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SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

Jay D. Horton, … , Joseph L. Goldstein, Michael S. Brown

Jay D. Horton, … , Joseph L. Goldstein, Michael S. Brown

Published May 1, 2002
Citation Information: J Clin Invest. 2002;109(9):1125-1131. https://doi.org/10.1172/JCI15593.

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VHL mutation drives human clear cell renal cell carcinoma progression through PI3K/AKT-dependent cholesteryl ester accumulation. Zhang S, Fang T, He Y, Feng W, Yu Z, Zheng Y, Zhang C, Hu S, Liu Z, Liu J, Yu J, Zhang H, He A, Gong Y, He Z, Yang K, Xi Z, Yu W, Zhou L, Yao L, Yue S	EBioMedicine	2024
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The Human Milk Oligosaccharide 3’Sialyllactose Reduces Low-grade Inflammation and Atherosclerosis Development in Mice. Ariane Pessentheiner, Nathanael Spann, Chloe A. Autran, Tae Oh, Kaare Grunddal, Joanna Coker, Chelsea D Painter, Bastian Ramms, Austin Chiang, Chen-Yi Wang, Jason Hsiao, Yiwen Wang, Anthony Quach, Laela M. Booshehri, Alexandra Hammond, Chiara Tognaccini, Joanna Latasiewicz, Lisa Willemsen, Karsten Zengler, Menno Winther, Hal Hoffman, Martin Philpott, Adam Cribbs, Udo Oppermann, Nathan Lewis, Joseph Witztum, Ruth Yu, Annette Atkins, Michael Downes, Ronald Evans, Christopher Glass, Lars Bode, Philip Gordts	JCI insight	2024
Oroxin A from Oroxylum indicum improves disordered lipid metabolism by inhibiting SREBPs in oleic acid-induced HepG2 cells and high-fat diet-fed non-insulin-resistant rats Cai T, Xu X, Dong L, Liang S, Xin M, Wang T, Li T, Wang X, Zheng W, Wang C, Xu Z, Wang M, Song X, Li L, Li J, Sun W	Heliyon	2024
Crosstalk between lipid metabolism and EMT: emerging mechanisms and cancer therapy. Din ZU, Cui B, Wang C, Zhang X, Mehmood A, Peng F, Liu Q	Molecular and Cellular Biochemistry	2024
Induction of hepatic CYP3A4 expression by cholesterol and cholic acid: Alterations of gene expression, microsomal activity, and pharmacokinetics Minegishi G, Kobayashi Y, Fujikura M, Sano A, Kazuki Y, Kobayashi K	Pharmacology Research & Perspectives	2024
The Role of PNPLA3_rs738409 Gene Variant, Lifestyle Factors, and Bioactive Compounds in Nonalcoholic Fatty Liver Disease: A Population-Based and Molecular Approach towards Healthy Nutrition Liu M, Park S	Nutrients	2024
High Starch Induces Hematological Variations, Metabolic Changes, Oxidative Stress, Inflammatory Responses, and Histopathological Lesions in Largemouth Bass (Micropterus salmoides) Xie Y, Shao X, Zhang P, Zhang H, Yu J, Yao X, Fu Y, Wei J, Wu C	Metabolites	2024
Upregulated Matrisomal Proteins and Extracellular Matrix Mechanosignaling Underlie Obesity-Associated Promotion of Pancreatic Ductal Adenocarcinoma Waldron RT, Lugea A, Chang HH, Su HY, Quiros C, Lewis MS, Che M, Ramanujan VK, Rozengurt E, Eibl G, Pandol SJ	Cancers	2024
Zebrafish cobll1a regulates lipid homeostasis via the RA signaling pathway Zeng T, Lv J, Liang J, Xie B, Liu L, Tan Y, Zhu J, Jiang J, Xie H	Frontiers in Cell and Developmental Biology	2024
Flavonoids regulate LDLR through different mechanisms tied to their specific structures Bjune K, Halvorsen PS, Wangensteen H, Leren TP, Bogsrud MP, Strøm TB	Journal of lipid research	2024
Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD Pineda SS, Lee H, Ulloa-Navas MJ, Linville RM, Garcia FJ, Galani K, Engelberg-Cook E, Castanedes MC, Fitzwalter BE, Pregent LJ, Gardashli ME, DeTure M, Vera-Garcia DV, Hucke AT, Oskarsson BE, Murray ME, Dickson DW, Heiman M, Belzil VV, Kellis M	Cell	2024
Dual Deletion of Keap1 and Rbpjκ Genes in Liver Leads to Hepatomegaly and Hypercholesterolemia Wakabayashi N, Yagishita Y, Joshi T, Kensler TW	International journal of molecular sciences	2024
Future therapeutic perspectives in nonalcoholic fatty liver disease: a focus on nuclear receptors, a promising therapeutic target Stan SI, Biciuşcă V, Clenciu D, Mitrea A, Boldeanu MV, Durand P, Dănoiu S	Medicine and pharmacy reports	2024
The impact of sericin on inflammation, oxidative stress, and lipid metabolism in female rats with experimental knee osteoarthritis. Gundogdu G, Kilic-Erkek O, Gundogdu K	Clinical Rheumatology	2024
SPRING is a Dedicated Licensing Factor for SREBP-Specific Activation by S1P. Hendrix S, Tan JME, Ndoj K, Kingma J, Valiloo M, Zijlstra LF, Ottenhoff R, Seidah NG, Loregger A, Kober DL, Zelcer N	Molecular and cellular biology	2024
Polyphyllin I induces rapid ferroptosis in acute myeloid leukemia through simultaneous targeting PI3K/SREBP-1/SCD1 axis and triggering of lipid peroxidation. Zhou X, Zhang D, Lei J, Ren J, Yang B, Cao Z, Guo C, Li Y	Journal of Natural Medicines	2024
C9orf72 controls hepatic lipid metabolism by regulating SREBP1 transport. Wu Y, Zheng W, Xu G, Zhu L, Li Z, Chen J, Wang L, Chen S	Cell Death and Differentiation	2024
Effects of emulsifiers on lipid metabolism and performance of yellow-feathered broilers Wang Y, Zeng D, Wei L, Chen J, Li H, Wen L, Huang G, Dai Z, Luo J, Sun J, Xi Q, Zhang Y, Chen T	BMC veterinary research	2024
Alzheimer’s disease risk allele of PICALM causes detrimental lipid droplets in microglia Kozlova A, Zhang S, Sudwarts A, Zhang H, Smirnou S, Sun X, Stephenson K, Zhao X, Jamison B, Ponnusamy M, He X, Pang ZP, Sanders AR, Bellen HJ, Thinakaran G, Duan J	Research square	2024
Mitochondrial lipidomes are tissue specific – low cholesterol contents relate to UCP1 activity Brunner S, Höring M, Liebisch G, Schweizer S, Scheiber J, Giansanti P, Hidrobo M, Hermeling S, Oeckl J, Prudente de Mello N, Perocchi F, Seeliger C, Strohmeyer A, Klingenspor M, Plagge J, Küster B, Burkhardt R, Janssen KP, Ecker J	Life science alliance	2024
Identification of proteins related to SIS3 by iTRAQ and PRM-based comparative proteomic analysis in cisplatin-induced acute kidney injury Huang J, Ye J, Gao Y, Wang Y, Zhao Q, Lou T, Lai W	PeerJ	2024
Navigating the Maze of Kinases: CaMK-like Family Protein Kinases and Their Role in Atherosclerosis Teuwen JT, van der Vorst EP, Maas SL	International journal of molecular sciences	2024
High-fat diet induced obesity promotes inflammation, oxidative stress, and hepatotoxicity in female FVB/N mice Ofosu-Boateng M, Shaik F, Choi S, Ekuban FA, Gebreyesus LH, Twum E, Nnamani D, Yeyeodu ST, Yadak N, Collier DM, Gyamfi MA	BioFactors (Oxford, England)	2024
The key role of altered tubule cell lipid metabolism in kidney disease development Lee LE, Doke T, Mukhi D, Susztak K	Kidney International	2024
Positive Effects of Physical Activity on Insulin Signaling Małkowska P	Current issues in molecular biology	2024
Unraveling the intricate relationship between lipid metabolism and oncogenic signaling pathways Khan F, Elsori D, Verma M, Pandey S, Obaidur Rab S, Siddiqui S, Alabdallah NM, Saeed M, Pandey P	Frontiers in Cell and Developmental Biology	2024
Jingzhi Guanxin Oral Liquids Attenuate Atherosclerotic Coronary Heart Disease via Modulating Lipid Metabolism and PPAR-Related Targets Wang X, Hu T, Jiang Y, He Y, Li P, Peng W, Wang Y, Su W	Pharmaceuticals	2024
Low-Iron Diet-Induced Fatty Liver Development Is Microbiota Dependent and Exacerbated by Loss of the Mitochondrial Iron Importer Mitoferrin2 Klag KA, Bell R, Jia X, Seguin A, Maschek JA, Bronner M, Cox JE, Round JL, Ward DM	Nutrients	2024
Elucidating the Role of Lipid-Metabolism-Related Signal Transduction and Inhibitors in Skin Cancer Kook E, Kim DH	Metabolites	2024
In vivo CRISPR screening identifies geranylgeranyl diphosphate as a pancreatic cancer tumor growth dependency Kubota CS, Myers SL, Seppälä TT, Burkhart RA, Espenshade PJ	Molecular Metabolism	2024
The Long Non‐Coding RNA Obesity‐Related (Obr) Contributes To Lipid Metabolism Through Epigenetic Regulation Kaimala S, Lootah SS, Mehra N, Kumar CA, Marzooqi SA, Sampath P, Ansari SA, Emerald BS	Advanced Science	2024
Pea Albumin Extracted from Pea (Pisum sativum L.) Seeds Ameliorates High-Fat-Diet-Induced Non-Alcoholic Fatty Liver Disease by Regulating Lipogenesis and Lipolysis Pathways. Zhang S, Cui Z, Zhang H, Wang P, Wang F, Zhang J	Nutrients	2024
Signaling through the nicotinic acetylcholine receptor in the liver protects against the development of metabolic dysfunction-associated steatohepatitis Jun H, Liu S, Knights AJ, Zhu K, Ma Y, Gong J, Lenhart AE, Peng X, Huang Y, Ginder JP, Downie CH, Ramos ET, Kullander K, Kennedy RT, Xu XZ, Wu J	PLoS Biology	2024
Hyperactivation of SREBP induces pannexin-1-dependent lytic cell death Xiong Y, Luo J, Hong ZY, Zhu WZ, Hu A, Song BL	Journal of lipid research	2024
Lipid homeostasis in diabetic kidney disease Wang Y, Liu T, Wu Y, Wang L, Ding S, Hou B, Zhao H, Liu W, Li P	International journal of biological sciences	2024
Human cytomegalovirus infection impairs neural differentiation via repressing sterol regulatory element binding protein 2-mediated cholesterol biosynthesis. Li J, Sun J, Xu M, Yang L, Yang N, Deng J, Ma Y, Qi Y, Liu Z, Ruan Q, Liu Y, Huang Y	Cellular and molecular life sciences : CMLS	2024
Arachidonic Acid Mobilization and Peroxidation Promote Microglial Dysfunction in Aβ Pathology. Lin D, Gold A, Kaye S, Atkinson JR, Tol M, Sas A, Segal B, Tontonoz P, Zhu J, Gao J	The Journal of neuroscience : the official journal of the Society for Neuroscience	2024
Effects of Tea Seed Oil Extracted by Different Refining Temperatures on the Intestinal Microbiota of High-Fat-Diet-Induced Obese Mice Chen L, Jiang Q, Lu H, Jiang C, Hu W, Liu H, Xiang X, Tan CP, Zhou T, Shen G	Foods (Basel, Switzerland)	2024
Unraveling cysteine deficiency-associated rapid weight loss. Varghese A, Gusarov I, Gamallo-Lana B, Dolgonos D, Mankan Y, Shamovsky I, Phan M, Jones R, Gomez-Jenkins M, White E, Wang R, Jones D, Papagiannakopoulos T, Pacold ME, Mar AC, Littman DR, Nudler E	bioRxiv : the preprint server for biology	2024
Coffee pulp improves glucose and lipid metabolism disorder in high-fat diet-induced diabetic mice Zhu S, Wang C, Meng ZX	Metabolism Open	2024
Phosphorylation of Insig-2 mediates inhibition of fatty acid synthesis by polyunsaturated fatty acids Tian J, Goldstein JL, Li S, Schumacher MM, Brown MS	Proceedings of the National Academy of Sciences of the United States of America	2024
Polyphenols alleviate metabolic disorders: the role of ubiquitin-proteasome system Gu W, Wu G, Chen G, Meng X, Xie Z, Cai S	Frontiers in Nutrition	2024
Imeglimin enhances glucagon secretion through an indirect mechanism and improves fatty liver in high‐fat, high‐sucrose diet‐fed mice Kikuchi O, Ikeuchi Y, Kobayashi M, Tabei Y, Yokota\u2010Hashimoto H, Kitamura T	Journal of Diabetes Investigation	2024
Research progress of SREBP and its role in the pathogenesis of autoimmune rheumatic diseases Xu X, Jin W, Chang R, Ding X	Frontiers in Immunology	2024
Cholesterol Metabolism and Urinary System Tumors Yang S, Ye Z, Ning J, Wang P, Zhou X, Li W, Cheng F	Biomedicines	2024
LXR-dependent enhancer activation regulates the temporal organization of the liver’s response to refeeding leading to lipogenic gene overshoot Korenfeld N, Gorbonos T, Romero Florian MC, Rotaro D, Goldberg D, Radushkevitz-Frishman T, Charni-Natan M, Bar-Shimon M, Cummins CL, Goldstein I	PLOS Biology	2024
Knockouts of CYP51A1, DHCR24, or SC5D from cholesterol synthesis reveal pathways modulated by sterol intermediates Skubic C, Trček H, Nassib P, Kreft T, Walakira A, Pohar K, Petek S, Režen T, Ihan A, Rozman D	iScience	2024
Mechanism of Obesity-Related Lipotoxicity and Clinical Perspective. Engin AB	Advances in experimental medicine and biology	2024
CTBP1 links metabolic syndrome to polycystic ovary syndrome through interruption of aromatase and SREBP1. Kong Y, Yang G, Feng X, Ji Z, Wang X, Shao Y, Meng J, Yao G, Ren C, Yang G	Communications biology	2024
Association between substituting macronutrients and all-cause mortality: a network meta-analysis of prospective observational studies. Wallerer S, Papakonstantinou T, Morze J, Stadelmaier J, Kiesswetter E, Gorenflo L, Barbaresko J, Szczerba E, Neuenschwander M, Bell W, Kühn T, Lohner S, Guasch-Ferré M, Hoffmann G, Meerpohl JJ, Schlesinger S, Nikolakopoulou A, Schwingshackl L	EClinicalMedicine	2024
Effects of Propolis Consumption on Liver Enzymes and Obesity Indices in Adults: A Systematic Review and Dose-Response Meta-Analysis. Aliakbarian M, Jazinaki MS, Bahari H, Rashidmayvan M, Golafrouz H, Khodashahi R, Pahlavani N	Current developments in nutrition	2024
A suite of genome-engineered hepatic cells provides novel insights into the spatiotemporal metabolism of apolipoprotein B and apolipoprotein B–containing lipoprotein secretion Meurs A, Ndoj K, van den Berg M, Marinković G, Tantucci M, Veenendaal T, Kuivenhoven JA, Klumperman J, Zelcer N	Cardiovascular Research	2024
Schisanhenol ameliorates non-alcoholic fatty liver disease via inhibiting miR-802 activation of AMPK-mediated modulation of hepatic lipid metabolism Li B, Xiao Q, Zhao H, Zhang J, Yang C, Zou Y, Zhang B, Liu J, Sun H, Liu H	Acta Pharmaceutica Sinica. B	2024
Antidiabetic and Antihyperlipidemic Activities and Molecular Mechanisms of Phyllanthus emblica L. Extract in Mice on a High-Fat Diet Lin HY, Lin CH, Kuo YH, Shih CC	Current Issues in Molecular Biology	2024
Chrysomycin A Reshapes Metabolism and Increases Oxidative Stress to Hinder Glioblastoma Progression Liu DN, Zhang WF, Feng WD, Xu S, Feng DH, Song FH, Zhang HW, Fang LH, Du GH, Wang YH	Marine Drugs	2024
Nickel tolerance is channeled through C-4 methyl sterol oxidase Erg25 in the sterol biosynthesis pathway Matha AR, Xie X, Maier RJ, Lin X	PLOS Genetics	2024
Cholesterol promotes IFNG mRNA expression in CD4+ effector/memory cells by SGK1 activation Hanin A, Comi M, Sumida TS, Hafler DA	Life Science Alliance	2024
Inhibition of hepatic oxalate overproduction ameliorates metabolic dysfunction-associated steatohepatitis. Das S, Finney AC, Anand SK, Rohilla S, Liu Y, Pandey N, Ghrayeb A, Kumar D, Nunez K, Liu Z, Arias F, Zhao Y, Pearson-Gallion BH, McKinney MP, Richard KSE, Gomez-Vidal JA, Abdullah CS, Cockerham ED, Eniafe J, Yurochko AD, Magdy T, Pattillo CB, Kevil CG, Razani B, Bhuiyan MS, Seeley EH, Galliano GE, Wei B, Tan L, Mahmud I, Surakka I, Garcia-Barrio MT, Lorenzi PL, Gottlieb E, Salido E, Zhang J, Orr AW, Liu W, Diaz-Gavilan M, Chen YE, Dhanesha N, Thevenot PT, Cohen AJ, Yurdagul A Jr, Rom O	Nature metabolism	2024
Dietary supplementation of poly-dihydromyricetin-fused zinc nanoparticles alleviates fatty liver hemorrhagic syndrome by improving antioxidant capacity, intestinal health and lipid metabolism of laying hens. Yang Y, Shu X, Javed HU, Wu Q, Liu H, Han J, Zhou H	Poultry science	2024
Molecular mechanism of ectopic lipid accumulation induced by methylglyoxal via activation of the NRF2/PI3K/AKT pathway implicates renal lipotoxicity caused by diabetes mellitus. Peng CC, Chen ECY, Chen CR, Chyau CC, Chen KC, Peng RY	PloS one	2024
PAK3 Exacerbates Cardiac Lipotoxicity via SREBP1c in Obesity Cardiomyopathy Chen X, Ruiz-Velasco A, Zou Z, Hille SS, Ross C, Fonseka O, Gare SR, Alatawi NH, Raja R, Zhang J, Kaur N, Zhao X, Morrell-Davies H, Miller JM, Abouleisa RR, Ou Q, Frank D, Rutter MK, Pinali C, Wang T, Mohamed TM, Müller OJ, Liu W	Diabetes	2024
Oxidative Stress, Inflammation, and Altered Lymphocyte E-NTPDase Are Implicated in Acute Dyslipidemia in Rats: Protective Role of Arbutin. Alruhaimi RS, Hussein OE, Alnasser SM, Germoush MO, Alotaibi M, Hassanein EHM, El Mohtadi M, Mahmoud AM	Pharmaceuticals (Basel, Switzerland)	2024
TRPV1 alleviates APOE4-dependent microglial antigen presentation and T cell infiltration in Alzheimer's disease. Lu J, Wu K, Sha X, Lin J, Chen H, Yu Z	Translational neurodegeneration	2024
(E)-5-hydroxy-7-methoxy-3-(2-hydroxybenzyl)-4-chromanone, a Major Homoisoflavonoid, Attenuates Free Fatty Acid-Induced Hepatic Steatosis by Activating AMPK and PPARα Pathways in HepG2 Cells. Park JE, Han JS	Nutrients	2024
Disrupted Post-Transcriptional Regulation of Gene Expression as a Hallmark of Fatty Liver Progression. Takaoka S, Jaso-Vera ME, Ruan X	International journal of molecular sciences	2024
Platelet-Derived Growth Factor C Facilitates Malignant Behavior of Pancreatic Ductal Adenocarcinoma by Regulating SREBP1 Mediated Lipid Metabolism. Shi YH, Liu ZD, Ma MJ, Zhao GY, Zhu YQ, Wang JQ, Yu YY, Huang XT, Ye JY, Li FX, Wang XY, Xu QC, Yin XY	Advanced science (Weinheim, Baden-Wurttemberg, Germany)	2024
Polyoxometalates Ameliorate Metabolic Dysfunction-Associated Steatotic Liver Disease by Activating the AMPK Signaling Pathway Wang D, Wang J, Yin Z, Gong K, Zhang S, Zha Z, Duan Y	International Journal of Nanomedicine	2024
Modulation of gene expression in immune-related organs by in ovo stimulation with probiotics and prophybiotics in broiler chickens. Wishna-Kadawarage RN, Połtowicz K, Hickey RM, Siwek M	Journal of applied genetics	2024
Bile Acid Signaling in Metabolic and Inflammatory Diseases and Drug Development Li T, Chiang JY	Pharmacological Reviews	2024
Time-Restricted Feeding Attenuates Adipose Tissue Inflammation and Fibrosis in Mice Under Chronic Light Exposure Nah J, Yun N, Yoo H, Park S, Pae M	International Journal of Molecular Sciences	2024
High-fat-diet-induced hepatic insulin resistance per se attenuates murine de novo lipogenesis Goedeke L, Strober JW, Suh R, Paolella LM, Li X, Rogers JC, Petersen MC, Nasiri AR, Casals G, Kahn M, Cline GW, Samuel VT, Shulman GI, Vatner DF	iScience	2024
SREBP1 induction mediates long-term statins therapy related myocardial lipid peroxidation and lipid deposition in TIIDM mice. Huang TS, Wu T, Fu XL, Ren HL, He XD, Zheng DH, Tan J, Shen CH, Xiong SJ, Qian J, Zou Y, Wan JH, Ji YJ, Liu MY, Wu YD, Li XH, Li H, Zheng K, Yang XF, Wang H, Ren M, Cai WB	Redox biology	2024
Roles of posttranslational modifications in lipid metabolism and cancer progression Feng T, Zhang H, Zhou Y, Zhu Y, Shi S, Li K, Lin P, Chen J	Biomarker Research	2024
Cyanidin‐3‐O‐glucoside ameliorates hydrogen peroxide‐induced oxidative stress by regulating HMGCR‐mediated cholesterol anabolism in HEK‐293T cells Liu D, Zhang H, Dai Y, Sun J, Sun H, Yu Z, Kong F, Feng X	Food Science & Nutrition	2024
Replacement of fish meal with full fat Hermetia illucens modulates hepatic FXR signaling in juvenile rainbow trout (Oncorhynchus mykiss): Exploring a potential role of ecdysteroids Cocci P, Angeletti M, Mosconi G, Olivotto I, Zarantoniello M, Palermo FA	Heliyon	2024
Precise targeting of lipid metabolism in the era of immuno-oncology and the latest advances in nano-based drug delivery systems for cancer therapy Zhang H, Li Y, Huang J, Shen L, Xiong Y	Acta Pharmaceutica Sinica. B	2024
HIV-TAT dysregulates microglial lipid metabolism through SREBP2/miR-124 axis: Implication of lipid droplet accumulation microglia in NeuroHIV Cheng Y, Jung J, Guo L, Shuboni-Mulligan DD, Chen JF, Hu W, Guo ML	Brain, behavior, and immunity	2024
Targeting acetyl-CoA carboxylases for the treatment of MASLD Mateo-Marín MA, Alves-Bezerra M	Journal of Lipid Research	2024
Liver proteomics identifies a disconnect between proteins associated with de novo lipogenesis and triglyceride storage Small L, Nguyen TV, Larance M, Saunders DN, Hoy AJ, Schmitz-Peiffer C, Cooney GJ, Brandon AE	Journal of Lipid Research	2024
Glycerol Kinase Drives Hepatic de novo Lipogenesis and Triglyceride Synthesis in Nonalcoholic Fatty Liver by Activating SREBP‐1c Transcription, Upregulating DGAT1/2 Expression, and Promoting Glycerol Metabolism Ouyang S, Zhuo S, Yang M, Zhu T, Yu S, Li Y, Ying H, Le Y	Advanced Science	2024
Physiological consequences of Aldolase C deficiency during lactation Votava JA, Fan J, Parks BW	PLOS ONE	2024
Dietary Se-enrich Cardamine violifolia supplementation decreases lipid deposition and improves antioxidant status in the liver of aging laying hens Yan M, Cong X, Wang H, Qin K, Tang Y, Xu X, Wang D, Cheng S, Liu Y, Zhu H	Poultry Science	2024
Sex Hormone: A Potential Target at Treating Female Metabolic Dysfunction-Associated Steatotic Liver Disease? Duan H, Gong M, Yuan G, Wang Z	Journal of Clinical and Experimental Hepatology	2024
Assessment of SREBP Activation Using a Microsomal Vesicle Budding Assay Xia M, Edwards T, Rong S	Bio-protocol	2024
The effects of saturated and unsaturated fatty acids on MASLD: a Mendelian randomization analysis and in vivo experiment Xu F, Albadry M, Döding A, Chen X, Dirsch O, Schulze-Späte U, Dahmen U	European Journal of Nutrition	2024
Branched‐chain amino acid metabolism: Pathophysiological mechanism and therapeutic intervention in metabolic diseases Mansoori S, Ho MY, Ng KK, Cheng KK	Obesity Reviews	2024
In Silico Analysis Revealed Marco (SR-A6) and Abca1/2 as Potential Regulators of Lipid Metabolism in M1 Macrophage Hysteresis Zhang Y, Yang W, Kumagai Y, Loza M, Yang Y, Park SJ, Nakai K	International Journal of Molecular Sciences	2024
Bempedoic acid suppresses diet-induced hepatic steatosis independent of ATP-citrate lyase Liu JY, Kuna RS, Pinheiro LV, Nguyen PT, Welles JE, Drummond JM, Murali N, Sharma P, Supplee JG, Shiue M, Zhao S, Farria AT, Kumar A, Ruchhoeft ML, Demetriadou C, Kantner DS, Chatoff A, Megill E, Titchenell PM, Snyder NW, Metallo CM, Wellen KE	Cell metabolism	2024
Lipid Droplets Accumulation in the Brain of HIV Transgenic Rat: Implication in the Accelerated Aging of HIV Infected Individuals Guo ML, Cheng Y, Pineda DM, Dempsey RE, Yang L	Aging and Disease	2024
From fat to fire: The lipid–inflammasome connection Anand PK	Immunological Reviews	2024
Pharmacological Mechanisms of Bile Acids Targeting the Farnesoid X Receptor Qi Y, Ma Y, Duan G	International Journal of Molecular Sciences	2024
Cholesterol restriction primes antiviral innate immunity via SREBP1-driven noncanonical type I IFNs Nishimura T, Kouwaki T, Takashima K, Ochi A, Mtali YS, Oshiumi H	EMBO Reports	2024
Hepatic retinol dehydrogenase 11 dampens stress associated with the maintenance of cellular cholesterol levels Keating MF, Yang C, Liu Y, Gould EA, Hallam MT, Henstridge DC, Mellett NA, Meikle PJ, Watt KI, Gregorevic P, Calkin AC, Drew BG	Molecular Metabolism	2024
Ethyl Lactate Ameliorates Hepatic Steatosis and Acute‐on‐Chronic Liver Injury in Alcohol‐Associated Liver Disease by Inducing Fibroblast Growth Factor 21 Jiang Y, Wei S, Shen S, Liu Y, Su W, Ding D, Zheng Z, Yu H, Zhang T, Yang Q, Zhao J, Shen Y, Fang X, Lin L, Xiao D, Cui A, Wan Q, Zhang Y, Li Y, Zhang C	Advanced Science	2024
Towards an integrated approach for understanding glia in Amyotrophic Lateral Sclerosis Majewski S, Klein P, Boillée S, Clarke BE, Patani R	Glia	2024
Small-molecule-induced epigenetic rejuvenation promotes SREBP condensation and overcomes barriers to CNS myelin regeneration Liu X, He X, Xin DE, Zhong X, Zhao C, Li Z, Zhang L, Dourson AJ, Lee L, Mishra S, Bayat AE, Nicholson E, Seibel WL, Yan B, Mason J, Turner BJ, Gonsalvez DG, Ong W, Chew SY, Ghosh B, Yoon SO, Xin M, He Z, Tchieu J, Wegner M, Nave KA, Franklin RJ, Dutta R, Trapp BD, Hu M, Smith MA, Jankowski MP, Barton SK, Lu QR	Cell	2024
A lactate-SREBP2 signaling axis drives tolerogenic dendritic cell maturation and promotes cancer progression Plebanek MP, Xue Y, Nguyen YV, DeVito NC, Wang X, Holtzhausen A, Beasley GM, Theivanthiran B, Hanks BA	Science immunology	2024
Spirulina platensis Peptide-Loaded Nanoliposomes Alleviate Hepatic Lipid Accumulation in Male Wistar Rats by Influencing Redox Homeostasis and Lipid Metabolism via the AMPK Signaling Pathway. Karimzadeh K, Unniappan S, Zahmatkesh A	Applied biochemistry and biotechnology	2024
Differential analysis of sorting nexin 10 and sterol regulatory element-binding protein 2 expression in inflammatory bowel disease. Xie B, Zhang A, Li C, Liu Y, Deng Y, Li R, Qin H, Wu B, He T, Lan D	Immunologic research	2024
Hepatic fatty acid synthase deficiency differentially affects nonalcoholic fatty liver disease and diabetes in mouse obesity models Toshiya Matsukawa, Takashi Yagi, Tohru Uchida, Mashito Sakai, Masaru Mitsushima, Takao Naganuma, Hiroyuki Yano, Yuka Inaba, Hiroshi Inoue, Kazuki Nakao, Harumi Nakao, Atsu Aiba, Yoji Nagashima, Tetsuya Kubota, Naoto Kubota, Yoshihiko Izumida, Naoya Yahagi, Hiroyuki Unoki-Kubota, Yasushi Kaburagi, Shun-ichiro Asahara, Yoshiaki Kido, Michiko Itoh, Yoshihiro Ogawa, Shiro Minami, Yasuo Terauchi, Kazuyuki Tobe, Kohjiro Ueki, Masato Kasuga, Michihiro Matsumoto	JCI Insight	2023
Deficiency in the omega-3 lysolipid transporter Mfsd2a leads to aberrant oligodendrocyte lineage development and hypomyelination Vetrivel Sengottuvel, Monalisa Hota, Jeongah Oh, Dwight Galam, Bernice Wong, Markus Wenk, Sujoy Ghosh, Federico Torta, David Silver	Journal of Clinical Investigation	2023
The bHLH-zip transcription factor SREBP regulates triterpenoid and lipid metabolisms in the medicinal fungus Ganoderma lingzhi Liu YN, Wu FY, Tian RY, Shi YX, Xu ZQ, Liu JY, Huang J, Xue FF, Liu BY, Liu GQ	Communications biology	2023
Activation of β-Adrenoceptors Promotes Lipid Droplet Accumulation in MCF-7 Breast Cancer Cells via cAMP/PKA/EPAC Pathways Silva D, Kacprzak K, Quintas C, Gonçalves J, Fresco P	International journal of molecular sciences	2023
Dietary Methionine Level Impacts the Growth, Nutrient Metabolism, Antioxidant Capacity and Immunity of the Chinese Mitten Crab (Eriocheir sinensis) under Chronic Heat Stress Liu J, Zhang C, Wang X, Li X, Huang Q, Wang H, Miao Y, Li E, Qin J, Chen L	Antioxidants	2023
More Than an Antioxidant: Role of Dietary Astaxanthin on Lipid and Glucose Metabolism in the Liver of Rainbow Trout (Oncorhynchus mykiss) Kalinowski CT, Betancor MB, Torrecillas S, Sprague M, Larroquet L, Véron V, Panserat S, Izquierdo MS, Kaushik SJ, Fontagné-Dicharry S	Antioxidants	2023
Maternal Betaine Supplementation Mitigates Maternal High Fat Diet-Induced NAFLD in Offspring Mice through Gut Microbiota Sun L, Tan X, Liang X, Chen H, Ou Q, Wu Q, Yu X, Zhao H, Huang Q, Yi Z, Wei J, Wu F, Zhu H, Wang L	Nutrients	2023
Alteration of Lipid Metabolism in Prostate Cancer: Multifaceted Oncologic Implications Zeković M, Bumbaširević U, Živković M, Pejčić T	International journal of molecular sciences	2023
Dysregulated lipid metabolism in lymphangioleiomyomatosis pathogenesis as a paradigm of chronic lung diseases Bernardelli C, Caretti A, Lesma E	Frontiers in Medicine	2023
New approach methodologies: A quantitative in vitro to in vivo extrapolation case study with PFASs Fragki S, Louisse J, Bokkers B, Luijten M, Peijnenburg A, Rijkers D, Piersma AH, Zeilmaker MJ	Food and Chemical Toxicology	2023
The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition Ganji R, Paulo JA, Xi Y, Kline I, Zhu J, Clemen CS, Weihl CC, Purdy JG, Gygi SP, Raman M	Nature Communications	2023
Systematic elucidation of genetic mechanisms underlying cholesterol uptake Hamilton MC, Fife JD, Akinci E, Yu T, Khowpinitchai B, Cha M, Barkal S, Thi TT, Yeo GH, Ramos Barroso JP, Jake Francoeur M, Velimirovic M, Gifford DK, Lettre G, Yu H, Cassa CA, Sherwood RI		2023
Fructose Induced KHK-C Increases ER Stress and Modulates Hepatic Transcriptome to Drive Liver Disease in Diet-Induced and Genetic Models of NAFLD. Park SH, Helsley RN, Fadhul T, Willoughby JL, Noetzli L, Tu HC, Solheim MH, Fujisaka S, Pan H, Dreyfuss JM, Bons J, Rose J, King CD, Schilling B, Lusis AJ, Pan C, Gupta M, Kulkarni RN, Fitzgerald K, Kern PA, Divanovic S, Kahn CR, Softic S		2023
Rapid Multiplexed Flow Cytometric Validation of CRISPRi sgRNAs in Tissue Culture Chorba JS, Xia VQ, Smith GA, Padmanabhan A	Bio-protocol	2023
A concerted mechanism involving ACAT and SREBPs by which oxysterols deplete accessible cholesterol to restrict microbial infection Heisler DB, Johnson KA, Ma DH, Ohlson MB, Zhang L, Tran M, Corley CD, Abrams ME, McDonald JG, Schoggins JW, Alto NM, Radhakrishnan A	eLife	2023
Averrhoa carambola leaves prevent dyslipidemia and oxidative stress in a rat model of poloxamer-407-induced acute hyperlipidemia Abduh MS, Saghir SA, Al Hroob AM, Bin-Ammar A, Al-Tarawni AH, Murugaiyah V, Mahmoud AM	Frontiers in pharmacology	2023
Is microRNA-33 an Appropriate Target in the Treatment of Atherosclerosis? Sidorkiewicz M	Nutrients	2023
MeCP2 Is an Epigenetic Factor That Links DNA Methylation with Brain Metabolism Vuu YM, Roberts CT, Rastegar M	International journal of molecular sciences	2023
Immune-metabolic mechanisms of post-traumatic stress disorder and atherosclerosis Tian Y, Ullah H, Gu J, Li K	Frontiers in physiology	2023
Effects of Dietary Isoleucine Supplementation on the Production Performance, Health Status and Cecal Microbiota of Arbor Acre Broiler Chickens Liu H, Sun J, Jiang S, Jiao N, Huang L, Yuan X, Guan Q, Li Y, Yang W	Microorganisms	2023
Regulation of Liver Glucose and Lipid Metabolism by Transcriptional Factors and Coactivators Ramatchandirin B, Pearah A, He L	Life Sciences	2023
Biological functions of CRTC2 and its role in metabolism-related diseases. Zheng HY, Wang YX, Zhou K, Xie HL, Ren Z, Liu HT, Ou YS, Zhou ZX, Jiang ZS	Journal of Cell Communication and Signaling	2023
Diagnostic accuracy of circular RNA for diabetes Mellitus: a systematic review and diagnostic Meta-analysis Dehghanbanadaki H, Asili P, Haji Ghadery A, Mirahmad M, Dehnavi AZ, Parsaei A, Baradaran HR, Azami M, Jose Justo da Silva G, Parvan R, Moradi Y	BMC Medical Genomics	2023
Hepatic Energy Metabolism under the Local Control of the Thyroid Hormone System Seifert J, Chen Y, Schöning W, Mai K, Tacke F, Spranger J, Köhrle J, Wirth EK	International journal of molecular sciences	2023
Regulation of De Novo Lipid Synthesis by the Small GTPase Rac1 in the Adipogenic Differentiation of Progenitor Cells from Mouse White Adipose Tissue. Hasegawa K, Takenaka N, Yamamoto M, Sakoda Y, Aiba A, Satoh T	International journal of molecular sciences	2023
Hepatitis C virus nonstructural protein 4B induces lipogenesis via the Hippo pathway. Zou C, Tan H, Zeng J, Liu M, Zhang G, Zheng Y, Zhang Z	Archives of Virology	2023
Diet-induced loss of adipose hexokinase 2 correlates with hyperglycemia Shimobayashi M, Thomas A, Shetty S, Frei IC, Wölnerhanssen BK, Weissenberger D, Vandekeere A, Planque M, Dietz N, Ritz D, Meyer-Gerspach AC, Maier T, Hay N, Peterli R, Fendt SM, Rohner N, Hall MN	eLife	2023
Effect of propolis on mood, quality of life, and metabolic profiles in subjects with metabolic syndrome: a randomized clinical trial Sajjadi SS, Bagherniya M, Soleimani D, Siavash M, Askari G	Scientific Reports	2023
Preventing high-fat diet-induced obesity and related metabolic disorders by hydrodynamic transfer of Il-27 gene. Yang Y, Liu H, Liu D	International Journal of Obesity	2023
Key events in cancer: Dysregulation of SREBPs Li Y, Wu S, Zhao X, Hao S, Li F, Wang Y, Liu B, Zhang D, Wang Y, Zhou H	Frontiers in pharmacology	2023
Mechanism of the Regulation of Plasma Cholesterol Levels by PI(4,5)P(2). Qin Y, Medina MW	Advances in experimental medicine and biology	2023
Replacing Fish Meal with Hydrolyzed Collagen Derived from Fish By-Products Improved Muscle Quality and Glycolipid Metabolism of Triploid Crucian Carp Tong F, Bai J, Tang Z, Li C, Liu S, Wei Z	Foods	2023
Lovastatin inhibits erythroleukemia progression through KLF2-mediated suppression of MAPK/ERK signaling Gao J, Hu J, Yu F, Wang C, Sheng D, Liu W, Hu A, Yu K, Xiao X, Kuang Y, Zacksenhaus E, Gajendran B, Ben-David Y	BMC Cancer	2023
SREBP activation contributes to fatty acid accumulations in necroptosis Lu D, Parisi LR, Gokcumen O, Atilla-Gokcumen GE		2023
The lysosomal LAMTOR / Ragulator complex is essential for nutrient homeostasis in brown adipose tissue Liebscher G, Vujic N, Schreiber R, Heine M, Krebiehl C, Duta-Mare M, Lamberti G, de Smet CH, Hess MW, Eichmann TO, Hölzl S, Scheja L, Heeren J, Kratky D, Huber LA	Molecular Metabolism	2023
Artesunate targets cellular metabolism to regulate the Th17/Treg cell balance. Chen K, Tang L, Nong X	Inflammation research : official journal of the European Histamine Research Society ... [et al.]	2023
Role of Lysosomal Cholesterol in Regulating PI(4,5)P(2)-Dependent Ion Channel Function. Dickson EJ	Advances in experimental medicine and biology	2023
Lipid Metabolic Reprogramming in Embryonal Neoplasms with MYCN Amplification Talapatra J, Reddy MM	Cancers	2023
The Liver and Glycogen: In Sickness and in Health Soon GS, Torbenson M	International journal of molecular sciences	2023
Fatty acid metabolism: A new therapeutic target for cervical cancer Ping P, Li J, Lei H, Xu X	Frontiers in Oncology	2023
Highlighting In Vitro the Role of Brain-like Endothelial Cells on the Maturation and Metabolism of Brain Pericytes by SWATH Proteomics Menaceur C, Hachani J, Dib S, Duban-Deweer S, Karamanos Y, Shimizu F, Kanda T, Gosselet F, Fenart L, Saint-Pol J	Cells	2023
Non-coding and intergenic genetic variants of human arylamine N-acetyltransferase 2 (NAT2) gene are associated with differential plasma lipid and cholesterol levels and cardiometabolic disorders Hong KU, Walls KM, Hein DW	Frontiers in pharmacology	2023
A novel protein encoded by circINSIG1 reprograms cholesterol metabolism by promoting the ubiquitin-dependent degradation of INSIG1 in colorectal cancer Xiong L, Liu HS, Zhou C, Yang X, Huang L, Jie HQ, Zeng ZW, Zheng XB, Li WX, Liu ZZ, Kang L, Liang ZX	Molecular Cancer	2023
Luteolin Mitigates Diabetic Dyslipidemia in Rats by Modulating ACAT-2, PPARα, SREBP-2 Proteins, and Oxidative Stress. Shehnaz SI, Roy A, Vijayaraghavan R, Sivanesan S	Applied Biochemistry and Biotechnology	2023
Aquaporin-8 ameliorates hepatic steatosis through farnesoid X receptor in obese mice Xiang M, Qian X, Han L, Wang H, Wang J, Liu W, Gu Y, Yao S, Yang J, Zhang Y, Peng Y, Zhang Z	iScience	2023
Emerging Roles of Gut Microbial Modulation of Bile Acid Composition in the Etiology of Cardiovascular Diseases. Yntema T, Koonen DPY, Kuipers F	Nutrients	2023
Applying Lipidomics to Non-Alcoholic Fatty Liver Disease: A Clinical Perspective Huang J, Sigon G, Mullish BH, Wang D, Sharma R, Manousou P, Forlano R	Nutrients	2023
High-Fat-Diet Suppressed Ketone Body Utilization for Lipogenic Pathway in Brown Adipose Tissues. Yamasaki M, Hasegawa S, Ozaki S, Imai M, Saito D, Takahashi N	Metabolites	2023
Gymnema Sylvestre Supplementation Restores Normoglycemia, Corrects Dyslipidemia, and Transcriptionally Modulates Pancreatic and Hepatic Gene Expression in Alloxan-Induced Hyperglycemic Rats Muzaffar H, Qamar I, Bashir M, Jabeen F, Irfan S, Anwar H	Metabolites	2023
Physiological and pathological roles of lipogenesis. Jeon YG, Kim YY, Lee G, Kim JB	Nature metabolism	2023
Endothelial cell-derived stem cell factor promotes lipid accumulation through c-Kit-mediated increase of lipogenic enzymes in brown adipocytes Lee HJ, Lee J, Yang MJ, Kim YC, Hong SP, Kim JM, Hwang GS, Koh GY	Nature Communications	2023
Comparative Proteomics Analysis of Pig Muscle Exudate through Label-Free Liquid Chromatography-Mass Spectrometry. Di Luca A, Ianni A, Bennato F, Martino C, Henry M, Meleady P, Martino G		2023
Elucidation of sterol biosynthesis pathway and its co-regulation with fatty acid biosynthesis in the oleaginous marine protist Schizochytrium sp. Bi Y, Guo P, Liu L, Chen L, Zhang W	Frontiers in Bioengineering and Biotechnology	2023
Systematic elucidation of genetic mechanisms underlying cholesterol uptake Hamilton MC, Fife JD, Akinci E, Yu T, Khowpinitchai B, Cha M, Barkal S, Thi TT, Yeo GH, Ramos Barroso JP, Francoeur MJ, Velimirovic M, Gifford DK, Lettre G, Yu H, Cassa CA, Sherwood RI		2023
Glucocorticoids contribute to metabolic and liver impairments induced by lactation overnutrition in male adult rats de Souza CF, Stopa LR, Martins AB, Wunderlich AL, Lopes GM, de Fatima Silva F, Komino AC, Zaia DA, Zaia CT, Lima FB, Uchoa ET	Frontiers in physiology	2023
Dysregulation of Lipid and Glucose Metabolism in Nonalcoholic Fatty Liver Disease Bhat N, Mani A	Nutrients	2023
APOE expression and secretion are modulated by mitochondrial dysfunction. Wynne ME, Ogunbona O, Lane AR, Gokhale A, Zlatic SA, Xu C, Wen Z, Duong DM, Rayaprolu S, Ivanova A, Ortlund EA, Dammer EB, Seyfried NT, Roberts BR, Crocker A, Shanbhag V, Petris M, Senoo N, Kandasamy S, Claypool SM, Barrientos A, Wingo A, Wingo TS, Rangaraju S, Levey AI, Werner E, Faundez V	eLife	2023
Dietary n-3/n-6 polyunsaturated fatty acid ratio modulates growth performance in spotted seabass (Lateolabrax maculatus) through regulating lipid metabolism, hepatic antioxidant capacity and intestinal health. Dong Y, Wei Y, Wang L, Song K, Zhang C, Lu K, Rahimnejad S		2023
PEMT Mediates Hepatitis C Virus-Induced Steatosis, Explains Genotype-Specific Phenotypes and Supports Virus Replication. Abomughaid M, Tay ESE, Pickford R, Malladi C, Read SA, Coorssen JR, Gloss BS, George J, Douglas MW	International journal of molecular sciences	2023
Taurine alleviated hepatic steatosis in oleic acid-treated-HepG2 cells and rats fed a high-fat diet Song Q, Guo JX, Ma YX, Ou T, Zhang J, Li HZ, Mi SQ, Zhang YZ, Oda H, Chen W	Heliyon	2023
Histone H2A Lys130 acetylation epigenetically regulates androgen production in prostate cancer. Nguyen T, Sridaran D, Chouhan S, Weimholt C, Wilson A, Luo J, Li T, Koomen J, Fang B, Putluri N, Sreekumar A, Feng FY, Mahajan K, Mahajan NP	Nature Communications	2023
Delivery of low-density lipoprotein from endocytic carriers to mitochondria supports steroidogenesis. Zhou YX, Wei J, Deng G, Hu A, Sun PY, Zhao X, Song BL, Luo J	Nature Cell Biology	2023
Bile acids supplementation modulates lipid metabolism, intestinal function, and cecal microbiota in geese Li G, Wang X, Liu Y, Gong S, Yang Y, Wang C, Wang H, He D	Frontiers in microbiology	2023
α-Tocopherol-13′-Carboxychromanol Induces Cell Cycle Arrest and Cell Death by Inhibiting the SREBP1-SCD1 Axis and Causing Imbalance in Lipid Desaturation Liao S, Gollowitzer A, Börmel L, Maier C, Gottschalk L, Werz O, Wallert M, Koeberle A, Lorkowski S	International journal of molecular sciences	2023
Signaling mechanisms in renal compensatory hypertrophy revealed by multi-omics. Kikuchi H, Chou CL, Yang CR, Chen L, Jung HJ, Park E, Limbutara K, Carter B, Yang ZH, Kun JF, Remaley AT, Knepper MA	Nature Communications	2023
Macrophage inhibitory cytokine-1 aggravates diet-induced gallstone formation via increased ABCG5/ABCG8 expression. Kim MH, Lee EJ, Kim SJ, Jung YJ, Park WJ, Park I	PloS one	2023
miR-33a Expression Attenuates ABCA1-Dependent Cholesterol Efflux and Promotes Macrophage-Like Cell Transdifferentiation in Cultured Vascular Smooth Muscle Cells Esobi IC, Oladosu O, Echesabal-Chen J, Powell RR, Bruce T, Stamatikos A	Journal of Lipids	2023
Molecular Research on Genes Involved in Metabolic Diseases Lara-Hernandez F, Alvarez L, Chaves J, Garcia-Garcia AB	Biomedicines	2023
SIRT1 Activator E1231 Alleviates Nonalcoholic Fatty Liver Disease by Regulating Lipid Metabolism Han J, Li S, Wang W, Jiang X, Liu C, Lei L, Li Y, Sheng R, Zhang Y, Wu Y, Zhang J, Zhang Y, Xu Y, Si S	Current issues in molecular biology	2023
Uncoupling hepatic insulin resistance – hepatic inflammation to improve insulin sensitivity and to prevent impaired metabolism-associated fatty liver disease in type 2 diabetes Niranjan S, Phillips BE, Giannoukakis N	Frontiers in Endocrinology	2023
Modeling and therapeutic targeting of inflammation-induced hepatic insulin resistance using human iPSC-derived hepatocytes and macrophages. Groeger M, Matsuo K, Heidary Arash E, Pereira A, Le Guillou D, Pino C, Telles-Silva KA, Maher JJ, Hsiao EC, Willenbring H	Nature Communications	2023
Metabolic regulation of CTCF expression and chromatin association dictates starvation response in mice and flies. Sen D, Maniyadath B, Chowdhury S, Kaur A, Khatri S, Chakraborty A, Mehendale N, Nadagouda S, Sandra US, Kamat SS, Kolthur-Seetharam U	iScience	2023
Targeting sterol-O-acyltransferase 1 to disrupt cholesterol metabolism for cancer therapy Tu T, Zhang H, Xu H	Frontiers in Oncology	2023
A therapeutically targetable TAZ-TEAD2 pathway drives the growth of hepatocellular carcinoma via ANLN and KIF23 Saito Y, Yin D, Kubota N, Wang X, Filliol A, Remotti H, Nair A, Fazlollahi L, Hoshida Y, Tabas I, Wangensteen KJ, Schwabe RF	Gastroenterology	2023
Obesity-induced metabolic imbalance allosterically modulates CtBP2 to inhibit PPAR-alpha transcriptional activity Saito K, Sekiya M, Kainoh K, Yoshino R, Hayashi A, Han SI, Araki M, Ohno H, Takeuchi Y, Tsuyuzaki T, Yamazaki D, Wanpei C, Hada L, Watanabe S, Paramita Adi Putri PI, Murayama Y, Sugano Y, Osaki Y, Iwasaki H, Yahagi N, Suzuki H, Miyamoto T, Matsuzaka T, Shimano H	The Journal of biological chemistry	2023
Thermoneutral housing promotes hepatic steatosis in standard diet-fed C57BL/6N mice, with a less pronounced effect on NAFLD progression upon high-fat feeding Horakova O, Sistilli G, Kalendova V, Bardova K, Mitrovic M, Cajka T, Irodenko I, Janovska P, Lackner K, Kopecky J, Rossmeisl M	Frontiers in Endocrinology	2023
The effect of different boron compounds on nutrient digestibility, intestinal nutrient transporters, and liver lipid metabolism ŞAHİN E, ORHAN C, ERTEN F, ŞAHİN F, ŞAHİN N, ŞAHİN K		2023
Effects of Shenling Baizhu powder on intestinal microflora metabolites and liver mitochondrial energy metabolism in nonalcoholic fatty liver mice Yao Z, Guo J, Du B, Hong L, Zhu Y, Feng X, Hou Y, Shi A	Frontiers in microbiology	2023
Statins in Cancer Prevention and Therapy Ricco N, Kron SJ	Cancers	2023
SREBP2 regulates the endothelial response to cytokines via direct transcriptional activation of KLF6 Fowler JW, Boutagy NE, Zhang R, Horikami D, Whalen MB, Romanoski CE, Sessa WC	Journal of lipid research	2023
A HIF independent oxygen-sensitive pathway for controlling cholesterol synthesis Dickson AS, Pauzaite T, Arnaiz E, Ortmann BM, West JA, Volkmar N, Martinelli AW, Li Z, Wit N, Vitkup D, Kaser A, Lehner PJ, Nathan JA	Nature Communications	2023
Environmental Determinants of Ferroptosis in Cancer Setayeshpour Y, Lee Y, Chi JT	Cancers	2023
Fumigaclavine C ameliorates liver steatosis by attenuating hepatic de novo lipogenesis via modulation of the RhoA/ROCK signaling pathway. Yu W, Gao Y, Zhao Z, Long X, Yi Y, Ai S		2023
Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor. Nicastro R, Brohée L, Alba J, Nüchel J, Figlia G, Kipschull S, Gollwitzer P, Romero-Pozuelo J, Fernandes SA, Lamprakis A, Vanni S, Teleman AA, De Virgilio C, Demetriades C	Nature Cell Biology	2023
Metabolomic and transcriptomic profiling reveals the effect of dietary protein and lipid levels on growth performance in loach (Paramisgurnus dabryanus). Wang ZR, Li SY, Zhang YZ, Li YA, Huo HH, Yu CQ, Zhou QB	Frontiers in immunology	2023
Circulating and Exosomal microRNA-33 in Childhood Obesity Cabiati M, Guiducci L, Randazzo E, Casieri V, Federico G, Del Ry S	Biomedicines	2023
Differential Expression of Subsets of Genes Related to HDL Metabolism and Atherogenesis in the Peripheral Blood in Coronary Artery Disease. Dergunov AD, Nosova EV, Rozhkova AV, Vinogradina MA, Baserova VB, Popov MA, Limborska SA, Dergunova LV	Current issues in molecular biology	2023
Hepatic SREBP signaling requires SPRING to govern systemic lipid metabolism in mice and humans. Hendrix S, Kingma J, Ottenhoff R, Valiloo M, Svecla M, Zijlstra LF, Sachdev V, Kovac K, Levels JHM, Jongejan A, de Boer JF, Kuipers F, Rimbert A, Norata GD, Loregger A, Zelcer N	Nature Communications	2023
Chitosan Oligosaccharides Alleviate Heat-Stress-Induced Lipid Metabolism Disorders by Suppressing the Oxidative Stress and Inflammatory Response in the Liver of Broilers Lan R, Luo H, Wu F, Wang Y, Zhao Z	Antioxidants	2023
Huangqin decoction alleviates lipid metabolism disorders and insulin resistance in nonalcoholic fatty liver disease by triggering Sirt1/NF-κB pathway Yan BF, Pan LF, Quan YF, Sha Q, Zhang JZ, Zhang YF, Zhou LB, Qian XL, Gu XM, Li FT, Wang T, Liu J, Zheng X	World Journal of Gastroenterology	2023
Loss of hepatic FTCD promotes lipid accumulation and hepatocarcinogenesis by upregulating PPARγ and SREBP2 Wang S, Zhou Y, Yu R, Ling J, Li B, Yang C, Cheng Z, Qian R, Lin Z, Yu C, Zheng J, Zheng X, Jia Q, Wu W, Wu Q, Chen M, Yuan S, Dong W, Shi Y, Jansen R, Yang C, Hao Y, Yao M, Qin W, Jin H	JHEP Reports	2023
Functional significance of cholesterol metabolism in cancer: from threat to treatment. Xiao M, Xu J, Wang W, Zhang B, Liu J, Li J, Xu H, Zhao Y, Yu X, Shi S	Experimental & molecular medicine	2023
Micro-Executor of Natural Products in Metabolic Diseases. Liu J, Chen H, Li X, Song C, Wang L, Wang D	Molecules (Basel, Switzerland)	2023
FAM120A couples SREBP-dependent transcription and splicing of lipogenesis enzymes downstream of mTORC1 Cho S, Chun Y, He L, Ramirez CB, Ganesh KS, Jeong K, Song J, Cheong JG, Li Z, Choi J, Kim J, Koundouros N, Ding F, Dephoure N, Jang C, Blenis J, Lee G	Molecular Cell	2023
Assaying sterol--regulated ER--to--Golgi transport of SREBP cleavage--activating protein using immunofluorescence microscopy Ishida CT, Shao W, Espenshade PJ	Methods in molecular biology (Clifton, N.J.)	2023
Adverse outcome pathway for pregnane X receptor-induced hypercholesterolemia. Itkonen A, Hakkola J, Rysä J	Archives of Toxicology	2023
LINC01705 derived from adipocyte exosomes regulates hepatocyte lipid accumulation via an miR‐552‐3p/LXR axis Lin A, He W	Journal of Diabetes Investigation	2023
CREB-Regulated Transcriptional Coactivator 2 Proteome Landscape is Modulated by SREBF1 Lim JM, Anwar MA, Han HS, Koo SH, Kim KP	Molecular & cellular proteomics : MCP	2023
Unfolded Protein Response Signaling in Liver Disorders: A 2023 Updated Review Shreya S, Grosset CF, Jain BP	International journal of molecular sciences	2023
25-hydroxycholesterol: an integrator of antiviral ability and signaling Zhang J, Zhu Y, Wang X, Wang J	Frontiers in immunology	2023
Effects of Indonesian Shortfin Eel (Anguilla bicolor) By-Product Oil Supplementation on HOMA-IR and Lipid Profile in Obese Male Wistar Rats Megawati G, Syahruddin SS, Tjandra W, Kusumawati M, Herawati DM, Gurnida DA, Musfiroh I	Nutrients	2023
Histone Modifications in NAFLD: Mechanisms and Potential Therapy Shi Y, Qi W	International journal of molecular sciences	2023
Cholesterol-dependent homeostatic regulation of very long chain sphingolipid synthesis Kim Y, Mavodza G, Senkal CE, Burd CG	The Journal of Cell Biology	2023
Organoid Establishment of Long-Term Culture Using Primary Mouse Hepatocytes and Evaluation of Liver Function Kim HM, Kim Y, Kim Y, Kim YJ, Ko KS	Preventive Nutrition and Food Science	2023
