JCI - Citations to Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells

Citations to this article

Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells

Jens Dannull, … , Eli Gilboa, Johannes Vieweg

Jens Dannull, … , Eli Gilboa, Johannes Vieweg

Published December 1, 2005
Citation Information: J Clin Invest. 2005;115(12):3623-3633. https://doi.org/10.1172/JCI25947.

View: Text | PDF

Research Article Immunology

Total citations by year

Year:	2025	2024	2023	2022	2021	2020	2019	2018	2017	2016	2015	2014	2013	2012	2011	2010	2009	2008	2007	2006	Total
Citations:	2	5	4	7	8	9	8	17	17	7	13	23	30	33	34	38	38	40	30	14	377

Citation information

Citations to this article (377)

Title and authors	Publication	Year
A Phase II Study of Denileukin Diftitox in Patients with Advanced Treatment Refractory Breast Cancer Gwin WR III, Salazar LG, Dai JY, Higgins D, Coveler AL, Childs JS, Blancas R, Dang Y, Reichow J, Slota M, Lu H, Disis ML	Vaccines	2025
Regulatory T cells in the tumour microenvironment. Imianowski CJ, Chen Q, Workman CJ, Vignali DAA	Nature reviews. Cancer	2025
Tumor microenvironment reprogramming by nanomedicine to enhance the effect of tumor immunotherapy Huang Y, Fan H, Ti H	Asian Journal of Pharmaceutical Sciences	2024
Cancer mRNA vaccines: clinical advances and future opportunities. Sayour EJ, Boczkowski D, Mitchell DA, Nair SK	Nature reviews. Clinical oncology	2024
SIRPG promotes lung squamous cell carcinoma pathogenesis via M1 macrophages: a multi-omics study integrating data and Mendelian randomization Mao G, Li J, Wang N, Yu H, Han S, Xiang M, Zhang H, Zeng D, Jiang J, Ma H	Frontiers in Oncology	2024
Peripheral-derived regulatory T cells contribute to tumor-mediated immune suppression in a nonredundant manner Hossain MM, King P, Hackett J, Gerard HC, Niwinski R, Wu L, Van Kaer L, Dyson G, Gibson H, Borowsky AD, Sebzda E	Proceedings of the National Academy of Sciences of the United States of America	2024
Improving the efficacy of immunotherapy for colorectal cancer: Targeting tumor microenvironment-associated immunosuppressive cells Zou D, Xin X, Xu Y, Xu H, Huang L, Xu T	Heliyon	2024
RNA modification in mRNA cancer vaccines Mei Y, Wang X	Clinical and Experimental Medicine	2023
CD4+CD25+ regulatory T cells decreased future liver remnant after associating liver partition and portal vein ligation for staged hepatectomy Wang W, Ye CH, Deng ZF, Wang JL, Zhang L, Bao L, Xu BH, Zhu H, Guo Y, Wen Z	World journal of gastrointestinal surgery	2023
The prognostic and biology of tumour-infiltrating lymphocytes in the immunotherapy of cancer. Liu Y, Liu Z, Yang Y, Cui J, Sun J, Liu Y	British Journal of Cancer	2023
Lung tumor–infiltrating Treg have divergent transcriptional profiles and function linked to checkpoint blockade response Dykema AG, Zhang J, Cheung LS, Connor S, Zhang B, Zeng Z, Cherry CM, Li T, Caushi JX, Nishimoto M, Munoz AJ, Ji Z, Hou W, Zhan W, Singh D, Zhang T, Rashid R, Mitchell-Flack M, Bom S, Tam A, Ionta N, Aye TH, Wang Y, Sawosik CA, Tirado LE, Tomasovic LM, VanDyke D, Spangler JB, Anagnostou V, Yang S, Spicer J, Rayes R, Taube J, Brahmer JR, Forde PM, Yegnasubramanian S, Ji H, Pardoll DM, Smith KN	Science Immunology	2023
T Cell Memory in Infection, Cancer, and Autoimmunity. Barnaba V	Frontiers in immunology	2022
Cancer vaccines: the next immunotherapy frontier. Lin MJ, Svensson-Arvelund J, Lubitz GS, Marabelle A, Melero I, Brown BD, Brody JD		2022
Tobacco Use and Response to Immune Checkpoint Inhibitor Therapy in Non-Small Cell Lung Cancer. Corke LK, Li JJN, Leighl NB, Eng L	Current oncology (Toronto, Ont.)	2022
Boosting the Immune Response—Combining Local and Immune Therapy for Prostate Cancer Treatment Karwacki J, Kiełbik A, Szlasa W, Sauer N, Kowalczyk K, Krajewski W, Saczko J, Kulbacka J, Szydełko T, Małkiewicz B	Cells	2022
Therapeutic targeting of regulatory T cells in cancer. Shan F, Somasundaram A, Bruno TC, Workman CJ, Vignali DAA	Trends in Cancer	2022
Inhibition of FOXP3 by stapled alpha-helical peptides dampens regulatory T cell function Hawley KM, Eclov RJ, Schnorenberg MR, Tian Y, Shah RN, Thomas-Toth AT, Fefferman M, Bird GH, Walensky LD, Tirrell MV, LaBelle JL	Proceedings of the National Academy of Sciences	2022
The Current and Future Promises of Combination Radiation and Immunotherapy for Genitourinary Cancers Saidian A, Dolendo I, Sharabi A, Stewart TF, Rose B, McKay RR, Bagrodia A, Salmasi A	Cancers	2022
Inflammation and tumor progression: signaling pathways and targeted intervention H Zhao, L Wu, G Yan, Y Chen, M Zhou, Y Wu, Y Li	Signal Transduction and Targeted Therapy	2021
The Therapeutic Potential of Regulatory T Cells: Challenges and Opportunities F Bayati, M Mohammadi, M Valadi, S Jamshidi, AM Foma, E Sharif-Paghaleh	Frontiers in immunology	2021
A Novel CAR Expressing NK Cell Targeting CD25 With the Prospect of Overcoming Immune Escape Mechanism in Cancers M Dehbashi, Z Hojati, M Motovali-bashi, MR Ganjalikhany, WC Cho, A Shimosaka, P Navabi, M Ganjalikhani-Hakemi	Frontiers in Oncology	2021
An Overview on the Development of mRNA-Based Vaccines and Their Formulation Strategies for Improved Antigen Expression In Vivo M Rahman, N Zhou, J Huang	Human vaccines	2021
Functional Ambivalence of Dendritic Cells: Tolerogenicity and Immunogenicity JH Nam, JH Lee, SY Choi, NC Jung, JY Song, HG Seo, DS Lim	International journal of molecular sciences	2021
Therapeutic melanoma inhibition by local micelle-mediated cyclic nucleotide repression K Johann, T Bohn, F Shahneh, N Luther, A Birke, H Jaurich, M Helm, M Klein, VK Raker, T Bopp, M Barz, C Becker	Nature Communications	2021
The Role of Post-Translational Modifications of Chemokines by CD26 in Cancer AD Zutter, JV Damme, S Struyf	Cancers	2021
Bacteria‐Based Cancer Immunotherapy X Huang, J Pan, F Xu, B Shao, Y Wang, X Guo, S Zhou	Advanced Science	2021
IRF4 instructs effector Treg differentiation and immune suppression in human cancer Giorgia Alvisi, Jolanda Brummelman, Simone Puccio, Emilia Maria Cristina Mazza, Elisa Paoluzzi Tomada, Agnese Losurdo, Veronica Zanon, Clelia Peano, Federico S. Colombo, Alice Scarpa, Marco Alloisio, Ajithkumar Vasanthakumar, Rahul Roychoudhuri, Marinos Kallikourdis, Massimiliano Pagani, Egesta Lopci, Pierluigi Novellis, Jonas Blume, Axel Kallies, Giulia Veronesi, Enrico Lugli	Journal of Clinical Investigation	2020
Antitumor efficacy of combined CTLA4/PD-1 blockade without intestinal inflammation is achieved by elimination of FcγR interactions D Bauché, S Mauze, C Kochel, J Grein, A Sawant, Y Zybina, W Blumenschein, P Yang, L Annamalai, JH Yearley, J Punnonen, EP Bowman, A Chackerian, D Laface	Journal for ImmunoTherapy of Cancer	2020
Long noncoding RNA: a dazzling dancer in tumor immune microenvironment Y Zhang, Q Liu, Q Liao	Journal of Experimental & Clinical Cancer Research	2020
Long noncoding RNA loss in immune suppression in cancer Q Hu, SD Egranov, C Lin, L Yang	Pharmacology & Therapeutics	2020
Therapeutic Cancer Vaccination with Ex Vivo RNA-Transfected Dendritic Cells—An Update J Dörrie, N Schaft, G Schuler, B Schuler-Thurner	Pharmaceutics	2020
Harnessing the Complete Repertoire of Conventional Dendritic Cell Functions for Cancer Immunotherapy L Amon, L Hatscher, L Heger, D Dudziak, CH Lehmann	Pharmaceutics	2020
Relevance of Regulatory T Cells during Colorectal Cancer Development JE Olguín, I Medina-Andrade, T Rodríguez, M Rodríguez-Sosa, LI Terrazas	Cancers	2020
Ribonucleic Acid Engineering of Dendritic Cells for Therapeutic Vaccination: Ready ‘N Able to Improve Clinical Outcome? Y Willemen, M Versteven, M Peeters, ZN Berneman, EL Smits	Cancers	2020
Extracellular vesicles produced by immunomodulatory cells harboring OX40 ligand and 4-1BB ligand enhance antitumor immunity IF Semionatto, S Palameta, JM Toscaro, AJ Manrique-Rincón, LP Ruas, AF Leme, MC Bajgelman	Scientific Reports	2020
Recent advances with Treg depleting fusion protein toxins for cancer immunotherapy P Kumar, A Kumar, S Parveen, JR Murphy, W Bishai	Immunotherapy	2019
Immune and Inflammatory Cells in Thyroid Cancer Microenvironment Ferrari, Fallahi, Galdiero, Ruffilli, Elia, Ragusa, Paparo, Patrizio, Mazzi, Varricchi, Marone, Antonelli	International journal of molecular sciences	2019
Anti-regulatory T cell vaccines in immunotherapy: focusing on FoxP3 as target NM Niri, M Naseroleslami, J Hadjati	Human Vaccines & Immunotherapeutics	2019
Zoledronic acid blocks the interaction between breast cancer cells and regulatory T-cells H Liu, SH Wang, SC Chen, CY Chen, TM Lin	BMC Cancer	2019
Recent advances in understanding immune phenotypes of thyroid carcinomas: prognostication and emerging therapies F Liotti, N Prevete, G Vecchio, RM Melillo	F1000Research	2019
Turning the Tide Against Regulatory T Cells SJ Han, A Toker, ZQ Liu, PS Ohashi	Frontiers in Oncology	2019
Depleting T regulatory cells by targeting intracellular Foxp3 with a TCR mimic antibody T Dao, SS Mun, AC Scott, CA Jarvis, T Korontsvit, Z Yang, L Liu, MG Klatt, M Guerreiro, A Selvakumar, EJ Brea, C Oh, C Liu, DA Scheinberg	OncoImmunology	2019
Blocking inflammation to improve immunotherapy of advanced cancer A Macciò, C Madeddu	Immunology	2019
The Long Non-coding RNA Flatr Anticipates Foxp3 Expression in Regulatory T Cells A Brajic, D Franckaert, O Burton, S Bornschein, AL Calvanese, S Demeyer, J Cools, J Dooley, S Schlenner, A Liston	Frontiers in immunology	2018
Tumor Necrosis Factor α and Regulatory T Cells in Oncoimmunology BL Salomon, M Leclerc, J Tosello, E Ronin, E Piaggio, JL Cohen	Frontiers in immunology	2018
Regulatory T cells in the treatment of disease A Sharabi, MG Tsokos, Y Ding, TR Malek, D Klatzmann, GC Tsokos	Nature Reviews Drug Discovery	2018
Folate Receptor Alpha Peptide Vaccine Generates Immunity in Breast and Ovarian Cancer Patients KR Kalli, MS Block, PM Kasi, CL Erskine, TJ Hobday, A Dietz, D Padley, MP Gustafson, B Shreeder, D Puglisi-Knutson, DW Visscher, TK Mangskau, G Wilson, KL Knutson	Clinical cancer research	2018
