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Citations to this article

Anti–β1-adrenergic receptor antibodies and heart failure: causation, not just correlation
Neil J. Freedman, Robert J. Lefkowitz
Neil J. Freedman, Robert J. Lefkowitz
Published May 15, 2004
Citation Information: J Clin Invest. 2004;113(10):1379-1382. https://doi.org/10.1172/JCI21748.
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Commentary Article has an altmetric score of 6

Anti–β1-adrenergic receptor antibodies and heart failure: causation, not just correlation

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Abstract

Antibodies specific for the β1-adrenergic receptor are found in patients with chronic heart failure of various etiologies. From work presented in this issue of the JCI, we can now infer that these antibodies actually contribute to the pathogenesis of chronic heart failure. This commentary discusses mechanisms by which these antibodies may engender cardiomyopathy.

Authors

Neil J. Freedman, Robert J. Lefkowitz

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Total citations by year

Year: 2025 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Total
Citations: 2 4 2 1 1 2 4 1 3 2 1 2 3 1 1 3 1 1 1 1 1 38
Citation information
This citation data is accumulated from CrossRef, which receives citation information from participating publishers, including this journal. Not all publishers participate in CrossRef, so this information is not comprehensive. Additionally, data may not reflect the most current citations to this article, and the data may differ from citation information available from other sources (for example, Google Scholar, Web of Science, and Scopus).

Citations to this article (38)

