Potential Theragnostic Regulatory Axis for Arthrofibrosis Involving Adiponectin (ADIPOQ) Receptor 1 and 2 (ADIPOR1 and ADIPOR2), TGFβ1, and Smooth Muscle α-Actin (ACTA2)
B Bayram, AR Owen, A Dudakovic, L Dagneaux, TW Turner, JW Bettencourt, AK Limberg, ME Tibbo, ME Morrey, J Sanchez-Sotelo, DJ Berry, JP Kocher, AJ van Wijnen, MP Abdel |
Journal of Clinical Medicine | 2020 |
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Anti-fibrotic Actions of Equine Interleukin-10 on Transforming Growth Factor-Beta1-Stimulated Dermal Fibroblasts Isolated From Limbs of Horses
LM Wise, GS Stuart, K Sriutaisuk, BR Adams, CB Riley, CL Theoret |
Frontiers in Veterinary Science | 2020 |
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Immunomodulatory and Regenerative Effects of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Renal Diseases
K Tsuji, S Kitamura, J Wada |
International journal of molecular sciences | 2020 |
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Biocompatibility of a Marine Collagen-Based Scaffold In Vitro and In Vivo
D Benayahu, L Pomeraniec, S Shemesh, S Heller, Y Rosenthal, L Rath-Wolfson, Y Benayahu |
Marine drugs | 2020 |
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Non-Invasive Monitoring of Oxygen Tension and Oxygen Transport Inside Subcutaneous Devices After H 2 S Treatment
A Najdahmadi, AM Smink, P de Vos, JR Lakey, E Botvinick |
Cell Transplantation | 2020 |
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Chronic Kidney Disease
MS Goligorsky |
The American Journal of Pathology | 2020 |
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Vactosertib, a Novel, Orally Bioavailable Activin Receptor-Like Kinase 5 Inhibitor, Promotes Regression of Fibrotic Plaques in a Rat Model of Peyronie's Disease
KM Song, DY Chung, MJ Choi, K Ghatak, NN Minh, A Limanjaya, MH Kwon, J Ock, GN Yin, DK Kim, JK Ryu, JK Suh |
The World Journal of Men's Health | 2020 |
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Spin‐lock relaxation rate dispersion reveals spatiotemporal changes associated with tubulointerstitial fibrosis in murine kidney
F Wang, DC Colvin, S Wang, H Li, Z Zu, RC Harris, MZ Zhang, JC Gore |
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine | 2020 |
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An integrated multiomic and quantitative label-free microscopy-based approach to study pro-fibrotic signalling in ex vivo human precision-cut lung slices
MM Khan, D Poeckel, A Halavatyi, J Zukowska-Kasprzyk, F Stein, J Vappiani, DC Sevin, C Tischer, N Zinn, JD Eley, NS Gudmann, T Muley, H Winter, AJ Fisher, CB Nanthakumar, G Bergamini, R Pepperkok |
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology | 2020 |
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Lumican promotes joint fibrosis through TGF‐β signaling
D Xiao, T Liang, Z Zhuang, R He, J Ren, S Jiang, L Zhu, K Wang, D Shi |
FEBS Open Bio | 2020 |
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Dynamic High-Sensitivity Quantitation of Procollagen-I by Endogenous CRISPR-Cas9 NanoLuciferase Tagging
BC Calverley, KE Kadler, A Pickard |
Cells | 2020 |
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Effects of New NSAID-CAI Hybrid Compounds in Inflammation and Lung Fibrosis
L Lucarini, M Durante, S Sgambellone, C Lanzi, E Bigagli, O Akgul, E Masini, CT Supuran, F Carta |
Biomolecules | 2020 |
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Molecular Mechanisms to Target Cellular Senescence in Hepatocellular Carcinoma
C Mittermeier, A Konopa, S Muehlich |
Cells | 2020 |
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A Systematic Review of the Pharmacology, Toxicology and Pharmacokinetics of Matrine
L You, C Yang, Y Du, W Wang, M Sun, J Liu, B Ma, L Pang, Y Zeng, Z Zhang, X Dong, X Yin, J Ni |
Frontiers in pharmacology | 2020 |
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Efficient drug and gene delivery to liver fibrosis: rationale, recent advances, and perspectives
S Mahdinloo, SH Kiaie, A Amiri, S Hemmati, H Valizadeh, P Zakeri-Milani |
Acta pharmaceutica Sinica. B | 2020 |
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Predictive Value of Precision-Cut Kidney Slices as an Ex Vivo Screening Platform for Therapeutics in Human Renal Fibrosis
E Bigaeva, NP Cavanzo, EG Stribos, AJ de Jong, C Biel, HA Mutsaers, MS Jensen, R Nørregaard, AM Leliveld, IJ de Jong, JL Hillebrands, H van Goor, M Boersema, RA Bank, P Olinga |
Pharmaceutics | 2020 |
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The In Vitro Inhibitory Effect of Sivelestat on Elastase Induced Collagen and Metallopeptidase Expression in Equine Endometrium
A Amaral, C Fernandes, MR Rebordão, A Szóstek-Mioduchowska, K Lukasik, B Gawronska-Kozak, LT da Gama, DJ Skarzynski, G Ferreira-Dias |
Animals | 2020 |
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Oxetanyl Sulfoxide MMS-350 Ameliorates Pulmonary Fibrosis In Vitro , In Vivo , and Ex Vivo
L Mlakar, J Lane, T Takihara, C Lim, MM Sprachman, KR Lloyd, P Wipf, C Feghali-Bostwick |
ACS Medicinal Chemistry Letters | 2020 |
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Whole Slide Imaging and Its Applications to Histopathological Studies of Liver Disorders
RC Melo, MW Raas, C Palazzi, VH Neves, KK Malta, TP Silva |
Frontiers in Medicine | 2020 |
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Urine-Derived Stem Cells: Applications in Regenerative and Predictive Medicine
G Bento, AK Shafigullina, AA Rizvanov, VA Sardão, MP Macedo, PJ Oliveira |
Cells | 2020 |
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Predictors for Submucosal Fibrosis in Patients With Superficial Squamous Esophageal Neoplasia Undergoing Endoscopic Submucosal Dissection
X Zhuang, M Xu, Z Chen, J Wang, K Qian, S Wang, G Deng, Y Bai |
Clinical and Translational Gastroenterology | 2020 |
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Diverse Injury Pathways Induce Alveolar Epithelial Cell CCL2/12, Which Promotes Lung Fibrosis
J Yang, M Agarwal, S Ling, S Teitz-Tennenbaum, RL Zemans, JJ Osterholzer, TH Sisson, KK Kim |
American journal of respiratory cell and molecular biology | 2020 |
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Role of Cyclosporine in Gingival Hyperplasia: An In Vitro Study on Gingival Fibroblasts
D Lauritano, A Palmieri, A Lucchese, DD Stasio, G Moreo, F Carinci |
International journal of molecular sciences | 2020 |
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Stimulation of Fibronectin Matrix Assembly by Lysine Acetylation
ME Vega, B Kastberger, B Wehrle-Haller, JE Schwarzbauer |
Cells | 2020 |
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Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis
AE John, RH Graves, KT Pun, G Vitulli, EJ Forty, PF Mercer, JL Morrell, JW Barrett, RF Rogers, M Hafeji, LI Bibby, E Gower, VS Morrison, Y Man, JA Roper, JC Luckett, LA Borthwick, BS Barksby, RA Burgoyne, R Barnes, J Le, DJ Flint, S Pyne, A Habgood, LA Organ, C Joseph, RC Edwards-Pritchard, TM Maher, AJ Fisher, NS Gudmann, DJ Leeming, RC Chambers, PT Lukey, RP Marshall, SJ Macdonald, RG Jenkins, RJ Slack |
Nature Communications | 2020 |
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Towards extracellular matrix normalization for improved treatment of solid tumors
HS Abyaneh, M Regenold, TD McKee, C Allen, MA Gauthier |
Theranostics | 2020 |
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Evolving therapies for Peyronie’s disease: how can we work towards new drugs?
U Milenkovic, J Duponselle, T Bivalacqua, M Albersen |
Translational andrology and urology | 2020 |
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Self-eating: friend or foe? The emerging role of autophagy in fibrotic diseases
Y Li, R Liu, J Wu, X Li |
Theranostics | 2020 |
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Hair regrowth in 2 patients with recalcitrant central centrifugal cicatricial alopecia after use of topical metformin.
Araoye EF, Thomas JAL, Aguh CU |
JAAD Case Reports | 2020 |
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Cross-talk between microRNA-let7c and transforming growth factor-β2 during epithelial-to-mesenchymal transition of retinal pigment epithelial cells.
Deji QZ, Yan F, Zhaba WD, Liu YJ, Yin J, Huang ZP |
International Journal of Ophthalmology | 2020 |
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Inhibition of miRNA‑135a‑5p ameliorates TGF‑β1‑induced human renal fibrosis by targeting SIRT1 in diabetic nephropathy.
Zhang J, Zhang L, Zha D, Wu X |
International journal of molecular medicine | 2020 |
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Matrix metalloproteinase-degraded type I collagen is associated with APOE/TOMM40 variants and preclinical dementia
Tang MH, Blair JP, Bager CL, Bay-Jensen AC, Henriksen K, Christiansen C, Karsdal MA |
2020 | |
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A hierarchical network of hypoxia-inducible factor and SMAD proteins governs procollagen lysyl hydroxylase 2 induction by hypoxia and transforming growth factor β1
T Rosell-García, O Palomo-Álvarez, F Rodríguez-Pascual |
The Journal of biological chemistry | 2019 |
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The Role of Pathological Aging in Cardiac and Pulmonary Fibrosis
LA Murtha, M Morten, MJ Schuliga, NS Mabotuwana, SA Hardy, DW Waters, JK Burgess, DT Ngo, AL Sverdlov, DA Knight, AJ Boyle |
Aging and disease | 2019 |
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Three in a Box: Understanding Cardiomyocyte, Fibroblast, and Innate Immune Cell Interactions to Orchestrate Cardiac Repair Processes
S Psarras, D Beis, S Nikouli, M Tsikitis, Y Capetanaki |
Frontiers in Cardiovascular Medicine | 2019 |
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Therapeutic Targeting of Fibrotic Epithelial-Mesenchymal Transition–An Outstanding Challenge
A Fintha, Á Gasparics, L Rosivall, A Sebe |
Frontiers in pharmacology | 2019 |
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Participation of the SMAD2/3 signalling pathway in the down regulation of megalin/LRP2 by transforming growth factor beta (TGF-ß1)
F Cabezas, P Farfán, MP Marzolo, A Ahmad |
PloS one | 2019 |
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Regulation of Immune Function by the Lymphatic System in Lymphedema
RP Kataru, JE Baik, HJ Park, I Wiser, S Rehal, JY Shin, BJ Mehrara |
Frontiers in immunology | 2019 |
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Fibrosis and secondary lymphedema: chicken or egg?
RP Kataru, I Wiser, JE Baik, HJ Park, S Rehal, JY Shin, BJ Mehrara |
Translational research : the journal of laboratory and clinical medicine | 2019 |
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Potential Role of the Resident Mesenchymal Stem-Like Cells in Renal Fibrogenesis after Ureteral Obstruction
YH Peng, J Xiao, C Yan, L Luo, TS Li |
Stem Cells International | 2019 |
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Secretory immunoglobulin A induces human lung fibroblasts to produce inflammatory cytokines and undergo activation: Secretory IgA activates human lung fibroblasts
S Arakawa, M Suzukawa, K Watanabe, K Kobayashi, H Matsui, H Nagai, T Nagase, K Ohta |
Clinical & Experimental Immunology | 2019 |
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Dysregulation of Mesenchymal Cell Survival Pathways in Severe Fibrotic Lung Disease: The Effect of Nintedanib Therapy
RK Kasam, GB Reddy, AG Jegga, SK Madala |
Frontiers in pharmacology | 2019 |
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The Molecular Mechanism of Transforming Growth Factor-β Signaling for Intestinal Fibrosis: A Mini-Review
SM Yun, SH Kim, EH Kim |
Frontiers in pharmacology | 2019 |
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Collagen: Methods and Protocols
I Sagi, NA Afratis |
2019 | |
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Human Amnion Epithelial Cell Therapy for Chronic Liver Disease
N Andrewartha, G Yeoh |
Stem Cells International | 2019 |
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Febuxostat inhibits TGF‑β1‑induced epithelial‑mesenchymal transition via downregulation of USAG‑1 expression in Madin‑Darby canine kidney cells in�vitro
L Lu, J Zhu, Y Zhang, Y Wang, S Zhang, A Xia |
Molecular medicine reports | 2019 |
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HDAC inhibitors as antifibrotic drugs in cardiac and pulmonary fibrosis
X Lyu, M Hu, J Peng, X Zhang, YY Sanders |
Therapeutic Advances in Chronic Disease | 2019 |
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Pancreatic stellate cells in the islets as a novel target to preserve the pancreatic β‐cell mass and function
Y Yang, JW Kim, HS Park, EY Lee, KH Yoon |
Journal of Diabetes Investigation | 2019 |
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Sphingolipids as Emerging Mediators in Retina Degeneration
MV Simón, FH Spalm, MS Vera, NP Rotstein |
Frontiers in cellular neuroscience | 2019 |
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LGM2605 Reduces Space Radiation-Induced NLRP3 Inflammasome Activation and Damage in In Vitro Lung Vascular Networks
S Chatterjee, R Pietrofesa, K Park, JQ Tao, A Carabe-Fernandez, A Berman, C Koumenis, T Sielecki, M Christofidou-Solomidou |
International journal of molecular sciences | 2019 |
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lncRNA H19 prevents endothelial–mesenchymal transition in diabetic retinopathy
AA Thomas, S Biswas, B Feng, S Chen, J Gonder, S Chakrabarti |
Diabetologia | 2019 |
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Tumor-stromal crosstalk in pancreatic cancer and tissue fibrosis
D Thomas, P Radhakrishnan |
Molecular Cancer | 2019 |
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A Human Skin Model Recapitulates Systemic Sclerosis Dermal Fibrosis and Identifies COL22A1 as a TGFβ Early Response Gene that Mediates Fibroblast to Myofibroblast Transition
T Watanabe, DA Frost, L Mlakar, J Heywood, WA da Silveira, G Hardiman, C Feghali-Bostwick |
Genes & development | 2019 |
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Salvianolic Acids: Potential Source of Natural Drugs for the Treatment of Fibrosis Disease and Cancer
L Ma, L Tang, Q Yi |
Frontiers in pharmacology | 2019 |
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Effects of PARP-1 Deficiency and Histamine H4 Receptor Inhibition in an Inflammatory Model of Lung Fibrosis in Mice
M Durante, S Sgambellone, C Lanzi, P Nardini, A Pini, F Moroni, E Masini, L Lucarini |
Frontiers in pharmacology | 2019 |
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Evaluation of the use of tacrolimus ointment for the prevention of hypertrophic scars in experimental model
MC Menezes, L de Souza Vasconcellos, CB Nunes, LR Alberti |
Anais Brasileiros de Dermatologia | 2019 |
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Intracellular Heat Shock Protein 70 Deficiency in Pulmonary Fibrosis
J Sellares, KL Veraldi, KJ Thiel, N Cárdenes, D Alvarez, F Schneider, JM Pilewski, M Rojas, CA Feghali-Bostwick |
American journal of respiratory cell and molecular biology | 2019 |
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mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-β 1 –induced collagen biosynthesis
B Selvarajah, I Azuelos, M Platé, D Guillotin, EJ Forty, G Contento, HV Woodcock, M Redding, A Taylor, G Brunori, PF Durrenberger, R Ronzoni, AD Blanchard, PF Mercer, D Anastasiou, RC Chambers |
Science signaling | 2019 |
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The Role of Mesenchymal Stem Cells in Radiation-Induced Lung Fibrosis
Zanoni, Cortesi, Zamagni, Tesei |
International journal of molecular sciences | 2019 |
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Eosinophils and Macrophages within the Th2-Induced Granuloma: Balancing Killing and Healing in a Tight Space
A Ariyaratne, CA Finney, AJ Bäumler |
Infection and immunity | 2019 |
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Cardiac Fibroblast to Myofibroblast Phenotype Conversion—An Unexploited Therapeutic Target
Czubryt |
Journal of Cardiovascular Development and Disease | 2019 |
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Targeting Fibrotic Signaling: A Review of Current Literature and Identification of Future Therapeutic Targets to Improve Wound Healing
PT Hetzler, BC Dash, S Guo, HC Hsia |
Annals of Plastic Surgery | 2019 |
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Application of nintedanib and other potential anti-fibrotic agents in fibrotic diseases
F Liu, G Bayliss, S Zhuang |
Clinical Science | 2019 |
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A Matricryptic Conformation of the Integrin-Binding Domain of Fibronectin Regulates Platelet-Derived Growth Factor-Induced Intracellular Calcium Release
CS Farrar, GT Rouin, BL Miller, CH Raeman, NA Mooney, DC Hocking |
Cells | 2019 |
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Kangfuxin Oral Liquid Attenuates Bleomycin-Induced Pulmonary Fibrosis via the TGF- β 1/Smad Pathway
H Yao, S Wei, Y Xiang, Z Wu, W Liu, B Wang, X Li, H Xu, J Zhao, Y Gao |
Evidence-Based Complementary and Alternative Medicine | 2019 |
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FibroAtlas: A Database for the Exploration of Fibrotic Diseases and Their Genes
J Liu, D Sun, J Liu, H Xu, Y Liu, Y Li, L Diao, X Wang, D Wang, L Tian, H Zhang, Z Liu, W Ren, F He, D Li, S Guo |
Cardiology Research and Practice | 2019 |
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Renoprotective effects of a novel cMet agonistic antibody on kidney fibrosis
YC Kim, J Lee, JN An, JH Kim, YW Choi, L Li, SH Kwon, MY Lee, B Lee, JG Jeong, SS Yu, CS Lim, YS Kim, S Kim, SH Yang, JP Lee |
Scientific Reports | 2019 |
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Alpha-Mangostin Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice Partly Through Activating Adenosine 5′-Monophosphate-Activated Protein Kinase
R Li, G Xu, J Cao, B Liu, H Xie, Y Ishii, C Zhang |
Frontiers in pharmacology | 2019 |
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Noninvasive quantitative magnetization transfer MRI reveals tubulointerstitial fibrosis in murine kidney
F Wang, S Wang, Y Zhang, K Li, RC Harris, JC Gore, MZ Zhang |
NMR in Biomedicine | 2019 |
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Comparison of laboratory indices of non-alcoholic fatty liver disease for the detection of incipient kidney dysfunction.
