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Usage Information

The genetic epidemiology of neurodegenerative disease
Lars Bertram, Rudolph E. Tanzi
Lars Bertram, Rudolph E. Tanzi
Published June 1, 2005
Citation Information: J Clin Invest. 2005;115(6):1449-1457. https://doi.org/10.1172/JCI24761.
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Review Series Article has an altmetric score of 29

The genetic epidemiology of neurodegenerative disease

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Abstract

Gene defects play a major role in the pathogenesis of degenerative disorders of the nervous system. In fact, it has been the very knowledge gained from genetic studies that has allowed the elucidation of the molecular mechanisms underlying the etiology and pathogenesis of many neurodegenerative disorders. In this review, we discuss the current status of genetic epidemiology of the most common neurodegenerative diseases: Alzheimer disease, Parkinson disease, Lewy body dementia, frontotemporal dementia, amyotrophic lateral sclerosis, Huntington disease, and prion diseases, with a particular focus on similarities and differences among these syndromes.

Authors

Lars Bertram, Rudolph E. Tanzi

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Usage data is cumulative from May 2024 through May 2025.

Usage JCI PMC
Text version 3,411 1,626
PDF 323 174
Figure 595 28
Table 71 0
Citation downloads 109 0
Totals 4,509 1,828
Total Views 6,337
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