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Usage Information

Immune surveillance of tumors
Jeremy B. Swann, Mark J. Smyth
Jeremy B. Swann, Mark J. Smyth
Published May 1, 2007
Citation Information: J Clin Invest. 2007;117(5):1137-1146. https://doi.org/10.1172/JCI31405.
View: Text | PDF
Review Series Article has an altmetric score of 141

Immune surveillance of tumors

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Abstract

The ability of the immune system to identify and destroy nascent tumors, and to thereby function as a primary defense against cancer, has been debated for many decades. Recent findings by a number of investigators in both mouse models of cancer and humans with cancer now offer compelling evidence that particular immune cell types, effector molecules, and pathways can sometimes collectively function as extrinsic tumor suppressor mechanisms. This work provides the basis for further study of natural immunity to cancer and for rational use of this information in the design of immunotherapies in combination with other conventional cancer treatments.

Authors

Jeremy B. Swann, Mark J. Smyth

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Usage data is cumulative from May 2024 through May 2025.

Usage JCI PMC
Text version 4,342 2,825
PDF 305 265
Figure 481 10
Table 197 0
Citation downloads 138 0
Totals 5,463 3,100
Total Views 8,563
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Usage information is collected from two different sources: this site (JCI) and Pubmed Central (PMC). JCI information (compiled daily) shows human readership based on methods we employ to screen out robotic usage. PMC information (aggregated monthly) is also similarly screened of robotic usage.

Various methods are used to distinguish robotic usage. For example, Google automatically scans articles to add to its search index and identifies itself as robotic; other services might not clearly identify themselves as robotic, or they are new or unknown as robotic. Because this activity can be misinterpreted as human readership, data may be re-processed periodically to reflect an improved understanding of robotic activity. Because of these factors, readers should consider usage information illustrative but subject to change.

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