Citations to this article

Marfan syndrome and mitral valve prolapse
Arthur E. Weyman, Marielle Scherrer-Crosbie
Arthur E. Weyman, Marielle Scherrer-Crosbie
Published December 1, 2004
Citation Information: J Clin Invest. 2004;114(11):1543-1546. https://doi.org/10.1172/JCI23701.
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Marfan syndrome and mitral valve prolapse

Abstract

Mitral valve prolapse (MVP), an abnormal displacement into the left atrium of a thickened and redundant mitral valve during systole, is a relatively frequent abnormality in humans and may be associated with serious complications. A recent study implicates fibrillin-1, a component of extracellular matrix microfibrils, in the pathogenesis of a murine model of MVP. This investigation represents an initial step toward understanding the mechanisms involved in human MVP disease and the development of potential treatments.

Authors

Arthur E. Weyman, Marielle Scherrer-Crosbie

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Citations to this article (15)

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Mendelian randomization reveals interactions of the blood proteome and immunome in mitral valve prolapse
Minvielle Moncla LH, Briend M, Sokhna Sylla M, Mathieu S, Rufiange A, Bossé Y, Mathieu P 		2024
Meary angle for the prediction of mitral valve prolapse risk in non-syndromic patients with pes planus, a cross-sectional study
AbdelMassih A, Hozaien R, Mishriky F, Michael M, AmanAllah M, Ali N, ElGamal N, Medhat O, Kamel M, Helmy R, Sarhan M, Attalla H, Dawoud O, Marwan A, Ghobashy M 		BMC Research Notes 2022
Should mitral valve prolapse be considered as one of the risk factors for open angle glaucoma? A preliminary observation
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Karamichos D, Escandon P, Vasini B, Nicholas SE, Van L, Dang DH, Cunningham RL, Riaz KM 		Progress in Retinal and Eye Research 2021
Identification of Patients Affected by Mitral Valve Prolapse with Severe Regurgitation: A Multivariable Regression Model
Songia P, Porro B, Chiesa M, Myasoedova V, Alamanni F, Tremoli E, Poggio P 		Oxidative medicine and cellular longevity 2017
Echocardiographic versus Histologic Findings in Marfan Syndrome
Gu X, He Y, Li Z, Han J, Chen J, Nixon JV 		Texas Heart Institute Journal 2015
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VK Krishnamurthy, RC Godby, GR Liu, JM Smith, LF Hiratzka, DA Narmoneva, RB Hinton 		Journal of Cardiovascular Translational Research 2014
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RA Gould, R Sinha, H Aziz, R Rouf, HC 3rd, DP Judge, J Butcher 		PloS one 2012
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Howden R, Cho HY, Miller-DeGraff L, Walker C, Clark JA, Myers PH, Rouse DC, Kleeberger SR 		American journal of respiratory cell and molecular biology 2012
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Cardiac transgenic matrix metalloproteinase-2 expression induces myxomatous valve degeneration: a potential model of mitral valve prolapse disease
R Mahimkar, A Nguyen, M Mann, CC Yeh, BQ Zhu, JS Karliner, DH Lovett 		Cardiovascular Pathology 2009
Applying elastic fibre biology in vascular tissue engineering
CM Kielty, S Stephan, MJ Sherratt, M Williamson, CA Shuttleworth 		Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2007
Adult women with mitral valve prolapse are more flexible
Araujo C, Chaves C 		British journal of sports medicine 2005

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