Gallstone Disease and Its Correlation With Thyroid Disorders: A Narrative Review Ravi PC, Thugu TR, Singh J, Dasireddy RR, Kumar SA, Isaac NV, Oladimeji A, DeTrolio V, Abdalla R, Mohan V, Iqbal J	Cureus	2023
Palmitoylation-driven PHF2 ubiquitination remodels lipid metabolism through the SREBP1c axis in hepatocellular carcinoma Jeong DW, Park JW, Kim KS, Kim J, Huh J, Seo J, Kim YL, Cho JY, Lee KW, Fukuda J, Chun YS	Nature Communications	2023
Insulin-induced gene 2 protects against hepatic ischemia–reperfusion injury via metabolic remodeling Wu Y, Li C, Khan AA, Chen K, Su R, Xu S, Sun Y, Gao F, Wang K, Wang X, Lian Z, Wang S, Yu M, Hu X, Yang F, Zheng S, Qiu N, Liu Z, Xu X	Journal of Translational Medicine	2023
SIRT6’s function in controlling the metabolism of lipids and glucose in diabetic nephropathy Wang Y, Liu T, Cai Y, Liu W, Guo J	Frontiers in Endocrinology	2023
Gene profiles and mutations in the development of cataracts in the ICR rat model of hereditary cataracts Takashima M, Taniguchi K, Nagaya M, Yamamura S, Takamura Y, Inatani M, Oki M	Scientific Reports	2023
Hypercapnia increases ACE2 expression and pseudo-SARS-CoV-2 entry in bronchial epithelial cells by augmenting cellular cholesterol Chen F, Matsuda A, Budinger GR, Sporn PH, Casalino-Matsuda SM	Frontiers in immunology	2023
Gene Variants Implicated in Steatotic Liver Disease: Opportunities for Diagnostics and Therapeutics Huang G, Wallace DF, Powell EE, Rahman T, Clark PJ, Subramaniam VN	Biomedicines	2023
MicroRNA Profile, Putative Diagnostic Biomarkers and RNA-Based Therapies in the Inherited Lipid Storage Disease Niemann-Pick Type C Encarnação M, David H, Coutinho MF, Moreira L, Alves S	Biomedicines	2023
Ceramide synthase 4 overexpression exerts oncogenic properties in breast cancer Kim SJ, Seo I, Kim MH, Park JW, Kim S, Park WJ	Lipids in Health and Disease	2023
Serum proteomic profile of wild stump-tailed macaques (Macaca arctoides) infected with malaria parasites in Thailand Ruengket P, Roytrakul S, Tongthainan D, Taruyanon K, Sangkharak B, Limudomporn P, Pongsuchart M, Udom C, Fungfuang W	PloS one	2023
Puerarin Prevents Bisphenol S Induced Lipid Accumulation by Reducing Liver Lipid Synthesis and Promoting Lipid Metabolism in C57BL/6J Mice. Wu ZY, Luo L, Kan YQ, Qin ML, Li HT, He QZ, Zeng HC	Toxics	2023
Soluble LDL-receptor is induced by TNF-α and inhibits hepatocytic clearance of LDL-cholesterol. Zegeye MM, Nakka SS, Andersson JSO, Söderberg S, Ljungberg LU, Kumawat AK, Sirsjö A	Journal of Molecular Medicine	2023
Rhomboid protease RHBDL4/RHBDD1 cleaves SREBP-1c at endoplasmic reticulum monitoring and regulating fatty acids Han SI, Nakakuki M, Nakagawa Y, Wang Y, Araki M, Yamamoto Y, Tokiwa H, Takeda H, Mizunoe Y, Motomura K, Ohno H, Kainoh K, Murayama Y, Aita Y, Takeuchi Y, Osaki Y, Miyamoto T, Sekiya M, Matsuzaka T, Yahagi N, Sone H, Daitoku H, Sato R, Kawano H, Shimano H		2023
Copine7 deficiency leads to hepatic fat accumulation via mitochondrial dysfunction Hwang G, Seo H, Park JC	Heliyon	2023
Hypoxia activates SREBP2 through Golgi disassembly in bone marrow‐derived monocytes for enhanced tumor growth Nakahara R, Aki S, Sugaya M, Hirose H, Kato M, Maeda K, Sakamoto DM, Kojima Y, Nishida M, Ando R, Muramatsu M, Pan M, Tsuchida R, Matsumura Y, Yanai H, Takano H, Yao R, Sando S, Shibuya M, Sakai J, Kodama T, Kidoya H, Shimamura T, Osawa T	The EMBO Journal	2023
Carbon dioxide regulates cholesterol levels through SREBP2 Bolshette N, Ezagouri S, Dandavate V, Karavaeva I, Golik M, Wang H, Espenshade PJ, Osborne TF, Han X, Asher G	PLoS Biology	2023
Sterol regulatory element-binding protein 2 maintains glioblastoma stem cells by keeping the balance between cholesterol biosynthesis and uptake Gu D, Zhou F, You H, Gao J, Kang T, Dixit D, Wu Q, Yang K, Ci S, Shan D, Fan X, Yuan W, Zhang Q, Lu C, Li D, Zhao N, Shi Z, Gao W, Lin F, Man J, Wang Q, Qian X, Mack SC, Tao W, Agnihotri S, Zhang N, You Y, Rich JN, Zhang J, Wang X	Neuro-Oncology	2023
Cefminox sodium alleviates the high-fat high-sugar-fed mice's hepatic fatty accumulation via multiple pathways Xiao L, Liang C, Gao J, Wang Y, Guo Y, Chen K, Jia X	Heliyon	2023
Regulation and targeting of SREBP-1 in hepatocellular carcinoma. Su F, Koeberle A	Cancer metastasis reviews	2023
Semaphorin 3C promotes de novo steroidogenesis in prostate cancer cells Yenki P, Bhasin S, Liu L, Nabavi N, Cheng CW, Tam KJ, Peacock JW, Adomat HH, Tombe T, Fazli L, Ivanova L, Dusek C, Khosravi S, Guns ES, Wang Y, Buttyan R, Gleave ME, Ong CJ	Endocrine Related Cancer	2023
Feeding soy protein concentrates with low or high isoflavone decreases liver inflammation by reducing lipopolysaccharide translocation Li W, Hakkak R	Frontiers in Nutrition	2023
Differential cardiomyocyte transcriptomic remodeling during in vitro Trypanosoma cruzi infection using laboratory strains provides implications on pathogenic host responses. Candray-Medina KS, Nakagama Y, Ito M, Nakagama S, Tshibangu-Kabamba E, Takeda N, Sugiura Y, Nitahara Y, Michimuko-Nagahara Y, Kaku N, Onizuka Y, Arias CE, Mejia M, Alas K, Peña S, Maejima Y, Komuro I, Nakajima-Shimada J, Kido Y	Tropical Medicine and Health	2023
Immunity-linked genes are stimulated by a membrane stress pathway linked to Golgi function and the ARF-1 GTPase. Fanelli MJ, Welsh CM, Lui DS, Smulan LJ, Walker AK	Science Advances	2023
Effect of Gut Microbiota on Blood Cholesterol: A Review on Mechanisms Deng C, Pan J, Zhu H, Chen ZY	Foods	2023
Etiology of Lipid-laden Macrophages and in the Lung Stevenson E, Smith L, Wilkinson M, Lee S, Gow A	International Immunopharmacology	2023
Transcriptomic and lipid profiling analysis reveals a functional interplay between testosterone and growth hormone in hypothyroid liver Fernández-Pérez L, Guerra B, Recio C, Cabrera-Galván JJ, García I, De La Rosa JV, Castrillo A, Iglesias-Gato D, Díaz M	Frontiers in Endocrinology	2023
Inhibition of lipid synthesis by the HIV integrase strand transfer inhibitor elvitegravir in primary rat oligodendrocyte cultures. Monnerie H, Romer M, Roth LM, Long C, Millar JS, Jordan-Sciutto KL, Grinspan JB	Frontiers in molecular neuroscience	2023
Fructose induced KHK-C can increase ER stress independent of its effect on lipogenesis to drive liver disease in diet-induced and genetic models of NAFLD. Park SH, Helsley RN, Fadhul T, Willoughby JLS, Noetzli L, Tu HC, Solheim MH, Fujisaka S, Pan H, Dreyfuss JM, Bons J, Rose J, King CD, Schilling B, Lusis AJ, Pan C, Gupta M, Kulkarni RN, Fitzgerald K, Kern PA, Divanovic S, Kahn CR, Softic S	Metabolism: clinical and experimental	2023
LncRNAs-circRNAs as Rising Epigenetic Binary Superstars in Regulating Lipid Metabolic Reprogramming of Cancers. Liu S, Jiao B, Zhao H, Liang X, Jin F, Liu X, Hu JF		2023
Multiomics analysis identifies novel facilitators of human dopaminergic neuron differentiation. Gomez Ramos B, Ohnmacht J, de Lange N, Valceschini E, Ginolhac A, Catillon M, Ferrante D, Rakovic A, Halder R, Massart F, Arena G, Antony P, Bolognin S, Klein C, Krause R, Schulz MH, Sauter T, Krüger R, Sinkkonen L	EMBO reports	2023
Lipid Metabolism Regulators Are the Possible Determinant for Characteristics of Myopic Human Scleral Stroma Fibroblasts (HSSFs) Ohguro H, Umetsu A, Sato T, Furuhashi M, Watanabe M	International journal of molecular sciences	2023
Circadian clock and lipid metabolism disorders: a potential therapeutic strategy for cancer Liu M, Zhang Z, Chen Y, Feng T, Zhou Q, Tian X	Frontiers in Endocrinology	2023
Lipid Metabolism in Metabolic-Associated Steatotic Liver Disease (MASLD) Syed-Abdul MM	Metabolites	2023
The role of KLF2 in regulating hepatic lipogenesis and blood cholesterol homeostasis via the SCAP/SREBP pathway. Huang Y, Wang YF, Ruan XZ, Lau CW, Wang L, Huang Y	Journal of lipid research	2023
25-Hydroxycholesterol in health and diseases Nguyen C, Saint-Pol J, Dib S, Pot C, Gosselet F	Journal of lipid research	2023
Identification of the novel role of sterol regulatory element binding proteins (SREBPs) in mechanotransduction and intraocular pressure regulation. Wang T, Soundararajan A, Rabinowitz J, Jaiswal A, Osborne T, Pattabiraman PP	The FASEB Journal	2023
Isotope Labeling and Biochemical Assessment of Liver-Triacylglycerol in Patients with Different Levels of Histologically-Graded Liver Disease Syed-Abdul MM, Moore MP, Wheeler AA, Ganga RR, Diaz-Arias A, Petroski GF, Rector RS, Ibdah JA, Parks EJ	The Journal of nutrition	2023
Pharmacologic inhibition of lipogenesis for the treatment of NAFLD Esler WP, Cohen DE	Journal of Hepatology	2023
A single-nucleus transcriptomic atlas of primate liver aging uncovers the pro-senescence role of SREBP2 in hepatocytes Yang S, Liu C, Jiang M, Liu X, Geng L, Zhang Y, Sun S, Wang K, Yin J, Ma S, Wang S, Belmonte JC, Zhang W, Qu J, Liu GH	Protein & Cell	2023
Rosae multiflorae fructus regulates the lipogenesis in high-fat diet-induced NAFLD mice model. Kim K, Jang HJ, Baek S, Ahn SH		2023
Pancreatic ductal adenocarcinoma chemoresistance: From metabolism reprogramming to novel treatment. Zhang J, Wang Y, Wang L, You L, Zhang T	Chinese Medical Journal	2023
Biological Role of Fructose in the Male Reproductive System: Potential Implications for Prostate Cancer Echeverría CE, Oyarzún VI, López-Cortés A, Cancino J, Sotomayor PC, Goncalves MD, Godoy AS	The Prostate	2023
The role of vitamin E in polyunsaturated fatty acid synthesis and alleviating endoplasmic reticulum stress in sub-adult grass carp (Ctenopharyngodon idella) Yao K, Feng L, Jiang WD, Liu Y, Zhang L, Mi HF, Zhou XQ, Wu P	Animal Nutrition	2023
Gene transfer and genome editing for familial hypercholesterolemia Canepari C, Cantore A		2023
Effect of mitochondrial quantity and quality controls in white adipose tissue on healthy lifespan: Essential roles of GH/IGF-1-independent pathways in caloric restriction-mediated metabolic remodeling. Otani Y, Nozaki Y, Mizunoe Y, Kobayashi M, Higami Y	Pathology international	2023
In-depth analysis of de novo lipogenesis in non-alcoholic fatty liver disease: Mechanism and pharmacological interventions Zhu Z, Zhang X, Pan Q, Zhang L, Chai J	Liver Research	2023
Caffeic acid phenethyl ester reverses doxorubicin resistance in breast cancer cells via lipid metabolism regulation at least partly by suppressing the Akt/mTOR/SREBP1 pathway Liang L, Zhao L, Yu B, Hu H, He X, Zhang Y	The Kaohsiung Journal of Medical Sciences	2023
A compound directed against S6K1 hampers fat mass expansion and mitigates diet-induced hepatosteatosis Aina LLUCH, Sonia R VEIGA, Jèssica LATORRE, José Maria Moreno-Navarrete, Núria BONIFACI, Van Dien NGUYEN, You ZHOU, Marcus HÖRING, Gerhard LIEBISCH, Vesa M OLKKONEN, David Llobet-Navas, George THOMAS, Ruth RODRÍGUEZ-BARRUECO, José Manuel Fernández-Real, Sara C. KOZMA, Francisco J. ORTEGA	JCI Insight	2022
ZBTB18 inhibits SREBP-dependent fatty acid synthesis by counteracting CTBPs and KDM1A/LSD1 activity in glioblastoma Roberto Ferrarese, Annalisa Izzo, Geoffroy Andrieux, Simon Lagies, Johanna Paulina Bartmuss, Anie Priscilla Masilamani, Alix Wasilenko, Daniela Osti, Stefania Faletti, Rana Schulzki, Shuai Yuan, Eva Kling, Valentino Ribecco, Henrik Dieter Heiland, Stefan G. Tholen, Marco Prinz, Giuliana Pelicci, Bernd Kammerer, Melanie Boerries, Maria Carro	Life science alliance	2022
Paradoxical activation of SREBP1c and de novo lipogenesis by hepatocyte-selective ACLY depletion in obese mice. Batuhan Yenilmez, Mark Kelly, Guofang Zhang, Nicole Wetoska, Olga Ilkayeva, Kyounghee Min, Leslie Rowland, Chloe DiMarzio, Wentao He, Naideline Raymond, Lawrence Lifshitz, Meixia Pan, Xianlin Han, Jun Xie, Randall Friedline, Jason Kim, Guangping Gao, Mark Herman, Christopher Newgard, Michael Czech	Journal of Biological Chemistry	2022
Sphingolipid Metabolism and Metabolic Disease X Jiang		2022
Unveiling the Role of the Fatty Acid Binding Protein 4 in the Metabolic-Associated Fatty Liver Disease J Moreno-Vedia, J Girona, D Ibarretxe, L Masana, R Rodríguez-Calvo	Biomedicines	2022
Multi-Omics Approach Reveals Dysregulation of Protein Phosphorylation Correlated with Lipid Metabolism in Mouse Non-Alcoholic Fatty Liver S Kim, R Mohallem, J Franco, K Buhman, K Kim, U Aryal	Cells	2022
Cholesterol metabolism: from lipidomics to immunology W Griffiths, Y Wang	Journal of lipid research	2022
Ammonia stimulates SCAP/Insig dissociation and SREBP-1 activation to promote lipogenesis and tumour growth C Cheng, F Geng, Z Li, Y Zhong, H Wang, X Cheng, Y Zhao, X Mo, C Horbinski, W Duan, A Chakravarti, X Cheng, D Guo	Nature metabolism	2022
Insulin Resistance: From Mechanisms to Therapeutic Strategies S Lee, S Park, C Choi	Diabetes & Metabolism Journal	2022
LncCCAT1 interaction protein PKM2 upregulates SREBP2 phosphorylation to promote osteosarcoma tumorigenesis by enhancing the Warburg effect and lipogenesis F Pu, J Liu, D Jing, F Chen, X Huang, D Shi, W Wu, H Lin, L Zhao, Z Zhang, X Lv, B Wang, Z Zhang, Z Shao	International journal of oncology	2022
Rheb Promotes Triglyceride Secretion and Ameliorates Diet-Induced Steatosis in the Liver C Du, W Yang, Z Yu, Q Yuan, D Pang, P Tang, W Jiang, M Chen, B Xiao	Frontiers in Cell and Developmental Biology	2022
Dietary Enteromorpha polysaccharide-Zn supplementation regulates amino acid and fatty acid metabolism by improving the antioxidant activity in chicken T Wassie, X Duan, C Xie, R Wang, X Wu	Journal of Animal Science and Biotechnology	2022
LncRNA NEAT1 Potentiates SREBP2 Activity to Promote Inflammatory Macrophage Activation and Limit Hantaan Virus Propagation Y Yang, M Li, Y Ma, W Ye, Y Si, X Zheng, H Liu, L Cheng, L Zhang, H Zhang, X Zhang, Y Lei, L Shen, F Zhang, H Ma	Frontiers in microbiology	2022
ApoM regulates PFKL through the transcription factor SREBF1 to inhibit the proliferation, migration and metastasis of liver cancer cells Zhang X, Bai Y, Zhu W, Lv X, Pei W	Oncology Letters	2022
Metformin enhances LDL-cholesterol uptake by suppressing the expression of the pro-protein convertase subtilisin/kexin type 9 (PCSK9) in liver cells. Ali A, Unnikannan H, Shafarin J, Bajbouj K, Taneera J, Muhammad JS, Hasan H, Salehi A, Awadallah S, Hamad M	Endocrine	2022
Effects of Oxysterols on Immune Cells and Related Diseases. de Freitas FA, Levy D, Reichert CO, Cunha-Neto E, Kalil J, Bydlowski SP	Cells	2022
Updated Understanding of the Crosstalk Between Glucose/Insulin and Cholesterol Metabolism. Xiao X, Luo Y, Peng D	Frontiers in Cardiovascular Medicine	2022
Role of mTOR Signaling Cascade in Epidermal Morphogenesis and Skin Barrier Formation Wang J, Eming SA, Ding X	Biology	2022
Beyond Lipid-Lowering: Effects of Statins on Cardiovascular and Cerebrovascular Diseases and Cancer. Morofuji Y, Nakagawa S, Ujifuku K, Fujimoto T, Otsuka K, Niwa M, Tsutsumi K	Pharmaceuticals (Basel, Switzerland)	2022
Regression of Liver Steatosis Following Phosphatidylcholine Administration: A Review of Molecular and Metabolic Pathways Involved. Osipova D, Kokoreva K, Lazebnik L, Golovanova E, Pavlov C, Dukhanin A, Orlova S, Starostin K	Frontiers in pharmacology	2022
Qualitative and Quantitative Effects of Fatty Acids Involved in Heart Diseases. Moriyama H, Endo J, Ikura H, Kitakata H, Momoi M, Shinya Y, Ko S, Ichihara G, Hiraide T, Shirakawa K, Anzai A, Katsumata Y, Sano M	Metabolites	2022
Copy number amplification of ENSA promotes the progression of triple-negative breast cancer via cholesterol biosynthesis Chen YY, Ge JY, Zhu SY, Shao ZM, Yu KD	Nature Communications	2022
MicroRNAs: master regulators in host–parasitic protist interactions Rojas-Pirela M, Andrade-Alviárez D, Medina L, Castillo C, Liempi A, Guerrero-Muñoz J, Ortega Y, Maya JD, Rojas V, Quiñones W, Michels PA, Kemmerling U	Open Biology	2022
SREBP2 promotes the viability, proliferation, and migration and inhibits apoptosis in TGF-β1-induced airway smooth muscle cells by regulating TLR2/NF-κB/NFATc1/ABCA1 regulatory network. Wang Y, Yang H, Su X, Cao A, Chen F, Chen P, Yan F, Hu H	Bioengineered	2022
Maternal Fructose Intake Causes Developmental Reprogramming of Hepatic Mitochondrial Catalytic Activity and Lipid Metabolism in Weanling and Young Adult Offspring. Smith EVL, Dyson RM, Vanderboor CMG, Sarr O, Anderson J, Berry MJ, Regnault TRH, Peng L, Gray C	International journal of molecular sciences	2022
Bio-Waste Products of Mangifera indica L. Reduce Adipogenesis and Exert Antioxidant Effects on 3T3-L1 Cells. Pratelli G, Carlisi D, D'Anneo A, Maggio A, Emanuele S, Palumbo Piccionello A, Giuliano M, De Blasio A, Calvaruso G, Lauricella M		2022
ACAT2 Is a Novel Negative Regulator of Pig Intramuscular Preadipocytes Differentiation. Tian Y, Zhao Y, Yu W, Melak S, Niu Y, Wei W, Zhang L, Chen J	Biomolecules	2022
Targeted Suppression of Lipoprotein Receptor LSR in Astrocytes Leads to Olfactory and Memory Deficits in Mice. El Hajj A, Herzine A, Calcagno G, Désor F, Djelti F, Bombail V, Denis I, Oster T, Malaplate C, Vigier M, Kaminski S, Pauron L, Corbier C, Yen FT, Lanhers MC, Claudepierre T	International journal of molecular sciences	2022
PSRC1 May Affect Coronary Artery Disease Risk by Altering CELSR2, PSRC1, and SORT1 Gene Expression and Circulating Granulin and Apolipoprotein B Protein Levels. Chai T, Wang Z, Yang X, Qiu Z, Chen L	Frontiers in Cardiovascular Medicine	2022
Targeting CRABP-II overcomes pancreatic cancer drug resistance by reversing lipid raft cholesterol accumulation and AKT survival signaling. Yu S, Wang L, Che D, Zhang M, Li M, Naito M, Xin W, Zhou L	Journal of experimental & clinical cancer research : CR	2022
Efficacy and safety of an orally administered DGAT2 inhibitor alone or coadministered with a liver-targeted ACC inhibitor in adults with non-alcoholic steatohepatitis (NASH): rationale and design of the phase II, dose-ranging, dose-finding, randomised, placebo-controlled MIRNA (Metabolic Interventions to Resolve NASH with fibrosis) study. Amin NB, Darekar A, Anstee QM, Wong VW, Tacke F, Vourvahis M, Lee DS, Charlton M, Alkhouri N, Nakajima A, Yunis C	BMJ Open	2022
Antidiabetic Action of Mcy Protein: Studies on Gene Expression and Competitive Binding to Insulin Receptors. Marella S, Kotha P, Nabi SA, Girish BP, Badri KR, Chippada A	Applied Biochemistry and Biotechnology	2022
Computational drug repurposing against SARS-CoV-2 reveals plasma membrane cholesterol depletion as key factor of antiviral drug activity. Barsi S, Papp H, Valdeolivas A, Tóth DJ, Kuczmog A, Madai M, Hunyady L, Várnai P, Saez-Rodriguez J, Jakab F, Szalai B	PLoS computational biology	2022
L-theanine prevents progression of nonalcoholic hepatic steatosis by regulating hepatocyte lipid metabolic pathways via the CaMKKβ-AMPK signaling pathway. Liang J, Gu L, Liu X, Yan X, Bi X, Fan X, Zhou J, Lu S, Luo L, Yin Z	Nutrition & Metabolism	2022
ACTL6a coordinates axonal caliber recognition and myelination in the peripheral nerve. Park HJ, Tsai E, Huang D, Weaver M, Frick L, Alcantara A, Moran JJ, Patzig J, Melendez-Vasquez CV, Crabtree GR, Feltri ML, Svaren J, Casaccia P	iScience	2022
Induction of glutathione biosynthesis by glycine-based treatment mitigates atherosclerosis. Rom O, Liu Y, Finney AC, Ghrayeb A, Zhao Y, Shukha Y, Wang L, Rajanayake KK, Das S, Rashdan NA, Weissman N, Delgadillo L, Wen B, Garcia-Barrio MT, Aviram M, Kevil CG, Yurdagul A Jr, Pattillo CB, Zhang J, Sun D, Hayek T, Gottlieb E, Mor I, Chen YE	Redox Biology	2022
Integrated Proteomic and Metabolomic Analyses of Chicken Ovary Revealed the Crucial Role of Lipoprotein Lipase on Lipid Metabolism and Steroidogenesis During Sexual Maturity. Cui Z, Ning Z, Deng X, Du X, Amevor FK, Liu L, Kang X, Tian Y, Wang Y, Li D, Zhao X	Frontiers in physiology	2022
Hydroxycinnamic acid derivatives effect on hypercholesterolemia, comparison with ezetimibe: Permeability assays and FTIR spectroscopy on Caco-2 cell line. Ressaissi A, Serralheiro MLM		2022
The GR-gp78 Pathway is involved in Hepatic Lipid Accumulation Induced by Overexpression of 11β-HSD1 Hu M, Han T, Pan Q, Ni D, Gao F, Wang L, Ren H, Zhang X, Jiao H, Wang Y, Dai D, Man Y, Tang W, Sun Y, Li W, Li J, Li G	International journal of biological sciences	2022
Key Molecules of Fatty Acid Metabolism in Gastric Cancer Li C, Zhang L, Qiu Z, Deng W, Wang W	Biomolecules	2022
Comparative Transcriptome Analysis Reveals That Exendin-4 Improves Steatosis in HepG2 Cells by Modulating Signaling Pathways Related to Lipid Metabolism Errafii K, Khalifa O, Al-Akl NS, Arredouani A	Biomedicines	2022
A Very Rare Variant in SREBF2, a Possible Cause of Hypercholesterolemia and Increased Glycemic Levels García-García AB, Martínez-Hervás S, Vernia S, Ivorra C, Pulido I, Martín-Escudero JC, Casado M, Carretero J, Real JT, Chaves FJ	Biomedicines	2022
Oleic acid reduces steroidogenesis by changing the lipid type stored in lipid droplets of ovarian granulosa cells. Zhou X, Mo Z, Li Y, Huang L, Yu S, Ge L, Hu Y, Shi S, Zhang L, Wang L, Gao L, Yang G, Chu G	Journal of Animal Science and Biotechnology	2022
Comprehensive determination of transcription start sites derived from all RNA polymerases using ReCappable-seq Yan B, Tzertzinis G, Schildkraut I, Ettwiller L	Genome research	2022
Mechanistic/mammalian target of rapamycin and side effects of antipsychotics: insights into mechanisms and implications for therapy Zhuo C, Xu Y, Hou W, Chen J, Li Q, Liu Z, Dou G, Sun Y, Li R, Ma X, Tian H, Zhou C	Translational Psychiatry	2022
A mutation in transmembrane protein 135 impairs lipid metabolism in mouse eyecups Landowski M, Bhute VJ, Takimoto T, Grindel S, Shahi PK, Pattnaik BR, Ikeda S, Ikeda A	Scientific Reports	2022
Silencing acetyl-CoA carboxylase A and sterol regulatory element-binding protein 1 genes through RNAi reduce serum and egg cholesterol in chicken Prasad AR, Bhattacharya TK, Chatterjee RN, Divya D, Bhanja SK, Shanmugam M, Sagar NG	Scientific Reports	2022
Red yeast rice ameliorates non-alcoholic fatty liver disease through inhibiting lipid synthesis and NF-κB/NLRP3 inflammasome-mediated hepatic inflammation in mice Zou J, Yan C, Wan JB	Chinese medicine	2022
The effects of voluntary wheel running during weight-loss on biomarkers of hepatic lipid metabolism and inflammation in C57Bl/6J mice Wooten JS, Poole KE, Harris MP, Guilford BL, Schaller ML, Umbaugh D, Seija A		2022
Antioxidants in Hops: Bioavailability, Health Effects and Perspectives for New Products Zugravu CA, Bohiltea RE, Salmen T, Pogurschi E, Otelea MR	Antioxidants	2022
Exosomal miR-673-5p from fibroblasts promotes Schwann cell-mediated peripheral neuron myelination by targeting the TSC2/mTORC1/SREBP2 axis Zhao Y, Liang Y, Xu Z, Liu J, Liu X, Ma J, Sun C, Yang Y	The Journal of biological chemistry	2022
Polyene Phosphatidylcholine Ameliorates High Fat Diet-Induced Non-alcoholic Fatty Liver Disease via Remodeling Metabolism and Inflammation Lu Y, Feng T, Zhao J, Jiang P, Xu D, Zhou M, Dai M, Wu J, Sun F, Yang X, Lin Q, Pan W	Frontiers in physiology	2022
Ganoderic acid A ameliorates non-alcoholic streatohepatitis (NASH) induced by high-fat high-cholesterol diet in mice Zhu J, Ding J, Li S, Jin J	Experimental and therapeutic medicine	2022
The Molecular Mechanism of Hepatic Lipid Metabolism Disorder Caused by NaAsO2 through Regulating the ERK/PPAR Signaling Pathway Wu L, Zhang S, Zhang Q, Wei S, Wang G, Luo P	Oxidative medicine and cellular longevity	2022
A Multisensory Network Drives Nuclear Mechanoadaptation Echarri A	Biomolecules	2022
Temporal Changes in the Brain Lipidome During Neurodevelopment of Smith-Lemli-Opitz Syndrome Mice Li A, Hines KM, Ross DH, MacDonald JW, Xu L	The Analyst	2022
The constellation of cholesterol-dependent processes associated with SARS-CoV-2 infection Barrantes FJ	Progress in Lipid Research	2022
Coronavirus Infection and Cholesterol Metabolism Dai J, Wang H, Liao Y, Tan L, Sun Y, Song C, Liu W, Qiu X, Ding C	Frontiers in immunology	2022
Interaction effect between NAFLD severity and high carbohydrate diet on gut microbiome alteration and hepatic de novo lipogenesis Kang H, You HJ, Lee G, Lee SH, Yoo T, Choi M, Joo SK, Park JH, Chang MS, Lee DH, Kim W, Ko G	Gut microbes	2022
The effect of bile salt diet supplementation on genes related to fat metabolism in yellow-feathered broilers Zhang Z, Ding B, He H, Wang J, Liu X, Guo J, Li P, Madigosky SR	Veterinary World	2022
Branched-Chain Fatty Acids Alter the Expression of Genes Responsible for Lipid Synthesis and Inflammation in Human Adipose Cells Czumaj A, Śledziński T, Mika A	Nutrients	2022
Blocking cholesterol efflux mechanism is a potential target for antilymphoma therapy Yano H, Fujiwara Y, Horlad H, Pan C, Kai K, Niino D, Ohsawa K, Higashi M, Nosaka K, Okuno Y, Tamaru J, Mukasa A, Matsuoka M, Komohara Y	Cancer Science	2022
Adaptation of Oxidative Phosphorylation Machinery Compensates for Hepatic Lipotoxicity in Early Stages of MAFLD Fahlbusch P, Nikolic A, Hartwig S, Jacob S, Kettel U, Köllmer C, Al-Hasani H, Lehr S, Müller-Wieland D, Knebel B, Kotzka J	International journal of molecular sciences	2022
Trends in insulin resistance: insights into mechanisms and therapeutic strategy Li M, Chi X, Wang Y, Setrerrahmane S, Xie W, Xu H	Signal Transduction and Targeted Therapy	2022
Lipid metabolism and m6A RNA methylation are altered in lambs supplemented rumen-protected methionine and lysine in a low-protein diet Gebeyew K, Yang C, Mi H, Cheng Y, Zhang T, Hu F, Yan Q, He Z, Tang S, Tan Z	Journal of Animal Science and Biotechnology	2022
Immunolipidomics Reveals a Globoside Network During the Resolution of Pro-Inflammatory Response in Human Macrophages Muralidharan S, Torta F, Lin MK, Olona A, Bagnati M, Moreno-Moral A, Ko JH, Ji S, Burla B, Wenk MR, Rodrigues HG, Petretto E, Behmoaras J	Frontiers in immunology	2022
Estrogen Mediates an Atherosclerotic-Protective Action via Estrogen Receptor Alpha/SREBP-1 Signaling Xie F, Li X, Xu Y, Cheng D, Xia X, Lv X, Yuan G, Peng C	Frontiers in Cardiovascular Medicine	2022
HDL‐mediated reduction of cholesterol content inhibits the proliferation of prostate cancer cells induced by LDL: Role of ABCA1 and proteasome inhibition Ossoli A, Giorgio E, Cetti F, Ruscica M, Rabacchi C, Tarugi P, Parini P, Pedrelli M, Gomaraschi M	BioFactors (Oxford, England)	2022
Sinapic acid prevents adipogenesis by regulating transcription factors and exerts an anti-ROS effect by modifying the intracellular anti-oxidant system in 3T3-L1 adipocytes John CM, Arockiasamy S	Iranian Journal of Basic Medical Sciences	2022
Statins and prostate cancer-hype or hope? The biological perspective. Longo J, Freedland SJ, Penn LZ, Hamilton RJ	Prostate Cancer and Prostatic Diseases	2022
Regulatory Effects of Statins on SIRT1 and Other Sirtuins in Cardiovascular Diseases Khayatan D, Razavi SM, Arab ZN, Khanahmadi M, Momtaz S, Butler AE, Montecucco F, Markina YV, Abdolghaffari AH, Sahebkar A	Life Sciences	2022
BCL2‐associated athanogene 6 exon24 contributes to testosterone synthesis and male fertility in mammals Song H, Chen D, Bai R, Feng Y, Wu S, Wang T, Xia X, Li J, Miao Y, Zuo B, Li F	Cell Proliferation	2022
Mitigation of MAFLD in High Fat-High Sucrose-Fructose Fed Mice by a Combination of Genistein Consumption and Exercise Training St Aubin CR, Fisher AL, Hernandez JA, Broderick TL, Al-Nakkash L	Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy	2022
Targeting SREBP-1-Mediated Lipogenesis as Potential Strategies for Cancer Zhao Q, Lin X, Wang G	Frontiers in Oncology	2022
Progress in Research on the Alleviation of Glucose Metabolism Disorders in Type 2 Diabetes Using Cyclocarya paliurus Wang X, Tang L, Ping W, Su Q, Ouyang S, Su J	Nutrients	2022
Effects of hawthorn seed oil on plasma cholesterol and gut microbiota Kwek E, Yan C, Ding H, Hao W, He Z, Liu J, Ma KY, Zhu H, Chen ZY	Nutrition & Metabolism	2022
Cancer cells depend on environmental lipids for proliferation when electron acceptors are limited. Li Z, Ji BW, Dixit PD, Tchourine K, Lien EC, Hosios AM, Abbott KL, Rutter JC, Westermark AM, Gorodetsky EF, Sullivan LB, Vander Heiden MG, Vitkup D	Nature metabolism	2022
Metabolic mechanisms for and treatment of NAFLD or NASH occurring after liver transplantation. Lonardo A, Mantovani A, Petta S, Carraro A, Byrne CD, Targher G	Nature reviews. Endocrinology	2022
Long non-coding RNAs: a valuable biomarker for metabolic syndrome. Rashidmayvan M, Sahebi R, Ghayour-Mobarhan M	Molecular genetics and genomics : MGG	2022
Chitosan reduces inflammation and protects against oxidative stress in a hyperlipidemic rat model: relevance to nonalcoholic fatty liver disease. Kumar R, Arya JK, Rizvi SI	Molecular Biology Reports	2022
Cancer therapy's impact on lipid metabolism: Mechanisms and future avenues. Bhatnagar R, Dixit NM, Yang EH, Sallam T	Frontiers in Cardiovascular Medicine	2022
Inflammatory stress signaling via NF-kB alters accessible cholesterol to upregulate SREBP2 transcriptional activity in endothelial cells. Fowler JWM, Zhang R, Tao B, Boutagy NE, Sessa WC	eLife	2022
Lipid Metabolism in Glioblastoma: From De Novo Synthesis to Storage Kou Y, Geng F, Guo D	Biomedicines	2022
Impact of Non-Pharmacological Interventions on the Mechanisms of Atherosclerosis Matei D, Buculei I, Luca C, Corciova CP, Andritoi D, Fuior R, Iordan DA, Onu I	International journal of molecular sciences	2022
Postnatal eye size in mice is controlled by SREBP2-mediated transcriptional repression of Lrp2 and Bmp2. Mai S, Zhu X, Wan EYC, Wu S, Yonathan JN, Wang J, Li Y, Ma JYW, Zuo B, Tse DY, Lo PC, Wang X, Chan KM, Wu DM, Xiong W	Development (Cambridge, England)	2022
NLRP3 Inflammasome Priming and Activation Are Regulated by a Phosphatidylinositol-Dependent Mechanism Hamilton C, Olona A, Leishman S, MacDonald-Ramsahai K, Cockcroft S, Larrouy-Maumus G, Anand PK	ImmunoHorizons	2022
Investigation of Transcript Variant 6 of TPD52L2 as a Prognostic and Predictive Biomarker in Basal-Like MDA-MB-231 and MDA-MB-453 Cell Lines for Breast Cancer Zhang X, O'Brien D, Zhang X	Oxidative medicine and cellular longevity	2022
Enteromorpha polysaccharide and yeast glycoprotein mixture improves growth, antioxidant activity, serum lipid profile and regulates lipid metabolism in broiler chickens Wassie T, Cheng B, Zhou T, Gao L, Lu Z, Wang J, Mulu B, Taye M, Wu X	Poultry science	2022
MYCN and Metabolic Reprogramming in Neuroblastoma. Bansal M, Gupta A, Ding HF	Cancers	2022
miR-539-5p regulates Srebf1 transcription in the skeletal muscle of diabetic mice by targeting DNA methyltransferase 3b. Kesharwani D, Kumar A, Rizvi A, Datta M		2022
GCAF(TMEM251) regulates lysosome biogenesis by activating the mannose-6-phosphate pathway. Zhang W, Yang X, Li Y, Yu L, Zhang B, Zhang J, Cho WJ, Venkatarangan V, Chen L, Burugula BB, Bui S, Wang Y, Duan C, Kitzman JO, Li M	Nature Communications	2022
SREBP2-dependent lipid gene transcription enhances the infection of human dendritic cells by Zika virus. Branche E, Wang YT, Viramontes KM, Valls Cuevas JM, Xie J, Ana-Sosa-Batiz F, Shafee N, Duttke SH, McMillan RE, Clark AE, Nguyen MN, Garretson AF, Crames JJ, Spann NJ, Zhu Z, Rich JN, Spector DH, Benner C, Shresta S, Carlin AF	Nature Communications	2022
Super-enhancer-associated INSM2 regulates lipid metabolism by modulating mTOR signaling pathway in neuroblastoma. Cao H, Zhuo R, Zhang Z, Wang J, Tao Y, Yang R, Guo X, Chen Y, Jia S, Yao Y, Yang P, Yu J, Jiao W, Li X, Fang F, Xie Y, Li G, Wu D, Wang H, Feng C, Xu Y, Li Z, Pan J, Wang J	Cell & Bioscience	2022
Targets of statins intervention in LDL-C metabolism: Gut microbiota Sun C, Wang Z, Hu L, Zhang X, Chen J, Yu Z, Liu L, Wu M	Frontiers in Cardiovascular Medicine	2022
Peroxisome Proliferator-Activated Receptor α Has a Protective Effect on Fatty Liver Caused by Excessive Sucrose Intake Yamazaki T, Ihato M	Biomedicines	2022
Lung Adenocarcinoma Cell Sensitivity to Chemotherapies: A Spotlight on Lipid Droplets and SREBF1 Gene Gründing AR, Schneider MA, Richtmann S, Kriegsmann M, Winter H, Martinez-Delgado B, Varona S, Liu B, DeLuca DS, Held J, Wrenger S, Muley T, Meister M, Welte T, Janciauskiene S	Cancers	2022
Bioinformatics Analysis and Structure of Gastric Cancer Prognosis Model Based on Lipid Metabolism and Immune Microenvironment Chen Y, Yuan H, Yu Q, Pang J, Sheng M, Tang W	Genes & development	2022
Use of Ferulic Acid in the Management of Diabetes Mellitus and Its Complications Li X, Wu J, Xu F, Chu C, Li X, Shi X, Zheng W, Wang Z, Jia Y, Xiao W	Molecules (Basel, Switzerland)	2022
Long non-coding RNA NEAT1 mediated RPRD1B stability facilitates fatty acid metabolism and lymph node metastasis via c-Jun/c-Fos/SREBP1 axis in gastric cancer. Jia Y, Yan Q, Zheng Y, Li L, Zhang B, Chang Z, Wang Z, Tang H, Qin Y, Guan XY	Journal of experimental & clinical cancer research : CR	2022
Loss of the Fbw7 tumor suppressor rewires cholesterol metabolism in cancer cells leading to activation of the PI3K-AKT signalling axis Bengoechea-Alonso MT, Aldaalis A, Ericsson J	Frontiers in Oncology	2022
Pathogenic gain-of-function mutations in the prodomain and C-terminal domain of PCSK9 inhibit LDL binding Sarkar SK, Matyas A, Asikhia I, Hu Z, Golder M, Beehler K, Kosenko T, Lagace TA	Frontiers in physiology	2022
Mechanistic Target of Rapamycin Complex 1: From a Nutrient Sensor to a Key Regulator of Metabolism and Health Wang G, Chen L, Qin S, Zhang T, Yao J, Yi Y, Deng L	Advances in Nutrition	2022
Lysosomal acid lipase deficiency: A rare inherited dyslipidemia but potential ubiquitous factor in the development of atherosclerosis and fatty liver disease Besler KJ, Blanchard V, Francis GA	Frontiers in Genetics	2022
N-3 polyunsaturated fatty acids may affect the course of COVID-19 Lampova B, Doskocil I, Kourimska L, Kopec A	Frontiers in immunology	2022
Seed- and leaf-based expression of FGF21-transferrin fusion proteins for oral delivery and treatment of non-alcoholic steatohepatitis Hou HW, Bishop CA, Huckauf J, Broer I, Klaus S, Nausch H, Buyel JF	Frontiers in Plant Science	2022
Synthesis, function, and regulation of sterol and nonsterol isoprenoids. Faulkner R, Jo Y	Frontiers in Molecular Biosciences	2022
Important Hormones Regulating Lipid Metabolism. Zhang D, Wei Y, Huang Q, Chen Y, Zeng K, Yang W, Chen J, Chen J	Molecules (Basel, Switzerland)	2022
Metabolic features of innate lymphoid cells. Yu H, Jacquelot N, Belz GT	Journal of Experimental Medicine	2022
Acetyl Co-A Carboxylase Inhibition Halts Hyperglycemia Induced Upregulation of De Novo Lipogenesis in Podocytes and Proximal Tubular Cells. Kayampilly P, Roeser N, Rajendiran TM, Pennathur S, Afshinnia F	Metabolites	2022
Metabolic injury of hepatocytes promotes progression of NAFLD and AALD Carvalho-Gontijo R, Han C, Zhang L, Zhang V, Hosseini M, Mekeel K, Schnabl B, Loomba R, Karin M, Brenner DA, Kisseleva T	Seminars in liver disease	2022
A Novel, Orally Bioavailable, Small-Molecule Inhibitor of PCSK9 With Significant Cholesterol-Lowering Properties In Vivo. Suchowerska AK, Stokman G, Palmer JT, Coghlan PA, Pieterman EJ, Keijzer N, Lambert G, Chemello K, Jaafar AK, Parmar J, Yan L, Tong Y, Mu L, Princen HMG, Bonnar J, Evison BJ	Journal of lipid research	2022
Sphingosine 1-phosphate mediates adiponectin receptor signaling essential for lipid homeostasis and embryogenesis. Ruiz M, Devkota R, Panagaki D, Bergh PO, Kaper D, Henricsson M, Nik A, Petkevicius K, Höög JL, Bohlooly-Y M, Carlsson P, Borén J, Pilon M	Nature Communications	2022
O-GlycNacylation Remission Retards the Progression of Non-Alcoholic Fatty Liver Disease Zhou Y, Li Z, Xu M, Zhang D, Ling J, Yu P, Shen Y	Cells	2022
Orsay Virus Infection of Caenorhabditis elegans Is Modulated by Zinc and Dependent on Lipids. Casorla-Perez LA, Guennoun R, Cubillas C, Peng B, Kornfeld K, Wang D	Journal of virology	2022
Transcriptome Analysis Reveals That SREBP Modulates a Large Repertoire of Genes Involved in Key Cellular Functions in Penaeus vannamei, although the Majority of the Dysregulated Genes Are Unannotated. Zheng X, Huang Z, Liu Z, Zheng Z, Zhang Y, Aweya JJ	Genes & development	2022
Allicin and Capsaicin Ameliorated Hypercholesterolemia by Upregulating LDLR and Downregulating PCSK9 Expression in HepG2 Cells Nawaka N, Wanmasae S, Makarasen A, Dechtrirat D, Techasakul S, Jeenduang N	International journal of molecular sciences	2022
Lactobacillus reuteri MJM60668 Prevent Progression of Non-Alcoholic Fatty Liver Disease through Anti-Adipogenesis and Anti-Inflammatory Pathway Werlinger P, Nguyen HT, Gu M, Cho JH, Cheng J, Suh JW	Microorganisms	2022
Discrete Correlation Summation Clustering Reveals Differential Regulation of Liver Metabolism by Thrombospondin-1 in Low-Fat and High-Fat Diet-Fed Mice Bronson SM, Westwood B, Cook KL, Emenaker NJ, Chappell MC, Roberts DD, Soto-Pantoja DR	Metabolites	2022
Mouse promyelocytic leukemia zinc finger protein (PLZF) regulates hepatic lipid and glucose homeostasis dependent on SIRT1 Hu H, Sun N, Du H, He Y, Pan K, Liu X, Lu X, Wei J, Liao M, Duan C	Frontiers in pharmacology	2022
Transcriptional Regulation of Human Arylamine N-Acetyltransferase 2 Gene by Glucose and Insulin in Liver Cancer Cell Lines Hong KU, Salazar-González RA, Walls KM, Hein DW	Toxicological Sciences	2022
A novel small compound TOIDC suppresses lipogenesis via SREBP1-dependent signaling to curb MAFLD Shao Y, Yao Z, Zhou J, Yu M, Chen S, Yuan Y, Han L, Jiang L, Liu J	Nutrition & Metabolism	2022
Diosgenin Ameliorated Type II Diabetes-Associated Nonalcoholic Fatty Liver Disease through Inhibiting De Novo Lipogenesis and Improving Fatty Acid Oxidation and Mitochondrial Function in Rats Zhong Y, Li Z, Jin R, Yao Y, He S, Lei M, Wang X, Shi C, Gao L, Peng X	Nutrients	2022
The prognosis of lipid reprogramming with the HMG-CoA reductase inhibitor, rosuvastatin, in castrated Egyptian prostate cancer patients: Randomized trial. Karkeet RM, Zekri AN, Sayed-Ahmed MM, Sherif GM, Salem SE, Abdelbary A, Fouad MA, Saad SY	PloS one	2022
NSCLC Cells Resistance to PI3K/mTOR Inhibitors Is Mediated by Delta-6 Fatty Acid Desaturase (FADS2). Colombo M, Passarelli F, Corsetto PA, Rizzo AM, Marabese M, De Simone G, Pastorelli R, Broggini M, Brunelli L, Caiola E	Cells	2022
The Aurora Kinase Inhibitor TAK901 Inhibits Glioblastoma Growth by Blocking SREBP1-Mediated Lipid Metabolism. Zhan X, Qiu R, He Y, Zhao Z, Huang M, Liu Q, Zhi F, Long W	Cancers	2022
The Non Catalytic Protein ERG28 has a Functional Role in Cholesterol Synthesis and is Coregulated Transcriptionally. Capell-Hattam IM, Fenton NM, Coates HW, Sharpe LJ, Brown AJ	Journal of lipid research	2022
NAP1L5 targeting combined with MYH9 Inhibit HCC progression through PI3K/AKT/mTOR signaling pathway. Zhao R, Ge Y, Gong Y, Li B, Xiao B, Zuo S	Aging	2022
Aqueous extract of Artemisia capillaris improves non-alcoholic fatty liver and obesity in mice induced by high-fat diet Liang M, Huo M, Guo Y, Zhang Y, Xiao X, Xv J, Fang L, Li T, Wang H, Dong S, Jiang X, Yu W	Frontiers in pharmacology	2022
Interferon-inducible SAMHD1 restricts viral replication through downregulation of lipid synthesis An N, Ge Q, Shao H, Li Q, Guo F, Liang C, Li X, Yi D, Yang L, Cen S	Frontiers in immunology	2022
Insulin resistance phenotype is associated with vascular risk phenotype at the end of the second decade of life: a population-based study Barbosa JM, da Silva AA, Batista RF, Salgado BJ, Nascimento JX, Simões VM, Ribeiro MJ, Barbieri MA, Ferraro AA, Ribeiro CC	Cardiovascular Diabetology	2022
Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice. Paterson HAB, Yu S, Artigas N, Prado MA, Haberman N, Wang YF, Jobbins AM, Pahita E, Mokochinski J, Hall Z, Guerin M, Paulo JA, Ng SS, Villarroya F, Rashid ST, Le Goff W, Lenhard B, Cebola I, Finley D, Gygi SP, Sibley CR, Vernia S	Nature metabolism	2022
Retinoic Acid Increases Cellular Cholesterol in Leishmania donovani-Infected Macrophages in an mTOR-Independent Manner. Prakash S, Rai AK	Microbiology spectrum	2022
Lactobacillus salivarius SNK-6 Regulates Liver Lipid Metabolism Partly via the miR-130a-5p/MBOAT2 Pathway in a NAFLD Model of Laying Hens Zhu L, Liao R, Huang J, Xiao C, Yang Y, Wang H, He D, Yan H, Yang C	Cells	2022
mTORC1 regulates a lysosome-dependent adaptive shift in intracellular lipid species Hosios AM, Wilkinson M, McNamara MC, Kalafut KC, Torrence ME, Asara JM, Manning BD	Nature metabolism	2022
Myelin lipid metabolism and its role in myelination and myelin maintenance Barnes-Vélez JA, Aksoy Yasar FB, Hu J		2022
Circadian regulation of gene expression and metabolism in the liver Guan D, Lazar MA	Seminars in liver disease	2022
Hydroxylation site–specific and production-dependent effects of endogenous oxysterols on cholesterol homeostasis: Implications for SREBP-2 and LXR Saito H, Tachiura W, Nishimura M, Shimizu M, Sato R, Yamauchi Y	The Journal of biological chemistry	2022
Inhibition of nonalcoholic fatty liver disease in mice by selective inhibition of mTORC1 Gosis BS, Wada S, Thorsheim C, Li K, Jung S, Rhoades JH, Yang Y, Brandimarto J, Li L, Uehara K, Jang C, Lanza M, Sanford NB, Bornstein MR, Jeong S, Titchenell PM, Biddinger SB, Arany Z	Science (New York, N.Y.)	2022
Overview of Cancer Metabolism and Signaling Transduction Chae HS, Hong ST	International journal of molecular sciences	2022
Current Understanding on the Role of Lipids in Macrophages and Associated Diseases Florance I, Ramasubbu S	International journal of molecular sciences	2022
Rewiring Lipid Metabolism by Targeting PCSK9 and HMGCR to Treat Liver Cancer. Alannan M, Trézéguet V, Amoêdo ND, Rossignol R, Mahfouf W, Rezvani HR, Dittrich-Domergue F, Moreau P, Lacomme S, Gontier E, Grosset CF, Badran B, Fayyad-Kazan H, Merched AJ	Cancers	2022
Podocalyxin-Like Protein 1 Regulates Pluripotency through the Cholesterol Biosynthesis Pathway. Chen WJ, Huang WK, Pather SR, Chang WF, Sung LY, Wu HC, Liao MY, Lee CC, Wu HH, Wu CY, Liao KS, Lin CY, Yang SC, Lin H, Lai PL, Ng CH, Hu CM, Chen IC, Chuang CH, Lai CY, Lin PY, Lee YC, Schuyler SC, Schambach A, Lu FL, Lu J		2022
Adipose lipolysis is important for ethanol to induce fatty liver in the NIAAA murine model of chronic and binge ethanol feeding Mathur M, Yeh YT, Arya RK, Jiang L, Pornour M, Chen W, Ma Y, Gao B, He L, Ying Z, Xue B, Shi H, Choi Y, Yu L	Hepatology	2022
Effects of maternal cigarette smoke exposure on the progression of nonalcoholic steatohepatitis in offspring mice Yang D, Kim JW, Jeong H, Kim MS, Lim CW, Lee K, Kim B	Toxicological Research	2022
Pluchea indica Leaf Extract Alleviates Dyslipidemia and Hepatic Steatosis by Modifying the Expression of Lipid Metabolism-Related Genes in Rats Fed a High Fat-High Fructose Diet Singdam P, Naowaboot J, Senggunprai L, Boonloh K, Pannangpetch P	Preventive Nutrition and Food Science	2022
G9a Modulates Lipid Metabolism in CD4 T Cells to Regulate Intestinal Inflammation Ramos GP, Bamidele AO, Klatt EE, Sagstetter MR, Kurdi AT, Hamdan FH, Kosinsky RL, Gaballa JM, Nair A, Sun Z, Dasari S, Lanza IR, Rozeveld CN, Schott MB, Urrutia G, Westphal MS, Clarkson BD, Howe CL, Marietta EV, Luckey DH, Murray JA, Gonzalez M, Braga Neto MB, Gibbons HR, Smyrk TC, Johnsen S, Lomberk G, Faubion WA	Gastroenterology	2022
Macrophage derived 25-hydroxycholesterol promotes vascular inflammation, atherogenesis and lesion remodeling Canfrán-Duque A, Rotllan N, Zhang X, Andrés-Blasco I, Thompson BM, Sun J, Price NL, Fernández-Fuertes M, Fowler JW, Gómez-Coronado D, Sessa WC, Giannarelli C, Schneider RJ, Tellides G, McDonald JG, Fernández-Hernando C, Suárez Y	Circulation	2022
Cholesterol in Brain Development and Perinatal Brain Injury: More than a Building Block Lu F, Ferriero DM, Jiang X	Current neuropharmacology	2022
Crosstalk between fatty acid metabolism and tumour-associated macrophages in cancer progression Zaidi NE, Shazali NA, Leow TC, Osman MA, Ibrahim K, Rahman NM	BioMedicine	2022
The organotin triphenyltin disrupts cholesterol signaling in mammalian ovarian steroidogenic cells through a combination of LXR and RXR modulation Pu Y, Ticiani E, Pearl S, Martin D, Veiga-Lopez A	Toxicology and Applied Pharmacology	2022
Dendritic cell marker Clec4a4 deficiency limits atherosclerosis progression Bellini R, Moregola A, Nour J, Rombouts Y, Neyrolles O, Uboldi P, Bonacina F, Norata GD		2022
Reprogramming of Hepatic Metabolism and Liver Microenvironment in Nonalcoholic Steatohepatitis Rui L, Lin JD	Annual Review of Nutrition	2022
Alzheimer's-Associated Upregulation of Mitochondria-Associated ER Membranes After Traumatic Brain Injury. Agrawal RR, Larrea D, Xu Y, Shi L, Zirpoli H, Cummins LG, Emmanuele V, Song D, Yun TD, Macaluso FP, Min W, Kernie SG, Deckelbaum RJ, Area-Gomez E	Cellular and Molecular Neurobiology	2022
Transcriptional profiling of drug-induced liver injury biomarkers: association of hepatic Srebf1/Pparα signaling and crosstalk of thrombin, alcohol dehydrogenase, MDR and DNA damage regulators. Ghanim BY, Ahmad M, Abdallah Q, Khaleel A, Qinna NA	Molecular and Cellular Biochemistry	2022
Circulating mir-200c and mir-33a may be used as biomarkers for predicting high fructose corn syrup-induced fatty liver and vitamin D supplementation-related liver changes TANOĞLU A, ÇAĞILTAY E, TANOĞLU EG, GÖKHAN A, ŞİRİN C, ÇAVUŞOĞLU T, YEŞİLBAŞ S		2022
SREBP signaling is essential for effective B cell responses Luo W, Adamska JZ, Li C, Verma R, Liu Q, Hagan T, Wimmers F, Gupta S, Feng Y, Jiang W, Zhou J, Valore E, Wang Y, Trisal M, Subramaniam S, Osborne TF, Pulendran B	Nature Immunology	2022
Antagonism of miR-148a attenuates atherosclerosis progression in APOB(TG)Apobec(-/-)Ldlr(+/-) mice: A brief report. Rotllan N, Zhang X, Canfrán-Duque A, Goedeke L, Griñán R, Ramírez CM, Suárez Y, Fernández-Hernando C	Biomedicine & Pharmacotherapy	2022
Deregulated transcription factors in cancer cell metabolisms and reprogramming Kant R, Manne RK, Anas M, Penugurti V, Chen T, Pan BS, Hsu CC, Lin HK	Seminars in Cancer Biology	2022
Heterogeneous population of macrophages in the development of non-alcoholic fatty liver disease Cho YE, Kwon YS, Hwang S	Liver Research	2022
Hypomorphic ASGR1 Modulates Lipid Homeostasis via INSIG1 Mediated SREBPs Signaling Suppression Yingying Xu, Jiawang Tao, Xiaorui Yu, Yuhang Wu, Yan Chen, Kai You, Jiaye Zhang, Anteneh Getachew, Tingcai Pan, Yuanqi Zhuang, Fang Yuan, Fan Yang, Xianhua Lin, Yin-xiong Li	JCI Insight	2021
