Research Article
Robin Parihar, Julie Dierksheide, Yan Hu, William E. Carson
Title and authors | Publication | Year |
---|---|---|
Natural killer cells: the immune frontline against circulating tumor cells
Masmoudi D, Villalba M, Alix-Panabières C |
Journal of Experimental & Clinical Cancer Research : CR | 2025 |
Machine learning unveils an immune-related DNA methylation profile in germline DNA from breast cancer patients
Lee NY, Hum M, Tan GP, Seah AC, Ong PY, Kin PT, Lim CW, Samol J, Tan NC, Law HY, Tan MH, Lee SC, Ang P, Lee AS |
Clinical Epigenetics | 2024 |
An Open-Label Study of Subcutaneous CpG Oligodeoxynucleotide (PF03512676) in Combination with Trastuzumab in Patients with Metastatic HER2+ Breast Cancer.
Quiroga D, Wesolowski R, Zelinskas S, Pinette A, Benner B, Schwarz E, Savardekar H, Johnson C, Stiff A, Yu L, Macrae E, Lustberg M, Mrozek E, Ramaswamy B, Carson WE 3rd |
Cancer control : journal of the Moffitt Cancer Center | 2024 |
Greater mechanistic understanding of the cutaneous pathogenesis of Stevens–Johnson syndrome/toxic epidermal necrolysis can shed light on novel therapeutic strategies: a comprehensive review
Ogiji ED, Aboheimed N, Ross K, Voller C, Siner R, Jensen RL, Jolly CE, Carr DF |
Current Opinion in Allergy and Clinical Immunology | 2024 |
Single-cell RNA Sequencing Identifies Natural Kill Cell-Related Transcription Factors Associated With Age-Related Macular Degeneration
Luo Y, Liu J, Feng W, Lin D, Chen M, Zheng H |
Evolutionary Bioinformatics Online | 2024 |
Evaluating Ovarian Cancer Chemotherapy Response Using Gene Expression Data and Machine Learning.
Amniouel S, Yalamanchili K, Sankararaman S, Jafri MS |
BioMedInformatics | 2024 |
Polymeric PD1/PDL1 bispecific antibody enhances immune checkpoint blockade therapy
Xue F, Ren X, Kong C, Wang J, Liu L, Hu J, Shen N, Tang Z |
Materials Today Bio | 2024 |
Nasal mRNA Nanovaccine with Key Activators of Dendritic and MAIT Cells for Effective Against Lung Tumor Metastasis in Mice Model.
Li A, Cai X, Li D, Yu Y, Liu C, Shen J, You J, Qiao J, Wang F |
International journal of nanomedicine | 2024 |
Reprogramming of IL-12 secretion in the PDCD1 locus improves the anti-tumor activity of NY-ESO-1 TCR-T cells
Kim S, Park CI, Lee S, Choi HR, Kim CH |
Frontiers in immunology | 2023 |
Investigating the Effects of Olaparib on the Susceptibility of Glioblastoma Multiforme Tumour Cells to Natural Killer Cell-Mediated Responses
Moran J, Mylod E, Kane LE, Marion C, Keenan E, Mekhaeil M, Lysaght J, Dev KK, O\u2019Sullivan J, Conroy MJ |
Pharmaceutics | 2023 |
Preclinical development of a first-in-class vaccine encoding HER2, Brachyury and CD40L for antibody enhanced tumor eradication.
Hinterberger M, Endt K, Bathke B, Habjan M, Heiseke A, Schweneker M, Von Rohrscheidt J, Atay C, Chaplin P, Kalla M, Hausmann J, Schmittwolf C, Lauterbach H, Volkmann A, Hochrein H, Medina-Echeverz J |
Scientific Reports | 2023 |
Phenotypic and functional analysis in HER2+ targeted therapy of human NK cell subpopulation according to the expression of FcεRIγ and NKG2C in breast cancer patients.
Bordignon MB, Pesce Viglietti AI, Juliá EP, Sanchez MB, Rölle A, Mandó P, Sabatini L, Ostinelli A, Rizzo MM, Barrio MM, Mordoh J, Fainboim L, Levy EM |
Cancer Immunology, Immunotherapy | 2023 |
Interaction between Radiation Therapy and Targeted Therapies in HER2-Positive Breast Cancer: Literature Review, Levels of Evidence for Safety and Recommendations for Optimal Treatment Sequence
Debbi K, Grellier N, Loganadane G, Boukhobza C, Mahé M, Cherif MA, Rida H, Gligorov J, Belkacemi Y |
Cancers | 2023 |
Role of Cytokines and Growth Factors in the Manufacturing of iPSC-Derived Allogeneic Cell Therapy Products
Kao CY, Mills JA, Burke CJ, Morse B, Marques BF |
Biology | 2023 |
Viral nanoparticle vaccines against S100A9 reduce lung tumor seeding and metastasis.
