Citations to this article

Synoviocyte-packaged Chlamydia trachomatis induces a chronic aseptic arthritis.
R D Inman, B Chiu
R D Inman, B Chiu
Published November 15, 1998
Citation Information: J Clin Invest. 1998;102(10):1776-1782. https://doi.org/10.1172/JCI2983.
View: Text | PDF
Research Article

Synoviocyte-packaged Chlamydia trachomatis induces a chronic aseptic arthritis.

Abstract

The basic mechanisms underlying reactive arthritis and specifically the joint injury that follows intra-articular Chlamydia trachomatis infection have not been defined. The present study addresses this question through the development of an experimental model. Stable cell lines were generated from synoviocytes harvested from the knee joints of Lewis rats. The synoviocytes were cocultivated with C. trachomatis to allow invasion by the microbe and were then transferred by intra-articular injection into the knee joints of Lewis rats. The ensuing arthritis could be subdivided into an early phase (

Authors

R D Inman, B Chiu

×

Total citations by year

Year: 2020 2019 2015 2014 2012 2011 2010 2009 2006 2005 2004 2002 2001 2000 1999 1991 Total
Citations: 1 1 1 1 1 1 2 2 1 1 3 4 2 3 2 1 27
Citation information

Citations to this article (27)

Title and authors Publication Year
Chlamydia pecorum –Induced Arthritis in Experimentally and Naturally Infected Sheep
N Ostfeld, MM Islam, M Jelocnik, M Hilbe, T Sydler, S Hartnack, C Jacobson, T Clune, I Marsh, N Sales, A Polkinghorne, N Borel 		Veterinary pathology 2020
The Importance of HLA-B27 in the Evolution of Reactive Arthritis
S Bănicioiu-Covei, A F Vreju, A Rosu, P L Ciurea 		Current Health Sciences Journal 2019
Rho GTPases as pathogen targets: Focus on curable sexually transmitted infections
CA Quintero, JG Tudela, MT Damiani 		Small GTPases 2015
The role of intracellular organisms in the pathogenesis of inflammatory arthritis
A Singh, S Karrar 		International Journal of Inflammation 2014
Nafamostat mesylate, a serine protease inhibitor, demonstrates novel antimicrobial properties and effectiveness in Chlamydia-induced arthritis
RD Inman, B Chiu 		Arthritis Research & Therapy 2012
Sexually Transmitted Infections and Sexually Transmitted Diseases
GE Gross, SK Tyring 		2011
Is the role of Chlamydia trachomatis underestimated in patients with suspected reactive arthritis?
MB OWLIA, AR ELEY 		International Journal of Rheumatic Diseases 2010
Bone Marrow-derived Human Hematopoietic Stem Cells Engraft NOD/SCID Mice and Traffic Appropriately to an Inflammatory Stimulus in the Joint
NH Chang, RD Inman, JE Dick, JE Wither 		The Journal of rheumatology 2010
Heavy metal exposure reverses genetic resistance to Chlamydia-induced arthritis
RD Inman, B Chiu 		Arthritis Research & Therapy 2009
Molecular Mechanisms of Spondyloarthropathies
C López-Larrea, R Díaz-Peña 		2009
Early cytokine profiles in the joint define pathogen clearance and severity of arthritis inChlamydia-induced arthritis in rats
RD Inman, B Chiu 		Arthritis & Rheumatism 2006
Innate immunity and arthritis: neutrophil rac and toll-like receptor 4 expression define outcomes in infection-triggered arthritis
Xiang Zhang, Michael Glogauer, Fei Zhu, Tae-Hwan Kim, Basil Chiu, Robert D. Inman 		Arthritis & Rheumatism 2005
Synovial Fibroblasts Infected with Salmonella enterica Serovar Typhimurium Mediate Osteoclast Differentiation and Activation
X Zhang, JE Aubin, TH Kim, U Payne, B Chiu, RD Inman 		Infection and immunity 2004
Reactive Arthritis
SG Childs 		Orthopaedic Nursing 2004
Infection and Autoimmunity
C Dugué, Y Renaudineau, P Youinou 		Infection and Autoimmunity 2004
Reactive arthritis or chronic infectious arthritis?
J Sibilia, FX Limbach 		Annals of the rheumatic diseases 2002
Chlamydial conjunctivitis (in adults), uveitis, and reactive arthritis, including SARA
EM Haller-Schober, Y El-Shabrawi 		Best Practice & Research Clinical Obstetrics & Gynaecology 2002
Breakdown of CTL tolerance to self HLA-B*2705 induced by exposure to Chlamydia trachomatis
I Popov, CS Cruz, BH Barber, B Chiu, RD Inman 		Journal of immunology (Baltimore, Md. : 1950) 2002
Role of Interferon-Stimulated Gene Factor 3γ and Beta Interferon in HLA Class I Enhancement in Synovial Fibroblasts upon Infection with Chlamydia trachomatis
J Rödel, H Vogelsang, K Prager, M Hartmann, KH Schmidt, E Straube 		Infection and immunity 2002
The reprogrammed host:Chlamydia trachomatis-induced up-regulation of glycoprotein 130 cytokines, transcription factors, and antiapoptotic genes
S Hess, C Rheinheimer, F Tidow, G Bartling, C Kaps, J Lauber, J Buer, A Klos 		Arthritis & Rheumatism 2001
The Effect of an Anti-HLA-B27 Immune Response on CTL Recognition of Chlamydia
I Popov, CS Cruz, BH Barber, B Chiu, RD Inman 		Journal of immunology (Baltimore, Md. : 1950) 2001
Animal models of the spondyloarthropathies
M Breban, G Falgarone, H Blanchard, E Dernis-Labous, D Lamarque 		Current Rheumatology Reports 2000
Chlamydia and associated arthritis:
RD Inman, JA Whittum-Hudson, HR Schumacher, AP Hudson 		Current Opinion in Rheumatology 2000
Persistence of Chlamydia trachomatis Is Induced by Ciprofloxacin and Ofloxacin In Vitro
U Dreses-Werringloer, I Padubrin, B Jürgens-Saathoff, AP Hudson, H Zeidler, L Köhler 		Antimicrobial agents and chemotherapy 2000
Reactive arthritis:
J Sieper, J Braun 		Current Opinion in Rheumatology 1999
Reactive Arthritis. Reaktive Arthritis
J Braun, J Sieper 		LaboratoriumsMedizin 1999
Rheumatology
RA Asherson, R Cervera, DP D'Cruz, GR Hughes 		Postgraduate medical journal 1991

Advertisement