Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • Vascular Malformations (Apr 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact

Citations to this article

CCAAT enhancer- binding protein beta is required for normal hepatocyte proliferation in mice after partial hepatectomy.
L E Greenbaum, … , V Poli, R Taub
L E Greenbaum, … , V Poli, R Taub
Published September 1, 1998
Citation Information: J Clin Invest. 1998;102(5):996-1007. https://doi.org/10.1172/JCI3135.
View: Text | PDF
Research Article Article has an altmetric score of 3

CCAAT enhancer- binding protein beta is required for normal hepatocyte proliferation in mice after partial hepatectomy.

  • Text
  • PDF
Abstract

After two-thirds hepatectomy, normally quiescent liver cells are stimulated to reenter the cell cycle and proliferate to restore the original liver mass. The level of bZIP transcription factor CCAAT enhancer-binding protein beta (C/EBPbeta) increases in the liver during the period of cell proliferation. The significance of this change in C/EBP expression is not understood. To determine the role of C/EBPbeta in the regenerating liver, we examined the regenerative response after partial hepatectomy in mice that contain a targeted disruption of the C/EBPbeta gene. Posthepatectomy, hepatocyte DNA synthesis was decreased to 25% of normal in C/EBPbeta -/- mice. The reduced regenerative response was associated with a prolonged period of hypoglycemia that was independent of expression of C/EBPalpha protein and gluconeogenic genes. C/EBPbeta -/- livers showed reduced expression of immediate-early growth-control genes including the Egr-1 transcription factor, mitogen-activated protein kinase protein tyrosine phosphatase (MKP-1), and HRS, a delayed-early gene that encodes an mRNA splicing protein. Cyclin B and E gene expression were dramatically reduced in C/EBPbeta -/- livers whereas cyclin D1 expression was normal. The abnormalities in immediate-early gene expression in C/EBPbeta -/- livers were distinct from those seen in IL-6 -/- livers. These data link C/EBPbeta to the activation of metabolic and growth response pathways in the regenerating liver and demonstrate that C/EBPbeta is required for a normal proliferative response.

Authors

L E Greenbaum, W Li, D E Cressman, Y Peng, G Ciliberto, V Poli, R Taub

×

Total citations by year

Year: 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 Total
Citations: 3 7 5 3 6 1 9 5 3 6 8 6 4 15 12 15 19 5 11 17 9 16 13 20 7 13 1 239
Citation information
This citation data is accumulated from CrossRef, which receives citation information from participating publishers, including this journal. Not all publishers participate in CrossRef, so this information is not comprehensive. Additionally, data may not reflect the most current citations to this article, and the data may differ from citation information available from other sources (for example, Google Scholar, Web of Science, and Scopus).

Citations to this article (239)