Chung YH, Ortega-Rivera OA, Volckaert BA, Jung E, Zhao Z, Steinmetz NF |
Proceedings of the National Academy of Sciences | 2023 |
The nexus of natural killer cells and melanoma tumor microenvironment: crosstalk, chemotherapeutic potential, and innovative NK cell-based therapeutic strategies
Rahimi A, Malakoutikhah Z, Rahimmanesh I, Ferns GA, Nedaeinia R, Ishaghi SM, Dana N, Haghjooy Javanmard S |
Cancer Cell International | 2023 |
Recent Advancements in Antifibrotic Therapies for Regression of Liver Fibrosis
A Jangra, A Kothari, P Sarma, B Medhi, B Omar, K Kaushal |
Cells | 2022 |
A novel fusion protein scaffold 18/12/TxM activates the IL-12, IL-15, and IL-18 receptors to induce human memory-like natural killer cells
C Cubitt, E McClain, M Becker-Hapak, J Foltz, P Wong, J Wagner, C Neal, N Marin, L Marsala, M Foster, T Schappe, P Soon-Shiong, J Lee, M Berrien-Elliott, T Fehniger |
Molecular Therapy — Oncolytics | 2022 |
Cytokine Based Immunotherapy for Cancer and Lymphoma: Biology, Challenges and Future Perspectives
Atallah-Yunes SA, Robertson MJ |
Frontiers in immunology | 2022 |
Cellular Origins and Pathogenesis of Gastrointestinal NK- and T-Cell Lymphoproliferative Disorders
Hue SS, Ng SB, Wang S, Tan SY |
Cancers | 2022 |
Intratumoral delivery of dendritic cells plus anti-HER2 therapy triggers both robust systemic antitumor immunity and complete regression in HER2 mammary carcinoma
Ramamoorthi G, Kodumudi K, Snyder C, Grover P, Zhang H, Greene MI, Basu A, Gallen C, Wiener D, Costa RL, Han HS, Koski G, Czerniecki BJ |
Journal for ImmunoTherapy of Cancer | 2022 |
The balance of interleukin‐12 and interleukin‐23 determines the bias of MAIT1 versus MAIT17 responses during bacterial infection
Wang H, Nelson AG, Wang B, Zhao Z, Lim XY, Shi M, Meehan LJ, Jia X, Kedzierska K, Meehan BS, Eckle SB, Souter MN, Pediongco TJ, Mak JY, Fairlie DP, McCluskey J, Wang Z, Corbett AJ, Chen Z |
Immunology and Cell Biology | 2022 |
Antitumor Activities of Interleukin-12 in Melanoma
Gao W, Pan J, Pan J |
Cancers | 2022 |
TLR9 and Glioma: Friends or Foes?
Fehri E, Ennaifer E, Bel Haj Rhouma R, Ardhaoui M, Boubaker S |
Cells | 2022 |
Antibody Conjugation of Fluorescent Nanodiamonds for Targeted Innate Immune Cell Activation
LP Suarez-Kelly, SH Sun, C Ren, IV Rampersaud, D Albertson, MC Duggan, TC Noel, N Courtney, NJ Buteyn, C Moritz, L Yu, VO Yildiz, JP Butchar, S Tridandapani, AA Rampersaud, WE Carson |
2021 | |
Implications of a ‘Third Signal’ in NK Cells
M Khalil, D Wang, E Hashemi, SS Terhune, S Malarkannan |
Cells | 2021 |
The Role of Gut Microbiota in Overcoming Resistance to Checkpoint Inhibitors in Cancer Patients: Mechanisms and Challenges
Y Bouferraa, A Chedid, G Amhaz, AE Lakkiss, D Mukherji, S Temraz, A Shamseddine |
International journal of molecular sciences | 2021 |
Comparative Metabolomics Reveals the Microenvironment of Common T-Helper Cells and Differential Immune Cells Linked to Unique Periapical Lesions
AM Altaie, T Venkatachalam, LP Samaranayake, SS Soliman, R Hamoudi |
Frontiers in immunology | 2021 |
Tumor-Associated Macrophages in Pancreatic Ductal Adenocarcinoma: Therapeutic Opportunities and Clinical Challenges
AR Poh, M Ernst |
Cancers | 2021 |
Role of microRNAs in COVID-19 with implications for therapeutics
