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Citations to this article

The TRAIL to arthritis
George C. Tsokos, Maria Tsokos
George C. Tsokos, Maria Tsokos
Published November 1, 2003
Citation Information: J Clin Invest. 2003;112(9):1315-1317. https://doi.org/10.1172/JCI20297.
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Commentary

The TRAIL to arthritis

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Abstract

Antigen-specific lymphocytes are involved in synovial proliferation within inflamed joints. Activated lymphocytes and synoviocytes from patients with rheumatoid arthritis express receptors that can bind TNF-related apoptosis-inducing ligand (TRAIL). A new study demonstrates that DCs pulsed with collagen and transduced with an adenovirus-based vector able to express TRAIL limit the incidence of arthritis in a model of collagen-induced arthritis and joint inflammation. These results suggest that gene-modified cell therapy represents a therapeutic option for systemic rheumatic diseases.

Authors

George C. Tsokos, Maria Tsokos

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Total citations by year

Year: 2018 2012 2011 2010 Total
Citations: 1 1 1 1 4
Citation information
This citation data is accumulated from CrossRef, which receives citation information from participating publishers, including this journal. Not all publishers participate in CrossRef, so this information is not comprehensive. Additionally, data may not reflect the most current citations to this article, and the data may differ from citation information available from other sources (for example, Google Scholar, Web of Science, and Scopus).

Citations to this article (4)

Title and authors Publication Year
Defective T-Cell Apoptosis and T-Regulatory Cell Dysfunction in Rheumatoid Arthritis.
Malemud CJ
Cells 2018
Soluble trail as a marker of efficacy of allergen-specific immunotherapy in patients with allergic rhinoconjunctivitis.
Yalcin AD, Gumuslu S, Parlak GE, Bısgın A
Medical science monitor : international medical journal of experimental and clinical research 2012
Apigenin enhances the cytotoxic effects of tumor necrosis factor-related apoptosis-inducing ligand in human rheumatoid arthritis fibroblast-like synoviocytes
Q Sun, S Jiang, K Yang, J Zheng, L Zhang, W Xu
Molecular Biology Reports 2011
TRAIL death receptor-4, decoy receptor-1 and decoy receptor-2 expression on CD8+ T cells correlate with the disease severity in patients with rheumatoid arthritis
A Bisgin, E Terzioglu, C Aydin, B Yoldas, V Yazisiz, N Balci, H Bagci, RM Gorczynski, CA Akdis, S Sanlioglu
BMC musculoskeletal disorders 2010

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