Title and authors Publication Year
A Novel Role for the Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Delta Isoform in Hepatocellular Proliferation
Martucci NJ, Stoops J, Bowen W, Orr A, Cotner MC, Michalopoulos GK, Bhushan B, Mars WM
The American Journal of Pathology 2024
A critical role for HNF4α in polymicrobial sepsis-associated metabolic reprogramming and death.
Van Dender C, Timmermans S, Paakinaho V, Vanderhaeghen T, Vandewalle J, Claes M, Garcia B, Roman B, De Waele J, Croubels S, De Bosscher K, Meuleman P, Herpain A, Palvimo JJ, Libert C
EMBO molecular medicine 2024
Research progress on FSH-FSHR signaling in the pathogenesis of non-reproductive diseases
Li C, Ling Y, Kuang H
Frontiers in Cell and Developmental Biology 2024
C/EBPβ/AEP Pathway is Age-dependently Activated in Parkinson's Disease and Mediates Lewy Body Propagation from the Gut into the Brain
Hualong Wang, Eunhee Ahn, Yiyuan Xia, Xia Liu, Shengdi Chen, Keqiang Ye
npj Parkinson's Disease 2023
Dynamics and regulation of mitotic chromatin accessibility bookmarking at single-cell resolution.
Yu Q, Liu X, Fang J, Wu H, Guo C, Zhang W, Liu N, Jiang C, Sha Q, Yuan X, Wang Z, Qu K
Science Advances 2023
C/EBPβ deficiency enhances the keratinocyte innate immune response to direct activators of cytosolic pattern recognition receptors.
House JS, Gray S, Owen JR, Jima DD, Smart RC, Hall JR
Innate immunity 2023
A NRF2-induced secretory phenotype activates immune surveillance to remove irreparably damaged cells
Baird L, Taguchi K, Zhang A, Takahashi Y, Suzuki T, Kensler TW, Yamamoto M
Redox Biology 2023
Sepsis-induced endothelial dysfunction drives acute-on-chronic liver failure through Angiopoietin-2-HGF-C/EBPβ pathway.
Elias G, Schonfeld M, Saleh S, Parrish M, Barmanova M, Weinman SA, Tikhanovich I
Hepatology 2023
FSH and ApoE4 contribute to Alzheimer's disease-like pathogenesis via C/EBPβ/δ-secretase in female mice.
Xiong J, Kang SS, Wang M, Wang Z, Xia Y, Liao J, Liu X, Yu SP, Zhang Z, Ryu V, Yuen T, Zaidi M, Ye K
Nature Communications 2023
Characterisation of forkhead box protein A3 as a key transcription factor for hepatocyte regeneration.
Li G, Zhu L, Guo M, Wang D, Meng M, Zhong Y, Zhang Z, Lin Y, Liu C, Wang J, Zhang Y, Gao Y, Cao Y, Xia Z, Qiu J, Li Y, Liu S, Chen H, Liu W, Han Y, Zheng M, Ma X, Xu L
2023
The transcription factor CCAAT/enhancer-binding protein β in spinal microglia contributes to pre-operative stress-induced prolongation of postsurgical pain.
Jiang M, Huang Y, Hu L, Wu H, Liu Y, Ni K, Zhang X, Sun Y, Gu X
Molecular Pain 2022
Liver Regeneration: Changes in Oxidative Stress, Immune System, Cytokines, and Epigenetic Modifications Associated with Aging.
Tang C, Chen H, Jiang L, Liu L
Oxidative medicine and cellular longevity 2022
Immune cell C/EBPβ deficiency is associated with hepatic mononuclear defects and spontaneous hepatitis but not steatohepatitis induced liver fibrosis.
Moshkovits I, Kaminitz A, Reuveni D, Pasmanik-Chor M, Brazowski E, Mildner A, Leutz A, Zigmond E
Immunity, Inflammation and Disease 2022
β-(4-fluorobenzyl) Arteannuin B induced interaction of ATF-4 and C/EBPβ mediates the transition of breast cancer cells from autophagy to senescence.
Mir KB, Faheem MM, Ahmad SM, Rasool JU, Amin T, Chakraborty S, Bhagat M, Ahmed Z, Ali A, Goswami A
Frontiers in Oncology 2022
Role of the Hippo pathway in liver regeneration and repair: recent advances
Pibiri M, Simbula G
Ensho Saisei 2022
ApoE4 activates C/EBPβ/δ-secretase with 27-hydroxycholesterol, driving the pathogenesis of Alzheimer’s disease
ZH Wang, Y Xia, P Liu, X Liu, L Edgington-Mitchell, K Lei, SP Yu, XC Wang, K Ye
Progress in Neurobiology 2021
Multi-organ proteomic landscape of COVID-19 autopsies
X Nie, L Qian, R Sun, B Huang, X Dong, Q Xiao, Q Zhang, T Lu, L Yue, S Chen, X Li, Y Sun, L Li, L Xu, Y Li, M Yang, Z Xue, S Liang, X Ding, C Yuan, L Peng, W Liu, X Yi, M Lyu, G Xiao, X Xu, W Ge, J He, J Fan, J Wu, M Luo, X Chang, H Pan, X Cai, J Zhou, J Yu, H Gao, M Xie, S Wang, G Ruan, H Chen, H Su, H Mei, D Luo, D Zhao, F Xu, Y Li, Y Zhu, J Xia, Y Hu, T Guo
Cell 2021
Liver regeneration biology: Implications for liver tumour therapies
C Hadjittofi, M Feretis, J Martin, S Harper, E Huguet
World journal of clinical oncology 2021
C/EBPβ is a key transcription factor for APOE and preferentially mediates ApoE4 expression in Alzheimer’s disease
Y Xia, Z Wang, J Zhang, X Liu, SP Yu, KX Ye, JZ Wang, K Ye, XC Wang
Molecular Psychiatry 2020
CREBZF as a Key Regulator of STAT3 Pathway in the Control of Liver Regeneration in Mice
Z Hu, Y Han, Y Liu, Z Zhao, F Ma, A Cui, F Zhang, Z Liu, Y Xue, J Bai, H Wu, H Bian, YE Chin, Y Yu, Z Meng, H Wang, Y Liu, J Fan, X Gao, Y Chen, Y Li
Hepatology 2020
Metabolic impairment in response to early induction of C/EBPβ leads to compromised cardiac function during pathological hypertrophy
D Banerjee, RD Chaudhuri, S Niyogi, SR Chowdhuri, MP Sarkar, R Chatterjee, P Chakrabarti, S Sarkar
Journal of Molecular and Cellular Cardiology 2020
An unbiased lipidomics approach identifies key lipid molecules as potential therapeutic targets of Dohongsamul-tang against non-alcoholic fatty liver diseases in a mouse model of obesity
S Park, JE Lee, SM Lee, J Lee, CS Seo, GS Hwang, J Jung
Journal of Ethnopharmacology 2020
Recipient interleukin 6 gene polymorphism and expression predict HCV recurrence post liver transplantation
RM Dawood, GM Salum, MA El-Meguid, M Shemis, AO Aziz, MK Awady
Gene 2020
DDIT3 modulates cancer stemness in gastric cancer by directly regulating CEBPβ
H Lin, S Liu, W Gao, H Liu
The Journal of pharmacy and pharmacology 2020
C/EBPβ Is a Transcriptional Regulator of Wee1 at the G2/M Phase of the Cell Cycle
JH Lee, JY Sung, EK Choi, HK Yoon, BR Kang, EK Hong, BK Park, YN Kim, SB Rho, K Yoon
Cells 2019
Serum interleukin-6 and tumor necrosis factor-α are associated with early graft regeneration after living donor liver transplantation
MS Chae, KU Moon, HS Chung, CS Park, J Lee, JH Choi, SH Hong, GD Alpini
PloS one 2018
Post-hepatectomy liver regeneration in the context of bile acid homeostasis and the gut-liver signaling axis
H Jaeschke, T Li, M Heger
Journal of Clinical and Translational Research 2018
Liver regeneration in aged mice: new insights
Monica Pibiri
Aging 2018
Liver regeneration in aged mice: new insights
Pibiri M
Aging 2018
Responses of Transgenic Melatonin-Enriched Goats on LPS Stimulation and the Proteogenomic Profiles of Their PBMCs
M Yang, J Tao, H Wu, L Zhang, Y Yao, L Liu, T Zhu, H Fan, X Cui, H Dou, G Liu
International journal of molecular sciences 2018
C/EBPβ regulates delta-secretase expression and mediates pathogenesis in mouse models of Alzheimer’s disease