Choi JW, Lee CH, Park JS |
PeerJ | 2019 |
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Early laparoscopic cholecystectomy is associated with less risk of complications after the removal of common bile duct stones by endoscopic retrograde cholangiopancreatography.
Aziret M, Karaman K, Ercan M, Vargöl E, Toka B, Arslan Y, Öter V, Bostancı EB, Parlak E |
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology | 2019 |
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Intratunical injection of autologous adipose stromal vascular fraction reduces collagen III expression in a rat model of chronic penile fibrosis.
Hakim L, Fiorenzo S, Hedlund P, Montorsi F, Bivalacqua TJ, De Ridder D, Weyne E, Ralph D, Garaffa G, Muneer A, Joniau S, Albersen M, Castiglione F |
International Journal of Impotence Research | 2019 |
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Prospective application of stem cells to prevent post-operative skeletal fibrosis
Li X, Chen S, Yan L, Wang J, Pei M |
Journal of orthopaedic research : official publication of the Orthopaedic Research Society | 2019 |
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MicroRNA 27b promotes cardiac fibrosis by targeting the FBW7/Snail pathway.
Fu Q, Lu Z, Fu X, Ma S, Lu X |
Aging | 2019 |
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Mechanosensing and fibrosis
Daniel J. Tschumperlin, Giovanni Ligresti, Moira Hilscher, Vijay H. Shah |
Journal of Clinical Investigation | 2018 |
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Endoplasmic reticulum stress in the pathogenesis of fibrotic disease
Jon Kropski, Timothy Blackwell |
Journal of Clinical Investigation | 2018 |
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Fatty acid synthase is required for profibrotic TGF-β signaling
MY Jung, JH Kang, DM Hernandez, X Yin, M Andrianifahanana, Y Wang, A Gonzalez-Guerrico, AH Limper, R Lupu, EB Leof |
The FASEB Journal | 2018 |
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Macrophage migration inhibitory factor contributes to the pathogenesis of benign lymphoepithelial lesion of the lacrimal gland
YM Adzavon, P Zhao, J Ma, X Zhang, X Zhang, M Zhang, M Liu, L Wang, D Chen, TG Abisso, B Lv, L Wang, F Xie, X Ma |
Cell Communication and Signaling | 2018 |
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FK506-binding protein 10 (FKBP10) regulates lung fibroblast migration via collagen VI synthesis
L Knüppel, K Heinzelmann, M Lindner, R Hatz, J Behr, O Eickelberg, CA Staab-Weijnitz |
Respiratory Research | 2018 |
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Immune mechanisms in the different phases of acute tubular necrosis
F Kundert, L Platen, T Iwakura, Z Zhao, JA Marschner, HJ Anders |
Kidney Research and Clinical Practice | 2018 |
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Intermediate filaments in cardiomyopathy
M Tsikitis, Z Galata, M Mavroidis, S Psarras, Y Capetanaki |
Biophysical Reviews | 2018 |
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Discoidin Domain Receptor 2 Signaling Regulates Fibroblast Apoptosis Through PDK1/Akt
S Jia, M Agarwal, J Yang, JC Horowitz, ES White, KK Kim |
American journal of respiratory cell and molecular biology | 2018 |
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Abrogation of transforming growth factor-β-induced tissue fibrosis in TBRIcaCol1a2Cre transgenic mice by the second generation tyrosine kinase inhibitor SKI-606 (Bosutinib)
PJ Wermuth, SA Jimenez, D Gullberg |
PloS one | 2018 |
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Limited fibrosis accompanies triple-negative breast cancer metastasis in multiple model systems and is not a preventive target
D Brooks, A Zimmer, L Wakefield, LT Lyle, S Difilippantonio, FC Tucci, S Illiano, CM Annunziata, PS Steeg |
Oncotarget | 2018 |
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Targeting Senescent Cells in Fibrosis: Pathology, Paradox, and Practical Considerations
MJ Schafer, AJ Haak, DJ Tschumperlin, NK LeBrasseur |
Current Rheumatology Reports | 2018 |
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The diversity of myeloid immune cells shaping wound repair and fibrosis in the lung
L Florez-Sampedro, S Song, BN Melgert |
Regeneration | 2018 |
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Tryptophan metabolites kynurenine and serotonin regulate fibroblast activation and fibrosis
DM Dolivo, SA Larson, T Dominko |
Cellular and Molecular Life Sciences | 2018 |
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Epithelial-stromal crosstalk and fibrosis in eosinophilic esophagitis
AB Muir, JX Wang, H Nakagawa |
Journal of Gastroenterology | 2018 |
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Flavanones from Sedum sarmentosum Bunge Alleviate CCl 4 -Induced Liver Fibrosis in Rats by Targeting TGF- β 1/T β R/Smad Pathway In Turn Inhibiting Epithelial Mesenchymal Transition
Y Lin, H Luo, X Wang, M Zheng, Q Jin, H Chen, P Pan, J Zhang |
Evidence-Based Complementary and Alternative Medicine | 2018 |
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Antifibrotic effects of gallic acid on hepatic stellate cells: In vitro and in vivo mechanistic study
NM El-Lakkany, WH El-Maadawy, SH el-Din, S Saleh, MM Safar, SM Ezzat, SH Mohamed, SS Botros, Z Demerdash, OA Hammam |
Journal of traditional and complementary medicine | 2018 |
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Pilot study of the antifibrotic effects of the multikinase inhibitor pacritinib in a mouse model of liver fibrosis
S Al-Fayoumi, T Hashiguchi, Y Shirakata, J Mascarenhas, JW Singer |
Journal of Experimental Pharmacology | 2018 |
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Global Gene Expression Analysis in an in vitro Fibroblast Model of Idiopathic Pulmonary Fibrosis Reveals Potential Role for CXCL14/CXCR4
LR Rodriguez, M Emblom-Callahan, M Chhina, S Bui, B Aljeburry, LH Tran, R Novak, M Lemma, SD Nathan, GM Grant |
Scientific Reports | 2018 |
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IL-17 in Peritoneal Dialysis-Associated Inflammation and Angiogenesis: Conclusions and Perspectives
J Witowski, J Kamhieh-Milz, E Kawka, R Catar, A Jörres |
Frontiers in physiology | 2018 |
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Involvement of the ubiquitin-proteasome system in the expression of extracellular matrix genes in retinal pigment epithelial cells
JE de Carvalho, MT Verwoert, IM Vogels, EA Reits, CJ Noorden, I Klaassen, RO Schlingemann |
Biochemistry and Biophysics Reports | 2018 |
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Stem Cell Differentiation is Regulated by Extracellular Matrix Mechanics
LR Smith, S Cho, DE Discher |
Physiology (Bethesda, Md.) | 2018 |
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Angiopoietin-1 deficiency increases renal capillary rarefaction and tubulointerstitial fibrosis in mice
K Loganathan, ES Said, E Winterrowd, M Orebrand, L He, M Vanlandewijck, C Betsholtz, SE Quaggin, M Jeansson, D Long |
PloS one | 2018 |
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Emerging role of Twist1 in fibrotic diseases
X Ning, K Zhang, Q Wu, M Liu, S Sun |
Journal of Cellular and Molecular Medicine | 2018 |
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CD4+ T cells are activated in regional lymph nodes and migrate to skin to initiate lymphedema
GD Nores, CL Ly, DA Cuzzone, RP Kataru, GE Hespe, JS Torrisi, JJ Huang, JC Gardenier, IL Savetsky, MD Nitti, JZ Yu, S Rehal, BJ Mehrara |
Nature Communications | 2018 |
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The family of 14-3-3 proteins and specifically 14-3-3σ are up-regulated during the development of renal pathologies
M Rizou, EA Frangou, F Marineli, N Prakoura, J Zoidakis, H Gakiopoulou, G Liapis, P Kavvadas, C Chatziantoniou, M Makridakis, A Vlahou, J Boletis, D Vlahakos, D Goumenos, E Daphnis, C Iatrou, AS Charonis |
Journal of Cellular and Molecular Medicine | 2018 |
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Metabolic syndrome and extensive adipose tissue inflammation in morbidly obese Göttingen minipigs
S Renner, A Blutke, B Dobenecker, G Dhom, TD Müller, B Finan, C Clemmensen, M Bernau, I Novak, B Rathkolb, S Senf, S Zöls, M Roth, A Götz, SM Hofmann, MH de Angelis, R Wanke, E Kienzle, AM Scholz, R DiMarchi, M Ritzmann, MH Tschöp, E Wolf |
Molecular Metabolism | 2018 |
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LncRNAs: Proverbial Genomic “Junk” or Key Epigenetic Regulators During Cardiac Fibrosis in Diabetes?
S Biswas, AA Thomas, S Chakrabarti |
Frontiers in Cardiovascular Medicine | 2018 |
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Development and Characterization of an In Vitro Model for Radiation-Induced Fibrosis
D Kumar, S Yalamanchali, J New, S Parsel, N New, A Holcomb, S Gunewardena, O Tawfik, C Lominska, BF Kimler, S Anant, K Kakarala, T Tsue, Y Shnayder, K Sykes, S Padhye, SM Thomas |
Radiation Research | 2018 |
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Fibroproliferative genes are preferentially expressed in central centrifugal cicatricial alopecia
C Aguh, Y Dina, CC Talbot, L Garza |
Journal of the American Academy of Dermatology | 2018 |
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Circulating CD34+ hematopoietic stem/progenitor cells paralleled with level of viremia in patients chronically infected with hepatitis B virus
H Abdellatif |
Regenerative Medicine Research | 2018 |
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Bimodal fluorogenic sensing of matrix proteolytic signatures in lung cancer
A Megia-Fernandez, B Mills, C Michels, SV Chankeshwara, N Krstajić, C Haslett, K Dhaliwal, M Bradley |
Organic & Biomolecular Chemistry | 2018 |
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Beyond the Matrix: The Many Non-ECM Ligands for Integrins
B LaFoya, J Munroe, A Miyamoto, M Detweiler, J Crow, T Gazdik, A Albig |
International journal of molecular sciences | 2018 |
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Control of cellular adhesion and myofibroblastic character with sub-micrometer magnetoelastic vibrations
HR Holmes, E Vlaisavljevich, EL Tan, KL Snyder, KG Ong, RM Rajachar |
Journal of Biomechanics | 2018 |
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Ambiguous roles of innate lymphoid cells in chronic development of liver diseases
Y Shen, J Li, SQ Wang, W Jiang |
World journal of gastroenterology : WJG | 2018 |
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Painful Terminal Neuroma Prevention by Capping PRGD/PDLLA Conduit in Rat Sciatic Nerves
J Yi, N Jiang, B Li, Q Yan, T Qiu, KS Iyer, Y Yin, H Dai, AK Yetisen, S Li |
Advanced Science | 2018 |
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Understanding deregulated cellular and molecular dynamics in the haematopoietic stem cell niche to develop novel therapeutics for bone marrow fibrosis: The haematopoietic stem cell niche in bone marrow fibrosis
HF Gleitz, R Kramann, RK Schneider |
The Journal of Pathology | 2018 |
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Loss of periostin occurs in aging adipose tissue of mice and its genetic ablation impairs adipose tissue lipid metabolism
A Graja, F Garcia-Carrizo, AM Jank, S Gohlke, TH Ambrosi, W Jonas, S Ussar, M Kern, A Schürmann, K Aleksandrova, M Blüher, TJ Schulz |
Aging Cell | 2018 |
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Significance of Intratumoral Fibrosis in Clear Cell Renal Cell Carcinoma
JW Joung, HK Oh, SJ Lee, YA Kim, HJ Jung |
Journal of Pathology and Translational Medcine | 2018 |
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Luteolin Targets the Toll-Like Receptor Signaling Pathway in Prevention of Hepatic and Adipocyte Fibrosis and Insulin Resistance in Diet-Induced Obese Mice
EY Kwon, MS Choi |
Nutrients | 2018 |
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Non-Canonical Regulation of Type I Collagen through Promoter Binding of SOX2 and Its Contribution to Ameliorating Pulmonary Fibrosis by Butylidenephthalide
HM Chuang, LI Ho, MH Huang, KL Huang, TW Chiou, SZ Lin, HL Su, HJ Harn |
International journal of molecular sciences | 2018 |
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Serum-Free Medium Enhances the Immunosuppressive and Antifibrotic Abilities of Mesenchymal Stem Cells Utilized in Experimental Renal Fibrosis: Serum-Free MSCs Enhance Immunosuppressive Effects
K Yoshida, A Nakashima, S Doi, T Ueno, T Okubo, K Kawano, M Kanawa, Y Kato, Y Higashi, T Masaki |
Stem Cells Translational Medicine | 2018 |
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PD-L1 Expression on Circulating CD34＋ Hematopoietic Stem Cells Closely Correlated with T-cell Apoptosis in Chronic Hepatitis C Infected Patients
H Abdellatif, G Shiha |
International journal of stem cells | 2018 |
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Established and novel pathophysiological mechanisms of pericardial injury and constrictive pericarditis
Ramasamy V, Mayosi BM, Sturrock ED, Ntsekhe M |
World journal of cardiology | 2018 |
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Crosstalk between mitogen-activated protein kinase inhibitors and transforming growth factor-β signaling results in variable activation of human dermal fibroblasts
Dolivo DM, Larson SA, Dominko T |
International journal of molecular medicine | 2018 |
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Circulating markers of collagen types I, III, and IV in patients with dilated cardiomyopathy: relationships with myocardial collagen expression
Nagao K, Inada T, Tamura A, Kajitani K, Shimamura K, Yukawa H, Aida K, Sowa N, Nishiga M, Horie T, Makita T, Ono K, Tanaka M |
ESC Heart Failure | 2018 |
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Intratunical Injection of Human Adipose Tissue–Derived Stem Cells Restores Collagen III/I Ratio in a Rat Model of Chronic Peyronie’s Disease
Castiglione F, Hedlund P, Weyne E, Hakim L, Montorsi F, Bivalacqua TJ, De Ridder D, Milenkovic U, Ralph D, Garaffa G, Muneer A, Joniau S, Albersen M |
Sexual Medicine | 2018 |
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Dynamics of cellular states of fibro-adipogenic progenitors during myogenesis and muscular dystrophy.
