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Endocannabinoids and the regulation of body fat: the smoke is clearing
Tamas L. Horvath
Tamas L. Horvath
Published August 1, 2003
Citation Information: J Clin Invest. 2003;112(3):323-326. https://doi.org/10.1172/JCI19376.
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Endocannabinoids and the regulation of body fat: the smoke is clearing

Abstract

Endocannabinoids, endogenous ligands of cannabinoid receptor type 1 (CB1), have emerged as novel and important regulators of energy homeostasis. A report in this issue demonstrates reduced body weight, fat mass, and appetite in CB1–/– mice. Examination of the underlying mechanisms reveals a dual role for endocannabinoids as they affect both appetite and peripheral lipolysis.

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Tamas L. Horvath

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Citations to this article (18)

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YM Morozov, M Koch, P Rakic, TL Horvath 		Molecular Metabolism 2017
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Deletion of G-protein-coupled receptor 55 promotes obesity by reducing physical activity
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