Latest development on RNA-based drugs and vaccines K Lundstrom	Future Science OA	2018
Prognostic significance of tumor immune microenvironment and immunotherapy: Novel insights and future perspectives in gastric cancer DC Lazăr, MF Avram, I Romoșan, M Cornianu, S Tăban, A Goldiș	World journal of gastroenterology : WJG	2018
The opposing roles of CD4 + T cells in anti-tumour immunity T Ahrends, J Borst	Immunology	2018
T-Cell Immunopeptidomes Reveal Cell Subtype Surface Markers Derived From Intracellular Proteins N Olsson, LM Schultz, L Zhang, MS Khodadoust, R Narayan, DK Czerwinski, R Levy, JE Elias	PROTEOMICS	2018
B and T Cell Phenotypic Profiles of African HIV-Infected and HIV-Exposed Uninfected Infants: Associations with Antibody Responses to the Pentavalent Rotavirus Vaccine A Weinberg, J Lindsey, R Bosch, D Persaud, P Sato, A Ogwu, A Asmelash, M Bwakura-Dangarambezi, BH Chi, J Canniff, S Lockman, S Gaseitsiwe, S Moyo, CE Smith, NO Moraka, MJ Levin	Frontiers in immunology	2018
Current challenges for cancer vaccine adjuvant development WS Bowen, AK Svrivastava, L Batra, H Barsoumian, H Shirwan	Expert Review of Vaccines	2018
Immune consequences of anti-angiogenic therapy in renal cell carcinoma KK Brodaczewska, C Szczylik, C Kieda	WSPOLCZESNA ONKOL	2018
Treg Fragility: A Prerequisite for Effective Antitumor Immunity? AE Overacre-Delgoffe, DA Vignali	Cancer immunology research	2018
Inflammation-induced Id2 promotes plasticity in regulatory T cells SM Hwang, G Sharma, R Verma, S Byun, D Rudra, SH Im	Nature Communications	2018
Effects of tumor metabolic microenvironment on regulatory T cells Y Wang, XL Li, YZ Mo, CM Fan, L Tang, F Xiong, C Guo, B Xiang, M Zhou, J Ma, , X Wu, Y Li, GY Li, Z Zeng, W Xiong	Molecular Cancer	2018
A TOP2A‑derived cancer panel drives cancer progression in papillary renal cell carcinoma M Ye, Z He, W Dai, Z Li, X Chen, J Liu	Oncology Letters	2018
IL-33 Promotes the Development of Colorectal Cancer Through Inducing Tumor-Infiltrating ST2L + Regulatory T Cells in Mice Y Zhou, Y Ji, H Wang, H Zhang, H Zhou	Technology in cancer research & treatment	2018
Reduction of myeloid-derived suppressor cells reinforces the anti-solid tumor effect of recipient leukocyte infusion in murine neuroblastoma-bearing allogeneic bone marrow chimeras Dierckx de Casterlé I, Fevery S, Rutgeerts O, Poosti F, Struyf S, Lenaerts C, Waer M, Billiau AD, Sprangers B	Cancer Immunology, Immunotherapy	2018
Moesin controls TGF-β signaling and iTregs and attenuation improves adoptive T cell therapy Ephraim Ansa-Addo, Yongliang Zhang, Yi Yang, George Hussey, Breege Howley, Mohammad Salem, Brian Riesenberg, Shaoli Sun, Don Rockey, Serhan Karvar, Philip Howe, Bei Liu, zihai Li	Journal of Clinical Investigation	2017
Requirement of Treg-intrinsic CTLA4-PKCη signaling pathway for suppressing tumor immunity Christophe Pedros, Ann Canonigo-Balancio, Kok-Fai Kong, Amnon Altman	JCI Insight	2017
Combinatorial drug delivery approaches for immunomodulation JM Stewart, BG Keselowsky	Advanced Drug Delivery Reviews	2017
Phenotypic and Functional Properties of Tumor-Infiltrating Regulatory T Cells GR Lee	Mediators of Inflammation	2017
Evaluation of Lactobacillus coryniformis CECT5711 strain as a coadjuvant in a vaccination process: a randomised clinical trial in healthy adults N Redondo, E Nova, A Gheorghe, LE Díaz, A Hernández, A Marcos	Nutrition & Metabolism	2017
Immunogenicity is preferentially induced in sparse dendritic cell cultures A Nasi, VP Bollampalli, M Sun, Y Chen, S Amu, S Nylén, L Eidsmo, AG Rothfuchs, B Réthi	Scientific Reports	2017
Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors FA Vargas, AJ Furness, I Solomon, K Joshi, L Mekkaoui, MH Lesko, EM Rota, R Dahan, A Georgiou, A Sledzinska, AB Aissa, D Franz, MW Sunderland, YN Wong, JY Henry, T OBrien, D Nicol, B Challacombe, SA Beers, S Turajlic, M Gore, J Larkin, C Swanton, KA Chester, M Pule, JV Ravetch, T Marafioti, KS Peggs, SA Quezada, L Spain, A Wotherspoon, N Francis, M Smith, D Strauss, A Hayes, A Soultati, M Stares, L Spain, J Lynch, N Fotiadis, A Fernando, S Hazell, A Chandra, L Pickering, S Rudman, S Chowdhury, C Swanton, M Jamal-Hanjani, S Veeriah, S Shafi, J Czyzewska-Khan, D Johnson, J Laycock, L Bosshard-Carter, G Goh, R Rosenthal, P Gorman, N Murugaesu, RE Hynds, G Wilson, NJ Birkbak, TB Watkins, N McGranahan, S Horswell, R Mitter, M Escudero, A Stewart, PV Loo, A Rowan, H Xu, S Turajlic, C Hiley, C Abbosh, J Goldman, RK Stone, T Denner, N Matthews, G Elgar, S Ward, J Biggs, M Costa, S Begum, B Phillimore, T Chambers, E Nye, S Graca, MA Bakir, JA Hartley, HL Lowe, J Herrero, D Lawrence, M Hayward, N Panagiotopoulos, S Kolvekar, M Falzon, E Borg, C Simeon, G Hector, A Smith, M Aranda, M Novelli, D Oukrif, SM Janes, R Thakrar, M Forster, T Ahmad, SM Lee, D Papadatos-Pastos, D Carnell, R Mendes, J George, N Navani, A Ahmed, M Taylor, J Choudhary, Y Summers, R Califano, P Taylor, R Shah, P Krysiak, K Rammohan, E Fontaine, R Booton, M Evison, P Crosbie, S Moss, F Idries, L Joseph, P Bishop, A Chaturved, AM Quinn, H Doran, A Leek, P Harrison, K Moore, R Waddington, J Novasio, F Blackhall, J Rogan, E Smith, C Dive, J Tugwood, G Brady, DG Rothwell, F Chemi, J Pierce, S Gulati, B Naidu, G Langman, S Trotter, M Bellamy, H Bancroft, A Kerr, S Kadiri, J Webb, G Middleton, M Djearaman, D Fennell, JA Shaw, JL Quesne, D Moore, A Nakas, S Rathinam, W Monteiro, H Marshall, L Nelson, J Bennett, J Riley, L Primrose, L Martinson, G Anand, S Khan, A Amadi, M Nicolson, K Kerr, S Palmer, H Remmen, J Miller, K Buchan, M Chetty, L Gomersall, J Lester, A Edwards, F Morgan, H Adams, H Davies, M Kornaszewska, R Attanoos, S Lock, A Verjee, M MacKenzie, M Wilcox, H Bell, N Iles, A Hackshaw, Y Ngai, S Smith, N Gower, C Ottensmeier, S Chee, B Johnson, A Alzetani, E Shaw, E Lim, PD Sousa, MT Barbosa, A Bowman, S Jorda, A Rice, H Raubenheimer, C Proli, ME Cufari, JC Ronquillo, A Kwayie, H Bhayani, M Hamilton, Y Bakar, N Mensah, L Ambrose, A Devaraj, S Buderi, J Finch, L Azcarate, H Chavan, S Green, H Mashinga, AG Nicholson, K Lau, M Sheaff, P Schmid, J Conibear, V Ezhil, B Ismail, M Irvin-sellers, V Prakash, P Russell, T Light, T Horey, S Danson, J Bury, J Edwards, J Hill, S Matthews, Y Kitsanta, K Suvarna, P Fisher, AD Keerio, M Shackcloth, J Gosney, P Postmus, S Feeney, J Asante-Siaw	Immunity	2017
Cytokine-induced killer cell therapy for modulating regulatory T cells in patients with non-small cell lung cancer B Yu, J Wang, C He, W Wang, J Tang, R Zheng, C Zhou, H Zhang, Z Fu, Q Li, J Xu	Experimental and therapeutic medicine	2017
Exploring Synergy in Combinations of Tumor-Derived Vaccines That Harbor 4-1BBL, OX40L, and GM-CSF AJ Manrique-Rincón, CM Beraldo, JM Toscaro, MC Bajgelman	Frontiers in immunology	2017
Clinical targeting recombinant immunotoxins for cancer therapy M Li, ZS Liu, XL Liu, Q Hui, SY Lu, LL Qu, YS Li, Y Zhou, HL Ren, P Hu	OncoTargets and therapy	2017
Increased serum level of soluble interleukin-2 receptor is associated with a worse response of metastatic clear cell renal cell carcinoma to interferon alpha and sequential VEGF-targeting therapy A Nukui, A Masuda, H Abe, K Arai, KI Yoshida, T Kamai	BMC Cancer	2017
Tumor-infiltrating CD39 + γδTregs Are Novel Immunosuppressive T Cells in Human Colorectal Cancer G Hu, P Wu, P Cheng, Z Zhang, Z Wang, X Yu, X Shao, D Wu, J Ye, T Zhang, X Wang, F Qiu, J Yan, J Huang	OncoImmunology	2017
Blockage of FOXP3 transcription factor dimerization and FOXP3/AML1 interaction inhibits T regulatory cell activity: sequence optimization of a peptide inhibitor T Lozano, M Gorraiz, A Lasarte-Cía, M Ruiz, O Rabal, J Oyarzabal, S Hervás-Stubbs, D Llopiz, P Sarobe, J Prieto, N Casares, JJ Lasarte	Oncotarget	2017
Tumor-infiltrating FoxP3⁺ Tregs predict favorable outcome in colorectal cancer patients: A meta-analysis G Hu, Z Li, S Wang	Oncotarget	2017
Regulatory effects of dexamethasone on NK and T cell immunity L Chen, M Jondal, K Yakimchuk	Inflammopharmacology	2017
FOXP3 + regulatory T cells in normal prostate tissue, postatrophic hyperplasia, prostatic intraepithelial neoplasia, and tumor histological lesions in men with and without prostate cancer S Davidsson, O Andren, AL Ohlson, J Carlsson, SO Andersson, F Giunchi, JR Rider, M Fiorentino	The Prostate	2017
Oxidative stress controls regulatory T cell apoptosis and suppressor activity and PD-L1-blockade resistance in tumor Tomasz, W Wang, J Crespo, H Zhang, W Wang, S Wei, L Zhao, L Vatan, I Shao, W Szeliga, C Lyssiotis, JR Liu, I Kryczek, W Zou	Nature Immunology	2017
Exploiting IL-17-producing CD4+ and CD8+ T cells to improve cancer immunotherapy in the clinic K Majchrzak, MH Nelson, SR Bailey, JS Bowers, XZ Yu, MP Rubinstein, RA Himes, CM Paulos	Cancer Immunology, Immunotherapy	2016
Reciprocal relationship of T regulatory cells and monocytic myeloid-derived suppressor cells in LP-BM5 murine retrovirus-induced immunodeficiency JL Vella, WR Green, MA O'Connor	Journal of General Virology	2016
Utilizing cell-based therapeutics to overcome immune evasion in hematologic malignancies C Sun, G Dotti, B Savoldo	Blood	2016
From cell biology to immunology: Controlling metastatic progression of cancer via microRNA regulatory networks JH Park, E Theodoratou, GA Calin, JI Shin	OncoImmunology	2016
Single dose denileukin diftitox does not enhance vaccine-induced T cell responses or effectively deplete Tregs in advanced melanoma: immune monitoring and clinical results of a randomized phase II trial JJ Luke, Y Zha, K Matijevich, TF Gajewski	Journal for ImmunoTherapy of Cancer	2016
CCL22-specific T Cells: Modulating the immunosuppressive tumor microenvironment E Martinenaite, SM Ahmad, M Hansen, Ö Met, MW Westergaard, SK Larsen, TW Klausen, M Donia, IM Svane, MH Andersen	OncoImmunology	2016