Malecova B, Gatto S, Etxaniz U, Passafaro M, Cortez A, Nicoletti C, Giordani L, Torcinaro A, De Bardi M, Bicciato S, De Santa F, Madaro L, Puri PL |
Nature Communications | 2018 |
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New transgenic NIS reporter rats for longitudinal tracking of fibrogenesis by high-resolution imaging.
Brunton B, Suksanpaisan L, Li H, Liu Q, Yu Y, Vrieze A, Zhang L, Jenks N, Jiang H, DeGrado TR, Zhao C, Russell SJ, Peng KW |
Scientific Reports | 2018 |
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Inhibition of Profibrotic Smad3 Action by Cell Penetrating Peptides
Jeong-Han Kang, Mi-Yeon Jung, Xueqian Yin, Mahefatiana Andrianifahanana, Danielle Hernandez, Edward B. Leof |
Journal of Clinical Investigation | 2017 |
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Emerging therapies for idiopathic pulmonary fibrosis, a progressive age-related disease
AL Mora, M Rojas, A Pardo, M Selman |
Nature Reviews Drug Discovery | 2017 |
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Emerging therapies for idiopathic pulmonary fibrosis, a progressive age-related disease
AL Mora, M Rojas, A Pardo, M Selman |
Nature Reviews Drug Discovery | 2017 |
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European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)
J Egea, I Fabregat, YM Frapart, P Ghezzi, A Görlach, T Kietzmann, K Kubaichuk, UG Knaus, MG Lopez, G Olaso-Gonzalez, A Petry, R Schulz, J Vina, P Winyard, K Abbas, OS Ademowo, CB Afonso, I Andreadou, H Antelmann, F Antunes, M Aslan, MM Bachschmid, RM Barbosa, V Belousov, C Berndt, D Bernlohr, E Bertrán, A Bindoli, SP Bottari, PM Brito, G Carrara, AI Casas, A Chatzi, N Chondrogianni, M Conrad, MS Cooke, JG Costa, A Cuadrado, PM Dang, BD Smet, B DebelecButuner, IH Dias, JD Dunn, AJ Edson, ME Assar, J El-Benna, P Ferdinandy, AS Fernandes, KE Fladmark, U Förstermann, R Giniatullin, Z Giricz, A Görbe, H Griffiths, V Hampl, A Hanf, J Herget, P Hernansanz-Agustín, M Hillion, J Huang, S Ilikay, P Jansen-Dürr, V Jaquet, JA Joles, B Kalyanaraman, D Kaminskyy, M Karbaschi, M Kleanthous, LO Klotz, B Korac, KS Korkmaz, R Koziel, D Kračun, KH Krause, V Křen, T Krieg, J Laranjinha, A Lazou, H Li, A Martínez-Ruiz, R Matsui, GJ McBean, SP Meredith, J Messens, V Miguel, Y Mikhed, I Milisav, L Milković, A Miranda-Vizuete, M Mojović, M Monsalve, PA Mouthuy, J Mulvey, T Münzel, V Muzykantov, IT Nguyen, M Oelze, NG Oliveira, CM Palmeira, N Papaevgeniou, A Pavićević, B Pedre, F Peyrot, M Phylactides, GG Pircalabioru, AR Pitt, HE Poulsen, I Prieto, MP Rigobello, N Robledinos-Antón, L Rodríguez-Mañas, AP Rolo, F Rousset, T Ruskovska, N Saraiva, S Sasson, K Schröder, K Semen, T Seredenina, A Shakirzyanova, GL Smith, T Soldati, BC Sousa, CM Spickett, A Stancic, MJ Stasia, H Steinbrenner, V Stepanić, S Steven, K Tokatlidis, E Tuncay, B Turan, F Ursini, J Vacek, O Vajnerova, K Valentová, FV Breusegem, L Varisli, EA Veal, AS Yalçın, O Yelisyeyeva, N Žarković, M Zatloukalová, J Zielonka, RM Touyz, A Papapetropoulos, T Grune, S Lamas, HH Schmidt, FD Lisa, A Daiber |
Redox Biology | 2017 |
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TGF-β1 Signaling and Tissue Fibrosis
KK Kim, D Sheppard, HA Chapman |
Cold Spring Harbor perspectives in biology | 2017 |
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Airway remodeling in asthma: what really matters
H Fehrenbach, C Wagner, M Wegmann |
Cell and Tissue Research | 2017 |
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Scleroderma keratinocytes promote fibroblast activation independent of transforming growth factor beta
SS McCoy, TJ Reed, CC Berthier, PS Tsou, J Liu, JE Gudjonsson, D Khanna, JM Kahlenberg |
Rheumatology | 2017 |
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Blockade of Bradykinin receptors worsens the dystrophic phenotype of mdx mice: differential effects for B1 and B2 receptors
MJ Acuña, D Salas, A Córdova-Casanova, M Cruz-Soca, C Céspedes, CP Vio, E Brandan |
Journal of Cell Communication and Signaling | 2017 |
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TGF-β-Induced Endothelial-Mesenchymal Transition in Fibrotic Diseases
E Pardali, G Sanchez-Duffhues, M Gomez-Puerto, P Dijke |
International journal of molecular sciences | 2017 |
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Baicalin ameliorates renal fibrosis via inhibition of transforming growth factor β1 production and downstream signal transduction
L Zheng, C Zhang, L Li, C Hu, M Hu, N Sidikejiang, X Wang, M Lin, R Rong |
Molecular medicine reports | 2017 |
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The antiviral drug tenofovir, an inhibitor of Pannexin-1-mediated ATP release, prevents liver and skin fibrosis by downregulating adenosine levels in the liver and skin
JL Feig, A Mediero, C Corciulo, H Liu, J Zhang, M Perez-Aso, L Picard, T Wilder, B Cronstein, MA Avila |
PloS one | 2017 |
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Selective activation of epidermal growth factor receptor in renal proximal tubule induces tubulointerstitial fibrosis
JM Overstreet, Y Wang, X Wang, A Niu, LS Gewin, B Yao, RC Harris, MZ Zhang |
The FASEB Journal | 2017 |
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Adipose tissue: between the extremes
A Vegiopoulos, M Rohm, S Herzig |
The EMBO Journal | 2017 |
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Transglutaminase 2 in human diseases
Z Szondy, I Korponay-Szabó, R Király, Z Sarang, GJ Tsay |
BioMedicine | 2017 |
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Overactive Epidermal Growth Factor Receptor Signaling Leads to Increased Fibrosis after Severe Acute Respiratory Syndrome Coronavirus Infection
T Venkataraman, CM Coleman, MB Frieman, TS Dermody |
Journal of virology | 2017 |
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Galectin-3 Inhibition by a Small-Molecule Inhibitor Reduces Both Pathological Corneal Neovascularization and Fibrosis
WS Chen, Z Cao, H Leffler, UJ Nilsson, N Panjwani |
Investigative ophthalmology & visual science | 2017 |
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Oxidative stress in cancer and fibrosis: Opportunity for therapeutic intervention with antioxidant compounds, enzymes, and nanoparticles
J Morry, W Ngamcherdtrakul, W Yantasee |
Redox Biology | 2017 |
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The use of urinary proteomics in the assessment of suitability of mouse models for ageing
E Nkuipou-Kenfack, JP Schanstra, S Bajwa, M Pejchinovski, C Vinel, C Dray, P Valet, JL Bascands, A Vlahou, T Koeck, M Borries, H Busch, W Bechtel-Walz, TB Huber, KL Rudolph, A Pich, H Mischak, P Zürbig, J Kim |
PloS one | 2017 |
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Basic Principles of Bioengineering and Regeneration
TL Aghaloo, D Hadaya |
Oral and Maxillofacial Surgery Clinics of North America | 2017 |
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Lysophosphatidic acid signaling through its receptor initiates profibrotic epithelial cell fibroblast communication mediated by epithelial cell derived connective tissue growth factor
N Sakai, J Chun, JS Duffield, D Lagares, T Wada, AD Luster, AM Tager |
Kidney International | 2017 |
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Adipose tissue fibrosis in human cancer cachexia: the role of TGFβ pathway
MJ Alves, RG Figuerêdo, FF Azevedo, DA Cavallaro, NI Neto, JD Lima, E Matos-Neto, K Radloff, DM Riccardi, RG Camargo, PS de Alcântara, JP Otoch, ML Batista, M Seelaender |
BMC Cancer | 2017 |
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Role of endothelial-to-mesenchymal transition induced by TGF-β1 in transplant kidney interstitial fibrosis
Z Wang, Z Han, J Tao, J Wang, X Liu, W Zhou, Z Xu, C Zhao, Z Wang, R Tan, M Gu |
Journal of Cellular and Molecular Medicine | 2017 |
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Selective measurement of α smooth muscle actin: why β-actin can not be used as a housekeeping gene when tissue fibrosis occurs
A Veres-Székely, D Pap, E Sziksz, E Jávorszky, R Rokonay, R Lippai, K Tory, A Fekete, T Tulassay, AJ Szabó, Á Vannay |
BMC Molecular Biology | 2017 |
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DNA Methylation Regulated Gene Expression in Organ Fibrosis
X Zhang, M Hu, X Lyu, C Li, VJ Thannickal, YY Sanders |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2017 |
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Preventing tissue fibrosis by local biomaterials interfacing of specific cryptic extracellular matrix information
CM Horejs, JP St-Pierre, JR Ojala, JA Steele, PB da Silva, A Rynne-Vidal, SA Maynard, CS Hansel, C Rodríguez-Fernández, MM Mazo, AY You, AJ Wang, T Erlach, K Tryggvason, M López-Cabrera, MM Stevens |
Nature Communications | 2017 |
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Matrix Mechanosensing: From Scaling Concepts in ’Omics Data to Mechanisms in the Nucleus, Regeneration, and Cancer
DE Discher, L Smith, S Cho, M Colasurdo, AJ García, S Safran |
Annual Review of Biophysics | 2017 |
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Optimization of a murine and human tissue model to recapitulate dermal and pulmonary features of systemic sclerosis
T Watanabe, T Nishimoto, L Mlakar, J Heywood, M Malaab, S Hoffman, C Feghali-Bostwick, AT Slominski |
PloS one | 2017 |
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Inhibition of CTGF ameliorates peritoneal fibrosis through suppression of fibroblast and myofibroblast accumulation and angiogenesis
N Sakai, M Nakamura, KE Lipson, T Miyake, Y Kamikawa, A Sagara, Y Shinozaki, S Kitajima, T Toyama, A Hara, Y Iwata, M Shimizu, K Furuichi, S Kaneko, AM Tager, T Wada |
Scientific Reports | 2017 |
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Fibroblast Growth Factor 2 as an Antifibrotic: Antagonism of Myofibroblast Differentiation and Suppression of Pro-Fibrotic Gene Expression
DM Dolivo, SA Larson, T Dominko |
Cytokine & Growth Factor Reviews | 2017 |
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Evidence of selection as a cause for racial disparities in fibroproliferative disease
JN Hellwege, ES Torstenson, SB Russell, TL Edwards, DR Edwards, G Sirugo |
PloS one | 2017 |
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Vitamin D supplementation improves serum markers associated with hepatic fibrogenesis in chronic hepatitis C patients: A randomized, double-blind, placebo-controlled study
P Komolmit, S Kimtrakool, S Suksawatamnuay, K Thanapirom, K Chattrasophon, P Thaimai, C Chirathaworn, Y Poovorawan |
Scientific Reports | 2017 |
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Role of the Wnt/β-catenin signaling pathway in inducing apoptosis and renal fibrosis in 5/6-nephrectomized rats
X Lin, Y Zha, XZ Zeng, R Dong, QH Wang, DT Wang |
Molecular medicine reports | 2017 |
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Transcriptome Identified lncRNAs Associated with Renal Fibrosis in UUO Rat Model
J Sun, S Zhang, B Shi, D Zheng, J Shi |
Frontiers in physiology | 2017 |
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Is There a Potential Therapeutic Role for Caveolin-1 in Fibrosis?
WA Shihata, MR Putra, JP Chin-Dusting |
Frontiers in pharmacology | 2017 |
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On the Cellular and Molecular Mechanisms of Drug-Induced Gingival Overgrowth
A Ramírez-Rámiz, L Brunet-LLobet, E Lahor-Soler, J Miranda-Rius |
The open dentistry journal | 2017 |
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New endoscopic approach of anti-fibrotic therapy for inflammatory bowel disease
K Suzuki, H Yoneyama |
Annals of translational medicine | 2017 |
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Reduction in skeletal muscle fibrosis of spontaneously hypertensive rats after laceration by microRNA targeting angiotensin II receptor
RS Stilhano, VY Samoto, LM Silva, GJ Pereira, AG Erustes, SS Smaili, SW Han, LE Quintas |
PloS one | 2017 |
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Editorial: Novel Therapeutic Targets and Emerging Treatments for Fibrosis
CS Samuel, TD Hewitson |
Frontiers in pharmacology | 2017 |
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Establishment of an indirect ELISA for detection of the novel antifibrotic peptide M10
T Akter, I Atanelishvili, A Noguchi, RM Silver, GS Bogatkevich, T Abraham |
PloS one | 2017 |
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Targeting Anti–TGF- β Therapy to Fibrotic Kidneys with a Dual Specificity Antibody Approach
S McGaraughty, RA Davis-Taber, CZ Zhu, TB Cole, AL Nikkel, M Chhaya, KJ Doyle, LM Olson, GM Preston, CM Grinnell, KM Salte, AM Giamis, Y Luo, V Sun, AD Goodearl, M Gopalakrishnan, SE Lacy |
Journal of the American Society of Nephrology : JASN | 2017 |
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A novel acetyltransferase p300 inhibitor ameliorates hypertension-associated cardio-renal fibrosis
R Rai, SK Verma, D Kim, V Ramirez, E Lux, C Li, S Sahoo, LD Wilsbacher, DE Vaughan, SE Quaggin, AK Ghosh |
Epigenetics : official journal of the DNA Methylation Society | 2017 |
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ω3-Polyunsaturated fatty acids for heart failure: Effects of dose on efficacy and novel signaling through free fatty acid receptor 4
TD O'Connell, RC Block, SP Huang, GC Shearer |
Journal of Molecular and Cellular Cardiology | 2017 |
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Myofibroblast in the ligamentum flavum hypertrophic activity.
Hur JW, Bae T, Ye S, Kim JH, Lee S, Kim K, Lee SH, Kim JS, Lee JB, Cho TH, Park JY, Hur JK |
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society | 2017 |
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Anti-TGFβ-1 receptor inhibitor mediates the efficacy of the human umbilical cord mesenchymal stem cells against liver fibrosis through TGFβ-1/Smad pathway.
Xuan J, Feng W, An ZT, Yang J, Xu HB, Li J, Zhao ZF, Wen W |
Molecular and Cellular Biochemistry | 2017 |
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Exosomes derived from human amniotic epithelial cells accelerate wound healing and inhibit scar formation.
Zhao B, Zhang Y, Han S, Zhang W, Zhou Q, Guan H, Liu J, Shi J, Su L, Hu D |
Journal Of Molecular Histology | 2017 |
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MicroRNA transcriptome analysis on hypertrophy of ligamentum flavum in patients with lumbar spinal stenosis.
Mori T, Sakai Y, Kayano M, Matsuda A, Oboki K, Matsumoto K, Harada A, Niida S, Watanabe K |
Spine Surgery and Related Research | 2017 |
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Evaluation of myofibroblasts in oral submucous fibrosis and oral squamous cell carcinoma: The pathogenesis and correlation
Gandhi P, Prasad UC |
Dental Research Journal | 2017 |
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Oligonucleotide-targeting periostin ameliorates pulmonary fibrosis.
Tomaru A, Kobayashi T, Hinneh JA, Baffour Tonto P, D'Alessandro-Gabazza CN, Fujimoto H, Fujiwara K, Takahashi Y, Ohnishi M, Yasuma T, Nishihama K, Yoshino M, Takao K, Toda M, Totoki T, Takei Y, Yoshikawa K, Taguchi O, Gabazza EC |
Gene Therapy | 2017 |
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Prolonged use of alendronate alters the biology of cranial repair in estrogen-deficient rats' associated simultaneous immunohistochemical expression of TGF-β1+, α-ER+, and BMPR1B.