ZH Wang, K Gong, X Liu, Z Zhang, X Sun, ZZ Wei, SP Yu, FP Manfredsson, IM Sandoval, PF Johnson, J Jia, JZ Wang, K Ye
Nature Communications 2018
A Pre-Clinical Large Animal Model of Sustained Liver Injury and Regeneration Stimulus
K Inomata, K Tajima, H Yagi, H Higashi, H Shimoda, K Matsubara, T Hibi, Y Abe, H Tsujikawa, M Kitago, M Shinoda, H Obara, O Itano, A Soto-Gutierrez, Y Kitagawa
Scientific Reports 2018
CCAAT-Enhancer Binding Protein-beta (C/EBPP) Regulates Deltasecretase Expression, Mediating the Pathogenesis in Alzheimer's Disease
ZH Wang, K Gong, X Liu, Z Zhang, X Sun, SP Yu, FP Manfredsson, IM Sandoval, PF Johnson, J Jia, JZ Wang, K Ye
SSRN Electronic Journal 2018
Liver regeneration in aged mice: new insights
M Pibiri
Aging 2018
C/EBPβ-1 promotes transformation and chemoresistance in Ewing sarcoma cells
JD Gardiner, LM Abegglen, X Huang, BE Carter, EA Schackmann, M Stucki, CN Paxton, RL Randall, JF Amatruda, AR Putnam, H Kovar, SL Lessnick, JD Schiffman
Oncotarget 2017
EMMPRIN (CD147) is induced by C/EBPβ and is differentially expressed in ALK+ and ALK− anaplastic large-cell lymphoma
J Schmidt, I Bonzheim, J Steinhilber, IA Montes-Mojarro, C Ortiz-Hidalgo, W Klapper, F Fend, L Quintanilla-Martínez
Laboratory Investigation 2017
Role of early growth response 1 in liver metabolism and liver cancer
N Magee, Y Zhang
Hepatoma Research 2017
EMMPRIN (CD147) is induced by C/EBPβ and is differentially expressed in ALK+ and ALK- anaplastic large-cell lymphoma.
Schmidt J, Bonzheim I, Steinhilber J, Montes-Mojarro IA, Ortiz-Hidalgo C, Klapper W, Fend F, Quintanilla-Martínez L
Laboratory Investigation 2017
Identification of a new liver-specific c-type mRNA transcriptional variant for mouse ST3GAL5 (GM3/GM4 synthase).
Shishido F, Uemura S, Nitta T, Inokuchi JI
Glycoconjugate Journal 2017
A novel comparative pattern analysis approach identifies chronic alcohol mediated dysregulation of transcriptomic dynamics during liver regeneration
L Kuttippurathu, E Juskeviciute, RP Dippold, JB Hoek, R Vadigepalli
BMC Genomics 2016
Postponing the Hypoglycemic Response to Partial Hepatectomy Delays Mouse Liver Regeneration
J Huang, AE Schriefer, PF Cliften, D Dietzen, S Kulkarni, S Sing, SP Monga, DA Rudnick
The American Journal of Pathology 2016
Pattern analysis uncovers a chronic ethanol-induced disruption of the switch-like dynamics of C/EBP-β and C/EBP-α genome-wide binding during liver regeneration
L Kuttippurathu, B Patra, D Cook, JB Hoek, R Vadigepalli
Physiological genomics 2016
CCAAT/Enhancer Binding Protein β Is Dispensable for Development of Lung Adenocarcinoma
Y Cai, A Hirata, S Nakayama, PA VanderLaan, E Levantini, M Yamamoto, H Hirai, KK Wong, DB Costa, H Watanabe, SS Kobayashi, VV Kalinichenko
PloS one 2015
CCAAT/Enhancer Binding Protein β in relation to ER Stress, Inflammation, and Metabolic Disturbances
SE van der Krieken, HE Popeijus, RP Mensink, J Plat
BioMed Research International 2015
Next-Generation Sequencing Identifies Deregulation of MicroRNAs Involved in Both Innate and Adaptive Immune Response in ALK+ ALCL
J Steinhilber, M Bonin, M Walter, F Fend, I Bonzheim, L Quintanilla-Martinez, DY Jin
PloS one 2015
Regulation of hepatocyte identity and quiescence
C Berasain, MA Avila
Cellular and Molecular Life Sciences 2015
Accelerated apoptosis of peripheral blood monocytes in Cebpb-deficient mice
A Tamura, H Hirai, A Yokota, A Sato, T Shoji, T Kashiwagi, M Iwasa, A Fujishiro, Y Miura, T Maekawa
Biochemical and Biophysical Research Communications 2015
Regulation of Mice Liver Regeneration by Early Growth Response-1 through the GGPPS/RAS/MAPK Pathway
S Lai, J Yuan, D Zhao, N Shen, W Chen, Y Ding, D Yu, J Li, F Pan, M Zhu, C Li, B Xue
The International Journal of Biochemistry & Cell Biology 2015
Regenerative Medicine Applications in Organ Transplantation
L Brasile
Regenerative Medicine Applications in Organ Transplantation 2014
Specific NuRD components are required for fin regeneration in zebrafish
C Pfefferli, F Müller, A Jaźwińska, C Wicky
BMC Biology 2014
An integrated approach for the identification of USF1-centered transcriptional regulatory networks during liver regeneration
H Chen, S Lu, J Zhou, Z Bai, H Fu, X Xu, S Yang, B Jiao, Y Sun
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 2014
Apigenin isolated from Daphne genkwa Siebold et Zucc. inhibits 3T3-L1 preadipocyte differentiation through a modulation of mitotic clonal expansion
MA Kim, K Kang, HJ Lee, M Kim, CY Kim, CW Nho
Life Sciences 2014
Downregulation of hepatic stimulator substance during the early phase of liver regeneration inhibits E-cadherin expression in mice
H Zhang, L Dong, G Sun, W An
The International Journal of Biochemistry & Cell Biology 2014
C/EBPβ knockdown protects cardiomyocytes from hypertrophy via inhibition of p65-NFκB
J Zou, H Li, X Chen, S Zeng, J Ye, C Zhou, M Liu, L Zhang, N Yu, X Gan, H Zhou, Z Xian, S Chen, P Liu
Molecular and Cellular Endocrinology 2014
Protein tyrosine phosphatase of liver regeneration-1 is required for normal timing of cell cycle progression during liver regeneration
Y Jiao, DZ Ye, Z Li, M Teta-Bissett, Y Peng, R Taub, LE Greenbaum, KH Kaestner
AJP Gastrointestinal and Liver Physiology 2014
CCAAT/enhancer-binding protein β regulates interleukin-6-induced transmembrane and ubiquitin-like domain containing 1 gene expression in hepatocytes
M Liu, T Yuan, H Liu, P Chen
Molecular medicine reports 2014
Identification of C/EBPβ target genes in ALK+ anaplastic large cell lymphoma (ALCL) by gene expression profiling and chromatin immunoprecipitation
I Bonzheim, M Irmler, M Klier-Richter, J Steinhilber, N Anastasov, S Schäfer, P Adam, J Beckers, M Raffeld, F Fend, L Quintanilla-Martinez
PloS one 2013
Age-associated Change of C/EBP Family Proteins Causes Severe Liver Injury and Acceleration of Liver Proliferation after CCl4 Treatments
IH Hong, K Lewis, P Iakova, J Jin, E Sullivan, N Jawanmardi, L Timchenko, N Timchenko
The Journal of biological chemistry 2013
Temporal mapping of CEBPA and CEBPB binding during liver regeneration reveals dynamic occupancy and specific regulatory codes for homeostatic and cell cycle gene batteries
JS Jakobsen, J Waage, N Rapin, HC Bisgaard, FS Larsen, BT Porse
Genome research 2013
Upregulated microRNA-92b regulates the differentiation and proliferation of EpCAM-positive fetal liver cells by targeting C/EBPß
NS Qian, WH Liu, WP Lv, X Xiang, M Su, V Raut, YL Chen, JH Dong
PloS one 2013
Identification of C/EBPβ Target Genes in ALK+ Anaplastic Large Cell Lymphoma (ALCL) by Gene Expression Profiling and Chromatin Immunoprecipitation
I Bonzheim, M Irmler, M Klier-Richter, J Steinhilber, N Anastasov, S Schäfer, P Adam, J Beckers, M Raffeld, F Fend, L Quintanilla-Martinez, JA Climent
PloS one 2013