Immune modulation of CD4+CD25+ regulatory T cells by zoledronic acid H Liu, SH Wang, SC Chen, CY Chen, JL Lo, TM Lin	BMC Immunology	2016
Survival with AGS-003, an autologous dendritic cell–based immunotherapy, in combination with sunitinib in unfavorable risk patients with advanced renal cell carcinoma (RCC): Phase 2 study results A Amin, AZ Dudek, TF Logan, RS Lance, JM Holzbeierlein, JJ Knox, VA Master, SK Pal, WH Miller, LI Karsh, IY Tcherepanova, MA DeBenedette, WL Williams, DC Plessinger, CA Nicolette, RA Figlin	Journal for ImmunoTherapy of Cancer	2015
RNA-Based Vaccines in Cancer Immunotherapy MA McNamara, SK Nair, EK Holl	Journal of Immunology Research	2015
Gastric cancer and the epoch of immunotherapy approaches Elena Niccolai, Antonio Taddei, Antonio Taddei, Domenico Prisco, Domenico Prisco, Amedeo Amedei, Amedeo Amedei	World Journal of Gastroenterology	2015
Intratumoral Myeloid Cells Regulate Responsiveness and Resistance to Antiangiogenic Therapy LB Rivera, D Meyronet, V Hervieu, MJ Frederick, E Bergsland, G Bergers	Cell Reports	2015
Aspartate-β-hydroxylase induces epitope-specific T cell responses in hepatocellular carcinoma Y Tomimaru, S Mishra, H Safran, KP Charpentier, W Martin, AS de Groot, SH Gregory, JR Wands	Vaccine	2015
Highly clonal regulatory T-cell population in follicular lymphoma – inverse correlation with the diversity of CD8 + T cells X Liu, G Venkataraman, J Lin, K Kiyotani, S Smith, M Montoya, Y Nakamura, J Kline	OncoImmunology	2015
Challenges and future perspectives of T cell immunotherapy in cancer MT de Aquino, A Malhotra, MK Mishra, A Shanker	Immunology Letters	2015
Rationale for a Multimodality Strategy to Enhance the Efficacy of Dendritic Cell-Based Cancer Immunotherapy J Datta, E Berk, JA Cintolo, S Xu, RE Roses, BJ Czerniecki	Frontiers in immunology	2015
Regulatory T lymphocytes and transforming growth factor beta in epithelial ovarian tumors-prognostic significance I Winkler, B Wilczynska, A Bojarska-Junak, M Gogacz, A Adamiak, K Postawski, D Darmochwal-Kolarz, T Rechberger, J Tabarkiewicz	Journal of Ovarian Research	2015
SA-4-1BBL/MPL as a novel immune adjuvant platform to combat cancer AK Srivastava, ES Yolcu, G Dinc, RK Sharma, H Shirwan	OncoImmunology	2015
Regulatory T cells, inherited variation, and clinical outcome in epithelial ovarian cancer KL Knutson, MJ Maurer, CC Preston, KB Moysich, K Goergen, KM Hawthorne, JM Cunningham, K Odunsi, LC Hartmann, KR Kalli, AL Oberg, EL Goode	Cancer Immunology, Immunotherapy	2015
Exploiting natural anti-tumor immunity for metastatic renal cell carcinoma KA Murphy, BR James, Y Guan, DS Torry, A Wilber, TS Griffith	Human Vaccines & Immunotherapeutics	2015
GITR engagement in combination with CTLA-4 blockade completely abrogates immunosuppression mediated by human liver tumor-derived regulatory T cells ex vivo A Pedroza-Gonzalez, G Zhou, SP Singh, PP Boor, Q Pan, D Grunhagen, J Jonge, TC Tran, C Verhoef, JN Ijzermans, HL Janssen, K Biermann, J Kwekkeboom, D Sprengers	OncoImmunology	2015
Epigenetic enzymes are the therapeutic targets for CD4+CD25+/highFoxp3+ regulatory T cells JL Pastrana, Y Shao, V Chernaya, H Wang, XF Yang	Translational Research	2014
Antigen-specific vaccines for cancer treatment M Tagliamonte, A Petrizzo, ML Tornesello, FM Buonaguro, L Buonaguro	Human Vaccines & Immunotherapeutics	2014
Targeting CD8 + T-cell tolerance for cancer immunotherapy SR Jackson, J Yuan, RM Teague	Immunotherapy	2014
Fallen Angels or Risen Apes? A Tale of the Intricate Complexities of Imbalanced Immune Responses in the Pathogenesis and Progression of Immune-Mediated and Viral Cancers BO Ondondo	Frontiers in immunology	2014
Regulatorische T-Zellen und NK-Zellen bei Krebspatienten C Bergmann	HNO	2014
Toll-like receptor 9 agonist enhances anti-tumor immunity and inhibits tumor-associated immunosuppressive cells numbers in a mouse cervical cancer model following recombinant lipoprotein therapy LS Chang, CH Leng, YC Yeh, CC Wu, HW Chen, HM Huang, SJ Liu	Molecular Cancer	2014
The targeting of immunosuppressive mechanisms in hematological malignancies MH Andersen	Leukemia	2014
Antibody-based depletion of Foxp3+ T cells potentiates antitumor immune memory in response to mTOR inhibition HL Kim	OncoImmunology	2014
Prediction of antiviral efficacy in patients with chronic hepatitis C by changes in forkhead box protein 3 levels JB Chang, R Xue, ZX Zhou, YH Feng, WW Dai, J Qiu, YF Yang	Experimental and therapeutic medicine	2014
A novel oxygen carrier "YQ23" suppresses the liver tumor metastasis by decreasing circulating endothelial progenitor cells and regulatory T cells CX Li, BL Wong, CC Ling, YY Ma, Y Shao, W Geng, X Qi, SH Lau, SY Kwok, N Wei, FC Tzang, KT Ng, XB Liu, CM Lo, K Man	BMC Cancer	2014
An increased abundance of tumor-infiltrating regulatory T cells is correlated with the progression and prognosis of pancreatic ductal adenocarcinoma Y Tang, X Xu, S Guo, C Zhang, Y Tang, Y Tian, B Ni, B Lu, H Wang	PloS one	2014
Suppression of immunodominant antitumor and antiviral CD8+ T cell responses by indoleamine 2,3-dioxygenase M Rytelewski, CE Meilleur, MA Yekta, PA Szabo, N Garg, TD Schell, AM Jevnikar, S Sharif, B Singh, SM Haeryfar	PloS one	2014
Pilot study of intratumoral injection of recombinant heat shock protein 70 in the treatment of malignant brain tumors in children MA Shevtsov, AV Kim, KA Samochernych, IV Romanova, BA Margulis, IV Guzhova, IV Yakovenko, AM Ischenko, WA Khachatryan	OncoTargets and therapy	2014
Antigen targeting to dendritic cells combined with transient regulatory T cell inhibition results in long-term tumor regression WW Unger, CT Mayer, S Engels, C Hesse, M Perdicchio, F Puttur, I Streng-Ouwehand, M Litjens, H Kalay, L Berod, T Sparwasser, Y Kooyk	OncoImmunology	2014
Tetramer guided, cell sorter assisted production of clinical grade autologous NY-ESO-1 specific CD8+ T cells SM Pollack, RL Jones, EA Farrar, IP Lai, SM Lee, J Cao, VG Pillarisetty, BL Hoch, A Gullett, M Bleakley, EU Conrad, JF Eary, KC Shibuya, EH Warren, JN Carstens, S Heimfeld, SR Riddell, C Yee	Journal for ImmunoTherapy of Cancer	2014
Tumor-secreted miR-214 induces regulatory T cells: a major link between immune evasion and tumor growth Y Yin, X Cai, X Chen, H Liang, Y Zhang, J Li, Z Wang, X Chen, W Zhang, S Yokoyama, C Wang, L Li, L Li, D Hou, L Dong, T Xu, T Hiroi, F Yang, H Ji, J Zhang, K Zen, CY Zhang	Cell Research	2014
Dendritic Cell Cancer Vaccines: From the Bench to the Bedside T Katz, I Avivi, N Benyamini, J Rosenblatt, D Avigan	Rambam Maimonides Medical Journal	2014
SA-4-1BBL and Monophosphoryl Lipid A Constitute an Efficacious Combination Adjuvant for Cancer Vaccines AK Srivastava, G Dinc, RK Sharma, ES Yolcu, H Zhao, H Shirwan	Cancer research	2014
A Feasibility Study of Cyclophosphamide, Trastuzumab, and an Allogeneic GM-CSF-Secreting Breast Tumor Vaccine for HER2+ Metastatic Breast Cancer G Chen, R Gupta, S Petrik, M Laiko, JM Leatherman, JM Asquith, MM Daphtary, E Garrett-Mayer, NE Davidson, K Hirt, M Berg, JN Uram, T Dauses, J Fetting, EM Duus, S Atay-Rosenthal, X Ye, AC Wolff, V Stearns, EM Jaffee, LA Emens	Cancer immunology research	2014
Blockade of MCP-1/CCR4 signaling-induced recruitment of activated regulatory cells evokes an antitumor immune response in head and neck squamous cell carcinoma W Sun, WJ Li, FQ Wei, TS Wong, WB Lei, XL Zhu, J Li, WP Wen	Oncotarget	2014
Classification of current anticancer immunotherapies Galluzzi L, Vacchelli E, Pedro JM, Buqué A, Senovilla L, Baracco EE, Bloy N, Castoldi F, Abastado JP, Agostinis P, Apte RN, Aranda F, Ayyoub M, Beckhove P, Blay JY, Bracci L, Caignard A, Castelli C, Cavallo F, Celis E, Cerundolo V, Clayton A, Colombo MP, Coussens L, Dhodapkar MV, Eggermont AM, Fearon DT, Fridman WH, Fučíková J, Gabrilovich DI, Galon J, Garg A, Ghiringhelli F, Giaccone G, Gilboa E, Gnjatic S, Hoos A, Hosmalin A, Jäger D, Kalinski P, Kärre K, Kepp O, Kiessling R, Kirkwood JM, Klein E, Knuth A, Lewis CE, Liblau R, Lotze MT, Lugli E, Mach JP, Mattei F, Mavilio D, Melero I, Melief CJ, Mittendorf EA, Moretta L, Odunsi A, Okada H, Palucka AK, Peter ME, Pienta KJ, Porgador A, Prendergast GC, Rabinovich GA, Restifo NP, Rizvi N, Sautès-Fridman C, Schreiber H, Seliger B, Shiku H, Silva-Santos B, Smyth MJ, Speiser DE, Spisek R, Srivastava PK, Talmadge JE, Tartour E, Van Der Burg SH, Van Den Eynde BJ, Vile R, Wagner H, Weber JS, Whiteside TL, Wolchok JD, Zitvogel L, Zou W, Kroemer G	Oncotarget	2014
The TLR7 agonist induces tumor regression both by promoting CD4+T cells proliferation and by reversing T regulatory cell-mediated suppression via dendritic cells Wang C, Zhou Q, Wang X, Wu X, Chen X, Li J, Zhu Z, Liu B, Su L	Oncotarget	2014
Foxp3 expression in T regulatory cells and other cell lineages Devaud C, Darcy PK, Kershaw MH	Cancer Immunology, Immunotherapy	2014
Melanoma Immunotherapy Using Mature Dendritic Cells Expressing the Constitutive Proteasome Jens Dannull, N. Rebecca Haley, Gary Archer, Smita Nair, David Boczkowski, Mark Harper, Nicole De Rosa, Nancy Pickett, Paul Mosca, James Burchette, Maria Selim, Duane Mitchell, John Sampson, Douglas Tyler, Scott Pruitt	Journal of Clinical Investigation	2013
Searching for the Achilles Heel of FOXP3 T Lozano, N Casares, JJ Lasarte	Frontiers in Oncology	2013
Targeting Tregs in Malignant Brain Cancer: Overcoming IDO DA Wainwright, M Dey, A Chang, MS Lesniak	Frontiers in immunology	2013
Interleukin-7 Mediates Selective Expansion of Tumor-redirected Cytotoxic T Lymphocytes (CTLs) without Enhancement of Regulatory T-cell Inhibition SK Perna, D Pagliara, A Mahendravada, H Liu, MK Brenner, B Savoldo, G Dotti	Clinical cancer research	2013
Inhibition of CD4+CD25+ regulatory T cell function and conversion into Th1-like effectors by a Toll-like receptor-activated dendritic cell vaccine MK 4th, S Xu, EH Fitzpatrick, A Sharma, HL Graves, BJ Czerniecki	PloS one	2013