N Arghiani, T Nissan, MM Matin |
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie | 2021 |
Targeting ADCC: A different approach to HER2 breast cancer in the immunotherapy era
P Mandó, SG Rivero, MM Rizzo, M Pinkasz, EM Levy |
Breast (Edinburgh, Scotland) | 2021 |
Intranasal Administration of Codium fragile Polysaccharide Elicits Anti-Cancer Immunity against Lewis Lung Carcinoma
Y Wang, EK An, SJ Kim, SG You, JO Jin |
International journal of molecular sciences | 2021 |
Ebola virus triggers receptor tyrosine kinase-dependent signaling to promote the delivery of viral particles to entry-conducive intracellular compartments
CM Stewart, A Phan, Y Bo, ND LeBlond, TK Smith, G Laroche, PM Giguère, MD Fullerton, M Pelchat, D Kobasa, M Côté, JH Kuhn |
PLoS pathogens | 2021 |
Exploring the Emerging Role of the Gut Microbiota and Tumor Microenvironment in Cancer Immunotherapy
Q Qiu, Y Lin, Y Ma, X Li, J Liang, Z Chen, K Liu, Y Huang, H Luo, R Huang, L Luo |
Frontiers in immunology | 2021 |
Nanotechnology-enhanced immunotherapy for metastatic cancer
P Zhang, J Meng, Y Li, C Yang, Y Hou, W Tang, KJ McHugh, L Jing |
2021 | |
Defining the AHR-regulated transcriptome in NK cells reveals gene expression programs relevant to development and function
P Trikha, J Moseman, A Thakkar, A Campbell, E Elmas, J Foltz, N Chakravarti, J Fitch, E Mardis, D Lee |
Blood Advances | 2021 |
Increased IL-2 and Reduced TGF-β Upon T-Cell Stimulation are Associated with GM-CSF Upregulation in Multiple Immune Cell Types in Multiple Sclerosis
J Aram, N Frakich, E Morandi, M Alrouji, A Samaraweera, D Onion, I Spendlove, SL Colombo, R Tanasescu, B Gran, CS Constantinescu |
Biomedicines | 2020 |
Influence of the Tumor Microenvironment on NK Cell Function in Solid Tumors
O Melaiu, V Lucarini, L Cifaldi, D Fruci |
Frontiers in immunology | 2020 |
High-dose ascorbic acid synergizes with anti-PD1 in a lymphoma mouse model
RA Luchtel, T Bhagat, K Pradhan, WR Jacobs, M Levine, A Verma, N Shenoy |
Proceedings of the National Academy of Sciences | 2020 |
Clinical development of immunotherapies for HER2+ breast cancer: a review of HER2-directed monoclonal antibodies and beyond
RL Costa, BJ Czerniecki |
npj Breast Cancer | 2020 |
Mechanisms of Resistance to NK Cell Immunotherapy
C Sordo-Bahamonde, M Vitale, S Lorenzo-Herrero, A López-Soto, S Gonzalez |
Cancers | 2020 |
Gut Microbiome as a Potential Factor for Modulating Resistance to Cancer Immunotherapy
L Shui, , J Li, C Yi, Q Sun, H Zhu |
Frontiers in immunology | 2020 |
Oncolytic effects of the recombinant Newcastle disease virus, rAF-IL12, against colon cancer cells in vitro and in tumor-challenged NCr-Foxn1nu nude mice
SU Najmuddin, ZM Amin, SW Tan, SK Yeap, J Kalyanasundram, A Veerakumarasivam, SC Chan, SL Chia, K Yusoff, NB Alitheen |
PeerJ | 2020 |
Immunogenicity and antitumor efficacy of a novel human PD-1 B-cell vaccine (PD1-Vaxx) and combination immunotherapy with dual trastuzumab/pertuzumab-like HER-2 B-cell epitope vaccines (B-Vaxx) in a syngeneic mouse model
PT Kaumaya, L Guo, J Overholser, ML Penichet, T Bekaii-Saab |
OncoImmunology | 2020 |
Effect of interleukins (IL-2, IL-15, IL-18) on receptors activation and cytotoxic activity of natural killer cells in breast cancer cell