Upregulated MicroRNA-92b Regulates the Differentiation and Proliferation of EpCAM-Positive Fetal Liver Cells by Targeting C/EBPß
NS Qian, WH Liu, WP Lv, X Xiang, M Su, V Raut, YL Chen, JH Dong, LY Yang
PloS one 2013
Regulation of Human Endometrial Stromal Proliferation and Differentiation by C/EBPβ Involves Cyclin E-cdk2 and STAT3
W Wang, RN Taylor, IC Bagchi, MK Bagchi
Molecular Endocrinology 2012
Foxa2 and H2A.Z Mediate Nucleosome Depletion during Embryonic Stem Cell Differentiation
Z Li, P Gadue, K Chen, Y Jiao, G Tuteja, J Schug, W Li, KH Kaestner
Cell 2012
High dosing of α -tocopherol inhibits rat liver regeneration by modifying signal transducer and activator of transcription protein expression and its correlation with cell redox state and retinoid metabolism
L Sánchez-Sevilla, E Mendieta-Condado, R Hernández-Muñoz
Experimental biology and medicine (Maywood, N.J.) 2012
Mechanical and Chemical Signaling in Angiogenesis
CA Reinhart-King
2012
Interleukin-1 Receptor Antagonist Modulates the Early Phase of Liver Regeneration after Partial Hepatectomy in Mice
A Sgroi, C Gonelle-Gispert, P Morel, RM Baertschiger, N Niclauss, G Mentha, P Majno, V Serre-Beinier, L Buhler
PloS one 2011
The influence of skeletal muscle on the regulation of liver:body mass and liver regeneration
J Huang, M Glauber, Z Qiu, V Gazit, DJ Dietzen, DA Rudnick
The American Journal of Pathology 2011
The nucleosome map of the mammalian liver
Z Li, J Schug, G Tuteja, P White, KH Kaestner
Nature Structural & Molecular Biology 2011
The Reduction of SIRT1 in Livers of Old Mice Leads to Impaired Body Homeostasis and to Inhibition of Liver Proliferation
J Jin, P Iakova, Y Jiang, EE Medrano, NA Timchenko
Hepatology 2011
Advances in the regulation of liver regeneration
C Jia
Expert Review of Gastroenterology & Hepatology 2011
Progress of transcription factor CCAAT enhancer binding protein β
YZ GAO, YC PAN
Hereditas (Beijing) 2011
Pro-inflammatory gene expression and neurotoxic effects of activated microglia are attenuated by absence of CCAAT/enhancer binding protein β
M Straccia, N Gresa-Arribas, G Dentesano, A Ejarque-Ortiz, JM Tusell, J Serratosa, C Solà, J Saura
Journal of Neuroinflammation 2011
Impaired activities of cyclic adenosine monophosphate-responsive element binding protein, protein kinase A and calcium-independent phospholipase A2 are involved in deteriorated regeneration of cirrhotic liver after partial hepatectomy in rats : CREB dysfunction in regenerating cirrhotic liver
G Zhao, R Wakabayashi, S Shimoda, Y Fukunaga, M Kumagai, M Tanaka, K Nakano
Hepatology Research 2011
Advances in Cancer Research
M Lemaire, S Deleu, ED Bruyne, EV Valckenborgh, E Menu, K Vanderkerken
Advances in Cancer Research Volume 110 2011
Role of C/EBPβ Transcription Factor in Adult Hippocampal Neurogenesis
M Cortes-Canteli, D Aguilar-Morante, M Sanz-Sancristobal, D Megias, A Santos, A Perez-Castillo
PloS one 2011
Ursolic acid enhances mouse liver regeneration after partial hepatectomy
YR Jin, J Jin, CH Li, XX Piao, NG Jin
Pharmaceutical Biology 2011
Vitamins &amp Hormones
N Kawaguchi
Stem Cell Regulators 2011
C/EBPbeta’s role in determining Ras-induced senescence or transformation
AA Atwood, L Sealy
Small GTPases 2011
Role of C/EBPβ Transcription Factor in Adult Hippocampal Neurogenesis
M Cortes-Canteli, D Aguilar-Morante, M Sanz-SanCristobal, D Megias, A Santos, A Perez-Castillo, CV Borlongan
PloS one 2011
Transcriptional activation of histone H4 by C/EBPβ during the mitotic clonal expansion of 3T3-L1 adipocyte differentiation
YY Zhang, , SW Qian, L Guo, HY Huang, Q He, Y Liu, CG Ma, QQ Tang, WP Tansey
Molecular biology of the cell 2011
Tob1 is a constitutively expressed repressor of liver regeneration
KJ Ho, NL Do, HH Otu, MJ Dib, X Ren, K Enjyoji, SC Robson, EF Terwilliger, SJ Karp
Journal of Experimental Medicine 2010
Inductive angiocrine signals from sinusoidal endothelium are required for liver regeneration
BS Ding, DJ Nolan, JM Butler, D James, AO Babazadeh, Z Rosenwaks, V Mittal, H Kobayashi, K Shido, D Lyden, TN Sato, SY Rabbany, S Rafii
Nature 2010
Epidermal growth factor down-regulates the expression of human hepatic stimulator substance via CCAAT/enhancer-binding protein β in HepG2 cells
L Dong, G Sun, L Jiang, L Shao, Y Hu, Y Jiang, Y Wang, W An
Biochemical Journal 2010
Transcription factor Smad3 is required for the inhibition of adipogenesis by retinoic acid
F Marchildon, C St-Louis, R Akter, V Roodman, NL Wiper-Bergeron
The Journal of biological chemistry 2010
Calmodulin controls liver proliferation via interactions with C/EBPbeta-LAP and C/EBPbeta-LIP
D Orellana, X Liu, GL Wang, J Jin, P Iakova, NA Timchenko
The Journal of biological chemistry 2010
C/EBPbetaDeltauORF mice--a genetic model for uORF-mediated translational control in mammals
K Wethmar, V Bégay, JJ Smink, K Zaragoza, V Wiesenthal, B Dörken, CF Calkhoven, A Leutz
Genes & development 2010
Transcriptional and translational control of C/EBPs: The case for “deep” genetics to understand physiological function
C Nerlov
BioEssays 2010
Calmodulin Controls Liver Proliferation via Interactions with C/EBPβ-LAP and C/EBPβ-LIP
D Orellana, X Liu, GL Wang, J Jin, P Iakova, NA Timchenko
The Journal of biological chemistry 2010
Molecular Pathology of Liver Diseases
SP Monga
2010
The CCAAT/Enhancer Binding Protein β Is a Critical Regulator of Steroid-Induced Mitotic Expansion of Uterine Stromal Cells during Decidualization
W Wang, Q Li, IC Bagchi, MK Bagchi
Endocrinology 2010
Lack of CCAAT Enhancer Binding Protein Beta (C/EBPβ) in Uterine Epithelial Cells Impairs Estrogen-Induced DNA Replication, Induces DNA Damage Response Pathways, and Promotes Apoptosis
C Ramathal, IC Bagchi, MK Bagchi
Molecular and cellular biology 2010
RSK-Mediated Phosphorylation in the C/EBPβ Leucine Zipper Regulates DNA Binding, Dimerization, and Growth Arrest Activity
S Lee, JD Shuman, T Guszczynski, K Sakchaisri, T Sebastian, TD Copeland, M Miller, MS Cohen, J Taunton, RC Smart, Z Xiao, LR Yu, TD Veenstra, PF Johnson
Molecular and cellular biology 2010
Mesenchymal stromal cells as supportive cells for hepatocytes
A Gómez-Aristizábal, A Keating, JE Davies
Molecular Therapy 2009
Reactive oxygen species facilitate adipocyte differentiation by accelerating mitotic clonal expansion
H Lee, YJ Lee, H Choi, EH Ko, JW Kim
The Journal of biological chemistry 2009
CCAAT/enhancer-binding protein β: its role in breast cancer and associations with receptor tyrosine kinases
CA Zahnow
Expert Reviews in Molecular Medicine 2009
p21 is required for dextrose-mediated inhibition of mouse liver regeneration
A Weymann, E Hartman, V Gazit, C Wang, M Glauber, Y Turmelle, DA Rudnick
Hepatology 2009
Relationships between deficits in tissue mass and transcriptional programs after partial hepatectomy in mice