Rapid innate control of antigen abrogates adaptive immunity TP Pembroke, AM Gallimore, A Godkin	Immunology	2013
Up-regulation of proliferative and migratory genes in regulatory T cells from patients with metastatic castration-resistant prostate cancer: Proliferative and migratory genes in Tregs NY Huen, AL Pang, JA Tucker, TL Lee, M Vergati, C Jochems, C Intrivici, V Cereda, WY Chan, OM Rennert, RA Madan, JL Gulley, J Schlom, KY Tsang	International Journal of Cancer	2013
Optimal Management of Metastatic Melanoma: Current Strategies and Future Directions M Batus, S Waheed, C Ruby, L Petersen, SD Bines, HL Kaufman	American Journal of Clinical Dermatology	2013
T-cell tolerance in cancer R Nurieva, J Wang, A Sahoo	Immunotherapy	2013
Combining regulatory T cell depletion and inhibitory receptor blockade improves reactivation of exhausted virus-specific CD8+ T cells and efficiently reduces chronic retroviral loads KK Dietze, G Zelinskyy, J Liu, F Kretzmer, S Schimmer, U Dittmer	PLoS pathogens	2013
Immune-checkpoint blockade and active immunotherapy for glioma BJ Ahn, IF Pollack, H Okada	Cancers	2013
Listeriolysin O as a strong immunogenic molecule for the development of new anti-tumor vaccines R Sun, Y Liu	Human Vaccines & Immunotherapeutics	2013
Depletion of T lymphocytes is correlated with response to temozolomide in melanoma patients TZ Iversen, MK Brimnes, K Nikolajsen, RS Andersen, SR Hadrup, MH Andersen, L Bastholt, IM Svane	OncoImmunology	2013
Clinical evaluation of systemic and local immune responses in cancer: time for integration DW Gutkin, MR Shurin	Cancer Immunology, Immunotherapy	2013
Allogeneic partially HLA-matched dendritic cells pulsed with autologous tumor cell lysate as a vaccine in metastatic renal cell cancer: A clinical phase I/II study A Flörcken, J Kopp, A Lessen, K Movassaghi, A Takvorian, K Jöhrens, M Möbs, C Schönemann, B Sawitzki, K Egerer, B Dörken, A Pezzutto, J Westermann	Human Vaccines & Immunotherapeutics	2013
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans D Sugiyama, H Nishikawa, Y Maeda, M Nishioka, A Tanemura, I Katayama, S Ezoe, Y Kanakura, E Sato, Y Fukumori, J Karbach, E Jager, S Sakaguchi	Proceedings of the National Academy of Sciences	2013
Dendritic cell vaccination in pediatric gliomas: lessons learnt and future perspectives M Eyrich, J Rachor, SC Schreiber, M Wölfl, PG Schlegel	Frontiers in Pediatrics	2013
How numbers, nature, and immune status of foxp3(+) regulatory T-cells shape the early immunological events in tumor development G Darrasse-Jèze, K Podsypanina	Frontiers in immunology	2013
Impact of anti-CD25 monoclonal antibody on dendritic cell-tumor fusion vaccine efficacy in a murine melanoma model C Tan, V Reddy, J Dannull, E Ding, SK Nair, DS Tyler, SK Pruitt, WT Lee	Journal of Translational Medicine	2013
Regulatory T cells in allogeneic stem cell transplantation M Michael, A Shimoni, A Nagler	Clinical & developmental immunology	2013
The Th17/Treg balance and the expression of related cytokines in Uygur cervical cancer patients Z Chen, J Ding, N Pang, R Du, W Meng, Y Zhu, Y Zhang, C Ma, Y Ding	Diagnostic Pathology	2013
Partial depletion of regulatory T cells does not influence the inflammation caused by high dose hemi-body irradiation S Ma, JA Richardson, A Bitmansour, TD Solberg, R Pidikiti, K Song, S Stojadinovic, ES Vitetta, JJ Meyer	PloS one	2013
Influence of tumors on protective anti-tumor immunity and the effects of irradiation GA Foulds, J Radons, M Kreuzer, G Multhoff, AG Pockley	Frontiers in Oncology	2013
Suppression, subversion and escape: the role of regulatory T cells in cancer progression K Oleinika, RJ Nibbs, GJ Graham, AR Fraser	Clinical & Experimental Immunology	2013
Modification of the tumor microenvironment as a novel target of renal cell carcinoma therapeutics JH Finke, PA Rayman, JS Ko, JM Bradley, SJ Gendler, PA Cohen	Cancer journal (Sudbury, Mass.)	2013
FOXP3-specific immunity MH Andersen	OncoImmunology	2013
Higher Frequencies of GARP + CTLA-4 + Foxp3 + T Regulatory Cells and Myeloid-Derived Suppressor Cells in Hepatocellular Carcinoma Patients Are Associated with Impaired T-Cell Functionality S Kalathil, AA Lugade, A Miller, R Iyer, Y Thanavala	Cancer research	2013
mRNA: From a chemical blueprint for protein production to an off-the-shelf therapeutic. Van Lint S, Heirman C, Thielemans K, Breckpot K	Human Vaccines & Immunotherapeutics	2013
Immune evasion in acute myeloid leukemia: current concepts and future directions Teague RM, Kline J	Journal for ImmunoTherapy of Cancer	2013
Self-reactive T cells: suppressing the suppressors Becker JC, thor Straten P, Andersen MH	Cancer Immunology, Immunotherapy	2013
Differential effects of Denileukin Diftitox IL-2 immunotoxin on NK and regulatory T cells in non-human primates Y Yamada, A Aoyama, G Tocco, S Boskovic, O Nadazdin, A Alessandrini, JC Madsen, AB Cosimi, G Benichou, T Kawai	Journal of immunology (Baltimore, Md. : 1950)	2012
Cancer stem cell vaccination confers significant anti-tumor immunity N Ning, Q Pan, F Zheng, S Teitz-Tennenbaum, M Egenti, J Yet, M Li, C Ginestier, MS Wicha, JS Moyer, M E.P.Prince, Y Xu, XL Zhang, S Huang, AE Chang, Q Li	Cancer research	2012
Therapeutic opportunities for manipulating TReg cells in autoimmunity and cancer H von Boehmer, C Daniel	Nature Reviews Drug Discovery	2012
The pro-metastatic role of bone marrow-derived cells: a focus on MSCs and regulatory T cells BI Koh, Y Kang	EMBO reports	2012
Targeting Multiple-Myeloma-Induced Immune Dysfunction to Improve Immunotherapy Outcomes S Rutella, F Locatelli	Clinical and Developmental Immunology	2012
Anti-Inflammatory Cytokines: Important Immunoregulatory Factors Contributing to Chemotherapy-Induced Gastrointestinal Mucositis M Sultani, AM Stringer, JM Bowen, RJ Gibson	Chemotherapy Research and Practice	2012
Cancer Immunotherapy TF Gajewski	Molecular Oncology	2012
Lung Cancer: A Classic Example of Tumor Escape and Progression While Providing Opportunities for Immunological Intervention MR Jadus, J Natividad, A Mai, Y Ouyang, N Lambrecht, S Szabo, L Ge, N Hoa, MG Dacosta-Iyer	Clinical and Developmental Immunology	2012
Development of immune memory to glial brain tumors after tumor regression induced by immunotherapeutic Toll-like receptor 7/8 activation A Stathopoulos, C Pretto, L Devillers, D Pierre, FM Hofman, C Kruse, M Jadus, TC Chen, VE Schijns	OncoImmunology	2012
Immunotherapy of cancer in 2012 JM Kirkwood, LH Butterfield, AA Tarhini, H Zarour, P Kalinski, S Ferrone	CA: a cancer journal for clinicians	2012
Regulatory T Cells in Radiotherapeutic Responses D Schaue, MW Xie, JA Ratikan, WH McBride	Frontiers in Oncology	2012
TLR2 ligation protects effector T cells from regulatory T-cell mediated suppression and repolarizes T helper responses following MVA-based cancer immunotherapy L Amiset, L Fend, T Gatard-Scheikl, K Rittner, V Duong, R Rooke, S Muller, JY Bonnefoy, X Preville, H Haegel	OncoImmunology	2012
Regulatory T Cells in Human Ovarian Cancer DJ Peng, R Liu, W Zou	Journal of Oncology	2012
Cytotoxic Chemotherapy and CD4+ Effector T Cells: An Emerging Alliance for Durable Antitumor Effects ZC Ding, G Zhou	Clinical and Developmental Immunology	2012
Cognitive Disorders in Mice: Cytokine Signaling Pathways as Therapeutic Targets A Pukhalsky, G Shmarina, V Alioshkin	Omics A Journal of Integrative Biology	2012
Targeting regulatory T cells C Ménétrier-Caux, T Curiel, J Faget, M Manuel, C Caux, W Zou	Targeted Oncology	2012
Regulatory T cell: a protection for tumour cells Y Wang, Y Ma, Y Fang, S Wu, L Liu, D Fu, X Shen	Journal of Cellular and Molecular Medicine	2012
Leukotriene C4 induces migration of human monocyte-derived dendritic cells without loss of immunostimulatory function J Dannull, T Schneider, WT Lee, N Rosa, DS Tyler, SK Pruitt	Blood	2012
A Pilot Study of IL-2Rα Blockade during Lymphopenia Depletes Regulatory T-cells and Correlates with Enhanced Immunity in Patients with Glioblastoma JH Sampson, RJ Schmittling, GE Archer, KL Congdon, SK Nair, EA Reap, A Desjardins, AH Friedman, HS Friedman, JE 2nd, A Coan, RE McLendon, DA Reardon, JJ Vredenburgh, DD Bigner, DA Mitchell	PloS one	2012
Partial Regulatory T Cell Depletion Prior to Schistosomiasis Vaccination Does Not Enhance the Protection X Wang, F Liu, S Zhou, Z Xu, J Hoellwarth, X Chen, L He, R Zhang, F Liu, J Wang, C Su	PloS one	2012
Class I Histone Deacetylase Inhibitor Entinostat Suppresses Regulatory T Cells and Enhances Immunotherapies in Renal and Prostate Cancer Models L Shen, M Ciesielski, S Ramakrishnan, KM Miles, L Ellis, P Sotomayor, P Shrikant, R Fenstermaker, R Pili	PloS one	2012
Immune Microenvironment in Tumor Progression: Characteristics and Challenges for Therapy V Chew, HC Toh, JP Abastado	Journal of Oncology	2012
Opposing effects of androgen ablation on immune function in prostate cancer S Tang, P Dubey	OncoImmunology	2012
Comparative Antitumor Effect of Preventive versus Therapeutic Vaccines Employing B16 Melanoma Cells Genetically Modified to Express GM-CSF and B7.2 in a Murine Model A Miguel, M Herrero, L Sendra, R Botella, R Algás, M Sánchez, S Aliño	Toxins	2012
Substantially modified ratios of effector to regulatory T cells during chemotherapy in ovarian cancer patients return to pre-treatment levels at completion: implications for immunotherapy A Park, C Govindaraj, SD Xiang, J Halo, M Quinn, K Scalzo-Inguanti, M Plebanski	Cancers	2012
Effects of anticancer agents on cell viability, proliferative activity and cytokine production of peripheral blood mononuclear cells H Sakai, S Kokura, T Ishikawa, R Tsuchiya, M Okajima, T Matsuyama, S Adachi, K Katada, K Kamada, K Uchiyama, O Handa, T Takagi, N Yagi, Y Naito, T Yoshikawa	Journal of Clinical Biochemistry and Nutrition	2012