W Widowati, DK Jasaputra, SB Sumitro, MA Widodo, T Mozef, R Rizal, HS Kusuma, DR Laksmitawati, H Murti, I Bachtiar, A Faried |
African health sciences | 2020 |
CD16 pre-ligation by defucosylated tumor-targeting mAb sensitizes human NK cells to γc cytokine stimulation via PI3K/mTOR axis
C Capuano, C Pighi, R Maggio, S Battella, S Morrone, G Palmieri, A Santoni, C Klein, R Galandrini |
Cancer Immunology, Immunotherapy | 2020 |
Overcoming Resistance to Natural Killer Cell Based Immunotherapies for Solid Tumors
G Nayyar, Y Chu, MS Cairo |
Frontiers in Oncology | 2019 |
IL-27 promotes NK cell effector functions via Maf-Nrf2 pathway during influenza infection
P Kumar, K Rajasekaran, A Nanbakhsh, J Gorski, MS Thakar, S Malarkannan |
Scientific Reports | 2019 |
Amino acid residues involved in the heparin-binding activity of murine IL-12 in the context of an antibody-cytokine fusion protein
R Luria-Pérez, PV Candelaria, TR Daniels-Wells, JA Rodríguez, G Helguera, ML Penichet |
Cytokine | 2019 |
Soy isoflavones and their metabolites modulate cytokine-induced natural killer cell function
TA Mace, MB Ware, SA King, S Loftus, MR Farren, E McMichael, S Scoville, C Geraghty, G Young, WE Carson, SK Clinton, GB Lesinski |
Scientific Reports | 2019 |
A Phase I/II Trial of Cetuximab in Combination with Interleukin-12 Administered to Patients with Unresectable Primary or Recurrent Head and Neck Squamous Cell Carcinoma
EL McMichael, B Benner, LS Atwal, NB Courtney, X Mo, ME Davis, AR Campbell, MC Duggan, K Williams, K Martin, K Levine, GN Salavaggione, T Noel, A Ganju, S Uppati, B Paul, T Olencki, TN Teknos, P Savvides, S Tridandapani, JC Byrd, MA Caligiuri, SV Liu, WE Carson |
Clinical cancer research | 2019 |
Synergistic cancer immunotherapy combines MVA-CD40L induced innate and adaptive immunity with tumor targeting antibodies
J Medina-Echeverz, M Hinterberger, M Testori, M Geiger, R Giessel, B Bathke, R Kassub, F Gräbnitz, G Fiore, ST Wennier, P Chaplin, M Suter, H Hochrein, H Lauterbach |
Nature Communications | 2019 |
Nitric Oxide Production by Myeloid-Derived Suppressor Cells Plays a Role in Impairing Fc Receptor–Mediated Natural Killer Cell Function
A Stiff, P Trikha, B Mundy-Bosse, E McMichael, TA Mace, B Benner, K Kendra, A Campbell, S Gautam, D Abood, I Landi, V Hsu, M Duggan, R Wesolowski, M Old, JH Howard, L Yu, N Stasik, T Olencki, N Muthusamy, S Tridandapani, JC Byrd, M Caligiuri, WE Carson |
Clinical cancer research | 2018 |
FcγRIIIa-dependent IFN-γ release in whole blood assay is predictive of therapeutic IgG1 antibodies safety
NS Alakhras, J Qiu, GV Rocha, DR Witcher, A Koester, J You, DA Schaer, RB Holmgaard, K Driscoll, JA Willy, LP Malherbe |
mAbs | 2018 |
Heterodimeric Fc-fused IL12 shows potent antitumor activity by generating memory CD8 + T cells
K Jung, JH Ha, JE Kim, JA Kim, YJ Kim, CH Kim, YS Kim |
OncoImmunology | 2018 |
IL-15 Promotes Polyfunctional NK Cell Responses to Influenza by Boosting IL-12 Production
HR Wagstaffe, CM Nielsen, EM Riley, MR Goodier |
Journal of immunology (Baltimore, Md. : 1950) | 2018 |
Avelumab, an IgG1 anti-PD-L1 Immune Checkpoint Inhibitor, Triggers NK Cell-Mediated Cytotoxicity and Cytokine Production Against Triple Negative Breast Cancer Cells
EP Juliá, A Amante, MB Pampena, J Mordoh, EM Levy |