Giovanini AF, de Sousa Passoni GN, Göhringer I, Deliberador TM, Zielak JC, Storrer CLM, Costa-Casagrande TA, Scariot R |
Clinical Oral Investigations | 2017 |
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Classical dendritic cells mediate fibrosis directly via the retinoic acid pathway, in severe eye allergy
Sarah Ahadome, Rose Mathew, Nancy Reyes, Priyatham Mettu, Scott Cousins, Virginia Calder, Daniel Saban |
JCI Insight | 2016 |
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IL4RA on lymphatic endothelial cells promotes T cell egress during Sclerodermatous Graft versus Host Disease
Katia Urso, david alvarez, Viviana Cremasco, Kelly Tsang, Angelo Grauel, Robert Lafyatis, Ulrich H von Andrian, Joerg Ermann, Antonios Aliprantis |
JCI Insight | 2016 |
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Inhibition of the Unfolded Protein Response Mechanism Prevents Cardiac Fibrosis
J Groenendyk, D Lee, J Jung, JR Dyck, GD Lopaschuk, LB Agellon, M Michalak, DY Jin |
PloS one | 2016 |
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TGF- β 1/Smads and miR-21 in Renal Fibrosis and Inflammation
A Loboda, M Sobczak, A Jozkowicz, J Dulak |
Mediators of Inflammation | 2016 |
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Overexpression of Latent TGFβ Binding Protein 4 in Muscle Ameliorates Muscular Dystrophy through Myostatin and TGFβ
KM Lamar, S Bogdanovich, BB Gardner, QQ Gao, T Miller, JU Earley, M Hadhazy, AH Vo, L Wren, JD Molkentin, EM McNally, GA Cox |
PLoS genetics | 2016 |
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Developmental signalling pathways in renal fibrosis: the roles of Notch, Wnt and Hedgehog
M Edeling, G Ragi, S Huang, H Pavenstädt, K Susztak |
Nature Reviews Nephrology | 2016 |
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AMPK Activation by Metformin Suppresses Abnormal Extracellular Matrix Remodeling in Adipose Tissue and Ameliorates Insulin Resistance in Obesity
T Luo, A Nocon, J Fry, A Sherban, X Rui, B Jiang, XJ Xu, J Han, Y Yan, Q Yang, Q Li, M Zang |
Diabetes | 2016 |
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Role of redoximiRs in fibrogenesis
M Fierro-Fernández, V Miguel, S Lamas |
Redox Biology | 2016 |
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Downregulation of TGF-β Receptor-2 Expression and Signaling through Inhibition of Na/K-ATPase
J La, E Reed, L Chan, LV Smolyaninova, OA Akomova, GM Mutlu, SN Orlov, NO Dulin, D Gullberg |
PloS one | 2016 |
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Does bariatric surgery improve adipose tissue function?: Bariatric surgery and adipose tissue
H Frikke-Schmidt, RW O'Rourke, CN Lumeng, DA Sandoval, RJ Seeley |
Obesity Reviews | 2016 |
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Profibrotic up-regulation of glucose transporter 1 by TGF- involves activation of MEK and mammalian target of rapamycin complex 2 pathways
M Andrianifahanana, DM Hernandez, X Yin, JH Kang, MY Jung, Y Wang, ES Yi, AC Roden, AH Limper, EB Leof |
The FASEB Journal | 2016 |
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Links between coagulation, inflammation, regeneration, and fibrosis in kidney pathology
B Suárez-Álvarez, H Liapis, HJ Anders |
Laboratory Investigation | 2016 |
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Macrophages in Tissue Repair, Regeneration, and Fibrosis
TA Wynn, KM Vannella |
Immunity | 2016 |
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Comparison of transforming growth factor beta expression in healthy and diseased human tendon
HC Goodier, AJ Carr, SJ Snelling, L Roche, K Wheway, B Watkins, SG Dakin |
Arthritis Research & Therapy | 2016 |
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Adverse outcome pathway development from protein alkylation to liver fibrosis
T Horvat, B Landesmann, A Lostia, M Vinken, S Munn, M Whelan |
Archives of Toxicology | 2016 |
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HIV and HCV Co-Culture Promotes Profibrogenic Gene Expression through an Epimorphin-Mediated ERK Signaling Pathway in Hepatic Stellate Cells
L Shi, E Qin, J Zhou, J Zhao, W Nie, T Jiang, W Chen, D Wu, L Huang, L Liu, L Lv, M Zhao, Z Zhang, F Wang, G Waris |
PloS one | 2016 |
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Connexins, Pannexins, and Their Channels in Fibroproliferative Diseases
B Cogliati, G Mennecier, J Willebrords, TC da Silva, M Maes, IV Pereira, SC Yanguas, FJ Hernandez-Blazquez, ML Dagli, M Vinken |
The Journal of Membrane Biology | 2016 |
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Inhibitors of Arg-Gly-Asp-Binding Integrins Reduce Development of Pancreatic Fibrosis in Mice
B Ulmasov, BA Neuschwander-Tetri, J Lai, V Monastyrskiy, T Bhat, MP Yates, J Oliva, MJ Prinsen, PG Ruminski, DW Griggs |
CMGH Cellular and Molecular Gastroenterology and Hepatology | 2016 |
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Endothelial to Mesenchymal Transition (EndoMT) in the Pathogenesis of Human Fibrotic Diseases
S Piera-Velazquez, F Mendoza, S Jimenez |
Journal of Clinical Medicine | 2016 |
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Targeting collagen for diagnostic imaging and therapeutic delivery
H Wahyudi, AA Reynolds, Y Li, SC Owen, SM Yu |
Journal of Controlled Release | 2016 |
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Endoplasmic reticulum stress in bone marrow-derived cells prevents acute cardiac inflammation and injury in response to angiotensin II
TT Li, LX Jia, WM Zhang, XY Li, J Zhang, YL Li, HH Li, YF Qi, J Du |
Cell Death and Disease | 2016 |
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Mimicking the Kidney: A Key Role in Organ-on-Chip Development
R Paoli, J Samitier |
MICROMACHINES-BASEL | 2016 |
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Metformin Reduces Bleomycin-induced Pulmonary Fibrosis in Mice
SM Choi, AH Jang, H Kim, KH Lee, YW Kim |
Journal of Korean Medical Science | 2016 |
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Isoform-Specific Modulation of Inflammation Induced by Adenoviral Mediated Delivery of Platelet-Derived Growth Factors in the Adult Mouse Heart
R Gallini, J Huusko, S Ylä-Herttuala, C Betsholtz, J Andrae, MJ Goumans |
PloS one | 2016 |
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Heparanase: A Potential New Factor Involved in the Renal Epithelial Mesenchymal Transition (EMT) Induced by Ischemia/Reperfusion (I/R) Injury
V Masola, G Zaza, G Gambaro, M Onisto, G Bellin, G Vischini, I Khamaysi, A Hassan, S Hamoud, O Nativ, SN Heyman, A Lupo, I Vlodavsky, Z Abassi, G Camussi |
PloS one | 2016 |
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Procollagen C-Proteinase Enhancer 1 (PCPE-1) as a Plasma Marker of Muscle and Liver Fibrosis in Mice
E Hassoun, M Safrin, H Ziv, S Pri-Chen, E Kessler, MA Avila |
PloS one | 2016 |
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Pivotal Role of Carbohydrate Sulfotransferase 15 in Fibrosis and Mucosal Healing in Mouse Colitis
K Suzuki, S Arumugam, J Yokoyama, Y Kawauchi, Y Honda, H Sato, Y Aoyagi, S Terai, K Okazaki, Y Suzuki, S Mizumoto, K Sugahara, R Atreya, MF Neurath, K Watanabe, T Hashiguchi, H Yoneyama, H Asakura, B Siegmund |
PloS one | 2016 |
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Keratinocyte Induced Differentiation of Mesenchymal Stem Cells into Dermal Myofibroblasts: A Role in EffectiveWound Healing
PJ Mishra, PJ Mishra, D Banerjee |
International Journal of Translational Science | 2016 |
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Soy-based renoprotection
NJ McGraw, ES Krul, E Grunz-Borgmann, AR Parrish |
World Journal of Nephrology | 2016 |
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miR-130b-3p Modulates Epithelial-Mesenchymal Crosstalk in Lung Fibrosis by Targeting IGF-1
S Li, J Geng, X Xu, X Huang, D Leng, D Jiang, J Liang, C Wang, D Jiang, H Dai, Q Ding |
PloS one | 2016 |
|
Genotype-Specific Interaction of Latent TGFβ Binding Protein 4 with TGFβ
KM Lamar, T Miller, L Dellefave-Castillo, EM McNally, NH Bishopric |
PloS one | 2016 |
|
Matrix-driven Myosin II Mediates the Pro-fibrotic Fibroblast Phenotype
BD Southern, LM Grove, SO Rahaman, S Abraham, RG Scheraga, KA Niese, H Sun, EL Herzog, F Liu, DJ Tschumperlin, TT Egelhoff, SS Rosenfeld, MA Olman |
The Journal of biological chemistry | 2016 |
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Polidocanol induced tubal occlusion in nonhuman primates: immunohistochemical detection of collagen I-V
OD Slayden, DO Lee, S Yao, JT Jensen |
Contraception | 2016 |
|
Anti-Vascular Endothelial Growth Factor (Bevacizumab) Therapy Reduces Hypertrophic Scar Formation in a Rabbit Ear Wounding Model
DH Kwak, TH Bae, WS Kim, HK Kim |
Archives of Plastic Surgery | 2016 |
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Microbial Translocation Associated with an Acute-Phase Response and Elevations in MMP-1, HO-1, and Proinflammatory Cytokines in Strongyloides stercoralis Infection
A Rajamanickam, S Munisankar, Y Bhootra, C Dolla, TB Nutman, S Babu, JA Appleton |
Infection and immunity | 2016 |
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ROCK Inhibition Promotes Attachment, Proliferation, and Wound Closure in Human Embryonic Stem Cell–Derived Retinal Pigmented Epithelium
RH Croze, WJ Thi, DO Clegg |
Translational Vision Science & Technology | 2016 |
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Interleukin-10–mediated regenerative postnatal tissue repair is dependent on regulation of hyaluronan metabolism via fibroblast-specific STAT3 signaling
S Balaji, X Wang, A King, LD Le, SS Bhattacharya, CM Moles, MJ Butte, VA de Perez, KW Liechty, TN Wight, TM Crombleholme, PL Bollyky, SG Keswani |
The FASEB Journal | 2016 |
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Global gene profiling of aging lungs in Atp8b1 mutant mice
R Soundararajan, T Stearns, A Czachor, J Fukumoto, C Turn, E Westermann-Clark, M Breitzig, L Tan, R Lockey, B King, N Kolliputi |
Aging | 2016 |
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Interferon gamma peptidomimetic targeted to interstitial myofibroblasts attenuates renal fibrosis after unilateral ureteral obstruction in mice
F Poosti, R Bansal, S Yazdani, J Prakash, L Beljaars, J Born, MH de Borst, H Goor, JL Hillebrands, K Poelstra |
Oncotarget | 2016 |
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Effect of Oral ω3-Polyunsaturated Fatty Acids as a Complement Management to Control Fistula Output and Inflammation in Patients With Digestive Fistula.
Martínez-Ordaz JL, Boscó-Gárate I, Cérbulo-Vázquez A, Arriaga-Pizano L, Wong-Baeza I, Sánchez-Fernandez P, López-Macías C, Isibasi A, Ferat-Osorio E |
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract | 2016 |
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2-Deoxy glucose regulate MMP-9 in a SIRT-1 dependent and NFkB independent mechanism.