J Li, JS Campbell, C Mitchell, RS McMahan, X Yu, KJ Riehle, RE Bumgarner, N Fausto
The American Journal of Pathology 2009
O-linked N-acetylglucosamine modification on CCAAT enhancer-binding protein beta: role during adipocyte differentiation
X Li, H Molina, H Huang, YY Zhang, M Liu, SW Qian, C Slawson, WB Dias, A Pandey, GW Hart, MD Lane, QQ Tang
The Journal of biological chemistry 2009
Misexpression of CCAAT/enhancer binding protein beta causes osteopenia
S Zanotti, L Stadmeyer, A Smerdel-Ramoya, D Durant, E Canalis
The Journal of endocrinology 2009
CCAAT enhancer-binding protein alpha is a molecular target of 1,25-dihydroxyvitamin D3 in MCF-7 breast cancer cells
P Dhawan, R Wieder, R Weider, S Christakos
The Journal of biological chemistry 2009
FoxF1 and FoxL1 link hedgehog signaling and the control of epithelial proliferation in the developing stomach and intestine
BB Madison, LB McKenna, D Dolson, DJ Epstein, KH Kaestner
The Journal of biological chemistry 2009
Genomic response of the rat brain to global ischemia and reperfusion
F Büttner, C Cordes, F Gerlach, A Heimann, B Alessandri, U Luxemburger, Ö Türeci, T Hankeln, O Kempski, T Burmester
Brain Research 2009
Aging and liver regeneration
NA Timchenko
Trends in Endocrinology & Metabolism 2009
Oltipraz promotion of liver regeneration after partial hepatectomy: The role of PI3-kinase-dependent C/EBPβ and cyclin E regulation
IJ Cho, DK Sung, KW Kang, SG Kim
Archives of Pharmacal Research 2009
O -Linked N -Acetylglucosamine Modification on CCAAT Enhancer-binding Protein β: ROLE DURING ADIPOCYTE DIFFERENTIATION
X Li, H Molina, H Huang, Y Zhang, M Liu, S Qian, C Slawson, WB Dias, A Pandey, GW Hart, MD Lane, QQ Tang
The Journal of biological chemistry 2009
Reactive Oxygen Species Facilitate Adipocyte Differentiation by Accelerating Mitotic Clonal Expansion
H Lee, YJ Lee, H Choi, EH Ko, J Kim
The Journal of biological chemistry 2009
Cyclic regulation of transcription factor C/EBP beta in human endometrium
BJ Plante, A Kannan, MK Bagchi, L Yuan, SL Young
Reproductive Biology and Endocrinology 2009
Tissue-specific transcription factors in progression of epithelial tumors
NL Lazarevich, DI Fleishman
Biochemistry (Moscow) 2008
Temporal and functional profile of the transcriptional regulatory network in the early regenerative response to partial hepatectomy in the rat
E Juskeviciute, R Vadigepalli, JB Hoek
BMC Genomics 2008
HDAC1 promotes liver proliferation in young mice via interactions with C/EBPbeta
GL Wang, E Salisbury, X Shi, L Timchenko, EE Medrano, NA Timchenko
The Journal of biological chemistry 2008
Transcription factor early growth response-1 induction mediates inflammatory gene expression and brain damage following transient focal ischemia
K Tureyen, N Brooks, K Bowen, J Svaren, R Vemuganti
Journal of Neurochemistry 2008
Reduced liver injury in the interleukin-6 knockout mice by chronic carbon tetrachloride administration
A Río, MA Gassull, X Aldeguer, I Ojanguren, E Cabré, E Fernández
European Journal of Clinical Investigation 2008
Involvement of CCAAT/enhancer binding protein-β (C/EBPβ) in epigenetic regulation of mouse methionine adenosyltransferase 1A gene expression
R Ikeda, T Nishida, F Watanabe, K Shimizu-Saito, K Asahina, S Horikawa, H Teraoka
The International Journal of Biochemistry & Cell Biology 2008
Up-regulation of hepatic heme oxygenase-1 expression by locally induced interleukin-6 in rats administered carbon tetrachloride intraperitoneally
K Yamaji, Y Ochiai, K Ohnishi, A Yawata, T Chikuma, H Hojo
Toxicology Letters 2008
A mesoscale model of G1/S phase transition in liver regeneration
A Chauhan, S Legewie, PÅ Westermark, S Lorenzen, H Herzel
Journal of Theoretical Biology 2008
G9a-mediated Lysine Methylation Alters the Function of CCAAT/Enhancer-binding Protein-β*S⃞
O Pless, E Kowenz-Leutz, M Knoblich, J Lausen, M Beyermann, MJ Walsh, A Leutz
The Journal of biological chemistry 2008
Estradiol induces type 8 17 -hydroxysteroid dehydrogenase expression: crosstalk between estrogen receptor   and C/EBP 
M Rotinen, J Celay, MM Alonso, A Arrazola, I Encio, J Villar
Journal of Endocrinology 2008
The identification of C/EBPβ as a transcription factor necessary for the induction of MAPK phosphatase-1 by toll-like receptor-4 ligand
IJ Cho, NR Woo, SG Kim
Archives of Biochemistry and Biophysics 2008
Deprivation of protein or amino acid induces C/EBPbeta synthesis and binding to amino acid response elements, but its action is not an absolute requirement for enhanced transcription
MM Thiaville, EE Dudenhausen, C Zhong, YX Pan, MS Kilberg
Biochemical Journal 2008
Alterations of Notch/Jagged mRNA and protein expression after partial hepatectomy in rats
HY Xu, BJ Li, RF Wang, R Andersson
Scandinavian Journal of Gastroenterology 2008
G9a-mediated Lysine Methylation Alters the Function of CCAAT/Enhancer-binding Protein-β
O Pless, E Kowenz-Leutz, M Knoblich, J Lausen, M Beyermann, MJ Walsh, A Leutz
The Journal of biological chemistry 2008
HDAC1 Promotes Liver Proliferation in Young Mice via Interactions with C/EBPβ
GL Wang, E Salisbury, X Shi, L Timchenko, EE Medrano, NA Timchenko
The Journal of biological chemistry 2008
CCAAT Enhancer-binding Protein α Is a Molecular Target of 1,25-Dihydroxyvitamin D 3 in MCF-7 Breast Cancer Cells
P Dhawan, R Weider, S Christakos
The Journal of biological chemistry 2008
FoxF1 and FoxL1 Link Hedgehog Signaling and the Control of Epithelial Proliferation in the Developing Stomach and Intestine
BB Madison, LB McKenna, D Dolson, DJ Epstein, KH Kaestner
The Journal of biological chemistry 2008
CCAAT/Enhancer Binding Protein-β Is a Transcriptional Regulator of Peroxisome-Proliferator-Activated Receptor-γ Coactivator-1α in the Regenerating Liver
H Wang, TH Peiris, A Mowery, JL Lay, Y Gao, LE Greenbaum
Molecular Endocrinology 2008
Deprivation of protein or amino acid induces C/EBPβ synthesis and binding to amino acid response elements, but its action is not an absolute requirement for enhanced transcription
MM Thiaville, EE Dudenhausen, C Zhong, YX Pan, MS Kilberg
Biochemical Journal 2008
Role of STAT3 in liver regeneration: survival, DNA synthesis, inflammatory reaction and liver mass recovery
A Moh, Y Iwamoto, GX Chai, SS Zhang, A Kano, DD Yang, W Zhang, J Wang, JJ Jacoby, B Gao, RA Flavell, XY Fu
Laboratory Investigation 2007
C/EBPδ regulates cell cycle and self-renewal of human limbal stem cells
V Barbaro, A Testa, ED Iorio, F Mavilio, G Pellegrini, MD Luca
The Journal of Cell Biology 2007
Restoration of Liver Mass after Injury Requires Proliferative and Not Embryonic Transcriptional Patterns
HH Otu, K Naxerova, K Ho, H Can, N Nesbitt, TA Libermann, SJ Karp