Blockade of myeloid-derived suppressor cells after induction of lymphopenia improves adoptive T cell therapy in a murine model of melanoma KN Kodumudi, A Weber, AA Sarnaik, S Pilon-Thomas	Journal of immunology (Baltimore, Md. : 1950)	2012
Induction of antitumor immunity ex vivo using dendritic cells transduced with fowl pox vector expressing MUC1, CEA, and a triad of costimulatory molecules (rF-PANVAC) B Vasir, C Zarwan, R Ahmad, KD Crawford, H Rajabi, KI Matsuoka, J Rosenblatt, Z Wu, H Mills, D Kufe, D Avigan	Journal of immunotherapy (Hagerstown, Md. : 1997)	2012
Expansion of effector memory regulatory T cells represents a novel prognostic factor in lower risk myelodysplastic syndrome AW Mailloux, C Sugimori, RS Komrokji, L Yang, JP Maciejewski, MA Sekeres, R Paquette, TP Loughran, AF List, PK Epling-Burnette	Journal of immunology (Baltimore, Md. : 1950)	2012
Tregs in infection and vaccinology: heroes or traitors? L Berod, F Puttur, J Huehn, T Sparwasser	Microbial Biotechnology	2012
Vaccination in the elderly E Derhovanessian, G Pawelec	Microbial Biotechnology	2012
High Immune Response Rates and Decreased Frequencies of Regulatory T Cells in Metastatic Renal Cell Carcinoma Patients after Tumor Cell Vaccination H Pohla, A Buchner, B Stadlbauer, B Frankenberger, S Stevanovic, S Walter, R Frank, T Schwachula, S Olek, J Kopp, G Willimsky, CG Stief, A Hofstetter, A Pezzutto, T Blankenstein, R Oberneder, DJ Schendel	Molecular Medicine	2012
Effects of Chinese Herbal Recipes on Immunity in Immunosuppressive Mice Bao Y, Jing C, Shi W	African Journal of Traditional, Complementary, and Alternative Medicines	2012
Transient depletion of regulatory T cells in transgenic mice reactivates virus-specific CD8+ T cells and reduces chronic retroviral set points KK Dietze, G Zelinskyy, K Gibbert, S Schimmer, S Francois, L Myers, T Sparwasser, KJ Hasenkrug, U Dittmer	Proceedings of the National Academy of Sciences	2011
Distinct roles of CD4+ T cell subpopulations in retroviral immunity: lessons from the Friend virus mouse model S Nair, W Bayer, MJ Ploquin, G Kassiotis, KJ Hasenkrug, U Dittmer	Retrovirology	2011
Dendritic cell based tumor vaccination in prostate and renal cell cancer: a systematic review and meta-analysis A Draube, N Klein-González, S Mattheus, C Brillant, M Hellmich, A Engert, M Bergwelt-Baildon	PloS one	2011
A gynecologic oncology group phase II trial of two p53 peptide vaccine approaches: subcutaneous injection and intravenous pulsed dendritic cells in high recurrence risk ovarian cancer patients OE Rahma, E Ashtar, M Czystowska, ME Szajnik, E Wieckowski, S Bernstein, VE Herrin, MA Shams, SM Steinberg, M Merino, W Gooding, C Visus, AB DeLeo, JK Wolf, JG Bell, JA Berzofsky, TL Whiteside, SN Khleif	Cancer Immunology, Immunotherapy	2011
State of the art in tumor antigen and biomarker discovery K Even-Desrumeaux, D Baty, P Chames	Cancers	2011
Cancer-testis antigen, BORIS based vaccine delivered by dendritic cells is extremely effective against a very aggressive and highly metastatic mouse mammary carcinoma M Mkrtichyan, A Ghochikyan, H Davtyan, N Movsesyan, D Loukinov, V Lobanenkov, DH Cribbs, AK Laust, EL Nelson, MG Agadjanyan	Cellular Immunology	2011
Dendritic cells in cancer immunotherapy: vaccines or autologous transplants? P Kalinski, H Edington, HJ Zeh, H Okada, LH Butterfield, JM Kirkwood, DL Bartlett	Immunologic Research	2011
Allogeneic effector/memory Th-1 cells impair FoxP3+ regulatory T lymphocytes and synergize with chaperone-rich cell lysate vaccine to treat leukemia N Janikashvili, CJ LaCasse, C Larmonier, M Trad, A Herrell, S Bustamante, B Bonnotte, M Har-Noy, N Larmonier, E Katsanis	Blood	2011
Regulatory T Cells in Colorectal Cancer: From Biology to Prognostic Relevance D Mougiakakos	Cancers	2011
Immune suppression in tumors as a surmountable obstacle to clinical efficacy of cancer vaccines G Wieërs, N Demotte, D Godelaine, PV der Bruggen	Cancers	2011
Enhancement of T-cell-mediated antitumor response: angiostatic adjuvant to immunotherapy against cancer RP Dings, KB Vang, K Castermans, F Popescu, Y Zhang, MG Egbrink, MF Mescher, MA Farrar, AW Griffioen, KH Mayo	Clinical cancer research	2011
The Numbers of FoxP3+ Lymphocytes in Sentinel Lymph Nodes of Breast Cancer Patients Correlate With Primary Tumor Size but Not Nodal Status R Gupta, JS Babb, B Singh, L Chiriboga, L Liebes, S Adams, S Demaria	Cancer Investigation	2011
Cancer immunotherapy – revisited WJ Lesterhuis, JB Haanen, CJ Punt	Nature Reviews Drug Discovery	2011
Immunological and Clinical Effects of Vaccines Targeting p53-Overexpressing Malignancies R Vermeij, N Leffers, SH van der Burg, CJ Melief, T Daemen, HW Nijman	Journal of Biomedicine and Biotechnology	2011
Partial regulatory T cell depletion prior to acute feline immunodeficiency virus infection does not alter disease pathogenesis SR Mikkelsen, JM Long, L Zhang, ER Galemore, S VandeWoude, GA Dean	PloS one	2011
The consequence of immune suppressive cells in the use of therapeutic cancer vaccines and their importance in immune monitoring M Vergati, J Schlom, KY Tsang	Journal of biomedicine & biotechnology	2011
Immunotherapy for lung cancers MY Ho, SJ Tang, KH Sun, W Yang	Journal of biomedicine & biotechnology	2011
Clinical outcomes of active specific immunotherapy in advanced colorectal cancer and suspected minimal residual colorectal cancer: a meta-analysis and system review B Rao, M Han, L Wang, X Gao, J Huang, M Huang, H Liu, J Wang	Journal of Translational Medicine	2011
Immunosuppressive Tumor Microenvironment in Cervical Cancer Patients SJ Piersma	Cancer Microenvironment	2011
Molecular Profiling of Melanoma and the Evolution of Patient-Specific Therapy TF Gajewski	Seminars in Oncology	2011
Basic Research in Kidney Cancer E Oosterwijk, WK Rathmell, K Junker, AR Brannon, F Pouliot, DS Finley, PF Mulders, Z Kirkali, H Uemura, A Belldegrun	European Urology	2011
The Dendritic Cell-Regulatory T Lymphocyte Crosstalk Contributes to Tumor-Induced Tolerance N Janikashvili, B Bonnotte, E Katsanis, N Larmonier	Clinical and Developmental Immunology	2011
Localization of FOXP3-positive cells in renal cell carcinoma K Sell, PJ Barth, R Moll, MA Thomas, N Zimmer, E Oplesch, M Gudo, M Schrader, R Hofmann, AJ Schrader	Tumor Biology	2011
Depletion of CD25+ T cells from hematopoietic stem cell grafts increases posttransplantation vaccine-induced immunity to neuroblastoma W Jing, X Yan, WH Hallett, JA Gershan, BD Johnson	Blood	2011
Therapeutic Enhancement of Protective Immunity during Experimental Leishmaniasis S Divanovic, A Trompette, JI Ashworth, MB Rao, CL Karp	PLoS neglected tropical diseases	2011
Intratumoral Injection of Propionibacterium acnes Suppresses Malignant Melanoma by Enhancing Th1 Immune Responses K Tsuda, K Yamanaka, W Linan, Y Miyahara, T Akeda, T Nakanishi, H Kitagawa, M Kakeda, I Kurokawa, H Shiku, EC Gabazza, H Mizutani	PloS one	2011
Recruitment of regulatory T cells is correlated with hypoxia-induced CXCR4 expression, and is associated with poor prognosis in basal-like breast cancers M Yan, N Jene, D Byrne, EK Millar, SA O'Toole, CM McNeil, GJ Bates, AL Harris, AH Banham, RL Sutherland, SB Fox	Breast Cancer Research	2011
Immunotherapy of Malignant Melanoma with Tumor Lysate-Pulsed Autologous Monocyte-Derived Dendritic Cells DS Kim, DH Kim, B Goo, YH Cho, JM Park, TH Lee, HO Kim, HS Kim, H Lee, JD Lee, D Byamba, JH Je, MG Lee	Yonsei Medical Journal	2011
Adoptive cellular therapy enhances the helper T cell response and reduces the number of regulatory T cells T Ishikawa, S Kokura, N Sakamoto, T Matsumoto, J Funaki, S Adachi, T Okayama, K Uchiyama, O Handa, T Takagi, N Yagi, T Ando, K Uno, Y Naito, T Yoshikawa	Experimental and therapeutic medicine	2011
New Approaches to Immunotherapy for HPV Associated Cancers AS Bergot, A Kassianos, IH Frazer, D Mittal	Cancers	2011
Multiple vaccinations: friend or foe SE Church, SM Jensen, CG Twitty, K Bahjat, HM Hu, WJ Urba, BA Fox	Cancer journal (Sudbury, Mass.)	2011
A Role for IL-27 in Limiting T Regulatory Cell Populations ED Wojno, N Hosken, JS Stumhofer, AC OHara, E Mauldin, Q Fang, LA Turka, SD Levin, CA Hunter	Journal of immunology (Baltimore, Md. : 1950)	2011
Ontak reduces the immunosuppressive tumor environment and enhances successful therapeutic vaccination in HER-2/neu-tolerant mice Gritzapis AD, Voutsas IF, Baxevanis CN	Cancer Immunology, Immunotherapy	2011
Foxp3 expression in melanoma cells as a possible mechanism of resistance to immune destruction Niu J, Jiang C, Li C, Liu L, Li K, Jian Z, Gao T	Cancer Immunology, Immunotherapy	2011
An Alphavirus Vector Elicits Antibody and T cell Responses in the Setting of Neutralizing Antibodies and Elevated Regulatory T Cells in Humans with Advanced Cancer Michael Morse, Amy Hobeika, Takuya Osada, Peter Berglund, Bolyn Hubby, Sarah Negri, Donna Niedzwiecki, Gayathri Devi, Bruce Burnett, Timothy Clay, Jonathan Smith, Herbert K. Lyerly	Journal of Clinical Investigation	2010
Translating tumor antigens into cancer vaccines L Buonaguro, A Petrizzo, ML Tornesello, FM Buonaguro	Clinical and vaccine immunology : CVI	2010
Enhancement of dendritic cells as vaccines for cancer ME Turnis, CM Rooney	Immunotherapy	2010
Strategies for cancer vaccine development M Vergati, C Intrivici, NY Huen, J Schlom, KY Tsang	Journal of biomedicine & biotechnology	2010
RNA vaccines in cancer treatment A Bringmann, SA Held, A Heine, P Brossart	Journal of biomedicine & biotechnology	2010
Repeated PR1 and WT1 peptide vaccination in Montanide-adjuvant fails to induce sustained high-avidity, epitope-specific CD8+ T cells in myeloid malignancies K Rezvani, AS Yong, S Mielke, B Jafarpour, BN Savani, RQ Le, R Eniafe, L Musse, C Boss, R Kurlander, AJ Barrett	Haematologica	2010
Cancer vaccine by fusions of dendritic and cancer cells S Koido, E Hara, S Homma, Y Namiki, T Ohkusa, J Gong, H Tajiri	Clinical & developmental immunology	2010