Edatt L, Haritha K, Sruthi TV, Aswini P, Sameer Kumar VB |
Molecular and Cellular Biochemistry | 2016 |
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Regulatory mechanisms of anthrax toxin receptor 1-dependent vascular and connective tissue homeostasis
TY Besschetnova, T Ichimura, N Katebi, BS Croix, JV Bonventre, BR Olsen |
Matrix Biology | 2015 |
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The significance of macrophage polarization subtypes for animal models of tissue fibrosis and human fibrotic diseases
PJ Wermuth, SA Jimenez |
Clinical and Translational Medicine | 2015 |
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MiR-125b is Critical for Fibroblast-to-Myofibroblast Transition and Cardiac Fibrosis
V Nagpal, R Rai, AT Place, SB Murphy, SK Verma, AK Ghosh, DE Vaughan |
Circulation | 2015 |
|
Interleukin-1 Family Cytokines in Liver Diseases
H Tsutsui, X Cai, S Hayashi |
Mediators of Inflammation | 2015 |
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Antagonism of toll-like receptor 2 attenuates the formation and progression of abdominal aortic aneurysm
H Yan, B Cui, X Zhang, X Fu, J Yan, X Wang, X Lv, Z Chen, Z Hu |
Acta Pharmaceutica Sinica B | 2015 |
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Regulation of myofibroblast differentiation by miR-424 during epithelial-to-mesenchymal transition
X Xiao, C Huang, C Zhao, X Gou, LK Senavirathna, M Hinsdale, P Lloyd, L Liu |
Archives of Biochemistry and Biophysics | 2015 |
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Activation of AMP-Activated Protein Kinase Prevents TGF-β1–Induced Epithelial-Mesenchymal Transition and Myofibroblast Activation
S Thakur, S Viswanadhapalli, JB Kopp, Q Shi, JL Barnes, K Block, Y Gorin, HE Abboud |
The American Journal of Pathology | 2015 |
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P311 promotes renal fibrosis via TGFβ1/Smad signaling
Z Yao, S Yang, W He, L Li, R Xu, X Zhang, H Li, R Zhan, W Sun, J Tan, J Zhou, G Luo, J Wu |
Scientific Reports | 2015 |
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EPA, not DHA, prevents fibrosis in pressure overload-induced heart failure: potential role of free fatty acid receptor 4
JA Eclov, Q Qian, R Redetzke, Q Chen, SC Wu, CL Healy, SB Ortmeier, E Harmon, GC Shearer, TD OConnell |
Journal of lipid research | 2015 |
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CYP epoxygenase 2J2 prevents cardiac fibrosis by suppression of transmission of pro-inflammation from cardiomyocytes to macrophages
L Yang, L Ni, Q Duan, X Wang, C Chen, S Chen, S Chaugai, DC Zeldin, JR Tang, DW Wang |
Prostaglandins & Other Lipid Mediators | 2015 |
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Molecular mechanisms of subretinal fibrosis in age-related macular degeneration
K Ishikawa, R Kannan, DR Hinton |
Experimental Eye Research | 2015 |
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Increased Expression of Connective Tissue Growth Factor (CTGF) in Multiple Organs After Exposure of Non-Human Primates (NHP) to Lethal Doses of Radiation:
P Zhang, W Cui, KG Hankey, AM Gibbs, CP Smith, C Taylor-Howell, SR Kearney, TJ MacVittie |
Health Physics | 2015 |
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Cannabinoid receptor 1 is a major mediator of renal fibrosis
L Lecru, C Desterke, S Grassin-Delyle, C Chatziantoniou, S Vandermeersch, A Devocelle, A Vernochet, N Ivanovski, C Ledent, S Ferlicot, M Dalia, M Saïd, S Beaudreuil, B Charpentier, A Vazquez, J Giron-Michel, B Azzarone, A Durrbach, H François |
Kidney International | 2015 |
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Myocardin-related Transcription Factor Regulates Nox4 Protein Expression: LINKING CYTOSKELETAL ORGANIZATION TO REDOX STATE
M Rozycki, JF Bialik, P Speight, Q Dan, TE Knudsen, SG Szeto, DA Yuen, K Szászi, SF Pedersen, A Kapus |
The Journal of biological chemistry | 2015 |
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Absence of nicotinic acetylcholine receptor 7 subunit amplifies inflammation and accelerates onset of fibrosis: an inflammatory kidney model
LD Truong, J Trostel, GE Garcia |
The FASEB Journal | 2015 |
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Regulation of inflammation and fibrosis by macrophages in lymphedema
S Ghanta, DA Cuzzone, JS Torrisi, NJ Albano, WJ Joseph, IL Savetsky, JC Gardenier, D Chang, JC Zampell, BJ Mehrara |
American journal of physiology. Heart and circulatory physiology | 2015 |
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Novel insights into the function and dynamics of extracellular matrix in liver fibrosis
MA Karsdal, T Manon-Jensen, F Genovese, JH Kristensen, MJ Nielsen, JM Sand, NU Hansen, AC Bay-Jensen, CL Bager, A Krag, A Blanchard, H Krarup, DJ Leeming, D Schuppan |
AJP Gastrointestinal and Liver Physiology | 2015 |
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Fibrosis Related Inflammatory Mediators: Role of the IL-10 Cytokine Family
E Sziksz, D Pap, R Lippai, NJ Béres, A Fekete, AJ Szabó, Á Vannay |
Mediators of Inflammation | 2015 |
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Pathological aspects of bovine focal fibrogranulomatous proliferative panniculitis (Lechiguana)
GB Andrade, HM Herrera, WT Barreto, SL Ladeira, EM Mota, LG Caputo, HL Lenzi |
Veterinary Research Communications | 2015 |
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Staging of liver fibrosis or cirrhosis: The role of hepatic venous pressure gradient measurement
KT Suk |
World journal of hepatology | 2015 |
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Osteopontin is indispensible for AP1-mediated angiotensin II-related miR-21 transcription during cardiac fibrosis
JM Lorenzen, C Schauerte, A Hubner, M Kolling, F Martino, K Scherf, S Batkai, K Zimmer, A Foinquinos, T Kaucsar, J Fiedler, R Kumarswamy, C Bang, D Hartmann, SK Gupta, J Kielstein, A Jungmann, HA Katus, F Weidemann, OJ Muller, H Haller, T Thum |
European Heart Journal | 2015 |
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Hydrogen Sulfide as a Potential Therapeutic Target in Fibrosis
S Zhang, C Pan, F Zhou, Z Yuan, H Wang, W Cui, G Zhang |
Oxidative medicine and cellular longevity | 2015 |
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Matrix Metalloproteinase Mediated Type I Collagen Degradation — An Independent Risk Factor for Mortality in Women
K Dragsbæk, JS Neergaard, HB Hansen, I Byrjalsen, P Alexandersen, SN Kehlet, AC Bay-Jensen, C Christiansen, MA Karsdal |
EBioMedicine | 2015 |
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Airway Remodeling in Chronic Obstructive Pulmonary Disease and Asthma: the Role of Matrix Metalloproteinase-9
K Grzela, M Litwiniuk, W Zagorska, T Grzela |
Archivum Immunologiae et Therapiae Experimentalis | 2015 |
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Management of Systemic-Sclerosis-Associated Interstitial Lung Disease
KC Silver, RM Silver |
Rheumatic Disease Clinics of North America | 2015 |
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Sulodexide alone or in combination with low doses of everolimus inhibits the hypoxia-mediated epithelial to mesenchymal transition in human renal proximal tubular cells
G Zaza, V Masola, S Granata, G Bellin, AD Gassa, M Onisto, G Gambaro, A Lupo |
Journal of Nephrology | 2015 |
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Cachexia-associated adipose tissue morphological rearrangement in gastrointestinal cancer patients: Adipose tissue remodelling and cachexia
ML Batista, FS Henriques, RX Neves, MR Olivan, EM Matos-Neto, PS Alcântara, LF Maximiano, JP Otoch, MJ Alves, M Seelaender |
Journal of Cachexia, Sarcopenia and Muscle | 2015 |
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Response of endothelial cells and pericytes to hypoxia and erythropoietin in a co-culture assay dedicated to soft tissue repair
G Schneider, M Bubel, T Pohlemann, M Oberringer |
Molecular and Cellular Biochemistry | 2015 |
|
Update on biomarkers in systemic sclerosis: tools for diagnosis and treatment
AJ Affandi, TR Radstake, W Marut |
Seminars in Immunopathology | 2015 |
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Rhein: A Review of Pharmacological Activities
YX Zhou, W Xia, W Yue, C Peng, K Rahman, H Zhang |
Evidence-Based Complementary and Alternative Medicine | 2015 |
|
Human xylosyltransferases – mediators of arthrofibrosis? New pathomechanistic insights into arthrofibrotic remodeling after knee replacement therapy
I Faust, P Traut, F Nolting, J Petschallies, E Neumann, E Kunisch, J Kuhn, C Knabbe, D Hendig |
Scientific Reports | 2015 |
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Omental adipose tissue fibrosis and insulin resistance in severe obesity
V Guglielmi, M Cardellini, F Cinti, F Corgosinho, I Cardolini, M D'Adamo, MC Zingaretti, A Bellia, D Lauro, P Gentileschi, M Federici, S Cinti, P Sbraccia |
Nutrition and Diabetes | 2015 |
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Impact of AMP-Activated Protein Kinase α1 Deficiency on Tissue Injury following Unilateral Ureteral Obstruction
S Mia, G Federico, M Feger, T Pakladok, A Meissner, J Voelkl, HJ Groene, I Alesutan, F Lang, L Bertrand |
PloS one | 2015 |
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Simvastatin impairs the induction of pulmonary fibrosis caused by a western style diet: a preliminary study
P Kruzliak, DL Hare, V Zvonicek, J Klimas, A Zulli |
Journal of Cellular and Molecular Medicine | 2015 |
|
Epigenetics and the overhealing wound: the role of DNA methylation in fibrosis
R Neary, CJ Watson, JA Baugh |
Fibrogenesis & Tissue Repair | 2015 |
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Leukocytes: The Double-Edged Sword in Fibrosis
Jakub Kryczka, Joanna Boncela |
Mediators of Inflammation | 2015 |
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Linking immune responses with fibrosis in allergic eye disease:
SB Dale, DR Saban |
Current Opinion in Allergy and Clinical Immunology | 2015 |
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Nodes with high centrality in protein interaction networks are responsible for driving signaling pathways in diabetic nephropathy
M Abedi, Y Gheisari |
PeerJ | 2015 |
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MicroRNAs as potential targets for progressive pulmonary fibrosis
S Rajasekaran, P Rajaguru, PS Gandhi |
Frontiers in pharmacology | 2015 |
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Co-localization of LTBP-2 with FGF-2 in fibrotic human keloid and hypertrophic scar
MA Sideek, A Teia, Z Kopecki, AJ Cowin, MA Gibson |
Journal Of Molecular Histology | 2015 |
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Geranylgeranylacetone attenuates hepatic fibrosis by increasing the expression of heat shock protein 70
W He, Y Zhuang, L Wang, L Qi, B Chen, M Wang, D Shao, J Chen |
Molecular medicine reports | 2015 |
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Balanced regulation of the CCN family of matricellular proteins: a novel approach to the prevention and treatment of fibrosis and cancer
BL Riser, JL Barnes, J Varani |
Journal of Cell Communication and Signaling | 2015 |
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Mucosal inflammation at the respiratory interface: a zebrafish model
F Progatzky, HT Cook, JR Lamb, L Bugeon, MJ Dallman |
American journal of physiology. Lung cellular and molecular physiology | 2015 |
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The Role of Tyrosine Kinase Receptors in Peritoneal Fibrosis
L Wang, S Zhuang |
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis | 2015 |
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UEG Week 2015 Poster Presentations
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United European gastroenterology journal | 2015 |
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Increased expression of p21WAF1/CIP1 in kidney proximal tubules mediates fibrosis
J Megyesi, A Tarcsafalvi, S Li, R Hodeify, NS Seng, D Portilla, PM Price |
American journal of physiology. Renal physiology | 2014 |
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Myofiber-specific inhibition of TGF signaling protects skeletal muscle from injury and dystrophic disease in mice
F Accornero, O Kanisicak, A Tjondrokoesoemo, AC Attia, EM McNally, JD Molkentin |
Human Molecular Genetics | 2014 |
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Pharmacological and genetic depletion of fibrinogen protects from kidney fibrosis
FL Craciun, AK Ajay, D Hoffmann, J Saikumar, SL Fabian, V Bijol, BD Humphreys, VS Vaidya |
American journal of physiology. Renal physiology | 2014 |
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Regulatory T cells and immune regulation of allergic diseases: roles of IL-10 and TGF-β
O Palomares, M Martín-Fontecha, R Lauener, C Traidl-Hoffmann, O Cavkaytar, M Akdis, CA Akdis |
Genes and Immunity | 2014 |
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Modifiers of TGF-β1 effector function as novel therapeutic targets of pulmonary fibrosis
CM Lee, JW Park, WK Cho, Y Zhou, B Han, PO Yoon, J Chae, JA Elias, CG Lee |
The Korean Journal of Internal Medicine | 2014 |
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Therapeutic targets for treating fibrotic kidney diseases
SY Lee, SI Kim, ME Choi |
Translational Research | 2014 |
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Pericytes: multitasking cells in the regeneration of injured, diseased, and aged skeletal muscle
A Birbrair, T Zhang, ZM Wang, ML Messi, A Mintz, O Delbono |
Frontiers in aging neuroscience | 2014 |
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NADPH oxidase-dependent redox signaling in TGF-β-mediated fibrotic responses
F Jiang, GS Liu, GJ Dusting, EC Chan |
Redox Biology | 2014 |
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A Wnt-TGF 2 axis induces a fibrogenic program in muscle stem cells from dystrophic mice
S Biressi, EH Miyabara, SD Gopinath, PM Carlig, TA Rando |
Science Translational Medicine | 2014 |
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Autophagy Regulates TGF- Expression and Suppresses Kidney Fibrosis Induced by Unilateral Ureteral Obstruction
Y Ding, S Kim, SY Lee, JK Koo, Z Wang, ME Choi |
Journal of the American Society of Nephrology : JASN | 2014 |
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Interleukin-6 signaling drives fibrosis in unresolved inflammation
CA Fielding, GW Jones, RM McLoughlin, L McLeod, VJ Hammond, J Uceda, AS Williams, M Lambie, TL Foster, CT Liao, CM Rice, CJ Greenhill, CS Colmont, E Hams, B Coles, A Kift-Morgan, Z Newton, KJ Craig, JD Williams, GT Williams, SJ Davies, IR Humphreys, VB O'Donnell, PR Taylor, BJ Jenkins, N Topley, SA Jones |
Immunity | 2014 |
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The promotion of functional urinary bladder regeneration using anti-inflammatory nanofibers
MI Bury, NJ Fuller, JW Meisner, MD Hofer, MJ Webber, LW Chow, S Prasad, H Thaker, X Yue, VS Menon, EC Diaz, SI Stupp, EY Cheng, AK Sharma |
Biomaterials | 2014 |
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Tumor suppressor ataxia telangiectasia mutated functions downstream of TGF- 1 in orchestrating profibrotic responses
JM Overstreet, R Samarakoon, D Cardona-Grau, R Goldschmeding, PJ Higgins |
The FASEB Journal | 2014 |
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The GSK-3 Family as Therapeutic Target for Myocardial Diseases
H Lal, F Ahmad, J Woodgett, T Force |
Circulation research | 2014 |
|
Monocyte Subsets in Schistosomiasis Patients with Periportal Fibrosis
JS Fernandes, MI Araujo, DM Lopes, RP de Souza, EM Carvalho, LS Cardoso |
Mediators of Inflammation | 2014 |
|
Cardiac fibrosis as a determinant of ventricular tachyarrhythmias
N Morita, WJ Mandel, Y Kobayashi, HS Karagueuzian |
Journal of Arrhythmia | 2014 |
|
Chronic restraint stress decreases the repair potential from mesenchymal stem cells on liver injury by inhibiting TGF-β1 generation
X Yang, ZP Han, SS Zhang, PX Zhu, C Hao, TT Fan, Y Yang, L Li, YF Shi, LX Wei |
Cell Death and Disease | 2014 |
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Autophagy fosters myofibroblast differentiation through MTORC2 activation and downstream upregulation of CTGF
M Bernard, M Dieudé, B Yang, K Hamelin, K Underwood, MJ Hébert |
Autophagy | 2014 |
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Emerging role of HMGB1 in fibrotic diseases
LC Li, J Gao, J Li |
Journal of Cellular and Molecular Medicine | 2014 |
|
Amplified and selective assay of collagens by enzymatic and fluorescent reactions
H Yasmin, T Kabashima, MS Rahman, T Shibata, M Kai |
Scientific Reports | 2014 |
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Nlrp3 prevents early renal interstitial edema and vascular permeability in unilateral ureteral obstruction
WP Pulskens, LM Butter, GJ Teske, N Claessen, MC Dessing, RA Flavell, FS Sutterwala, S Florquin, JC Leemans |
PloS one | 2014 |
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Mysteries of α1-antitrypsin deficiency: emerging therapeutic strategies for a challenging disease
R Ghouse, A Chu, Y Wang, DH Perlmutter |
Disease models & mechanisms | 2014 |
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Mechanotransduction and fibrosis
D Duscher, ZN Maan, VW Wong, RC Rennert, M Januszyk, M Rodrigues, M Hu, AJ Whitmore, AJ Whittam, MT Longaker, GC Gurtner |
Journal of Biomechanics | 2014 |
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N-acetyl-seryl-aspartyl-lysyl-proline: a valuable endogenous anti-fibrotic peptide for combating kidney fibrosis in diabetes
K Kanasaki, T Nagai, K Nitta, M Kitada, D Koya |
Frontiers in pharmacology | 2014 |
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ACE2 is augmented in dystrophic skeletal muscle and plays a role in decreasing associated fibrosis
C Riquelme, MJ Acuña, J Torrejón, D Rebolledo, D Cabrera, RA Santos, E Brandan |