Frontiers in immunology | 2018 |
IL-15 enhanced antibody-dependent cellular cytotoxicity mediated by NK cells and macrophages
M Zhang, B Wen, OM Anton, Z Yao, S Dubois, W Ju, N Sato, DJ DiLillo, RN Bamford, JV Ravetch, TA Waldmann |
Proceedings of the National Academy of Sciences | 2018 |
Genomic and transcriptional Profiling of tumor infiltrated CD8 + T cells revealed functional heterogeneity of antitumor immunity in hepatocellular carcinoma
Z Li, G Chen, Z Cai, X Dong, L Qiu, H Xu, Y Zeng, X Liu, J Liu |
OncoImmunology | 2018 |
MICA-Expressing Monocytes Enhance Natural Killer Cell Fc Receptor-Mediated Antitumor Functions
AR Campbell, MC Duggan, LP Suarez-Kelly, N Bhave, KS Opheim, EL McMichael, P Trikha, R Parihar, E Luedke, A Lewis, B Yung, R Lee, D Raulet, S Tridandapani, V Groh, L Yu, V Yildiz, JC Byrd, MA Caligiuri, WE Carson |
Cancer immunology research | 2017 |
Natural Killer Cells - Their Role in Tumour Immunosurveillance
P Sharma |
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH | 2017 |
Tocilizumab (Anti-IL-6R) Suppressed TNFα Production by Human Monocytes in an In Vitro Model of Anti-HLA Antibody-Induced Antibody-Dependent Cellular Cytotoxicity:
BH Shin, S Ge, J Mirocha, SC Jordan, M Toyoda |
Transplantation Direct | 2017 |
Activation of the FcgammaReceptorIIIa on human natural killer cells leads to increased expression of functional interleukin-21 receptor
EL McMichael, NB Courtney, MC Duggan, R Wesolowski, D Quiroga, SV Kondadasula, LS Atwal, N Bhave, E Luedke, AC Jaime-Ramirez, AR Campbell, X Mo, JC Byrd, WE Carson |
OncoImmunology | 2017 |
Patient’s Natural Killer Cells in the Era of Targeted Therapies: Role for Tumor Killers
M Messaoudene, A Frazao, PJ Gavlovsky, A Toubert, N Dulphy, A Caignard |
Frontiers in immunology | 2017 |
Co-stimulation of the Fc receptor and Interleukin-12 receptor on human natural killer cells leads to increased expression of CD25
MC Duggan, AR Campbell, EL McMichael, KS Opheim, KM Levine, N Bhave, MC Culbertson, T Noel, L Yu, WE Carson |
OncoImmunology | 2017 |
Interplay between Natural Killer Cells and Anti-HER2 Antibodies: Perspectives for Breast Cancer Immunotherapy
A Muntasell, M Cabo, S Servitja, I Tusquets, M Martínez-García, A Rovira, F Rojo, J Albanell, M López-Botet |
Frontiers in immunology | 2017 |
Modulation of Innate Immunity by lignin-Carbohydrate, a Novel TLR4 Ligand, Results in Augmentation of Mucosal IgA and Systemic IgG Production
R Tsuji, K Ikado, D Fujiwara |
International journal of molecular sciences | 2017 |
NK Cell-Mediated Antitumor Effects of a Folate-Conjugated Immunoglobulin Are Enhanced by Cytokines
AC Jaime-Ramirez, EL McMichael, S Kondadasula, CC Skinner, BL Mundy-Bosse, E Luedke, NB Jones, A Mani, J Roda, V Karpa, H Li, J Li, S Elavazhagan, KM la Perle, AC Schmitt, Y Lu, X Zhang, X Pan, H Mao, M Davis, D Jarjoura, JP Butchar, M Poi, M Phelps, S Tridandapani, JC Byrd, MA Caligiuri, RJ Lee, WE Carson |
Cancer immunology research | 2016 |
Folate-conjugated immunoglobulin targets melanoma tumor cells for NK cell effector functions:
CC Skinner, EL McMichael, AC Jaime-Ramirez, ZB Abrams, RJ Lee, WE Carson |
Melanoma Research | 2016 |
Antitumor Activity of cGAMP via Stimulation of cGAS-cGAMP-STING-IRF3 Mediated Innate Immune Response