Role of endothelial cells in pulmonary fibrosis via SREBP2 activation MARCY MARTIN, Jiao Zhang, Yifei Miao, Ming He, Jian Kang, Hsi-Yuan Huang, Chih-Hung Chou, Tse-Shun Huang, Hsiao-Chin Hong, Shu-Han Su, Simon S. Wong, Rebecca L Harper, Lingli Wang, Rakesh Bhattacharjee, Hsien-Da Huang, Zhen Bouman Chen, Atul Malhotra, M.D., Marlene Rabinovitch, James S. Hagood, John Shyy	JCI Insight	2021
Genome-scale CRISPR screening for modifiers of cellular LDL uptake BT Emmer, EJ Sherman, PJ Lascuna, SE Graham, CJ Willer, D Ginsburg, P Tontonoz	PLoS genetics	2021
Aberrant lung lipids cause respiratory impairment in a Mecp2 -deficient mouse model of Rett syndrome N Vashi, C Ackerley, M Post, MJ Justice	Human Molecular Genetics	2021
Pyruvate carboxylase promotes thyroid cancer aggressiveness through fatty acid synthesis C Liu, X Zhou, Y Pan, Y Liu, Y Zhang	BMC Cancer	2021
Druggability of lipid metabolism modulation against renal fibrosis Y Chen, X Chen, S Zhang	Acta Pharmacologica Sinica	2021
FXR activation protects against NAFLD via bile-acid-dependent reductions in lipid absorption BL Clifford, LR Sedgeman, KJ Williams, P Morand, A Cheng, KE Jarrett, AP Chan, MC Brearley-Sholto, A Wahlström, JW Ashby, W Barshop, J Wohlschlegel, AC Calkin, Y Liu, A Thorell, PJ Meikle, BG Drew, JJ Mack, HU Marschall, EJ Tarling, PA Edwards, TQ de Aguiar Vallim	Cell Metabolism	2021
Cross-species data integration to prioritize causal genes in lipid metabolism JA Votava, BW Parks	Current Opinion in Lipidology	2021
Regulation of Osteoclast Differentiation and Activity by Lipid Metabolism H Kim, B Oh, KH Park-Min	Cells	2021
β2-spectrin (SPTBN1) as a therapeutic target for diet-induced liver disease and preventing cancer development S Rao, X Yang, K Ohshiro, S Zaidi, Z Wang, K Shetty, X Xiang, I Hassan, T Mohammad, P Latham, B Nguyen, L Wong, H Yu, Y Al-Abed, B Mishra, M Vacca, G Guenigault, M Allison, A Vidal-Puig, J Benhammou, M Alvarez, P Pajukanta, J Pisegna, L Mishra	Science Translational Medicine	2021
Contributions of microRNAs to Peripheral Insulin Sensitivity K Kim, S Hartig	Endocrinology	2021
miR‐33 in cardiometabolic diseases: lessons learned from novel animal models and approaches NL Price, L Goedeke, Y Suárez, C FernándezHernando	EMBO Molecular Medicine	2021
MicroRNA regulation of cholesterol metabolism K Citrin, C FernándezHernando, Y Suárez	Annals of the New York Academy of Sciences	2021
Metabolic drivers of non-alcoholic fatty liver disease KK Bence, MJ Birnbaum	Molecular Metabolism	2021
Role of Insulin Resistance in MAFLD Y Sakurai, N Kubota, T Yamauchi, T Kadowaki	International journal of molecular sciences	2021
INPP4B protects from metabolic syndrome and associated disorders M Zhang, Y Ceyhan, EM Kaftanovskaya, JL Vasquez, J Vacher, FK Knop, L Nathanson, AI Agoulnik, MM Ittmann, IU Agoulnik		2021
Seasonal Consumption of Cherries from Different Origins Affects Metabolic Markers and Gene Expression of Lipogenic Enzymes in Rat Liver: A Preliminary Study MJ de Azua, Á Cruz-Carrión, B Muguerza, A Arola-Arnal, M Suarez	Nutrients	2021
Metabolic Control of Sensory Neuron Survival by the p75 Neurotrophin Receptor in Schwann Cells RM Follis, C Tep, TC Genaro-Mattos, ML Kim, JC Ryu, VE Morrison, JR Chan, N Porter, BD Carter, SO Yoon	The Journal of neuroscience : the official journal of the Society for Neuroscience	2021
The Interactions of Insulin and Vitamin A Signaling Systems for the Regulation of Hepatic Glucose and Lipid Metabolism G Chen	Cells	2021
New Insights into Multiple Sclerosis Mechanisms: Lipids on the Track to Control Inflammation and Neurodegeneration M Podbielska, J OKeeffe, A Pokryszko-Dragan	International journal of molecular sciences	2021
Novel role of xanthine oxidase-dependent H2O2 production in 12/15-lipoxygenase-mediated de novo lipogenesis, triglyceride biosynthesis and weight gain S Govatati, P Pichavaram, AM Mani, R Kumar, D Sharma, A Dienel, S Meena, MA Puchowicz, EA Park, GN Rao	Redox Biology	2021
Lipid Metabolism in Tumor Immunity Y Li		2021
Transcriptional Regulation of Metabolic Pathways via Lipid-Sensing Nuclear Receptors PPARs, FXR, and LXR in NASH M Cariello, E Piccinin, A Moschetta	CMGH Cellular and Molecular Gastroenterology and Hepatology	2021
SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogenesis by targeting key enzymatic pathways Y Majeed, N Halabi, AY Madani, R Engelke, AM Bhagwat, H Abdesselem, MV Agha, M Vakayil, R Courjaret, N Goswami, HB Hamidane, MA Elrayess, A Rafii, J Graumann, F Schmidt, NA Mazloum	Scientific Reports	2021
From Food to Genes: Transcriptional Regulation of Metabolism by Lipids and Carbohydrates I Bravo-Ruiz, MÁ Medina, B Martínez-Poveda	Nutrients	2021
Pathological Crosstalk Between Oxidized LDL and ER Stress in Human Diseases: A Comprehensive Review DS Varghese, BR Ali	Frontiers in Cell and Developmental Biology	2021
Renin-angiotensin system inhibition reverses the altered triacylglycerol metabolic network in diabetic kidney disease KM Sas, J Lin, CH Wang, H Zhang, J Saha, TM Rajendiran, T Soni, V Nair, F Eichinger, M Kretzler, FC Brosius, G Michailidis, S Pennathur	Metabolomics	2021
Transcriptional regulation of N6-methyladenosine orchestrates sex-dimorphic metabolic traits DA Salisbury, D Casero, Z Zhang, D Wang, J Kim, X Wu, L Vergnes, AH Mirza, P Leon-Mimila, KJ Williams, A Huertas-Vazquez, SR Jaffrey, K Reue, J Chen, T Sallam		2021
Statins: a repurposed drug to fight cancer W Jiang, JW Hu, XR He, WL Jin, XY He	Journal of Experimental & Clinical Cancer Research	2021
Use of Lipid-Modifying Agents for the Treatment of Glomerular Diseases M Ge, S Merscher, A Fornoni	Journal of Personalized Medicine	2021
Associations of the SREBF2 Gene and INSIG2 Polymorphisms with Obesity and Dyslipidemia in Thai Psychotic Disorder Patients Treated with Risperidone N Vanwong, C Sukasem, W Unaharassamee, N Jiratjintana, CN Nakorn, Y Hongkaew, A Puangpetch	Journal of Personalized Medicine	2021
Sterols, Oxysterols, and Accessible Cholesterol: Signalling for Homeostasis, in Immunity and During Development WJ Griffiths, Y Wang	Frontiers in physiology	2021
YiQi YangYin Decoction Attenuates Nonalcoholic Fatty Liver Disease in Type 2 Diabetes Rats F Li, G Liu, P Xue, Z Ren, P Dai, W Niu, M Xin, MM Ko	Evidence-Based Complementary and Alternative Medicine	2021
Increased Hepatic Lipogenesis Elevates Liver Cholesterol Content JM Berger, YA Moon	Molecules and Cells	2021
Fortifying Butterfat with Soybean Oil Attenuates the Onset of Diet-Induced Non-Alcoholic Steatohepatitis and Glucose Intolerance V Sánchez, A Brandt, CJ Jin, D Rajcic, AJ Engstler, F Jung, A Nier, A Baumann, I Bergheim	Nutrients	2021
Histone Deacetylase 1 Reduces Lipogenesis by Suppressing SREBP1 Transcription in Human Sebocyte Cell Line SZ95 HS Shin, Y Lee, MH Shin, SI Cho, CC Zouboulis, MK Kim, DH Lee, JH Chung	International journal of molecular sciences	2021
Evolution, Expression Profile, Regulatory Mechanism, and Functional Verification of EBP-Like Gene in Cholesterol Biosynthetic Process in Chickens (Gallus Gallus) K Jiang, Z Ma, Z Wang, H Li, Y Wang, Y Tian, D Li, X Liu	Frontiers in Genetics	2021
Amino acids-Rab1A-mTORC1 signaling controls whole-body glucose homeostasis X Zhang, X Wang, Z Yuan, SJ Radford, C Liu, SK Libutti, XF Zheng	Cell Reports	2021
Orphan Nuclear Receptor RORγ Modulates the Genome-Wide Binding of the Cholesterol Metabolic Genes during Mycotoxin-Induced Liver Injury K Li, H Li, K Zhang, J Zhang, P Hu, Y Li, H Gu, HY Liu, Z Yang, D Cai	Nutrients	2021
Role of Cholesterol and Lipid Rafts in Cancer Signaling: A Promising Therapeutic Opportunity? R Vona, E Iessi, P Matarrese	Frontiers in Cell and Developmental Biology	2021
KRAS, A Prime Mediator in Pancreatic Lipid Synthesis through Extra Mitochondrial Glutamine and Citrate Metabolism IJ Muyinda, JG Park, EJ Jang, BC Yoo	International journal of molecular sciences	2021
Lipid droplets in the nervous system I Ralhan, CL Chang, J Lippincott-Schwartz, MS Ioannou	The Journal of Cell Biology	2021
The Association between Branched-Chain Amino Acids (BCAAs) and Cardiometabolic Risk Factors in Middle-Aged Caucasian Women Stratified According to Glycemic Status J Kubacka, P Cembrowska, G Sypniewska, A Stefanska	Nutrients	2021
Dietary Fibre Modulates the Gut Microbiota P Cronin, SA Joyce, PW OToole, EM OConnor	Nutrients	2021
Function of the endolysosomal network in cholesterol homeostasis and metabolic-associated fatty liver disease (MAFLD) DY Vos, B van de Sluis	Molecular Metabolism	2021
Qki activates Srebp2-mediated cholesterol biosynthesis for maintenance of eye lens transparency S Shin, H Zhou, C He, Y Wei, Y Wang, T Shingu, A Zeng, S Wang, X Zhou, H Li, Q Zhang, Q Mo, J Long, F Lan, Y Chen, J Hu	Nature Communications	2021
Cholesterol metabolism: a new molecular switch to control inflammation D Cardoso, E Perucha	Clinical Science	2021
Anti-Obesity Effects of Morus alba L. and Aronia melanocarpa in a High-Fat Diet-Induced Obese C57BL/6J Mouse Model NY Kim, SS Thomas, DI Hwang, JH Lee, KA Kim, YS Cha	Foods	2021
Negative Regulation of Human Hepatic Constitutive Androstane Receptor by Cholesterol Synthesis Inhibition: Role of Sterol Regulatory Element Binding Proteins L Cuko, Z Duniec-Dmuchowski, EA Rondini, A Pant, JK Fallon, EM Wilson, NJ Peraino, JA Westrick, PC Smith, TA Kocarek	Drug Metabolism and Disposition	2021
Regulation of lipid metabolism by the unfolded protein response M Moncan, K Mnich, A Blomme, A Almanza, A Samali, AM Gorman	Journal of Cellular and Molecular Medicine	2021
Dipyridamole Inhibits Lipogenic Gene Expression by Retaining SCAP-SREBP in the Endoplasmic Reticulum RM Esquejo, M Roqueta-Rivera, W Shao, PE Phelan, U Seneviratne, CW am Ende, PM Hershberger, CE Machamer, PJ Espenshade, TF Osborne	Cell Chemical Biology	2021
The Chromatin Remodeling Protein BRG1 Regulates SREBP Maturation by Activating SCAP Transcription in Hepatocytes M Kong, Y Zhu, J Shao, Z Fan, Y Xu	Frontiers in Cell and Developmental Biology	2021
Iron loading induces cholesterol synthesis and sensitizes endothelial cells to TNFα-mediated apoptosis AL Fisher, DN Srole, NJ Palaskas, D Meriwether, ST Reddy, T Ganz, E Nemeth	The Journal of biological chemistry	2021
Lipid homeostasis and mevalonate pathway in COVID-19: Basic concepts and potential therapeutic targets MC Proto, D Fiore, C Piscopo, C Pagano, M Galgani, S Bruzzaniti, C Laezza, P Gazzerro, M Bifulco	Progress in Lipid Research	2021
Lipid signalling enforces functional specialization of Treg cells in tumours SA Lim, J Wei, TL Nguyen, H Shi, W Su, G Palacios, Y Dhungana, NM Chapman, L Long, J Saravia, P Vogel, H Chi	Nature	2021
Compromised Protein Prenylation as Pathogenic Mechanism in Mevalonate Kinase Deficiency FA Politiek, HR Waterham	Frontiers in immunology	2021
The Interdependency and Co-Regulation of the Vitamin D and Cholesterol Metabolism T Warren, R McAllister, A Morgan, TS Rai, V McGilligan, M Ennis, C Page, C Kelly, A Peace, BM Corfe, MM Auley, S Watterson	Cells	2021
Lipid‐based therapies against SARS‐CoV‐2 infection EH Alketbi, R Hamdy, A ElKabalawy, V Juric, M Pignitter, K Mosa, AM Almehdi, AA ElKeblawy, SS Soliman	Reviews in Medical Virology	2021
Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death N Meyer, L Henkel, B Linder, S Zielke, G Tascher, S Trautmann, G Geisslinger, C Münch, S Fulda, I Tegeder, D Kögel	Autophagy	2021
A human liver chimeric mouse model for non-alcoholic fatty liver disease B Bissig-Choisat, M Alves-Bezerra, B Zorman, SA Ochsner, M Barzi, X Legras, D Yang, M Borowiak, AM Dean, RB York, NT Galvan, J Goss, WR Lagor, DD Moore, DE Cohen, NJ McKenna, P Sumazin, KD Bissig		2021
Hepatocyte activity of the cholesterol sensor smoothened regulates cholesterol and bile acid homeostasis in mice GD Dalton, SH Oh, L Tang, S Zhang, AL Brown, V Varadharajan, C Baleanu-Gogonea, V Gogonea, P Pathak, JM Brown, AM Diehl	iScience	2021
Measurement of lipogenic flux by deuterium resolved mass spectrometry X Fu, S Deja, JA Fletcher, NN Anderson, M Mizerska, G Vale, JD Browning, JD Horton, JG McDonald, MA Mitsche, SC Burgess	Nature Communications	2021
Low-Density Lipoprotein Receptor Suppresses the Endogenous Cholesterol Synthesis Pathway To Oppose Gammaherpesvirus Replication in Primary Macrophages CA Aurubin, DA Knaack, D Sahoo, VL Tarakanova, JU Jung	Journal of virology	2021
Interplay and cooperation between SREBF1 and master transcription factors regulate lipid metabolism and tumor-promoting pathways in squamous cancer LY Li, Q Yang, YY Jiang, W Yang, Y Jiang, X Li, M Hazawa, B Zhou, GW Huang, XE Xu, S Gery, Y Zhang, LW Ding, AS Ho, ZS Zumsteg, MR Wang, MJ Fullwood, SJ Freedland, SJ Meltzer, LY Xu, EM Li, HP Koeffler, DC Lin	Nature Communications	2021
Sex‐specific effects of in vitro fertilization on adult metabolic outcomes and hepatic transcriptome and proteome in mouse L Narapareddy, EA RhonCalderon, LA Vrooman, J Baeza, DK Nguyen, C Mesaros, Y Lan, BA Garcia, RM Schultz, MS Bartolomei	The FASEB Journal	2021
The Mevalonate Pathway, a Metabolic Target in Cancer Therapy B Guerra, C Recio, H Aranda-Tavío, M Guerra-Rodríguez, JM García-Castellano, L Fernández-Pérez	Frontiers in Oncology	2021
Drosophila STING protein has a role in lipid metabolism K Akhmetova, M Balasov, I Chesnokov	eLife	2021
Cholesterol Metabolic Reprogramming in Cancer and Its Pharmacological Modulation as Therapeutic Strategy I Giacomini, F Gianfanti, MA Desbats, G Orso, M Berretta, T Prayer-Galetti, E Ragazzi, V Cocetta	Frontiers in Oncology	2021
Perinatal High-Salt Diet Induces Gut Microbiota Dysbiosis, Bile Acid Homeostasis Disbalance, and NAFLD in Weanling Mice Offspring Q Guo, Y Tang, Y Li, Z Xu, D Zhang, J Liu, X Wang, W Xia, S Xu	Nutrients	2021
NRF3 upregulates gene expression in SREBP2-dependent mevalonate pathway with cholesterol uptake and lipogenesis inhibition T Waku, T Hagiwara, N Tamura, Y Atsumi, Y Urano, M Suzuki, T Iwami, K Sato, M Yamamoto, N Noguchi, A Kobayashi	iScience	2021
A novel MBTPS2 variant associated with BRESHECK syndrome impairs sterol‐regulated transcription and the endoplasmic reticulum stress response A Strong, ME March, CJ Cardinale, SE Kim, J Merves, H Whitworth, L Raffini, C Larosa, L Copelovitch, C Hou, D Slater, C Vaccaro, D Watson, EH Zackai, J Billheimer, H Hakonarson	American journal of medical genetics. Part A	2021
Silencing of the ER and Integrative Stress Responses in the Liver of Mice with Error-Prone Translation J Moore, I Osinnii, A Grimm, B Oettinghaus, A Eckert, S Frank, EC Böttger	Cells	2021
Induction of SREBP1 degradation coupled with suppression of SREBP1-mediated lipogenesis impacts the response of EGFR mutant NSCLC cells to osimertinib Z Chen, D Yu, TK Owonikoko, SS Ramalingam, SY Sun	Oncogene	2021
Phosphoenolpyruvate carboxykinase in cell metabolism: Roles and mechanisms beyond gluconeogenesis S Yu, S Meng, M Xiang, H Ma	Molecular Metabolism	2021
UV-Induced Reduction of ACVR1C Decreases SREBP1 and ACC Expression by the Suppression of SMAD2 Phosphorylation in Normal Human Epidermal Keratinocytes YD Tian, MH Chung, QL Quan, DH Lee, EJ Kim, JH Chung	International journal of molecular sciences	2021
A Systems Approach Dissociates Fructose-Induced Liver Triglyceride from Hypertriglyceridemia and Hyperinsulinemia in Male Mice L Doridot, SA Hannou, SA Krawczyk, W Tong, MS Kim, GS McElroy, AJ Fowler, II Astapova, MA Herman	Nutrients	2021
Alteration in Cellular Signaling and Metabolic Reprogramming during Viral Infection A Pant, L Dsouza, Z Yang, B Gewurz, VR Prasad	mBio	2021
Fasting increases 18:2-containing phosphatidylcholines to complement the decrease in 22:6-containing phosphatidylcholines in mouse skeletal muscle N Senoo, T Akahori, H Ichida, N Miyoshi, A Morita, T Shimizu, H Shindou, S Miura, RE Duncan	PloS one	2021
Qki regulates myelinogenesis through Srebp2-dependent cholesterol biosynthesis X Zhou, S Shin, C He, Q Zhang, MN Rasband, J Ren, C Dai, RI Zorrilla-Veloz, T Shingu, L Yuan, Y Wang, Y Chen, F Lan, J Hu	eLife	2021
A targeted multi-omics approach reveals paraoxonase-1 as a determinant of obesity-associated fatty liver disease S Diels, B Cuypers, A Tvarijonaviciute, B Derudas, EV Dijck, A Verrijken, LF Gaal, K Laukens, P Lefebvre, JJ Ceron, S Francque, WV Berghe, WV Hul	Clinical Epigenetics	2021
The prorenin receptor and its soluble form contribute to lipid homeostasis E Gatineau, G Arthur, A Poupeau, K Nichols, BT Spear, NR Shelman, GA Graf, RE Temel, FB Yiannikouris	American journal of physiology. Endocrinology and metabolism	2021
TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination WY Ho, JC Chang, K Lim, A Cazenave-Gassiot, AT Nguyen, JC Foo, S Muralidharan, A Viera-Ortiz, SJ Ong, JH Hor, I Agrawal, S Hoon, OA Arogundade, MJ Rodriguez, SM Lim, SH Kim, J Ravits, SY Ng, MR Wenk, EB Lee, G Tucker-Kellogg, SC Ling	The Journal of Cell Biology	2021
Neurotrophins as Key Regulators of Cell Metabolism: Implications for Cholesterol Homeostasis M Colardo, N Martella, D Pensabene, S Siteni, SD Bartolomeo, V Pallottini, M Segatto	International journal of molecular sciences	2021
The antiviral effect of metformin on zika and dengue virus infection CN Farfan-Morales, CD Cordero-Rivera, JF Osuna-Ramos, IE Monroy-Muñoz, LA Jesús-González, JE Muñoz-Medina, AM Hurtado-Monzón, JM Reyes-Ruiz, RM del Ángel	Scientific Reports	2021
Chronic Oleoylethanolamide Treatment Decreases Hepatic Triacylglycerol Level in Rat Liver by a PPARγ/SREBP-Mediated Suppression of Fatty Acid and Triacylglycerol Synthesis A Romano, M Friuli, LD Coco, S Longo, D Vergara, PD Boccio, S Valentinuzzi, I Cicalini, FP Fanizzi, S Gaetani, AM Giudetti	Nutrients	2021
Loss of lysophosphatidic acid receptor 1 in hepatocytes reduces steatosis via down-regulation of CD36 I Lua, S Balog, A Yanagi, C Tateno, K Asahina	Prostaglandins & Other Lipid Mediators	2021
Long-Term Disturbed Expression and DNA Methylation of SCAP/SREBP Signaling in the Mouse Lung From Assisted Reproductive Technologies F Le, N Wang, Q Wang, X Yang, L Li, L Wang, X Liu, M Hu, F Jin, H Lou	Frontiers in Genetics	2021
Differential gene expression analysis of palbociclib-resistant TNBC via RNA-seq L Lanceta, N Lypova, C ONeill, X Li, E Rouchka, J Chesney, Y Imbert-Fernandez	Breast Cancer Research and Treatment	2021
Contradictory roles of lipid metabolism in immune response within the tumor microenvironment W Yu, Q Lei, L Yang, G Qin, S Liu, D Wang, Y Ping, Y Zhang	Journal of Hematology & Oncology	2021
Dietary Nano-ZnO Is Absorbed via Endocytosis and ZIP Pathways, Upregulates Lipogenesis, and Induces Lipotoxicity in the Intestine of Yellow Catfish SW Chen, WH Lv, K Wu, GH Chen, F Chen, CC Song, Z Luo	International journal of molecular sciences	2021
MMAB promotes negative feedback control of cholesterol homeostasis L Goedeke, A Canfrán-Duque, N Rotllan, B Chaube, BM Thompson, RG Lee, GW Cline, JG McDonald, GI Shulman, MA Lasunción, Y Suárez, C Fernández-Hernando	Nature Communications	2021
MOVAS Cells: A Versatile Cell Line for Studying Vascular Smooth Muscle Cell Cholesterol Metabolism I Esobi, C Barksdale, C HeardTate, R Powell, T Bruce, A Stamatikos	Lipids	2021
GH directly inhibits steatosis and liver injury in a sex-dependent and IGF1-independent manner A Sarmento-Cabral, M del Rio-Moreno, MC Vazquez-Borrego, M Mahmood, E Gutierrez-Casado, N Pelke, G Guzman, PV Subbaiah, J Cordoba-Chacon, S Yakar, RD Kineman	Journal of Endocrinology	2021
Lactate dehydrogenase B regulates macrophage metabolism in the tumor microenvironment AC Frank, R Raue, DC Fuhrmann, E Sirait-Fischer, C Reuse, A Weigert, D Lütjohann, K Hiller, SN Syed, B Brüne	Theranostics	2021
Ectodysplasin A/Ectodysplasin A Receptor System and Their Roles in Multiple Diseases Z Cai, X Deng, J Jia, D Wang, G Yuan	Frontiers in physiology	2021
Dyslipidemia in Chinese Pancreatic Cancer Patients: A Two-Center Retrospective Study F Wang, L Huang, J Zhang, J Fan, H Wu, J Xu	Journal of Cancer	2021
Hepatic metabolic regulation by nuclear factor E4BP4 Z Zhao, L Yin, F Wu, X Tong	Journal of Molecular Endocrinology	2021
Close interactions between lncRNAs, lipid metabolism and ferroptosis in cancer J Huang, J Wang, H He, Z Huang, S Wu, C Chen, W Liu, L Xie, Y Tao, L Cong, Y Jiang	International journal of biological sciences	2021
Perspective: The Saturated Fat–Unsaturated Oil Dilemma: Relations of Dietary Fatty Acids and Serum Cholesterol, Atherosclerosis, Inflammation, Cancer, and All-Cause Mortality Lawrence GD	Advances in Nutrition	2021
Lactobacillus mediates the expression of NPC1L1, CYP7A1, and ABCG5 genes to regulate cholesterol. Cao K, Zhang K, Ma M, Ma J, Tian J, Jin Y	Food Science & Nutrition	2021
Modulation of hepatic miRNA expression in Atlantic salmon (Salmo salar) by family background and dietary fatty acid composition. Østbye TK, Woldemariam NT, Lundberg CE, Berge GM, Ruyter B, Andreassen R	Journal of Fish Biology	2021
The Mechanism of Honey in Reversing Metabolic Syndrome. Hashim KN, Chin KY, Ahmad F	Molecules (Basel, Switzerland)	2021
Targeting the PI3K/Akt/mTOR Pathway in Hepatocellular Carcinoma. Sun EJ, Wankell M, Palamuthusingam P, McFarlane C, Hebbard L	Biomedicines	2021
NAFLD in type 1 diabetes: overrated or underappreciated? Mertens J, Van Gaal LF, Francque SM, De Block C	Therapeutic Advances in Endocrinology and Metabolism	2021
Pathophysiological Potentials of NRF3-Regulated Transcriptional Axes in Protein and Lipid Homeostasis. Waku T, Kobayashi A	International journal of molecular sciences	2021
Oral administration of Jinan Red Ginseng and licorice extract mixtures ameliorates nonalcoholic steatohepatitis by modulating lipogenesis. Yang D, Jeong H, Hwang SM, Kim JW, Moon HW, Lee YE, Oh HB, Park CB, Kim B	Journal of Ginseng Research	2021
Lipid-Lowering Effects of Inonotus obliquus Polysaccharide In Vivo and In Vitro. Yang M, Hu D, Cui Z, Li H, Man C, Jiang Y		2021
Raphani Semen (Raphanus sativus L.) Ameliorates Alcoholic Fatty Liver Disease by Regulating De Novo Lipogenesis. Park WY, Song G, Noh JH, Kim T, Kim JJ, Hong S, Park J, Um JY	Nutrients	2021
Aberrant lipid metabolism reprogramming and immune microenvironment for gastric cancer: a literature review. Cui MY, Yi X, Zhu DX, Wu J	Translational cancer research	2021
Gene expression and functional abnormalities in XX/Sry Leydig cells Yanai S, Baba T, Inui K, Miyabayashi K, Han S, Inoue M, Takahashi F, Kanai Y, Ohkawa Y, Choi MH, Morohashi KI	Scientific Reports	2021
Ferulic Acid Ameliorates Atherosclerotic Injury by Modulating Gut Microbiota and Lipid Metabolism Gu Y, Zhang Y, Li M, Huang Z, Jiang J, Chen Y, Chen J, Jia Y, Zhang L, Zhou F	Frontiers in pharmacology	2021
4β-Hydroxycholesterol is a prolipogenic factor that promotes SREBP1c expression and activity through the liver X receptor Moldavski O, Zushin PJ, Berdan CA, Van Eijkeren RJ, Jiang X, Qian M, Ory DS, Covey DF, Nomura DK, Stahl A, Weiss EJ, Zoncu R	Journal of lipid research	2021
Diverse Functions of Tim50, a Component of the Mitochondrial Inner Membrane Protein Translocase Chaudhuri M, Tripathi A, Gonzalez FS	International journal of molecular sciences	2021
The Role of Mfsd2a in Nervous System Diseases Huang B, Li X	Frontiers in neuroscience	2021
Identification of pimavanserin tartrate as a potent Ca2+-calcineurin-NFAT pathway inhibitor for glioblastoma therapy Liu ZZ, Liu XN, Fan RC, Jia YP, Zhang QK, Gao XQ, Wang YQ, Yang MQ, Ji LZ, Zhou YQ, Li HL, Li P, Tang B	Acta Pharmacologica Sinica	2021
Development and validation of a four‐lipid metabolism gene signature for diagnosis of pancreatic cancer Ye Y, Chen Z, Shen Y, Qin Y, Wang H	FEBS Open Bio	2021
Carnitine Orotate Complex Ameliorates Insulin Resistance and Hepatic Steatosis Through Carnitine Acetyltransferase Pathway Hong JH, Lee MK	Diabetes & Metabolism Journal	2021
Sulforaphane Attenuates Nonalcoholic Fatty Liver Disease by Inhibiting Hepatic Steatosis and Apoptosis Li J, Xie S, Teng W	Nutrients	2021
Advances in analyzing the breast cancer lipidome and its relevance to disease progression and treatment Ward AV, Anderson SM, Sartorius CA	Journal of Mammary Gland Biology and Neoplasia	2021
An RNAi therapeutic targeting hepatic DGAT2 in a genetically obese mouse model of nonalcoholic steatohepatitis Yenilmez B, Wetoska N, Kelly M, Echeverria D, Min K, Lifshitz L, Alterman JF, Hassler MR, Hildebrand S, DiMarzio C, McHugh N, Vangjeli L, Sousa J, Pan M, Han X, Brehm MA, Khvorova A, Czech MP	Molecular Therapy	2021
Human-Relevant Mechanisms and Risk Factors for TAK-875-Induced Liver Injury Identified via a Gene Pathway-Based Approach in Collaborative Cross Mice Mosedale M, Cai Y, Eaddy JS, Kirby PJ, Wolenski FS, Dragan Y, Valdar W	Toxicology	2021
Why is elevation of serum cholesterol associated with exposure to perfluoroalkyl substances (PFAS) in humans? A workshop report on potential mechanisms Andersen ME, Hagenbuch B, Apte U, Corton JC, Fletcher T, Lau C, Roth WL, Staels B, Vega GL, Clewell HJ 3rd, Longnecker MP	Toxicology	2021
Fatty acid metabolism in adaptive immunity Zhou X, Zhu X, Zeng H	The FEBS journal	2021
The role of lipid metabolism in shaping the expansion and the function of regulatory T cells Pinzon Grimaldos A, Bini S, Pacella I, Rossi A, Di Costanzo A, Minicocci I, D\u2019Erasmo L, Arca M, Piconese S	Clinical & Experimental Immunology	2021
Dietary Olive Oil Intake Improves Running Endurance with Intramuscular Triacylglycerol Accumulation in Mice. Komiya Y, Sugiyama M, Ochiai M, Osawa N, Adachi Y, Iseki S, Arihara K	Nutrients	2021
Dual Switch in Lipid Metabolism in Cervical Epithelial Cells during Dysplasia Development Observed Using Raman Microscopy and Molecular Methods. Sitarz K, Czamara K, Bialecka J, Klimek M, Szostek S, Kaczor A	Cancers	2021
Inositol triphosphate-triggered calcium release blocks lipid exchange at endoplasmic reticulum-Golgi contact sites. Malek M, Wawrzyniak AM, Koch P, Lüchtenborg C, Hessenberger M, Sachsenheimer T, Jang W, Brügger B, Haucke V	Nature Communications	2021
PRL-1 overexpressed placenta-derived mesenchymal stem cells suppress adipogenesis in Graves' ophthalmopathy through SREBP2/HMGCR pathway. Park M, Kim JY, Kang JM, Lee HJ, Banga JP, Kim GJ, Lew H	Stem Cell Research & Therapy	2021
Phytobiotics with Adsorbent to Mitigate Toxicity of Multiple Mycotoxins on Health and Growth of Pigs Holanda DM, Kim YI, Parnsen W, Kim SW	Toxins	2021
The Cholesterol-Lowering Effect of Capsella Bursa-Pastoris Is Mediated via SREBP2 and HNF-1α-Regulated PCSK9 Inhibition in Obese Mice and HepG2 Cells Hwang JT, Choi E, Choi HK, Park JH, Chung MY	Foods	2021
Ameliorative effects of functional crude-chalaza hydrolysates on the hepatosteatosis development induced by a high-fat diet Chen JW, Lin YL, Samuel Wu YH, Wang SY, Chou CH, Chen YC	Poultry science	2021
Combination Treatment of Arazyme and Soy Leaf Extract Attenuates Hyperglycemia and Hepatic Steatosis in High-Fat Diet-Fed C57BL/6J Mice Lee H, Cho S, Kang A, Shin DH, Park HY, Jeong TS	Life Sciences	2021
PKM2‐TMEM33 axis regulates lipid homeostasis in cancer cells by controlling SCAP stability Liu F, Ma M, Gao A, Ma F, Ma G, Liu P, Jia C, Wang Y, Donahue K, Zhang S, Ong IM, Keles S, Li L, Xu W	The EMBO Journal	2021
The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals. Torrence ME, MacArthur MR, Hosios AM, Valvezan AJ, Asara JM, Mitchell JR, Manning BD	eLife	2021
Rubus chingii var. suavissimus alleviates high-fat diet-induced lipid metabolism disorder via modulation of the PPARs/SREBP pathway in Syrian golden hamsters. Jiang MJ, Li L, Huang WF, Su J, Li YH, Qu XS, Fan LL	Journal of Natural Medicines	2021
Scap structures highlight key role for rotation of intertwined luminal loops in cholesterol sensing. Kober DL, Radhakrishnan A, Goldstein JL, Brown MS, Clark LD, Bai XC, Rosenbaum DM	Cell	2021
Nuciferine protects against high-fat diet-induced hepatic steatosis and insulin resistance via activating TFEB-mediated autophagy–lysosomal pathway Du X, Di Malta C, Fang Z, Shen T, Niu X, Chen M, Jin B, Yu H, Lei L, Gao W, Song Y, Wang Z, Xu C, Cao Z, Liu G, Li X	Acta pharmaceutica Sinica. B	2021
Protein disulfide isomerase A3 might be involved in the regulation of 24-dehydrocholesterol reductase via vitamin D equilibrium in primary cortical neurons. Yavuz U, Alaylıoğlu M, Şengül B, Karras SN, Gezen-Ak D, Dursun E	In vitro cellular & developmental biology. Animal	2021
Regulation of Plasma Membrane Sterol Homeostasis by Nonvesicular Lipid Transport Zheng Koh DH, Saheki Y		2021
Protein arginine methyltransferase 5 promotes cholesterol biosynthesis-mediated Th17 responses and autoimmunity Lindsay M Webb, Shouvonik Sengupta, Claudia Edell, Zayda Piedra-Quintero, Stephanie A. Amici, Janiret Narvaez-Miranda, Makenzie Bevins, Austin Kennemer, Georgios I. Laliotis, Philip Tsichlis, Mireia Guerau-de-Arellano	Journal of Clinical Investigation	2020
Dengue virus induces PCSK9 expression to alter antiviral responses and disease outcomes Esther S. Gan, Hwee Cheng Tan, Huynh Le Thi Duyen, Huynh Trung Trieu, Bridget Wills, Eng Eong Ooi, Nabil G. Seidah, Sophie Yacoub	Journal of Clinical Investigation	2020
COVID-19-activated SREBP2 disturbs cholesterol biosynthesis and leads to cytokine storm W Lee, JH Ahn, HH Park, HN Kim, H Kim, Y Yoo, H Shin, KS Hong, JG Jang, CG Park, EY Choi, JS Bae, YK Seo	Signal Transduction and Targeted Therapy	2020
Collaborative interactions of heterogenous ribonucleoproteins contribute to transcriptional regulation of sterol metabolism in mice Z Zhang, AC Feng, D Salisbury, X Liu, X Wu, J Kim, I Lapina, D Wang, B Lee, J Fraga, C Pan, KJ Williams, AJ Lusis, P Scumpia, T Sallam	Nature Communications	2020
Endothelial cell and T‐cell crosstalk: Targeting metabolism as a therapeutic approach in chronic inflammation M Certo, H Elkafrawy, V Pucino, D Cucchi, KC Cheung, C Mauro	British Journal of Pharmacology	2020
Preclinical and Clinical Development of Noncoding RNA Therapeutics for Cardiovascular Disease CK Huang, S Kafert-Kasting, T Thum	Circulation research	2020
Transcriptional Regulation in Non-Alcoholic Fatty Liver Disease S Steensels, J Qiao, BA Ersoy	Metabolites	2020
Signaling networks in immunometabolism J Saravia, JL Raynor, NM Chapman, SA Lim, H Chi	Cell Research	2020
New Insights on the Role of Lipid Metabolism in the Metabolic Reprogramming of Macrophages A Batista-Gonzalez, R Vidal, A Criollo, LJ Carreño	Frontiers in immunology	2020
Role of de novo cholesterol synthesis enzymes in cancer J Yang, L Wang, R Jia	Journal of Cancer	2020
Fructose and hepatic insulin resistance S Softic, KL Stanhope, J Boucher, S Divanovic, MA Lanaspa, RJ Johnson, CR Kahn	Critical Reviews in Clinical Laboratory Sciences	2020
Targeting Metabolism in Cancer Cells and the Tumour Microenvironment for Cancer Therapy J Li, JQ Eu, LR Kong, L Wang, YC Lim, BC Goh, AL Wong	Molecules (Basel, Switzerland)	2020
Leptin Receptors in RIP-Cre25Mgn Neurons Mediate Anti-dyslipidemia Effects of Leptin in Insulin-Deficient Mice A Singha, JP Palavicini, M Pan, S Farmer, D Sandoval, X Han, T Fujikawa	Frontiers in Endocrinology	2020
Physiological Disturbance in Fatty Liver Energy Metabolism Converges on IGFBP2 Abundance and Regulation in Mice and Men P Fahlbusch, B Knebel, T Hörbelt, DM Barbosa, A Nikolic, S Jacob, H Al-Hasani, FV de Velde, YV Nieuwenhove, D Müller-Wieland, B Lapauw, DM Ouwens, J Kotzka	International journal of molecular sciences	2020
Pathophysiology of NAFLD and NASH in Experimental Models: The Role of Food Intake Regulating Peptides L Kořínková, V Pražienková, L Černá, A Karnošová, B Železná, J Kuneš, L Maletínská	Frontiers in Endocrinology	2020
Why Hepatic CYP2E1-Elevation by Itself Is Insufficient for Inciting NAFLD/NASH: Inferences from Two Genetic Knockout Mouse Models MA Correia, D Kwon	Biology : open access journal	2020
Lemon Balm and Its Constituent, Rosmarinic Acid, Alleviate Liver Damage in an Animal Model of Nonalcoholic Steatohepatitis M Kim, GH Yoo, A Randy, YJ Son, CR Hong, SM Kim, CW Nho	Nutrients	2020
Pineapple Vinegar Regulates Obesity-Related Genes and Alters the Gut Microbiota in High-Fat Diet (HFD) C57BL/6 Obese Mice NE Mohamad, SK Yeap, H Ky, NW Liew, BK Beh, SY Boo, WY Ho, SA Sharifuddin, K Long, NB Alitheen	Evidence-Based Complementary and Alternative Medicine	2020
Diet-Induced Physiological Responses in the Liver of Atlantic Salmon (Salmo salar) Inferred Using Multiplex PCR Platforms A Caballero-Solares, , BM Cleveland, MB Foroutani, CC Parrish, RG Taylor, ML Rise	Marine Biotechnology	2020
Non-Coding and Regulatory RNAs as Epigenetic Remodelers of Fatty Acid Homeostasis in Cancer S Cruz-Gil, LP Fernández, R Sánchez-Martínez, MG de Cedrón, AR de Molina	Cancers	2020
Novel cholesterol‐dependent regulation of cardiac K ATP subunit expression revealed using histone deacetylase inhibitors R Geiger, N Fatima, JF Schooley, JT Smyth, MC Haigney, TP Flagg	Physiological Reports	2020
The Molecular Mechanisms by Which Vitamin D Prevents Insulin Resistance and Associated Disorders I Szymczak-Pajor, J Drzewoski, A Śliwińska	International journal of molecular sciences	2020
The emerging role of long noncoding RNAs in normal liver function, disease and malignancy A Mahpour, AC Mullen		2020
In Steatotic Cells, ATP-Citrate Lyase mRNA Is Efficiently Translated through a Cap-Independent Mechanism, Contributing to the Stimulation of De Novo Lipogenesis L Siculella, L Giannotti, M Testini, GV Gnoni, F Damiano	International journal of molecular sciences	2020
Chronic Microcystin-LR Exposure Induces Abnormal Lipid Metabolism via Endoplasmic Reticulum Stress in Male Zebrafish D Zhang, W Lin, Y Liu, H Guo, L Wang, L Yang, L Li, D Li, R Tang	Toxins	2020
Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism A Loregger, M Raaben, J Nieuwenhuis, JM Tan, LT Jae, LG van den Hengel, S Hendrix, M van den Berg, S Scheij, JY Song, IJ Huijbers, LJ Kroese, R Ottenhoff, M van Weeghel, B van de Sluis, T Brummelkamp, N Zelcer	Nature Communications	2020
Cholesterol metabolism regulation mediated by SREBP-2, LXRα and miR-33a in rainbow trout (Oncorhynchus mykiss) both in vivo and in vitro T Zhu, G Corraze, E Plagnes-Juan, S Skiba-Cassy, TY Chen	PloS one	2020
Ascorbate protects liver from metabolic disorder through inhibition of lipogenesis and suppressor of cytokine signaling 3 (SOCS3) Y Xu, Y Wu, Y Xiong, J Tao, T Pan, S Tan, G Gao, Y Chen, N Abbas, A Getachew, Y Zhuang, K You, F Yang, Y Li	Nutrition & Metabolism	2020
Fatty liver diseases, mechanisms, and potential therapeutic plant medicines JZ ZHU, HW YI, W HUANG, T PANG, HP ZHOU, XD WU	Chinese Journal of Natural Medicines	2020
Excessive BCAA regulates fat metabolism partially through the modification of m6A RNA methylation in weanling piglets J Heng, Z Wu, M Tian, J Chen, H Song, F Chen, W Guan, S Zhang	Nutrition & Metabolism	2020
mTOR at the nexus of nutrition, growth, ageing and disease GY Liu, DM Sabatini	Nature Reviews Molecular Cell Biology	2020
AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice ME Ertunc, BP Kok, WH Parsons, JG Wang, D Tan, CJ Donaldson, AF Pinto, JM Vaughan, N Ngo, KM Lum, CL Henry, AR Coppola, MJ Niphakis, BF Cravatt, E Saez, A Saghatelian	The Journal of biological chemistry	2020
Wntless regulates lipogenic gene expression in adipocytes and protects against diet-induced metabolic dysfunction DP Bagchi, Z Li, CA Corsa, J Hardij, H Mori, BS Learman, KT Lewis, RL Schill, SM Romanelli, OA MacDougald	Molecular Metabolism	2020
Long term N-acetylcysteine administration rescues liver steatosis via endoplasmic reticulum stress with unfolded protein response in mice CC Tsai, YJ Chen, HR Yu, LT Huang, YL Tain, IC Lin, JM Sheen, PW Wang, MM Tiao	Lipids in Health and Disease	2020
Whole blood transcriptional responses of very preterm infants during late-onset sepsis S Ng, T Strunk, AH Lee, EE Gill, R Falsafi, T Woodman, J Hibbert, RE Hancock, A Currie, FJ Esteban	PloS one	2020
Peripheral circadian rhythms in the liver and white adipose tissue of mice are attenuated by constant light and restored by time-restricted feeding D Yamamuro, M Takahashi, S Nagashima, T Wakabayashi, H Yamazaki, A Takei, S Takei, K Sakai, K Ebihara, Y Iwasaki, T Yada, S Ishibashi, H Guillou	PloS one	2020
Deciphering Macrophage Phenotypes upon Lipid Uptake and Atherosclerosis J Lee, JH Choi	Immune Network	2020
Peroxisome Proliferator-Activated Receptors and Their Novel Ligands as Candidates for the Treatment of Non-Alcoholic Fatty Liver Disease A Fougerat, A Montagner, N Loiseau, H Guillou, W Wahli	Cells	2020
Regulation of Glucose and Lipid Metabolism by Long Non-coding RNAs: Facts and Research Progress TN Zhang, W Wang, N Yang, XM Huang, CF Liu	Frontiers in Endocrinology	2020
Hyperglycemia-stimulating diet induces liver steatosis in sheep M Kalyesubula, R Mopuri, A Rosov, T Alon, N Edery, U Moallem, H Dvir	Scientific Reports	2020
POST1/C12ORF49 regulates the SREBP pathway by promoting site-1 protease maturation J Xiao, Y Xiong, LT Yang, JQ Wang, ZM Zhou, LW Dong, XJ Shi, X Zhao, J Luo, BL Song	Protein & Cell	2020
Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention L Butler, Y Perone, J Dehairs, LE Lupien, V de Laat, A Talebi, M Loda, WB Kinlaw, JV Swinnen	Advanced Drug Delivery Reviews	2020
Hepatic Levels of DHA-Containing Phospholipids Instruct SREBP1-Mediated Synthesis and Systemic Delivery of Polyunsaturated Fatty Acids D Hishikawa, K Yanagida, K Nagata, A Kanatani, Y Iizuka, F Hamano, M Yasuda, T Okamura, H Shindou, T Shimizu	iScience	2020
Pathophysiology of Type 2 Diabetes Mellitus U Galicia-Garcia, A Benito-Vicente, S Jebari, A Larrea-Sebal, H Siddiqi, KB Uribe, H Ostolaza, C Martín	International journal of molecular sciences	2020
Beneficial Effects of Newly Isolated Akkermansia muciniphila Strains from the Human Gut on Obesity and Metabolic Dysregulation M Yang, S Bose, S Lim, JG Seo, JH Shin, D Lee, WH Chung, EJ Song, YD Nam, H Kim	Microorganisms	2020
Diverse Immunoregulatory Roles of Oxysterols—The Oxidized Cholesterol Metabolites C Choi, DK Finlay	Metabolites	2020
Liver X Receptors: Regulators of Cholesterol Metabolism, Inflammation, Autoimmunity, and Cancer MT Bilotta, S Petillo, A Santoni, M Cippitelli	Frontiers in immunology	2020
Iron Chaperone Poly rC Binding Protein 1 Protects Mouse Liver From Lipid Peroxidation and Steatosis O Protchenko, E Baratz, S Jadhav, F Li, M ShakouryElizeh, O Gavrilova, MC Ghosh, JE Cox, JA Maschek, VA Tyurin, YY Tyurina, H Bayir, AT Aron, CJ Chang, VE Kagan, CC Philpott	Hepatology	2020
Functional Peroxisomes Are Essential for Efficient Cholesterol Sensing and Synthesis KN Charles, JE Shackelford, PL Faust, SJ Fliesler, H Stangl, WJ Kovacs	Frontiers in Cell and Developmental Biology	2020
Membrane heist: Coronavirus host membrane remodeling during replication J Zhang, Y Lan, S Sanyal	Biochimie	2020
The Effect of Inflammation and Insulin Resistance on Lipid and Lipoprotein Responsiveness to Dietary Intervention KS Petersen, KJ Bowen, AM Tindall, VK Sullivan, EA Johnston, JA Fleming, PM Kris-Etherton		2020
Nonalcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis: Current Issues and Future Perspectives in Preclinical and Clinical Research C Berardo, LG Pasqua, M Cagna, P Richelmi, M Vairetti, A Ferrigno	International journal of molecular sciences	2020
Playing Jekyll and Hyde—The Dual Role of Lipids in Fatty Liver Disease MR Molenaar, LC Penning, JB Helms	Cells	2020
Modulation of Fatty Acid-Related Genes in the Response of H9c2 Cardiac Cells to Palmitate and n-3 Polyunsaturated Fatty Acids S Cetrullo, S DAdamo, V Panichi, RM Borzì, C Pignatti, F Flamigni	Cells	2020
Role of Elevated Intracellular S-Adenosylhomocysteine in the Pathogenesis of Alcohol-Related Liver Disease MK Arumugam, S Talawar, L Listenberger, TM Donohue, NA Osna, KK Kharbanda	Cells	2020
Investigation of the Efficacy of a Postbiotic Yeast Cell Wall-Based Blend on Newly-Weaned Pigs under a Dietary Challenge of Multiple Mycotoxins with Emphasis on Deoxynivalenol DM Holanda, A Yiannikouris, SW Kim	Toxins	2020
Lipid Metabolism in Development and Progression of Hepatocellular Carcinoma M Sangineto, R Villani, F Cavallone, A Romano, D Loizzi, G Serviddio	Cancers	2020
Extra Virgin Olive Oil Phenol Extracts Exert Hypocholesterolemic Effects through the Modulation of the LDLR Pathway: In Vitro and Cellular Mechanism of Action Elucidation C Lammi, M Bellumori, L Cecchi, M Bartolomei, C Bollati, ML Clodoveo, F Corbo, A Arnoldi, N Mulinacci	Nutrients	2020
Loss of HNF1α Function Contributes to Hepatocyte Proliferation and Abnormal Cholesterol Metabolism via Downregulating miR-122: A Novel Mechanism of MODY3 M Hu, X Huang, X Han, L Ji	Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy	2020
The Vicious Cycle of Renal Lipotoxicity and Mitochondrial Dysfunction M Ge, F Fontanesi, S Merscher, A Fornoni	Frontiers in physiology	2020
Influences of glycyrrhetinic acid (GA) dietary supplementation on growth, feed utilization, and expression of lipid metabolism genes in channel catfish (Ictalurus punctatus) fed a high-fat diet HE Desouky, G Jiang, D Zhang, KP Abasubong, X Yuan, X Li, W Liu	Fish Physiology and Biochemistry	2020
Brahma Related Gene 1 (Brg1) Regulates Cellular Cholesterol Synthesis by Acting as a Co-factor for SREBP2 Z Fan, M Kong, M Li, W Hong, X Fan, Y Xu	Frontiers in Cell and Developmental Biology	2020
Transcriptome Profiling Reveals Novel Candidate Genes Related to Hippocampal Dysfunction in SREBP-1c Knockout Mice MJ Ang, J Kim, S Lee, SH Kim, JC Kim, TI Jeon, SS Im, C Moon	International journal of molecular sciences	2020
Beneficial Effects of SREBP Decoy Oligodeoxynucleotide in an Animal Model of Hyperlipidemia HJ An, JY Kim, MG Gwon, H Gu, HJ Kim, J Leem, SW Youn, KK Park	International journal of molecular sciences	2020
SREBP1 regulates mitochondrial metabolism in oncogenic KRAS expressing NSCLC CF Ruiz, ED Montal, JA Haley, AJ Bott, JD Haley	The FASEB Journal	2020
Targeting SREBP-2-Regulated Mevalonate Metabolism for Cancer Therapy L Xue, H Qi, H Zhang, L Ding, Q Huang, D Zhao, BJ Wu, X Li	Frontiers in Oncology	2020
SOAT1 promotes mevalonate pathway dependency in pancreatic cancer TE Oni, G Biffi, LA Baker, Y Hao, C Tonelli, TD Somerville, A Deschênes, P Belleau, C Hwang, FJ Sánchez-Rivera, H Cox, E Brosnan, A Doshi, RP Lumia, K Khaledi, Y Park, LC Trotman, SW Lowe, A Krasnitz, CR Vakoc, DA Tuveson	Journal of Experimental Medicine	2020
Synergistic Effect of Omega-3 Fatty Acids and Oral-Hypoglycemic Drug on Lipid Normalization through Modulation of Hepatic Gene Expression in High Fat Diet with Low Streptozotocin-Induced Diabetic Rats S Khadke, P Mandave, A Kuvalekar, V Pandit, M Karandikar, N Mantri	Nutrients	2020
Recent Insights Into SREBP as a Direct Mediator of Kidney Fibrosis via Lipid-Independent Pathways D Dorotea, D Koya, H Ha	Frontiers in pharmacology	2020
Time-Restricted Feeding Reduces the Detrimental Effects of a High-Fat Diet, Possibly by Modulating the Circadian Rhythm of Hepatic Lipid Metabolism and Gut Microbiota Y Ye, H Xu, Z Xie, L Wang, Y Sun, H Yang, D Hu, Y Mao	Frontiers in Nutrition	2020
Grape seed proanthocyanidin extract ameliorates hepatic lipid accumulation and inflammation in grass carp (Ctenopharyngodon idella) RH Lu, CB Qin, F Yang, WY Zhang, YR Zhang, GK Yang, LP Yang, XL Meng, X Yan, GX Nie	Fish Physiology and Biochemistry	2020
Insights into the Role of Estrogen Receptor β in Triple-Negative Breast Cancer A Sellitto, Y DAgostino, E Alexandrova, J Lamberti, G Pecoraro, D Memoli, D Rocco, E Coviello, G Giurato, G Nassa, R Tarallo, A Weisz, F Rizzo	Cancers	2020
Neuronal modulation of hepatic lipid accumulation induced by bingelike drinking M Ibars, MT Maier, E Yulyaningsih, L Perez, R Cheang, A Vilhelmsson, SM Louie, SA Wegner, X Yuan, HK Eltzschig, FW Hopf, DK Nomura, SK Koliwad, AW Xu	American journal of physiology. Endocrinology and metabolism	2020
Stress relief for cancer immunotherapy: implications for the ER stress response in tumor immunity AM Andrews, MD Tennant, JE Thaxton	Cancer Immunology, Immunotherapy	2020
PAS Kinase: A Nutrient and Energy Sensor “Master Key” in the Response to Fasting/Feeding Conditions V Hurtado-Carneiro, A Pérez-García, E Alvarez, C Sanz	Frontiers in Endocrinology	2020
Potential roles of bone morphogenetic protein-9 in glucose and lipid homeostasis Y Wang, C Ma, T Sun, L Ren	Journal of Physiology and Biochemistry	2020
Lipid Regulatory Proteins as Potential Therapeutic Targets for Ovarian Cancer in Obese Women J Yang, MS Stack	Cancers	2020
Bone marrow deficiency of mRNA decaying protein Tristetraprolin increases inflammation and mitochondrial ROS but reduces hepatic lipoprotein production in LDLR knockout mice F Saaoud, J Wang, S Iwanowycz, Y Wang, D Altomare, Y Shao, J Liu, PJ Blackshear, SM Lessner, EA Murphy, H Wang, X Yang, D Fan	Redox Biology	2020
Wnt signaling mediates oncogenic synergy between Akt and Dlx5 in T-cell lymphomagenesis by enhancing cholesterol synthesis Y Tan, E Sementino, Z Liu, KQ Cai, JR Testa	Scientific Reports	2020
The CCR4–NOT complex maintains liver homeostasis through mRNA deadenylation A Takahashi, T Suzuki, S Soeda, S Takaoka, S Kobori, T Yamaguchi, HM Mohamed, A Yanagiya, T Abe, M Shigeta, Y Furuta, K Kuba, T Yamamoto		2020
Sterol regulatory element-binding protein Sre1 regulates carotenogenesis in the red yeast Xanthophyllomyces dendrorhous M Gómez, S Campusano, MS Gutiérrez, D Sepúlveda, S Barahona, M Baeza, V Cifuentes, J Alcaíno	Journal of lipid research	2020
Metabolic regulation of hepatic PNPLA3 expression and severity of liver fibrosis in patients with NASH FV Bruschi, M Tardelli, M Herac, T Claudel, M Trauner	Liver International	2020
Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis C Chitraju, AW Fischer, RV Farese, TC Walther	Cell Reports	2020
Regulation of glial size by eicosapentaenoic acid through a novel Golgi apparatus mechanism A Zhang, Z Guan, K Ockerman, P Dong, J Guo, Z Wang, D Yan, R Daneman	PLoS Biology	2020
Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell E Mick, DV Titov, OS Skinner, R Sharma, AA Jourdain, VK Mootha	eLife	2020
Anabolic SIRT4 Exerts Retrograde Control over TORC1 Signaling by Glutamine Sparing in the Mitochondria E Shaw, M Talwadekar, Z Rashida, N Mohan, A Acharya, S Khatri, S Laxman, U Kolthur-Seetharam	Molecular and cellular biology	2020
NASH, Fibrosis and Hepatocellular Carcinoma: Lipid Synthesis and Glutamine/Acetate Signaling Y Sunami	International journal of molecular sciences	2020