PloS one | 2014 |
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Mechanical offloading of incisional wounds is associated with transcriptional downregulation of inflammatory pathways in a large animal model
M Januszyk, VW Wong, KA Bhatt, IN Vial, J Paterno, MT Longaker, GC Gurtner |
Organogenesis | 2014 |
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Neuroinflammatory Mechanisms of Connective Tissue Fibrosis: Targeting Neurogenic and Mast Cell Contributions
MJ Monument, DA Hart, PT Salo, AD Befus, KA Hildebrand |
Advances in Skin & Wound Care | 2014 |
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Identification of Cadherin 11 as a Mediator of Dermal Fibrosis and Possible Role in Systemic Sclerosis: Cadherin 11 as Mediator of Dermal Fibrosis
M Wu, M Pedroza, R Lafyatis, AT George, MD Mayes, S Assassi, FK Tan, MB Brenner, SK Agarwal |
Arthritis & Rheumatology | 2014 |
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Understanding the Process of Fibrosis in Duchenne Muscular Dystrophy
Y Kharraz, J Guerra, P Pessina, AL Serrano, P Muñoz-Cánoves |
BioMed Research International | 2014 |
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Ceramide kinase is required for a normal eicosanoid response and the subsequent orderly migration of fibroblasts
DS Wijesinghe, M Brentnall, JA Mietla, LA Hoeferlin, RF Diegelmann, LH Boise, CE Chalfant |
Journal of lipid research | 2014 |
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Management of fibrosis: the mesenchymal stromal cells breakthrough
B Usunier, M Benderitter, R Tamarat, A Chapel |
Stem Cells International | 2014 |
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A novel immune competent murine hypertrophic scar contracture model: A tool to elucidate disease mechanism and develop new therapies: A novel murine hypertrophic scar contracture model
MM Ibrahim, J Bond, A Bergeron, KJ Miller, T Ehanire, C Quiles, ER Lorden, MA Medina, M Fisher, B Klitzman, MA Selim, KW Leong, H Levinson |
Wound Repair and Regeneration | 2014 |
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Homocysteine Promotes Intestinal Fibrosis in Rats with Trinitrobenzene Sulfonic Acid-Induced Colitis
H Ding, HZ Gan, WJ Fan, LY Cao, JM Xu, Q Mei |
Digestive Diseases and Sciences | 2014 |
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Clinical Relevance of Fascial Tissue and Dysfunctions
W Klingler, M Velders, K Hoppe, M Pedro, R Schleip |
Current Pain and Headache Reports | 2014 |
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Coincident Helminth Infection Modulates Systemic Inflammation and Immune Activation in Active Pulmonary Tuberculosis
PJ George, NP Kumar, R Sridhar, LE Hanna, D Nair, VV Banurekha, TB Nutman, S Babu, JM Vinetz |
PLoS neglected tropical diseases | 2014 |
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Foreign Body Response to Subcutaneous Implants in Diabetic Rats
TO Socarrás, AC Vasconcelos, PP Campos, NB Pereira, JP Souza, SP Andrade, MA Barbosa |
PloS one | 2014 |
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Interleukin-10- and Transforming Growth Factor -Independent Regulation of CD8+ T Cells Expressing Type 1 and Type 2 Cytokines in Human Lymphatic Filariasis
R Anuradha, PJ George, P Kumaran, TB Nutman, S Babu |
Clinical and vaccine immunology : CVI | 2014 |
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Space radiation-associated lung injury in a murine model
M Christofidou-Solomidou, RA Pietrofesa, E Arguiri, KS Schweitzer, EV Berdyshev, M McCarthy, A Corbitt, JS Alwood, Y Yu, RK Globus, CC Solomides, RL Ullrich, I Petrache |
American journal of physiology. Lung cellular and molecular physiology | 2014 |
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Genome-wide DNA methylation analysis in dermal fibroblasts from patients with diffuse and limited systemic sclerosis reveals common and subset-specific DNA methylation aberrancies
N Altorok, PS Tsou, P Coit, D Khanna, AH Sawalha |
Annals of the rheumatic diseases | 2014 |
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Effect of SMAD7 gene overexpression on TGF-β1-induced profibrotic responses in fibroblasts derived from Peyronie′s plaque
MJ Choi, KM Song, JM Park, MH Kwon, KD Kwon, SH Park, DS Ryu, JK Ryu, JK Suh |
Asian Journal of Andrology | 2014 |
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Profibrotic TGFβ responses require the cooperative action of PDGF and ErbB receptor tyrosine kinases
M Andrianifahanana, MC Wilkes, SK Gupta, RA Rahimi, CE Repellin, M Edens, J Wittenberger, X Yin, E Maidl, J Becker, EB Leof |
The FASEB Journal | 2013 |
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Interleukin-16 promotes cardiac fibrosis and myocardial stiffening in heart failure with preserved ejection fraction
S Tamaki, T Mano, Y Sakata, T Ohtani, Y Takeda, D Kamimura, Y Omori, Y Tsukamoto, Y Ikeya, M Kawai, A Kumanogoh, K Hagihara, R Ishii, M Higashimori, M Kaneko, H Hasuwa, T Miwa, K Yamamoto, I Komuro |
PloS one | 2013 |
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miR-199a-5p Is upregulated during fibrogenic response to tissue injury and mediates TGFbeta-induced lung fibroblast activation by targeting caveolin-1
CL Cardenas, IS Henaoui, E Courcot, C Roderburg, C Cauffiez, S Aubert, MC Copin, B Wallaert, F Glowacki, E Dewaeles, J Milosevic, J Maurizio, J Tedrow, B Marcet, JM Lo-Guidice, N Kaminski, P Barbry, T Luedde, M Perrais, B Mari, N Pottier |
PLoS genetics | 2013 |
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Diabetic nephropathy: the role of inflammation in fibroblast activation and kidney fibrosis
K Kanasaki, G Taduri, D Koya |
Frontiers in Endocrinology | 2013 |
|
Expression profiling of genes regulated by Fra-1/AP-1 transcription factor during bleomycin-induced pulmonary fibrosis
S Rajasekaran, NM Reddy, W Zhang, SP Reddy |
BMC Genomics | 2013 |
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Thrombospondin 1 Mediates High-Fat Diet-Induced Muscle Fibrosis and Insulin Resistance in Male Mice
M Inoue, Y Jiang, RH Barnes, M Tokunaga, G Martinez-Santibañez, L Geletka, CN Lumeng, DA Buchner, TH Chun |
Endocrinology | 2013 |
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Hepatic regeneration and the epithelial to mesenchymal transition
ZF Xue, XM Wu, M Liu |
World journal of gastroenterology : WJG | 2013 |
|
Dynamic Regulation of Integrin α6β4 During Angiogenesis: Potential Implications for Pathogenic Wound Healing
D Desai, P Singh, LV de Water, SE Laflamme |
Advances in Skin & Wound Care | 2013 |
|
Role of TREM1-DAP12 in Renal Inflammation during Obstructive Nephropathy
A Tammaro, I Stroo, E Rampanelli, F Blank, LM Butter, N Claessen, T Takai, M Colonna, JC Leemans, S Florquin, MC Dessing, I Armando |
PloS one | 2013 |
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Fibrosis and Adipose Tissue Dysfunction
K Sun, J Tordjman, K Clément, PE Scherer |
Cell Metabolism | 2013 |
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Fibrosis of two: Epithelial cell-fibroblast interactions in pulmonary fibrosis
N Sakai, AM Tager |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2013 |
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Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis
BS Ding, Z Cao, R Lis, DJ Nolan, P Guo, M Simons, ME Penfold, K Shido, SY Rabbany, S Rafii |
Nature | 2013 |
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Role of warm ischemia on innate and adaptive responses in a preclinical renal auto-transplanted porcine model
L Rossard, F Favreau, S Giraud, R Thuillier, SL Pape, JM Goujon, A Valagier, T Hauet |
Journal of Translational Medicine | 2013 |
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Extracellular Matrix Remodeling: The Common Denominator in Connective Tissue DiseasesPossibilities for Evaluation and Current Understanding of the Matrix as More Than a Passive Architecture, but a Key Player in Tissue Failure
MA Karsdal, MJ Nielsen, JM Sand, K Henriksen, F Genovese, AC Bay-Jensen, V Smith, JI Adamkewicz, C Christiansen, DJ Leeming |
ASSAY and Drug Development Technologies | 2013 |
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Hypoxia Induces Mesenchymal Gene Expression in Renal Tubular Epithelial Cells: An in vitro Model of Kidney Transplant Fibrosis
S Zell, R Schmitt, S Witting, HH Kreipe, K Hussein, JU Becker |
Nephron Extra | 2013 |
|
Canine visceral leishmaniasis as a systemic fibrotic disease
LC Silva, RS Castro, MM Figueiredo, MS Michalick, WL Tafuri, WL Tafuri |
International Journal of Experimental Pathology | 2013 |
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Global gene expression profiling in PAI-1 knockout murine heart and kidney: molecular basis of cardiac-selective fibrosis
AK Ghosh, SB Murphy, R Kishore, DE Vaughan |
PloS one | 2013 |
|
Role of Endothelial to Mesenchymal Transition in the Pathogenesis of the Vascular Alterations in Systemic Sclerosis
SA Jimenez |
ISRN Rheumatology | 2013 |
|
Biomechanical regulation of mesenchymal cell function:
DJ Tschumperlin, F Liu, AM Tager |
Current Opinion in Rheumatology | 2013 |
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Magnetoelastic vibrational biomaterials for real-time monitoring and modulation of the host response
E Vlaisavljevich, HR Holmes, EL Tan, Z Qian, S Trierweiler, KG Ong, RM Rajachar |
Journal of Materials Science: Materials in Medicine | 2013 |
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Role of the endothelial-to-mesenchymal transition in renal fibrosis of chronic kidney disease
J He, Y Xu, D Koya, K Kanasaki |
Clinical and Experimental Nephrology | 2013 |
|
Iron chelator alleviates tubulointerstitial fibrosis in diabetic nephropathy rats by inhibiting the expression of tenascinC and other correlation factors
C Zou, R Xie, Y Bao, X Liu, M Sui, S M, S Li, H Yin |
Endocrine | 2013 |
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TGF-β1-induced synthesis of collagen fibers in skeletal muscle-derived stem cells
Y Chen, Y Peng, Y Wang, Y Weng, T Li, Y Zhang, Z Chen |
Journal of Huazhong University of Science and Technology [Medical Sciences] | 2013 |
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Musculoskeletal regeneration and its implications for the treatment of tendinopathy
JB Sereysky, EL Flatow, N Andarawis-Puri |
International Journal of Experimental Pathology | 2013 |
|
Human erythropoietin gene delivery for cardiac remodeling of myocardial infarction in rats
Y Lee, AN McGinn, CD Olsen, K Nam, M Lee, SK Shin, SW Kim |
Journal of Controlled Release | 2013 |
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MMP mediated degradation of type IV collagen alpha 1 and alpha 3 chains reflects basement membrane remodeling in experimental and clinical fibrosis--validation of two novel biomarker assays
JM Sand, L Larsen, C Hogaboam, F Martinez, M Han, MR Larsen, A Nawrocki, Q Zheng, MA Karsdal, DJ Leeming |
PloS one | 2013 |
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The CYP2E1 inhibitor DDC up-regulates MMP-1 expression in hepatic stellate cells via an ERK1/2- and Akt-dependent mechanism
T Liu, P Wang, M Cong, Y Xu, J Jia, H You |
Bioscience Reports | 2013 |
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Oxidative stress, fibrosis, and early afterdepolarization-mediated cardiac arrhythmias
HS Karagueuzian, TP Nguyen, Z Qu, JN Weiss |
Frontiers in physiology | 2013 |
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The Enigmatic Cytokine Oncostatin M and Roles in Disease
CD Richards |
ISRN Inflammation | 2013 |
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Overexpression of MMP-7 increases collagen 1A2 in the aging kidney
A Ślusarz, LN Nichols, EA Grunz-Borgmann, G Chen, AD Akintola, JM Catania, RC Burghardt, JP Trzeciakowski, AR Parrish |
Physiological Reports | 2013 |
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Cellular mechanisms of tissue fibrosis. 3. Novel mechanisms of kidney fibrosis
G Campanholle, G Ligresti, SA Gharib, JS Duffield |
American journal of physiology. Cell physiology | 2013 |
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Inhibition of platelet activation by clopidogrel prevents hypertension-induced cardiac inflammation and fibrosis
LX Jia, GM Qi, O Liu, TT Li, M Yang, W Cui, WM Zhang, YF Qi, J Du |
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy | 2013 |
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Mesenchymal cells emerge as primary contributors to fibrosis in multiple tissues
M Tsang |
Journal of Cell Communication and Signaling | 2013 |
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Canonical Transforming Growth Factor-β Signaling Regulates Disintegrin Metalloprotease Expression in Experimental Renal Fibrosis via miR-29
V Ramdas, M McBride, L Denby, AH Baker |
The American Journal of Pathology | 2013 |
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CCAAT-enhancer binding protein delta (C/EBPδ) attenuates tubular injury and tubulointerstitial fibrogenesis during chronic obstructive nephropathy
JW Duitman, KS Borensztajn, WP Pulskens, JC Leemans, S Florquin, CA Spek |
Laboratory Investigation | 2013 |
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Systems-Level Lipid Analysis Methodologies for Qualitative and Quantitative Investigation of Lipid Signaling Events During Wound Healing
DS Wijesinghe, CE Chalfant |
Advances in Skin & Wound Care | 2013 |
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The development of nasal polyp disease involves early nasal mucosal inflammation and remodelling
J Meng, P Zhou, Y Liu, F Liu, X Yi, S Liu, G Holtappels, C Bachert, N Zhang |
PloS one | 2013 |
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Bone marrow-derived stem cells ameliorate hepatic fibrosis by down-regulating interleukin-17
L Zheng, J Chu, Y Shi, X Zhou, L Tan, Q Li, L Cui, Z Han, Y Han, D Fan |
Cell & Bioscience | 2013 |
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Liver protective effect of ursodeoxycholic acid includes regulation of ADAM17 activity
H Buryova, K Chalupsky, O Zbodakova, I Kanchev, M Jirouskova, M Gregor, R Sedlacek |
BMC Gastroenterology | 2013 |
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MicroRNAs in kidney fibrosis and diabetic nephropathy: roles on EMT and EndMT
SP Srivastava, D Koya, K Kanasaki |
BioMed Research International | 2013 |
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Bevacizumab attenuates hepatic fibrosis in rats by inhibiting activation of hepatic stellate cells
Y Huang, H Feng, T Kan, B Huang, M Zhang, Y Li, C Shi, M Wu, Y Luo, J Yang, F Xu |
PloS one | 2013 |
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Willin, an upstream component of the hippo signaling pathway, orchestrates mammalian peripheral nerve fibroblasts
S Moleirinho, C Patrick, AM Tilston-Lünel, JR Higginson, L Angus, M Antkowiak, SC Barnett, MB Prystowsky, PA Reynolds, FJ Gunn-Moore |
PloS one | 2013 |
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The anti-fibrotic effect of bone morphogenic protein-7(BMP-7) on liver fibrosis
L Zhong, X Wang, S Wang, L Yang, H Gao, C Yang |
International journal of medical sciences | 2013 |
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LOX-mediated collagen crosslinking is responsible for fibrosis-enhanced metastasis
TR Cox, D Bird, AM Baker, HE Barker, MW Ho, G Lang, JT Erler |
Cancer research | 2013 |
|
Myofibroblasts in Fibrotic Kidneys
N Nakagawa, JS Duffield |
Current Pathobiology Reports | 2013 |
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Identification and comparative analyses of myocardial miRNAs involved in the fetal response to maternal obesity
A Maloyan, S Muralimanoharan, S Huffman, LA Cox, PW Nathanielsz, L Myatt, MJ Nijland |
2013 | |
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Inhibition of protein translation as a novel mechanism for prostaglandin E2 regulation of cell functions
K Okunishi, AJ DeGraaf, Z Zaslona, M Peters-Golden |
The FASEB Journal | 2013 |
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Pancreatic Islet Vasculature Adapts to Insulin Resistance Through Dilation and Not Angiogenesis
C Dai, M Brissova, RB Reinert, L Nyman, EH Liu, C Thompson, A Shostak, M Shiota, T Takahashi, AC Powers |
Diabetes | 2013 |
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Apoptosis and angiogenesis: an evolving mechanism for fibrosis
A Johnson, LA DiPietro |
The FASEB Journal | 2013 |
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Dynamic Interplay of Smooth Muscle α-Actin Gene-Regulatory Proteins Reflects the Biological Complexity of Myofibroblast Differentiation
A Strauch, S Hariharan |
Biology : open access journal | 2013 |
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Asbestos-associated mesothelial cell autoantibodies promote collagen deposition in vitro
KM Serve, B Black, J Szeinuk, JC Pfau |
Inhalation Toxicology | 2013 |
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Chinese herbal medicine Shenqi Detoxification Granule inhibits fibrosis in adenine induced chronic renal failure rats.
Peng M, Cai P, Ma H, Meng H, Xu Y, Zhang X, Si G |
African journal of traditional, complementary, and alternative medicines : AJTCAM | 2013 |
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Accelerating repaired basement membrane after bevacizumab treatment on alkali-burned mouse cornea
Lee KJ, Lee JY, Lee SH, Choi TH |
BMB Reports | 2013 |
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Increased expression of S100A8 and S100A9 in patients with diffuse cutaneous systemic sclerosis. A correlation with organ involvement and immunological abnormalities.
Xu X, Wu WY, Tu WZ, Chu HY, Zhu XX, Liang MR, Xue Y, Wang JC, Zou HJ |
Clinical Rheumatology | 2013 |
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Bromelain down-regulates myofibroblast differentiation in an in vitro wound healing assay.