Update on vaccine development for renal cell cancer N Chi, JK Maranchie, LJ Appleman, WJ Storkus	Open Access Journal of Urology	2010
1-MT enhances potency of tumor cell lysate-pulsed dendritic cells against pancreatic adenocarcinoma by downregulating the percentage of tregs Y Li, J Xu, H Zou, C Wang	Journal of Huazhong University of Science and Technology [Medical Sciences]	2010
DNA vaccines: developing new strategies against cancer D Fioretti, S Iurescia, VM Fazio, M Rinaldi	Journal of biomedicine & biotechnology	2010
Vaccines against Human Carcinomas: Strategies to Improve Antitumor Immune Responses C Palena, J Schlom	Journal of Biomedicine and Biotechnology	2010
Immunologic mechanisms in RCC and allogeneic renal transplant rejection J Bedke, A Stenzl	Nature Reviews Urology	2010
Lymphocytes in cancer development: Polarization towards pro-tumor immunity B Ruffell, DG DeNardo, NI Affara, LM Coussens	Cytokine & Growth Factor Reviews	2010
Screening of human tumor antigens for CD4 T cell epitopes by combination of HLA-transgenic mice, recombinant adenovirus and antigen peptide libraries W Osen, S Soltek, M Song, B Leuchs, J Steitz, T Tüting, SB Eichmüller, XD Nguyen, D Schadendorf, A Paschen	PloS one	2010
Polarized dendritic cells as cancer vaccines: directing effector-type T cells to tumors P Kalinski, H Okada	Seminars in Immunology	2010
Immunotherapy for renal cell carcinoma M Itsumi, K Tatsugami	Clinical & developmental immunology	2010
Anti-CTLA-4 antibody therapy: immune monitoring during clinical development of a novel immunotherapy MK Callahan, JD Wolchok, JP Allison	Seminars in Oncology	2010
Chemokine-mediated distribution of dendritic cell subsets in renal cell carcinoma P Middel, S Brauneck, W Meyer, HJ Radzun	BMC Cancer	2010
Treatment combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induces changes in the sentinel lymph nodes of mice CR Gabaglia, A DeLaney, J Gee, R Halder, FL Graham, J Gauldie, EE Sercarz, TA Braciak	Journal of Translational Medicine	2010
Phase II trial of imiquimod and HPV therapeutic vaccination in patients with vulval intraepithelial neoplasia S Daayana, E Elkord, U Winters, M Pawlita, R Roden, PL Stern, HC Kitchener	British Journal of Cancer	2010
The emergence of immunomodulation: combinatorial immunochemotherapy opportunities for the next decade LE Kandalaft, N Singh, JB Liao, A Facciabene, JS Berek, DJ Powell, G Coukos	Gynecologic Oncology	2010
The role of tregs in glioma-mediated immunosuppression: potential target for intervention W Humphries, J Wei, JH Sampson, AB Heimberger	Neurosurgery Clinics of North America	2010
Inhibiting the inhibitors: evaluating agents targeting cancer immunosuppression TL Whiteside	Expert Opinion on Biological Therapy	2010
Cancer inflammation and regulatory T cells SE Erdman, T Poutahidis	International Journal of Cancer	2010
Reduced skin homing by functional Treg in vitiligo J Klarquist, CJ Denman, C Hernandez, DJ Wainwright, FM Strickland, A Overbeck, S Mehrotra, MI Nishimura, IC le Poole	Pigment Cell & Melanoma Research	2010
Decreased Ratio of CD8+ T Cells to Regulatory T Cells Associated with Decreased Survival in Dogs with Osteosarcoma BJ Biller, A Guth, JH Burton, SW Dow	Journal of Veterinary Internal Medicine	2010
Novel role of regulatory T cells in limiting early neutrophil responses in skin H Richards, A Williams, E Jones, J Hindley, A Godkin, AK Simon, A Gallimore	Immunology	2010
Immunotherapy for Ovarian Cancer: What's Next? LE Kandalaft, DJ Powell, N Singh, G Coukos	Journal of Clinical Oncology	2010
Immune Regulation of Cancer ML Disis	Journal of Clinical Oncology	2010
Molecular profiling to identify relevant immune resistance mechanisms in the tumor microenvironment TF Gajewski, M Fuertes, R Spaapen, Y Zheng, J Kline	Current Opinion in Immunology	2010
Analysis of circulating regulatory T cells in patients with metastatic prostate cancer pre- versus post-vaccination M Vergati, V Cereda, RA Madan, JL Gulley, NY Huen, CJ Rogers, KW Hance, PM Arlen, J Schlom, KY Tsang	Cancer Immunology, Immunotherapy	2010
Radiation enhances regulatory T cell representation EL Kachikwu, KS Iwamoto, YP Liao, JJ DeMarco, N Agazaryan, JS Economou, WH McBride, D Schaue	International journal of radiation oncology, biology, physics	2010
Tumor-Associated Lymphocytes and Increased FoxP3+ Regulatory T Cell Frequency Correlate with More Aggressive Papillary Thyroid Cancer JD French, ZJ Weber, DL Fretwell, S Said, JP Klopper, BR Haugen	The Journal of clinical endocrinology and metabolism	2010
Personalized dendritic cell-based tumor immunotherapy. Janikashvili N, Larmonier N, Katsanis E	Immunotherapy	2010
Blocking ovarian cancer progression by targeting tumor microenvironmental leukocytes Cubillos-Ruiz JR, Rutkowski M, Conejo-Garcia JR	Cell cycle (Georgetown, Tex.)	2010
Immunotherapy of Malignant Gliomas Using Autologous and Allogeneic Tissue Cells Hofman FM, Stathopoulos A, Kruse CA, Chen TC, Schijns VE	Anti-cancer agents in medicinal chemistry	2010
What’s the place of immunotherapy in malignant mesothelioma treatments? Grégoire M	Cell adhesion & migration	2010
WT1 peptide vaccination in a CML patient: induction of effective cytotoxic T lymphocytes and significance of peptide administration interval. Saitoh A, Narita M, Watanabe N, Tochiki N, Yamahira A, Nakamura T, Kaji M, Masuko M, Furukawa T, Toba K, Fuse I, Aizawa Y, Takahashi M	Medical Oncology	2010
Tumor emergence is sensed by self-specific CD44hi-memory regulatory T-cells that imprint a dominant tolerant environment Guillaume Darrasse-Jèze, Anne-Sophie Bergot, Aurélie Durgeau, Fabienne Billiard, Benoît L. Salomon, José L. Cohen, Bertrand Bellier, Katrina Podsypanina and David Klatzmann	Journal of Clinical Investigation	2009
Disruption of TGF-beta signaling prevents the generation of tumor-sensitized regulatory T cells and facilitates therapeutic antitumor immunity U Petrausch, SM Jensen, C Twitty, CH Poehlein, DP Haley, EB Walker, BA Fox	Journal of immunology (Baltimore, Md. : 1950)	2009
Pulmonary surfactant: an immunological perspective ZC Chroneos, Z Sever-Chroneos, VL Shepherd	Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology	2009
Enhancing the efficacy of cancer vaccines in urologic oncology: new directions S Kusmartsev, J Vieweg	Nature Reviews Urology	2009
OX40 costimulation can abrogate Foxp3+ regulatory T cell-mediated suppression of antitumor immunity N Kitamura, S Murata, T Ueki, E Mekata, RT Reilly, EM Jaffee, T Tani	International Journal of Cancer	2009
Use of tumour-responsive T cells as cancer treatment ML Disis, H Bernhard, EM Jaffee	Lancet	2009
Tumor Vaccines for Breast Cancer KS Anderson	Cancer Investigation	2009
Immunotherapy of Diffuse Gliomas: Biological Background, Current Status and Future Developments OM Grauer, P Wesseling, GJ Adema	Brain Pathology	2009
Cyclophosphamide resets dendritic cell homeostasis and enhances antitumor immunity through effects that extend beyond regulatory T cell elimination V Radojcic, KB Bezak, M Skarica, MA Pletneva, K Yoshimura, RD Schulick, L Luznik	Cancer Immunology, Immunotherapy	2009
The role of regulatory T cells in cancer TY Ha	Immune Network	2009
Systematic analysis of immune infiltrates in high-grade serous ovarian cancer reveals CD20, FoxP3 and TIA-1 as positive prognostic factors K Milne, M Köbel, SE Kalloger, RO Barnes, D Gao, CB Gilks, PH Watson, BH Nelson	PloS one	2009
Follicular lymphoma B cells induce the conversion of conventional CD4+ T cells to T-regulatory cells WZ Ai, JZ Hou, R Zeiser, D Czerwinski, RS Negrin, R Levy	International Journal of Cancer	2009
Regulatory T cells and immune tolerance to tumors X Cao	Immunologic Research	2009
Enhancing immune responses to tumor-associated antigens JP Higgins, MB Bernstein, JW Hodge	Cancer biology & therapy	2009
Autologous MUC1-specific Th1 effector cell immunotherapy induces differential levels of systemic TReg cell subpopulations that result in increased ovarian cancer patient survival MJ Dobrzanski, KA Rewers-Felkins, IS Quinlin, KA Samad, CA Phillips, W Robinson, DJ Dobrzanski, SE Wright	Clinical Immunology	2009
Antitumor Immunity and Cancer Stem Cells T Schatton, MH Frank	Annals of the New York Academy of Sciences	2009
Immunotherapy in acute leukemia W Leung	Seminars in Hematology	2009
Targeting Treg cells in situ: emerging expansion strategies for (CD4(+)CD25(+)) regulatory T cells A Shatry, J Chirinos, MA Gorin, M Jones, RB Levy	Biology of Blood and Marrow Transplantation	2009
Identification of a human cyclin D1-derived peptide that induces human cytotoxic CD4 T cells T Dao, T Korontsvit, V Zakhaleva, K Haro, J Packin, DA Scheinberg	PloS one	2009
Cellular immunotherapy for ovarian cancer MJ Cannon, TJ O'Brien	Expert Opinion on Biological Therapy	2009
T-regulatory cell modulation: the future of cancer immunotherapy? S Nizar, J Copier, B Meyer, M Bodman-Smith, C Galustian, D Kumar, A Dalgleish	British Journal of Cancer	2009
Influence of bevacizumab, sunitinib and sorafenib as single agents or in combination on the inhibitory effects of VEGF on human dendritic cell differentiation from monocytes C Alfaro, N Suarez, A Gonzalez, S Solano, L Erro, J Dubrot, A Palazon, S Hervas-Stubbs, A Gurpide, JM Lopez-Picazo, E Grande-Pulido, I Melero, JL Perez-Gracia	British Journal of Cancer	2009
Vaccination strategies in follicular lymphoma S Kannan, SS Neelapu	Current Hematologic Malignancy Reports	2009
Engineered Interleukin-2 Antagonists for the Inhibition of Regulatory T Cells DV Liu, LM Maier, DA Hafler, KD Wittrup	Journal of Immunotherapy	2009
Harnessing innate and adaptive immunity for adoptive cell therapy of renal cell carcinoma C Geiger, E Nößner, B Frankenberger, CS Falk, H Pohla, DJ Schendel	Journal of Molecular Medicine	2009
CD4+ lymphocytes modulate prostate cancer progression in mice T Poutahidis, VP Rao, W Olipitz, CL Taylor, EA Jackson, T Levkovich, CW Lee, JG Fox, Z Ge, SE Erdman	International Journal of Cancer	2009