The Journal of biological chemistry 2007
C/EBPβ Activates E2F-regulated Genes in Vivo via Recruitment of the Coactivator CREB-binding Protein/P300
H Wang, B Larris, TH Peiris, L Zhang, JL Lay, Y Gao, LE Greenbaum
The Journal of biological chemistry 2007
An Intronic Locus Control Region Plays an Essential Role in the Establishment of an Autonomous Hepatic Chromatin Domain for the Human Vitamin D-Binding Protein Gene
T Hiroki, SA Liebhaber, NE Cooke
Molecular and cellular biology 2007
Molecular and functional validation of Anaplastic Lymphoma Kinase (ALK) signature: identification of CEBPB and BCL2A1 as critical target genes
Roberto Piva, Elisa Pellegrino, Michela Mattioli, Luca Agnelli, Luigia Lombardi, Francesco Boccalatte, Giulia Costa, Bruce A. Ruggeri, Mangeng Cheng, Roberto Chiarle, Giorgio Palestro, Antonino Neri, and Giorgio Inghirami
Journal of Clinical Investigation 2006
Concerted functions of Gab1 and Shp2 in liver regeneration and hepatoprotection
EA Bard-Chapeau, J Yuan, N Droin, S Long, EE Zhang, TV Nguyen, GS Feng
Molecular and cellular biology 2006
Rosiglitazone inhibits mouse liver regeneration
YP Turmelle, O Shikapwashya, S Tu, PW Hruz, Q Yan, DA Rudnick
The FASEB Journal 2006
Urokinase-type plasminogen activator supports liver repair independent of its cellular receptor
K Shanmukhappa, GE Sabla, JL Degen, JA Bezerra
BMC Gastroenterology 2006
c-Jun/AP-1 controls liver regeneration by repressing p53/p21 and p38 MAPK activity
E Stepniak, R Ricci, R Eferl, G Sumara, I Sumara, M Rath, L Hui, EF Wagner
Genes & development 2006
CCAAT/enhancer-binding protein mediates carbon monoxide-induced suppression of cyclooxygenase-2
GY Suh, Y Jin, AK Yi, XM Wang, AM Choi
American journal of respiratory cell and molecular biology 2006
C/EBPbeta is a critical mediator of steroid hormone-regulated cell proliferation and differentiation in the uterine epithelium and stroma
SR Mantena, A Kannan, YP Cheon, Q Li, PF Johnson, IC Bagchi, MK Bagchi
Proceedings of the National Academy of Sciences 2006
C/EBPβ is required for 'emergency' granulopoiesis
H Hirai, P Zhang, T Dayaram, CJ Hetherington, S Mizuno, J Imanishi, K Akashi, DG Tenen
Nature Immunology 2006
Lactacystin inhibits 3T3-L1 adipocyte differentiation through induction of CHOP-10 expression
X Li, HY Huang, JG Chen, L Jiang, HL Liu, DG Liu, TJ Song, Q He, CG Ma, D Ma, HY Song, QQ Tang
Biochemical and Biophysical Research Communications 2006
Expression patterns of cytokine, growth factor and cell cycle-related genes after partial hepatectomy in rats with thioacetamide-induced cirrhosis
S Yang, CK Leow, TM Tan
World journal of gastroenterology : WJG 2006
Blockage of oncostatin M-induced LDL receptor gene transcription by a dominant-negative mutant of C/EBPβ
Y Zhou, F Zhang, P Abidi, M Lin, G Thiel, J Liu
Biochemical Journal 2006
A high-fat diet impairs liver regeneration in C57BL/6 mice through overexpression of the NF-kappaB inhibitor, IkappaBalpha
RA DeAngelis, MM Markiewski, R Taub, JD Lambris
Hepatology 2005
A20 protects mice from lethal radical hepatectomy by promoting hepatocyte proliferation via a p21waf1-dependent mechanism
CR Longo, VI Patel, GV Shrikhande, ST Scali, E Csizmadia, S Daniel, DW Sun, ST Grey, MB Arvelo, C Ferran
Hepatology 2005
Hepatic to pancreatic switch defines a role for hemostatic factors in cellular plasticity in mice
K Shanmukhappa, R Mourya, GE Sabla, JL Degen, JA Bezerra
Proceedings of the National Academy of Sciences 2005
Inhibition of Albumin Synthesis in Chronic Diseases
M Chojkier
Journal of Clinical Gastroenterology 2005
Characterization of liver function in transdifferentiated hepatocytes
ZD Burke, CN Shen, KL Ralphs, D Tosh
Journal of Cellular Physiology 2005
C/EBPbeta cooperates with RB:E2F to implement Ras(V12)-induced cellular senescence
T Sebastian, R Malik, S Thomas, J Sage, PF Johnson
The EMBO Journal 2005
Trimming the fat from liver regeneration
DA Rudnick
Hepatology 2005
Stimulation of hepatocyte survival and suppression of CCl4-induced liver injury by the adenovirally introduced C/EBPβ gene
K Isoda, H Koide, M Kojima, E Arita, M Ikkaku, S Higashiyama, F Tashiro, E Yamato, JI Miyazaki, M Kawase, K Yagi
Biochemical and Biophysical Research Communications 2005
The CAR nuclear receptor and hepatocyte proliferation
RH Costa, VV Kalinchenko, Y Tan, IC Wang
Hepatology 2005
Lack of therapeutic improvement of liver fibrosis in rats by dexamethasone in spite of ascites amelioration
SH Ki, DW Choi, CW Kim, SG Kim
Chemico-Biological Interactions 2005
Regulatory role of CCAAT/enhancer binding protein-β in the production of plasma proteins in yolk sac tumor
K Hirashiki, T Kishimoto, H Ishiguro, Y Nagai, M Furuya, S Sekiya, H Ishikura
Experimental and Molecular Pathology 2005
C/EBPβ contributes to hepatocyte growth factor-induced replication of rodent hepatocytes
B Wang, C Gao, KP Ponder
Journal of Hepatology 2005
Cell Cycle Defects Contribute to a Block in Hormone-induced Mammary Gland Proliferation in CCAAT/Enhancer-binding Protein (C/EBPβ)-null Mice
SL Grimm, A Contreras, MH Barcellos-Hoff, JM Rosen
The Journal of biological chemistry 2005
RNA CUG-binding Protein 1 Increases Translation of 20-kDa Isoform of CCAAT/Enhancer-binding Protein β by Interacting with the α and β Subunits of Eukaryotic Initiation Translation Factor 2
NA Timchenko, GL Wang, LT Timchenko
The Journal of biological chemistry 2005
Signaling Pathways in Liver Diseases
JF Dufour, PA Clavien, C Trautwein, R Graf
2005
C/EBPbeta-2 confers EGF-independent growth and disrupts the normal acinar architecture of human mammary epithelial cells
L Bundy, S Wells, L Sealy
Molecular Cancer 2005
Transcriptional Networks in the Liver: Hepatocyte Nuclear Factor 6 Function Is Largely Independent of Foxa2
NE Rubins, JR Friedman, PP Le, L Zhang, J Brestelli, KH Kaestner
Molecular and cellular biology 2005
Met provides essential signals for liver regeneration
M Borowiak, AN Garratt, T Wüstefeld, M Strehle, C Trautwein, C Birchmeier
Proceedings of the National Academy of Sciences 2004
Liver regeneration: from myth to mechanism
R Taub
Nature Reviews Molecular Cell Biology 2004
Orthogonal analysis of C/EBPbeta targets in vivo during liver proliferation
JR Friedman, B Larris, PP Le, TH Peiris, A Arsenlis, J Schug, JW Tobias, KH Kaestner, LE Greenbaum
Proceedings of the National Academy of Sciences 2004
C/EBP beta isoforms LIP and LAP modulate progression of the cell cycle in the regenerating mouse liver
T Luedde, M Duderstadt, KL Streetz, F Tacke, S Kubicka, MP Manns, C Trautwein
Hepatology 2004
Disruption of hepatic adipogenesis is associated with impaired liver regeneration in mice
E Shteyer, Y Liao, LJ Muglia, PW Hruz, DA Rudnick
Hepatology 2004
