Citations to this article

Achieving antigen-specific immune regulation
Kevan C. Herold
Kevan C. Herold
Published February 1, 2004
Citation Information: J Clin Invest. 2004;113(3):346-349. https://doi.org/10.1172/JCI20963.
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Achieving antigen-specific immune regulation

Abstract

A study in this issue of the JCI shows that in response to autoantigens consisting of peptides from normal proteins, patients with diabetes mount a T cell response characterized by production of IFN-γ . However, in response to these same antigens, T cells from normal control subjects produce IL-10. The antigen-specific response characterized by release of a regulatory cytokine suggests a mechanism for the control of autoimmunity that is initiated at the time of antigen presentation.

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Kevan C. Herold

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Citations to this article (9)

Title and authors Publication Year
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P Ramakrishnan, PM Clark, DE Mason, EC Peters, LC Hsieh-Wilson, D Baltimore 		Science signaling 2013
Effects of recombinant human interleukin-10 on Treg cells, IL-10 and TGF-β in transplantation of rabbit skin
LIU KS, FAN XQ, ZHANG L, WEN QN, FENG JH, CHEN FC, LUO JM, SUN WB 		Molecular medicine reports 2013
Teplizumab therapy for type 1 diabetes
UB Masharani, J Becker 		Expert Opinion on Biological Therapy 2010
Regulatory T cell-associated activity in photopheresis-induced immune tolerance in recent onset type 1 diabetes children
CO Jonson, M Pihl, C Nyholm, CM Cilio, J Ludvigsson, M Faresjö 		Clinical & Experimental Immunology 2008
New potential treatments for protection of pancreatic B-cell function in Type 1 diabetes
S Cernea, P Pozzilli 		Diabetic medicine : a journal of the British Diabetic Association 2008
Interleukin-10 Inhibits Gram-Negative-Microbe-Specific Human Receptor Activator of NF-κB Ligand-Positive CD4 + -Th1-Cell- Associated Alveolar Bone Loss In Vivo
X Zhang, YT Teng 		Infection and immunity 2006
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YT Teng, D Mahamed, B Singh 		Infection and immunity 2005
Regulatory T cells and type 1 diabetes.
Bisikirska BC, Herold KC 		Current Diabetes Reports 2005
Treatment of type 1 diabetes with anti-T-cell agents: From T-cell depletion to T-cell regulation
M Glandt, KC Herold 		Current Diabetes Reports 2004

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