Impaired lipid biosynthesis hinders anti-tumor efficacy of intratumoral iNKT cells S Fu, K He, C Tian, H Sun, C Zhu, S Bai, J Liu, Q Wu, D Xie, T Yue, Z Shen, Q Dai, X Yu, S Zhu, G Liu, R Zhou, S Duan, Z Tian, T Xu, H Wang, L Bai	Nature Communications	2020
Role of the Sterol Regulatory Element Binding Protein Pathway in Tumorigenesis T Jiang, G Zhang, Z Lou	Frontiers in Oncology	2020
A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism M Pradas-Juni, NR Hansmeier, JC Link, E Schmidt, BD Larsen, P Klemm, N Meola, H Topel, R Loureiro, I Dhaouadi, CA Kiefer, R Schwarzer, S Khani, M Oliverio, M Awazawa, P Frommolt, J Heeren, L Scheja, M Heine, C Dieterich, H Büning, L Yang, H Cao, DF Jesus, RN Kulkarni, B Zevnik, SE Tröder, U Knippschild, PA Edwards, RG Lee, M Yamamoto, I Ulitsky, E Fernandez-Rebollo, TQ de Aguiar Vallim, JW Kornfeld	Nature Communications	2020
Mechanistic Study of Triazole Based Aminodiol Derivatives in Leukemic Cells—Crosstalk between Mitochondrial Stress-Involved Apoptosis and Autophagy SH Chan, WJ Leu, SP Swain, JL Hsu, DR Hou, JH Guh	International journal of molecular sciences	2020
Lack of Augmenter of Liver Regeneration Disrupts Cholesterol Homeostasis of Liver in Mice by Inhibiting the AMPK Pathway X Wang, L Dong, Q Gai, W Ai, Y Wu, W Xiao, J Zhang, W An	Hepatology Communications	2020
Toll-Like Receptors Induce Signal-Specific Reprogramming of the Macrophage Lipidome WY Hsieh, QD Zhou, AG York, KJ Williams, PO Scumpia, EB Kronenberger, XP Hoi, B Su, X Chi, VL Bui, E Khialeeva, A Kaplan, YM Son, AS Divakaruni, J Sun, ST Smale, RA Flavell, SJ Bensinger	Cell Metabolism	2020
Molecular and Cellular Mechanisms of Electronegative Lipoproteins in Cardiovascular Diseases LY Ke, SH Law, VK Mishra, F Parveen, HC Chan, YH Lu, CS Chu	Biomedicines	2020
Naturally Occurring PCSK9 Inhibitors MP Adorni, F Zimetti, MG Lupo, M Ruscica, N Ferri	Nutrients	2020
Key role for lipids in cognitive symptoms of schizophrenia DA Maas, MB Martens, N Priovoulos, WA Zuure, JR Homberg, B Nait-Oumesmar, GJ Martens	Translational Psychiatry	2020
Innate immune signaling in Drosophila shifts anabolic lipid metabolism from triglyceride storage to phospholipid synthesis to support immune function BA Martínez, RG Hoyle, S Yeudall, ME Granade, TE Harris, JD Castle, N Leitinger, ML Bland, V Hietakangas	PLoS genetics	2020
Metabolic rivalry: circadian homeostasis and tumorigenesis K Kinouchi, P Sassone-Corsi	Nature Reviews Cancer	2020
Expression of SREBP2 and cholesterol metabolism related genes in TCGA glioma cohorts D Li, S Li, AZ Xue, LA Callahan, Y Liu	Medicine	2020
Involvement of overweight and lipid metabolism in the development of pulmonary hypertension under conditions of chronic intermittent hypoxia P Siques, J Brito, S Ordenes, E Pena	Pulmonary circulation	2020
A MicroRNA Linking Human Positive Selection and Metabolic Disorders L Wang, N Sinnott-Armstrong, A Wagschal, AR Wark, JP Camporez, RJ Perry, F Ji, Y Sohn, J Oh, S Wu, J Chery, BN Moud, A Saadat, SN Dankel, G Mellgren, DS Tallapragada, SM Strobel, MJ Lee, R Tewhey, PC Sabeti, A Schaefer, A Petri, S Kauppinen, RT Chung, A Soukas, J Avruch, SK Fried, H Hauner, RI Sadreyev, GI Shulman, M Claussnitzer, AM Näär	Cell	2020
The Pivotal Role of the Dysregulation of Cholesterol Homeostasis in Cancer: Implications for Therapeutic Targets EH Mok, TK Lee	Cancers	2020
Current Evidences and Future Perspectives for AMPK in the Regulation of Milk Production and Mammary Gland Biology Z Wu, M Tian, J Heng, J Chen, F Chen, W Guan, S Zhang	Frontiers in Cell and Developmental Biology	2020
Catalpol Attenuates Hepatic Steatosis by Regulating Lipid Metabolism via AMP-Activated Protein Kinase Activation X Tian, Q Ru, Q Xiong, R Wen, Y Chen	BioMed Research International	2020
SIRT6, a Mammalian Deacylase with Multitasking Abilities AR Chang, CM Ferrer, R Mostoslavsky	Physiological reviews	2020
Running Head: Heat Affects Cholesterol and Bile Acid Alterations in Cholesterol and Bile Acids Metabolism in Large White Pigs during Short-Term Heat Exposure W Fang, X Wen, Q Meng, L Liu, J Xie, H Zhang, N Everaert	Animals	2020
The Surprising Effect of Phenformin on Cutaneous Darkening and Characterization of Its Underlying Mechanism by a Forward Chemical Genetics Approach K Takano, A Hachiya, D Murase, A Kawasaki, H Uda, S Kasamatsu, Y Sugai, Y Takahashi, T Hase, A Ohuchi, T Suzuki	International journal of molecular sciences	2020
Bisacurone suppresses hepatic lipid accumulation through inhibiting lipogenesis and promoting lipolysis H Ashida, X Tian, T Kitakaze, Y Yamashita	Journal of Clinical Biochemistry and Nutrition	2020
The Role of Hypoxia-Inducible Factor 1α in the Regulation of Human Meibomian Gland Epithelial Cells Y Liu, J Wang, D Chen, WR Kam, DA Sullivan	Investigative ophthalmology & visual science	2020
ER-Resident Transcription Factor Nrf1 Regulates Proteasome Expression and Beyond J Hamazaki, S Murata	International journal of molecular sciences	2020
A newly discovered role of metabolic enzyme PCK1 as a protein kinase to promote cancer lipogenesis H Jiang, L Zhu, D Xu, Z Lu		2020
NAD(P)-dependent steroid dehydrogenase-like is involved in breast cancer cell growth and metastasis SH Yoon, HS Kim, RN Kim, SY Jung, BS Hong, EJ Kang, HB Lee, HG Moon, DY Noh, W Han	BMC Cancer	2020
Intestinal Population in Host with Metabolic Syndrome during Administration of Chitosan and Its Derivatives C Yan, C Zhang, X Cao, B Feng, X Li	Molecules (Basel, Switzerland)	2020
Lipidomics Issues on Human Positive ssRNA Virus Infection: An Update D Balgoma, L Gil-de-Gómez, O Montero	Metabolites	2020
Beyond the Mevalonate Pathway: Control of Post-Prenylation Processing by Mutant p53 CM Etichetti, EA Zalazar, N Cocordano, J Girardini	Frontiers in Oncology	2020
New Insights Into the Role of Phenotypic Plasticity and EMT in Driving Cancer Progression S Bhatia, P Wang, A Toh, EW Thompson	Frontiers in Molecular Biosciences	2020
Effect of dietary oils from various sources on carbohydrate and fat metabolism in mice A Altberg, R Hovav, N Chapnik, Z Madar	Food & Nutrition Research	2020
Mesencephalic astrocyte-derived neurotrophic factor ameliorates steatosis in HepG2 cells by regulating hepatic lipid metabolism M He, C Wang, XH Long, JJ Peng, DF Liu, GY Yang, MD Jensen, LL Zhang	World journal of gastroenterology : WJG	2020
Multi-layered epigenetic regulation of IRS2 expression in the liver of obese individuals with type 2 diabetes C Krause, C Geißler, H Tackenberg, AT Gammal, S Wolter, J Spranger, O Mann, H Lehnert, H Kirchner	Diabetologia	2020
Metabolic coessentiality mapping identifies C12orf49 as a regulator of SREBP processing and cholesterol metabolism EC Bayraktar, K La, K Karpman, G Unlu, C Ozerdem, DJ Ritter, H Alwaseem, H Molina, HH Hoffmann, A Millner, GE Atilla-Gokcumen, ER Gamazon, AR Rushing, EW Knapik, S Basu, K Birsoy	Nature metabolism	2020
Dietary Silk Peptide Prevents High-Fat Diet-Induced Obesity and Promotes Adipose Browning by Activating AMP-Activated Protein Kinase in Mice. Lee K, Jin H, Chei S, Lee JY, Oh HJ, Lee BY	Nutrients	2020
The Target of Rapamycin Signalling Pathway in Ageing and Lifespan Regulation Bjedov I, Rallis C	Genes & development	2020
Beneficial effects of Chinese herbs in the treatment of fatty liver diseases. Panyod S, Sheen LY	Journal of traditional and complementary medicine	2020
Phospholipase Cε Regulates Prostate Cancer Lipid Metabolism and Proliferation by Targeting AMP-Activated Protein Kinase (AMPK)/Sterol Regulatory Element-Binding Protein 1 (SREBP-1) Signaling Pathway. Zheng Y, Jin J, Gao Y, Luo C, Wu X, Liu J	Medical science monitor : international medical journal of experimental and clinical research	2020
Hypotriglyceridemic effects of brown seaweed consumption via regulation of bile acid excretion and hepatic lipogenesis in high fat diet-induced obese mice. Han AR, Kim JH, Kim E, Cui J, Chai IS, Zhang G, Lee Y	Nutrition Research and Practice	2020
Liver-specific microRNA-185 knockout promotes cholesterol dysregulation in mice. Chen C, Matye D, Wang Y, Li T	Liver Research	2020
Differential effects of Chinese high-fat dietary habits on lipid metabolism: mechanisms and health implications. Yan S, Zhou H, Liu S, Wang J, Zeng Y, Matias FB, Wen L	Lipids in Health and Disease	2020
The requirements for sterol regulatory element-binding protein (Srebp) and stimulatory protein 1 (Sp1)-binding elements in the transcriptional activation of two freshwater fish Channa striata and Danio rerio elovl5 elongase. Goh PT, Kuah MK, Chew YS, Teh HY, Shu-Chien AC	Fish Physiology and Biochemistry	2020
Metabolic Network Analysis Reveals Altered Bile Acid Synthesis and Metabolism in Alzheimer's Disease. Baloni P, Funk CC, Yan J, Yurkovich JT, Kueider-Paisley A, Nho K, Heinken A, Jia W, Mahmoudiandehkordi S, Louie G, Saykin AJ, Arnold M, Kastenmüller G, Griffiths WJ, Thiele I, Kaddurah-Daouk R, Price ND	Cell reports. Medicine	2020
A metastasis map of human cancer cell lines. Jin X, Demere Z, Nair K, Ali A, Ferraro GB, Natoli T, Deik A, Petronio L, Tang AA, Zhu C, Wang L, Rosenberg D, Mangena V, Roth J, Chung K, Jain RK, Clish CB, Vander Heiden MG, Golub TR	Nature	2020
Regulatory effect of diosgenin on lipogenic genes expression in high-fat diet-induced obesity in mice. Khateeb S, Albalawi A, Alkhedaide A	Saudi Journal of Biological Sciences	2020
Regulation of gene expression during the fasting-feeding cycle of the liver displays mouse strain specificity Chi Y, Youn DY, Xiaoli AM, Liu L, Pessin JB, Yang F, Pessin JE	The Journal of biological chemistry	2020
Supplemental Clostridium butyricum Modulates Lipid Metabolism Through Shaping Gut Microbiota and Bile Acid Profile of Aged Laying Hens Wang WW, Wang J, Zhang HJ, Wu SG, Qi GH	Frontiers in microbiology	2020
Maternal Malnutrition Affects Hepatic Metabolism through Decreased Hepatic Taurine Levels and Changes in HNF4A Methylation Du JE, You YA, Kwon EJ, Kim SM, Lee J, Han KH, Kim YJ	International journal of molecular sciences	2020
Oncogenic activation of PI3K-AKT-mTOR signaling suppresses ferroptosis via SREBP-mediated lipogenesis Yi J, Zhu J, Wu J, Thompson CB, Jiang X	Proceedings of the National Academy of Sciences	2020
Regulatory Roles of SREBF1 and SREBF2 in Lipid Metabolism and Deposition in Two Chinese Representative Fat-Tailed Sheep Breeds. Liang C, Qiao L, Han Y, Liu J, Zhang J, Liu W		2020
Effect of probiotics Lactobacillus paracasei GKS6, L. plantarum GKM3, and L. rhamnosus GKLC1 on alleviating alcohol-induced alcoholic liver disease in a mouse model. Tsai YS, Lin SW, Chen YL, Chen CC	Nutrition Research and Practice	2020
Nicotinamide Phosphoribosyltransferase Knockdown Leads to Lipid Accumulation in HepG2 Cells through The SIRT1-AMPK Pathway. Ilbeigi D, Nourbakhsh M, Pasalar P, Meshkani R, Shokri Afra H, Panahi GH, Borji M, Sharifi R		2020
The cellular function of SCAP in metabolic signaling Lee SH, Lee JH, Im SS	Experimental & molecular medicine	2020
Maternal Dietary Exposure to Low-Dose Bisphenol A Affects Metabolic and Signaling Pathways in the Brain of Rat Fetuses Tonini C, Segatto M, Gagliardi S, Bertoli S, Leone A, Barberio L, Mandalà M, Pallottini V	Nutrients	2020
Fatty Acid Composition and Regulatory Gene Expression in Late-Term Embryos of ACRB and COBB Broilers Su S, Wang Y, Chen C, Suh M, Azain M, Kim WK	Frontiers in Veterinary Science	2020
Imperatorin and β‐sitosterol have synergistic activities in alleviating collagen‐induced arthritis Guo Q, Li L, Zheng K, Zheng G, Shu H, Shi Y, Lu C, Shu J, Guan D, Lu A, He X	Journal of leukocyte biology	2020
An Atomic-Level Perspective of HMG-CoA-Reductase: The Target Enzyme to Treat Hypercholesterolemia Gesto DS, Pereira CM, Cerqueira NM, Sousa SF	Molecules (Basel, Switzerland)	2020
PCSK9: A Key Target for the Treatment of Cardiovascular Disease (CVD) Sobati S, Shakouri A, Edalati M, Mohammadnejad D, Parvan R, Masoumi J, Abdolalizadeh J	Advanced pharmaceutical bulletin	2020
Dietary betaine improves egg-laying rate in hens through hypomethylation and glucocorticoid receptor–mediated activation of hepatic lipogenesis-related genes Omer NA, Hu Y, Idriss AA, Abobaker H, Hou Z, Yang S, Ma W, Zhao R	Poultry science	2020
Circulating expression of Hsa_circRNA_102893 contributes to early gestational diabetes mellitus detection Yang H, Ye W, Chen R, Zeng F, Long Y, Zhang X, Ma J, Gan Q, Rehemutula R, Zhu C	Scientific Reports	2020
Arachidonic acid induces ER stress and apoptosis in HT-29 human colon cancer cells Bae S, Kim MK, Kim HS, Moon YA	Animal Cells and Systems	2020
Sijunzi, Lizhong, and Fuzilizhong Decoction Alleviate Nonalcoholic Fatty Liver Disease through Activation of PPAR Pathway Yang J, Tao D, Ma W, Liu S, Liao Y, Shu L, Zhang S, Li C, Du N, Shi Z	Evidence-based complementary and alternative medicine : eCAM	2020
Nostoc sphaeroids Kütz ameliorates hyperlipidemia and maintains the intestinal barrier and gut microbiota composition of high-fat diet mice. Wei F, Liu Y, Bi C, Chen S, Wang Y, Zhang B	Food Science & Nutrition	2020
Eukaryotic response to hypothermia in relation to integrated stress responses. Adjirackor NA, Harvey KE, Harvey SC	Cell Stress & Chaperones	2020
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism. Aregger M, Lawson KA, Billmann M, Costanzo M, Tong AHY, Chan K, Rahman M, Brown KR, Ross C, Usaj M, Nedyalkova L, Sizova O, Habsid A, Pawling J, Lin ZY, Abdouni H, Wong CJ, Weiss A, Mero P, Dennis JW, Gingras AC, Myers CL, Andrews BJ, Boone C, Moffat J	Nature metabolism	2020
Novel Genomic Regions Associated with Intramuscular Fatty Acid Composition in Rabbits. Laghouaouta H, Sosa-Madrid BS, Zubiri-Gaitán A, Hernández P, Blasco A		2020
Inhibition of SREBP Improves Cardiac Lipidopathy, Improves Endoplasmic Reticulum Stress, and Modulates Chronic Chagas Cardiomyopathy Ayyappan JP, Lizardo K, Wang S, Yurkow E, Nagajyothi JF	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease	2020
ssRNA Virus and Host Lipid Rearrangements: Is There a Role for Lipid Droplets in SARS-CoV-2 Infection? Pagliari F, Marafioti MG, Genard G, Candeloro P, Viglietto G, Seco J, Tirinato L	Frontiers in Molecular Biosciences	2020
Identification of a degradation signal at the carboxy terminus of SREBP2: A new role for this domain in cholesterol homeostasis Kober DL, Xu S, Li S, Bajaj B, Liang G, Rosenbaum DM, Radhakrishnan A	Proceedings of the National Academy of Sciences	2020
Type 1 interferon-dependent repression of NLRC4 and iPLA2 licenses down-regulation of Salmonella flagellin inside macrophages Akhade AS, Atif SM, Lakshmi BS, Dikshit N, Hughes KT, Qadri A, Subramanian N	Proceedings of the National Academy of Sciences	2020
Omega-3 polyunsaturated fatty acids: anti-inflammatory and anti-hypertriglyceridemia mechanisms in cardiovascular disease. Shibabaw T	Molecular and Cellular Biochemistry	2020
Anabolic androgenic steroids exert a selective remodeling of the plasma lipidome that mirrors the decrease of the de novo lipogenesis in the liver Balgoma D, Zelleroth S, Grönbladh A, Hallberg M, Pettersson C, Hedeland M	Metabolomics : Official journal of the Metabolomic Society	2020
USP7 mediates pathological hepatic de novo lipogenesis through promoting stabilization and transcription of ZNF638 Ni W, Lin S, Bian S, Zheng W, Qu L, Fan Y, Lu C, Xiao M, Zhou P	Cell Death and Disease	2020
SREBP-regulated adipocyte lipogenesis is dependent on substrate availability and redox modulation of mTORC1 Clair Crewe, Yi Zhu, Vivian A. Paschoal, Nolwenn Joffin, Alexandra L. Ghaben, Ruth Gordillo, Da Young Oh, Guosheng Liang, Jay D. Horton, Philipp E. Scherer	JCI Insight	2019
Renal Fibrosis: Mechanisms and Therapies BC Liu, HY Lan, LL Lv		2019
RA-XII Suppresses the Development and Growth of Liver Cancer by Inhibition of Lipogenesis via SCAP-dependent SREBP Supression D Guo, Y Wang, J Wang, L Song, Z Wang, B Mao, N Tan	Molecules (Basel, Switzerland)	2019
Regulation of Hepatic Metabolism, Recent Advances, and Future Perspectives K Sharabi, CD Tavares, P Puigserver	Current Diabetes Reports	2019
Novel role of NLRP3-inflammasome in regulation of lipogenesis in fasting-induced hepatic steatosis B Liu, X Mao, D Huang, F Li, N Dong	Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy	2019
Capsaicin Targets Lipogenesis in HepG2 Cells Through AMPK Activation, AKT Inhibition and PPARs Regulation A Bort, B Sánchez, P Mateos-Gómez, I Díaz-Laviada, N Rodríguez-Henche	International journal of molecular sciences	2019
Decoding inflammation, its causes, genomic responses, and emerging countermeasures J Hawiger, J Zienkiewicz	Scandinavian Journal of Immunology	2019
Carcinoembryonic Cell Adhesion-Related Molecule 2 Regulates Insulin Secretion and Energy Balance E Salaheldeen, A Jaume, SM Najjar	International journal of molecular sciences	2019
Identification of a novel function of hepatic long-chain acyl-CoA synthetase-1 (ACSL1) in bile acid synthesis and its regulation by bile acid-activated farnesoid X receptor AB Singh, B Dong, Y Xu, Y Zhang, J Liu	Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids	2019
A chemical biology screen identifies a vulnerability of neuroendocrine cancer cells to SQLE inhibition CE Mahoney, D Pirman, V Chubukov, T Sleger, S Hayes, ZP Fan, EL Allen, Y Chen, L Huang, M Liu, Y Zhang, G McDonald, R Narayanaswamy, S Choe, Y Chen, S Gross, G Cianchetta, AK Padyana, S Murray, W Liu, KM Marks, J Murtie, M Dorsch, S Jin, N Nagaraja, SA Biller, T Roddy, J Popovici-Muller, GA Smolen	Nature Communications	2019
The Potential of Isoprenoids in Adjuvant Cancer Therapy to Reduce Adverse Effects of Statins H Mo, R Jeter, A Bachmann, ST Yount, CL Shen, H Yeganehjoo	Frontiers in pharmacology	2019
Cholesterol Metabolism: A Potential Therapeutic Target in Glioblastoma F Ahmad, Q Sun, D Patel, J Stommel	Cancers	2019
Hyperinsulinemia drives hepatic insulin resistance in male mice with liver-specific Ceacam1 deletion independently of lipolysis HE Ghadieh, L Russo, HT Muturi, SS Ghanem, IH Manaserh, HL Noh, S Suk, JK Kim, JW Hill, SM Najjar	Metabolism	2019
Chewing the Fat: The Conserved Ability of DNA Viruses to Hijack Cellular Lipid Metabolism P Lange, M Lagunoff, V Tarakanova	Viruses	2019
Mg-supplementation attenuated lipogenic and oxidative/nitrosative gene expression caused by Combination Antiretroviral Therapy (cART) in HIV-1-transgenic rats L ElZohary, WB Weglicki, JJ Chmielinska, JH Kramer, IT Mak, M Bader	PloS one	2019
ENOblock inhibits the pathology of diet-induced obesity H Cho, JH Lee, JI Um, S Kim, Y Kim, WH Kim, YS Kim, HS Pagire, JH Ahn, Y Ahn, YT Chang, DW Jung, DR Williams	Scientific Reports	2019
Non-antibody Approaches to Proprotein Convertase Subtilisin Kexin 9 Inhibition: siRNA, Antisense Oligonucleotides, Adnectins, Vaccination, and New Attempts at Small-Molecule Inhibitors Based on New Discoveries T Nishikido, KK Ray	Frontiers in Cardiovascular Medicine	2019
Hepatic Sdf2l1 controls feeding-induced ER stress and regulates metabolism T Sasako, M Ohsugi, N Kubota, S Itoh, Y Okazaki, A Terai, T Kubota, S Yamashita, K Nakatsukasa, T Kamura, K Iwayama, K Tokuyama, H Kiyonari, Y Furuta, J Shibahara, M Fukayama, K Enooku, K Okushin, T Tsutsumi, R Tateishi, K Tobe, H Asahara, K Koike, T Kadowaki, K Ueki	Nature Communications	2019
A functional interaction between Hippo-YAP signalling and SREBPs mediates hepatic steatosis in diabetic mice Z Shu, Y Gao, G Zhang, Y Zhou, J Cao, D Wan, X Zhu, W Xiong	Journal of Cellular and Molecular Medicine	2019
It takes a village: channeling fatty acid metabolism and triacylglycerol formation via protein interactomes RA Coleman	Journal of lipid research	2019
How Viral and Intracellular Bacterial Pathogens Reprogram the Metabolism of Host Cells to Allow Their Intracellular Replication W Eisenreich, T Rudel, J Heesemann, W Goebel	Frontiers in Cellular and Infection Microbiology	2019
Effects of feeding ethanol on growth performances, carcass characteristics, and lipid metabolism of finishing Korean cattle (Hanwoo) steers CB Choi, H Kwon, KH Hwang, HJ Lee, JY Kim	Asian-Australasian Journal of Animal Sciences	2019
Sterol regulatory element binding protein 1 couples mechanical cues and lipid metabolism R Bertolio, F Napoletano, M Mano, S Maurer-Stroh, M Fantuz, A Zannini, S Bicciato, G Sorrentino, GD Sal	Nature Communications	2019
Multi-dimensional Transcriptional Remodeling by Physiological Insulin In Vivo TM Batista, R Garcia-Martin, W Cai, M Konishi, BT ONeill, M Sakaguchi, JH Kim, DY Jung, JK Kim, CR Kahn	Cell Reports	2019
Cideb controls sterol‐regulated ER export of SREBP/SCAP by promoting cargo loading at ER exit sites L Su, L Zhou, FJ Chen, H Wang, H Qian, Y Sheng, Y Zhu, H Yu, X Gong, L Cai, X Yang, L Xu, TJ Zhao, JZ Li, XW Chen, P Li	The EMBO Journal	2019
Accumulation of PNPLA3 on lipid droplets is the basis of associated hepatic steatosis S BasuRay, Y Wang, E Smagris, JC Cohen, HH Hobbs	Proceedings of the National Academy of Sciences	2019
Dynamic repression by BCL6 controls the genome-wide liver response to fasting and steatosis MA Sommars, K Ramachandran, MD Senagolage, CR Futtner, DM Germain, AL Allred, Y Omura, IR Bederman, GD Barish	eLife	2019
Cholesterol enrichment in liver mitochondria impairs oxidative phosphorylation and disrupts the assembly of respiratory supercomplexes E Solsona-Vilarrasa, R Fucho, S Torres, S Nuñez, N Nuño-Lámbarri, C Enrich, C García-Ruiz, JC Fernández-Checa	Redox Biology	2019
Cholesterol Trafficking: An Emerging Therapeutic Target for Angiogenesis and Cancer J Lyu, EJ Yang, JS Shim	Cells	2019
Roux-en-Y Gastric Bypass Improves Metabolic Conditions in Association with Increased Serum Bile Acids Level and Hepatic Farnesoid X Receptor Expression in a T2DM Rat Model Y Yan, Y Sha, X Huang, W Yuan, F Wu, J Hong, S Fang, B Huang, C Hu, B Wang, X Zhang	Obesity Surgery	2019
Proprotein convertase subtilisin/kexin type 9 and lipid metabolism: S Spolitu, W Dai, JA Zadroga, L Ozcan	Current Opinion in Lipidology	2019
Arazyme Suppresses Hepatic Steatosis and Steatohepatitis in Diet-Induced Non-Alcoholic Fatty Liver Disease-Like Mouse Model H Li, W Yoo, HM Park, SY Lim, DH Shin, S Kim, HY Park, TS Jeong	International journal of molecular sciences	2019
Feature Article: Transplantation of neuregulin 4-overexpressing adipose-derived mesenchymal stem cells ameliorates insulin resistance by attenuating hepatic steatosis W Wang, Y Zhang, C Yang, Y Wang, J Shen, M Shi, B Wang	Experimental biology and medicine (Maywood, N.J.)	2019
Caffeine-free hawk tea lowers cholesterol by reducing free cholesterol uptake and the production of very-low-density lipoprotein J Feng, J Yang, Y Chang, L Qiao, H Dang, K Luo, H Guo, Y An, C Ma, H Shao, J Tian, Y Yuan, L Xie, W Xing, J Cheng		2019
A lipid-free and insulin-supplemented medium supports De Novo fatty acid synthesis gene activation in melanoma cells S Wu, AM Näär, JT Nickels	PloS one	2019
SREBP1 drives Keratin-80-dependent cytoskeletal changes and invasive behavior in endocrine-resistant ERα breast cancer Y Perone, AJ Farrugia, AR Meira, B Győrffy, C Ion, A Uggetti, A Chronopoulos, P Marrazzo, M Faronato, S Shousha, C Davies, JH Steel, N Patel, A del Rio Hernandez, C Coombes, G Pruneri, A Lim, F Calvo, L Magnani	Nature Communications	2019
Tropomyosin-receptor kinase fused gene (TFG) regulates lipid production in human sebocytes SR Choi, YL Hwang, SJ Kim, KC Sohn, CW Choi, KD Park, Y Lee, YJ Seo, JH Lee, SP Hong, SJ Seo, SJ Kim, CD Kim	Scientific Reports	2019
Combined effects of ambient particulate matter exposure and a high-fat diet on oxidative stress and steatohepatitis in mice S Ding, C Yuan, B Si, M Wang, S Da, L Bai, W Wu, Q Sun	PloS one	2019
Enhanced early-life nutrition upregulates cholesterol biosynthetic gene expression and Sertoli cell maturation in testes of pre-pubertal Holstein bulls C Johnson, A Dance, I Kovalchuk, J Kastelic, J Thundathil	Scientific Reports	2019
Influences of sterol regulatory element binding protein-1c silencing on glucose production in HepG2 cells treated with free fatty acid XP Bai, F Dong, GH Yang, L Zhang	Lipids in Health and Disease	2019
An actionable sterol-regulated feedback loop modulates statin sensitivity in prostate cancer J Longo, PJ Mullen, R Yu, JE van Leeuwen, M Masoomian, DT Woon, Y Wang, EX Chen, RJ Hamilton, JM Sweet, TH van der Kwast, NE Fleshner, LZ Penn	Molecular Metabolism	2019
Yarrow supercritical extract exerts antitumoral properties by targeting lipid metabolism in pancreatic cancer L Mouhid, MG de Cedrón, E García-Carrascosa, G Reglero, T Fornari, AR de Molina, OA Sukocheva	PloS one	2019
Paeonol Ameliorates Glucose and Lipid Metabolism in Experimental Diabetes by Activating Akt F Xu, H Xiao, R Liu, Y Yang, M Zhang, L Chen, Z Chen, P Liu, H Huang	Frontiers in pharmacology	2019
Statins and Inflammation: New Therapeutic Opportunities in Psychiatry SW Kim, HJ Kang, M Jhon, JW Kim, JY Lee, AJ Walker, B Agustini, JM Kim, M Berk	Frontiers in Psychiatry	2019
FTY720/fingolimod decreases hepatic steatosis and expression of fatty acid synthase in diet-induced nonalcoholic fatty liver disease in mice TD Rohrbach, A Asgharpour, MA Maczis, D Montefusco, LA Cowart, P Bedossa, AJ Sanyal, S Spiegel	Journal of lipid research	2019
SREBP1-dependent de novo fatty acid synthesis gene expression is elevated in malignant melanoma and represents a cellular survival trait S Wu, AM Näär	Scientific Reports	2019
Gene expression and DNA methylation as mechanisms of disturbed metabolism in offspring after exposure to a prenatal HF diet SH Rouschop, T Karl, A Risch, PA van Ewijk, VB Schrauwen-Hinderling, A Opperhuizen, FJ van Schooten, RW Godschalk	Journal of lipid research	2019
Ambient particulate matter attenuates Sirtuin1 and augments SREBP1-PIR axis to induce human pulmonary fibroblast inflammation: molecular mechanism of microenvironment associated with COPD CP Tien, CH Chen, WY Lin, CS Liu, KJ Liu, M Hsiao, YC Chang, SC Hung	Aging	2019
Tissue-specific changes in Srebf1 and Srebf2 expression and DNA methylation with perinatal phthalate exposure L Moody, D Hernández-Saavedra, DG Kougias, H Chen, JM Juraska, YX Pan, M Skinner	Environmental Epigenetics	2019
Comparison of liver transcriptome from high- and low-intramuscular fat Chaohu ducks provided additional candidate genes for lipid selection K Ge, X Chen, J Kuang, L Yang, Z Geng	3 Biotech	2019
RNA-Sequencing Analysis of Paternal Low-Protein Diet-Induced Gene Expression Change in Mouse Offspring Adipocytes NH Ly, T Maekawa, K Yoshida, Y Liu, M Muratani, S Ishii	G3: Genes\|Genomes\|Genetics	2019
Control of LDL Uptake in Human Cells by Targeting the LDLR Regulatory Long Non-coding RNA BM450697 RM Ray, AH Hansen, S Slott, M Taskova, K Astakhova, KV Morris	Molecular Therapy — Nucleic Acids	2019
Ursodeoxycholic Acid Alters Bile Acid and Fatty Acid Profiles in a Mouse Model of Diet-Induced Obesity Y Zhang, X Zheng, F Huang, A Zhao, K Ge, Q Zhao, W Jia	Frontiers in pharmacology	2019
The Cytokine TNF Promotes Transcription Factor SREBP Activity and Binding to Inflammatory Genes to Activate Macrophages and Limit Tissue Repair A Kusnadi, SH Park, R Yuan, T Pannellini, E Giannopoulou, D Oliver, T Lu, KH Park-Min, LB Ivashkiv	Immunity	2019
GRP94 Is Involved in the Lipid Phenotype of Brain Metastatic Cells N Santana-Codina, A Marcé-Grau, L Muixí, C Nieva, M Marro, D Sebastián, JP Muñoz, A Zorzano, A Sierra	International journal of molecular sciences	2019
The Administration of Chitosan-Tripolyphosphate-DNA Nanoparticles to Express Exogenous SREBP1a Enhances Conversion of Dietary Carbohydrates into Lipids in the Liver of Sparus aurata JI Silva-Marrero, J Villasante, A Rashidpour, M Palma, A Fàbregas, MP Almajano, I Viegas, JG Jones, M Miñarro, JR Ticó, IV Baanante, I Metón	Biomolecules	2019
Transforming Growth Factor β Acts as a Regulatory Molecule for Lipogenic Pathways among Hepatitis C Virus Genotype-Specific Infections T Patra, R Sasaki, K Meyer, RB Ray, R Ray, JH Ou	Journal of virology	2019
SREBF1c and SREBF2 gene polymorphisms are associated with acute coronary syndrome and blood lipid levels in Mexican population G Vargas-Alarcon, H Gonzalez-Pacheco, O Perez-Mendez, R Posadas-Sanchez, G Cardoso-Saldaña, J Ramirez-Bello, G Escobedo, B Nieto-Lima, JM Fragoso, AR de Molina	PloS one	2019
Effect of divergence in residual feed intake on expression of lipid metabolism-related genes in the liver of meat-type ducks1 S Jin, L Yang, X Fan, M Wu, Y Xu, X Chen, Z Lin, Z Geng	Journal of animal science	2019
Circadian lipid synthesis in brown fat maintains murine body temperature during chronic cold M Adlanmerini, BJ Carpenter, JR Remsberg, Y Aubert, LC Peed, HJ Richter, MA Lazar	Proceedings of the National Academy of Sciences	2019
Novel Lipid Long Intervening Noncoding RNA, Oligodendrocyte Maturation‐Associated Long Intergenic Noncoding RNA, Regulates the Liver Steatosis Gene Stearoyl‐Coenzyme A Desaturase As an Enhancer RNA JN Benhammou, A Ko, M Alvarez, MU Kaikkonen, C Rankin, KM Garske, D Padua, Y Bhagat, D Kaminska, V Kärjä, J Pihlajamäki, JR Pisegna, P Pajukanta	Hepatology Communications	2019
Industrial Trans Fatty Acids Stimulate SREBP2‐Mediated Cholesterogenesis and Promote Non‐Alcoholic Fatty Liver Disease AB Oteng, A Loregger, M Weeghel, N Zelcer, S Kersten	Molecular Nutrition & Food Research	2019
Function and Transcriptional Regulation of Bovine TORC2 Gene in Adipocytes: Roles of C/EBP, XBP1, INSM1 and ZNF263 Khan, Raza, Junjvlieke, Xiaoyu, Garcia, Elnour, Hongbao, Linsen	International journal of molecular sciences	2019
PAR2 controls cholesterol homeostasis and lipid metabolism in nonalcoholic fatty liver disease R Rana, AM Shearer, EK Fletcher, N Nguyen, S Guha, DH Cox, M Abdelmalek, Y Wang, JD Baleja, L Covic, A Kuliopulos	Molecular Metabolism	2019
Hepatic Transcriptomics Reveals that Lipogenesis Is a Key Signaling Pathway in Isocitrate Dehydrogenase 2 Deficient Mice JH Pan, J Tang, MC Redding, KE Beane, CL Conner, YJ Cho, J Zhao, JH Kim, BC Kong, JH Lee, JK Kim	Genes & development	2019
Calorie-Restriction-Induced Insulin Sensitivity Is Mediated by Adipose mTORC2 and Not Required for Lifespan Extension D Yu, JL Tomasiewicz, SE Yang, BR Miller, MH Wakai, DS Sherman, NE Cummings, EL Baar, JA Brinkman, FA Syed, DW Lamming	Cell Reports	2019
Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP ‐1 Y Zhang, C Li, C Hu, Q Wu, Y Cai, S Xing, H Lu, L Wang, D Huang, L Sun, T Li, X He, X Zhong, J Wang, P Gao, ZJ Smith, W Jia, H Zhang	EMBO reports	2019
Hydrogen sulfide inhibits PCSK9 expression through the PI3K/Akt‑SREBP‑2 signaling pathway to influence lipid metabolism in HepG2 cells J Xiao, XQ Bai, L Liao, M Zhou, J Peng, Q Xiang, Z Ren, HY Wen, ZS Jiang, ZH Tang, MM Wang, LS Liu	International journal of molecular medicine	2019
Effects of Paramylon Extracted from Euglena gracilis EOD-1 on Parameters Related to Metabolic Syndrome in Diet-Induced Obese Mice S Aoe, C Yamanaka, K Koketsu, M Nishioka, N Onaka, N Nishida, M Takahashi	Nutrients	2019
ASPP2 inhibits tumor growth by repressing the mevalonate pathway in hepatocellular carcinoma B Liang, R Chen, S Song, H Wang, G Sun, H Yang, W Jing, X Zhou, Z Fu, G Huang, J Zhao	Cell Death and Disease	2019
Hepatic triglyceride accumulation via endoplasmic reticulum stress-induced SREBP-1 activation is regulated by ceramide synthases YR Kim, EJ Lee, KO Shin, MH Kim, Y Pewzner-Jung, YM Lee, JW Park, AH Futerman, WJ Park	Experimental & molecular medicine	2019
Isorhamnetin Alleviates Steatosis and Fibrosis in Mice with Nonalcoholic Steatohepatitis M Ganbold, Y Owada, Y Ozawa, Y Shimamoto, F Ferdousi, K Tominaga, YW Zheng, N Ohkohchi, H Isoda	Scientific Reports	2019
The unfolded protein response and hepatic lipid metabolism in non alcoholic fatty liver disease MJ Song, H Malhi	Pharmacology & Therapeutics	2019
The Potential of the FSP1cre-Pparb/d−/− Mouse Model for Studying Juvenile NAFLD Chen, Zhuang, Sng, Tan, Wahli	International journal of molecular sciences	2019
GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis H Yu, A Rimbert, AE Palmer, T Toyohara, Y Xia, F Xia, LM Ferreira, Z Chen, T Chen, N Loaiza, NB Horwitz, MC Kacergis, L Zhao, AA Soukas, JA Kuivenhoven, S Kathiresan, CA Cowan	Cell	2019
Corticosterone-mediated physiological stress modulates hepatic lipid metabolism, metabolite profiles, and systemic responses in chickens SJ Zaytsoff, CL Brown, T Montina, GA Metz, DW Abbott, RR Uwiera, GD Inglis	Scientific Reports	2019
PRMT5 in gene regulation and hematologic malignancies F Zhu, L Rui	Genes & Diseases	2019
Heat Shock Factor 1 Is a Direct Antagonist of AMP-Activated Protein Kinase KH Su, S Dai, Z Tang, M Xu, C Dai	Molecular Cell	2019
Targeting extracellular nutrient dependencies of cancer cells J Garcia-Bermudez, RT Williams, R Guarecuco, K Birsoy	Molecular Metabolism	2019
Uncarboxylated osteocalcin ameliorates hepatic glucose and lipid metabolism in KKAy mice via activating insulin signaling pathway X Zhang, Y Wang, L Ma, Z Liu, F Ye, J Yang	Acta Pharmacologica Sinica	2019
Investigation of the association between obesity and insulin-induced gene 1 polymorphism at 7q36.3 region in Uygur population in Xinjiang, China J Tao, M Abudoukelimu, X Shen, J Liu, F Wang, J Yuan, PP Gu, W Zhu, X Zhang, Z Wang, Y Ma, G Li	Bioscience Reports	2019
WDR76 mediates obesity and hepatic steatosis via HRas destabilization JC Park, WJ Jeong, SH Seo, KY Choi	Scientific Reports	2019
Gene expressions of de novo hepatic lipogenesis in feline hepatic lipidosis C Valtolina, JH Robben, ME van Wolferen, HS Kruitwagen, RJ Corbee, RP Favier, LC Penning	Journal of Feline Medicine & Surgery	2019
Even Cancer Cells Watch Their Cholesterol! R Riscal, N Skuli, MC Simon	Molecular Cell	2019
The MYC Oncogene Cooperates with Sterol-Regulated Element-Binding Protein to Regulate Lipogenesis Essential for Neoplastic Growth AM Gouw, K Margulis, NS Liu, SJ Raman, A Mancuso, GG Toal, L Tong, A Mosley, AL Hsieh, DK Sullivan, ZE Stine, BJ Altman, A Schulze, CV Dang, RN Zare, DW Felsher	Cell Metabolism	2019
Yarrow Supercritical Extract Ameliorates the Metabolic Stress in a Model of Obesity Induced by High-Fat Diet L Mouhid, MG de Cedrón, A Quijada-Freire, PJ Fernández-Marcos, G Reglero, T Fornari, AR de Molina	Nutrients	2019
Proteolytic Control of Lipid Metabolism PN Sam, E Avery, SM Claypool	ACS chemical biology	2019
High Energy Intake Induced Overexpression of Transcription Factors and Its Regulatory Genes Involved in Acceleration of Hepatic Lipogenesis: A Rat Model for Type 2 Diabetes SP Khadke, AA Kuvalekar, AM Harsulkar, N Mantri	Biomedicines	2019
Semen Cuscutae Administration Improves Hepatic Lipid Metabolism and Adiposity in High Fat Diet-Induced Obese Mice J Moon, MJ Ha, MJ Shin, OY Kim, EH Yoo, J Song, JH Chung	Nutrients	2019
Enhanced acyl-CoA:cholesterol acyltransferase activity increases cholesterol levels on the lipid droplet surface and impairs adipocyte function Y Xu, X Du, N Turner, AJ Brown, H Yang	The Journal of biological chemistry	2019
Distinct metabolic adaptation of liver circadian pathways to acute and chronic patterns of alcohol intake J Gaucher, K Kinouchi, N Ceglia, E Montellier, S Peleg, CM Greco, A Schmidt, I Forne, S Masri, P Baldi, A Imhof, P Sassone-Corsi	Proceedings of the National Academy of Sciences	2019
Angiotensinogen in hepatocytes contributes to Western diet-induced liver steatosis XR Tao, JB Rong, HS Lu, A Daugherty, P Shi, CL Ke, ZC Zhang, YC Xu, JA Wang	Journal of lipid research	2019
The PI3K–AKT network at the interface of oncogenic signalling and cancer metabolism G Hoxhaj, BD Manning	Nature Reviews Cancer	2019
Asiatic acid prevents renal fibrosis in UUO rats via promoting the production of 15d-PGJ2, an endogenous ligand of PPAR-γ Z Zhang, J He, Y Zhao, H Chen, N Tan	Acta Pharmacologica Sinica	2019
The Use of High-Throughput Transcriptomics to Identify Pathways with Therapeutic Significance in Podocytes AK Solanki, P Srivastava, B Rahman, JH Lipschutz, D Nihalani, E Arif	International journal of molecular sciences	2019
Lung cancer cells survive epidermal growth factor receptor tyrosine kinase inhibitor exposure through upregulation of cholesterol synthesis MC Howell, R Green, R Khalil, E Foran, W Quarni, R Nair, S Stevens, A Grinchuk, A Hanna, S Mohapatra, S Mohapatra	FASEB bioAdvances	2019
Molecular logic of mTORC1 signalling as a metabolic rheostat A Valvezan, B Manning	Nature metabolism	2019
Metabolic influence on macrophage polarization and pathogenesis Thapa B, Lee K	BMB Reports	2019
A Regulatory Role of Apoptosis Antagonizing Transcription Factor in the Pathogenesis of Nonalcoholic Fatty Liver Disease and Hepatocellular Carcinoma. Kumar DP, Santhekadur PK, Seneshaw M, Mirshahi F, Uram-Tuculescu C, Sanyal AJ	Hepatology	2019
Lysosomal acid lipase deficiency - early diagnosis is the key. Strebinger G, Müller E, Feldman A, Aigner E	Hepatic medicine : evidence and research	2019
Deep transcriptome analysis using RNA-Seq suggests novel insights into molecular aspects of fat-tail metabolism in sheep. Bakhtiarizadeh MR, Salehi A, Alamouti AA, Abdollahi-Arpanahi R, Salami SA	Scientific Reports	2019
Effects of Gelidium elegans on Weight and Fat Mass Reduction and Obesity Biomarkers in Overweight or Obese Adults: A Randomized Double-Blinded Study. Kim CO, Kim YN, Lee DC	Nutrients	2019
Iron overload reduces synthesis and elimination of bile acids in rat liver. Prasnicka A, Lastuvkova H, Alaei Faradonbeh F, Cermanova J, Hroch M, Mokry J, Dolezelova E, Pavek P, Zizalova K, Vitek L, Nachtigal P, Micuda S	Scientific Reports	2019
Long-term luseogliflozin therapy improves histological activity of non-alcoholic steatohepatitis accompanied by type 2 diabetes mellitus. Fujimori N, Tanaka N, Kimura T, Sano K, Horiuchi A, Kato N, Takahashi Y, Kuribayashi N, Sugiura A, Yamazaki T, Joshita S, Umemura T, Matsumoto A, Tanaka E	Clinical Journal of Gastroenterology	2019
Impact of psychiatric comorbidity on the severity, short-term functional outcome, and psychiatric complications after acute stroke. Hoyer C, Schmidt HL, Kranaster L, Alonso A	Neuropsychiatric Disease and Treatment	2019
Teriparatide Improves Bone and Lipid Metabolism in a Male Rat Model of Type 2 Diabetes Mellitus. Nomura S, Kitami A, Takao-Kawabata R, Takakura A, Nakatsugawa M, Kono R, Maeno A, Tokuda A, Isogai Y, Ishizuya T, Utsunomiya H, Nakamura M	Endocrinology	2019
Black Raspberry (Rubus coreanus Miquel) Promotes Browning of Preadipocytes and Inguinal White Adipose Tissue in Cold-Induced Mice. Park WY, Choe SK, Park J, Um JY	Nutrients	2019
Protection from Endotoxin Shock by Selective Targeting of Proinflammatory Signaling to the Nucleus Mediated by Importin Alpha 5. Liu Y, Veach RA, Zienkiewicz J, Boyd KL, Smith TE, Xu ZQ, Wylezinski LS, Hawiger J	ImmunoHorizons	2019
Inhibition of HSP90β Improves Lipid Disorders by Promoting Mature SREBPs Degradation via the Ubiquitin-proteasome System. Zheng ZG, Zhang X, Liu XX, Jin XX, Dai L, Cheng HM, Jing D, Thu PM, Zhang M, Li H, Zhu J, Liu C, Xue B, Li Y, Chen L, Peng C, Zhu W, Wang L, Liu J, Li HJ, Li P, Xu X	Theranostics	2019
Anti-Metabolic Syndrome Effects of Fucoidan from Fucus vesiculosus via Reactive Oxygen Species-Mediated Regulation of JNK, Akt, and AMPK Signaling. Wang X, Shan X, Dun Y, Cai C, Hao J, Li G, Cui K, Yu G	Molecules (Basel, Switzerland)	2019
Integrated Analys of High-Fat Challenge-Induced Changes in Blood Cell Whole-Genome Gene Expression. Matualatupauw JC, O'Grada C, Hughes MF, Roche HM, Afman LA, Bouwman J	Molecular Nutrition & Food Research	2019
Ostreolysin A and anthrolysin O use different mechanisms to control movement of cholesterol from the plasma membrane to the endoplasmic reticulum. Johnson KA, Endapally S, Vazquez DC, Infante RE, Radhakrishnan A	The Journal of biological chemistry	2019
Penfluridol as a Candidate of Drug Repurposing for Anticancer Agent. Tuan NM, Lee CH	Molecules (Basel, Switzerland)	2019
Effects of Dietary Supplementation of Alpha-Ketoglutarate in a Low-Protein Diet on Fatty Acid Composition and Lipid Metabolism Related Gene Expression in Muscles of Growing Pigs. Chen J, Zhang H, Gao H, Kang B, Chen F, Li Y, Fu C, Yao K		2019
Pathophysiologic mechanisms of obesity- and chronic inflammation-related genes in etiology of polycystic ovary syndrome. Shaaban Z, Khoradmehr A, Amiri-Yekta A, Jafarzadeh Shirazi MR, Tamadon A	Iranian Journal of Basic Medical Sciences	2019
Effect of all-trans retinoic acid on casein and fatty acid synthesis in MAC-T cells. Liao XD, Zhou CH, Zhang J, Shen JL, Wang YJ, Jin YC, Li SL	Asian-Australasian Journal of Animal Sciences	2019
PMP22 Regulates Cholesterol Trafficking and ABCA1-Mediated Cholesterol Efflux Zhou Y, Miles JR, Tavori H, Lin M, Khoshbouei H, Borchelt DR, Bazick H, Landreth GE, Lee S, Fazio S, Notterpek L	Journal of Neuroscience	2019
Chitosan Oligosaccharide Attenuates Nonalcoholic Fatty Liver Disease Induced by High Fat Diet through Reducing Lipid Accumulation, Inflammation and Oxidative Stress in C57BL/6 Mice Tao W, Sun W, Liu L, Wang G, Xiao Z, Pei X, Wang M	Marine drugs	2019
Heterozygous Disruption of Beclin 1 Alleviates Zinc Oxide Nanoparticles-Induced Disturbance of Cholesterol Biosynthesis in Mouse Liver Liu X, Wang B, Jiang X, Zhang J, Tang Q, Zhang Y, Qin X, Chen C, Zou Z	International Journal of Nanomedicine	2019
Comparative RNA-sequencing profiled the differential gene expression of liver in response to acetyl-CoA carboxylase inhibitor GS-0976 in a mouse model of NASH Lu Y, Su X, Zhao M, Zhang Q, Liu C, Lai Q, Wu S, Fang A, Yang J, Chen X, Yao Y	PeerJ	2019
Nifuroxazide ameliorates lipid and glucose metabolism in palmitate-induced HepG2 cells Liu JY, Zhang YC, Song LN, Zhang L, Yang FY, Zhu XR, Cheng ZQ, Cao X, Yang JK	RSC Advances	2019
SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target. Yuan S, Chu H, Chan JF, Ye ZW, Wen L, Yan B, Lai PM, Tee KM, Huang J, Chen D, Li C, Zhao X, Yang D, Chiu MC, Yip C, Poon VK, Chan CC, Sze KH, Zhou J, Chan IH, Kok KH, To KK, Kao RY, Lau JY, Jin DY, Perlman S, Yuen KY	Nature Communications	2019
Epidermal growth factor receptor inhibition attenuates non-alcoholic fatty liver disease in diet-induced obese mice. Choung S, Kim JM, Joung KH, Lee ES, Kim HJ, Ku BJ	PloS one	2019
Metallopeptidase Stp1 activates the transcription factor Sre1 in the carotenogenic yeast Xanthophyllomyces dendrorhous. Gómez M, Gutiérrez MS, González AM, Gárate-Castro C, Sepúlveda D, Barahona S, Baeza M, Cifuentes V, Alcaíno J	Journal of lipid research	2019
Nostoc sphaeroids Kütz powder ameliorates diet-induced hyperlipidemia in C57BL/6j mice. Wei F, Liu Y, Bi C, Zhang B	Food & Nutrition Research	2019
Inhibition of Insulin-Like Growth Factor-1-Induced Sebum Production by Bilobetin in Cultured Human Sebocytes. Wang C, Hwang YL, Li XM, Kim SJ, Zhu MJ, Lee JH, Jiang RH, Kim CD	Annals of Dermatology	2019
Long-Term Feeding of Soy Protein Attenuates Choline Deficient-Induced Adverse Effects in Wild Type Mice and Prohibitin 1 Deficient Mice Response More Sensitively Heo G, Ko KS	Preventive Nutrition and Food Science	2019
Ursodeoxycholic acid ameliorates hepatic lipid metabolism in LO2 cells by regulating the AKT/mTOR/SREBP-1 signaling pathway Hu J, Hong W, Yao KN, Zhu XH, Chen ZY, Ye L	World Journal of Gastroenterology	2019
Role of Neutral Sphingomyelinase-2 (NSM 2) in the Control of T Cell Plasma Membrane Lipid Composition and Cholesterol Homeostasis Börtlein C, Schumacher F, Kleuser B, Dölken L, Avota E	Frontiers in Cell and Developmental Biology	2019
Serum miR-33a is associated with steatosis and inflammation in patients with non-alcoholic fatty liver disease after liver transplantation Erhartova D, Cahova M, Dankova H, Heczkova M, Mikova I, Sticova E, Spicak J, Seda O, Trunecka P	PloS one	2019
Camellia (Camellia oleifera Abel.) seed oil promotes milk fat and protein synthesis‐related gene expression in bovine mammary epithelial cells Zhong W, Shen J, Liao X, Liu X, Zhang J, Zhou C, Jin Y	Food Science & Nutrition	2019
Science, Serendipity and the Single Degree Helen H. Hobbs	Journal of Clinical Investigation	2018
Sustained SREBP-1-dependent lipogenesis as a key mediator of resistance to BRAF-targeted therapy A Talebi, J Dehairs, F Rambow, A Rogiers, D Nittner, R Derua, F Vanderhoydonc, JA Duarte, F Bosisio, KV den Eynde, K Nys, MV Pérez, P Agostinis, E Waelkens, JV den Oord, SM Fendt, JC Marine, JV Swinnen	Nature Communications	2018
Cholesterol negatively regulates IL-9–producing CD8 + T cell differentiation and antitumor activity X Ma, E Bi, C Huang, Y Lu, G Xue, X Guo, A Wang, M Yang, J Qian, C Dong, Q Yi	Journal of Experimental Medicine	2018
Fatty acid synthase mediates EGFR palmitoylation in EGFR mutated non‐small cell lung cancer A Ali, E Levantini, JT Teo, J Goggi, JG Clohessy, CS Wu, L Chen, H Yang, I Krishnan, O Kocher, J Zhang, RA Soo, K Bhakoo, TM Chin, DG Tenen	EMBO Molecular Medicine	2018
Fibroblast Growth Factor Binding Protein 3 (FGFBP3) impacts carbohydrate and lipid metabolism E Tassi, KA Garman, MO Schmidt, X Ma, KW Kabbara, A Uren, Y Tomita, R Goetz, M Mohammadi, CS Wilcox, AT Riegel, M Carlstrom, A Wellstein	Scientific Reports	2018
Fenugreek (Trigonella Foenum-Graecum) Seed Flour and Diosgenin Preserve Endothelium-Dependent Arterial Relaxation in a Rat Model of Early-Stage Metabolic Syndrome K Szabó, R Gesztelyi, N Lampé, R Kiss, J Remenyik, G Pesti-Asbóth, D Priksz, Z Szilvássy, B Juhász	International journal of molecular sciences	2018
Mechanisms of Insulin Action and Insulin Resistance MC Petersen, GI Shulman	Physiological reviews	2018
Genetic Ablation of miR-33 Increases Food Intake, Enhances Adipose Tissue Expansion, and Promotes Obesity and Insulin Resistance NL Price, AK Singh, N Rotllan, L Goedeke, A Wing, A Canfrán-Duque, A Diaz-Ruiz, E Araldi, Á Baldán, JP Camporez, Y Suárez, MS Rodeheffer, GI Shulman, R Cabo, C Fernández-Hernando	Cell Reports	2018
Non-coding RNAs in lipid metabolism X Zhang, NL Price, C Fernández-Hernando	Vascular Pharmacology	2018
Interplay between ChREBP and SREBP-1c coordinates postprandial glycolysis and lipogenesis in livers of mice AG Linden, S Li, HY Choi, F Fang, M Fukasawa, K Uyeda, RE Hammer, JD Horton, LJ Engelking, G Liang	Journal of lipid research	2018
Loss of progesterone receptor membrane component 1 promotes hepatic steatosis via the induced de novo lipogenesis SR Lee, SW Kwon, P Kaya, YH Lee, JG Lee, G Kim, GS Lee, IJ Baek, EJ Hong	Scientific Reports	2018