Transcriptional reprogramming in murine liver defines the physiologic consequences of biliary obstruction
KM Campbell, GE Sabla, JA Bezerra
Journal of Hepatology 2004
Role of MAPK Phosphatase-1 (MKP-1) in Adipocyte Differentiation
H Sakaue, W Ogawa, T Nakamura, T Mori, K Nakamura, M Kasuga
The Journal of biological chemistry 2004
Identification of Transcriptional Networks during Liver Regeneration
P White, JE Brestelli, KH Kaestner, LE Greenbaum
The Journal of biological chemistry 2004
Critical Prosurvival Roles for C/EBPβ and Insulin-Like Growth Factor I in Macrophage Tumor Cells
J Wessells, S Yakar, PF Johnson
Molecular and cellular biology 2004
Massive Hepatic Apoptosis After Fas Ligand Treatment in Insulin-Like Growth Factor Binding Protein-1 Deficient Mice Associated with Activated Matrix Metalloproteinase-9 and Transforming Growth Factor-b1
Julia I. Leu, Mary Ann S. Crissey, Rebecca Taub
Journal of Clinical Investigation 2003
Dominant-negative C/EBP disrupts mitotic clonal expansion and differentiation of 3T3-L1 preadipocytes
JW Zhang, QQ Tang, C Vinson, MD Lane
Proceedings of the National Academy of Sciences 2003
The proinflammatory mediators C3a and C5a are essential for liver regeneration
CW Strey, M Markiewski, D Mastellos, R Tudoran, LA Spruce, LE Greenbaum, JD Lambris
Journal of Experimental Medicine 2003
CCAAT/enhancer-binding protein beta is required for mitotic clonal expansion during adipogenesis
QQ Tang, TC Otto, MD Lane
Proceedings of the National Academy of Sciences 2003
Expression and DNA-binding activity of signal transducer and activator of transcription 3 in alcoholic cirrhosis compared to normal liver and primary biliary cirrhosis in humans
P Stärkel, K Bishop, Y Horsmans, AJ Strain
The American Journal of Pathology 2003
Liver regeneration
LG Koniaris, IH McKillop, SI Schwartz, TA Zimmers
Journal of the American College of Surgeons 2003
The molecular physiology of liver regeneration following partial hepatectomy
D Mangnall, NC Bird, AW Majeed
Liver International 2003
Entamoeba histolytica: expression and DNA binding of CCAAT/enhancer-binding proteins are regulated through the cell cycle
LA Marchat, M Pezet-Valdez, C López-Camarillo, E Orozco
Experimental Parasitology 2003
Role for growth factors and extracellular matrix in controlling differentiation of prospectively isolated hepatic stem cells
A Suzuki, A Iwama, H Miyashita, H Nakauchi, H Taniguchi
Development (Cambridge, England) 2003
Opposing Roles of C/EBPβ and AP-1 in the Control of Fibroblast Proliferation and Growth Arrest-specific Gene Expression
M Gagliardi, S Maynard, T Miyake, N Rodrigues, SL Tjew, E Cabannes, PA Bédard
The Journal of biological chemistry 2003
Hepatocyte growth factor activates CCAAT enhancer binding protein and cell replication via PI3-kinase pathway
M Cho
Hepatology 2003
Transcription factors in liver development, differentiation, and regeneration
RH Costa, VV Kalinichenko, AX Holterman, X Wang
Hepatology 2003
Signal transduction in the liver: C/EBPβ modulates cell proliferation and survival
M Buck
Hepatology 2003
Making the liver young again
S Mackey, P Singh, GJ Darlington
Hepatology 2003
Impaired Hepatocyte DNA Synthetic Response Posthepatectomy in Insulin-Like Growth Factor Binding Protein 1-Deficient Mice with Defects in C/EBPβ and Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Regulation
JI Leu, MA Crissey, LE Craig, R Taub
Molecular and cellular biology 2003
The role of C/EBPbeta in mammary gland development and breast cancer.
Grimm SL, Rosen JM
Journal of Mammary Gland Biology and Neoplasia 2003
Nitric oxide in liver inflammation and regeneration
Paloma Martin-Sanz, Sonsoles Hortelano, Nuria A Callejas, Nora Goren, Marta Casado, Miriam Zeini, Lisardo Boscá
Metabolic Brain Disease 2002
CCAAT/enhancer-binding proteins: structure, function and regulation
DP Ramji, P Foka
Biochemical Journal 2002
Cholestasis induces murine hepatocyte apoptosis and DNA synthesis with preservation of the immediate-early gene response
MA Bird, PA Lange, LW Schrum, JW Grisham, RA Rippe, KE Behrns
Surgery 2002
CCAAT/enhancer binding proteins in normal mammary development and breast cancer
CA Zahnow
Breast Cancer Research 2002
Inhibited Activities in CCAAT/Enhancer-Binding Protein, Activating Protein-1 and Cyclins after Hepatectomy in Rats with Thioacetamide-Induced Liver Cirrhosis
G Zhao, K Nakano, K Chijiiwa, J Ueda, M Tanaka
Biochemical and Biophysical Research Communications 2002
New dopamine D2 receptor polymorphisms in rats and association with apomorphine-induced stereotypies
S Germeyer, A Birke, U Schmitt, N Dahmen, C Hiemke, U Havemann-Reinecke
Brain Research 2002
Hepatocytes and Endothelial Cells: Joining Forces to Conquer Development
JA Bezerra
Pediatric Research 2002
CCAAT/enhancer binding proteins in normal mammary development and breast cancer
CA Zahnow
Breast Cancer Research 2002
Regulation of CCAAT/Enhancer-binding Protein (C/EBP) Activator Proteins by Heterodimerization with C/EBPγ (Ig/EBP)
SE Parkin, M Baer, TD Copeland, RC Schwartz, PF Johnson
The Journal of biological chemistry 2002
STAT3 Contributes to the Mitogenic Response of Hepatocytes during Liver Regeneration
W Li, X Liang, C Kellendonk, V Poli, R Taub
The Journal of biological chemistry 2002
Independent and overlapping transcriptional activation during liver development and regeneration in mice
N Kelley-Loughnane
Hepatology 2002
Delayed liver regeneration in peroxisome proliferator-activated receptor-α-null mice
S Anderson
Hepatology 2002
The mystery of liver regeneration
FG Court, SA Wemyss-Holden, AR Dennison, GJ Maddern
The British journal of surgery 2002
Impact of cell swelling on proliferative signal transduction in the liver
RD Kim, GS Stein, RS Chari
Journal of Cellular Biochemistry 2001
Nuclear export of phosphorylated C/EBPbeta mediates the inhibition of albumin expression by TNF-alpha
M Buck, L Zhang, NA Halasz, T Hunter, M Chojkier
The EMBO Journal 2001
Prostaglandins are required for CREB activation and cellular proliferation during liver regeneration
DA Rudnick, DH Perlmutter, LJ Muglia
Proceedings of the National Academy of Sciences 2001
After portal branch ligation in the rat, cellular proliferation is associated with selective induction of c-Ha-ras, p53, cyclin E, and Cdk2
P Stärkel, L Lambotte, C Sempoux, CD Saeger, A Saliez, D Maiter, Y Horsmans
Gut 2001
Plasminogen activators direct reorganization of the liver lobule after acute injury
JA Bezerra, AR Currier, H Melin-Aldana, G Sabla, TH Bugge, KW Kombrinck, JL Degen
The American Journal of Pathology 2001
Lower Activity of CCAAT/Enhancer-Binding Protein and Expression of Cyclin E, but Not Cyclin D1, Activating Protein-1 and p21WAF1, after Partial Hepatectomy in Obstructive Jaundice
K Nakano, K Chijiiwa, M Tanaka