Tumor-derived TGF-beta mediates conversion of CD4+Foxp3+ regulatory T cells in a murine model of pancreas cancer TA Moo-Young, JW Larson, BA Belt, MC Tan, WG Hawkins, TJ Eberlein, PS Goedegebuure, DC Linehan	Journal of immunotherapy (Hagerstown, Md. : 1997)	2009
Cutting Edge: Tumor-Specific CD8 + T Cells Infiltrating Prostatic Tumors Are Induced to Become Suppressor Cells KA Shafer-Weaver, MJ Anderson, K Stagliano, A Malyguine, NM Greenberg, AA Hurwitz	Journal of immunology (Baltimore, Md. : 1950)	2009
Tumor Recognition and Self-Recognition Induce Distinct Transcriptional Profiles in Antigen-Specific CD4 T Cells D Getnet, CH Maris, EL Hipkiss, JF Grosso, TJ Harris, HR Yen, TC Bruno, S Wada, A Adler, RW Georgantas, C Jie, MV Goldberg, DM Pardoll, CG Drake	Journal of immunology (Baltimore, Md. : 1950)	2009
Cancer Immunotherapy: The Role Regulatory T cells Play and What can be Done to Overcome their Inhibitory Effects Petrausch U, Poehlein CH, Jensen SM, Twitty C, Thompson JA, Assmann I, Puri S, LaCelle MG, Moudgil T, Maston L, Friedman K, Church S, Cardenas E, Haley DP, Walker EB, Akporiaye E, Weinberg AD, Rosenheim S, Crocenzi TS, Hu HM, Curti BD, Urba WJ, Fox BA	Current molecular medicine	2009
Disruption of CCR5-dependent homing of regulatory T cells inhibits tumor growth in a murine model of pancreatic cancer Tan MC, Goedegebuure PS, Belt BA, Flaherty B, Sankpal N, Gillanders WE, Eberlein TJ, Hsieh CS, Linehan DC	Journal of immunology (Baltimore, Md. : 1950)	2009
Killer dendritic cells and their potential for cancer immunotherapy Larmonier N, Fraszczak J, Lakomy D, Bonnotte B, Katsanis E	Cancer Immunology, Immunotherapy	2009
Homeostasis of peripheral FoxP3+ CD4+ regulatory T cells in patients with early and late stage breast cancer Rech AJ, Mick R, Kaplan DE, Chang KM, Domchek SM, Vonderheide RH	Cancer Immunology, Immunotherapy	2009
Dramatic efficacy improvement of a DC-based vaccine against AML by CD25 T cell depletion allowing the induction of a long-lasting T cell response Delluc S, Hachem P, Rusakiewicz S, Gaston A, Marchiol-Fournigault C, Tourneur L, Babchia N, Fradelizi D, Regnault A, Le Quan Sang KH, Chiocchia G, Buzyn A	Cancer Immunology, Immunotherapy	2009
Vaccination strategies in patients with renal cell carcinoma Asemissen AM, Brossart P	Cancer Immunology, Immunotherapy	2009
Human CD80/IL2 lentivirus transduced acute myeloid leukaemia cells enhance cytolytic activity in vitro in spite of an increase in regulatory CD4+ T cells in a subset of cultures Ingram W, Kordasti S, Chan L, Barber LD, Tye GJ, Hardwick N, Mufti GJ, Farzaneh F	Cancer Immunology, Immunotherapy	2009
Regulatory (FOXP3+) T cells as target for immune therapy of cervical intraepithelial neoplasia and cervical cancer Loddenkemper C, Hoffmann C, Stanke J, Nagorsen D, Baron U, Olek S, Huehn J, Ritz J, Stein H, Kaufmann AM, Schneider A, Cichon G	Cancer Science	2009
Human epithelial ovarian carcinoma cell‐derived cytokines cooperatively induce activated CD4+CD25−CD45RA+ naïve T cells to express forkhead box protein 3 and exhibit suppressive ability in vitro Zhao X, Ye F, Chen L, Lu W, Xie X	Cancer Science	2009
The kinetics of CD4+ Foxp3+ T cell accumulation during a human cutaneous antigen-specific memory response in vivo M. Vukmanovic-Stejic, E. Agius, NJ. Booth, PJ Dunne, KE. Lacy, JR Reed, TO. Sobande, S.Kissane, M. Salmon, MH Rustin and AN Akbar	Journal of Clinical Investigation	2008
Transient T cell depletion causes regression of melanoma metastases MA Rasku, AL Clem, S Telang, B Taft, K Gettings, H Gragg, D Cramer, SC Lear, KM McMasters, DM Miller, J Chesney	Journal of Translational Medicine	2008
Depletion of human regulatory T cells specifically enhances antigen-specific immune responses to cancer vaccines MA Morse, AC Hobeika, T Osada, D Serra, D Niedzwiecki, HK Lyerly, TM Clay	Blood	2008
Imatinib mesylate inhibits CD4+ CD25+ regulatory T cell activity and enhances active immunotherapy against BCR-ABL- tumors N Larmonier, N Janikashvili, CJ LaCasse, CB Larmonier, J Cantrell, E Situ, T Lundeen, B Bonnotte, E Katsanis	Journal of immunology (Baltimore, Md. : 1950)	2008
FoxP3+CD4+ regulatory T cells play an important role in acute HIV-1 infection in humanized Rag2-/-gammaC-/- mice in vivo Q Jiang, L Zhang, R Wang, J Jeffrey, ML Washburn, D Brouwer, S Barbour, GI Kovalev, D Unutmaz, L Su	Blood	2008
The anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells C Galustian, B Meyer, MC Labarthe, K Dredge, D Klaschka, J Henry, S Todryk, R Chen, G Muller, D Stirling, P Schafer, JB Bartlett, AG Dalgleish	Cancer Immunology, Immunotherapy	2008
Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma SA Quezada, KS Peggs, TR Simpson, Y Shen, DR Littman, JP Allison	Journal of Experimental Medicine	2008
The capacity of the TNF family members 4-1BBL, OX40L, CD70, GITRL, CD30L and LIGHT to costimulate human T cells J Kober, J Leitner, C Klauser, R Woitek, O Majdic, J Stöckl, D Herndler-Brandstetter, B Grubeck-Loebenstein, BM Reipert, WF Pickl, K Pfistershammer, P Steinberger	European Journal of Immunology	2008
Induction of antigen-specific cytotoxic T lymphocytes by using monocyte-derived DCs transfected with in vitro-transcribed WT1 or SART1 mRNA M Narita, N Tochiki, A Saitoh, N Watanabe, M Kaji, N Satoh, A Yamahira, T Nakamura, M Masuko, T Furukawa, K Toba, I Fuse, Y Aizawa, M Takahashi	Medical Oncology	2008
Characterizing and optimizing immune responses to leukaemia antigens after allogeneic stem cell transplantation K Rezvani, CS Lecturer, AJ Barrett	Best practice & research. Clinical haematology	2008
Immunotherapy of malignant brain tumors DA Mitchell, PE Fecci, JH Sampson	Immunological Reviews	2008
Combination therapy using IL-2 and anti-CD25 results in augmented natural killer cell-mediated antitumor responses WH Hallett, E Ames, M Alvarez, I Barao, PA Taylor, BR Blazar, WJ Murphy	Biology of Blood and Marrow Transplantation	2008
Regulatory T cells and human disease N Cools, P Ponsaerts, VF van Tendeloo, ZN Berneman	Clinical & developmental immunology	2008
Immunoregulatory T cells: Role and potential as a target in malignancy M Beyer, JL Schultze	Current Oncology Reports	2008
CTLA4 blockade expands FoxP3+ regulatory and activated effector CD4+ T cells in a dose-dependent fashion B Kavanagh, S O'Brien, D Lee, Y Hou, V Weinberg, B Rini, JP Allison, EJ Small, L Fong	Blood	2008
Developing idiotype vaccines for lymphoma: from preclinical studies to phase III clinical trials HJ Park, SS Neelapu	British Journal of Haematology	2008
T-cell responses to survivin in cancer patients undergoing radiation therapy D Schaue, B Comin-Anduix, A Ribas, L Zhang, L Goodglick, JW Sayre, A Debucquoy, K Haustermans, WH McBride	Clinical cancer research	2008
Dendritic cells: a critical player in cancer therapy? AK Palucka, H Ueno, J Fay, J Banchereau	Journal of immunotherapy (Hagerstown, Md. : 1997)	2008
Adoptive T-cell immunotherapy of chronic lymphocytic leukaemia AE Foster, MK Brenner, G Dotti	Best practice & research. Clinical haematology	2008
FOXP3 expression accurately defines the population of intratumoral regulatory T cells that selectively accumulate in metastatic melanoma lesions M Ahmadzadeh, A Felipe-Silva, B Heemskerk, DJ Powell, JR Wunderlich, MJ Merino, SA Rosenberg	Blood	2008
Selective accumulation of differentiated FOXP3(+) CD4 (+) T cells in metastatic tumor lesions from melanoma patients compared to peripheral blood C Jandus, G Bioley, DE Speiser, P Romero	Cancer Immunology, Immunotherapy	2008
Toll-like receptor signalling on Tregs: to suppress or not to suppress? WW van Maren, JF Jacobs, IJ de Vries, S Nierkens, GJ Adema	Immunology	2008
Enhancing the in vivo expansion of adoptively transferred EBV-specific CTL with lymphodepleting CD45 monoclonal antibodies in NPC patients CU Louis, K Straathof, CM Bollard, C Gerken, MH Huls, MV Gresik, MF Wu, HL Weiss, AP Gee, MK Brenner, CM Rooney, HE Heslop, S Gottschalk	Blood	2008
Phase Ib trial assessing autologous, tumor-pulsed dendritic cells as a vaccine administered with or without IL-2 in patients with metastatic melanoma BG Redman, AE Chang, J Whitfield, P Esper, G Jiang, T Braun, B Roessler, JJ Mulé	Journal of immunotherapy (Hagerstown, Md. : 1997)	2008
Comparative methodologies of regulatory T cell depletion in a murine melanoma model N Matsushita, SA Pilon-Thomas, LM Martin, AI Riker	Journal of Immunological Methods	2008
Special regulatory T-cell review: T-cell dependent suppression revisited A Basten, BF de st Groth	Immunology	2008
Studies on mRNA Electroporation of Immature and Mature Dendritic Cells: Effects on their Immunogenic Potential Ö Met, J Eriksen, IM Svane	Molecular Biotechnology	2008
Three phase II cytokine working group trials of gp100 (210M) peptide plus high-dose interleukin-2 in patients with HLA-A2-positive advanced melanoma JA Sosman, C Carrillo, WJ Urba, L Flaherty, MB Atkins, JI Clark, J Dutcher, KA Margolin, J Mier, J Gollob, JM Kirkwood, DJ Panka, NA Crosby, K O'Boyle, B LaFleur, MS Ernstoff	Journal of Clinical Oncology	2008
Partial reduction of human FOXP3+ CD4 T cells in vivo after CD25-directed recombinant immunotoxin administration DJ Powell, P Attia, V Ghetie, J Schindler, ES Vitetta, SA Rosenberg	Journal of immunotherapy (Hagerstown, Md. : 1997)	2008
A20 is an antigen presentation attenuator, and its inhibition overcomes regulatory T cell-mediated suppression XT Song, K Evel-Kabler, L Shen, L Rollins, XF Huang, SY Chen	Nature Medicine	2008
FOXP3+ Tregs and B7-H1+/PD-1+T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: Implication for immunotherapy H Ghebeh, E Barhoush, A Tulbah, N Elkum, T Al-Tweigeri, S Dermime	BMC Cancer	2008
Paradigm Shifts in Cancer Vaccine Therapy J Schlom, JL Gulley, PM Arlen	Experimental biology and medicine (Maywood, N.J.)	2008