Targeting immuno-metabolism to improve anti-cancer therapies K Beezhold, CA Byersdorfer	Cancer Letters	2018
LXRɑ participates in the mTOR/S6K1/SREBP-1c signaling pathway during sodium palmitate-induced lipogenesis in HepG2 cells Y Zhou, S Yu, C Cai, L Zhong, H Yu, W Shen	Nutrition & Metabolism	2018
Hepatic lipid homeostasis by peroxisome proliferator-activated receptor gamma 2 YK Lee, JE Park, M Lee, JP Hardwick	Liver Research	2018
Resolving the Paradox of Hepatic Insulin Resistance D Santoleri, PM Titchenell	CMGH Cellular and Molecular Gastroenterology and Hepatology	2018
Increased intracellular iron in mouse primary hepatocytes in vitro causes activation of the Akt pathway but decreases its response to insulin J Varghese, J James, S Vaulont, A Mckie, M Jacob	Biochimica et Biophysica Acta (BBA) - General Subjects	2018
FXR activation by obeticholic acid or nonsteroidal agonists induces a human-like lipoprotein cholesterol change in mice with humanized chimeric liver R Papazyan, X Liu, J Liu, B Dong, EM Plummer, RD Lewis, JD Roth, MA Young	Journal of lipid research	2018
Role of SREBPs in Liver Diseases: A Mini-review A Moslehi, Z Hamidi-zad	Journal of Clinical and Translational Hepatology	2018
Chinese olive extract ameliorates hepatic lipid accumulation in vitro and in vivo by regulating lipid metabolism YT Yeh, YY Cho, SC Hsieh, AN Chiang	Scientific Reports	2018
Impact of silencing hepatic SREBP-1 on insulin signaling V Jideonwo, Y Hou, M Ahn, S Surendran, N Morral, RM Luque	PloS one	2018
Distinct correlations between lipogenic gene expression and fatty acid composition of subcutaneous fat among cattle breeds D Gamarra, N Aldai, A Arakawa, LJ Barron, A López-Oceja, MM de Pancorbo, M Taniguchi	BMC veterinary research	2018
Lipid metabolism reprogramming and its potential targets in cancer C Cheng, F Geng, X Cheng, D Guo		2018
Implementation of environmental enrichment after middle age promotes healthy aging T McMurphy, W Huang, NJ Queen, S Ali, KJ Widstrom, X Liu, R Xiao, JJ Siu, L Cao	Aging	2018
Role of hepatoma-derived growth factor in promoting de novo lipogenesis and tumorigenesis in hepatocellular carcinoma X Min, J Wen, L Zhao, K Wang, Q Li, G Huang, J Liu, X Zhao	Molecular Oncology	2018
N,N-Dimethyl-3β-hydroxycholenamide Reduces Retinal Cholesterol via Partial Inhibition of Retinal Cholesterol Biosynthesis Rather Than its Liver X Receptor Transcriptional Activity N El-Darzi, A Astafev, N Mast, A Saadane, M Lam, IA Pikuleva	Frontiers in pharmacology	2018
Diet-Induced Circadian Enhancer Remodeling Synchronizes Opposing Hepatic Lipid Metabolic Processes D Guan, Y Xiong, PC Borck, C Jang, PT Doulias, R Papazyan, B Fang, C Jiang, Y Zhang, ER Briggs, W Hu, D Steger, H Ischiropoulos, JD Rabinowitz, MA Lazar	Cell	2018
Plasma PCSK9 correlates with apoB-48-containing triglyceride-rich lipoprotein production in men with insulin resistance JP Drouin-Chartier, AJ Tremblay, JC Hogue, V Lemelin, B Lamarche, P Couture	Journal of lipid research	2018
BHLHE40, a third transcription factor required for insulin induction of SREBP-1c mRNA in rodent liver J Tian, J Wu, X Chen, T Guo, ZJ Chen, JL Goldstein, MS Brown	eLife	2018
Functional Comparison of High and Low Molecular Weight Chitosan on Lipid Metabolism and Signals in High-Fat Diet-Fed Rats SH Liu, CY Chiu, CM Shi, MT Chiang	Marine drugs	2018
Nutrients and Oxidative Stress: Friend or Foe? BL Tan, ME Norhaizan, WP Liew	Oxidative medicine and cellular longevity	2018
Pathophysiology of Diabetic Dyslipidemia T Hirano	Journal of Atherosclerosis and Thrombosis	2018
A Component Formula of Chinese Medicine for Hypercholesterolemia Based on Virtual Screening and Biology Network X Huo, F Lu, L Qiao, G Li, Y Zhang	Evidence-Based Complementary and Alternative Medicine	2018
Underlying mechanisms for sterol-induced ubiquitination and ER-associated degradation of HMG CoA reductase BM Johnson, RA DeBose-Boyd	Seminars in Cell & Developmental Biology	2018
miR-122 Regulates LHR Expression in Rat Granulosa Cells by Targeting Insig1 mRNA B Menon, X Guo, N Garcia, T Gulappa, KM Menon	Endocrinology	2018
SREBPs in Lipid Metabolism, Insulin Signaling, and Beyond RA DeBose-Boyd, J Ye	Trends in Biochemical Sciences	2018
The liver X receptors and sterol regulatory element binding proteins alter progesterone secretion and are regulated by human chorionic gonadotropin in human luteinized granulosa cells Y Xu, JJ Hernández-Ledezma, SM Hutchison, RL Bogan	Molecular and Cellular Endocrinology	2018
Insulin/Snail1 axis ameliorates fatty liver disease by epigenetically suppressing lipogenesis Y Liu, L Jiang, C Sun, N Ireland, YM Shah, Y Liu, L Rui	Nature Communications	2018
Effects of vitamin D on insulin resistance and myosteatosis in diet-induced obese mice E Benetti, R Mastrocola, F Chiazza, D Nigro, G DAntona, V Bordano, R Fantozzi, M Aragno, M Collino, MA Minetto, MB Aguila	PloS one	2018
Inactivation of SREBP-1a Phosphorylation Prevents Fatty Liver Disease in Mice: Identification of Related Signaling Pathways by Gene Expression Profiles in Liver and Proteomes of Peroxisomes B Knebel, S Hartwig, S Jacob, U Kettel, M Schiller, W Passlack, C Koellmer, S Lehr, D Müller-Wieland, J Kotzka	International journal of molecular sciences	2018
The lysolipid transporter Mfsd2a regulates lipogenesis in the developing brain JP Chan, BH Wong, CF Chin, DL Galam, JC Foo, LC Wong, S Ghosh, MR Wenk, A Cazenave-Gassiot, DL Silver, R Daneman	PLoS Biology	2018
Ethanol extract of Allium fistulosum inhibits development of non-alcoholic fatty liver disease JT Hwang, EJ Shin, MY Chung, JH Park, S Chung, HK Choi	Nutrition Research and Practice	2018
Sauchinone controls hepatic cholesterol homeostasis by the negative regulation of PCSK9 transcriptional network HS Chae, BH You, DY Kim, H Lee, HW Ko, HJ Ko, YH Choi, SS Choi, YW Chin	Scientific Reports	2018
Downregulation of SREBP inhibits tumor growth and initiation by altering cellular metabolism in colon cancer YA Wen, X Xiong, YY Zaytseva, DL Napier, E Vallee, AT Li, C Wang, HL Weiss, BM Evers, T Gao	Cell Death and Disease	2018
IL-36/LXR axis modulates cholesterol metabolism and immune defense to Mycobacterium tuberculosis F Ahsan, J Maertzdorf, U Guhlich-Bornhof, SH Kaufmann, P Moura-Alves	Scientific Reports	2018
Trafficking of cholesterol to the ER is required for NLRP3 inflammasome activation M de la Roche, C Hamilton, R Mortensen, AA Jeyaprakash, S Ghosh, PK Anand	The Journal of Cell Biology	2018
Curcumin and dietary polyphenol research: beyond drug discovery T Jin	Acta Pharmacologica Sinica	2018
Social status affects lipid metabolism in rainbow trout, Oncorhynchus mykiss DJ Kostyniuk, BM Culbert, JA Mennigen, KM Gilmour	American Journal of Physiology - Regulatory, Integrative and Comparative Physiology	2018
Key regulators of lipid metabolism drive endocrine resistance in invasive lobular breast cancer T Du, MJ Sikora, KM Levine, N Tasdemir, RB Riggins, SG Wendell, BV Houten, S Oesterreich	Breast Cancer Research	2018
Effects of Dietary Intake of Japanese Mushrooms on Visceral Fat Accumulation and Gut Microbiota in Mice T Shimizu, K Mori, K Ouchi, M Kushida, T Tsuduki	Nutrients	2018
Novel Neohesperidin Dihydrochalcone Analogue Inhibits Adipogenic Differentiation of Human Adipose-Derived Stem Cells through the Nrf2 Pathway G Han, HT Kang, S Chung, C Lim, J Linton, JH Lee, W Kim, SH Kim, J Lee	International journal of molecular sciences	2018
Aqueous Extract of Pepino (Solanum muriactum Ait) Leaves Ameliorate Lipid Accumulation and Oxidative Stress in Alcoholic Fatty Liver Disease JY Hsu, HH Lin, CC Hsu, BC Chen, JH Chen	Nutrients	2018
Cholesterol metabolism—physiological regulation and pathophysiological deregulation by the endoplasmic reticulum C Röhrl, H Stangl	Wiener Medizinische Wochenschrift	2018
Endosomal-Lysosomal Cholesterol Sequestration by U18666A Differentially Regulates Amyloid Precursor Protein (APP) Metabolism in Normal and APP-Overexpressing Cells J Chung, G Phukan, D Vergote, A Mohamed, M Maulik, M Stahn, RJ Andrew, G Thinakaran, EP de Chaves, S Kar	Molecular and cellular biology	2018
mTOR and Tumor Cachexia A Duval, C Jeanneret, T Santoro, O Dormond	International journal of molecular sciences	2018
High-content screen for modifiers of Niemann-Pick type C disease in patient cells EK Pugach, MK Feltes, RJ Kaufman, DS Ory, AG Bang	Human Molecular Genetics	2018
Fluoxetine induces lipid metabolism abnormalities by acting on the liver in patients and mice with depression S Pan, Y Tan, S Yao, Y Xin, X Yang, J Liu, J Xiong	Acta Pharmacologica Sinica	2018
The utility of noninvasive scores in assessing the prevalence of nonalcoholic fatty liver disease and advanced fibrosis in type 1 diabetic patients A Singh, P Le, R Lopez, N Alkhouri	Hepatology International	2018
Truncated Adenomatous Polyposis Coli Mutation Induces Asef-Activated Golgi Fragmentation SB Kim, L Zhang, J Yoon, J Lee, J Min, W Li, NV Grishin, YA Moon, WE Wright, JW Shay	Molecular and cellular biology	2018
Reversal of metabolic disorders by pharmacological activation of bile acid receptors TGR5 and FXR K Jadhav, Y Xu, Y Xu, Y Li, J Xu, Y Zhu, L Adorini, YK Lee, T Kasumov, L Yin, Y Zhang	Molecular Metabolism	2018
Water-Soluble Fish Protein Intake Led to Lower Serum and Liver Cholesterol Concentrations in Obese Zucker fa/fa Rats A Drotningsvik, L Vikøren, S Mjøs, Å Oterhals, D Pampanin, O Flesland, O Gudbrandsen	Marine drugs	2018
Inhibition of low-density lipoprotein receptor degradation with a cyclic peptide that disrupts the homodimerization of IDOL E3 ubiquitin ligase EK Leitch, N Elumalai, M Fridén-Saxin, G Dahl, P Wan, P Clarkson, E Valeur, G Pairaudeau, H Boyd, A Tavassoli	Chemical Science	2018
Intake of 3 Eggs per Day When Compared to a Choline Bitartrate Supplement, Downregulates Cholesterol Synthesis without Changing the LDL/HDL Ratio B Lemos, I Medina-Vera, C Blesso, M Fernandez	Nutrients	2018
Stanniocalcin 2 Ameliorates Hepatosteatosis Through Activation of STAT3 Signaling J Zhao, Y Jiao, Y Song, J Liu, X Li, H Zhang, J Yang, Y Lu	Frontiers in physiology	2018
Rapid communication: lipid metabolic gene expression and triacylglycerol accumulation in goat mammary epithelial cells are decreased by inhibition of SREBP-1 H Xu, J Luo, H Tian, J Li, X Zhang, Z Chen, M Li, JJ Loor	Journal of animal science	2018
Tetrahydrocurcumin ameliorates free fatty acid-induced hepatic steatosis and improves insulin resistance in HepG2 cells JW Chen, ZL Kong, ML Tsai, CY Lo, CT Ho, CS Lai	Journal of Food and Drug Analysis	2018
Retrospective on Cholesterol Homeostasis: The Central Role of Scap MS Brown, A Radhakrishnan, JL Goldstein	Annual Review of Biochemistry	2018
miR-203 Inhibits Alcohol-Induced Hepatic Steatosis by Targeting Lipin1 XY Cheng, JD Liu, XY Lu, X Yan, C Huang, XM Meng, J Li	Frontiers in pharmacology	2018
Effect of brimonidine, an α2 adrenergic agonist, on human meibomian gland epithelial cells , Y Liu, WR Kam, DA Sullivan	Experimental Eye Research	2018
Developmental and extrahepatic physiological functions of SREBP pathway genes in mice LJ Engelking, MJ Cantoria, Y Xu, G Liang	Seminars in Cell & Developmental Biology	2018
Milk lipid regulation at the maternal-offspring interface D Yang, HD Huynh, Y Wan	Seminars in Cell & Developmental Biology	2018
Pharmacogenomics of Chemically Distinct Classes of Keap1-Nrf2 Activators Identify Common and Unique Gene, Protein, and Pathway Responses In Vivo RS Wible, QT Tran, S Fathima, CH Sutter, TW Kensler, TR Sutter	Molecular pharmacology	2018
Sterol Metabolism and Transport in Atherosclerosis and Cancer Y Yamauchi, MA Rogers	Frontiers in Endocrinology	2018
The peroxisome: an update on mysteries 2.0 M Islinger, A Voelkl, HD Fahimi, M Schrader	Histochemistry and Cell Biology	2018
Farnesoid X Receptor Activation by Obeticholic Acid Elevates Liver Low-Density Lipoprotein Receptor Expression by mRNA Stabilization and Reduces Plasma Low-Density Lipoprotein Cholesterol in Mice AB Singh, B Dong, FB Kraemer, Y Xu, Y Zhang, J Liu	Arteriosclerosis, thrombosis, and vascular biology	2018
Regulatory Efficacy of the Polyunsaturated Fatty Acids from Microalgae Spirulina platensis on Lipid Metabolism and Gut Microbiota in High-Fat Diet Rats TT Li, YY Liu, XZ Wan, ZR Huang, B Liu, C Zhao	International journal of molecular sciences	2018
Molecular pathways of nonalcoholic fatty liver disease development and progression F Bessone, MV Razori, MG Roma	Cellular and Molecular Life Sciences	2018
Lipid mediators of liver injury in nonalcoholic fatty liver disease S Liangpunsakul, N Chalasani	AJP Gastrointestinal and Liver Physiology	2018
Familial Hypercholesterolemia: The Most Frequent Cholesterol Metabolism Disorder Caused Disease A Benito-Vicente, K Uribe, S Jebari, U Galicia-Garcia, H Ostolaza, C Martin	International journal of molecular sciences	2018
Retinal Cholesterol Content Is Reduced in Simvastatin-Treated Mice Due to Inhibited Local Biosynthesis Albeit Increased Uptake of Serum Cholesterol N Mast, IR Bederman, IA Pikuleva	Drug Metabolism and Disposition	2018
Cholesterol metabolism in innate and adaptive response A Reboldi, E Dang	F1000Research	2018
Acetyl-CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents: Hepatology L Goedeke, J Bates, DF Vatner, RJ Perry, T Wang, R Ramirez, L Li, MW Ellis, D Zhang, KE Wong, C Beysen, GW Cline, AS Ray, GI Shulman	Hepatology	2018
Retinal Vascular Abnormalities and Microglia Activation in Mice with Deficiency in Cytochrome P450 46A1–Mediated Cholesterol Removal A Saadane, N Mast, G Trichonas, D Chakraborty, S Hammer, JV Busik, MB Grant, IA Pikuleva	The American Journal of Pathology	2018
Maternal Protein Restriction Induces Alterations in Hepatic Unfolded Protein Response-Related Molecules in Adult Rat Offspring X Liu, J Wang, L Gao, Y Jiao, C Liu	Frontiers in Endocrinology	2018
Eicosapentaenoic acid in combination with EPHA2 inhibition shows efficacy in preclinical models of triple-negative breast cancer by disrupting cellular cholesterol efflux AM Torres-Adorno, H Vitrac, Y Qi, L Tan, KR Levental, YY Fan, P Yang, RS Chapkin, BL Eckhardt, NT Ueno	Oncogene	2018
Hypothalamic gene transfer of BDNF promotes healthy aging in mice T McMurphy, W Huang, X Liu, JJ Siu, NJ Queen, R Xiao, L Cao	Aging Cell	2018
Role of MicroRNAs in Pathophysiology of Non-alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis F Iravani, N Hosseini, M Mojarrad	Middle East journal of digestive diseases	2018
Isoquercetin Improves Hepatic Lipid Accumulation by Activating AMPK Pathway and Suppressing TGF-β Signaling on an HFD-Induced Nonalcoholic Fatty Liver Disease Rat Model G Qin, J Ma, Q Huang, H Yin, J Han, M Li, Y Deng, B Wang, W Hassan, J Shang	International journal of molecular sciences	2018
Development and Application of FASA, a Model for Quantifying Fatty Acid Metabolism Using Stable Isotope Labeling JP Argus, MQ Wilks, QD Zhou, WY Hsieh, E Khialeeva, XP Hoi, V Bui, S Xu, AK Yu, ES Wang, HR Herschman, KJ Williams, SJ Bensinger	Cell Reports	2018
CtBP promotes metastasis of breast cancer through repressing cholesterol and activating TGF-β signaling Z Zhao, D Hao, L Wang, J Li, Y Meng, P Li, Y Wang, C Zhang, H Zhou, K Gardner, L Di	Oncogene	2018
Anti‐hyperlipidaemic effects of synthetic analogues of nordihydroguaiaretic acid in dyslipidaemic rats M Singh, S Bittner, Y Li, A Bittner, L Han, Y Cortez, M Inayathullah, Z Arif, R Parthasarathi, J Rajadas, WJ Shen, MR Nicolls, FB Kraemer, S Azhar	British Journal of Pharmacology	2018
p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression SH Moon, CH Huang, SL Houlihan, K Regunath, WA Freed-, JP Morris, DF Tschaharganeh, ER Kastenhuber, AM Barsotti, R Culp-Hill, W Xue, YJ Ho, T Baslan, X Li, A Mayle, E de Stanchina, L Zender, DR Tong, A DAlessandro, SW Lowe, C Prives	Cell	2018
Per-Arnt-Sim Kinase (PASK) Deficiency Increases Cellular Respiration on a Standard Diet and Decreases Liver Triglyceride Accumulation on a Western High-Fat High-Sugar Diet J Pape, C Newey, H Burrell, A Workman, K Perry, B Bikman, L Bridgewater, J Grose	Nutrients	2018
CVB3 Nonstructural 2A Protein Modulates SREBP1a Signaling via the MEK/ERK Pathway L Wang, W Xie, L Zhang, D Li, H Yu, J Xiong, J Peng, J Qiu, H Sheng, X He, K Zhang, JK Pfeiffer	Journal of virology	2018
The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1 SA Menzies, N Volkmar, DJ van den Boomen, RT Timms, AS Dickson, JA Nathan, PJ Lehner	eLife	2018
Carvacrol reduces adipogenic differentiation by modulating autophagy and ChREBP expression S Spalletta, V Flati, E Toniato, JD Gregorio, A Marino, L Pierdomenico, M Marchisio, G DOrazi, I Cacciatore, I Robuffo, V Trajkovic	PloS one	2018
Blocking FSH inhibits hepatic cholesterol biosynthesis and reduces serum cholesterol Y Guo, M Zhao, T Bo, S Ma, Z Yuan, W Chen, Z He, X Hou, J Liu, Z Zhang, Q Zhu, Q Wang, X Lin, Z Yang, M Cui, L Liu, Y Li, C Yu, X Qi, Q Wang, H Zhang, Q Guan, L Zhao, S Xuan, H Yan, Y Lin, L Wang, Q Li, Y Song, L Gao, J Zhao	Cell Research	2018
Dysregulation of cardiac lipid parameters in high-fat high-cholesterol diet-induced rat model Q Han, SC Yeung, MS Ip, JC Mak	Lipids in Health and Disease	2018
Palmitate-Induced SREBP1 Expression and Activation Underlies the Increased BACE 1 Activity and Amyloid Beta Genesis G Marwarha, K Claycombe-Larson, J Lund, O Ghribi	Molecular Neurobiology	2018
Ring finger protein 145 (RNF145) is a ubiquitin ligase for sterol-induced degradation of HMG-CoA reductase LY Jiang, W Jiang, N Tian, YN Xiong, J Liu, J Wei, KY Wu, J Luo, XJ Shi, BL Song	The Journal of biological chemistry	2018
Understanding the diversity of membrane lipid composition T Harayama, H Riezman	Nature Reviews Molecular Cell Biology	2018
LDL Cholesterol Uptake Assay Using Live Cell Imaging Analysis with Cell Health Monitoring P Ritter, K Yousefi, J Ramirez, DM Dykxhoorn, AJ Mendez, LA Shehadeh	Journal of visualized experiments : JoVE	2018
Ad4BP/SF-1 regulates cholesterol synthesis to boost the production of steroids. Baba T, Otake H, Inoue M, Sato T, Ishihara Y, Moon JY, Tsuchiya M, Miyabayashi K, Ogawa H, Shima Y, Wang L, Sato R, Yamazaki T, Suyama M, Nomura M, Choi MH, Ohkawa Y, Morohashi KI		2018
The Antidiabetic Drug Lobeglitazone Protects Mice From Lipogenesis-Induced Liver Injury via Mechanistic Target of Rapamycin Complex 1 Inhibition. Lee YS, Park JS, Lee DH, Lee DK, Kwon SW, Lee BW, Bae SH	Frontiers in Endocrinology	2018
Phosphatidylcholine and phosphatidylethanolamine plasmalogens in lipid loaded human macrophages. Wallner S, Orsó E, Grandl M, Konovalova T, Liebisch G, Schmitz G	PloS one	2018
Hepatic lesions induced by feeding Western diets to Zucker fatty rats, an insulin-resistant model. Saito T, Toriniwa Y, Ishii Y, Uemura A, Miyajima K, Uno K, Shirai Y, Nakae D, Ohta T	Journal of Toxicologic Pathology	2018
Circulating miRNA measurements are reflective of cholesterol-based changes in rainbow trout (Oncorhynchus mykiss). Zhu T, Corraze G, Plagnes-Juan E, Skiba-Cassy S	PloS one	2018
Hypoxia: A breath of fresh air for the meibomian gland. Liu Y, Chen D, Chen X, Kam WR, Hatton MP, Sullivan DA	The ocular surface	2018
Roles for ER:endosome membrane contact sites in ligand-stimulated intraluminal vesicle formation Wong LH, Eden ER, Futter CE	Biochemical Society Transactions	2018
SCAP/SREBPs Are Central Players in Lipid Metabolism and Novel Metabolic Targets in Cancer Therapy Cheng X, Li J, Guo D	Current topics in medicinal chemistry	2018
Epidemiology: Chronic disease, cancer, and exercise - a common link. Allegretti AS, Thadhani RI	Nature reviews. Nephrology	2018
Capsaicinoids improve consequences of physical activity. Sahin K, Orhan C, Tuzcu M, Sahin N, Erten F, Juturu V	Toxicology Reports	2018
Specific Amino Acids Affect Cardiovascular Diseases and Atherogenesis via Protection against Macrophage Foam Cell Formation: Review Article. Grajeda-Iglesias C, Aviram M	Rambam Maimonides Medical Journal	2018
Assimilation and discrimination of hydrogen isotopes in a terrestrial mammal. Rodriguez Curras M, Fogel ML, Newsome SD	Oecologia	2018
Long non‑coding RNA HR1 participates in the expression of SREBP‑1c through phosphorylation of the PDK1/AKT/FoxO1 pathway. Li D, Guo L, Deng B, Li M, Yang T, Yang F, Yang Z	Molecular medicine reports	2018
Dynamic MTORC1-TFEB feedback signaling regulates hepatic autophagy, steatosis and liver injury in long-term nutrient oversupply. Zhang H, Yan S, Khambu B, Ma F, Li Y, Chen X, Martina JA, Puertollano R, Li Y, Chalasani N, Yin XM	Autophagy	2018
Cholesterol pathway the Achilles heel in prostate cancer metastasis. Heidegger I, Pichler R, Pircher A	Translational andrology and urology	2018
A SUMO-dependent LRH-1/OSBP pathway promoting nonalcoholic fatty liver disease Sokrates Stein, Vera Lemos, Pan Xu, Hadrien Demagny, Xu Wang, Dongryeol Ryu, Veronica Jimenez, Fàtima Bosch, Thomas Lüscher, Maaike Oosterveer, Kristina Schoonjans	Journal of Clinical Investigation	2017
ChREBP mediates metabolic adaptation to fructose intake and prevents fructose-rich diet-induced hepatotoxicity Deqiang Zhang, xin Tong, Kyle VanDommelen, Neil Gupta, Kenneth Stamper, Graham Brady, Zhuo-Xian Meng, Jiandie Lin, Liangyou Rui, Bishr Omary, Lei Yin	Journal of Clinical Investigation	2017
Dichotomous Effects of Glucose and Fructose on Hepatic Lipogenesis and Insulin Signaling Samir Softic, Manoj Gupta, Guo-Xiao Wang, Shiho Fujisaka, Brian O’Neill, TN Rao, Jennifer Willoughby, Carole Harbison, Kevin Fitzgerald, Olga Ilkayeva, Christopher B. Newgard, David Cohen, C. Ronald Kahn	Journal of Clinical Investigation	2017
RNF20 Suppresses Tumorigenesis by Inhibiting the SREBP1c-PTTG1 Axis in Kidney Cancer JH Lee, YG Jeon, KH Lee, HW Lee, J Park, H Jang, M Kang, HS Lee, HJ Cho, DH Nam, C Kwak, JB Kim	Molecular and cellular biology	2017
Metabolism dysregulation induces a specific lipid signature of nonalcoholic steatohepatitis in patients F Chiappini, A Coilly, H Kadar, P Gual, A Tran, C Desterke, D Samuel, JC Duclos-Vallée, D Touboul, J Bertrand-Michel, A Brunelle, C Guettier, FL Naour	Scientific Reports	2017
SREBP-regulated lipid metabolism: convergent physiology — divergent pathophysiology H Shimano, R Sato	Nature Reviews Endocrinology	2017
mTORC1 signaling in hepatic lipid metabolism J Han, Y Wang	Protein & Cell	2017
A distinct function of the retinoblastoma protein in the control of lipid composition identified by lipidomic profiling H Muranaka, A Hayashi, K Minami, S Kitajima, S Kohno, Y Nishimoto, N Nagatani, M Suzuki, LA Kulathunga, N Sasaki, N Okada, T Matsuzaka, H Shimano, H Tada, C Takahashi	Oncogenesis	2017
MicroRNAs and lipid metabolism: B Aryal, AK Singh, N Rotllan, N Price, C Fernández-Hernando	Current Opinion in Lipidology	2017
Genetic Dissection of the Impact of miR-33a and miR-33b during the Progression of Atherosclerosis NL Price, N Rotllan, A Canfrán-Duque, X Zhang, P Pati, N Arias, J Moen, M Mayr, DA Ford, Á Baldán, Y Suárez, C Fernández-Hernando	Cell Reports	2017
Posttranscriptional regulation of lipid metabolism by non-coding RNAs and RNA binding proteins AK Singh, B Aryal, X Zhang, Y Fan, NL Price, Y Suárez, C Fernández-Hernando	Seminars in Cell & Developmental Biology	2017
Unraveling the Regulation of Hepatic Metabolism by Insulin PM Titchenell, MA Lazar, MJ Birnbaum	Trends in Endocrinology & Metabolism	2017
Fructose and glucose can regulate mammalian target of rapamycin complex 1 and lipogenic gene expression via distinct pathways Y Hu, I Semova, X Sun, H Kang, S Chahar, AN Hollenberg, D Masson, MD Hirschey, J Miao, SB Biddinger	The Journal of biological chemistry	2017
Aliskiren effect on non-alcoholic steatohepatitis in metabolic syndrome FN Ramalho, SC Sanches, MC Foss, MJ Augusto, DM Silva, AM Oliveira, LN Ramalho	Diabetology & metabolic syndrome	2017
Emerging roles of SIRT1 in fatty liver diseases RB Ding, J Bao, CX Deng	International journal of biological sciences	2017
Biochemical and cellular properties of insulin receptor signalling RA Haeusler, TE McGraw, D Accili	Nature Reviews Molecular Cell Biology	2017
Combined transcriptome and metabolome analyses of metformin effects reveal novel links between metabolic networks in steroidogenic systems SS Udhane, B Legeza, N Marti, D Hertig, G Diserens, JM Nuoffer, P Vermathen, CE Flück	Scientific Reports	2017
Canonical microRNAs Enable Differentiation, Protect Against DNA Damage, and Promote Cholesterol Biosynthesis in Neural Stem Cells Z Liu, C Zhang, A Khodadadi-Jamayran, L Dang, X Han, K Kim, H Li, R Zhao	Stem Cells and Development	2017
Pro-inflammation NF-κB signaling triggers a positive feedback via enhancing cholesterol accumulation in liver cancer cells M He, W Zhang, Y Dong, L Wang, T Fang, W Tang, B Lv, G Chen, B Yang, P Huang, J Xia	Journal of Experimental & Clinical Cancer Research	2017
Maternal resveratrol intake during lactation attenuates hepatic triglyceride and fatty acid synthesis in adult male rat offspring M Tanaka, T Kita, S Yamasaki, T Kawahara, Y Ueno, M Yamada, Y Mukai, S Sato, M Kurasaki, T Saito	Biochemistry and Biophysics Reports	2017
Molecular regulation of LHCGR expression by miR-122 during follicle growth in the rat ovary B Menon, T Gulappa, KM Menon	Molecular and Cellular Endocrinology	2017
1-Carbon Cycle Metabolites Methylate Their Way to Fatty Liver AK Walker	Trends in Endocrinology & Metabolism	2017
Antidiabetic, Lipid Normalizing, and Nephroprotective Actions of the Strawberry: A Potent Supplementary Fruit P Mandave, S Khadke, M Karandikar, V Pandit, P Ranjekar, A Kuvalekar, N Mantri	International journal of molecular sciences	2017
The SCF β-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis K Shimizu, H Fukushima, K Ogura, EC Lien, NT Nihira, J Zhang, BJ North, A Guo, K Nagashima, T Nakagawa, S Hoshikawa, A Watahiki, K Okabe, A Yamada, A Toker, JM Asara, S Fukumoto, KI Nakayama, K Nakayama, H Inuzuka, W Wei	Science signaling	2017
Aryl hydrocarbon receptor-deficient mice are protected from high fat diet-induced changes in metabolic rhythms C Jaeger, C Xu, M Sun, S Krager, SA Tischkau	Chronobiology International	2017
Loss of Hepatic CEACAM1: A Unifying Mechanism Linking Insulin Resistance to Obesity and Non-Alcoholic Fatty Liver Disease G Heinrich, HE Ghadieh, SS Ghanem, HT Muturi, K Rezaei, QY Al-Share, TA Bowman, D Zhang, RS Garofalo, L Yin, SM Najjar	Frontiers in Endocrinology	2017
Aberrant expression of microRNA induced by high fructose diet: Implications in the pathogenesis of hyperlipidemia and hepatic insulin resistance N Sud, H Zhang, K Pan, X Cheng, J Cui, Q Su	The Journal of Nutritional Biochemistry	2017
Identification of the ER-resident E3 ubiquitin ligase RNF145 as a novel LXR-regulated gene EC Cook, JK Nelson, V Sorrentino, D Koenis, M Moeton, S Scheij, R Ottenhoff, B Bleijlevens, A Loregger, N Zelcer, A Moschetta	PloS one	2017
Role of Phospholipid Flux during Milk Secretion in the Mammary Gland M Smoczyński	Journal of Mammary Gland Biology and Neoplasia	2017
ENOblock, a unique small molecule inhibitor of the non-glycolytic functions of enolase, alleviates the symptoms of type 2 diabetes H Cho, JI Um, JH Lee, WH Kim, WS Kang, SH Kim, HH Ha, YC Kim, YK Ahn, DW Jung, DR Williams	Scientific Reports	2017
Cinnamon Polyphenol Extract Inhibits Hyperlipidemia and Inflammation by Modulation of Transcription Factors in High-Fat Diet-Fed Rats Z Tuzcu, C Orhan, N Sahin, V Juturu, K Sahin	Oxidative medicine and cellular longevity	2017
Expression of SREBP-1c Requires SREBP-2-mediated Generation of a Sterol Ligand for LXR in Livers of Mice S Rong, VA Cortés, S Rashid, NN Anderson, JG McDonald, G Liang, YA Moon, RE Hammer, JD Horton	eLife	2017
Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20 G Liu, L Zhou, H Zhang, R Chen, Y Zhang, L Li, JY Lu, H Jiang, D Liu, S Qi, YM Jiang, K Yin, Z Xie, Y Shi, Y Liu, X Cao, YX Chen, D Zou, WJ Zhang	Nature Communications	2017
The SCAP/SREBP Pathway: A Mediator of Hepatic Steatosis YA Moon	Endocrinology and Metabolism	2017
Human Subtilisin Kexin Isozyme-1 (SKI-1)/Site-1 Protease (S1P) regulates cytoplasmic lipid droplet abundance: A potential target for indirect-acting anti-dengue virus agents A Hyrina, F Meng, SJ McArthur, S Eivemark, IR Nabi, F Jean, P Roques	PloS one	2017
Transglycosylated Starch Improves Insulin Response and Alters Lipid and Amino Acid Metabolome in a Growing Pig Model M Newman, Q Zebeli, E Eberspächer, D Grüll, T Molnar, B Metzler-Zebeli	Nutrients	2017
Uncovering Structural Diversity of Unsaturated Fatty Acyls in Cholesteryl Esters via Photochemical Reaction and Tandem Mass Spectrometry J Ren, ET Franklin, Y Xia	Journal of the American Society for Mass Spectrometry	2017
Lipid droplets and liver disease: from basic biology to clinical implications NL Gluchowski, M Becuwe, TC Walther, RV Farese	Nature Reviews Gastroenterology & Hepatology	2017
Bile acid receptors link nutrient sensing to metabolic regulation J Li, T Li	Liver Research	2017
Inhibition of NAMPT aggravates high fat diet-induced hepatic steatosis in mice through regulating Sirt1/AMPKα/SREBP1 signaling pathway LF Wang, XN Wang, CC Huang, L Hu, YF Xiao, XH Guan, YS Qian, KY Deng, HB Xin	Lipids in Health and Disease	2017
Precise integration of inducible transcriptional elements (PrIITE) enables absolute control of gene expression R Pinto, L Hansen, J Hintze, R Almeida, S Larsen, M Coskun, J Davidsen, C Mitchelmore, L David, JT Troelsen, EP Bennett	Nucleic Acids Research	2017
New insights into the role of Lith genes in the formation of cholesterol-supersaturated bile HH Wang, T Li, P Portincasa, DA Ford, BA Neuschwander-Tetri, P Tso, DQ Wang	Liver Research	2017
Gelidium elegans Regulates the AMPK-PRDM16-UCP-1 Pathway and Has a Synergistic Effect with Orlistat on Obesity-Associated Features in Mice Fed a High-Fat Diet J Choi, KJ Kim, EJ Koh, BY Lee	Nutrients	2017
mTOR Inhibition Subdues Milk Disorder Caused by Maternal VLDLR Loss HD Huynh, W Wei, Y Wan	Cell Reports	2017
ATAD3 gene cluster deletions cause cerebellar dysfunction associated with altered mitochondrial DNA and cholesterol metabolism R Desai, AE Frazier, R Durigon, H Patel, AW Jones, ID Rosa, NJ Lake, AG Compton, HS Mountford, EJ Tucker, AL Mitchell, D Jackson, A Sesay, MD Re, LP van Heuvel, D Burke, D Francis, S Lunke, G McGillivray, S Mandelstam, F Mochel, B Keren, C Jardel, AM Turner, PI Andrews, J Smeitink, JN Spelbrink, SJ Heales, M Kohda, A Ohtake, K Murayama, Y Okazaki, A Lombès, IJ Holt, DR Thorburn, A Spinazzola	Brain	2017
The Role of Lipid and Lipoprotein Metabolism in Non‐Alcoholic Fatty Liver Disease F Perla, M Prelati, M Lavorato, D Visicchio, C Anania	Children	2017
Regulation of INSIG2 by microRNA-96 Y Jo, JY Cha, YA Moon	Animal Cells and Systems	2017
mTORC1 and mTORC2 as regulators of cell metabolism in immunity M Linke, SD Fritsch, N Sukhbaatar, M Hengstschläger, T Weichhart	FEBS Letters	2017
CIDE gene expression in adipose tissue, liver, and skeletal muscle from obese and lean pigs Y Qiu, X Yang, X Ma, Y Xiong, Z Tian, Q Fan, L Wang, Z Jiang	Journal of Zhejiang University SCIENCE B	2017
Epidemiologic Analysis Along the Mevalonate Pathway Reveals Improved Cancer Survival in Patients Who Receive Statins Alone and in Combination With Bisphosphonates SM El-Refai, JD Brown, SM Arnold, EP Black, M Leggas, JC Talbert	JCO Clinical Cancer Informatics	2017
Loss of Calreticulin Uncovers a Critical Role for Calcium in Regulating Cellular Lipid Homeostasis WA Wang, WX Liu, S Durnaoglu, SK Lee, J Lian, R Lehner, J Ahnn, LB Agellon, M Michalak	Scientific Reports	2017
The Role of Lipid Bodies in the Microglial Aging Process and Related Diseases X Hu, B Xu, W Ge	Neurochemical Research	2017
Kmt5a Controls Hepatic Metabolic Pathways by Facilitating RNA Pol II Release from Promoter-Proximal Regions KC Nikolaou, P Moulos, V Harokopos, G Chalepakis, I Talianidis	Cell Reports	2017
Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation CW Kim, C Addy, J Kusunoki, NN Anderson, S Deja, X Fu, SC Burgess, C Li, M Ruddy, M Chakravarthy, S Previs, S Milstein, K Fitzgerald, DE Kelley, JD Horton	Cell Metabolism	2017
Levels of Hepatic Activating Transcription Factor 6 and Caspase-3 Are Downregulated in Mice after Excessive Training AP Pinto, AL da Rocha, LC Oliveira, GP Morais, LG de Vicente, DE Cintra, JR Pauli, LP Moura, ER Ropelle, AS da Silva	Frontiers in Endocrinology	2017
Cholesterol auxotrophy and intolerance to ezetimibe in mice with SREBP-2 deficiency in the intestine S Rong, JG McDonald, LJ Engelking	Journal of lipid research	2017
Srebp-controlled glucose metabolism is essential for NK cell functional responses N Assmann, KL O'Brien, RP Donnelly, L Dyck, V Zaiatz-Bittencourt, RM Loftus, P Heinrich, PJ Oefner, L Lynch, CM Gardiner, K Dettmer, DK Finlay	Nature Immunology	2017
PCSK9 signaling pathways and their potential importance in clinical practice M Wiciński, J Żak, B Malinowski, G Popek, G Grześk	The EPMA Journal	2017
Stigmasterol prevents glucolipotoxicity induced defects in glucose-stimulated insulin secretion MG Ward, G Li, VC Barbosa-Lorenzi, M Hao	Scientific Reports	2017
The selective peroxisome proliferator-activated receptor-delta agonist seladelpar reverses nonalcoholic steatohepatitis pathology by abrogating lipotoxicity in diabetic obese mice F Haczeyni, H Wang, V Barn, AR Mridha, MM Yeh, WG Haigh, GN Ioannou, YJ Choi, CA McWherter, NC Teoh, GC Farrell	Hepatology Communications	2017
Green tea polyphenol treatment attenuates atherosclerosis in high-fat diet-fed apolipoprotein E-knockout mice via alleviating dyslipidemia and up-regulating autophagy S Ding, J Jiang, P Yu, G Zhang, G Zhang, X Liu, M Bader	PloS one	2017
Nischarin inhibition alters energy metabolism by activating AMP-activated protein kinase S Dong, S Baranwal, A Garcia, SJ Serrano-Gomez, S Eastlack, T Iwakuma, D Mercante, F Mauvais-Jarvis, SK Alahari	The Journal of biological chemistry	2017
Protective Effect of Argan and Olive Oils against LPS-Induced Oxidative Stress and Inflammation in Mice Livers SE Kamouni, RE Kebbaj, P Andreoletti, AE Ktaibi, I Rharrassi, A Essamadi, ME Kebbaj, S Mandard, N Latruffe, J Vamecq, B Nasser, M Cherkaoui-Malki	International journal of molecular sciences	2017
Inhibition of cholesterol biosynthesis through RNF145-dependent ubiquitination of SCAP L Zhang, P Rajbhandari, C Priest, J Sandhu, X Wu, R Temel, A Castrillo, TQ de Vallim, T Sallam, P Tontonoz	eLife	2017
Betaine attenuates chronic alcohol‑induced fatty liver by broadly regulating hepatic lipid metabolism W Yang, L Huang, J Gao, S Wen, Y Tai, M Chen, Z Huang, R Liu, C Tang, J Li	Molecular medicine reports	2017
Actinidia chinensis Planch root extract inhibits cholesterol metabolism in hepatocellular carcinoma through upregulation of PCSK9 M He, J Hou, L Wang, M Zheng, T Fang, X Wang, J Xia	Oncotarget	2017
An Essential Role for the Tumor-Suppressor Merlin in Regulating Fatty Acid Synthesis DS Stepanova, G Semenova, YM Kuo, AJ Andrews, S Ammoun, CO Hanemann, J Chernoff	Cancer research	2017
Role of transgelin-2 in diabetes-associated pancreatic ductal adenocarcinoma Y Sun, W He, M Luo, Y Zhou, G Chang, W Ren, K Wu, X Li, J Shen, X Zhao, Y Hu	Oncotarget	2017
Skin-specific regulation of SREBP processing and lipid biosynthesis by glycerol kinase 5 D Zhang, W Tomisato, L Su, L Sun, JH Choi, Z Zhang, K Wang, X Zhan, M Choi, X Li, M Tang, JM Castro-Perez, S Hildebrand, AR Murray, EM Moresco, B Beutler	Proceedings of the National Academy of Sciences	2017
STARD3 mediates endoplasmic reticulum‐to‐endosome cholesterol transport at membrane contact sites LP Wilhelm, C Wendling, B Védie, T Kobayashi, MP Chenard, C Tomasetto, G Drin, F Alpy	The EMBO Journal	2017
Degradation of PHLPP2 by KCTD17, via a Glucagon-dependent Pathway, Promotes Hepatic Steatosis KJ Kim, D Ryu, P Dongiovanni, L Ozcan, S Nayak, B Ueberheide, L Valenti, J Auwerx, UB Pajvani	Gastroenterology	2017
Lipid metabolism fattens up hedgehog signaling R Blassberg, J Jacob	BMC Biology	2017
Transcriptional and post-translational changes in the brain of mice deficient in cholesterol removal mediated by cytochrome P450 46A1 (CYP46A1) N Mast, JB Lin, KW Anderson, I Bjorkhem, IA Pikuleva, JM Lobaccaro	PloS one	2017
Lunasin functionally enhances LDL uptake via inhibiting PCSK9 and enhancing LDLR expression in vitro and in vivo L Gu, Y Wang, Y Xu, Q Tian, G Lei, C Zhao, Z Gao, Q Pan, W Zhao, L Nong, S Tan	Oncotarget	2017
Endoplasmic reticulum stress inhibits expression of genes involved in thyroid hormone synthesis and their key transcriptional regulators in FRTL-5 thyrocytes G Wen, R Ringseis, K Eder, DY Jin	PloS one	2017
Palmitic Acid: Physiological Role, Metabolism and Nutritional Implications G Carta, E Murru, S Banni, C Manca	Frontiers in physiology	2017
Generation of patient specific human neural stem cells from Niemann-Pick disease type C patient-derived fibroblasts EA Sung, KR Yu, JH Shin, Y Seo, HS Kim, MG Koog, I Kang, JJ Kim, BC Lee, TH Shin, JY Lee, S Lee, TW Kang, SW Choi, KS Kang	Oncotarget	2017
Transcriptional Regulation of T-Cell Lipid Metabolism: Implications for Plasma Membrane Lipid Rafts and T-Cell Function GA Robinson, KE Waddington, I Pineda-Torra, EC Jury	Frontiers in immunology	2017
Systems Pharmacology Dissection of Cholesterol Regulation Reveals Determinants of Large Pharmacodynamic Variability between Cell Lines P Blattmann, D Henriques, M Zimmermann, F Frommelt, U Sauer, J Saez-Rodriguez, R Aebersold	Cell Systems	2017
Increased 27-hydroxycholesterol production during luteolysis may mediate the progressive decline in progesterone secretion Y Xu, SM Hutchison, JJ Hernández-Ledezma, RL Bogan	Molecular Human Reproduction	2017
Zinc mediates the SREBP-SCD axis to regulate lipid metabolism in Caenorhabditis elegans JJ Zhang, JJ Hao, YR Zhang, YL Wang, MY Li, HL Miao, XJ Zou, B Liang	Journal of lipid research	2017
Lipid Metabolism and Lipid Droplets in Pancreatic Cancer and Stellate Cells Y Sunami, A Rebelo, J Kleeff	Cancers	2017
Leonurus japonicus Houtt Attenuates Nonalcoholic Fatty Liver Disease in Free Fatty Acid-Induced HepG2 Cells and Mice Fed a High-Fat Diet MR Lee, K Park, J Ma	Nutrients	2017
Hepatocyte-specific deletion of BAP31 promotes SREBP1C activation, promotes hepatic lipid accumulation, and worsens IR in mice JL Xu, LY Li, YQ Wang, YQ Li, M Shan, SZ Sun, Y Yu, B Wang	Journal of lipid research	2017
SREBP-2-driven transcriptional activation of human SND1 oncogene S Armengol, E Arretxe, L Enzunza, I Llorente, U Mendibil, H Navarro-Imaz, B Ochoa, Y Chico, MJ MartEDnez	Oncotarget	2017
The hepatic circadian clock fine-tunes the lipogenic response to feeding through RORα/γ Y Zhang, R Papazyan, M Damle, B Fang, J Jager, D Feng, LC Peed, D Guan, Z Sun, MA Lazar	Genes & development	2017
Fatty acids promote fatty liver disease via the dysregulation of 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway M Li, C Xu, J Shi, J Ding, X Wan, D Chen, J Gao, C Li, J Zhang, Y Lin, Z Tu, X Kong, Y Li, C Yu	Gut	2017
Control of Muscle Metabolism by the Mediator Complex L Amoasii, EN Olson, R Bassel-Duby	Cold Spring Harbor Perspectives in Medicine	2017
Pak1 mediates the stimulatory effect of insulin and curcumin on hepatic ChREBP expression K Zeng, L Tian, A Sirek, W Shao, L Liu, YT Chiang, J Chernoff, DS Ng, J Weng, T Jin, F Liu	Journal of Molecular Cell Biology	2017
Aβ inhibits SREBP-2 activation through Akt inhibition A Mohamed, A Viveiros, K Williams, EP de Chaves	Journal of lipid research	2017
Coronary Artery Disease–Associated LIPA Coding Variant rs1051338 Reduces Lysosomal Acid Lipase Levels and Activity in Lysosomes GE Morris, PS Braund, JS Moore, NJ Samani, V Codd, TR Webb	Arteriosclerosis, thrombosis, and vascular biology	2017
Haploid Mammalian Genetic Screen Identifies UBXD8 as a Key Determinant of HMGCR Degradation and Cholesterol Biosynthesis A Loregger, M Raaben, J Tan, S Scheij, M Moeton, M van den Berg, H Gelberg-Etel, E Stickel, J Roitelman, T Brummelkamp, N Zelcer	Arteriosclerosis, thrombosis, and vascular biology	2017
Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling G Lee, Y Zheng, S Cho, C Jang, C England, JM Dempsey, Y Yu, X Liu, L He, PM Cavaliere, A Chavez, E Zhang, M Isik, A Couvillon, NE Dephoure, TK Blackwell, JJ Yu, JD Rabinowitz, LC Cantley, J Blenis	Cell	2017
Artesunate Activates the Intrinsic Apoptosis of HCT116 Cells through the Suppression of Fatty Acid Synthesis and the NF-κB Pathway X Chen, Y Wong, T Lim, W Lim, Q Lin, J Wang, Z Hua	Molecules (Basel, Switzerland)	2017
TIP30 regulates lipid metabolism in hepatocellular carcinoma by regulating SREBP1 through the Akt/mTOR signaling pathway F Yin, G Sharen, F Yuan, Y Peng, R Chen, X Zhou, H Wei, B Li, W Jing, J Zhao	Oncogenesis	2017
A novel role of astrocyte elevated gene-1 (AEG-1) in regulating nonalcoholic steatohepatitis (NASH): Srivastava, Robertson, et al J Srivastava, CL Robertson, K Ebeid, M Dozmorov, D Rajasekaran, R Mendoza, A Siddiq, MA Akiel, N Jariwala, XN Shen, JJ Windle, MA Subler, ND Mukhopadhyay, S Giashuddin, S Ghosh, Z Lai, Y Chen, PB Fisher, AK Salem, AJ Sanyal, D Sarkar	Hepatology	2017
Does Sirt2 Regulate Cholesterol Biosynthesis During Oligodendroglial Differentiation In Vitro and In Vivo? Thangaraj MP, Furber KL, Sobchishin L, Ji S, Doucette JR, Nazarali AJ	Cellular and Molecular Neurobiology	2017
Transcriptome analysis of the pectoral muscles of local chickens and commercial broilers using Ribo-Zero ribonucleic acid sequencing. Zhang Y, Li D, Han R, Wang Y, Li G, Liu X, Tian Y, Kang X, Li Z	PloS one	2017
Flavonoid-Rich Extract of Paulownia fortunei Flowers Attenuates Diet-Induced Hyperlipidemia, Hepatic Steatosis and Insulin Resistance in Obesity Mice by AMPK Pathway. Liu C, Ma J, Sun J, Cheng C, Feng Z, Jiang H, Yang W	Nutrients	2017
Overexpression of Insig-2 inhibits atypical antipsychotic-induced adipogenic differentiation and lipid biosynthesis in adipose-derived stem cells. Chen CC, Hsu LW, Huang KT, Goto S, Chen CL, Nakano T	Scientific Reports	2017
Dietary Fatty Acid Composition Modulates Obesity and Interacts with Obesity-Related Genes. Hammad SS, Jones PJ	Lipids	2017
Effects of ingredients of Korean brown rice cookies on attenuation of cholesterol level and oxidative stress in high-fat diet-fed mice. Hong SH, Kim M, Woo M, Song YO	Nutrition Research and Practice	2017
Proteostatic Tactics in the Strategy of Sterol Regulation. Wangeline MA, Vashistha N, Hampton RY	Annual Review of Cell and Developmental Biology	2017
The MicroRNA Interaction Network of Lipid Diseases. Kandhro AH, Shoombuatong W, Nantasenamat C, Prachayasittikul V, Nuchnoi P	Frontiers in Genetics	2017
The influence of metabolic imbalances and oxidative stress on the outcome of critically ill polytrauma patients: a review Rogobete AF, Sandesc D, Papurica M, Stoicescu ER, Popovici SE, Bratu LM, Vernic C, Sas AM, Stan AT, Bedreag OH	Burns & Trauma	2017
Statin prescribing for people with severe mental illnesses: a staggered cohort study of ‘real-world’ impacts Blackburn R, Osborn D, Walters K, Falcaro M, Nazareth I, Petersen I	BMJ Open	2017
Drosophila TRF2 and TAF9 regulate lipid droplet size and phospholipid fatty acid composition Fan W, Lam SM, Xin J, Yang X, Liu Z, Liu Y, Wang Y, Shui G, Huang X	PLoS genetics	2017
Identification of a novel human long non-coding RNA that regulates hepatic lipid metabolism by inhibiting SREBP-1c Li D, Cheng M, Niu Y, Chi X, Liu X, Fan J, Fan H, Chang Y, Yang W	International journal of biological sciences	2017
Obesity: Rubensian beauty turned into major health problem Vari SG	Croatian medical journal	2017
A relative quantitative positive/negative ion switching method for untargeted lipidomics via high resolution LC-MS/MS from any biological source Breitkopf SB, Ricoult SJ, Yuan M, Xu Y, Peake DA, Manning BD, Asara JM	Metabolomics : Official journal of the Metabolomic Society	2017
Functional characterization and differential nutritional regulation of putative Elovl5 and Elovl4 elongases in large yellow croaker (Larimichthys crocea) Li S, Monroig Ó, Wang T, Yuan Y, Carlos Navarro J, Hontoria F, Liao K, Tocher DR, Mai K, Xu W, Ai Q	Scientific Reports	2017
GSK-3–mediated phosphorylation couples ER–Golgi transport and nuclear stabilization of the CREB-H transcription factor to mediate apolipoprotein secretion Barbosa S, Carreira S, O\u2019Hare P	Molecular biology of the cell	2017
Lipid quantification by Raman microspectroscopy as a potential biomarker in prostate cancer O\u2019Malley J, Kumar R, Kuzmin A, Pliss A, Yadav N, Balachandar S, Wang J, Attwood K, Prasad PN, Chandra D	Cancer Letters	2017
Mutant p53 Protein and the Hippo Transducers YAP and TAZ: A Critical Oncogenic Node in Human Cancers Ferraiuolo M, Verduci L, Blandino G, Strano S	International journal of molecular sciences	2017
microRNA-29 mediates a novel negative feedback loop to regulate SCAP/SREBP-1 and lipid metabolism Ru P, Guo D		2017
Saturated Fatty Acids and Cardiovascular Disease: Replacements for Saturated Fat to Reduce Cardiovascular Risk Briggs MA, Petersen KS, Kris-Etherton PM	Healthcare	2017
Metabolomics study of the therapeutic mechanism of Schisandra Chinensis lignans in diet-induced hyperlipidemia mice Sun JH, Liu X, Cong LX, Li H, Zhang CY, Chen JG, Wang CM	Lipids in Health and Disease	2017
Prenatal caloric restriction alters lipid metabolism but not hepatic Fasn gene expression and methylation profiles in rats Nowacka-Woszuk J, Madeja ZE, Chmurzynska A	BMC genetics	2017
A novel role for CRTC2 in hepatic cholesterol synthesis through SREBP‐2 Li Y, Song Y, Zhao M, Guo Y, Yu C, Chen W, Shao S, Xu C, Zhou X, Zhao L, Zhang Z, Bo T, Xia Y, Proud CG, Wang X, Wang L, Zhao J, Gao L	Hepatology	2017
Individual co-variation between viral RNA load and gene expression reveals novel host factors during early dengue virus infection of the Aedes aegypti midgut Raquin V, Merkling SH, Gausson V, Moltini-Conclois I, Frangeul L, Varet H, Dillies MA, Saleh MC, Lambrechts L	PLoS neglected tropical diseases	2017
Exenatide induces carcinoembryonic antigen‐related cell adhesion molecule 1 expression to prevent hepatic steatosis Ghadieh HE, Muturi HT, Russo L, Marino CC, Ghanem SS, Khuder SS, Hanna JC, Jash S, Puri V, Heinrich G, Gatto\u2010Weis C, Lee KY, Najjar SM	Hepatology Communications	2017
Interlink between cholesterol & cell cycle in prostate carcinoma Singh G, Sankanagoudar S, Dogra P, Chandra NC	The Indian journal of medical research	2017