Aichele K, Bubel M, Deubel G, Pohlemann T, Oberringer M |
Naunyn-Schmiedeberg's Archives of Pharmacology | 2013 |
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Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis
RJ O'Donoghue, DA Knight, CD Richards, CM Prêle, HL Lau, AG Jarnicki, J Jones, S Bozinovski, R Vlahos, S Thiem, BS McKenzie, B Wang, P Stumbles, GJ Laurent, RJ McAnulty, S Rose-John, HJ Zhu, GP Anderson, MR Ernst, SE Mutsaers |
EMBO Molecular Medicine | 2012 |
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Sprouty Is a Negative Regulator of Transforming Growth Factor β-Induced Epithelial-to-Mesenchymal Transition and Cataract
EH Shin, MA Basson, ML Robinson, JW McAvoy, FJ Lovicu |
Molecular Medicine | 2012 |
|
Gli-similar proteins: their mechanisms of action, physiological functions, and roles in disease
K Lichti-Kaiser, G ZeRuth, HS Kang, S Vasanth, AM Jetten |
Vitamins and hormones | 2012 |
|
PAI-1 in Tissue Fibrosis
AK Ghosh, DE Vaughan |
Journal of Cellular Physiology | 2012 |
|
Cytokine mediated tissue fibrosis
LA Borthwick, TA Wynn, AJ Fisher |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2012 |
|
Altered Circulating Levels of Matrix Metalloproteinases and Inhibitors Associated with Elevated Type 2 Cytokines in Lymphatic Filarial Disease
R Anuradha, JP George, N Pavankumar, V Kumaraswami, TB Nutman, S Babu |
PLoS neglected tropical diseases | 2012 |
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Cathepsin S Deficiency Results in Abnormal Accumulation of Autophagosomes in Macrophages and Enhances Ang II–Induced Cardiac Inflammation
L Pan, Y Li, L Jia, Y Qin, G Qi, J Cheng, Y Qi, H Li, J Du, G Pasterkamp |
PloS one | 2012 |
|
Cell signals influencing hepatic fibrosis
M Cong, K Iwaisako, C Jiang, T Kisseleva |
International Journal of Hepatology | 2012 |
|
Fell-Muir lecture: connective tissue growth factor (CCN2) - a pernicious and pleiotropic player in the development of kidney fibrosis
RM Mason |
International Journal of Experimental Pathology | 2012 |
|
Phenolic Secoiridoids in Extra Virgin Olive Oil Impede Fibrogenic and Oncogenic Epithelial-to-Mesenchymal Transition: Extra Virgin Olive Oil As a Source of Novel Antiaging Phytochemicals
A Vazquez-Martin, S Fernández-Arroyo, S Cufí, C Oliveras-Ferraros, J Lozano-Sánchez, L Vellón, V Micol, J Joven, A Segura-Carretero, JA Menendez |
Rejuvenation Research | 2012 |
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Regulation of wound healing and organ fibrosis by toll-like receptors
P Huebener, RF Schwabe |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2012 |
|
Stromal fibroblast-bone marrow-derived cell interactions: implications for myofibroblast development in the cornea
V Singh, V Agrawal, MR Santhiago, SE Wilson |
Experimental Eye Research | 2012 |
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TGFbeta Family Members Are Key Mediators in the Induction of Myofibroblast Phenotype of Human Adipose Tissue Progenitor Cells by Macrophages
V Bourlier, C Sengenès, A Zakaroff-Girard, P Decaunes, B Wdziekonski, J Galitzky, P Villageois, D Esteve, P Chiotasso, C Dani, A Bouloumié, M Pesce |
PloS one | 2012 |
|
Resident mesenchymal cells and fibrosis
N Hutchison, C Fligny, JS Duffield |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2012 |
|
Hepatic macrophage migration and differentiation critical for liver fibrosis is mediated by the chemokine receptor C-C motif chemokine receptor 8 in mice
F Heymann, L Hammerich, D Storch, M Bartneck, S Huss, V Rüsseler, N Gassler, SA Lira, T Luedde, C Trautwein, F Tacke |
Hepatology | 2012 |
|
Cellular and molecular mechanisms of intestinal fibrosis
S Speca, I Giusti, F Rieder, G Latella |
World journal of gastroenterology : WJG | 2012 |
|
Osteopontin in Systemic Sclerosis and Its Role in Dermal Fibrosis
M Wu, DJ Schneider, MD Mayes, S Assassi, FC Arnett, FK Tan, MR Blackburn, SK Agarwal |
Journal of Investigative Dermatology | 2012 |
|
Inhibition of focal adhesion kinase prevents experimental lung fibrosis and myofibroblast formation
D Lagares, O Busnadiego, RA García-Fernández, M Kapoor, S Liu, DE Carter, D Abraham, X Shi-Wen, P Carreira, BA Fontaine, BS Shea, AM Tager, A Leask, S Lamas, F Rodríguez-Pascual |
Arthritis & Rheumatism | 2012 |
|
A Peptide Derived from Endostatin Ameliorates Organ Fibrosis
Y Yamaguchi, T Takihara, RA Chambers, KL Veraldi, AT Larregina, CA Feghali-Bostwick |
Science Translational Medicine | 2012 |
|
Acid sphingomyelinase deficiency contributes to resistance of scleroderma fibroblasts to Fas-mediated apoptosis
GH Samuel, S Lenna, AM Bujor, R Lafyatis, M Trojanowska |
Journal of Dermatological Science | 2012 |
|
Biological approaches to improve skeletal muscle healing after injury and disease
B Gharaibeh, Y Chun-Lansinger, T Hagen, SJ Ingham, V Wright, F Fu, J Huard |
Birth Defects Research Part C Embryo Today Reviews | 2012 |
|
TGF-β Signaling via TAK1 Pathway: Role in Kidney Fibrosis
ME Choi, Y Ding, SI Kim |
Seminars in Nephrology | 2012 |
|
Role of MicroRNAs in Fibrosis
S Vettori, S Gay, O Distler |
The open rheumatology journal | 2012 |
|
Withaferin-A Reduces Type I Collagen Expression In Vitro and Inhibits Development of Myocardial Fibrosis In Vivo
AA Challa, M Vukmirovic, J Blackmon, B Stefanovic |
PloS one | 2012 |
|
Molecular Serum Markers of Liver Fibrosis
T Liu, X Wang, MA Karsdal, DJ Leeming, F Genovese |
Biomarker insights | 2012 |
|
Immunophenotypic Alterations in Resident Immune Cells and Myocardial Fibrosis in the Aging Rhesus Macaque (Macaca mulatta) Heart
SC Macri, CC Bailey, NM de Oca, NA Silva, DL Rosene, KG Mansfield, AD Miller |
Toxicologic pathology | 2012 |
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Reciprocal Interaction between Macrophages and T cells Stimulates IFN-γ and MCP-1 Production in Ang II-induced Cardiac Inflammation and Fibrosis
Y Han, Y Li, L Jia, J Cheng, Y Qi, H Zhang, J Du |
PloS one | 2012 |
|
In vitro analyses of the anti-fibrotic effect of SPARC silencing in human Tenon’s fibroblasts: comparisons with mitomycin C
LF Seet, R Su, LZ Toh, TT Wong |
Journal of Cellular and Molecular Medicine | 2012 |
|
Structural basis of fibrillar collagen trimerization and related genetic disorders
JM Bourhis, N Mariano, Y Zhao, K Harlos, JY Exposito, EY Jones, C Moali, N Aghajari, DJ Hulmes |
Nature Structural & Molecular Biology | 2012 |
|
TGF-β-activated kinase-1: New insights into the mechanism of TGF-β signaling and kidney disease
SI Kim, ME Choi |
Kidney Research and Clinical Practice | 2012 |
|
Autophagy and mesenchymal cell fibrogenesis
M Hilscher, V Hernandez-Gea, SL Friedman |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2012 |
|
Gene-modified Mesenchymal Stem Cells Protect Against Radiation-induced Lung Injury
J Xue, X Li, Y Lu, L Gan, L Zhou, Y Wang, J Lan, S Liu, L Sun, L Jia, X Mo, J Li |
Molecular Therapy | 2012 |
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Time-course microarrays reveal early activation of the immune transcriptome and adipokine dysregulation leads to fibrosis in visceral adipose depots during diet-induced obesity
EY Kwon, SK Shin, YY Cho, UJ Jung, E Kim, T Park, JH Park, JW Yun, RA McGregor, YB Park, MS Choi |
BMC Genomics | 2012 |
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Fabrication of Biocompatible, Vibrational Magnetoelastic Materials for Controlling Cellular Adhesion
HR Holmes, EL Tan, KG Ong, RM Rajachar |
Biosensors | 2012 |
|
Fibrosis in the kidney: is a problem shared a problem halved?
TD Hewitson |
Fibrogenesis & Tissue Repair | 2012 |
|
Hepatoprotective effect of MMP-19 deficiency in a mouse model of chronic liver fibrosis
M Jirouskova, O Zbodakova, M Gregor, K Chalupsky, L Sarnova, M Hajduch, J Ehrmann, M Jirkovska, R Sedlacek |
PloS one | 2012 |
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Cell-free derivatives from mesenchymal stem cells are effective in wound therapy
PJ Mishra, PJ Mishra, D Banerjee |
World journal of stem cells | 2012 |
|
Urinary biomarkers in obstructive nephropathy
P Trnka, L Ivanova, MJ Hiatt, DG Matsell |
Clinical journal of the American Society of Nephrology : CJASN | 2012 |
|
Immunopathogenesis of lymphatic filarial disease1
S Babu, TB Nutman |
Seminars in Immunopathology | 2012 |
|
General mechanisms of nicotine-induced fibrogenesis
K Jensen, D Nizamutdinov, M Guerrier, S Afroze, D Dostal, S Glaser |
The FASEB Journal | 2012 |
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The role played by perivascular cells in kidney interstitial injury
Rojas A, Chang FC, Lin SL, Duffield JS |
Clinical nephrology | 2012 |
|
The elusive source of myofibroblasts: problem solved?
Duffield JS |
Nature Medicine | 2012 |
|
Epithelial transglutaminase 2 is needed for T cell interleukin-17 production and subsequent pulmonary inflammation and fibrosis in bleomycin-treated mice
K Oh, HB Park, OJ Byoun, DM Shin, EM Jeong, YW Kim, YS Kim, G Melino, IG Kim, DS Lee |
Journal of Experimental Medicine | 2011 |
|
Cadherin-11 contributes to pulmonary fibrosis: potential role in TGF-β production and epithelial to mesenchymal transition
DJ Schneider, M Wu, TT Le, SH Cho, MB Brenner, MR Blackburn, SK Agarwal |
The FASEB Journal | 2011 |
|
Green Tea Epigallo-Catechin-Galleate Ameliorates the Development of Obliterative Airway Disease
OD Liang, BE Kleibrink, K Schuette-Nuetgen, UU Khatwa, B Mfarrej, M Subramaniam |
Experimental Lung Research | 2011 |
|
Integrating mechanisms of pulmonary fibrosis
TA Wynn |
Journal of Experimental Medicine | 2011 |
|
Deconstructing fibrosis research: do pro-fibrotic signals point the way for chronic dermal wound regeneration?
CG Elliott, DW Hamilton |
Journal of Cell Communication and Signaling | 2011 |
|
Unraveling the biological functions of Smad7 with mouse models
L Zhu, S Chen, Y Chen |
Cell & Bioscience | 2011 |
|
Cellular and molecular mechanisms of renal fibrosis
Y Liu |
Nature Reviews Nephrology | 2011 |
|
The origin of interstitial myofibroblasts in chronic kidney disease
I Grgic, JS Duffield, BD Humphreys |
Pediatric Nephrology | 2011 |
|
The role of cell plasticity in progression and reversal of renal fibrosis
JC Dussaule, D Guerrot, AC Huby, C Chadjichristos, N Shweke, JJ Boffa, C Chatziantoniou |
International Journal of Experimental Pathology | 2011 |
|
The extracellular matrix: an active or passive player in fibrosis?
TN Wight, S Potter-Perigo |
American journal of physiology. Gastrointestinal and liver physiology | 2011 |
|
Recent Advances in Mechanisms and Treatments of Airway Remodeling in Asthma: A Message from the Bench Side to the Clinic
JY Cho |
The Korean Journal of Internal Medicine | 2011 |
|
Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer
TR Cox, JT Erler |
Disease models & mechanisms | 2011 |
|
The pivotal role of fibrocytes and mast cells in mediating fibrotic reactions to biomaterials
PT Thevenot, DW Baker, H Weng, MW Sun, L Tang |
Biomaterials | 2011 |
|
Tissue Inhibitor of Matrix-Metalloprotease–1 Predicts Risk of Hepatic Fibrosis in Human Schistosoma japonicum Infection
V Fabre, H Wu, S PondTor, H Coutinho, L Acosta, M Jiz, R Olveda, L Cheng, ES White, B Jarilla, ST McGarvey, JF Friedman, JD Kurtis |
The Journal of Infectious Diseases | 2011 |
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Deconstructing the mechanisms and consequences of TGF-β-induced EMT during cancer progression
MK Wendt, M Tian, WP Schiemann |
Cell and Tissue Research | 2011 |
|
Surgical Approaches to Create Murine Models of Human Wound Healing
VW Wong, M Sorkin, JP Glotzbach, MT Longaker, GC Gurtner |
Journal of Biomedicine and Biotechnology | 2011 |
|
The Ayurvedic medicine Salacia oblonga attenuates diabetic renal fibrosis in rats: suppression of angiotensin II/AT1 signaling
L He, Y Qi, X Rong, J Jiang, Q Yang, J Yamahara, M Murray, Y Li |
Evidence-based complementary and alternative medicine : eCAM | 2011 |
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ALMS1-deficient fibroblasts over-express extra-cellular matrix components, display cell cycle delay and are resistant to apoptosis
E Zulato, F Favaretto, C Veronese, S Campanaro, JD Marshall, S Romano, A Cabrelle, GB Collin, B Zavan, AS Belloni, E Rampazzo, JK Naggert, G Abatangelo, N Sicolo, P Maffei, G Milan, R Vettor |
PloS one | 2011 |
|
What is important to target fibrosis: location, location, location! of cold-shock proteins
M Pabst, PR Mertens |
International Urology and Nephrology | 2011 |
|
Phenytoin-Induced Gingival Overgrowth: A Review of the Molecular, Immune, and Inflammatory Features
JD Corrêa, CM Queiroz-Junior, JE Costa, AL Teixeira, TA Silva |
ISRN Dentistry | 2011 |
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Focal adhesion kinase links mechanical force to skin fibrosis via inflammatory signaling
VW Wong, KC Rustad, S Akaishi, M Sorkin, JP Glotzbach, M Januszyk, ER Nelson, K Levi, J Paterno, IN Vial, AA Kuang, MT Longaker, GC Gurtner |
Nature Medicine | 2011 |
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Participation of miR-200 in Pulmonary Fibrosis
S Yang, S Banerjee, A Freitas, YY Sanders, Q Ding, S Matalon, VJ Thannickal, E Abraham, G Liu |
The American Journal of Pathology | 2011 |
|
Themes in fibrosis and gastrointestinal inflammation
C Fiocchi, PK Lund |
AJP Gastrointestinal and Liver Physiology | 2011 |
|
Opisthorchiasis and Opisthorchis-associated cholangiocarcinoma in Thailand and Laos
B Sripa, JM Bethony, P Sithithaworn, S Kaewkes, E Mairiang, A Loukas, J Mulvenna, T Laha, PJ Hotez, PJ Brindley |
Acta Tropica | 2011 |
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A fibronectin-independent mechanism of collagen fibrillogenesis in adult liver remodeling
K Moriya, E Bae, K Honda, K Sakai, T Sakaguchi, I Tsujimoto, H Kamisoyama, DR Keene, T Sasaki, T Sakai |
Gastroenterology | 2011 |
|
Procollagen C-proteinase Enhancer Stimulates Procollagen Processing by Binding to the C-propeptide Region Only*
SV Goff, D Kronenberg, JM Bourhis, C Bijakowski, N Raynal, F Ruggiero, RW Farndale, W Stöcker, DJ Hulmes, C Moali |
The Journal of biological chemistry | 2011 |
|
Transglutaminase 2 and Its Role in Pulmonary Fibrosis
KC Olsen, RE Sapinoro, RM Kottmann, AA Kulkarni, SE Iismaa, GV Johnson, TH Thatcher, RP Phipps, PJ Sime |
American journal of respiratory and critical care medicine | 2011 |
|
High doses of TGF-β potently suppress type I collagen via the transcription factor CUX1
M Fragiadaki, T Ikeda, A Witherden, RM Mason, D Abraham, G Bou-Gharios, A Yap |
Molecular biology of the cell | 2011 |
|
Mithramycin reduces expression of fibro‐proliferative mRNAs in human gingival fibroblasts
Fajardo OA, Thompson K, Parapuram SK, Liu S, Leask A |
Cell Proliferation | 2011 |
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Starting the scar: a primary role for pericytes?