Tumor-Specific T-Cell Memory: Clearing the Regulatory T-Cell Hurdle: Figure 1 AL Côté, EJ Usherwood, MJ Turk	Cancer research	2008
STRATEGIES TO OVERCOME OBSTACLES TO SUCCESSFUL IMMUNOTHERAPY OF MELANOMA Pandolfi F, Cianci R, Lolli S, Dunn IS, Newton EE, Haggerty TJ, Boyle LA, Kurnick JT	International journal of immunopathology and pharmacology	2008
Targeting Cyclooxygenase-2 in Hematological Malignancies: Rationale and Promise Bernard MP, Bancos S, Sime PJ, Phipps RP	Current pharmaceutical design	2008
Fusions of Dendritic Cells with Breast Carcinoma Stimulate the Expansion of Regulatory T Cells while Concomitant Exposure to IL-12, CpG Oligodeoxynucleotides, and Anti-CD3/CD28 Promotes the Expansion of Activated Tumor Reactive Cells Vasir B, Wu Z, Crawford K, Rosenblatt J, Zarwan C, Bissonnette A, Kufe D, Avigan D	Journal of immunology (Baltimore, Md. : 1950)	2008
Dendritic cell vaccination and other strategies to tip the balance of the immune system: DC2007 5th international meeting, July 16–18, Bamberg, Germany Schaft N, Birkholz K, Hofmann C, Schmid M, Theiner G, Dörrie J	Cancer Immunology, Immunotherapy	2008
Development of a dendritic cell-based vaccine for chronic lymphocytic leukemia Palma M, Adamson L, Hansson L, Kokhaei P, Rezvany R, Mellstedt H, Österborg A, Choudhury A	Cancer Immunology, Immunotherapy	2008
Possible involvement of regulatory T cells in tumor onset and progression in primary breast cancer Ohara M, Yamaguchi Y, Matsuura K, Murakami S, Arihiro K, Okada M	Cancer Immunology, Immunotherapy	2008
The immunosuppressive tumor microenvironment in hepatocellular carcinoma Pang YL, Zhang HG, Peng JR, Pang XW, Yu S, Xing Q, Yu X, Gong L, Yin YH, Zhang Y, Chen WF	Cancer Immunology, Immunotherapy	2008
Dendritic cell–based cancer vaccines Eli Gilboa	Journal of Clinical Investigation	2007
Series overview: Harnessing the immune system to treat cancer Nina Bhardwaj	Journal of Clinical Investigation	2007
Tregs and rethinking cancer immunotherapy Tyler J. Curiel	Journal of Clinical Investigation	2007
T regulatory cells: aid or hindrance in the clearance of disease? CA Coleman, MC Muller-Trutwin, C Apetrei, I Pandrea	Journal of Cellular and Molecular Medicine	2007
Molecular determinants of immunogenic cell death: surface exposure of calreticulin makes the difference N Chaput, S Botton, M Obeid, L Apetoh, F Ghiringhelli, T Panaretakis, C Flament, L Zitvogel, G Kroemer	Journal of Molecular Medicine	2007
Regulatory T cells in the prevention of mucosal inflammatory diseases: patrolling the border RY Lan, IR Mackay, ME Gershwin	Journal of Autoimmunity	2007
Peptide vaccine given with a Toll-like receptor agonist is effective for the treatment and prevention of spontaneous breast tumors P Nava-Parada, G Forni, KL Knutson, LR Pease, E Celis	Cancer research	2007
Therapeutic vaccine for lymphoma ST Lee, SS Neelapu, LW Kwak	Yonsei Medical Journal	2007
IPEX as a result of mutations in FOXP3 HJ van der Vliet, EE Nieuwenhuis	Clinical & developmental immunology	2007
Stromal mast cells in invasive breast cancer are a marker of favourable prognosis: a study of 4,444 cases AB Rajput, DA Turbin, MC Cheang, DK Voduc, S Leung, KA Gelmon, CB Gilks, DG Huntsman	Breast Cancer Research and Treatment	2007
Regulatory T cells and tumour immunity - observations in mice and men A Gallimore, A Godkin	Immunology	2007
Frequencies and role of regulatory T cells in patients with (pre)malignant cervical neoplasia J Visser, HW Nijman, BN Hoogenboom, P Jager, D Baarle, E Schuuring, W Abdulahad, F Miedema, AG van der Zee, T Daemen	Clinical & Experimental Immunology	2007
Induction of postsurgical tumor immunity and T-cell memory by a poorly immunogenic tumor P Zhang, AL Côté, VC de Vries, EJ Usherwood, MJ Turk	Cancer research	2007
IL-2 immunotoxin denileukin diftitox reduces regulatory T cells and enhances vaccine-mediated T-cell immunity MT Litzinger, R Fernando, TJ Curiel, DW Grosenbach, J Schlom, C Palena	Blood	2007
Association of cervical cancer with the presence of CD4+ regulatory T cells specific for human papillomavirus antigens SH van der Burg, SJ Piersma, A Jong, JM van der Hulst, KM Kwappenberg, M Hende, MJ Welters, JJ van Rood, GJ Fleuren, CJ Melief, GG Kenter, R Offringa	Proceedings of the National Academy of Sciences	2007
Cancer vaccines: moving beyond current paradigms J Schlom, PM Arlen, JL Gulley	Clinical cancer research	2007
Translational mini-review series on vaccines: Dendritic cell-based vaccines in renal cancer E Ranieri, M Gigante, WJ Storkus, L Gesualdo	Clinical & Experimental Immunology	2007
Cancer vaccines in old age C Gravekamp	Experimental Gerontology	2007
Role of vaccine therapy in cancer: biology and practice Schlom J, Gulley JL, Arlen PM	Current Oncology	2007
Administration of a CD25-Directed Immunotoxin, LMB-2, to Patients with Metastatic Melanoma Induces a Selective Partial Reduction in Regulatory T Cells In Vivo Powell DJ Jr, Felipe-Silva A, Merino MJ, Ahmadzadeh M, Allen T, Levy C, White DE, Mavroukakis S, Kreitman RJ, Rosenberg SA, Pastan I	Journal of immunology (Baltimore, Md. : 1950)	2007
Treg cells, cancer vaccines: timing is everything Kalinski P	Blood	2007
Reply: Forkhead box P3-positive regulatory T cells in immune surveillance and cancer Betts G, Godkin A, Gallimore A	British Journal of Cancer	2007
Dynamic cross-talk between tumor and immune cells in orchestrating the immunosuppressive network at the tumor microenvironment DO Croci, MF Fluck, MJ Rico, P Matar, GA Rabinovich, OG Scharovsky	Cancer Immunology, Immunotherapy	2007
Strategies for immune intervention; from bench to bedside: Symposium 2006 of the Collaborative Research Center “Strategies of cellular immune intervention” July 17th–18th, Erlangen, Germany Dörrie J, Birkholz K, Schaft N	Cancer Immunology, Immunotherapy	2007
Adoptive transfer of Treg depleted autologous T cells in advanced renal cell carcinoma Thistlethwaite FC, Elkord E, Griffiths RW, Burt DJ, Shablak AM, Campbell JD, Gilham DE, Austin EB, Stern PL, Hawkins RE	Cancer Immunology, Immunotherapy	2007
Current approaches in dendritic cell generation and future implications for cancer immunotherapy Tuyaerts S, Aerts JL, Corthals J, Neyns B, Heirman C, Breckpot K, Thielemans K, Bonehill A	Cancer Immunology, Immunotherapy	2007
Adoptive transfer of autologous, HER2-specific, cytotoxic T lymphocytes for the treatment of HER2-overexpressing breast cancer Bernhard H, Neudorfer J, Gebhard K, Conrad H, Hermann C, Nährig J, Fend F, Weber W, Busch DH, Peschel C	Cancer Immunology, Immunotherapy	2007
Frequency of regulatory T cells in renal cell carcinoma patients and investigation of correlation with survival Griffiths RW, Elkord E, Gilham DE, Ramani V, Clarke N, Stern PL, Hawkins RE	Cancer Immunology, Immunotherapy	2007
Expression of indoleamine 2, 3‐dioxygenase and the recruitment of Foxp3‐expressing regulatory T cells in the development and progression of uterine cervical cancer Nakamura T, Shima T, Saeki A, Hidaka T, Nakashima A, Takikawa O, Saito S	Cancer Science	2007
Depletion of CD4+CD25+ regulatory T cells enhances interleukin‐2‐induced antitumor immunity in a mouse model of colon adenocarcinoma Imai H, Saio M, Nonaka K, Suwa T, Umemura N, Ouyang G, Nakagawa J, Tomita H, Osada S, Sugiyama Y, Adachi Y, Takami T	Cancer Science	2007
CD8+ T-cell memory in tumor immunology and immunotherapy CA Klebanoff, L Gattinoni, NP Restifo	Immunological Reviews	2006
Adoptive immunotherapy for cancer: building on success L Gattinoni, DJ Powell, SA Rosenberg, NP Restifo	Nature Reviews Immunology	2006
Regulatory T cells and innate immune regulation in tumor immunity RF Wang	Springer Seminars in Immunopathology	2006
CD4+CD25+FOXP3+ regulatory T cells suppress anti-tumor immune responses in patients with colorectal cancer SL Clarke, GJ Betts, A Plant, KL Wright, TM El-Shanawany, R Harrop, J Torkington, BI Rees, GT Williams, AM Gallimore, AJ Godkin	PloS one	2006
Expansion of FOXP3high regulatory T cells by human dendritic cells (DCs) in vitro and after injection of cytokine-matured DCs in myeloma patients DK Banerjee, MV Dhodapkar, E Matayeva, RM Steinman, KM Dhodapkar	Blood	2006
T cell responses in melanoma patients after vaccination with tumor-mRNA transfected dendritic cells Kyte JA, Kvalheim G, Lislerud K, thor Straten P, Dueland S, Aamdal S, Gaudernack G	Cancer Immunology, Immunotherapy	2006
Immuno-gene therapy of cancer with tumour-mRNA transfected dendritic cells Kyte JA, Gaudernack G	Cancer Immunology, Immunotherapy	2006
Non-viral in vivo immune gene therapy of cancer: combined strategies for treatment of systemic disease Tangney M, Casey G, Larkin JO, Collins CG, Soden D, Cashman J, Whelan MC, O\u2019Sullivan GC	Cancer Immunology, Immunotherapy	2006
An immune edited tumour versus a tumour edited immune system: prospects for immune therapy of acute myeloid leukaemia Chan L, Hardwick NR, Guinn BA, Darling D, Gäken J, Galea-Lauri J, Ho AY, Mufti GJ, Farzaneh F	Cancer Immunology, Immunotherapy	2006
The role of CD4+ T cell help in cancer immunity and the formulation of novel cancer vaccines Assudani DP, Horton RB, Mathieu MG, McArdle SE, Rees RC	Cancer Immunology, Immunotherapy	2006
Small numbers of residual tumor cells at the site of primary inoculation are critical for anti-tumor immunity following challenge at a secondary location Kakinuma T, Nadiminti H, Lonsdorf AS, Murakami T, Perez BA, Kobayashi H, Finkelstein SE, Pothiawala G, Belkaid Y, Hwang ST	Cancer Immunology, Immunotherapy	2006
The strange case of TGN1412 Farzaneh L, Kasahara N, Farzaneh F	Cancer Immunology, Immunotherapy	2006
Immunotherapy of renal cell carcinoma Gouttefangeas C, Stenzl A, Stevanović S, Rammensee HG	Cancer Immunology, Immunotherapy	2006
CD4 regulatory T cells in human cancer pathogenesis Knutson KL, Disis ML, Salazar LG	Cancer Immunology, Immunotherapy	2006

Advertisement