T Li, H Cheng, H Yuan, Q Xu, C Shu, Y Zhang, P Xu, J Tan, Y Rui, P Li, X Tan |
Scientific Reports | 2016 |
Fluorescent nanodiamonds engage innate immune effector cells: A potential vehicle for targeted anti-tumor immunotherapy
LP Suarez-Kelly, AR Campbell, IV Rampersaud, A Bumb, MS Wang, JP Butchar, S Tridandapani, L Yu, AA Rampersaud, WE Carson |
Nanomedicine: Nanotechnology, Biology and Medicine | 2016 |
IL-21 Enhances Natural Killer Cell Response to Cetuximab-Coated Pancreatic Tumor Cells
EL McMichael, AC Jaime-Ramirez, KD Guenterberg, E Luedke, LS Atwal, AR Campbell, Z Hu, AS Tatum, SV Kondadasula, X Mo, S Tridandapani, M Bloomston, EC Ellison, TM Williams, T Bekaii-Saab, WE Carson |
Clinical cancer research | 2016 |
A Phase I Trial to Evaluate Antibody-Dependent Cellular Cytotoxicity of Cetuximab and Lenalidomide in Advanced Colorectal and Head and Neck Cancer
EM Bertino, EL McMichael, X Mo, P Trikha, M Davis, B Paul, M Grever, WE Carson, GA Otterson |
Molecular cancer therapeutics | 2016 |
Balance of cellular and humoral immunity determines the level of protection by HIV vaccines in rhesus macaque models of HIV infection
TR Fouts, K Bagley, IJ Prado, KL Bobb, JA Schwartz, R Xu, RJ Zagursky, MA Egan, JH Eldridge, CC LaBranche, DC Montefiori, HL Buanec, D Zagury, R Pal, GN Pavlakis, BK Felber, G Franchini, S Gordon, M Vaccari, GK Lewis, AL DeVico, RC Gallo |
Proceedings of the National Academy of Sciences | 2015 |
An Fc engineering approach that modulates antibody-dependent cytokine release without altering cell-killing functions
M Kinder, AR Greenplate, WR Strohl, RE Jordan, RJ Brezski |
mAbs | 2015 |
Adjuvant cellular immunotherapy in patients with resected primary non-small cell lung cancer
QZ Pan, Y Tang, QJ Wang, YQ Li, L Zhang, XD Li, JJ Zhao, DS Weng, Q Liu, LX Huang, J He, SP Chen, ML Ke, YX Zeng, JC Xia |
OncoImmunology | 2015 |
The Raf Kinase Inhibitor Sorafenib Inhibits JAK-STAT Signal Transduction in Human Immune Cells
SE Campo, KM Levine, BL Mundy-Bosse, VP Grignol, ET Fairchild, AR Campbell, P Trikha, TA Mace, BK Paul, AC Jaime-Ramirez, J Markowitz, SV Kondadasula, KD Guenterberg, S McClory, VI Karpa, X Pan, TE Olencki, JP Monk, A Mortazavi, S Tridandapani, GB Lesinski, JC Byrd, MA Caligiuri, MH Shah, WE Carson |
Journal of immunology (Baltimore, Md. : 1950) | 2015 |
Analysis of in vitro ADCC and clinical response to trastuzumab: possible relevance of FcγRIIIA/FcγRIIA gene polymorphisms and HER-2 expression levels on breast cancer cell lines
S Boero, A Morabito, B Banelli, B Cardinali, B Dozin, G Lunardi, P Piccioli, S Lastraioli, R Carosio, S Salvi, A Levaggi, F Poggio, A DAlonzo, M Romani, LD Mastro, A Poggi, MP Pistillo |
Journal of Translational Medicine | 2015 |
Gene expression profiling of the human natural killer cell response to Fc receptor activation: unique enhancement in the presence of interleukin-12
AR Campbell, K Regan, N Bhave, A Pattanayak, R Parihar, AR Stiff, P Trikha, SD Scoville, S Liyanarachchi, SV Kondadasula, O Lele, R Davuluri, PR Payne, WE Carson |
BMC Medical Genomics | 2015 |
Clinical utility of natural killer cells in cancer therapy and transplantation
DA Knorr, V Bachanova, MR Verneris, JS Miller |
Seminars in Immunology | 2014 |
Interleukin 12: still a promising candidate for tumor immunotherapy?