Exenatide Prevents Diet-induced Hepatocellular Injury in A CEACAM1-Dependent Mechanism. Ghadieh HE, Muturi HT, Najjar SM	Journal of diabetes and treatment	2017
Inhibition of exendin-4-induced steatosis by protein kinase A in cultured HepG2 human hepatoma cells. Chen-Liaw AY, Hammel G, Gomez G	In vitro cellular & developmental biology. Animal	2017
Recent insights into the implications of metabolism in plasmacytoid dendritic cell innate functions: Potential ways to control these functions Saas P, Varin A, Perruche S, Ceroi A	F1000Research	2017
Roles of Thyroid Transcription Factor 1 in Lung Cancer Biology. Phelps CA, Lai SC, Mu D	Vitamins and hormones	2017
ChREBP Regulates Fructose-Induced Glucose Production Independently of Insulin Signaling Mi-sung Kim, Sarah Krawczyk, Ludivine Doridot, Alan J. Fowler, Jennifer Wang, Sunia Trauger, Hye-Lim Noh, Hee Joon Kang, John Meissen, Matthew Blatnik, Jason Kim, Michelle Lai, Mark Herman	Journal of Clinical Investigation	2016
Fundamentals of cancer metabolism RJ DeBerardinis, NS Chandel	Science Advances	2016
The role of bile acids in metabolic regulation L Vítek, M Haluzík	Journal of Endocrinology	2016
MicroRNA regulation of macrophages in human pathologies Y Wei, A Schober	Cellular and Molecular Life Sciences	2016
microRNAs in lipoprotein metabolism and cardiometabolic disorders N Rotllan, N Price, P Pati, L Goedeke, C Fernández-Hernando	Atherosclerosis	2016
miRNAs and High-Density Lipoprotein metabolism Á Baldán, TQ de Vallim	Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids	2016
Micro-RNAs and High-Density Lipoprotein MetabolismHighlights A Canfrán-Duque, CS Lin, L Goedeke, Y Suárez, C Fernández-Hernando	Arteriosclerosis, thrombosis, and vascular biology	2016
Truths and controversies concerning the role of miRNAs in atherosclerosis and lipid metabolism: Á Baldán, C Fernández-Hernando	Current Opinion in Lipidology	2016
Fibroblast growth factor 21 potentially inhibits microRNA-33 expression to affect macrophage actions Y Guo, F Luo, Y Yi, D Xu	Lipids in Health and Disease	2016
Lipodystrophy and severe metabolic dysfunction in mice with adipose tissue-specific insulin receptor ablation G Qiang, HW Kong, S Xu, HA Pham, SD Parlee, AA Burr, V Gil, J Pang, A Hughes, X Gu, G Fantuzzi, OA MacDougald, CW Liew	Molecular Metabolism	2016
Berberine prevents progression from hepatic steatosis to steatohepatitis and fibrosis by reducing endoplasmic reticulum stress Z Zhang, B Li, X Meng, S Yao, L Jin, J Yang, J Wang, H Zhang, Z Zhang, D Cai, Y Zhang, G Ning	Scientific Reports	2016
Hepatoprotective Effect and Synergism of Bisdemethoycurcumin against MCD Diet-Induced Nonalcoholic Fatty Liver Disease in Mice SB Kim, OH Kang, YS Lee, SH Han, YS Ahn, SW Cha, YS Seo, R Kong, DY Kwon, GL Volti	PloS one	2016
Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production PM Titchenell, WJ Quinn, M Lu, Q Chu, W Lu, C Li, H Chen, BR Monks, J Chen, JD Rabinowitz, MJ Birnbaum	Cell Metabolism	2016
Feedback modulation of cholesterol metabolism by the lipid-responsive non-coding RNA LeXis T Sallam, MC Jones, T Gilliland, L Zhang, X Wu, A Eskin, J Sandhu, D Casero, TQ de Vallim, C Hong, M Katz, R Lee, J Whitelegge, P Tontonoz	Nature	2016
Regulation of PXR and CAR by protein-protein interaction and signaling crosstalk P Oladimeji, H Cui, C Zhang, T Chen	Expert Opinion on Drug Metabolism & Toxicology	2016
Pleiotropic effects of statins: new therapeutic targets in drug design O Bedi, V Dhawan, PL Sharma, P Kumar	Naunyn-Schmiedeberg's Archives of Pharmacology	2016
Targeting arginase-II protects mice from high-fat-diet-induced hepatic steatosis through suppression of macrophage inflammation C Liu, AG Rajapakse, E Riedo, B Fellay, MC Bernhard, JP Montani, Z Yang, XF Ming	Scientific Reports	2016
Berberine Alleviates Olanzapine-Induced Adipogenesis via the AMPKα–SREBP Pathway in 3T3-L1 Cells Y Li, X Zhao, X Feng, X Liu, C Deng, CH Hu	International journal of molecular sciences	2016
Mangiferin modulation of metabolism and metabolic syndrome: Metabolism and Metabolic Syndrome EV Fomenko, Y Chi	BioFactors	2016
Simvastatin promotes NPC1-mediated free cholesterol efflux from lysosomes through CYP7A1/LXRα signalling pathway in oxLDL-loaded macrophages X Xu, A Zhang, MS Halquist, X Yuan, SC Henderson, WL Dewey, PL Li, N Li, F Zhang	Journal of Cellular and Molecular Medicine	2016
O-GlcNAcylation and the Metabolic Shift in High-Proliferating Cells: All the Evidence Suggests that Sugars Dictate the Flux of Lipid Biogenesis in Tumor Processes SF Baldini, T Lefebvre	Frontiers in Oncology	2016
Cholesterol-Independent SREBP-1 Maturation Is Linked to ARF1 Inactivation LJ Smulan, W Ding, E Freinkman, S Gujja, YJ Edwards, AK Walker	Cell Reports	2016
Acyl CoA synthetase 5 (ACSL5) ablation in mice increases energy expenditure and insulin sensitivity and delays fat absorption TA Bowman, KR O'Keeffe, T D'Aquila, QW Yan, JD Griffin, EA Killion, DM Salter, DG Mashek, KK Buhman, AS Greenberg	Molecular Metabolism	2016
Long-term exposure to abnormal glucose levels alters drug metabolism pathways and insulin sensitivity in primary human hepatocytes MD Davidson, KR Ballinger, SR Khetani	Scientific Reports	2016
Progress and prospects of long noncoding RNAs in lipid homeostasis Z Chen	Molecular Metabolism	2016
Neuronal Activity-Induced Sterol Regulatory Element Binding Protein-1 (SREBP1) is Disrupted in Dysbindin-Null Mice—Potential Link to Cognitive Impairment in Schizophrenia Y Chen, S Bang, MF McMullen, H Kazi, K Talbot, MX Ho, G Carlson, SE Arnold, WY Ong, SF Kim	Molecular Neurobiology	2016
CREBH-FGF21 axis improves hepatic steatosis by suppressing adipose tissue lipolysis JG Park, X Xu, S Cho, KY Hur, MS Lee, S Kersten, AH Lee	Scientific Reports	2016
Pharmacology of bile acid receptors: Evolution of bile acids from simple detergents to complex signaling molecules BL Copple, T Li	Pharmacological Research	2016
Regulation of glucose metabolism from a liver-centric perspective HS Han, G Kang, JS Kim, BH Choi, SH Koo	Experimental & molecular medicine	2016
Aβ-Induced Insulin Resistance and the Effects of Insulin on the Cholesterol Synthesis Pathway and Aβ Secretion in Neural Cells D Najem, M Bamji-Mirza, Z Yang, W Zhang	Neuroscience Bulletin	2016
Minor lipid metabolic perturbations in the liver of Atlantic salmon (Salmo salar L.) caused by suboptimal dietary content of nutrients from fish oil M Sanden, NS Liland, Ø Sæle, G Rosenlund, S Du, BE Torstensen, I Stubhaug, B Ruyter, NH Sissener	Fish Physiology and Biochemistry	2016
Clinical Significance of Determining Plasma MicroRNA33b in Type 2 Diabetic Patients with Dyslipidemia Y Kimura, N Tamasawa, K Matsumura, H Murakami, M Yamashita, K Matsuki, J Tanabe, H Murakami, J Matsui, M Daimon	Journal of Atherosclerosis and Thrombosis	2016
Fibroblast Growth Factor 21 Protects against Atherosclerosis via Fine-Tuning the Multiorgan Crosstalk L Jin, Z Lin, A Xu	Diabetes & Metabolism Journal	2016
Hepatoprotective Effects of Chinese Medicinal Herbs: A Focus on Anti-Inflammatory and Anti-Oxidative Activities P Lam, F Cheung, H Tan, N Wang, M Yuen, Y Feng	International journal of molecular sciences	2016
MicroRNAs in brain cholesterol metabolism and their implications for Alzheimer's disease H Yoon, LF Flores, J Kim	Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids	2016
Suppressive Effects of the Site 1 Protease (S1P) Inhibitor, PF-429242, on Dengue Virus Propagation L Uchida, S Urata, G Ulanday, Y Takamatsu, J Yasuda, K Morita, D Hayasaka	Viruses	2016
Transcriptome profiling unveils the role of cholesterol in IL-17A signaling in psoriasis P Varshney, A Narasimhan, S Mittal, G Malik, K Sardana, N Saini	Scientific Reports	2016
Preventing High Fat Diet-induced Obesity and Improving Insulin Sensitivity through Neuregulin 4 Gene Transfer Y Ma, M Gao, D Liu	Scientific Reports	2016
Hyperlipidemia-associated gene variations and expression patterns revealed by whole-genome and transcriptome sequencing of rabbit models Z Wang, J Zhang, H Li, J Li, M Niimi, G Ding, H Chen, J Xu, H Zhang, Z Xu, Y Dai, T Gui, S Li, Z Liu, S Wu, M Cao, L Zhou, X Lu, J Wang, J Yang, Y Fu, D Yang, J Song, T Zhu, S Li, B Ning, Z Wang, T Koike, M Shiomi, E Liu, L Chen, J Fan, YE Chen, Y Li	Scientific Reports	2016
Role of BAF60a/BAF60c in chromatin remodeling and hepatic lipid metabolism P Zhang, L Li, Z Bao, F Huang	Nutrition & Metabolism	2016
E4BP4 is an insulin-induced stabilizer of nuclear SREBP-1c and promotes SREBP-1c-mediated lipogenesis X Tong, P Li, D Zhang, K VanDommelen, N Gupta, L Rui, MB Omary, L Yin	Journal of lipid research	2016
Contribution of Accelerated Degradation to Feedback Regulation of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase and Cholesterol Metabolism in the Liver S Hwang, IZ Hartman, LN Calhoun, K Garland, GA Young, MA Mitsche, J McDonald, F Xu, L Engelking, RA DeBose-Boyd	The Journal of biological chemistry	2016
Liver MicroRNA-291b-3p Promotes Hepatic Lipogenesis through Negative Regulation of Adenosine 5′-Monophosphate (AMP)-activated Protein Kinase α1 X Meng, J Guo, W Fang, L Dou, M Li, X Huang, S Zhou, Y Man, W Tang, L Yu, J Li	The Journal of biological chemistry	2016
Loss of Fas apoptosis inhibitory molecule leads to spontaneous obesity and hepatosteatosis J Huo, Y Ma, JJ Liu, YS Ho, S Liu, LY Soh, S Chen, S Xu, W Han, A Hong, SC Lim, KP Lam	Cell Death and Disease	2016
The phosphorylation-dependent regulation of nuclear SREBP1 during mitosis links lipid metabolism and cell growth MT Bengoechea-Alonso, J Ericsson	Cell cycle (Georgetown, Tex.)	2016
Association study between metabolic syndrome and rs8066560 polymorphism in the promoter region of sterol regulatory element-binding transcription factor 1 gene in Iranian children and adolescents H Miranzadeh-Mahabadi, M Emadi-Baygi, P Nikpour, R Kelishadi	International journal of preventive medicine	2016
Camphene, a Plant Derived Monoterpene, Exerts Its Hypolipidemic Action by Affecting SREBP-1 and MTP Expression I Vallianou, M Hadzopoulou-Cladaras, P Aspichueta	PloS one	2016
Reduced sterol regulatory element-binding protein (SREBP) processing through site-1 protease (S1P) inhibition alters oligodendrocyte differentiation in vitro H Monnerie, M Romer, BK Jensen, JS Millar, KL Jordan-Sciutto, SF Kim, JB Grinspan	Journal of Neurochemistry	2016
The effects of prenatal metformin on obesogenic diet-induced alterations in maternal and fetal fatty acid metabolism K Harris, N Desai, M Gupta, X Xue, PK Chatterjee, B Rochelson, CN Metz	Nutrition & Metabolism	2016
TAK1 regulates hepatic lipid homeostasis through SREBP S Morioka, K Sai, E Omori, Y Ikeda, K Matsumoto, J Ninomiya-Tsuji	Oncogene	2016
SREBP-1c/MicroRNA 33b Genomic Loci Control Adipocyte Differentiation NL Price, B Holtrup, SL Kwei, M Wabitsch, M Rodeheffer, L Bianchini, Y Suárez, C Fernández-Hernando	Molecular and cellular biology	2016
Feedback Loop Regulation of SCAP/SREBP-1 by miR-29 Modulates EGFR Signaling-Driven Glioblastoma Growth P Ru, P Hu, F Geng, X Mo, C Cheng, JY Yoo, X Cheng, X Wu, JY Guo, I Nakano, E Lefai, B Kaur, A Chakravarti, D Guo	Cell Reports	2016
Inhibition of SOAT1 Suppresses Glioblastoma Growth via Blocking SREBP-1-Mediated Lipogenesis F Geng, X Cheng, X Wu, JY Yoo, C Cheng, JY Guo, X Mo, P Ru, B Hurwitz, SH Kim, J Otero, V Puduvalli, E Lefai, J Ma, I Nakano, C Horbinski, B Kaur, A Chakravarti, D Guo	Clinical cancer research	2016
Dysregulation of the Low-Density Lipoprotein Receptor Pathway Is Involved in Lipid Disorder-Mediated Organ Injury Y Zhang, KL Ma, XZ Ruan, BC Liu	International journal of biological sciences	2016
The Hippo pathway, p53 and cholesterol Y Aylon, M Oren	Cell cycle (Georgetown, Tex.)	2016
Lack of association between SREBF-1c gene polymorphisms and risk of non-alcoholic fatty liver disease in a Chinese Han population XE Peng, FL Chen, W Liu, ZJ Hu, X Lin	Scientific Reports	2016
Fatty liver formation in fulminant type 1 diabetes T Matsuo, Y Ushiroda	Endocrinology, diabetes & metabolism case reports	2016
Replacement of Marine Fish Oil with de novo Omega-3 Oils from Transgenic Camelina sativa in Feeds for Gilthead Sea Bream (Sparus aurata L.) MB Betancor, M Sprague, D Montero, S Usher, O Sayanova, PJ Campbell, JA Napier, MJ Caballero, M Izquierdo, DR Tocher	Lipids	2016
Is REDD1 a Metabolic Éminence Grise? C Lipina, HS Hundal	Trends in Endocrinology & Metabolism	2016
Glucagon regulates hepatic lipid metabolism via cAMP and Insig-2 signaling: implication for the pathogenesis of hypertriglyceridemia and hepatic steatosis H Wang, M Zhao, N Sud, P Christian, J Shen, Y Song, A Pashaj, K Zhang, T Carr, Q Su	Scientific Reports	2016
The miR-33 gene is identified in a marine teleost: a potential role in regulation of LC-PUFA biosynthesis in Siganus canaliculatus Q Zhang, C You, S Wang, Y Dong, Ó Monroig, DR Tocher, Y Li	Scientific Reports	2016
Novel role for the CRTC2 in lipid homeostasis T Matsuzaka, H Shimano	Journal of Diabetes Investigation	2016
Beneficial Effect of Synbiotic Supplementation on Hepatic Steatosis and Anthropometric Parameters, But Not on Gut Permeability in a Population with Nonalcoholic Steatohepatitis S Ferolla, C Couto, L Costa-Silva, G Armiliato, C Pereira, F Martins, M Ferrari, E Vilela, H Torres, A Cunha, T Ferrari	Nutrients	2016
Bisphenol A Exposure May Induce Hepatic Lipid Accumulation via Reprogramming the DNA Methylation Patterns of Genes Involved in Lipid Metabolism ZH Ke, JX Pan, LY Jin, HY Xu, TT Yu, K Ullah, TU Rahman, J Ren, Y Cheng, XY Dong, JZ Sheng, HF Huang	Scientific Reports	2016
A Novel Link between Plasma MicroRNA-33b Levels and Lipid Disorders in Diabetes Mellitus K Ono	Journal of Atherosclerosis and Thrombosis	2016
Endoplasmic Reticulum–Associated Degradation and Lipid Homeostasis J Stevenson, EY Huang, JA Olzmann	Annual Review of Nutrition	2016
Microarray analysis of gene expression in liver, adipose tissue and skeletal muscle in response to chronic dietary administration of NDGA to high-fructose fed dyslipidemic rats H Zhang, WJ Shen, Y Li, A Bittner, S Bittner, J Tabassum, YF Cortez, FB Kraemer, S Azhar	Nutrition & Metabolism	2016
miRNAs in non-alcoholic fatty liver disease Z He, C Hu, W Jia	Frontiers of Medicine	2016
Cloning and Characterization of Lxr and Srebp1, and Their Potential Roles in Regulation of LC-PUFA Biosynthesis in Rabbitfish Siganus canaliculatus Q Zhang, C You, F Liu, W Zhu, S Wang, D Xie, Ó Monroig, DR Tocher, Y Li	Lipids	2016
Integrative Transcriptome Analyses of Metabolic Responses in Mice Define Pivotal LncRNA Metabolic Regulators L Yang, P Li, W Yang, X Ruan, K Kiesewetter, J Zhu, H Cao	Cell Metabolism	2016
Role of MSX1 in Osteogenic Differentiation of Human Dental Pulp Stem Cells N Goto, K Fujimoto, S Fujii, H Ida-Yonemochi, H Ohshima, T Kawamoto, M Noshiro, C Shukunami, K Kozai, Y Kato	Stem Cells International	2016
Açai ( Euterpe oleracea Mart.) Upregulates Paraoxonase 1 Gene Expression and Activity with Concomitant Reduction of Hepatic Steatosis in High-Fat Diet-Fed Rats RR Pereira, IC de Abreu, JF da Guerra, NN Lage, JM Lopes, M Silva, WG de Lima, ME Silva, ML Pedrosa	Oxidative medicine and cellular longevity	2016
Cholesterol metabolism in cholestatic liver disease and liver transplantation: From molecular mechanisms to clinical implications K Nemes, F Åberg, H Gylling, H Isoniemi	World journal of hepatology	2016
Transcriptome Analysis Reveals Regulation of Gene Expression for Lipid Catabolism in Young Broilers by Butyrate Glycerides F Yin, H Yu, D Lepp, X Shi, X Yang, J Hu, S Leeson, C Yang, S Nie, Y Hou, J Gong, MJ Virolle	PloS one	2016
Statin Effects to Reduce Hepatosteatosis as Measured by Computed Tomography in Patients With Human Immunodeficiency Virus J Lo, MT Lu, EA Kim, E Nou, TR Hallett, J Park, U Hoffmann, SK Grinspoon	Open Forum Infectious Diseases	2016
Insulin induction of SREBP-1c in rodent liver requires LXRα-C/EBPβ complex J Tian, JL Goldstein, MS Brown	Proceedings of the National Academy of Sciences	2016
Mimp/Mtch2, an Obesity Susceptibility Gene, Induces Alteration of Fatty Acid Metabolism in Transgenic Mice Y Bar-Lev, S Moshitch-Moshkovitz, G Tsarfaty, D Kaufman, J Horev, JH Resau, I Tsarfaty, GW Wong	PloS one	2016
Sterol Regulatory Element Binding Protein Regulates the Expression and Metabolic Functions of Wild-Type and Oncogenic IDH1 SJ Ricoult, CC Dibble, JM Asara, BD Manning	Molecular and cellular biology	2016
Obese diet-induced mouse models of nonalcoholic steatohepatitis-tracking disease by liver biopsy MN Kristiansen, SS Veidal, KT Rigbolt, KS Tølbøl, JD Roth, J Jelsing, N Vrang, M Feigh	World journal of hepatology	2016
Fatostatin blocks ER exit of SCAP but inhibits cell growth in a SCAP-independent manner WS 邵威, CE Machamer, PJ Espenshade	Journal of lipid research	2016
Differential Regulation of Gene Expression by Cholesterol Biosynthesis Inhibitors That Reduce (Pravastatin) or Enhance (Squalestatin 1) Nonsterol Isoprenoid Levels in Primary Cultured Mouse and Rat Hepatocytes EA Rondini, Z Duniec-Dmuchowski, D Cukovic, AA Dombkowski, TA Kocarek	The Journal of pharmacology and experimental therapeutics	2016
Dysregulated signaling hubs of liver lipid metabolism reveal hepatocellular carcinoma pathogenesis S Lee, A Mardinoglu, C Zhang, D Lee, J Nielsen	Nucleic Acids Research	2016
GPR40 agonist ameliorates liver X receptor-induced lipid accumulation in liver by activating AMPK pathway M Li, X Meng, J Xu, X Huang, H Li, G Li, S Wang, Y Man, W Tang, J Li	Scientific Reports	2016
Current trends in oxysterol research WJ Griffiths, J Abdel-Khalik, T Hearn, E Yutuc, AH Morgan, Y Wang	Biochemical Society Transactions	2016
Direct Demonstration That Loop1 of Scap Binds to Loop7: A CRUCIAL EVENT IN CHOLESTEROL HOMEOSTASIS Y Zhang, KM Lee, LN Kinch, L Clark, NV Grishin, DM Rosenbaum, MS Brown, JL Goldstein, A Radhakrishnan	The Journal of biological chemistry	2016
Impact of ACTH Signaling on Transcriptional Regulation of Steroidogenic Genes C Ruggiero, E Lalli	Frontiers in Endocrinology	2016
Transcriptome Remodeling in Trypanosoma cruzi and Human Cells during Intracellular Infection Y Li, S Shah-Simpson, K Okrah, AT Belew, J Choi, KL Caradonna, P Padmanabhan, DM Ndegwa, MR Temanni, HC Bravo, NM El-Sayed, BA Burleigh, C Clayton	PLoS pathogens	2016
The LATS2 tumor suppressor inhibits SREBP and suppresses hepatic cholesterol accumulation Y Aylon, A Gershoni, R Rotkopf, IE Biton, Z Porat, AP Koh, X Sun, Y Lee, MI Fiel, Y Hoshida, SL Friedman, RL Johnson, M Oren	Genes & development	2016
Molecular Cloning, Functional Characterization and Nutritional Regulation of the Putative Elongase Elovl5 in the Orange-Spotted Grouper (Epinephelus coioides) S Li, Y Yuan, T Wang, W Xu, M Li, K Mai, Q Ai, AC Shu-Chien	PloS one	2016
Altered lipid metabolism in the aging kidney identified by three layered omic analysis F Braun, MM Rinschen, V Bartels, P Frommolt, B Habermann, JH Hoeijmakers, B Schumacher, ME Dollé, RU Müller, T Benzing, B Schermer, CE Kurschat	Aging	2016
Mutant p53 Drives Cancer by Subverting Multiple Tumor Suppression Pathways S Haupt, D Raghu, Y Haupt	Frontiers in Oncology	2016
Advanced Running Performance by Genetic Predisposition in Male Dummerstorf Marathon Mice (DUhTP) Reveals Higher Sterol Regulatory Element-Binding Protein (SREBP) Related mRNA Expression in the Liver and Higher Serum Levels of Progesterone D Ohde, M Moeller, J Brenmoehl, C Walz, S Ponsuksili, M Schwerin, G Fuellen, A Hoeflich, P Aspichueta	PloS one	2016
Convergent Signaling Pathways Controlled by LRP1 (Receptor-related Protein 1) Cytoplasmic and Extracellular Domains Limit Cellular Cholesterol Accumulation ZE Asmar, J Terrand, M Jenty, L Host, M Mlih, A Zerr, H Justiniano, RL Matz, C Boudier, E Scholler, JM Garnier, D Bertaccini, D Thiersé, C Schaeffer, AV Dorsselaer, J Herz, V Bruban, P Boucher	The Journal of biological chemistry	2016
SREBP2 Activation Induces Hepatic Long-chain Acyl-CoA Synthetase 1 (ACSL1) Expression in Vivo and in Vitro through a Sterol Regulatory Element (SRE) Motif of the ACSL1 C-promoter AB Singh, CF Kan, B Dong, J Liu	The Journal of biological chemistry	2016
MeCP2 co-ordinates liver lipid metabolism with the NCoR1/HDAC3 corepressor complex SM Kyle, PK Saha, HM Brown, LC Chan, MJ Justice	Human Molecular Genetics	2016
The multifaceted roles of fatty acid synthesis in cancer F Röhrig, A Schulze	Nature Reviews Cancer	2016
Protective Effects of Ecklonia stolonifera Extract on Ethanol-Induced Fatty Liver in Rats CY Bang, JH Byun, HK Choi, JS Choi, SY Choung	Biomolecules & therapeutics	2016
Novel treatment options for lysosomal acid lipase deficiency: critical appraisal of sebelipase alfa K Su, E Donaldson, R Sharma	The Application of Clinical Genetics	2016
Physiological Suppression of Lipotoxic Liver Damage by Complementary Actions of HDAC3 and SCAP/SREBP R Papazyan, Z Sun, YH Kim, PM Titchenell, DA Hill, W Lu, M Damle, M Wan, Y Zhang, ER Briggs, JD Rabinowitz, MA Lazar	Cell Metabolism	2016
Selective targeting of mutant adenomatous polyposis coli (APC) in colorectal cancer L Zhang, PC Theodoropoulos, U Eskiocak, W Wang, YA Moon, B Posner, NS Williams, WE Wright, SB Kim, D Nijhawan, JK de Brabander, JW Shay	Science Translational Medicine	2016
Fermented rice bran supplementation mitigates metabolic syndrome in stroke-prone spontaneously hypertensive rats M Alauddin, H Shirakawa, T Koseki, N Kijima, Ardiansyah, S Budijanto, J Islam, T Goto, M Komai	BMC complementary and alternative medicine	2016
SREBP-2/PNPLA8 axis improves non-alcoholic fatty liver disease through activation of autophagy KY Kim, HJ Jang, YR Yang, KI Park, JK Seo, IW Shin, TI Jeon, S Ahn, PG Suh, TF Osborne, YK Seo	Scientific Reports	2016
TIFA as a crucial mediator for NLRP3 inflammasome TY Lin, TY Wei, S Li, SC Wang, M He, M Martin, J Zhang, TP Shentu, H Xiao, J Kang, KC Wang, Z Chen, S Chien, MD Tsai, JY Shyy	Proceedings of the National Academy of Sciences	2016
Ozone Inhalation Provokes Glucocorticoid-Dependent and -Independent Effects on Inflammatory and Metabolic Pathways EM Thomson, S Pal, J Guénette, MG Wade, E Atlas, AC Holloway, A Williams, R Vincent	Toxicological Sciences	2016
Hepatic Expression of Adenovirus 36 E4ORF1 Improves Glycemic Control and Promotes Glucose Metabolism Through AKT Activation TB McMurphy, W Huang, R Xiao, X Liu, NV Dhurandhar, L Cao	Diabetes	2016
Rab1 in cell signaling, cancer and other diseases XZ Yang, XX Li, YJ Zhang, L Rodriguez-Rodriguez, MQ Xiang, HY Wang, XF Zheng	Oncogene	2016
MicroRNA-124 promotes hepatic triglyceride accumulation through targeting tribbles homolog 3 X Liu, J Zhao, Q Liu, X Xiong, Z Zhang, Y Jiao, X Li, B Liu, Y Li, Y Lu	Scientific Reports	2016
Complex structure of the fission yeast SREBP-SCAP binding domains reveals an oligomeric organization X Gong, H Qian, W Shao, J Li, J Wu, JJ Liu, W Li, HW Wang, P Espenshade, N Yan	Cell Research	2016
Heat-Killed Lactobacillus salivarius and Lactobacillus johnsonii Reduce Liver Injury Induced by Alcohol In Vitro and In Vivo CH Chuang, CC Tsai, ES Lin, CS Huang, YY Lin, CC Lan, CC Huang	Molecules (Basel, Switzerland)	2016
Lipidomic Profiling of Lung Pleural Effusion Identifies Unique Metabotype for EGFR Mutants in Non-Small Cell Lung Cancer YS Ho, LY Yip, N Basri, VS Chong, CC Teo, E Tan, KL Lim, GS Tan, X Yang, SY Yeo, MS Koh, A Devanand, A Takano, EH Tan, DS Tan, TK Lim	Scientific Reports	2016
Lipid metabolism-related gene expression pattern of Atlantic bluefin tuna (Thunnus thynnus L.) larvae fed on live prey MB Betancor, A Ortega, F la Gándara, DR Tocher, G Mourente	Fish Physiology and Biochemistry	2016
Transcriptional Profiling Reveals a Common Metabolic Program in High-Risk Human Neuroblastoma and Mouse Neuroblastoma Sphere-Forming Cells M Liu, Y Xia, J Ding, B Ye, E Zhao, JH Choi, A Alptekin, C Yan, Z Dong, S Huang, L Yang, H Cui, Y Zha, HF Ding	Cell Reports	2016
SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism Y Oishi, NJ Spann, VM Link, ED Muse, T Strid, C Edillor, MJ Kolar, T Matsuzaka, S Hayakawa, J Tao, MU Kaikkonen, AF Carlin, MT Lam, I Manabe, H Shimano, A Saghatelian, CK Glass	Cell Metabolism	2016
Targeting Lipid Metabolic Reprogramming as Anticancer Therapeutics JY Cha, HJ Lee	Journal of Cancer Prevention	2016
Schisandra polysaccharide inhibits hepatic lipid accumulation by downregulating expression of SREBPs in NAFLD mice CM Wang, RS Yuan, WY Zhuang, JH Sun, JY Wu, H Li, JG Chen	Lipids in Health and Disease	2016
Herbal Formula HT048 Attenuates Diet-Induced Obesity by Improving Hepatic Lipid Metabolism and Insulin Resistance in Obese Rats Y Lee, B Jin, S Lee, MK Song, HH Bae, B Min, J Park, D Lee, H Kim	Molecules (Basel, Switzerland)	2016
The Role of miRNAs in Common Inflammatory Arthropathies: Osteoarthritis and Gouty Arthritis P Papanagnou, T Stivarou, M Tsironi	Biomolecules	2016
Endoplasmic Reticulum Stress Protein GRP78 Modulates Lipid Metabolism to Control Drug Sensitivity and Antitumor Immunity in Breast Cancer KL Cook, DR Soto-Pantoja, PA Clarke, MI Cruz, A Zwart, A Wa rri, L Hilakivi-Clarke, DD Roberts, R Clarke	Cancer research	2016
Perilipin-2 Deletion Impairs Hepatic Lipid Accumulation by Interfering with Sterol Regulatory Element-binding Protein (SREBP) Activation and Altering the Hepatic Lipidome AE Libby, E Bales, DJ Orlicky, JL McManaman	The Journal of biological chemistry	2016
Body Mass Index and Metastatic Renal Cell Carcinoma: Clinical and Biological Correlations L Albiges, AA Hakimi, W Xie, RR McKay, R Simantov, X Lin, JL Lee, BI Rini, S Srinivas, GA Bjarnason, S Ernst, LA Wood, UN Vaishamayan, SY Rha, N Agarwal, T Yuasa, SK Pal, A Bamias, EC Zabor, AJ Skanderup, H Furberg, AP Fay, G Velasco, MA Preston, KM Wilson, E Cho, DF McDermott, S Signoretti, DY Heng, TK Choueiri	Journal of Clinical Oncology	2016
Nonnuclear Estrogen Receptor Activation Improves Hepatic Steatosis in Female Mice KL Chambliss, J Barrera, M Umetani, J Umetani, SH Kim, Z Madak-Erdogan, L Huang, BS Katzenellenbogen, JA Katzenellenbogen, C Mineo, PW Shaul	Endocrinology	2016
Reduced miR-200b and miR-200c expression contributes to abnormal hepatic lipid accumulation by stimulating JUN expression and activating the transcription of srebp1 J Guo, W Fang, L Sun, Y Lu, L Dou, X Huang, M Sun, C Pang, J Qu, G Liu, J Li	Oncotarget	2016
Identifying gene–gene interactions that are highly associated with four quantitative lipid traits across multiple cohorts R De, SS Verma, E Holzinger, M Hall, A Burt, DS Carrell, DR Crosslin, GP Jarvik, H Kuivaniemi, IJ Kullo, LA Lange, MB Lanktree, EB Larson, KE North, AP Reiner, V Tragante, G Tromp, JG Wilson, FW Asselbergs, F Drenos, JH Moore, MD Ritchie, B Keating, D Gilbert-Diamond	Human Genetics	2016
Dose-dependent effects of siRNA-mediated inhibition of SCAP on PCSK9, LDLR, and plasma lipids in mouse and rhesus monkey KK Jensen, M Tadin-Strapps, S Wang, J Hubert, Y Kan, Y Ma, DG McLaren, SF Previs, KB Herath, A Mahsut, A Liaw, S Wang, SJ Stout, CA Keohan, G Forrest, D Coelho, S Yendluri, S Williams, M Koser, S Bartz, KO Akinsanya, S Pinto	Journal of lipid research	2016
Endoplasmic Reticulum Stress and Ca 2+ Depletion Differentially Modulate the Sterol Regulatory Protein PCSK9 to Control Lipid Metabolism P Lebeau, A Al-Hashimi, S Sood, Š Lhoták, P Yu, G Gyulay, G Paré, SR Chen, B Trigatti, A Prat, NG Seidah, RC Austin	The Journal of biological chemistry	2016
Autophagy in Diabetic Retinopathy Di Rosa M, Distefano G, Gagliano C, Rusciano D, Malaguarnera L	Current neuropharmacology	2016
European Obesity Summit (EOS) – Joint Congress of EASO and IFSO-EC, Gothenburg, Sweden, June 1 – 4, 2016: Abstracts	Obesity facts	2016
Genistein upregulates LDLR levels via JNK-mediated activation of SREBP-2 Kartawijaya M, Han HW, Kim Y, Lee SM	Food & Nutrition Research	2016
Sigumjang (fermented barley bran) water-soluble extracts inhibit the expression of adipogenic and lipogenic regulators in 3T3-L1 adipocytes Jeong H, Lee S, Kim SW, Kim D, Han GD	Food Science and Biotechnology	2016
Plasma cholesterol-lowering and transient liver dysfunction in mice lacking squalene synthase in the liver S Nagashima, H Yagyu, R Tozawa, F Tazoe, M Takahashi, T Kitamine, D Yamamuro, K Sakai, M Sekiya, H Okazaki, J Osuga, A Honda, S Ishibashi	Journal of lipid research	2015
Thyroid dysfunction associated with follicular cell steatosis in obese male mice and humans MH Lee, JU Lee, KH Joung, YK Kim, MJ Ryu, SE Lee, SJ Kim, HK Chung, MJ Choi, JY Chang, SH Lee, GR Kweon, HJ Kim, KS Kim, SM Kim, YS Jo, J Park, S Cheng, M Shong	Endocrinology	2015
Hyperinsulinemia Enhances Hepatic Expression of the Fatty Acid Transporter Cd36 and Provokes Hepatosteatosis and Hepatic Insulin Resistance P Steneberg, AG Sykaras, F Backlund, J Straseviciene, I Söderström, H Edlund	The Journal of biological chemistry	2015
Metabolic changes associated with tumor metastasis, part 2: Mitochondria, lipid and amino acid metabolism PE Porporato, VL Payen, B Baselet, P Sonveaux	Cellular and Molecular Life Sciences	2015
Metformin inhibits hepatocellular glucose, lipid and cholesterol biosynthetic pathways by transcriptionally suppressing steroid receptor coactivator 2 (SRC-2) A Madsen, O Bozickovic, JI Bjune, G Mellgren, JV Sagen	Scientific Reports	2015
Deepure Tea Improves High Fat Diet-Induced Insulin Resistance and Nonalcoholic Fatty Liver Disease JN Deng, J Li, HN Mu, YY Liu, MX Wang, CS Pan, JY Fan, F Ye, JY Han	Evidence-Based Complementary and Alternative Medicine	2015
Bile acids and sphingosine-1-phosphate receptor 2 in hepatic lipid metabolism E Kwong, Y Li, PB Hylemon, H Zhou	Acta Pharmaceutica Sinica B	2015
Flaxseed Oil Containing α -Linolenic Acid Ester of Plant Sterol Improved Atherosclerosis in ApoE Deficient Mice H Han, P Yan, L Chen, C Luo, H Gao, Q Deng, M Zheng, Y Shi, L Liu	Oxidative medicine and cellular longevity	2015
Oligonol suppresses lipid accumulation and improves insulin resistance in a palmitate-induced in HepG2 hepatocytes as a cellular steatosis model JY Park, Y Kim, JA Im, H Lee	BMC complementary and alternative medicine	2015
GRP78 rescues the ABCG5 ABCG8 sterol transporter in db/db mice Y Wang, K Su, NS Sabeva, A Ji, DR van der Westhuyzen, F Foufelle, X Gao, GA Graf	Metabolism	2015
Prosteatotic genes are associated with unsaturated fat suppression of saturated fat-induced hepatic steatosis in C57BL/6 mice T Geng, L Xia, S Russo, D Kamara, LA Cowart	Nutrition Research	2015
Cyclin Y Is Involved in the Regulation of Adipogenesis and Lipid Production W An, Z Zhang, L Zeng, Y Yang, X Zhu, J Wu, Y Chen	PloS one	2015
Clinically used selective oestrogen receptor modulators increase LDL receptor activity in primary human lymphocytes: SERMs increase LDL receptor activity F Cerrato, ME Fernández-Suárez, R Alonso, M Alonso, C Vázquez, O Pastor, P Mata, MA Lasunción, D Gómez-Coronado	British Journal of Pharmacology	2015
Thyroid hormone responsive protein spot 14 enhances lipogenesis in bovine mammary epithelial cells Y Cui, Z Liu, X Sun, X Hou, B Qu, F Zhao, X Gao, Z Sun, Q Li	In vitro cellular & developmental biology. Animal	2015
SREBP1 regulates tumorigenesis and prognosis of pancreatic cancer through targeting lipid metabolism Y Sun, W He, M Luo, Y Zhou, G Chang, W Ren, K Wu, X Li, J Shen, X Zhao, Y Hu	Tumor Biology	2015
Glial Lipid Droplets and ROS Induced by Mitochondrial Defects Promote Neurodegeneration L Liu, K Zhang, H Sandoval, S Yamamoto, M Jaiswal, E Sanz, Z Li, J Hui, BH Graham, A Quintana, HJ Bellen	Cell	2015
Sulforaphane, a cancer chemopreventive agent, induces pathways associated with membrane biosynthesis in response to tissue damage by aflatoxin B1 N Techapiesancharoenkij, JL Fiala, P Navasumrit, RG Croy, GN Wogan, JD Groopman, M Ruchirawat, JM Essigmann	Toxicology and Applied Pharmacology	2015
Advances in the targeted therapy of liposarcoma Guan, X Yu, H Wang, H Wang, J Zhang, G Li, J Cao, L Teng	OncoTargets and therapy	2015
Insulin-independent regulation of hepatic triglyceride synthesis by fatty acids DF Vatner, SK Majumdar, N Kumashiro, MC Petersen, Y Rahimi, AK Gattu, M Bears, JP Camporez, GW Cline, MJ Jurczak, VT Samuel, GI Shulman	Proceedings of the National Academy of Sciences	2015
Effect of sofosbuvir and ribavirin treatment on peripheral and hepatic lipid metabolism in chronic hepatitis C virus, genotype 1-infected patients: HEPATOLOGY, Vol. XX, No. X, 2014 EG Meissner, YJ Lee, A Osinusi, Z Sims, J Qin, D Sturdevant, J McHutchison, M Subramanian, M Sampson, S Naggie, K Patel, AT Remaley, H Masur, S Kottilil	Hepatology	2015
Can Tetracycline Antibiotics Duplicate the Ability of Azithromycin to Stimulate Human Meibomian Gland Epithelial Cell Differentiation?: Y Liu, WR Kam, J Ding, DA Sullivan	Cornea	2015
Hedgehog Signaling and Steroidogenesis I Finco, CR LaPensee, KT Krill, GD Hammer	Annual Review of Physiology	2015
Alloxan-Induced Diabetes Causes Morphological and Ultrastructural Changes in Rat Liver that Resemble the Natural History of Chronic Fatty Liver Disease in Humans AN Lucchesi, LL Cassettari, CT Spadella	Journal of Diabetes Research	2015
The small molecule fenpropimorph rapidly converts chloroplast membrane lipids to triacylglycerols in Chlamydomonas reinhardtii H Kim, S Jang, S Kim, Y Yamaoka, D Hong, WY Song, I Nishida, Y Li-Beisson, Y Lee	Frontiers in microbiology	2015
A Novel Sterol Regulatory Element-Binding Protein Gene (sreA) Identified in Penicillium digitatum Is Required for Prochloraz Resistance, Full Virulence and erg11 (cyp51) Regulation J Liu, Y Yuan, Z Wu, N Li, Y Chen, T Qin, H Geng, L Xiong, D Liu, RA Cramer	PloS one	2015
Structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition X Gong, J Li, W Shao, J Wu, H Qian, R Ren, P Espenshade, N Yan	Cell Research	2015
The Interplay of the Gut Microbiome, Bile Acids, and Volatile Organic Compounds NM Sagar, IA Cree, JA Covington, RP Arasaradnam	Gastroenterology Research and Practice	2015
2-(3-Benzoylthioureido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid ameliorates metabolic disorders in high-fat diet-fed mice J Zhang, L Zhang, D Chen, Y Fu, F Zhang, L Yang, C Xia, H Jiang, C Tang, Z Xie, F Yang, J Li, J Tang, J Li	Acta Pharmacologica Sinica	2015
Comparison of Electrospray Ionization and Atmospheric Chemical Ionization Coupled with the Liquid Chromatography-Tandem Mass Spectrometry for the Analysis of Cholesteryl Esters HR Lee, S Kochhar, SM Shim	International Journal of Analytical Chemistry	2015
Accumulation of Advanced Glycation End-Products and Activation of the SCAP/SREBP Lipogenetic Pathway Occur in Diet-Induced Obese Mouse Skeletal Muscle R Mastrocola, M Collino, D Nigro, F Chiazza, G D’Antona, M Aragno, MA Minetto, H Guillou	PloS one	2015
Effects of Dietary Pantothenic Acid on Growth, Intestinal Function, Anti-Oxidative Status and Fatty Acids Synthesis of Juvenile Blunt Snout Bream Megalobrama amblycephala Y Qian, XF Li, DD Zhang, DS Cai, HY Tian, WB Liu, F Missirlis	PloS one	2015
The loss of Tm7sf gene accelerates skin papilloma formation in mice I Bellezza, L Gatticchi, R Sordo, MJ Peirce, A Sidoni, R Roberti, A Minelli	Scientific Reports	2015
A Century of Cholesterol and Coronaries: From Plaques to Genes to Statins JL Goldstein, MS Brown	Cell	2015
Diosgenin, 4-Hydroxyisoleucine, and Fiber from Fenugreek: Mechanisms of Actions and Potential Effects on Metabolic Syndrome S Fuller, JM Stephens	Advances in nutrition (Bethesda, Md.)	2015
The Nuclear Receptor FXR Uncouples the Actions of miR-33 From SREBP-2 EJ Tarling, H Ahn, TQ de Vallim	Arteriosclerosis, thrombosis, and vascular biology	2015
Fatty Acid Signaling: The New Function of Intracellular Lipases Z Papackova, M Cahova	International journal of molecular sciences	2015
Long-Term Hyperphagia and Caloric Restriction Caused by Low- or High-Density Husbandry Have Differential Effects on Zebrafish Postembryonic Development, Somatic Growth, Fat Accumulation and Reproduction S Leibold, M Hammerschmidt, JF Rawls	PloS one	2015
Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis J Miao, AV Ling, PV Manthena, ME Gearing, MJ Graham, RM Crooke, KJ Croce, RM Esquejo, CB Clish, E Torrecilla, GF Vázquez, MA Rubio, L Cabrerizo, A Barabash, AS Pernaute, AJ Torres, D Vicent, SB Biddinger	Nature Communications	2015
Higher Protein Kinase C ζ in Fatty Rat Liver and Its Effect on Insulin Actions in Primary Hepatocytes W Chen, MR Goff, H Kuang, G Chen, J Peterson	PloS one	2015
Fatty acid synthase-positive hepatocytes and subsequent steatosis in rat livers by irinotecan T Sawano, T Shimizu, T Yamada, N Nanashima, T Miura, S Morohashi, D Kudo, F Hui, H Kijima, K Hakamada, S Tsuchida	Oncology reports	2015
Inhibition of mTOR complex 2 induces GSK3/FBXW7-dependent degradation of sterol regulatory element-binding protein 1 (SREBP1) and suppresses lipogenesis in cancer cells S Li, YT Oh, P Yue, FR Khuri, SY Sun	Oncogene	2015
Activated α 2 -Macroglobulin Binding to Human Prostate Cancer Cells Triggers Insulin-like Responses UK Misra, SV Pizzo	The Journal of biological chemistry	2015
Sagunja-Tang Improves Lipid Related Disease in a Postmenopausal Rat Model and HepG2 Cells H Go, JA Ryuk, HW Lee, IS Park, KJ Kil, S Park, D Kim, BS Ko	Evidence-Based Complementary and Alternative Medicine	2015
REPTOR and REPTOR-BP Regulate Organismal Metabolism and Transcription Downstream of TORC1 M Tiebe, M Lutz, A De La Garza, T Buechling, M Boutros, AA Teleman	Developmental Cell	2015
Transcriptome profiling identifies p53 as a key player during calreticulin deficiency: Implications in lipid accumulation S Vig, P Talwar, K Kaur, R Srivastava, AK Srivastava, M Datta	Cell cycle (Georgetown, Tex.)	2015
Sfrp2 is a transcriptional target of SREBP-1 in mouse chondrogenic cells MJ Kim, JE Kim, W Lee, SY Park	Molecular and Cellular Biochemistry	2015
Insulin Resistance Induces Posttranslational Hepatic Sortilin 1 Degradation in Mice J Li, DJ Matye, T Li	The Journal of biological chemistry	2015
Effect of Ganoderma lucidum spores intervention on glucose and lipid metabolism gene expression profiles in type 2 diabetic rats F Wang, Z Zhou, X Ren, Y Wang, R Yang, J Luo, P Strappe	Lipids in Health and Disease	2015
Fructose Metabolism and Relation to Atherosclerosis, Type 2 Diabetes, and Obesity A Kolderup, B Svihus	Journal of nutrition and metabolism	2015
Primary cilium suppression by SREBP1c involves distortion of vesicular trafficking by PLA2G3 HL Gijs, N Willemarck, F Vanderhoydonc, NA Khan, J Dehairs, R Derua, E Waelkens, Y Taketomi, M Murakami, P Agostinis, W Annaert, JV Swinnen	Molecular biology of the cell	2015
Herbal SGR Formula Prevents Acute Ethanol-Induced Liver Steatosis via Inhibition of Lipogenesis and Enhancement Fatty Acid Oxidation in Mice P Qiu, X Li, D Kong, H Li, C Niu, S Pan	Evidence-Based Complementary and Alternative Medicine	2015
Oncogenic PI3K and K-Ras stimulate de novo lipid synthesis through mTORC1 and SREBP SJ Ricoult, JL Yecies, I Ben-Sahra, BD Manning	Oncogene	2015
mTORC1 signaling activates NRF1 to increase cellular proteasome levels Y Zhang, BD Manning	Cell cycle (Georgetown, Tex.)	2015
MARCKS-dependent mucin clearance and lipid metabolism in ependymal cells are required for maintenance of forebrain homeostasis during aging N Muthusamy, LJ Sommerville, AJ Moeser, DJ Stumpo, P Sannes, K Adler, PJ Blackshear, JM Weimer, HT Ghashghaei	Aging Cell	2015
Liver steatosis in hepatitis C patients E González-Reimers	World journal of hepatology	2015
p54nrb/NONO regulates lipid metabolism and breast cancer growth through SREBP-1A Z Zhu, X Zhao, L Zhao, H Yang, L Liu, J Li, J Wu, F Yang, G Huang, J Liu	Oncogene	2015
Tuberous Sclerosis Complex 2 Loss Increases Lysophosphatidylcholine Synthesis in Lymphangioleiomyomatosis C Priolo, SJ Ricoult, D Khabibullin, H Filippakis, J Yu, BD Manning, C Clish, EP Henske	American journal of respiratory cell and molecular biology	2015
Palmiwon attenuates hepatic lipid accumulation and hyperlipidemia in a menopausal rat model: H Go, JA Ryuk, HW Lee, BS Ko	Menopause (New York, N.Y.)	2015
Dietary ε-Polylysine Decreased Serum and Liver Lipid Contents by Enhancing Fecal Lipid Excretion Irrespective of Increased Hepatic Fatty Acid Biosynthesis-Related Enzymes Activities in Rats R Hosomi, D Yamamoto, R Otsuka, T Nishiyama, M Yoshida, K Fukunaga	Preventive Nutrition and Food Science	2015
Wedelolactone Regulates Lipid Metabolism and Improves Hepatic Steatosis Partly by AMPK Activation and Up-Regulation of Expression of PPARα/LPL and LDLR Y Zhao, L Peng, L Yang, X Xu, W Li, X Luo, X Jin, Y Zhang	PloS one	2015
Resveratrol and SRT1720 Elicit Differential Effects in Metabolic Organs and Modulate Systemic Parameters Independently of Skeletal Muscle Peroxisome Proliferator-activated Receptor γ Co-activator 1α (PGC-1α) K Svensson, S Schnyder, V Albert, B Cardel, L Quagliata, LM Terracciano, C Handschin	The Journal of biological chemistry	2015
The CREB coactivator CRTC2 controls hepatic lipid metabolism by regulating SREBP1 J Han, E Li, L Chen, Y Zhang, F Wei, J Liu, H Deng, Y Wang	Nature	2015
Scap is required for sterol synthesis and crypt growth in intestinal mucosa MR McFarlane, MJ Cantoria, AG Linden, BA January, G Liang, LJ Engelking	Journal of lipid research	2015
Construction and evaluation of an adenoviral vector for the liver-specific expression of the serine/arginine-rich splicing factor, SRSF3 AL Suchanek, LM Salati	Plasmid	2015
Hepatic CEACAM1 Over-Expression Protects Against Diet-Induced Fibrosis and Inflammation in White Adipose Tissue SG Lester, L Russo, SS Ghanem, SS Khuder, AM DeAngelis, EL Esakov, TA Bowman, G Heinrich, QY Al-Share, MF McInerney, WM Philbrick, SM Najjar	Frontiers in Endocrinology	2015
Metabolic regulation of T cell differentiation and function BV Park, F Pan	Molecular Immunology	2015
Molecular mechanisms of fatty liver in obesity L Gan, W Xiang, B Xie, L Yu	Frontiers of Medicine	2015
Xanthohumol Improves Diet-induced Obesity and Fatty Liver by Suppressing Sterol Regulatory Element-binding Protein (SREBP) Activation S Miyata, J Inoue, M Shimizu, R Sato	The Journal of biological chemistry	2015
Simultaneous deletion of the methylcytosine oxidases Tet1 and Tet3 increases transcriptome variability in early embryogenesis J Kang, M Lienhard, WA Pastor, A Chawla, M Novotny, A Tsagaratou, RS Lasken, EC Thompson, MA Surani, SB Koralov, S Kalantry, L Chavez, A Rao	Proceedings of the National Academy of Sciences	2015
PAQR3 modulates cholesterol homeostasis by anchoring Scap/SREBP complex to the Golgi apparatus D Xu, Z Wang, Y Zhang, W Jiang, Y Pan, BL Song, Y Chen	Nature Communications	2015
Effect of anti-hyperlipidemia drugs on the alpha-tocopherol concentration and their potential for murine malaria infection A Kume, MS Herbas, M Shichiri, N Ishida, H Suzuki	Parasitology Research	2015
ApoA-I-Directed Therapies for the Management of Atherosclerosis JS Millar, M Cuchel	Current Atherosclerosis Reports	2015
The Flavone Luteolin Suppresses SREBP-2 Expression and Post-Translational Activation in Hepatic Cells TY Wong, S Lin, LK Leung, FM Sladek	PloS one	2015
miR-122 Regulates LH Receptor Expression by Activating Sterol Response Element Binding Protein in Rat Ovaries B Menon, T Gulappa, KM Menon	Endocrinology	2015
Pregnane X Receptor-Humanized Mice Recapitulate Gender Differences in Ethanol Metabolism but Not Hepatotoxicity K Spruiell, AA Gyamfi, ST Yeyeodu, RM Richardson, FJ Gonzalez, MA Gyamfi	The Journal of pharmacology and experimental therapeutics	2015
Impact of SCP-2/SCP-x gene ablation and dietary cholesterol on hepatic lipid accumulation D Klipsic, D Landrock, GG Martin, AL McIntosh, KK Landrock, JT Mackie, F Schroeder, AB Kier	AJP Gastrointestinal and Liver Physiology	2015
Golgi Associated HIF1a Serves as a Reserve in Melanoma Cells: G OLGI A SSOCIATED HIF1a IN M ELANOMA AJ Lakhter, T Lahm, HE Broxmeyer, SR Naidu	Journal of Cellular Biochemistry	2015
The Regulation of Reverse Cholesterol Transport and Cellular Cholesterol Homeostasis by MicroRNAs D DiMarco, M Fernandez	Biology : open access journal	2015
Effect of Creosote Bush-Derived NDGA on Expression of Genes Involved in Lipid Metabolism in Liver of High-Fructose Fed Rats: Relevance to NDGA Amelioration of Hypertriglyceridemia and Hepatic Steatosis H Zhang, Y Li, J Hu, WJ Shen, M Singh, X Hou, A Bittner, S Bittner, Y Cortez, J Tabassum, FB Kraemer, S Azhar, MB Aguila	PloS one	2015
The miRNA Interactome in Metabolic Homeostasis SM Hartig, MP Hamilton, DA Bader, SE McGuire	Trends in Endocrinology & Metabolism	2015
An Ester of β-Hydroxybutyrate Regulates Cholesterol Biosynthesis in Rats and a Cholesterol Biomarker in Humans MF Kemper, S Srivastava, MT King, K Clarke, RL Veech, RJ Pawlosky	Lipids	2015
Hypercholesterolemia with consumption of PFOA-laced Western diets is dependent on strain and sex of mice SL Rebholz, T Jones, RL Herrick, C Xie, AM Calafat, SM Pinney, LA Woollett	Toxicology Reports	2015
Insulin Dissociates the Effects of Liver X Receptor on Lipogenesis, Endoplasmic Reticulum Stress, and Inflammation X Sun, ME Haas, J Miao, A Mehta, MJ Graham, RM Crooke, JP de Barros, JG Wang, M Aikawa, D Masson, SB Biddinger	The Journal of biological chemistry	2015
Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling AG York, KJ Williams, JP Argus, QD Zhou, G Brar, L Vergnes, EE Gray, A Zhen, NC Wu, DH Yamada, CR Cunningham, EJ Tarling, MQ Wilks, D Casero, DH Gray, AK Yu, ES Wang, DG Brooks, R Sun, SG Kitchen, TT Wu, K Reue, DB Stetson, SJ Bensinger	Cell	2015
Selective targeting of nuclear receptor FXR by avermectin analogues with therapeutic effects on nonalcoholic fatty liver disease L Jin, R Wang, Y Zhu, W Zheng, Y Han, F Guo, FB Ye, Y Li	Scientific Reports	2015
Effect of high-intensity exercise and high-fat diet on lipid metabolism in the liver of rats MH Suk, YA Shin	Journal of Exercise Nutrition & Biochemistry	2015
The anti-obesity effects of a tuna peptide on 3T3-L1ï¿½adipocytes are mediated by the inhibition of the expression of lipogenic and adipogenic genes and by the activation of the Wnt/β-catenin signaling pathway YM Kim, IH Kim, JW Choi, MK Lee, TJ Nam	International journal of molecular medicine	2015
Reprogramming of glucose, fatty acid and amino acid metabolism for cancer progression Z Li, H Zhang	Cellular and Molecular Life Sciences	2015