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Nature Medicine | 2011 |
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Loss of Negative Feedback Control of Nuclear Factor-κB2 Activity in Lymphocytes Leads to Fatal Lung Inflammation
L Yang, H Cui, Z Wang, B Zhang, J Ding, L Liu, HF Ding |
The American Journal of Pathology | 2010 |
|
Culture-modified bone marrow cells attenuate cardiac and renal injury in a chronic kidney disease rat model via a novel antifibrotic mechanism
DA Yuen, KA Connelly, A Advani, C Liao, MA Kuliszewski, J Trogadis, K Thai, SL Advani, Y Zhang, DJ Kelly, H Leong-Poi, A Keating, PA Marsden, DJ Stewart, RE Gilbert |
PloS one | 2010 |
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Temporal expression of chemokines dictates the hepatic inflammatory infiltrate in a murine model of schistosomiasis
ML Burke, DP McManus, GA Ramm, M Duke, Y Li, MK Jones, GN Gobert |
PLoS neglected tropical diseases | 2010 |
|
Macrophages: master regulators of inflammation and fibrosis
TA Wynn, L Barron |
Seminars in liver disease | 2010 |
|
Matrix Metalloproteinase 12-Deficiency Augments Extracellular Matrix Degrading Metalloproteinases and Attenuates IL-13–Dependent Fibrosis
SK Madala, JT Pesce, TR Ramalingam, MS Wilson, S Minnicozzi, AW Cheever, RW Thompson, MM Mentink-Kane, TA Wynn |
Journal of immunology (Baltimore, Md. : 1950) | 2010 |
|
Elastin Haploinsufficiency Results in Progressive Aortic Valve Malformation and Latent Valve Disease in a Mouse Model
RB Hinton, J Adelman-Brown, S Witt, VK Krishnamurthy, H Osinska, B Sakthivel, JF James, DY Li, DA Narmoneva, RP Mecham, DW Benson |
Circulation research | 2010 |
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Blockade of Transforming Growth Factor-β1 Accelerates Lymphatic Regeneration during Wound Repair
T Avraham, S Daluvoy, J Zampell, A Yan, YS Haviv, SG Rockson, BJ Mehrara |
The American Journal of Pathology | 2010 |
|
Targeting Fibrosis in Duchenne Muscular Dystrophy
L Zhou, H Lu |
Journal of Neuropathology and Experimental Neurology | 2010 |
|
Activation of Toll-like receptor 9 attenuates unilateral ureteral obstruction-induced renal fibrosis
B Xin, X Wang, W Jin, H Yan, B Cui, X Zhang, F Hua, H Yang, Z Hu |
Acta Pharmacologica Sinica | 2010 |
|
The pathophysiology of epithelial-mesenchymal transition induced by transforming growth factor-beta in normal and malignant mammary epithelial cells
MA Taylor, JG Parvani, WP Schiemann |
Journal of Mammary Gland Biology and Neoplasia | 2010 |
|
Inhibition of PI3K by PX-866 prevents transforming growth factor-alpha-induced pulmonary fibrosis
TD le Cras, TR Korfhagen, C Davidson, S Schmidt, M Fenchel, M Ikegami, JA Whitsett, WD Hardie |
The American Journal of Pathology | 2010 |
|
ERBB Receptor Activation Is Required for Profibrotic Responses to Transforming Growth Factor β
M Andrianifahanana, MC Wilkes, CE Repellin, M Edens, TJ Kottom, RA Rahimi, EB Leof |
Cancer research | 2010 |
|
Fibrosis under arrest
TA Wynn |
Nature Medicine | 2010 |
|
TLR4 Promotes Fibrosis but Attenuates Tubular Damage in Progressive Renal Injury
WP Pulskens, E Rampanelli, GJ Teske, LM Butter, N Claessen, IK Luirink, T van der Poll, S Florquin, JC Leemans |
Journal of the American Society of Nephrology : JASN | 2010 |
|
Hypoxia-inducible factor-1α contributes to the profibrotic action of angiotensin II in renal medullary interstitial cells
Z Wang, L Tang, Q Zhu, F Yi, F Zhang, PL Li, N Li |
Kidney International | 2010 |
|
miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis
G Liu, A Friggeri, Y Yang, J Milosevic, Q Ding, VJ Thannickal, N Kaminski, E Abraham |
Journal of Experimental Medicine | 2010 |
|
Mediators leading to fibrosis - how to measure and control them in tissue engineering
X Mu, I Bellayr, T Walters, Y Li |
Operative techniques in orthopaedics | 2010 |
|
Mast cells and hypoxia drive tissue metaplasia and heterotopic ossification in idiopathic arthrofibrosis after total knee arthroplasty
TA Freeman, J Parvizi, CJ Valle, MJ Steinbeck |
Fibrogenesis & Tissue Repair | 2010 |
|
Endoscopic treatment of Barrett's esophagus: From metaplasia to intramucosal carcinoma
J Chennat, I Waxman |
World journal of gastroenterology : WJG | 2010 |
|
SPARC deficiency results in improved surgical survival in a novel mouse model of glaucoma filtration surgery
LF Seet, R Su, VA Barathi, WS Lee, R Poh, YM Heng, E Manser, EN Vithana, T Aung, M Weaver, EH Sage, TT Wong |
PloS one | 2010 |
|
Dose-response Effects of Bleomycin on Inflammation and Pulmonary Fibrosis in Mice
SN Kim, JS Lee, HS Yang, JW Cho, SJ Kwon, YB Kim, JD Her, KH Cho, CW Song, KH Lee |
Toxicological Research | 2010 |
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Fibrosis in Human Adipose Tissue: Composition, Distribution, and Link With Lipid Metabolism and Fat Mass Loss
A Divoux, J Tordjman, D Lacasa, N Veyrie, D Hugol, A Aissat, A Basdevant, M Guerre-Millo, C Poitou, JD Zucker, P Bedossa, K Clément |
Diabetes | 2010 |
|
Regional structure-function relationships in mouse aortic valve tissue
VK Krishnamurthy, F Guilak, DA Narmoneva, RB Hinton |
Journal of Biomechanics | 2010 |
|
Gli-similar (Glis) Krüppel-like zinc finger proteins: insights into their physiological functions and critical roles in neonatal diabetes and cystic renal disease.
Kang HS, ZeRuth G, Lichti-Kaiser K, Vasanth S, Yin Z, Kim YS, Jetten AM |
Histology and histopathology | 2010 |
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Renal fibrosis is attenuated by targeted disruption of KCa3.1 potassium channels
I Grgic, E Kiss, BP Kaistha, C Busch, M Kloss, J Sautter, A Müller, A Kaistha, C Schmidt, G Raman, H Wulff, F Strutz, HJ Gröne, R Köhler, J Hoyer |
Proceedings of the National Academy of Sciences | 2009 |
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Peroxidasin is secreted and incorporated into the extracellular matrix of myofibroblasts and fibrotic kidney
Z Péterfi, A Donkó, A Orient, A Sum, A Prókai, B Molnár, Z Veréb, E Rajnavölgyi, KJ Kovács, V Müller, AJ Szabó, M Geiszt |
The American Journal of Pathology | 2009 |
|
The role of Toll-like receptor 2 in inflammation and fibrosis during progressive renal injury
JC Leemans, LM Butter, WP Pulskens, GJ Teske, N Claessen, T der Poll, S Florquin |
PloS one | 2009 |
|
Arginase-1-expressing macrophages suppress Th2 cytokine-driven inflammation and fibrosis
JT Pesce, TR Ramalingam, MM Mentink-Kane, MS Wilson, KC el Kasmi, AM Smith, RW Thompson, AW Cheever, PJ Murray, TA Wynn |
PLoS pathogens | 2009 |
|
Interferon-gamma and the interferon-inducible chemokine CXCL10 protect against aneurysm formation and rupture
VL King, AY Lin, F Kristo, TJ Anderson, N Ahluwalia, GJ Hardy, AP 3rd, DA Howatt, D Shen, AM Tager, AD Luster, A Daugherty, RE Gerszten |
Circulation | 2009 |
|
Emerging Concepts in the Pathogenesis of Lung Fibrosis
WD Hardie, SW Glasser, JS Hagood |
The American Journal of Pathology | 2009 |
|
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd |
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology | 2009 |
|
Extracellular matrix molecules: potential targets in pharmacotherapy
H Järveläinen, A Sainio, M Koulu, TN Wight, R Penttinen |
Pharmacological reviews | 2009 |
|
Protease-activated receptors and prostaglandins in inflammatory lung disease
T Peters, PJ Henry |
British Journal of Pharmacology | 2009 |
|
Transforming Growth Factor β1-mediated Activation of the Smooth Muscle α-Actin Gene in Human Pulmonary Myofibroblasts Is Inhibited by Tumor Necrosis Factor-α via Mitogen-activated Protein Kinase Kinase 1-dependent Induction of the Egr-1 Transcriptional Repressor
X Liu, RJ Kelm, AR Strauch, CH Heldin |
Molecular biology of the cell | 2009 |
|
Pulmonary fibrosis: pathogenesis, etiology and regulation
MS Wilson, TA Wynn |
Mucosal Immunology | 2009 |
|
Tissue stiffness, latent TGF-β1 Activation, and mechanical signal transduction: Implications for the pathogenesis and treatment of fibrosis
B Hinz |
Current Rheumatology Reports | 2009 |
|
Retnla (relmalpha/fizz1) suppresses helminth-induced Th2-type immunity
JT Pesce, TR Ramalingam, MS Wilson, MM Mentink-Kane, RW Thompson, AW Cheever, JF Urban, TA Wynn |
PLoS pathogens | 2009 |
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Regulation of transforming growth factor-beta-dependent cyclooxygenase-2 expression in fibroblasts
T Matsumura, T Suzuki, K Aizawa, D Sawaki, Y Munemasa, J Ishida, R Nagai |
The Journal of biological chemistry | 2009 |
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Histone deacetylase inhibition and the regulation of cell growth with particular reference to liver pathobiology
F Joanna, V Mathieu, S Sarah, D Sarah, V Karin, V Tamara, R Vera |
Journal of Cellular and Molecular Medicine | 2009 |
|
Peroxisome proliferator-activated receptor-γ abrogates Smad-dependent collagen stimulation by targeting the p300 transcriptional coactivator
AK Ghosh, S Bhattacharyya, J Wei, S Kim, Y Barak, Y Mori, J Varga |
The FASEB Journal | 2009 |
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Regulation of pathogenesis and immunity in helminth infections
RM Maizels, EJ Pearce, D Artis, M Yazdanbakhsh, TA Wynn |
Journal of Experimental Medicine | 2009 |
|
Endothelin-1 and transforming growth factor-beta1 independently induce fibroblast resistance to apoptosis via AKT activation
P Kulasekaran, CA Scavone, DS Rogers, DA Arenberg, VJ Thannickal, JC Horowitz |
American journal of respiratory cell and molecular biology | 2009 |
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Insulin-like growth factor binding protein-7 induces activation and transdifferentiation of hepatic stellate cells in vitro
LX Liu, S Huang, QQ Zhang, Y Liu, DM Zhang, XH Guo, DW Han |
World journal of gastroenterology : WJG | 2009 |
|
A spectrum of severe familial liver disorders associate with telomerase mutations
RT Calado, JA Regal, DE Kleiner, DS Schrump, NR Peterson, V Pons, SJ Chanock, PM Lansdorp, NS Young |
PloS one | 2009 |
|
Reactive oxygen and nitrogen species induce protein and DNA modifications driving arthrofibrosis following total knee arthroplasty
TA Freeman, J Parvizi, CJ Valle, MJ Steinbeck |
Fibrogenesis & Tissue Repair | 2009 |
|
Transforming growth factors beta coordinate cartilage and tendon differentiation in the developing limb mesenchyme
CI Lorda-Diez, JA Montero, C Martinez-Cue, JA Garcia-Porrero, JM Hurle |
The Journal of biological chemistry | 2009 |
|
Focus on collagen: in vitro systems to study fibrogenesis and antifibrosis _ state of the art
CZ Chen, M Raghunath |
Fibrogenesis & Tissue Repair | 2009 |
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Advanced periductal fibrosis from infection with the carcinogenic human liver fluke Opisthorchis viverrini correlates with elevated levels of interleukin-6
B Sripa, E Mairiang, B Thinkhamrop, T Laha, S Kaewkes, P Sithithaworn, S Tessana, A Loukas, PJ Brindley, JM Bethony |
Hepatology | 2009 |
|
The Transforming Growth Factor- Pathway Is a Common Target of Drugs That Prevent Experimental Diabetic Retinopathy
C Gerhardinger, Z Dagher, P Sebastiani, YS Park, M Lorenzi |
Diabetes | 2009 |
|
Dietary Salt Intake, Salt Sensitivity, and Cardiovascular Health
PW Sanders |
Hypertension | 2009 |
|
Cyclic GMP Kinase and RhoA Ser188 Phosphorylation Integrate Pro- and Antifibrotic Signals in Blood Vessels
N Sawada, H Itoh, K Miyashita, H Tsujimoto, M Sone, K Yamahara, ZP Arany, F Hofmann, K Nakao |
Molecular and cellular biology | 2009 |
|
Evaluation of Hepatic Fibrosis with Portal Pressure Gradient in Rats
Wang Y, Booth CJ, Kim H, Qiu M, Constable RT |
Magnetic Resonance in Medicine | 2009 |
|
Mechanism of dietary salt-mediated increase in intravascular production of TGF-beta1
WZ Ying, K Aaron, PW Sanders |
American journal of physiology. Renal physiology | 2008 |
|
The IL-33/ST2 pathway: therapeutic target and novel biomarker
R Kakkar, RT Lee |
Nature Reviews Drug Discovery | 2008 |
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Cellular and molecular mechanisms of fibrosis
TA Wynn |
The Journal of Pathology | 2008 |
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Vitamin D reduces the expression of collagen and key profibrotic factors by inducing an antifibrotic phenotype in mesenchymal multipotent cells
JN Artaza, KC Norris |
Journal of Endocrinology | 2008 |
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Collagen synthesis is suppressed in dermal fibroblasts by the human antimicrobial peptide LL-37
HJ Park, DH Cho, HJ Kim, JY Lee, BK Cho, SI Bang, SY Song, K Yamasaki, AD Nardo, RL Gallo |
Journal of Investigative Dermatology | 2008 |
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Immunologic and inflammatory mechanisms that drive asthma progression to remodeling
DH Broide |
Journal of Allergy and Clinical Immunology | 2008 |
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The cyclic AMP effector Epac integrates pro- and anti-fibrotic signals
U Yokoyama, HH Patel, NC Lai, N Aroonsakool, DM Roth, PA Insel |
Proceedings of the National Academy of Sciences | 2008 |
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Macrophage-secreted factors promote a profibrotic phenotype in human preadipocytes
M Keophiphath, V Achard, C Henegar, C Rouault, K Clément, D Lacasa |
Molecular Endocrinology | 2008 |
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Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity
C Henegar, J Tordjman, V Achard, D Lacasa, I Cremer, M Guerre-Millo, C Poitou, A Basdevant, V Stich, N Viguerie, D Langin, P Bedossa, JD Zucker, K Clement |
Genome biology | 2008 |
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Lysophosphatidic acid and renal fibrosis
JP Pradère, J Gonzalez, J Klein, P Valet, S Grès, D Salant, JL Bascands, JS Saulnier-Blache, JP Schanstra |
Biochimica et Biophysica Acta | 2008 |
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Hic-5 promotes the hypertrophic scar myofibroblast phenotype by regulating the TGF-beta1 autocrine loop
G Dabiri, DA Tumbarello, CE Turner, LV de Water |
Journal of Investigative Dermatology | 2008 |
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Combinatorial selection of a single stranded DNA thioaptamer targeting TGF-beta1 protein
J Kang, MS Lee, JA 3rd, BA Luxon, DG Gorenstein |
Bioorganic & Medicinal Chemistry Letters | 2008 |
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Skeletal metamorphosis in fibrodysplasia ossificans progressiva (FOP)
FS Kaplan, Q Shen, V Lounev, P Seemann, J Groppe, T Katagiri, RJ Pignolo, EM Shore |
Journal of Bone and Mineral Metabolism | 2008 |
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Welcome to Fibrogenesis & Tissue Repair
M Pinzani |
Fibrogenesis & Tissue Repair | 2008 |
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Caveolin-1, TGF-β receptor internalization, and the pathogenesis of systemic sclerosis
Del Galdo F, Lisanti MP, Jimenez SA |
Current Opinion in Rheumatology | 2008 |
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Genomic and proteomic profiling II: Comparative assessment of gene expression profiles in leiomyomas, keloids, and surgically-induced scars
X Luo, Q Pan, L Liu, N Chegini |
Reproductive Biology and Endocrinology | 2007 |
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