W Lasek, R Zagożdżon, M Jakobisiak |
Cancer Immunology, Immunotherapy | 2014 |
Utilizing cytokines to function-enable human NK cells for the immunotherapy of cancer
R Romee, JW Leong, TA Fehniger |
Scientifica | 2014 |
Genkwadaphnin Induces IFN-γ via PKD1/NF-κB/STAT1 Dependent Pathway in NK-92 Cells
HB Kang, KS Ahn, SR Oh, JW Kim, QJ Wang |
PloS one | 2014 |
Cetuximab-activated natural killer and dendritic cells collaborate to trigger tumor antigen-specific T-cell immunity in head and neck cancer patients
RM Srivastava, SC Lee, PA Filho, CA Lord, HB Jie, HC Davidson, A López-Albaitero, SP Gibson, WE Gooding, S Ferrone, RL Ferris |
Clinical cancer research | 2013 |
Toll-like receptor 2 ligands regulate monocyte Fcγ receptor expression and function
P Shah, K Fatehchand, H Patel, H Fang, SE Justiniano, X Mo, D Jarjoura, S Tridandapani, JP Butchar |
The Journal of biological chemistry | 2013 |
Gene Expression Meta-Analysis Identifies Cytokine Pathways and 5q Aberrations Involved in Metastasis of ERBB2 Amplified and Basal Breast Cancer
M Thomassen, Q Tan, M Burton, TA Kruse |
Cancer informatics | 2013 |
Effects of interleukin-18 on natural killer cells: costimulation of activation through Fc receptors for immunoglobulin
S Srivastava, D Pelloso, H Feng, L Voiles, D Lewis, Z Haskova, M Whitacre, S Trulli, YJ Chen, J Toso, ZL Jonak, HC Chang, MJ Robertson |
Cancer Immunology, Immunotherapy | 2013 |
NK cell-based immunotherapy for malignant diseases
M Cheng, Y Chen, W Xiao, R Sun, Z Tian |
Cellular and Molecular Immunology | 2013 |
The marginating-pulmonary immune compartment in mice exhibits increased NK cytotoxicity and unique cellular characteristics
M Benish, R Melamed, E Rosenne, E Neeman, L Sorski, B Levi, L Shaashua, P Matzner, S Ben-Eliyahu |
Immunologic Research | 2013 |
The use of lentinan for treating gastric cancer.
Ina K, Kataoka T, Ando T |
Anti-cancer agents in medicinal chemistry | 2013 |
Super-resolution imaging of remodeled synaptic actin reveals different synergies between NK cell receptors and integrins
AC Brown, IM Dobbie, JM Alakoskela, I Davis, DM Davis |
Blood | 2012 |
Monoclonal antibody therapy of pancreatic cancer with cetuximab: potential for immune modulation
E Luedke, AC Jaime-Ramirez, N Bhave, WE 3rd |
Journal of immunotherapy (Hagerstown, Md. : 1997) | 2012 |
Combination strategies to enhance antitumor ADCC
HE Kohrt, R Houot, A Marabelle, HJ Cho, K Osman, M Goldstein, R Levy, J Brody |
Immunotherapy | 2012 |
Bispecific and trispecific killer cell engagers directly activate human NK cells through CD16 signaling and induce cytotoxicity and cytokine production
MK Gleason, MR Verneris, DA Todhunter, B Zhang, V McCullar, SX Zhou, A Panoskaltsis-Mortari, LM Weiner, DA Vallera, JS Miller |
Molecular cancer therapeutics | 2012 |
miR-155 regulates IFN-γ production in natural killer cells
R Trotta, L Chen, D Ciarlariello, S Josyula, C Mao, S Costinean, L Yu, JP Butchar, S Tridandapani, CM Croce, MA Caligiuri |
Blood | 2012 |
Cetuximab therapy in head and neck cancer: Immune modulation with interleukin-12 and other natural killer cell–activating cytokines
E Luedke, AC Jaime-Ramirez, N Bhave, J Roda, MM Choudhary, B Kumar, TN Teknos, WE Carson |
Surgery | 2012 |
Anti-cancer immune response mechanisms in neoadjuvant and targeted therapy
C Denkert, S Darb-Esfahani, S Loibl, I Anagnostopoulos, K Jöhrens |
Seminars in Immunopathology | 2011 |
Clinical cancer therapy by NK cells via antibody-dependent cell-mediated cytotoxicity
KL Alderson, PM Sondel |
Journal of biomedicine & biotechnology | 2011 |
T-bet expression in intratumoral lymphoid structures after neoadjuvant trastuzumab plus docetaxel for HER2-overexpressing breast carcinoma predicts survival
S Ladoire, L Arnould, G Mignot, L Apetoh, C Rébé, F Martin, P Fumoleau, B Coudert, F Ghiringhelli |
British Journal of Cancer | 2011 |
TLR2 agonist PSK activates human NK cells and enhances the antitumor effect of HER2-targeted monoclonal antibody therapy
H Lu, Y Yang, E Gad, C Inatsuka, CA Wenner, ML Disis, LJ Standish |
Clinical cancer research | 2011 |
Use of a nanoporous biodegradable miniature device to regulate cytokine release for cancer treatment
H He, V Grignol, V Karpa, C Yen, K LaPerle, X Zhang, NB Jones, MI Liang, GB Lesinski, WS Ho, WE Carson, LJ Lee |
Journal of Controlled Release | 2011 |
Helper Activity of Natural Killer Cells During the Dendritic Cell-mediated Induction of Melanoma-specific Cytotoxic T Cells:
JL Wong, RB Mailliard, SJ Moschos, H Edington, MT Lotze, JM Kirkwood, P Kalinski |
Journal of immunotherapy (Hagerstown, Md. : 1997) | 2011 |
IL-12 Enhances the Antitumor Actions of Trastuzumab via NK Cell IFN-γ Production
AC Jaime-Ramirez, BL Mundy-Bosse, SV Kondadasula, NB Jones, JM Roda, A Mani, R Parihar, V Karpa, TL Papenfuss, KM LaPerle, E Biller, A Lehman, AR Chaudhury, D Jarjoura, RW Burry, WE Carson |
Journal of immunology (Baltimore, Md. : 1950) | 2011 |
Immune therapy for breast cancer in 2010—hype or hope?