Glucose-Mediated N-glycosylation of SCAP Is Essential for SREBP-1 Activation and Tumor Growth C Cheng, P Ru, F Geng, J Liu, JY Yoo, X Wu, X Cheng, V Euthine, P Hu, JY Guo, E Lefai, B Kaur, A Nohturfft, J Ma, A Chakravarti, D Guo	Cancer Cell	2015
Dietary fiber prevents obesity-related liver lipotoxicity by modulating sterol-regulatory element binding protein pathway in C57BL/6J mice fed a high-fat/cholesterol diet S Han, J Jiao, W Zhang, J Xu, Z Wan, W Zhang, X Gao, L Qin	Scientific Reports	2015
Revisiting Human Cholesterol Synthesis and Absorption: The Reciprocity Paradigm and its Key Regulators PA Alphonse, PJ Jones	Lipids	2015
A Herbal Formula HT048, Citrus unshiu and Crataegus pinnatifida, Prevents Obesity by Inhibiting Adipogenesis and Lipogenesis in 3T3-L1 Preadipocytes and HFD-Induced Obese Rats Y Lee, YS Kim, M Song, M Lee, J Park, H Kim	Molecules (Basel, Switzerland)	2015
SREBP-2-deficient and hypomorphic mice reveal roles for SREBP-2 in embryonic development and SREBP-1c expression L Vergnes, RG Chin, TA Vallim, LG Fong, TF Osborne, SG Young, K Reue	Journal of lipid research	2015
Transcriptional and Translational Modulation of myo -Inositol Oxygenase (Miox) by Fatty Acids: IMPLICATIONS IN RENAL TUBULAR INJURY INDUCED IN OBESITY AND DIABETES T Tominaga, RK Dutta, D Joladarashi, T Doi, JK Reddy, YS Kanwar	The Journal of biological chemistry	2015
Combination of deep sea water and Sesamum indicumï¿½leaf extract prevents high-fat diet-induced obesity through AMPK activation in visceral adipose tissue H Yuan, S Chung, Q Ma, L Ye, G Piao	Experimental and therapeutic medicine	2015
Deubiquitylase Inhibition Reveals Liver X Receptor-independent Transcriptional Regulation of the E3 Ubiquitin Ligase IDOL and Lipoprotein Uptake JK Nelson, EC Cook, A Loregger, MA Hoeksema, S Scheij, I Kovacevic, PL Hordijk, H Ovaa, N Zelcer	The Journal of biological chemistry	2015
The Hepatitis C Virus-induced NLRP3 Inflammasome Activates the Sterol Regulatory Element-binding Protein (SREBP) and Regulates Lipid Metabolism S McRae, J Iqbal, M Sarkar-Dutta, S Lane, A Nagaraj, N Ali, G Waris	The Journal of biological chemistry	2015
Treatment with PPAR α Agonist Clofibrate Inhibits the Transcription and Activation of SREBPs and Reduces Triglyceride and Cholesterol Levels in Liver of Broiler Chickens L Zhang, C Li, F Wang, S Zhou, M Shangguan, L Xue, B Zhang, F Ding, D Hui, A Liang, D He	PPAR Research	2015
Suppressor of Cytokine Signaling-3 (SOCS-3) Induces Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) Expression in Hepatic HepG2 Cell Line M Ruscica, C Ricci, C Macchi, P Magni, R Cristofani, J Liu, A Corsini, N Ferri	The Journal of biological chemistry	2015
Identification of NPC1 as the target of U18666A, an inhibitor of lysosomal cholesterol export and Ebola infection: The predicted topology of the polytopic protein is based on the data of Davies and Ioannou (2000). Each of the five known functional domains of the protein are shown in a different color. The locations of three loss-of-function mutations referred to in the manuscript are indicated. aa, amino acid; NTD, N-terminal domain F Lu, Q Liang, L Abi-Mosleh, A Das, JK de Brabander, JL Goldstein, MS Brown	eLife	2015
Shifting eating to the circadian rest phase misaligns the peripheral clocks with the master SCN clock and leads to a metabolic syndrome A Mukherji, A Kobiita, M Damara, N Misra, H Meziane, MF Champy, P Chambon	Proceedings of the National Academy of Sciences	2015
Glycogen synthase kinase-3-mediated phosphorylation of serine 73 targets sterol response element binding protein-1c (SREBP-1c) for proteasomal degradation Q Dong, F Giorgianni, S Beranova-Giorgianni, X Deng, RN O'Meally, D Bridges, EA Park, RN Cole, MB Elam, R Raghow	Bioscience Reports	2015
Neuregulin-activated ERBB4 induces the SREBP-2 cholesterol biosynthetic pathway and increases low-density lipoprotein uptake JW Haskins, S Zhang, RE Means, JK Kelleher, GW Cline, A Canfran-Duque, Y Suarez, DF Stern	Science signaling	2015
A MARCH6 and IDOL E3 ubiquitin ligase circuit uncouples cholesterol synthesis from lipoprotein uptake in hepatocytes A Loregger, EC Cook, JK Nelson, M Moeton, LJ Sharpe, S Engberg, M Karimova, G Lambert, AJ Brown, N Zelcer	Molecular and cellular biology	2015
Plasma proprotein convertase subtilisin/kexin type 9 levels and the risk of first cardiovascular events PM Ridker, N Rifai, G Bradwin, L Rose	European Heart Journal	2015
MicroRNA-26a/b and their host genes synergistically regulate triacylglycerol synthesis by targeting the INSIG1 gene H Wang, J Luo, T Zhang, H Tian, Y Ma, H Xu, D Yao, JJ Loor	RNA biology	2015
The expression of genes involved in jejunal lipogenesis and lipoprotein synthesis is altered in morbidly obese subjects with insulin resistance C Gutierrez-Repiso, F Rodriguez-Pacheco, J Garcia-Arnes, S Valdes, M Gonzalo, F Soriguer, FJ Moreno-Ruiz, A Rodriguez-Cañete, JL Gallego-Perales, G Alcain-Martinez, L Vazquez-Pedreño, S Lopez-Enriquez, S Garcia-Serrano, L Garrido-Sanchez, E Garcia-Fuentes	Laboratory Investigation	2015
MicroRNA-21 is a potential link between non-alcoholic fatty liver disease and hepatocellular carcinoma via modulation of the HBP1-p53-Srebp1c pathway H Wu, R Ng, X Chen, CJ Steer, G Song	Gut	2015
Severity of non-alcoholic fatty liver disease is associated with high systemic levels of tumor necrosis factor alpha and low serum interleukin 10 in morbidly obese patients G Paredes-Turrubiarte, A González-Chávez, R Pérez-Tamayo, BY Salazar-Vázquez, VS Hernández, N Garibay-Nieto, JM Fragoso, G Escobedo	Zeitschrift fü Die Gesamte Experimentelle Medizin	2015
Lipids rule: resetting lipid metabolism restores T cell function in systemic lupus erythematosus Yoko Kidani, Steven Bensinger	Journal of Clinical Investigation	2014
Oxidative Stress Activates Endothelial Innate Immunity via Sterol Regulatory Element Binding Protein 2 (SREBP2) Transactivation of MiRNA-92a Z Chen, L Wen, M Martin, CY Hsu, L Fang, FM Lin, TY Lin, MJ Geary, G Geary, Y Zhao, DA Johnson, JW Chen, SJ Lin, S Chien, HD Huang, YI Miller, PH Huang, JY Shyy	Circulation	2014
PAS Kinase Drives Lipogenesis through SREBP-1 Maturation X Wu, D Romero, WI Swiatek, I Dorweiler, CK Kikani, H Sabic, BS Zweifel, J McKearn, JT Blitzer, GA Nickols, J Rutter	Cell Reports	2014
Intestinal nuclear receptors in HDL cholesterol metabolism C Degirolamo, C Sabbà, A Moschetta	Journal of lipid research	2014
Arginase inhibition ameliorates hepatic metabolic abnormalities in obese mice J Moon, HJ Do, Y Cho, MJ Shin	PloS one	2014
PCSK9 and LDLR degradation: regulatory mechanisms in circulation and in cells TA Lagace	Current Opinion in Lipidology	2014
Genetic, anatomic, and clinical determinants of human serum sterol and vitamin D levels AR Stiles, J Kozlitina, BM Thompson, JG McDonald, KS King, DW Russell	Proceedings of the National Academy of Sciences	2014
Energy metabolism in the liver L Rui	Comprehensive Physiology	2014
Genetic Alterations Affecting Cholesterol Metabolism and Human Fertility AM DeAngelis, M Roy-O'Reilly, A Rodriguez	Biology of reproduction	2014
PKA/AMPK signaling in relation to adiponectin’s antiproliferative effect on multiple myeloma cells EA Medina, K Oberheu, SR Polusani, V Ortega, GV Velagaleti, BO Oyajobi	Leukemia	2014
Nonalcoholic Fatty Liver Disease: Pathogenesis and Therapeutics from a Mitochondria-Centric Perspective AM Gusdon, K Song, S Qu	Oxidative medicine and cellular longevity	2014
mTOR signaling in tumorigenesis K Xu, P Liu, W Wei	Biochimica et Biophysica Acta (BBA) - Reviews on Cancer	2014
Pathogenesis and therapeutic approaches for non-alcoholic fatty liver disease H Yoon	World journal of hepatology	2014
Saponin as regulator of biofuel: implication for ethnobotanical management of diabetes OO Elekofehinti, IO Omotuyi, JP Kamdem, OC Ejelonu, GV Alves, IG Adanlawo, JB Rocha	Journal of Physiology and Biochemistry	2014
Recent insights into farnesoid X receptor in non-alcoholic fatty liver disease JY Xu	World journal of gastroenterology : WJG	2014
Bile Acid Signaling in Metabolic Disease and Drug Therapy T Li, JY Chiang	Pharmacological reviews	2014
RNF20 regulates hepatic lipid metabolism through PKA-dependent SREBP1c degradation JH Lee, GY Lee, H Jang, SS Choe, SH Koo, JB Kim	Hepatology	2014
Elevated hepatic 11 -hydroxysteroid dehydrogenase type 1 induces insulin resistance in uremia A Chapagain, PW Caton, J Kieswich, P Andrikopoulos, N Nayuni, JH Long, SM Harwood, SP Webster, MJ Raftery, C Thiemermann, BR Walker, JR Seckl, R Corder, MM Yaqoob	Proceedings of the National Academy of Sciences	2014
Novel modulators of hepatosteatosis, inflammation and fibrogenesis MR Lakshman, K Reyes-Gordillo, R Varatharajalu, J Arellanes-Robledo, LC Leckey, M Garige, R Shah	Hepatology International	2014
Adverse Signaling of Scavenger Receptor Class B1 and PGC1s in Alcoholic Hepatosteatosis and Steatohepatitis, and Protection by Betaine in Rat R Varatharajalu, M Garige, LC Leckey, J Arellanes-Robledo, K Reyes-Gordillo, R Shah, MR Lakshman	The American Journal of Pathology	2014
Pharmacogenomics of sterol synthesis and statin use in schizophrenia subjects treated with antipsychotics TJ Vassas, KJ Burghardt, VL Ellingrod	Pharmacogenomics	2014
Protective effects of farnesoid X receptor (FXR) on hepatic lipid accumulation are mediated by hepatic FXR and independent of intestinal FGF15 signal J Schmitt, B Kong, B Stieger, O Tschopp, SM Schultze, M Rau, A Weber, B Müllhaupt, GL Guo, A Geier	Liver International	2014
Trypanosoma cruzi infection results in an increase in intracellular cholesterol C Johndrow, R Nelson, H Tanowitz, LM Weiss, F Nagajyothi	Microbes and Infection	2014
Hydrogen peroxide sensing, signaling and regulation of transcription factors HS Marinho, C Real, L Cyrne, H Soares, F Antunes	Redox Biology	2014
mTOR signaling and transcriptional regulation in T lymphocytes H Zeng, H Chi	Transcription	2014
Mechanisms of Liver Injury in Non-Alcoholic Steatohepatitis CC Duwaerts, JJ Maher	Current Hepatology Reports	2014
Comprehensive analyses of DNA repair pathways, smoking and bladder cancer risk in Los Angeles and Shanghai: DNA repair, smoking and bladder cancer risk R Corral, JP Lewinger, DV Berg, AD Joshi, JM Yuan, M Gago-Dominguez, VK Cortessis, MC Pike, DV Conti, DC Thomas, CK Edlund, YT Gao, YB Xiang, W Zhang, YC Su, MC Stern	International Journal of Cancer	2014
Brain microRNAs and insights into biological functions and therapeutic potential of brain enriched miRNA-128 YK Adlakha, N Saini	Molecular Cancer	2014
ER stress and hepatic lipid metabolism H Zhou, R Liu	Frontiers in Genetics	2014
Cholesterol as a causative factor in Alzheimer's disease: a debatable hypothesis WG Wood, L Li, WE Müller, GP Eckert	Journal of Neurochemistry	2014
The Effect and Mechanism of Tamoxifen-Induced Hepatocyte Steatosis in Vitro F Zhao, P Xie, J Jiang, L Zhang, W An, Y Zhan	International journal of molecular sciences	2014
SIRT1 and other sirtuins in metabolism HC Chang, L Guarente	Trends in Endocrinology & Metabolism	2014
The Roles of Vitamin A in the Regulation of Carbohydrate, Lipid, and Protein Metabolism W Chen, G Chen	Journal of Clinical Medicine	2014
Enhanced circulating PCSK9 concentration by berberine through SREBP-2 pathway in high fat diet-fed rats YJ Jia, RX Xu, J Sun, Y Tang, JJ Li	Journal of Translational Medicine	2014
Immunologic, metabolic and genetic factors in hepatitis C virus infection NA Fierro, K Gonzalez-Aldaco, R Torres-Valadez, E Martinez-Lopez, S Roman, A Panduro	World journal of gastroenterology : WJG	2014
Age-associated alterations in cholesterol homeostasis: evidence from a cross-sectional study in a Northern Italy population M Bertolotti, C Mussi, E Pellegrini, A Magni, MD Puppo, S Ognibene, L Carulli, C Anzivino, E Baldelli, P Loria, N Carulli	Clinical Interventions in Aging	2014
Zinc finger transcription factors displaced SREBP proteins as the major Sterol regulators during Saccharomycotina evolution SL Maguire, C Wang, LM Holland, F Brunel, C Neuvéglise, JM Nicaud, M Zavrel, TC White, KH Wolfe, G Butler	PLoS genetics	2014
Genetic and Chemical Correction of Cholesterol Accumulation and Impaired Autophagy in Hepatic and Neural Cells Derived from Niemann-Pick Type C Patient-Specific iPS Cells D Maetzel, S Sarkar, H Wang, L Abi-Mosleh, P Xu, AW Cheng, Q Gao, M Mitalipova, R Jaenisch	Stem Cell Reports	2014
Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy RM Ivatt, A Sanchez-Martinez, VK Godena, S Brown, E Ziviani, AJ Whitworth	Proceedings of the National Academy of Sciences	2014
Regulation of the cholesterol biosynthetic pathway and its integration with fatty acid biosynthesis in the oleaginous microalga Nannochloropsis oceanica Y Lu, W Zhou, L Wei, J Li, J Jia, F Li, SM Smith, J Xu	Biotechnology for Biofuels	2014
Hepatic Oxidative Stress Promotes Insulin-STAT-5 Signaling and Obesity by Inactivating Protein Tyrosine Phosphatase N2 EN Gurzov, M Tran, MA Fernandez-Rojo, TL Merry, X Zhang, Y Xu, A Fukushima, MJ Waters, MJ Watt, S Andrikopoulos, BG Neel, T Tiganis	Cell Metabolism	2014
MicroRNA-33b knock-in mice for an intron of sterol regulatory element-binding factor 1 (Srebf1) exhibit reduced HDL-C in vivo T Horie, T Nishino, O Baba, Y Kuwabara, T Nakao, M Nishiga, S Usami, M Izuhara, F Nakazeki, Y Ide, S Koyama, N Sowa, N Yahagi, H Shimano, T Nakamura, K Hasegawa, N Kume, M Yokode, T Kita, T Kimura, K Ono	Scientific Reports	2014
microRNAs and HDL life cycle A Canfran-Duque, CM Ramirez, L Goedeke, CS Lin, C Fernandez-Hernando	Cardiovascular Research	2014
microRNA regulation of lipoprotein metabolism L Goedeke, JF Aranda, C Fernández-Hernando	Current Opinion in Lipidology	2014
Unravelling the mysterious roles of melanocortin-3 receptors in metabolic homeostasis and obesity using mouse genetics C Girardet, K Begriche, A Ptitsyn, RA Koza, AA Butler	International Journal of Obesity Supplements	2014
Ezetimibe suppresses cholesterol accumulation in lipid-loaded vascular smooth muscle cells in vitro via MAPK signaling L Qin, Y Yang, Y Yang, N Zhu, Y Gong, C Zhang, S Li, D Liao	Acta Pharmacologica Sinica	2014
Effects of dietary sea cucumber saponin on the gene expression rhythm involved in circadian clock and lipid metabolism in mice during nighttime-feeding M Wen, J Cui, J Xu, Y Xue, J Wang, C Xue, Y Wang	Journal of Physiology and Biochemistry	2014
Recent Advances in Understanding of NASH: MicroRNAs as Both Biochemical Markers and Players R Vincent, A Sanyal	Current Pathobiology Reports	2014
HIV protease inhibitors in gut barrier dysfunction and liver injury X Wu, Y Li, K Peng, H Zhou	Current Opinion in Pharmacology	2014
Molecular pathways in non-alcoholic fatty liver disease A Berlanga, E Guiu-Jurado, JA Porras, T Auguet	Clinical and experimental gastroenterology	2014
Three pools of plasma membrane cholesterol and their relation to cholesterol homeostasis A Das, MS Brown, DD Anderson, JL Goldstein, A Radhakrishnan	eLife	2014
Chronic Exposure to Low-Dose Arsenic Modulates Lipogenic Gene Expression in Mice: ARSENIC EFFECT ON LIPID-REGULATING GENES AO Adebayo, F Zandbergen, CD Kozul-Horvath, PA Gruppuso, JW Hamilton	Journal of Biochemical and Molecular Toxicology	2014
HIV-1 Nef Is Transferred from Expressing T Cells to Hepatocytic Cells through Conduits and Enhances HCV Replication IW Park, Y Fan, X Luo, MG Ryou, J Liu, L Green, JJ He, F Ceccherini-Silberstein	PloS one	2014
Steatosis and Steatohepatitis: Complex Disorders K Bettermann, T Hohensee, J Haybaeck	International journal of molecular sciences	2014
Nonalcoholic Fatty Liver Disease/Non-Alcoholic Steatohepatitis in Childhood: Endocrine-Metabolic “Mal-Programming” S Manti, C Romano, V Chirico, M Filippelli, C Cuppari, I Loddo, C Salpietro, T Arrigo	Hepatitis Monthly	2014
Sterol Regulatory Element-Binding Proteins Are Regulators of the Rat Thyroid Peroxidase Gene in Thyroid Cells C Rauer, R Ringseis, S Rothe, G Wen, K Eder, M Plateroti	PloS one	2014
Fermentation of Soy Milk via Lactobacillus plantarum Improves Dysregulated Lipid Metabolism in Rats on a High Cholesterol Diet Y Kim, S Yoon, SB Lee, HW Han, H Oh, WJ Lee, SM Lee, JM Lobaccaro	PloS one	2014
Maternal Magnesium Deficiency in Mice Leads to Maternal Metabolic Dysfunction And Altered Lipid Metabolism with Fetal Growth Restriction M Gupta, MH Solanki, PK Chatterjee, X Xue, A Roman, N Desai, B Rochelson, CN Metz	Molecular Medicine	2014
Deciphering the roles of the constitutive androstane receptor in energy metabolism J Yan, B Chen, J Lu, W Xie	Acta Pharmacologica Sinica	2014
Transcriptional fingerprints of antigen-presenting cell subsets in the human vaginal mucosa and skin reflect tissue-specific immune microenvironments D Duluc, R Banchereau, J Gannevat, L Thompson-Snipes, JP Blanck, S Zurawski, G Zurawski, S Hong, J Rossello-Urgell, V Pascual, N Baldwin, J Stecher, M Carley, M Boreham, SK Oh	Genome Medicine	2014
Nutrient deprivation induces Î±-synuclein aggregation through endoplasmic reticulum stress response and SREBP2 pathway P Jiang, M Gan, WL Lin, SH Yen	Frontiers in aging neuroscience	2014
Deficiency in Nrf2 transcription factor decreases adipose tissue mass and hepatic lipid accumulation in leptin-deficient mice: Nrf2 Deficiency Exacerbates Metabolic Syndrome J Xu, AC Donepudi, VR More, SR Kulkarni, L Li, L Guo, B Yan, T Chatterjee, N Weintraub, AL Slitt	Obesity	2014
A novel polymorphism of the GP78 gene is associated with coronary artery disease in Han population in China E Cha, ZY Fu, YT Ma, Q Zhu, X Xie, F Liu	Lipids in Health and Disease	2014
Effects of Long-Term Supplementation of Blue-Green Algae on Lipid Metabolism in C57BL/6J mice JY Lee	Journal of Nutritional Health & Food Science	2014
Forward Genetic Screening for Regulators Involved in Cholesterol Synthesis Using Validation-Based Insertional Mutagenesis W Jiang, JJ Tang, HH Miao, YX Qu, J Qin, J Xu, J Yang, BL Li, BL Song, H Wanjin	PloS one	2014
GW4064, a farnesoid X receptor agonist, upregulates adipokine expression in preadipocytes and HepG2 cells XM Xin	World journal of gastroenterology : WJG	2014
Insulin resistance and liver steatosis in chronic hepatitis C infection genotype 3 L Abenavoli	World journal of gastroenterology : WJG	2014
MicroRNAs as controlled systems and controllers in non-alcoholic fatty liver disease N Panera	World journal of gastroenterology : WJG	2014
Transcriptomic Analysis Unveils Correlations between Regulative Apoptotic Caspases and Genes of Cholesterol Homeostasis in Human Brain R Picco, A Tomasella, F Fogolari, C Brancolini, B Zhivotovsky	PloS one	2014
Effects of miR-33a-5P on ABCA1/G1-Mediated Cholesterol Efflux under Inflammatory Stress in THP-1 Macrophages M Mao, H Lei, Q Liu, Y Chen, L Zhao, Q Li, S Luo, Z Zuo, Q He, W Huang, N Zhang, C Zhou, XZ Ruan, A Cignarella	PloS one	2014
Deletion of ELOVL6 blocks the synthesis of oleic acid but does not prevent the development of fatty liver or insulin resistance YA Moon, CR Ochoa, MA Mitsche, RE Hammer, JD Horton	Journal of lipid research	2014
Function of SREBP1 in the Milk Fat Synthesis of Dairy Cow Mammary Epithelial Cells N Li, F Zhao, C Wei, M Liang, N Zhang, C Wang, QZ Li, XJ Gao	International journal of molecular sciences	2014
Liver X Receptor Regulation of Thyrotropin-Releasing Hormone Transcription in Mouse Hypothalamus Is Dependent on Thyroid Status R Ghaddab-Zroud, I Seugnet, KR Steffensen, BA Demeneix, MS Clerget-Froidevaux, H Guillou	PloS one	2014
Long-term therapeutic silencing of miR-33 increases circulating triglyceride levels and hepatic lipid accumulation in mice L Goedeke, A Salerno, CM Ramirez, L Guo, RM Allen, X Yin, SR Langley, C Esau, A Wanschel, EA Fisher, Y Suarez, A Baldan, M Mayr, C Fernandez-Hernando	EMBO Molecular Medicine	2014
The Combined Effect of Azithromycin and Insulin-Like Growth Factor-1 on Cultured Human Meibomian Gland Epithelial Cells Y Liu, J Ding	Investigative ophthalmology & visual science	2014
Sterol Regulatory Element-binding Protein-1 (SREBP-1) Is Required to Regulate Glycogen Synthesis and Gluconeogenic Gene Expression in Mouse Liver R Ruiz, V Jideonwo, M Ahn, S Surendran, VS Tagliabracci, Y Hou, A Gamble, J Kerner, JM Irimia-Dominguez, MA Puchowicz, A DePaoli-Roach, C Hoppel, P Roach, N Morral	The Journal of biological chemistry	2014
The brown fat–enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuation of hepatic lipogenesis GX Wang, XY Zhao, ZX Meng, M Kern, A Dietrich, Z Chen, Z Cozacov, D Zhou, AL Okunade, X Su, S Li, M Blüher, JD Lin	Nature Medicine	2014
Dietary Cholesterol Promotes Adipocyte Hypertrophy and Adipose Tissue Inflammation in Visceral, but Not in Subcutaneous, Fat in Monkeys S Chung, H Cuffe, SM Marshall, AL McDaniel, JH Ha, K Kavanagh, C Hong, P Tontonoz, RE Temel, JS Parks	Arteriosclerosis, thrombosis, and vascular biology	2014
Identification of genes whose expression is altered by obesity throughout the arterial tree J Padilla, NT Jenkins, PK Thorne, JS Martin, RS Rector, JW Davis, MH Laughlin	Physiological genomics	2014
Regulation of Lipogenic Gene Expression by Lysine-specific Histone Demethylase-1 (LSD1) A Abdulla, Y Zhang, FN Hsu, AM Xiaoli, X Zhao, ES Yang, JY Ji, F Yang	The Journal of biological chemistry	2014
Lipid Regulation in Lipodystrophy Versus the Obesity-Associated Metabolic Syndrome: The Dissociation of HDL-C and Triglycerides J Joseph, RD Shamburek, EK Cochran, P Gorden, RJ Brown	The Journal of clinical endocrinology and metabolism	2014
Thyroid hormone responsive protein Spot14 enhances catalysis of fatty acid synthase in lactating mammary epithelium MC Rudolph, EA Wellberg, AS Lewis, KL Terrell, AL Merz, NK Maluf, NJ Serkova, SM Anderson	Journal of lipid research	2014
Fatostatin Displays High Antitumor Activity in Prostate Cancer by Blocking SREBP-Regulated Metabolic Pathways and Androgen Receptor Signaling X Li, YT Chen, P Hu, WC Huang	Molecular cancer therapeutics	2014
Targeted deletion of C1q/TNF-related protein 9 increases food intake, decreases insulin sensitivity, and promotes hepatic steatosis in mice Z Wei, X Lei, PS Petersen, S Aja, GW Wong	American journal of physiology. Endocrinology and metabolism	2014
Pathways of cholesterol homeostasis in mouse retina responsive to dietary and pharmacologic treatments W Zheng, N Mast, A Saadane, IA Pikuleva	Journal of lipid research	2014
Hepatic insulin receptor deficiency impairs the SREBP-2 response to feeding and statins J Miao, JT Haas, P Manthena, Y Wang, E Zhao, B Vaitheesvaran, IJ Kurland, SB Biddinger	Journal of lipid research	2014
MicroRNA-185 regulates expression of lipid metabolism genes and improves insulin sensitivity in mice with non-alcoholic fatty liver disease Xiao Chen Wang, Xiao Rong Zhan, Xin Yu Li, Jun Jie Yu, Xiao Min Liu	World Journal of Gastroenterology	2014
Disruption of ldlr causes increased LDL-c and vascular lipid accumulation in a zebrafish model of hypercholesterolemia EA O'Hare, X Wang, ME Montasser, YP Chang, BD Mitchell, NA Zaghloul	Journal of lipid research	2014
Inhibition of microRNA-24 expression in liver prevents hepatic lipid accumulation and hyperlipidemia: NG ET AL R Ng, H Wu, H Xiao, X Chen, H Willenbring, CJ Steer, G Song	Hepatology	2014
Expression of miR-33 from an SREBF2 Intron Targets the FTO Gene in the Chicken F Shao, X Wang, J Yu, H Jiang, B Zhu, Z Gu, A Wijnen	PloS one	2014
Epithelial SCAP/INSIG/SREBP Signaling Regulates Multiple Biological Processes during Perinatal Lung Maturation JP Bridges, A Schehr, Y Wang, L Huo, V Besnard, M Ikegami, JA Whitsett, Y Xu, D Hartl	PloS one	2014
Overactivation of Intestinal SREBP2 in Mice Increases Serum Cholesterol K Ma, P Malhotra, V Soni, O Hedroug, F Annaba, A Dudeja, L Shen, JR Turner, EA Khramtsova, S Saksena, PK Dudeja, RK Gill, WA Alrefai, JM Lobaccaro	PloS one	2014
Single Nucleotide Polymorphism of SREBF-1 Gene Associated with an Increased Risk of Endometrial Cancer in Chinese Women CP Qiu, QT Lv, S Dongol, C Wang, J Jiang, KH Baek	PloS one	2014
Dual Mode Action of Mangiferin in Mouse Liver under High Fat Diet J Lim, Z Liu, P Apontes, D Feng, JE Pessin, AA Sauve, RH Angeletti, Y Chi, JA Chowen	PloS one	2014
Deficiency of the Transcriptional Repressor B Cell Lymphoma 6 (Bcl6) Is Accompanied by Dysregulated Lipid Metabolism CR LaPensee, G Lin, AL Dent, J Schwartz, X Chen	PloS one	2014
IL-33 treatment attenuated diet-induced hepatic steatosis but aggravated hepatic fibrosis Y Gao, Y Liu, M Yang, X Guo, M Zhang, H Li, J Li, J Zhao	Oncotarget	2014
Oxysterols synergize with statins by inhibiting SREBP-2 in ovarian cancer cells C Casella, DH Miller, K Lynch, AS Brodsky	Gynecologic Oncology	2014
Balanced mTORC1 Activity in Oligodendrocytes Is Required for Accurate CNS Myelination F Lebrun-Julien, L Bachmann, C Norrmen, M Trotzmuller, H Kofeler, MA Ruegg, MN Hall, U Suter	The Journal of neuroscience : the official journal of the Society for Neuroscience	2014
Targeting SREBP-1-driven lipid metabolism to treat cancer. Guo D, Bell EH, Mischel P, Chakravarti A	Current pharmaceutical design	2014
Phosphorylation of sterol regulatory element binding protein-1a by protein kinase A (PKA) regulates transcriptional activity. Dong Q, Giorgianni F, Deng X, Beranova-Giorgianni S, Bridges D, Park EA, Raghow R, Elam MB	Biochemical and Biophysical Research Communications	2014
In vitro exposure to copper influences lipid metabolism in hepatocytes from grass carp (Ctenopharyngodon idellus). Zhu QL, Luo Z, Zhuo MQ, Tan XY, Sun LD, Zheng JL, Chen QL	Fish Physiology and Biochemistry	2014
PIASy-mediated sumoylation of SREBP1c regulates hepatic lipid metabolism upon fasting signaling GY Lee, H Jang, JH Lee, JY Huh, S Choi, J Chung, JB Kim	Molecular and cellular biology	2013
Mice lacking ANGPTL8 (Betatrophin) manifest disrupted triglyceride metabolism without impaired glucose homeostasis Y Wang, F Quagliarini, V Gusarova, J Gromada, DM Valenzuela, JC Cohen, HH Hobbs	Proceedings of the National Academy of Sciences	2013
Comprehensive Physiology BJ Wilkins, M Pack	Comprehensive Physiology	2013
Reprogramming of lysosomal gene expression by interleukin-4 and Stat6 LM Brignull, Z Czimmerer, H Saidi, B Daniel, I Villela, NW Bartlett, SL Johnston, LB Meira, L Nagy, A Nohturfft	BMC Genomics	2013
Ion-current-based Proteomic Profiling of the Retina in a Rat Model of Smith-Lemli-Opitz Syndrome C Tu, J Li, X Jiang, LG Sheflin, BA Pfeffer, M Behringer, SJ Fliesler, J Qu	Molecular & cellular proteomics : MCP	2013
MicroRNA 33 Regulates Glucose Metabolism CM Ramirez, L Goedeke, N Rotllan, JH Yoon, D Cirera-Salinas, JA Mattison, Y Suarez, R de Cabo, M Gorospe, C Fernandez-Hernando	Molecular and cellular biology	2013
The fat side of prostate cancer G Zadra, C Photopoulos, M Loda	Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids	2013
Viperin Regulates Cellular Lipid Metabolism during Human Cytomegalovirus Infection JY Seo, P Cresswell, K Früh	PLoS pathogens	2013
Mechanisms of hepatic triglyceride accumulation in non-alcoholic fatty liver disease Y Kawano, DE Cohen	Journal of Gastroenterology	2013
S-nitrosylation of ARH is required for LDL uptake by the LDL receptor Z Zhao, S Pompey, H Dong, J Weng, R Garuti, P Michaely	Journal of lipid research	2013
Diagnosis and Management of Familial Dyslipoproteinemias PO Kwiterovich	Current Cardiology Reports	2013
Knockout of mouse Cyp3a gene enhances synthesis of cholesterol and bile acid in the liver M Hashimoto, K Kobayashi, M Watanabe, Y Kazuki, S Takehara, A Inaba, S Nitta, N Senda, M Oshimura, K Chiba	Journal of lipid research	2013
Hepatic Isoprenoid Metabolism in a Rat Model of Smith-Lemli-Opitz Syndrome RK Keller, DA Mitchell, CC Goulah, SJ Fliesler	Lipids	2013
From evolution to revolution: miRNAs as pharmacological targets for modulating cholesterol efflux and reverse cholesterol transport A Dávalos, C Fernández-Hernando	Pharmacological Research	2013
Mediating lipid biosynthesis: Implications for cardiovascular disease Xiaoli, Fajun Yang	Trends in Cardiovascular Medicine	2013
Influence of genotype on the modulation of gene and protein expression by n-3 LC-PUFA in rats E Boschetti, MD Nunzio, F Danesi, V Tugnoli, A Bordoni	Genes & Nutrition	2013
Hepatitis C virus infection activates an innate pathway involving IKK-α in lipogenesis and viral assembly Q Li, V Pène, S Krishnamurthy, H Cha, TJ Liang	Nature Medicine	2013
Endoplasmic reticulum stress leads to lipid accumulation through upregulation of SREBP-1c in normal hepatic and hepatoma cells D Fang, Y Wan, W Shen, J Cao, Z Sun, H Yu, Q Zhang, W Cheng, J Chen, B Ning	Molecular and Cellular Biochemistry	2013
Cellular Fatty Acid Metabolism and Cancer E Currie, A Schulze, R Zechner, TC Walther, RV Farese	Cell Metabolism	2013
Role of Mitochondria in Alcoholic Liver Disease C García-Ruiz, N Kaplowitz, JC Fernandez-Checa	Current Pathobiology Reports	2013
Potential mechanisms of atypical antipsychotic-induced hypertriglyceridemia H Yan, JD Chen, XY Zheng	Psychopharmacology	2013
Lipid metabolism emerges as a promising target for malignant glioma therapy D Guo, EH Bell, A Chakravarti	CNS Oncology	2013
Subverting sterols: rerouting an oxysterol-signaling pathway to promote tumor growth AG York, SJ Bensinger	Journal of Experimental Medicine	2013
Leptin Engages a Hypothalamic Neurocircuitry to Permit Survival in the Absence of Insulin T Fujikawa, ED Berglund, VR Patel, G Ramadori, CR Vianna, L Vong, F Thorel, S Chera, PL Herrera, BB Lowell, JK Elmquist, P Baldi, R Coppari	Cell Metabolism	2013
Tumor-suppressive effects of CDK8 in endometrial cancer cells W Gu, C Wang, W Li, FN Hsu, L Tian, J Zhou, C Yuan, XJ Xie, T Jiang, S Addya, Y Tai, B Kong, JY Ji	Cell cycle (Georgetown, Tex.)	2013
Amyloid precursor protein controls cholesterol turnover needed for neuronal activity N Pierrot, D Tyteca, L D'auria, I Dewachter, P Gailly, A Hendrickx, B Tasiaux, LE Haylani, N Muls, F N'kuli, A Laquerrière, JB Demoulin, D Campion, JP Brion, PJ Courtoy, P Kienlen-Campard, JN Octave	EMBO Molecular Medicine	2013
Adaptive changes of the Insig1/SREBP1/SCD1 set point help adipose tissue to cope with increased storage demands of obesity S Carobbio, RM Hagen, CJ Lelliott, M Slawik, G Medina-Gomez, CY Tan, A Sicard, HJ Atherton, N Barbarroja, M Bjursell, M Bohlooly-Y, S Virtue, A Tuthill, E Lefai, M Laville, T Wu, RV Considine, H Vidal, D Langin, M Oresic, FJ Tinahones, JM Fernandez-Real, JL Griffin, JK Sethi, M López, A Vidal-Puig	Diabetes	2013
MicroRNA-33 regulates sterol regulatory element-binding protein 1 expression in mice T Horie, T Nishino, O Baba, Y Kuwabara, T Nakao, M Nishiga, S Usami, M Izuhara, N Sowa, N Yahagi, H Shimano, S Matsumura, K Inoue, H Marusawa, T Nakamura, K Hasegawa, N Kume, M Yokode, T Kita, T Kimura, K Ono	Nature Communications	2013
Hepatic SREBP-2 and cholesterol biosynthesis are regulated by FoxO3 and Sirt6 R Tao, X Xiong, RA DePinho, CX Deng, XC Dong	Journal of lipid research	2013
Metabolite and transcriptome analysis during fasting suggest a role for the p53-Ddit4 axis in major metabolic tissues M Schupp, F Chen, ER Briggs, S Rao, HJ Pelzmann, AR Pessentheiner, JG Bogner-Strauss, MA Lazar, D Baldwin, A Prokesch	BMC Genomics	2013
HNRNPA1 regulates HMGCR alternative splicing and modulates cellular cholesterol metabolism CY Yu, E Theusch, K Lo, LM Mangravite, D Naidoo, M Kutilova, MW Medina	Human Molecular Genetics	2013
Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis MD Huber, PW Vesely, K Datta, L Gerace	The Journal of Cell Biology	2013
Roles of Vitamin A Metabolism in the Development of Hepatic Insulin Resistance G Chen	ISRN Hepatology	2013
Keap1 knockdown increases markers of metabolic syndrome after long-term high fat diet feeding VR More, J Xu, PC Shimpi, C Belgrave, JP Luyendyk, M Yamamoto, AL Slitt	Free radical biology & medicine	2013
Exploration of the Hypothalamic-Pituitary-Adrenal Axis to Improve Animal Welfare by Means of Genetic Selection: Lessons from the South African Merino D Hough, P Swart, S Cloete	Animals	2013
Lipopolysaccharides accelerate hepatic steatosis in the development of nonalcoholic fatty liver disease in Zucker rats S Fukunishi, T Sujishi, A Takeshita, H Ohama, Y Tsuchimoto, A Asai, Y Tsuda, K Higuchi	Journal of Clinical Biochemistry and Nutrition	2013
Conjugated and free sterols from black bean (Phaseolus vulgaris L.) seed coats as cholesterol micelle disruptors and their effect on lipid metabolism and cholesterol transport in rat primary hepatocytes RA Chávez-Santoscoy, AR Tovar, SO Serna-Saldivar, N Torres, JA Gutiérrez-Uribe	Genes & Nutrition	2013
Tumor metabolism of malignant gliomas P Ru, TM Williams, A Chakravarti, D Guo	Cancers	2013
Enhanced SCAP glycosylation by inflammation induces macrophage foam cell formation C Zhou, H Lei, Y Chen, Q Liu, LC Li, JF Moorhead, Z Varghese, XZ Ruan	PloS one	2013
Nonalcoholic fatty liver disease: molecular mechanisms for the hepatic steatosis SH Koo	Clinical and Molecular Hepatology	2013
Pro-apoptotic miRNA-128-2 modulates ABCA1, ABCG1 and RXRα expression and cholesterol homeostasis YK Adlakha, S Khanna, R Singh, VP Singh, A Agrawal, N Saini	Cell Death and Disease	2013
Cirsium brevicaule A. GRAY leaf inhibits adipogenesis in 3T3-L1 cells and C57BL/6 mice M Inafuku, RN Nugara, Y Kamiyama, I Futenma, A Inafuku, H Oku	Lipids in Health and Disease	2013
Comparison of in vivo effects of insulin on SREBP-1c activation and INSIG-1/2 in rat liver and human and rat adipose tissue G Boden, S Salehi, P Cheung, C Homko, W Song, C Loveland-Jones, S Jayarajan	Obesity	2013
Regulation of mTORC1 and its impact on gene expression at a glance M Laplante, DM Sabatini	Journal of cell science	2013
Modulation of hepatitis C virus genome encapsidation by nonstructural protein 4B Q Han, D Manna, K Belton, R Cole, KV Konan	Journal of virology	2013
Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity Y Kidani, H Elsaesser, MB Hock, L Vergnes, KJ Williams, JP Argus, BN Marbois, E Komisopoulou, EB Wilson, TF Osborne, TG Graeber, K Reue, DG Brooks, SJ Bensinger	Nature Immunology	2013
Fatty acid-regulated transcription factors in the liver DB Jump, S Tripathy, CM Depner	Annual Review of Nutrition	2013
An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity KJ Williams, JP Argus, Y Zhu, MQ Wilks, BN Marbois, AG York, Y Kidani, AL Pourzia, D Akhavan, DN Lisiero, E Komisopoulou, AH Henkin, H Soto, BT Chamberlain, L Vergnes, ME Jung, JZ Torres, LM Liau, HR Christofk, RM Prins, PS Mischel, K Reue, TG Graeber, SJ Bensinger	Cancer research	2013
Oxysterol-binding protein family I is the target of minor enviroxime-like compounds M Arita, H Kojima, T Nagano, T Okabe, T Wakita, H Shimizu	Journal of virology	2013
Histone deacetylase inhibition decreases cholesterol levels in neuronal cells by modulating key genes in cholesterol synthesis, uptake and efflux MJ Nunes, M Moutinho, MJ Gama, CM Rodrigues, E Rodrigues	PloS one	2013
Point mutation in luminal loop 7 of Scap protein blocks interaction with loop 1 and abolishes movement to Golgi Y Zhang, M Motamed, J Seemann, MS Brown, JL Goldstein	The Journal of biological chemistry	2013
Peripheral blood mononuclear cells: a potential source of homeostatic imbalance markers associated with obesity development P Oliver, B Reynés, A Caimari, A Palou	Pflügers Archiv - European Journal of Physiology	2013
Transcriptional control of hepatic lipid metabolism by SREBP and ChREBP X Xu, JS So, JG Park, AH Lee	Seminars in liver disease	2013
The Structural Basis of Cholesterol Accessibility in Membranes BN Olsen, AA Bielska, T Lee, MD Daily, DF Covey, PH Schlesinger, NA Baker, DS Ory	Biophysical Journal	2013
Disruption of the cereblon gene enhances hepatic AMPK activity and prevents high-fat diet-induced obesity and insulin resistance in mice KM Lee, SJ Yang, YD Kim, YD Choi, JH Nam, CS Choi, HS Choi, CS Park	Diabetes	2013
MicroRNA-33a mediates the regulation of high mobility group AT-hook 2 gene (HMGA2) by thyroid transcription factor 1 (TTF-1/NKX2-1) SJ Rice, SC Lai, LW Wood, KR Helsley, EA Runkle, MM Winslow, D Mu	The Journal of biological chemistry	2013
SCAP gene polymorphisms decrease the risk of nonalcoholic fatty liver disease in females with metabolic syndrome S Sun, M Wang, H Song, T Wu, H Wei, S He, Z Ding, G Ji	Journal of Genetics	2013
Topics in transcriptional control of lipid metabolism: from transcription factors to gene-promoter polymorphisms WG Bergen, DD Burnett	Journal of genomics	2013
The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation V Sorrentino, JK Nelson, E Maspero, AR Marques, L Scheer, S Polo, N Zelcer	Journal of lipid research	2013
cAMP-stimulated transcription of DGKθ requires steroidogenic factor 1 and sterol regulatory element binding protein 1 K Cai, MB Sewer	Journal of lipid research	2013
Activation of Sterol Regulatory Element Binding Protein and NLRP3 Inflammasome in Atherosclerotic Lesion Development in Diabetic Pigs Y Li, S Xu, B Jiang, RA Cohen, M Zang, K Jandeleit-Dahm	PloS one	2013
Association between SREBP-1 gene expression in mammary gland and milk fat yield in Sarda breed sheep V Carcangiu, MC Mura, C Daga, S Luridiana, S Bodano, GA Sanna, ML Diaz, G Cosso	Meta Gene	2013
The complexity of thyroid transcription factor 1 with both pro- and anti-oncogenic activities D Mu	The Journal of biological chemistry	2013
Regulation of cholesterol and bile acid homeostasis by the CYP7A1/SREBP2/miR-33a axis T Li, JM Francl, S Boehme, JY Chiang	Hepatology	2013
Map4k4 suppresses Srebp-1 and adipocyte lipogenesis independent of JNK signaling Laura V Danai, Adilson Guilherme, Kalyani V Guntur, Juerg Straubhaar, Sarah M Nicoloro, Michael P Czech		2013
Cross-talk between hypoxia and insulin signaling through Phd3 regulates hepatic glucose and lipid metabolism and ameliorates diabetes CM Taniguchi, EC Finger, AJ Krieg, C Wu, AN Diep, EL LaGory, K Wei, LM McGinnis, J Yuan, CJ Kuo, AJ Giaccia		2013
Key intestinal genes involved in lipoprotein metabolism are downregulated in dyslipidemic men with insulin resistance P Couture, AJ Tremblay, I Kelly, V Lemelin, A Droit, B Lamarche	Journal of lipid research	2013
Phosphorylation and Recruitment of BAF60c in Chromatin Remodeling for Lipogenesis in Response to Insulin Y Wang, RH Wong, T Tang, CS Hudak, D Yang, RE Duncan, HS Sul	Molecular Cell	2013
Insig Proteins Mediate Feedback Inhibition of Cholesterol Synthesis in the Intestine MR McFarlane, G Liang, LJ Engelking	The Journal of biological chemistry	2013
Lipoprotein Metabolism, Dyslipidemia, and Nonalcoholic Fatty Liver Disease D Cohen, E Fisher	Seminars in liver disease	2013
Adaptive responses by mouse fetus to a maternal HLE diet by downregulating SREBP1: a microarray- and bio-analytic-based study HL Yu, HT Miao, LF Gao, L Li, YD Xi, SP Nie, R Xiao	Journal of lipid research	2013
Autophagy Deficiency by Hepatic FIP200 Deletion Uncouples Steatosis From Liver Injury in NAFLD D Ma, MM Molusky, J Song, CR Hu, F Fang, C Rui, AV Mathew, S Pennathur, F Liu, JX Cheng, JL Guan, JD Lin	Molecular Endocrinology	2013
Glycerol-3-phosphate Acyltransferase (GPAT)-1, but Not GPAT4, Incorporates Newly Synthesized Fatty Acids into Triacylglycerol and Diminishes Fatty Acid Oxidation AA Wendel, DE Cooper, OR Ilkayeva, DM Muoio, RA Coleman	The Journal of biological chemistry	2013
The Increasingly Complex Mechanism of HMG-CoA Reductase BE Haines, O Wiest, CV Stauffacher	Accounts of Chemical Research	2013
Casein Kinase 1 Regulates Sterol Regulatory Element-binding Protein (SREBP) to Control Sterol Homeostasis RT Brookheart, CY Lee, PJ Espenshade	The Journal of biological chemistry	2013
Glycogen Synthase Kinase 3 Inactivation Induces Cell Senescence through Sterol Regulatory Element Binding Protein 1-Mediated Lipogenesis in Chang Cells YM Kim, I Song, YH Seo, G Yoon	Endocrinology and Metabolism	2013
Signal integration by mTORC1 coordinates nutrient input with biosynthetic output CC Dibble, BD Manning	Nature Cell Biology	2013
Upregulation of fatty acid synthesis and the suppression of hepatic triglyceride lipase as a direct cause of hereditary postprandial hypertriglyceridemia in rabbits N Fukuda, T Ito, K Ohwada, J Fujii	Journal of Clinical Biochemistry and Nutrition	2013
Hexavalent Chromium-induced Alteration of Proteomic Landscape in Human Skin Fibroblast Cells L Guo, Y Xiao, Y Wang	Journal of Proteome Research	2013
Diets Containing Sea Cucumber (Isostichopus badionotus) Meals Are Hypocholesterolemic in Young Rats L Olivera-Castillo, A Davalos, G Grant, N Valadez-Gonzalez, J Montero, HA Barrera-Perez, Y Chim-Chi, MA Olvera-Novoa, V Ceja-Moreno, P Acereto-Escoffie, J Rubio-Piña, R Rodriguez-Canul, JM Lobaccaro	PloS one	2013
Dietary Fat Content and Fiber Type Modulate Hind Gut Microbial Community and Metabolic Markers in the Pig H Yan, R Potu, H Lu, VV de Almeida, T Stewart, D Ragland, A Armstrong, O Adeola, CH Nakatsu, KM Ajuwon, AM Ibekwe	PloS one	2013
PKR-Like Endoplasmic Reticulum Kinase Is Necessary for Lipogenic Activation during HCMV Infection Y Yu, FJ Pierciey, TG Maguire, JC Alwine, B Damania	PLoS pathogens	2013
Mutations in LMNA Modulate the Lamin A - Nesprin-2 Interaction and Cause LINC Complex Alterations L Yang, M Munck, K Swaminathan, LE Kapinos, AA Noegel, S Neumann, A Lewin	PloS one	2013
Chronic Administration of Proanthocyanidins or Docosahexaenoic Acid Reversess the Increase of miR-33a and miR-122 in Dyslipidemic Obese Rats L Baselga-Escudero, A Arola-Arnal, A Pascual-Serrano, A Ribas-Latre, E Casanova, MJ Salvadó, L Arola, C Blade, WH Schunck	PloS one	2013
Bovine Mammary Gene Expression Profiling during the Onset of Lactation Y Gao, X Lin, K Shi, Z Yan, Z Wang, MF Pas	PloS one	2013
Anti-Hyperlipidemic Effects and Potential Mechanisms of Action of the Caffeoylquinic Acid-Rich Pandanus tectorius Fruit Extract in Hamsters Fed a High Fat-Diet X Zhang, C Wu, H Wu, L Sheng, Y Su, X Zhang, H Luan, G Sun, X Sun, Y Tian, Y Ji, P Guo, X Xu, A Motta	PloS one	2013
Sterol Regulatory Element-Binding Proteins Are Regulators of the NIS Gene in Thyroid Cells R Ringseis, C Rauer, S Rothe, DK Gessner, LM Schütz, S Luci, G Wen, K Eder	Molecular Endocrinology	2013
Differential Regulation of Gene Expression by LXRs in Response to Macrophage Cholesterol Loading ID Ignatova, J Angdisen, E Moran, IG Schulman	Molecular Endocrinology	2013
A Regulatory Role for MicroRNA 33* in Controlling Lipid Metabolism Gene Expression L Goedeke, FM Vales-Lara, M Fenstermaker, D Cirera-Salinas, A Chamorro-Jorganes, CM Ramirez, JA Mattison, R de Cabo, Y Suarez, C Fernandez-Hernando	Molecular and cellular biology	2013
Ankyrin Repeat Domain Protein 2 and Inhibitor of DNA Binding 3 Cooperatively Inhibit Myoblast Differentiation by Physical Interaction JS Mohamed, MA Lopez, GA Cox, AM Boriek	The Journal of biological chemistry	2013
Caffeine attenuates lipid accumulation via activation of AMP-activated protein kinase signaling pathway in HepG2 cells Quan HY, Kim DY, Chung SH	BMB Reports	2013
Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover Robert H. Unger, Alan Cherrington	Journal of Clinical Investigation	2012
Central Role of SREBP-2 in the Pathogenesis of Osteoarthritis F Kostopoulou, V Gkretsi, KN Malizos, D Iliopoulos, P Oikonomou, L Poultsides, A Tsezou	PloS one	2012
A role for protein inhibitor of activated STAT1 (PIAS1) in lipogenic regulation through SUMOylation-independent suppression of liver X receptors Y Zhang, Z Gan, P Huang, L Zhou, T Mao, M Shao, X Jiang, Y Chen, H Ying, M Cao, J Li, J Li, WJ Zhang, L Yang, Y Liu	The Journal of biological chemistry	2012
Hepatic ABC transporters and triglyceride metabolism : JS Parks, S Chung, GS Shelness	Current Opinion in Lipidology	2012
Atypical antipsychotics alter cholesterol and fatty acid metabolism in vitro A Canfrán-Duque, ME Casado, O Pastor, J Sánchez-Wandelmer, G la Peña, M Lerma, P Mariscal, F Bracher, MA Lasunción, R Busto	Journal of lipid research	2012
Hypomorphic sialidase expression decreases serum cholesterol by downregulation of VLDL production in mice A Yang, G Gyulay, M Mitchell, E White, BL Trigatti, SA Igdoura	Journal of lipid research	2012
RXR Partial Agonist CBt-PMN Exerts Therapeutic Effects on Type 2 Diabetes without the Side Effects of RXR Full Agonists H Kakuta, N Yakushiji, R Shinozaki, F Ohsawa, S Yamada, Y Ohta, K Kawata, M Nakayama, M Hagaya, C Fujiwara, M Makishima, S Uno, A Tai, A Maehara, M Nakayama, T Oohashi, H Yasui, Y Yoshikawa	ACS Medicinal Chemistry Letters	2012
Nuclear Receptors in Nonalcoholic Fatty Liver Disease JA López-Velázquez, LD Carrillo-Córdova, NC Chávez-Tapia, M Uribe, N Méndez-Sánchez	Journal of Lipids	2012
Hepatic FoxO1 Integrates Glucose Utilization and Lipid Synthesis through Regulation of Chrebp O-Glycosylation Y Ido-Kitamura, T Sasaki, M Kobayashi, HJ Kim, YS Lee, O Kikuchi, H Yokota-Hashimoto, K Iizuka, D Accili, T Kitamura	PloS one	2012
Resveratrol as a calorie restriction mimetic: therapeutic implications JH Chung, V Manganiello, JR Dyck	Trends in Cell Biology	2012
Leptin revisited: its mechanism of action and potential for treating diabetes R Coppari, C Bjørbæk	Nature Reviews Drug Discovery	2012
Knockout of SOD1 alters murine hepatic glycolysis, gluconeogenesis, and lipogenesis L Wang, Z Jiang, XG Lei	Free radical biology & medicine	2012
A Common Thread Connects Antidiabetic Effects of Multiple Nuclear Receptors DD Moore	Cell Metabolism	2012
Maturation and Activity of Sterol Regulatory Element Binding Protein 1 Is Inhibited by Acyl-CoA Binding Domain Containing 3 Y Chen, V Patel, S Bang, N Cohen, J Millar, SF Kim, H Waki	PloS one	2012
Enhanced Fatty Acid Flux Triggered by Adiponectin Overexpression S Shetty, MA Ramos-Roman, YR Cho, J Brown, J Plutzky, ES Muise, JD Horton, PE Scherer, EJ Parks	Endocrinology	2012
Non-Alcoholic Fatty Liver Disease: The Bile Acid-Activated Farnesoid X Receptor as an Emerging Treatment Target M Fuchs	Journal of Lipids	2012
Ablation of Iqgap2 protects from diet-induced hepatic steatosis due to impaired fatty acid uptake CS Chiariello, JF LaComb, WF Bahou, VA Schmidt	Regulatory Peptides	2012
Cholesterol-lowering Action of BNA-based Antisense Oligonucleotides Targeting PCSK9 in Atherogenic Diet-induced Hypercholesterolemic Mice T Yamamoto, M Harada-Shiba, M Nakatani, S Wada, H Yasuhara, K Narukawa, K Sasaki, MA Shibata, H Torigoe, T Yamaoka, T Imanishi, S Obika	Molecular Therapy — Nucleic Acids	2012
NAFLD, Estrogens, and Physical Exercise: The Animal Model JM Lavoie, A Pighon	Journal of nutrition and metabolism	2012