Title and authors Publication Year
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Frontiers in immunology 2025
Autoimmunity in Cardiomyopathy-Induced Heart Failure and Cardiac Autoantibody Removal by Immunoadsorption
Dandel M
Journal of Clinical Medicine 2025
Comparison of COVID-19 Vaccine-Associated Myocarditis and Viral Myocarditis Pathology
Hamedi KR, Loftus G, Traylor L, Goodwin R, Arce S
Human vaccines 2023
A novel vaccine targeting β1-adrenergic receptor.
Ke F, Kuang W, Hu X, Li C, Ma W, Shi D, Li X, Wu Z, Zhou Y, Liao Y, Qiu Z, Zhou Z
Hypertension research : official journal of the Japanese Society of Hypertension 2023
Is ischaemic heart failure an autoimmune disease?
Sattler S
ESC Heart Failure 2023
Status of β1-Adrenoceptor Signal Transduction System in Cardiac Hypertrophy and Heart Failure
Dhalla NS, Bhullar SK, Adameova A, Mota KO, de Vasconcelos CM
2023
Galectins in Chagas Disease: A Missing Link Between Trypanosoma cruzi Infection, Inflammation, and Tissue Damage.
Poncini CV, Benatar AF, Gomez KA, Rabinovich GA
Frontiers in microbiology 2022
Influence of β(1) Adrenergic Receptor Genotype on Longitudinal Measures of Left Ventricular Ejection Fraction and Responsiveness to ß-Blocker Therapy in Patients With Duchenne Muscular Dystrophy.
Kelley EF, Cross TJ, McDonald CM, Investigators C, Hoffman EP, Spurney CF, Bello L
Clinical Medicine Insights. Cardiology 2022
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Journal of animal science 2021
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JA Borovac, D D'Amario, J Bozic, D Glavas
World journal of cardiology 2020
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W Xu, Y Wu, L Wang, Y Bai, Y Du, Y Li, N Cao, Y Zhao, Y Zhang, H Liu
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Messerli M, Maredziak M, Bengs S, Haider A, Giannopoulos AA, Schwyzer M, Benz DC, von Felten E, Kudura K, Treyer V, Fiechter M, Gräni C, Fuchs TA, Pazhenkottil AP, Buechel RR, Kaufmann PA, Gebhard C
The International Journal of Cardiovascular Imaging 2019
Regulatory Role of CD4 + T Cells in Myocarditis
D Vdovenko, U Eriksson
Journal of Immunology Research 2018
Cyclopeptide COR-1 to treat beta1-adrenergic receptor antibody-induced heart failure
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PloS one 2018
Cyclic peptide RD808 reduces myocardial injury induced by β1-adrenoreceptor autoantibodies
Y Dong, Y Bai, S Zhang, W Xu, J Xu, Y Zhou, S Zhang, Y Wu, H Yu, N Cao, H Liu, W Wang
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Kelley EF, Snyder EM, Johnson BD
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Khalilimeybodi A, Daneshmehr A, Sharif-Kashani B
The journal of physiological sciences : JPS 2017
Review of Mouse Models of Graves’ Disease and Orbitopathy—Novel Treatment by Induction of Tolerance
M Ungerer, J Faßbender, Z Li, G Münch, HP Holthoff
Clinical Reviews in Allergy & Immunology 2016
Glycyrrhizic Acid Reduces Heart Rate and Blood Pressure by a Dual Mechanism
K Singh, A Zaw, R Sekar, A Palak, A Allam, J Ajarem, B Chow
Molecules (Basel, Switzerland) 2016
Pharmacokinetics and Safety of Single Intravenous Doses of JNJ-54452840, an Anti-β1-Adrenergic Receptor Antibody Cyclopeptide, in Healthy Male Japanese and Caucasian Participants.
Nnane IP, Plotnikov AH, Peters G, Johnson M, Kojak C, Vutikullird A, Ariyawansa J, De Vries R, Davies BE
Clinical Pharmacokinetics 2016
Novel Receptor-Derived Cyclopeptides to Treat Heart Failure Caused by Anti-β1-Adrenoceptor Antibodies in a Human-Analogous Rat Model
V Boivin, N Beyersdorf, D Palm, VO Nikolaev, A Schlipp, J Müller, D Schmidt, V Kocoski, T Kerkau, T Hünig, G Ertl, MJ Lohse, R Jahns, MA Sussman
PloS one 2015
Palmitoyl acyltransferase Aph2 in cardiac function and the development of cardiomyopathy
T Zhou, J Li, P Zhao, H Liu, D Jia, H Jia, L He, Y Cang, S Boast, YH Chen, H Thibault, M Scherrer-Crosbie, SP Goff, B Li
Proceedings of the National Academy of Sciences 2015
Rethinking Molecular Mimicry in Rheumatic Heart Disease and Autoimmune Myocarditis: Laminin, Collagen IV, CAR, and B1AR as Initial Targets of Disease
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Targeting anti-beta-1-adrenergic receptor antibodies for dilated cardiomyopathy
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European Journal of Heart Failure 2013
Stimulatory effect of nobiletin, a citrus polymethoxy flavone, on catecholamine synthesis through Ser19 and Ser40 phosphorylation of tyrosine hydroxylase in cultured bovine adrenal medullary cells.
Zhang H, Yanagihara N, Toyohira Y, Takahashi K, Inagaki H, Satoh N, Li X, Goa X, Tsutsui M, Takahaishi K
Naunyn-Schmiedeberg's Archives of Pharmacology 2013
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V Boivin-Jahns, A Schlipp, S Hartmann, P Panjwani, K Klingel, MJ Lohse, G Ertl, R Jahns
Herz 2012
β1-Adrenoceptor autoantibodies from DCM patients enhance the proliferation of T lymphocytes through the β1-AR/cAMP/PKA and p38 MAPK pathways
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PloS one 2012
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Machado FS, Tyler KM, Brant F, Esper L, Teixeira MM, Tanowitz HB
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The Clinical Significance of Anti-Beta-1 Adrenergic Receptor Autoantibodies in Cardiac Disease
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Clinical Reviews in Allergy & Immunology 2010
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Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2009
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The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2009
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A Mascaro-Blanco, K Alvarez, X Yu, JA Lindenfeld, L Olansky, T Lyons, D Duvall, JS Heuser, A Gosmanova, CJ Rubenstein, LT Cooper, DC Kem, MW Cunningham
Autoimmunity 2008
Real-time optical recording of beta1-adrenergic receptor activation reveals supersensitivity of the Arg-389 variant to carvedilol
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Naunyn-Schmiedeberg's Archives of Pharmacology 2005
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