Florescu A, Amir E, Bouganim N, Clemons M |
Current Oncology | 2011 |
CD19 targeting of chronic lymphocytic leukemia with a novel Fc-domain-engineered monoclonal antibody
FT Awan, R Lapalombella, R Trotta, JP Butchar, B Yu, DM Benson, JM Roda, C Cheney, X Mo, A Lehman, J Jones, J Flynn, D Jarjoura, JR Desjarlais, S Tridandapani, MA Caligiuri, N Muthusamy, JC Byrd |
Blood | 2010 |
A multiscale systems perspective on cancer, immunotherapy, and Interleukin-12
DJ Klinke |
Molecular Cancer | 2010 |
Curcumin induces proapoptotic effects against human melanoma cells and modulates the cellular response to immunotherapeutic cytokines
MA Bill, C Bakan, DM Benson, J Fuchs, G Young, GB Lesinski |
Molecular cancer therapeutics | 2009 |
Gene expression profiling reveals similarities between the in vitro and in vivo responses of immune effector cells to IFN-alpha
JM Zimmerer, GB Lesinski, AS Ruppert, MD Radmacher, C Noble, K Kendra, MJ Walker, WE 3rd |
Clinical cancer research | 2008 |
Human natural killer cells
MA Caligiuri |
Blood | 2008 |
Rafting with the IL-12 receptor
DW McVicar |
Blood | 2008 |
Maturation of monocyte-derived dendritic cells with Toll-like receptor 3 and 7/8 ligands combined with prostaglandin E2 results in high interleukin-12 production and cell migration
AC Boullart, EH Aarntzen, P Verdijk, JF Jacobs, DH Schuurhuis, D Benitez-Ribas, G Schreibelt, MW van de Rakt, NM Scharenborg, A Boer, M Kramer, CG Figdor, CJ Punt, GJ Adema, IJ de Vries |
Cancer Immunology, Immunotherapy | 2008 |
Colocalization of the IL-12 receptor and FcgammaRIIIa to natural killer cell lipid rafts leads to activation of ERK and enhanced production of interferon-gamma
SV Kondadasula, JM Roda, R Parihar, J Yu, A Lehman, MA Caligiuri, S Tridandapani, RW Burry, WE 3rd |
Blood | 2008 |
A phase II trial of trastuzumab in combination with low-dose interleukin-2 (IL-2) in patients (PTS) with metastatic breast cancer (MBC) who have previously failed trastuzumab
A Mani, J Roda, D Young, MA Caligiuri, GF Fleming, P Kaufman, A Brufsky, S Ottman, WE Carson, CL Shapiro |
Breast Cancer Research and Treatment | 2008 |
TGF-β Utilizes SMAD3 to Inhibit CD16-Mediated IFN-γ Production and Antibody-Dependent Cellular Cytotoxicity in Human NK Cells
Trotta R, Col JD, Yu J, Ciarlariello D, Thomas B, Zhang X, Allard J II, Wei M, Mao H, Byrd JC, Perrotti D, Caligiuri MA |
Journal of immunology (Baltimore, Md. : 1950) | 2008 |
Biology and clinical impact of human natural killer cells
SS Farag, JB VanDeusen, TA Fehniger, MA Caligiuri |
International Journal of Hematology | 2003 |