Biochemical and Biophysical Research Communications 2001
Expression of CCAAT/Enhancer Binding Protein Family Genes in Monolayer and Sandwich Culture of Hepatocytes: Induction of Stress-Inducible GADD153
RC Wilkinson, AJ Dickson
Biochemical and Biophysical Research Communications 2001
Expression and function of CCAAT/enhancer binding protein? (C/EBP?) LAP and LIP isoforms in mouse mammary gland, tumors and cultured mammary epithelial cells
LR Dearth, J Hutt, A Sattler, A Gigliotti, J DeWille
Journal of Cellular Biochemistry 2001
The chum salmon insulin-like growth factor II promoter requires Sp1 for its activation by C/EBPβ
AY Palamarchuk, VM Kavsan, JS Sussenbach, PE Holthuizen
Molecular and Cellular Endocrinology 2001
Expression and DNA-binding activity of C/EBPα and C/EBPβ in human liver and differentiated primary hepatocytes
JB Ferrini, E Rodrigues, V Dulic, L Pichard-Garcia, JM Fabre, P Blanc, P Maurel
Journal of Hepatology 2001
Ras adenoviruses modulate cyclin E protein expression and DNA synthesis after partial hepatectomy
T Lüdde, S Kubicka, J Plümpe, C Liedtke, MP Manns, C Trautwein
Oncogene 2001
Epidermal growth factor induces Egr-1 promoter activity in hepatocytes in vitro and in vivo
JC Tsai, L Liu, J Zhang, KC Spokes, JN Topper, WC Aird
AJP Gastrointestinal and Liver Physiology 2001
Regulated Nuclear-Cytoplasmic Localization of CCAAT/ Enhancer-binding Protein δ in Osteoblasts
J Billiard, Y Umayahara, K Wiren, M Centrella, TL McCarthy, P Rotwein
The Journal of biological chemistry 2001
Enhanced proliferation and differentiation of rat hepatocytes cultured with bone marrow stromal cells
T Mizuguchi, T Hui, K Palm, N Sugiyama, T Mitaka, AA Demetriou, J Rozga
Journal of Cellular Physiology 2001
Characterization of C/EBP? isoforms in normal versus neoplastic mammary epithelial cells
EM Eaton, M Hanlon, L Bundy, L Sealy
Journal of Cellular Physiology 2001
Liver regeneration: From laboratory to clinic
N Fausto
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2001
Compensatory hepatic regeneration after mild, but not fulminant, intraperitoneal sepsis in rats
YG Weiss, L Bellin, PK Kim, KM Andrejko, CA Haaxma, N Raj, EE Furth, CS Deutschman
AJP Gastrointestinal and Liver Physiology 2001
The constitutive activation of the CEF-4/9E3 chemokine gene depends on C/EBPβ in v-src transformed chicken embryo fibroblasts
M Gagliardi, S Maynard, B Bojovic, PA Bédard
Oncogene 2001
Contribution of cyclooxygenase‐2 to liver regeneration after partial hepatectomy
M Casado, NA Callejas, J Rodrigo, X Zhao, SK Dey, L Boscá, P MartínSanz
The FASEB Journal 2001
Cytokine-Responsive Gene-2/IFN-Inducible Protein-10 Expression in Multiple Models of Liver and Bile Duct Injury Suggests a Role in Tissue Regeneration
LG Koniaris, T Zimmers-Koniaris, EC Hsiao, K Chavin, JV Sitzmann, JM Farber
Journal of immunology (Baltimore, Md. : 1950) 2001
Interleukin 6 and liver regeneration
KL Streetz, T Luedde, MP Manns, C Trautwein
Gut 2000
Role of C/EBP homologous protein (CHOP-10) in the programmed activation of CCAAT/enhancer-binding protein-beta during adipogenesis
QQ Tang, MD Lane
Proceedings of the National Academy of Sciences 2000
Increased toxin-induced liver injury and fibrosis in interleukin-6-deficient mice
K Kovalovich, RA DeAngelis, W Li, EE Furth, G Ciliberto, R Taub
Hepatology 2000
The Egr-1 promoter contains information for constitutive and inducible expression in transgenic mice
JC Tsai, L Liu, BC Cooley, MR DiChiara, JN Topper, WC Aird
The FASEB Journal 2000
Regulation of cyclooxygenase 2 expression in hepatocytes by CCAAT/enhancer-binding proteins
NA Callejas, L Boscá, CS Williams, RN DuBois, P Martín-Sanz
Gastroenterology 2000
The Hepatocyte Review
MN Berry, AM Edwards
2000
Translational Induction of Liver-enriched Transcriptional Inhibitory Protein during Acute Phase Response Leads to Repression of CCAAT/Enhancer Binding Protein α mRNA
AL Welm, SL Mackey, LT Timchenko, GJ Darlington, NA Timchenko
The Journal of biological chemistry 2000
Hypoglycemia and impaired hepatic glucose production in mice with a deletion of the C/EBPβ gene
S Liu, C Croniger, C Arizmendi, M Harada-Shiba, J Ren, V Poli, RW Hanson, JE Friedman
Journal of Clinical Investigation 1999
Phosphorylation of Rat Serine 105 or Mouse Threonine 217 in C/EBPβ Is Required for Hepatocyte Proliferation Induced by TGFα
M Buck, V Poli, P der Geer, M Chojkier, T Hunter
Molecular Cell 1999
Cellular and molecular biology of the liver
SJ Karpen, JM Crawford
Current Opinion in Gastroenterology 1999
Plasminogen deficiency leads to impaired remodeling after a toxic injury to the liver
JA Bezerra, TH Bugge, H Melin-Aldana, G Sabla, KW Kombrinck, DP Witte, JL Degen
Proceedings of the National Academy of Sciences 1999
Premature expression of the winged helix transcription factor HFH-11B in regenerating mouse liver accelerates hepatocyte entry into S phase
H Ye, AX Holterman, KW Yoo, RR Franks, RH Costa
Molecular and cellular biology 1999
Lipopolysaccharide potentiates the effect of hepatocyte growth factor on hepatocyte replication in rats by augmenting AP-1 activity
C Gao, R Jokerst, P Gondipalli, SR Cai, S Kennedy, MW Flye, KP Ponder
Hepatology 1999
Molecular mechanisms of liver development and differentiation
G Darlington
Current Opinion in Cell Biology 1999
The Relationship between Differentiation and Proliferation in Late Gestation Fetal Rat Hepatocytes
PA Gruppuso, TC Bienieki, RA Faris
Pediatric Research 1999
CUG repeat binding protein (CUGBP1) interacts with the 5' region of C/EBP  mRNA and regulates translation of C/EBP  isoforms
NA Timchenko, AL Lu, X Welm, LT Timchenko
Nucleic Acids Research 1999
Ethanol rapidly inhibits IL-6-activated STAT3 and C/EBP mRNA expression in freshly isolated rat hepatocytes
J Chen, G Kunos, B Gao
FEBS Letters 1999
CCAAT/Enhancer-binding Protein δ Is a Critical Regulator of Insulin-like Growth Factor-I Gene Transcription in Osteoblasts
Y Umayahara, J Billiard, C Ji, M Centrella, TL McCarthy, P Rotwein
The Journal of biological chemistry 1999
V. Knocking out genes to study liver regeneration: present and future
N Fausto
AJP Gastrointestinal and Liver Physiology 1999
C/EBPα Regulates Generation of C/EBPβ Isoforms through Activation of Specific Proteolytic Cleavage
AL Welm, NA Timchenko, GJ Darlington
Molecular and cellular biology 1999
Transcriptional Up-regulation of the Delayed Early Gene HRS/SRp40 during Liver Regeneration: INTERACTIONS AMONG YY1, GA-BINDING PROTEINS, AND MITOGENIC SIGNALS
K Du, JI Leu, Y Peng, R Taub
The Journal of biological chemistry 1998

← Previous 1 2 3 … 9 10 Next →

Advertisement

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts

Referenced in 2 patents
60 readers on Mendeley
See more details