Sirtuins mediate mammalian metabolic responses to nutrient availability A Chalkiadaki, L Guarente	Nature Reviews Endocrinology	2012
Dietary restriction, caloric value and the accumulation of hepatic fat LP Moura, GA Figueredo, NO Bertolini, M Ceccato, JR Pereira, AC Sponton, MA de Mello	Lipids in Health and Disease	2012
Pharmacologic ER Stress Induces Non-alcoholic Steatohepatitis in an Animal Model JS Lee, Z Zheng, R Mendez, SW Ha, Y Xie, K Zhang	Toxicology Letters	2012
Sirtuins as regulators of metabolism and healthspan RH Houtkooper, E Pirinen, J Auwerx	Nature Reviews Molecular Cell Biology	2012
The role of CREB-H transcription factor in triglyceride metabolism : AH Lee	Current Opinion in Lipidology	2012
MicroRNAs in metabolism and metabolic disorders V Rottiers, AM Näär	Nature Reviews Molecular Cell Biology	2012
Regulation of lipid stores and metabolism by lipophagy K Liu, MJ Czaja	Cell Death and Differentiation	2012
Genome-wide localization and expression profiling establish Sp2 as a sequence-specific transcription factor regulating vitally important genes G Terrados, F Finkernagel, B Stielow, D Sadic, J Neubert, O Herdt, M Krause, M Scharfe, M Jarek, G Suske	Nucleic Acids Research	2012
Adropin Deficiency Is Associated With Increased Adiposity and Insulin Resistance KG Kumar, J Zhang, S Gao, J Rossi, OP McGuinness, HH Halem, MD Culler, RL Mynatt, AA Butler	Obesity	2012
Therapeutic potential of cyclodextrins in the treatment of Niemann–Pick type C disease B Liu	Clinical Lipidology	2012
Diet high in fat and sucrose induces rapid onset of obesity-related metabolic syndrome partly through rapid response of genes involved in lipogenesis, insulin signalling and inflammation in mice ZH Yang, H Miyahara, J Takeo, M Katayama	Diabetology & metabolic syndrome	2012
Lipid-Regulating Effect of Traditional Chinese Medicine: Mechanisms of Actions WJ Bei, J Guo, HY Wu, Y Cao	Evidence-based complementary and alternative medicine : eCAM	2012
Differential mRNA expression of seven genes involved in cholesterol metabolism and transport in the liver of atherosclerosis-susceptible and -resistant Japanese quail strains X Li, P Schulte, DV Godin, KM Cheng	Genetics, Selection, Evolution : GSE	2012
Liver-Specific Expression of Transcriptionally Active SREBP-1c Is Associated with Fatty Liver and Increased Visceral Fat Mass B Knebel, J Haas, S Hartwig, S Jacob, C Köllmer, U Nitzgen, D Muller-Wieland, J Kotzka	PloS one	2012
Aldo-Keto Reductases 1B in Endocrinology and Metabolism E Pastel, JC Pointud, F Volat, A Martinez, AM Lefrançois-Martinez	Frontiers in pharmacology	2012
Cholesterol Synthesis Is Associated with Hepatic Lipid Content and Dependent on Fructose/Glucose Intake in Healthy Humans G Silbernagel, D Lütjohann, J Machann, S Meichsner, K Kantartzis, F Schick, HU Häring, N Stefan, A Fritsche	Experimental Diabetes Research	2012
Ursolic Acid Increases Skeletal Muscle and Brown Fat and Decreases Diet-Induced Obesity, Glucose Intolerance and Fatty Liver Disease SD Kunkel, CJ Elmore, KS Bongers, SM Ebert, DK Fox, MC Dyle, SA Bullard, CM Adams	PloS one	2012
Preventing Phosphorylation of Sterol Regulatory Element-Binding Protein 1a by MAP-Kinases Protects Mice from Fatty Liver and Visceral Obesity J Kotzka, B Knebel, J Haas, L Kremer, S Jacob, S Hartwig, U Nitzgen, D Muller-Wieland	PloS one	2012
In ovo leptin administration affects hepatic lipid metabolism and microRNA expression in newly hatched broiler chickens Y Hu, R Zhang, Y Zhang, J Li, R Grossmann, R Zhao	Journal of Animal Science and Biotechnology	2012
Exploitation of Lipid Components by Viral and Host Proteins for Hepatitis C Virus Infection K Moriishi, Y Matsuura	Frontiers in microbiology	2012
Ginsenoside Rg3 Reduces Lipid Accumulation with AMP-Activated Protein Kinase (AMPK) Activation in HepG2 Cells S Lee, MS Lee, CT Kim, IH Kim, Y Kim	International journal of molecular sciences	2012
A Systems Biology Approach to Deciphering the Etiology of Steatosis Employing Patient-Derived Dermal Fibroblasts and iPS Cells J Jozefczuk, K Kashofer, R Ummanni, F Henjes, S Rehman, S Geenen, W Wruck, C Regenbrecht, A Daskalaki, C Wierling, P Turano, I Bertini, U Korf, K Zatloukal, HV Westerhoff, H Lehrach, J Adjaye	Frontiers in physiology	2012
Meal Time Shift Disturbs Circadian Rhythmicity along with Metabolic and Behavioral Alterations in Mice JA Yoon, DH Han, JY Noh, MH Kim, GH Son, K Kim, CJ Kim, YK Pak, S Cho	PloS one	2012
Single dose testosterone increases total cholesterol levels and induces the expression of HMG CoA Reductase N Gårevik, C Skogastierna, A Rane, L Ekström	Substance abuse treatment, prevention, and policy	2012
Effects of sterol regulatory element-binding protein (SREBP) in chickens FA Khesht, A Hassanabadi	Lipids in Health and Disease	2012
Targeting autophagy for the treatment of liver diseases HM Ni, JA Williams, H Yang, YH Shi, J Fan, WX Ding	Pharmacological Research	2012
Atypical angiopoietin-like protein that regulates ANGPTL3 F Quagliarini, Y Wang, J Kozlitina, NV Grishin, R Hyde, E Boerwinkle, DM Valenzuela, AJ Murphy, JC Cohen, HH Hobbs	Proceedings of the National Academy of Sciences	2012
INSIG2 variants, dietary patterns and metabolic risk in Samoa A Baylin, R Deka, J Tuitele, S Viali, DE Weeks, ST McGarvey	European Journal of Clinical Nutrition	2012
The multifaceted role of mTORC1 in the control of lipid metabolism SJ Ricoult, BD Manning	EMBO reports	2012
A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism MA Herman, OD Peroni, J Villoria, MR Schön, NA Abumrad, M Blüher, S Klein, BB Kahn	Nature	2012
Hepatic Steatosis in Type 1 Diabetes SE Regnell, Å Lernmark	The review of diabetic studies : RDS	2012
Kr-pok increases FASN expression by modulating the DNA binding of SREBP-1c and Sp1 at the proximal promoter BN Jeon, YS Kim, WI Choi, DI Koh, MK Kim, JH Yoon, MY Kim, B Hur, PD Paik, MW Hur	Journal of lipid research	2012
Toward a unifying hypothesis of metabolic syndrome AA Bremer, M Mietus-Snyder, RH Lustig	Pediatrics	2012
Beneficial effects of flaxseed oil and fish oil diet are through modulation of different hepatic genes involved in lipid metabolism in streptozotocin-nicotinamide induced diabetic rats PP Devarshi, NM Jangale, AE Ghule, SL Bodhankar, AM Harsulkar	Genes & Nutrition	2012
Analysis of bioactive oxysterols in newborn mouse brain by LC/MS A Meljon, S Theofilopoulos, CH Shackleton, GL Watson, NB Javitt, HJ Knölker, R Saini, E Arenas, Y Wang, WJ Griffiths	Journal of lipid research	2012
Hepatitis C virus-host interactions: Etiopathogenesis and therapeutic strategies M Hassan, D Selimovic, A El-Khattouti, H Ghozlan, Y Haikel, O Abdelkader	World Journal of Experimental Medicine	2012
Misregulation of PPAR Functioning and Its Pathogenic Consequences Associated with Nonalcoholic Fatty Liver Disease in Human Obesity LA Videla, P Pettinelli	PPAR Research	2012
The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response M Blanc, WY Hsieh, KA Robertson, KA Kropp, T Forster, G Shui, P Lacaze, S Watterson, SJ Griffiths, NJ Spann, A Meljon, S Talbot, K Krishnan, DF Covey, MR Wenk, M Craigon, Z Ruzsics, J Haas, A Angulo, WJ Griffiths, CK Glass, Y Wang, P Ghazal	Immunity	2012
Dual functions of Insig proteins in cholesterol homeostasis XY Dong, SQ Tang, JD Chen	Lipids in Health and Disease	2012
Lipid-lowering effects of tetradecylthioacetic acid in antipsychotic-exposed, female rats: challenges with long-term treatment S Skrede, J Fernø, B Bjørndal, WR Brede, P Bohov, RK Berge, VM Steen	PloS one	2012
Ovarian granulosa cells utilize scavenger receptor SR-BI to evade cellular cholesterol homeostatic control for steroid synthesis WA Lai, YT Yeh, MT Lee, LS Wu, FC Ke, JJ Hwang	Journal of lipid research	2012
Red clover extract exerts antidiabetic and hypolipidemic effects in db/db mice L Qiu, T Chen, F Zhong, Y Hong, L Chen, H Ye	Experimental and therapeutic medicine	2012
Omega-3 fatty acids for the treatment of non-alcoholic fatty liver disease MN di Minno, A Russolillo, R Lupoli, P Ambrosino, AD Minno, G Tarantino	World journal of gastroenterology : WJG	2012
Nordihydroguaiaretic acid improves metabolic dysregulation and aberrant hepatic lipid metabolism in mice by both PPARα-dependent and -independent pathways H Zhang, WJ Shen, Y Cortez, FB Kraemer, S Azhar	American journal of physiology. Gastrointestinal and liver physiology	2012
A novel 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) splice variant with an alternative exon 1 potentially encoding an extended N-terminus C Stormo, MK Kringen, RM Grimholt, JP Berg, AP Piehler	BMC Molecular Biology	2012
Regulation of the human prostacyclin receptor gene by the cholesterol-responsive SREBP1 EC Turner, BT Kinsella	Journal of lipid research	2012
Insulin stimulation of SREBP-1c processing in transgenic rat hepatocytes requires p70 S6-kinase JL Owen, Y Zhang, SH Bae, MS Farooqi, G Liang, RE Hammer, JL Goldstein, MS Brown	Proceedings of the National Academy of Sciences	2012
The plaque "micro" environment: microRNAs control the risk and the development of atherosclerosis KJ Rayner, KJ Moore	Current Atherosclerosis Reports	2012
Scientific side trips: six excursions from the beaten path MS Brown, JL Goldstein	The Journal of biological chemistry	2012
Dietary sea cucumber cerebroside alleviates orotic acid-induced excess hepatic adipopexis in rats B Zhang, C Xue, X Hu, J Xu, Z Li, J Wang, T Yanagita, Y Xue, Y Wang	Lipids in Health and Disease	2012
Blockade of cholesterol absorption by ezetimibe reveals a complex homeostatic network in enterocytes LJ Engelking, MR McFarlane, CK Li, G Liang	Journal of lipid research	2012
FoxO1 inhibits sterol regulatory element-binding protein-1c (SREBP-1c) gene expression via transcription factors Sp1 and SREBP-1c X Deng, W Zhang, IS O-Sullivan, JB Williams, Q Dong, EA Park, R Raghow, TG Unterman, MB Elam	The Journal of biological chemistry	2012
MicroRNAs regulating lipid metabolism in atherogenesis KJ Rayner, C Fernandez-Hernando, KJ Moore	Thrombosis and Haemostasis	2012
The Scap/SREBP Pathway Is Essential for Developing Diabetic Fatty Liver and Carbohydrate-Induced Hypertriglyceridemia in Animals YA Moon, G Liang, X Xie, M Frank-Kamenetsky, K Fitzgerald, V Koteliansky, MS Brown, JL Goldstein, JD Horton	Cell Metabolism	2012
Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci R Saxena, CC Elbers, Y Guo, I Peter, TR Gaunt, JL Mega, MB Lanktree, A Tare, BA Castillo, YR Li, T Johnson, M Bruinenberg, D Gilbert-Diamond, R Rajagopalan, BF Voight, A Balasubramanyam, J Barnard, F Bauer, J Baumert, T Bhangale, BO Böhm, PS Braund, PR Burton, HR Chandrupatla, R Clarke, RM Cooper-DeHoff, ED Crook, G Davey-Smith, IN Day, A de Boer, MC de Groot, F Drenos, J Ferguson, CS Fox, CE Furlong, Q Gibson, C Gieger, LA Gilhuijs-Pederson, JT Glessner, A Goel, Y Gong, SF Grant, DE Grobbee, C Hastie, SE Humphries, CE Kim, M Kivimaki, M Kleber, C Meisinger, M Kumari, TY Langaee, DA Lawlor, M Li, MT Lobmeyer, AH Maitland-van der Zee, MF Meijs, CM Molony, DA Morrow, G Murugesan, SK Musani, CP Nelson, SJ Newhouse, JR O'Connell, S Padmanabhan, J Palmen, SR Patel, CJ Pepine, M Pettinger, TS Price, S Rafelt, J Ranchalis, A Rasheed, E Rosenthal, I Ruczinski, S Shah, H Shen, G Silbernagel, EN Smith, AW Spijkerman, A Stanton, MW Steffes, B Thorand, M Trip, P van der Harst, DL van der A, EP van Iperen, J van Setten, JV van Vliet-Ostaptchouk, N Verweij, BH Wolffenbuttel, T Young, MH Zafarmand, JM Zmuda, M Boehnke, D Altshuler, M McCarthy, WH Kao, JS Pankow, TP Cappola, P Sever, N Poulter, M Caulfield, A Dominiczak, DC Shields, DL Bhatt, L Zhang, SP Curtis, J Danesh, JP Casas, YT van der Schouw, NC Onland-Moret, PA Doevendans, GW Dorn, M Farrall, GA FitzGerald, A Hamsten, R Hegele, AD Hingorani, MH Hofker, GS Huggins, T Illig, GP Jarvik, JA Johnson, OH Klungel, WC Knowler, W Koenig, W März, JB Meigs, O Melander, PB Munroe, BD Mitchell, SJ Bielinski, DJ Rader, MP Reilly, SS Rich, JI Rotter, D Saleheen, NJ Samani, EE Schadt, AR Shuldiner, R Silverstein, K Kottke-Marchant, PJ Talmud, H Watkins, FW Asselbergs, PI de Bakker, J McCaffery, C Wijmenga, MS Sabatine, JG Wilson, A Reiner, DW Bowden, H Hakonarson, DS Siscovick, BJ Keating	The American Journal of Human Genetics	2012
Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway WA Freed-Pastor, H Mizuno, X Zhao, A Langerød, SH Moon, R Rodriguez-Barrueco, A Barsotti, A Chicas, W Li, A Polotskaia, MJ Bissell, TF Osborne, B Tian, SW Lowe, JM Silva, AL Børresen-Dale, AJ Levine, J Bargonetti, C Prives	Cell	2012
Puerariae flos alleviates metabolic diseases in Western diet-loaded, spontaneously obese type 2 diabetic model mice K Kubo, T Shimada, R Onishi, M Tsubata, T Kamiya, R Nagamine, S Iizuka, Y Sai, S Amagaya, M Aburada, K Miyamoto	Journal of Natural Medicines	2012
Effects of atorvastatin metabolites on induction of drug-metabolizing enzymes and membrane transporters through human pregnane X receptor: Atorvastatin metabolites and PXR E Hoffart, L Ghebreghiorghis, AK Nussler, WE Thasler, TS Weiss, M Schwab, O Burk	British Journal of Pharmacology	2012
Endoplasmic reticulum factor ERLIN2 regulates cytosolic lipid content in cancer cells G Wang, X Zhang, JS Lee, X Wang, ZQ Yang, K Zhang	Biochemical Journal	2012
Combined effect of sesamin and α-lipoic acid on hepatic fatty acid metabolism in rats T Ide, A Azechi, S Kitade, Y Kunimatsu, N Suzuki, C Nakajima	European Journal of Nutrition	2012
Promoter analysis of the DHCR24 (3β-hydroxysterol Δ 24 -reductase) gene: characterization of SREBP (sterol-regulatoryelement-binding protein)-mediated activation LA Daimiel, ME Fernández‑Suárez, S Rodríguez‑Acebes, L Crespo, MA Lasunción, D Gómez‑Coronado, J Martínez‑Botas	Bioscience Reports	2012
Expression of R132H Mutational IDH1 in Human U87 Glioblastoma Cells Affects the SREBP1a Pathway and Induces Cellular Proliferation J Zhu, G Cui, M Chen, Q Xu, X Wang, D Zhou, S Lv, L Fu, Z Wang, J Zuo	Journal of Molecular Neuroscience	2012
Fluoxetine Induces Hepatic Lipid Accumulation Via Both Promotion of the SREBP1c-Related Lipogenesis and Reduction of Lipolysis in Primary Mouse Hepatocytes XM Feng, J Xiong, H Qin, W Liu, RN Chen, W Shang, R Ning, G Hu, J Yang	CNS Neuroscience & Therapeutics	2012
Deciphering the Transcriptional-Regulatory Network of Flocculation in Schizosaccharomyces pombe EJ Kwon, A Laderoute, K Chatfield-Reed, L Vachon, J Karagiannis, G Chua, A Kumar	PLoS genetics	2012
The A2b Adenosine Receptor Modulates Glucose Homeostasis and Obesity H Johnston-Cox, M Koupenova, D Yang, B Corkey, N Gokce, MG Farb, N LeBrasseur, K Ravid, HK Eltzschig	PloS one	2012
Cellular and Molecular Effect of MEHP Involving LXRα in Human Fetal Testis and Ovary V Muczynski, C Lecureuil, S Messiaen, MJ Guerquin, T NTumba-Byn, D Moison, W Hodroj, H Benjelloun, J Baijer, G Livera, R Frydman, A Benachi, R Habert, V Rouiller-Fabre, SR Singh	PloS one	2012
Adipocyte-Specific Protein Tyrosine Phosphatase 1B Deletion Increases Lipogenesis, Adipocyte Cell Size and Is a Minor Regulator of Glucose Homeostasis C Owen, A Czopek, A Agouni, L Grant, R Judson, EK Lees, GD Mcilroy, O Göransson, A Welch, KK Bence, BB Kahn, BG Neel, N Mody, M Delibegović, ME Saez	PloS one	2012
Lipoproteins in Drosophila melanogaster—Assembly, Function, and Influence on Tissue Lipid Composition W Palm, JL Sampaio, M Brankatschk, M Carvalho, A Mahmoud, A Shevchenko, S Eaton, RP Kühnlein	PLoS genetics	2012
Spatial Distribution of the Pathways of Cholesterol Homeostasis in Human Retina W Zheng, RE Reem, S Omarova, S Huang, PL DiPatre, CD Charvet, CA Curcio, IA Pikuleva, E Chaum	PloS one	2012
Consequences of Exchanging Carbohydrates for Proteins in the Cholesterol Metabolism of Mice Fed a High-fat Diet F Raymond, L Wang, M Moser, S Metairon, R Mansourian, MC Zwahlen, M Kussmann, A Fuerholz, K Macé, CJ Chou, S Blanc	PloS one	2012
Inhibition of Intestinal Bile Acid Transporter Slc10a2 Improves Triglyceride Metabolism and Normalizes Elevated Plasma Glucose Levels in Mice T Lundåsen, EM Andersson, M Snaith, H Lindmark, J Lundberg, AM Östlund-Lindqvist, B Angelin, M Rudling, M Pietropaolo	PloS one	2012
Omega-3 fatty acid supplementation and cardiovascular disease: Thematic Review Series: New Lipid and Lipoprotein Targets for the Treatment of Cardiometabolic Diseases DB Jump, CM Depner, S Tripathy	Journal of lipid research	2012
NOX4 Pathway as a Source of Selective Insulin Resistance and Responsiveness X Wu, KJ Williams	Arteriosclerosis, thrombosis, and vascular biology	2012
Novel metabolites and roles for α-tocopherol in humans and mice discovered by mass spectrometry–based metabolomics1–5 CH Johnson, O Slanař, KW Krausz, DW Kang, AD Patterson, JH Kim, H Luecke, FJ Gonzalez, JR Idle	The American journal of clinical nutrition	2012
The Oxysterol 24 (S) ,25‐Epoxycholesterol Attenuates Human Smooth Muscle–Derived Foam Cell Formation Via Reduced Low‐Density Lipoprotein Uptake and Enhanced Cholesterol Efflux MM Beyea, S Reaume, CG Sawyez, JY Edwards, C O'Neil, RA Hegele, JG Pickering, MW Huff	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease	2012
5-Cholesten-3β,25-Diol 3-Sulfate Decreases Lipid Accumulation in Diet-Induced Nonalcoholic Fatty Liver Disease Mouse Model L Xu, JK Kim, Q Bai, X Zhang, G Kakiyama, H Min, AJ Sanyal, WM Pandak, S Ren	Molecular pharmacology	2012
SREBP-1 und Fettleber: Klinische Bedeutung für Diabetes, Adipositas, Dyslipidämie und Atherosklerose D Müller-Wieland, B Knebel, J Haas, J Kotzka	Herz	2012
β-Amyloid Inhibits Protein Prenylation and Induces Cholesterol Sequestration by Impairing SREBP-2 Cleavage Mohamed A, Saavedra L, Di Pardo A, Sipione S, Posse de Chaves E	Journal of Neuroscience	2012
Carbon Source Metabolism and Its Regulation in Cancer Cells Yin C, Qie S, Sang N	Critical reviews in eukaryotic gene expression	2012
Next generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy Joyce M. Slingerland, Seth A. Wander, Bryan Hennessy	Journal of Clinical Investigation	2011
An LXR Agonist Promotes Glioblastoma Cell Death through Inhibition of an EGFR/AKT/SREBP-1/LDLR-Dependent Pathway D Guo, F Reinitz, M Youssef, C Hong, D Nathanson, D Akhavan, D Kuga, AN Amzajerdi, H Soto, S Zhu, I Babic, K Tanaka, J Dang, A Iwanami, B Gini, J DeJesus, DD Lisiero, TT Huang, RM Prins, PY Wen, HI Robins, MD Prados, LM DeAngelis, IK Mellinghoff, MP Mehta, CD James, A Chakravarti, TF Cloughesy, P Tontonoz, PS Mischel	Cancer Discovery	2011
Comprehensive Physiology R Terjung	Comprehensive Physiology	2011
Hepatic ABCA1 and VLDL triglyceride production M Liu, S Chung, GS Shelness, JS Parks	Biochimica et Biophysica Acta	2011
New insights into the mechanism of low high-density lipoprotein cholesterol in obesity H Wang, DQ Peng	Lipids in Health and Disease	2011
Postprandial Hepatic Lipid Metabolism Requires Signaling through Akt2 Independent of the Transcription Factors FoxA2, FoxO1, and SREBP1c M Wan, KF Leavens, D Saleh, RM Easton, DA Guertin, TR Peterson, KH Kaestner, DM Sabatini, MJ Birnbaum	Cell Metabolism	2011
Inhibition of Notch signaling ameliorates insulin resistance in a FoxO1–dependent manner UB Pajvani, CJ Shawber, VT Samuel, AL Birkenfeld, GI Shulman, J Kitajewski, D Accili	Nature Medicine	2011
AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-induced Insulin Resistant Mice Y Li, S Xu, MM Mihaylova, B Zheng, X Hou, B Jiang, O Park, Z Luo, E Lefai, JY Shyy, B Gao, M Wierzbicki, TJ Verbeuren, RJ Shaw, RA Cohen, M Zang	Cell Metabolism	2011
MicroRNAs in metabolism and metabolic diseases V Rottiers, SH Najafi-Shoushtari, F Kristo, S Gurumurthy, L Zhong, Y Li, DE Cohen, RE Gerszten, N Bardeesy, R Mostoslavsky, AM Näär	Cold Spring Harbor Symposia on Quantitative Biology	2011
Impact of oxLDL on Cholesterol-Rich Membrane Rafts I Levitan, TP Shentu	Journal of Lipids	2011
Vitamin D receptor agonist doxercalciferol modulates dietary fat-induced renal disease and renal lipid metabolism XX Wang, T Jiang, Y Shen, H Santamaria, N Solis, C Arbeeny, M Levi	AJP Renal Physiology	2011
Bariatric Surgery and Renal Function A Currie, A Chetwood, AR Ahmed	Obesity Surgery	2011
Niemann-Pick C1-Like 1 (NPC1L1) Protein in Intestinal and Hepatic Cholesterol Transport L Jia, JL Betters, L Yu	Annual Review of Physiology	2011
Studies of gene variants related to inflammation, oxidative stress, dyslipidemia, and obesity: implications for a nutrigenetic approach ML Curti, P Jacob, MC Borges, MM Rogero, SR Ferreira	Journal of Obesity	2011
Inhibitory effect of schisandrin B on free fatty acid-induced steatosis in L-02 cells JH Chu, H Wang, Y Ye, PK Chan, SY Pan, WF Fong, ZL Yu	World journal of gastroenterology : WJG	2011
Citrus flavonoids repress the mRNA for stearoyl-CoA desaturase, a key enzyme in lipid synthesis and obesity control, in rat primary hepatocytes LA Nichols, DE Jackson, JA Manthey, SD Shukla, LJ Holland	Lipids in Health and Disease	2011
Polyomic profiling reveals significant hepatic metabolic alterations in glucagon-receptor (GCGR) knockout mice: implications on anti-glucagon therapies for diabetes J Yang, ML MacDougall, MT McDowell, L Xi, R Wei, WJ Zavadoski, MP Molloy, JD Baker, M Kuhn, O Cabrera, JL Treadway	BMC Genomics	2011
MicroRNAs in lipid metabolism C Fernández-Hernando, Y Suárez, KJ Rayner, KJ Moore	Current Opinion in Lipidology	2011
mTOR Complex 1 Regulates Lipin 1 Localization to Control the SREBP Pathway TR Peterson, SS Sengupta, TE Harris, AE Carmack, SA Kang, E Balderas, DA Guertin, KL Madden, AE Carpenter, BN Finck, DM Sabatini	Cell	2011
Side-chain oxysterols: From cells to membranes to molecules BN Olsen, PH Schlesinger, DS Ory, NA Baker	Biochimica et Biophysica Acta (BBA) - Biomembranes	2011
Regulation of Lipid Homeostasis by the Bifunctional SREBF2-miR33a Locus GT Bommer, OA MacDougald	Cell Metabolism	2011
Akt Stimulates Hepatic SREBP1c and Lipogenesis through Parallel mTORC1-Dependent and Independent Pathways JL Yecies, HH Zhang, S Menon, S Liu, D Yecies, AI Lipovsky, C Gorgun, DJ Kwiatkowski, GS Hotamisligil, CH Lee, BD Manning	Cell Metabolism	2011
Uncoupling hypoxia signaling from oxygen sensing in the liver results in hypoketotic hypoglycemic death B Kucejova, NE Sunny, AD Nguyen, R Hallac, X Fu, S Peña-Llopis, RP Mason, RJ Deberardinis, XJ Xie, R Debose-Boyd, VD Kodibagkar, SC Burgess, J Brugarolas	Oncogene	2011
The transcription factor cyclic AMP–responsive element–binding protein H regulates triglyceride metabolism JH Lee, P Giannikopoulos, SA Duncan, J Wang, CT Johansen, JD Brown, J Plutzky, RA Hegele, LH Glimcher, AH Lee	Nature Medicine	2011
The Role of MicroRNAs in Cholesterol Efflux and Hepatic Lipid Metabolism KJ Moore, KJ Rayner, Y Suárez, C Fernández-Hernando	Annual Review of Nutrition	2011
Regulation of cholesterol homeostasis L Goedeke, C Fernández-Hernando	Cellular and Molecular Life Sciences	2011
Changes in cholesterol homeostasis modify the response of F1B hamsters to dietary very long chain n-3 and n-6 polyunsaturated fatty acids JL Lecker, NR Matthan, JT Billheimer, DJ Rader, AH Lichtenstein	Lipids in Health and Disease	2011
SREBPs: metabolic integrators in physiology and metabolism TI Jeon, TF Osborne	Trends in Endocrinology and Metabolism	2011
Increased Very Low Density Lipoprotein Secretion, Hepatic Steatosis, and Insulin Resistance SH Choi, HN Ginsberg	Trends in endocrinology and metabolism: TEM	2011
Pathophysiology of insulin resistance and steatosis in patients with chronic viral hepatitis M Basaranoglu, G Basaranoglu	World journal of gastroenterology : WJG	2011
Human Fatty Liver Disease: Old Questions and New Insights JC Cohen, JD Horton, HH Hobbs	Science (New York, N.Y.)	2011
THE CONTRIBUTION OF ER STRESS TO LIVER DISEASES L Dara, C Ji, N Kaplowitz	Hepatology	2011
Inhibition of miR-33a/b in non-human primates raises plasma HDL and reduces VLDL triglycerides KJ Rayner, CC Esau, FN Hussain, AL McDaniel, SM Marshall, JM van Gils, TD Ray, FJ Sheedy, L Goedeke, X Liu, OG Khatsenko, V Kaimal, CJ Lees, C Fernandez-Hernando, EA Fisher, RE Temel, KJ Moore	Nature	2011
Early Growth Response 1 (Egr1) Regulates Cholesterol Biosynthetic Gene Expression* NG Gokey, C Lopez-Anido, AL Gillian-Daniel, J Svaren	The Journal of biological chemistry	2011
Genome-wide Localization of SREBP-2 in Hepatic Chromatin Predicts a Role in Autophagy YK Seo, TI Jeon, HK Chong, J Biesinger, X Xie, TF Osborne	Cell Metabolism	2011
Atf6 plays protective and pathologic roles in fatty liver disease due to endoplasmic reticulum stress A Cinaroglu, C Gao, D Imrie, KC Sadler	Hepatology	2011
p38 Mitogen-Activated Protein Kinase and Liver X Receptor-α Mediate the Leptin Effect on Sterol Regulatory Element Binding Protein-1c Expression in Hepatic Stellate Cells K Yan, X Deng, X Zhai, M Zhou, X Jia, L Luo, M Niu, H Zhu, H Qiang, Y Zhou	Molecular Medicine	2011
Effects of antisense-mediated inhibition of 11β-hydroxysteroid dehydrogenase type 1 on hepatic lipid metabolism[S] G Li, A Hernandez-Ono, RM Crooke, MJ Graham, HN Ginsberg	Journal of lipid research	2011
A novel potent synthetic steroidal liver X receptor agonist lowers plasma cholesterol and triglycerides and reduces atherosclerosis in LDLR–/– mice D Peng, RA Hiipakka, JT Xie, Q Dai, JM Kokontis, CA Reardon, GS Getz, S Liao	British Journal of Pharmacology	2011
Differential Roles of Hyperglycemia and Hypoinsulinemia in Diabetes Induced Retinal Cell Death: Evidence for Retinal Insulin Resistance PE Fort, MK Losiewicz, CE Reiter, RS Singh, M Nakamura, SF Abcouwer, AJ Barber, TW Gardner	PloS one	2011
Mineralocorticoid hypertension V Gupta	Indian journal of endocrinology and metabolism	2011
A spontaneous mutation in Srebf2 leads to cataracts and persistent skin wounds in the lens opacity 13 (lop13) mouse KM Merath, B Chang, R Dubielzig, R Jeannotte, DJ Sidjanin	Mammalian genome : official journal of the International Mammalian Genome Society	2011
Liraglutide Prevents Hypoadiponectinemia-Induced Insulin Resistance and Alterations of Gene Expression Involved in Glucose and Lipid Metabolism L Li, Z Miao, R Liu, M Yang, H Liu, G Yang	Molecular Medicine	2011
PGC1α contributes to dysmyelination in experimental models of Huntington's disease Z Xiang, M Valenza, L Cui, V Leoni, HK Jeong, E Brilli, J Zhang, Q Peng, W Duan, SA Reeves, E Cattaneo, D Krainc	The Journal of neuroscience : the official journal of the Society for Neuroscience	2011
miR-33a/b contribute to the regulation of fatty acid metabolism and insulin signaling A Dávalos, L Goedeke, P Smibert, CM Ramírez, NP Warrier, U Andreo, D Cirera-Salinas, K Rayner, U Suresh, JC Pastor-Pareja, E Esplugues, EA Fisher, LO Penalva, KJ Moore, Y Suárez, EC Lai, C Fernández-Hernando	Proceedings of the National Academy of Sciences	2011
Linking Lipid Metabolism to the Innate Immune Response in Macrophages through Sterol Regulatory Element Binding Protein -1a SS Im, L Yousef, C Blaschitz, JZ Liu, RA Edwards, SG Young, M Raffatellu, TF Osborne	Cell Metabolism	2011
25-Hydroxycholesterol Increases the Availability of Cholesterol in Phospholipid Membranes BN Olsen, PH Schlesinger, DS Ory, NA Baker	Biophysical Journal	2011
Lipocalin 13 protein protects against hepatic steatosis by both inhibiting lipogenesis and stimulating fatty acid β-oxidation L Sheng, KW Cho, Y Zhou, H Shen, L Rui	The Journal of biological chemistry	2011
PGC1α promotes tumor growth by inducing gene expression programs supporting lipogenesis K Bhalla, BJ Hwang, RE Dewi, L Ou, W Twaddel, HB Fang, SB Vafai, F Vazquez, P Puigserver, L Boros, GD Girnun	Cancer research	2011
Nobiletin Attenuates VLDL Overproduction, Dyslipidemia, and Atherosclerosis in Mice With Diet-Induced Insulin Resistance EE Mulvihill, JM Assini, JK Lee, EM Allister, BG Sutherland, JB Koppes, CG Sawyez, JY Edwards, DE Telford, A Charbonneau, P St-Pierre, A Marette, MW Huff	Diabetes	2011
Other ways to skin a cat: Activating SREBP without Scap C Ozdemir, RB Rawson	Fly	2011
Sulfation of 25-hydroxycholesterol by SULT2B1b decreases cellular lipids via the LXR/SREBP-1c signaling pathway in human aortic endothelial cells Q Bai, L Xu, G Kakiyama, MA Runge-Morris, PB Hylemon, L Yin, WM Pandak, S Ren	Atherosclerosis	2011
Pleiotropic Effects of a Schweinfurthin on Isoprenoid Homeostasis SA Holstein, CH Kuder, H Tong, RJ Hohl	Lipids	2011
Glycerolipid and cholesterol ester analyses in biological samples by mass spectrometry RC Murphy, TJ Leiker, RM Barkley	Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids	2011
A Conserved SREBP-1/Phosphatidylcholine Feedback Circuit Regulates Lipogenesis in Metazoans AK Walker, RL Jacobs, JL Watts, V Rottiers, K Jiang, DM Finnegan, T Shioda, M Hansen, F Yang, LJ Niebergall, DE Vance, M Tzoneva, AC Hart, AM Näär	Cell	2011
Identification of high-copper-responsive target pathways in Atp7b knockout mouse liver by GSEA on microarray data sets K He, Z Chen, Y Ma, Y Pan	Mammalian Genome	2011
Self-assembling enzymes and the origins of the cytoskeleton RM Barry, Z Gitai	Current Opinion in Microbiology	2011
Transcription coactivator mediator subunit MED1 Is required for the development of fatty liver in the mouse L Bai, Y Jia, N Viswakarma, J Huang, A Vluggens, NE Wolins, N Jafari, MS Rao, J Borensztajn, G Yang, JK Reddy	Hepatology	2011
Effects of hypolipidemic agent nordihydroguaiaretic acid on lipid droplets and hepatitis C virus GH Syed, A Siddiqui	Hepatology	2011
OSBP-Related Protein 8 (ORP8) Regulates Plasma and Liver Tissue Lipid Levels and Interacts with the Nucleoporin Nup62 T Zhou, S Li, W Zhong, T Vihervaara, O Béaslas, J Perttilä, W Luo, Y Jiang, M Lehto, VM Olkkonen, D Yan, J Gruenberg	PloS one	2011
Insulin-Regulated Srebp-1c and Pck1 mRNA Expression in Primary Hepatocytes from Zucker Fatty but Not Lean Rats Is Affected by Feeding Conditions Y Zhang, W Chen, R Li, Y Li, Y Ge, G Chen, NS Wong	PloS one	2011
Hepatic Deletion of Smad7 in Mouse Leads to Spontaneous Liver Dysfunction and Aggravates Alcoholic Liver Injury L Zhu, L Wang, X Wang, X Luo, L Yang, R Zhang, H Yin, D Xie, Y Pan, Y Chen, B Sun	PloS one	2011
Dietary Cholesterol Reduces Plasma Triacylglycerol in Apolipoprotein E-Null Mice: Suppression of Lipin-1 and -2 in the Glycerol-3-Phosphate Pathway T Obama, S Nagaoka, K Akagi, R Kato, N Horiuchi, Y Horai, T Aiuchi, S Arata, T Yamaguchi, M Watanabe, H Itabe, JM Lobaccaro	PloS one	2011
Identification of Luminal Loop 1 of Scap Protein as the Sterol Sensor That Maintains Cholesterol Homeostasis M Motamed, Y Zhang, ML Wang, J Seemann, HJ Kwon, JL Goldstein, MS Brown	The Journal of biological chemistry	2011
Early steps in steroidogenesis: intracellular cholesterol trafficking: Thematic Review Series: Genetics of Human Lipid Diseases WL Miller, HS Bose	Journal of lipid research	2011
The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders WL Miller, RJ Auchus	Endocrine reviews	2011
Effects of Adiposity on Plasma Lipid Response to Reductions in Dietary Saturated Fatty Acids and Cholesterol MR Flock, MH Green, PM Kris-Etherton	Advances in nutrition (Bethesda, Md.)	2011
MicroRNA Modulation of Cholesterol Homeostasis C Fernández-Hernando, KJ Moore, WC Sessa	Arteriosclerosis, thrombosis, and vascular biology	2011
Antisense oligonucleotide reduction of apoB-ameliorated atherosclerosis in LDL receptor-deficient mice AE Mullick, W Fu, MJ Graham, RG Lee, D Witchell, TA Bell, CP Whipple, RM Crooke	Journal of lipid research	2011
Gonadotropin-regulated Testicular RNA Helicase (GRTH/DDX25), a Negative Regulator of Luteinizing/Chorionic Gonadotropin Hormone-induced Steroidogenesis in Leydig Cells M Fukushima, J Villar, CH Tsai-Morris, ML Dufau	The Journal of biological chemistry	2011
Human SREBP1c Expression in Liver Is Directly Regulated by Peroxisome Proliferator-activated Receptor α (PPARα) A Fernández-Alvarez, MS Alvarez, R Gonzalez, C Cucarella, J Muntané, M Casado	The Journal of biological chemistry	2011
Berberine regulated Gck, G6pc, Pck1 and Srebp-1c expression and activated AMP-activated protein kinase in primary rat hepatocytes. Ge Y, Zhang Y, Li R, Chen W, Li Y, Chen G	International journal of biological sciences	2011
Mechanism of AMPK suppression of LXR-dependent Srebp-1c transcription. Yap F, Craddock L, Yang J	International journal of biological sciences	2011
Id3 is a novel atheroprotective factor containing a functionally significant single-nucleotide polymorphism associated with intima-media thickness in humans AC Doran, AB Lehtinen, N Meller, MJ Lipinski, RP Slayton, SN Oldham, MD Skaflen, J Yeboah, SS Rich, DW Bowden, CA McNamara	Circulation research	2010
A systems approach to mapping transcriptional networks controlling surfactant homeostasis Y Xu, M Zhang, Y Wang, P Kadambi, V Dave, LJ Lu, JA Whitsett	BMC Genomics	2010
The Role of Muscle Insulin Resistance in the Pathogenesis of Atherogenic Dyslipidemia and Nonalcoholic Fatty Liver Disease Associated with the Metabolic Syndrome FR Jornayvaz, VT Samuel, GI Shulman	Annual Review of Nutrition	2010
Cholesterol Binding and Cholesterol Transport Proteins: JR Harris		2010
Insulin- and leptin-regulated fatty acid uptake plays a key causal role in hepatic steatosis in mice with intact leptin signaling but not in ob/ob or db/db mice F Ge, S Zhou, C Hu, HL 4th, PD Berk	AJP Gastrointestinal and Liver Physiology	2010
Tgif1 represses apolipoprotein gene expression in liver TA Melhuish, DD Chung, GA Bjerke, D Wotton	Journal of Cellular Biochemistry	2010
Altered Glucose Homeostasis in Mice with Liver-specific Deletion of Src Homology Phosphatase 2* K Matsuo, M Delibegovic, I Matsuo, N Nagata, S Liu, A Bettaieb, Y Xi, K Araki, W Yang, BB Kahn, BG Neel, FG Haj	The Journal of biological chemistry	2010
Impaired adipogenic response to thiazolidinediones in mice expressing human apolipoproteinE4 JM Arbones-Mainar, LA Johnson, MK Altenburg, HS Kim, N Maeda	The FASEB Journal	2010
Expression of miR-33 from an SREBP2 Intron Inhibits Cholesterol Export and Fatty Acid Oxidation* I Gerin, LA Clerbaux, O Haumont, N Lanthier, AK Das, CF Burant, IA Leclercq, OA MacDougald, GT Bommer	The Journal of biological chemistry	2010
Cdc2-like kinase 2 is an insulin-regulated suppressor of hepatic gluconeogenesis JT Rodgers, W Haas, SP Gygi, P Puigserver	Cell Metabolism	2010
Genetic control ofde novolipogenesis: role in diet-induced obesity MS Strable, JM Ntambi	Critical Reviews in Biochemistry and Molecular Biology	2010
MiR-33 contributes to the regulation of cholesterol homeostasis KJ Rayner, Y Suárez, A Dávalos, S Parathath, ML Fitzgerald, N Tamehiro, EA Fisher, KJ Moore, C Fernández-Hernando	Science (New York, N.Y.)	2010
Deciphering the nuclear bile acid receptor FXR paradigm S Modica, RM Gadaleta, A Moschetta	Nuclear receptor signaling	2010
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 2 Controls Energy Balance and Peripheral Insulin Action in Mice G Heinrich, S Ghosh, AM Deangelis, JM Schroeder-Gloeckler, PR Patel, TR Castaneda, S Jeffers, AD Lee, DY Jung, Z Zhang, DM Opland, MG Myers, JK Kim, SM Najjar	Gastroenterology	2010
Inhibition of obesity-induced hepatic ER stress by early insulin therapy in obese diabetic rats W Sun, Y Bi, H Liang, M Cai, X Chen, Y Zhu, M Li, F Xu, Q Yu, X He, J Ye, J Weng	Endocrine	2010
Dysregulation of sterol regulatory element binding protein–1c in livers of morbidly obese women is associated with altered suppressor of cytokine signaling–3 and signal transducer and activator of transcription–1 signaling MB Elam, C Yellaturu, GE Howell, X Deng, GS Cowan, P Kumar, EA Park, ML Hiler, HG Wilcox, TA Hughes, GA Cook, R Raghow	Metabolism	2010
Phytosterols and phytosterolemia: gene–diet interactions MC Izar, DM Tegani, SH Kasmas, FA Fonseca	Genes & Nutrition	2010
Induced polymerization of mammalian acetyl-CoA carboxylase by MIG12 provides a tertiary level of regulation of fatty acid synthesis CW Kim, YA Moon, SW Park, D Cheng, HJ Kwon, JD Horton	Proceedings of the National Academy of Sciences	2010
Identification by whole-genome resequencing of gene defect responsible for severe hypercholesterolemia J Rios, E Stein, J Shendure, HH Hobbs, JC Cohen	Human Molecular Genetics	2010
Diabetes and Insulin in Regulation of Brain Cholesterol Metabolism R Suzuki, K Lee, E Jing, SB Biddinger, JG McDonald, TJ Montine, S Craft, CR Kahn	Cell Metabolism	2010
Differential expression and function of ABCG1 and ABCG4 during development and aging DD Bojanic, PT Tarr, GD Gale, DJ Smith, D Bok, B Chen, S Nusinowitz, A Lövgren-Sandblom, I Björkhem, PA Edwards	Journal of lipid research	2010
Adipose tissue branched chain amino acid (BCAA) metabolism modulates circulating BCAA levels MA Herman, P She, OD Peroni, CJ Lynch, BB Kahn	The Journal of biological chemistry	2010
Control of cholesterol synthesis through regulated ER-associated degradation of HMG CoA reductase Y Jo, RA Debose-Boyd	Critical Reviews in Biochemistry and Molecular Biology	2010
Hair growth defects in Insig-deficient mice caused by cholesterol precursor accumulation and reversed by simvastatin BM Evers, MS Farooqi, JM Shelton, JA Richardson, JL Goldstein, MS Brown, G Liang	Journal of Investigative Dermatology	2010
Regulation of hepatic gene expression by saturated fatty acids T Vallim, AM Salter	Prostaglandins, leukotrienes, and essential fatty acids	2010
A feed-forward loop amplifies nutritional regulation of PNPLA3 Y Huang, S He, JZ Li, YK Seo, TF Osborne, JC Cohen, HH Hobbs	Proceedings of the National Academy of Sciences	2010
Medicine. HDL miR-ed down by SREBP introns MS Brown, J Ye, JL Goldstein	Science (New York, N.Y.)	2010
24S-hydroxycholesterol effects on lipid metabolism genes are modeled in traumatic brain injury CM Cartagena, MP Burns, GW Rebeck	Brain Research	2010
alpha(1)-fetoprotein transcription factor (FTF)/liver receptor homolog-1 (LRH-1) is an essential lipogenic regulator Z Xu, L Ouyang, AD Castillo-Olivares, WM Pandak, G Gil	Biochimica et Biophysica Acta	2010
Age-Related Hypercholesterolemia and HMG-CoA Reductase Dysregulation: Sex Does Matter (A Gender Perspective) L Trapani, V Pallottini	Current Gerontology and Geriatrics Research	2010
Coordinate Transcriptomic and Metabolomic Effects of the Insulin Sensitizer Rosiglitazone on Fundamental Metabolic Pathways in Liver, Soleus Muscle, and Adipose Tissue in Diabetic db/db Mice SL Bouter, M Rodriguez, N Guigal-Stephan, S Courtade-Gaïani, L Xuereb, C Montrion, V Croixmarie, T Umbdenstock, C Boursier-Neyret, M Lonchampt, M Brun, C Dacquet, A Ktorza, BP Lockhart, JP Galizzi	PPAR Research	2010
Insulin signaling in fatty acid and fat synthesis: a transcriptional perspective RH Wong, HS Sul	Current Opinion in Pharmacology	2010
Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis S Li, MS Brown, JL Goldstein	Proceedings of the National Academy of Sciences	2010
Intracellular delivery strategies for microRNAs and potential therapies for human cardiovascular diseases MA Shi, GP Shi	Science signaling	2010
Unacylated ghrelin rapidly modulates lipogenic and insulin signaling pathway gene expression in metabolically active tissues of GHSR deleted mice PJ Delhanty, Y Sun, JA Visser, A Kerkwijk, M Huisman, WF van Ijcken, S Swagemakers, RG Smith, AP Themmen, AJ der Lely	PloS one	2010
Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP AK Walker, F Yang, K Jiang, JY Ji, JL Watts, A Purushotham, O Boss, ML Hirsch, S Ribich, JJ Smith, K Israelian, CH Westphal, JT Rodgers, T Shioda, SL Elson, P Mulligan, H Najafi-Shoushtari, JC Black, JK Thakur, LC Kadyk, JR Whetstine, R Mostoslavsky, P Puigserver, X Li, NJ Dyson, AC Hart, AM Näär	Genes & development	2010
Chemical combinations elucidate pathway interactions and regulation relevant to Hepatitis C replication CM Owens, C Mawhinney, JM Grenier, R Altmeyer, MS Lee, AA Borisy, J Lehár, LM Johansen	Molecular Systems Biology	2010
Nutrigenomics therapy of hepatisis C virus induced-hepatosteatosis Q Liu, S Bengmark, S Qu	BMC Gastroenterology	2010
Glutathione deficiency down-regulates hepatic lipogenesis in rats C Brandsch, T Schmidt, D Behn, K Weisse, AS Mueller, GI Stangl	Lipids in Health and Disease	2010
Insulin sensitivity regulates cholesterol metabolism to a greater extent than obesity: lessons from the METSIM Study H Gylling, M Hallikainen, J Pihlajamäki, P Simonen, J Kuusisto, M Laakso, TA Miettinen	Journal of lipid research	2010
Induction of fatty acid synthesis is a key requirement for phagocytic differentiation of human monocytes J Ecker, G Liebisch, M Englmaier, M Grandl, H Robenek, G Schmitz	Proceedings of the National Academy of Sciences	2010
Quantitative proteomics analysis of inborn errors of cholesterol synthesis: identification of altered metabolic pathways in DHCR7 and SC5D deficiency XS Jiang, PS Backlund, CA Wassif, AL Yergey, FD Porter	Molecular & cellular proteomics : MCP	2010
Characterization of the human insulin-induced gene 2 (INSIG2) promoter: the role of Ets-binding motifs A Fernández-Alvarez, MS Alvarez, C Cucarella, M Casado	The Journal of biological chemistry	2010
Chronic social defeat stress disrupts regulation of lipid synthesis JC Chuang, H Cui, BL Mason, M Mahgoub, AL Bookout, HG Yu, M Perello, JK Elmquist, JJ Repa, JM Zigman, M Lutter	Journal of lipid research	2010
INSIG1 influences obesity-related hypertriglyceridemia in humans EM Smith, Y Zhang, TM Baye, S Gawrieh, R Cole, J Blangero, MA Carless, JE Curran, TD Dyer, LJ Abraham, EK Moses, AH Kissebah, LJ Martin, M Olivier	Journal of lipid research	2010
Intramembrane glycine mediates multimerization of Insig-2, a requirement for sterol regulation in Chinese hamster ovary cells PC Lee, RA DeBose-Boyd	Journal of lipid research	2010
ABCD2 is abundant in adipose tissue and opposes the accumulation of dietary erucic acid (C22:1) in fat J Liu, NS Sabeva, S Bhatnagar, XA Li, A Pujol, GA Graf	Journal of lipid research	2010
Ginkgo biloba extract enhances glucose tolerance in hyperinsulinism-induced hepatic cells L Zhou, Q Meng, T Qian, Z Yang	Journal of Natural Medicines	2010
A large indel mutation of the bovine ADD1/SREBP1c gene and its effects on growth traits in some native cattle breeds from China YZ Huang, EP Zhang, J Wang, YT Huai, L Ma, FY Chen, XY Lan, CZ Lei, XT Fang, JQ Wang, H Chen	Molecular Biology Reports	2010
Adipose triacylglycerol lipase is a major regulator of hepatic lipid metabolism but not insulin sensitivity in mice SM Turpin, AJ Hoy, RD Brown, CG Rudaz, J Honeyman, M Matzaris, MJ Watt	Diabetologia	2010
MicroRNA-33 and the SREBP Host Genes Cooperate to Control Cholesterol Homeostasis SH Najafi-Shoushtari, F Kristo, Y Li, T Shioda, DE Cohen, RE Gerszten, AM Naar	Science	2010
Niemann-Pick C1-Like 1 deletion in mice prevents high-fat diet-induced fatty liver by reducing lipogenesis[S] L Jia, Y Ma, S Rong, JL Betters, P Xie, S Chung, N Wang, W Tang, L Yu	Journal of lipid research	2010
Hepatic FoxO1 Ablation Exacerbates Lipid Abnormalities during Hyperglycemia* RA Haeusler, S Han, D Accili	The Journal of biological chemistry	2010
Sterol regulatory element binding protein and dietary lipid regulation of fatty acid synthesis in the mammary epithelium MC Rudolph, J Monks, V Burns, M Phistry, R Marians, MR Foote, DE Bauman, SM Anderson, MC Neville	American journal of physiology. Endocrinology and metabolism	2010
Multi-tissue, selective PPARγ modulation of insulin sensitivity and metabolic pathways in obese rats G Hsiao, J Chapman, JM Ofrecio, J Wilkes, JL Resnik, D Thapar, S Subramaniam, DD Sears	American journal of physiology. Endocrinology and metabolism	2010
New insights into S2P signaling cascades: Regulation, variation, and conservation G Chen, X Zhang	Protein science : a publication of the Protein Society	2010
Accessibility of Cholesterol in Endoplasmic Reticulum Membranes and Activation of SREBP-2 Switch Abruptly at a Common Cholesterol Threshold A Sokolov, A Radhakrishnan	The Journal of biological chemistry	2010
Sterol Regulatory Element-binding Protein (SREBP)-1-mediated Lipogenesis Is Involved in Cell Senescence* YM Kim, HT Shin, YH Seo, HO Byun, SH Yoon, IK Lee, DH Hyun, HY Chung, G Yoon	The Journal of biological chemistry	2010
Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma DF Calvisi, C Wang, C Ho, S Ladu, SA Lee, S Mattu, G Destefanis, S Delogu, A Zimmermann, J Ericsson, S Brozzetti, T Staniscia, X Chen, F Dombrowski, M Evert	Gastroenterology	2010
Effect of bezafibrate on hepatic oxidative stress: comparison between conventional experimental doses and clinically-relevant doses in mice T Nakajima, N Tanaka, G Li, R Hu, Y Kamijo, A Hara, T Aoyama	Redox report : communications in free radical research	2010
Pathogenesis of alcoholic liver disease: the role of nuclear receptors MA Gyamfi, YJ Wan	Experimental biology and medicine (Maywood, N.J.)	2010
SREBP isoform and SREBP target gene expression during rat primary hepatocyte culture J Wu, AJ Dickson	In vitro cellular & developmental biology. Animal	2010
Effect of Ezetimibe on Hepatic Fat, Inflammatory Markers, and Apolipoprotein B-100 Kinetics in Insulin-Resistant Obese Subjects on a Weight Loss Diet DC Chan, GF Watts, SK Gan, EM Ooi, PH Barrett	Diabetes care	2010
Desalinated underground seawater of Jeju Island (Korea) improves lipid metabolism in mice fed diets containing high fat and increases antioxidant potential in t-BHP treated HepG2 cells JR Noh, GT Gang, YH Kim, KJ Yang, CH Lee, OS Na, GJ Kim, WK Oh, YD Lee	Nutrition Research and Practice	2010
Regulatory role for phosphatidylcholine transfer protein/StarD2 in the metabolic response to peroxisome proliferator activated receptor alpha (PPARα) HW Kang, K Kanno, EF Scapa, DE Cohen	Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids	2010
Hepatitis C virus hijacks host lipid metabolism GH Syed, Y Amako, A Siddiqui	Trends in Endocrinology & Metabolism	2010
The potential of cytokines as safety biomarkers for drug-induced liver injury HG Laverty, DJ Antoine, C Benson, M Chaponda, D Williams, BK Park	European Journal of Clinical Pharmacology	2010
Sustained upregulation of stearoyl-CoA desaturase in bovine mammary tissue with contrasting changes in milk fat synthesis and lipogenic gene networks caused by lipid supplements G Invernizzi, BJ Thering, MA McGuire, G Savoini, JJ Loor	Functional & Integrative Genomics	2010
microRNAs and cholesterol metabolism KJ Moore, KJ Rayner, Y Suárez, C Fernández-Hernando	Trends in Endocrinology & Metabolism	2010
Dietary fat intake promotes the development of hepatic steatosis independently from excess caloric consumption in a murine model VE de Meijer, HD Le, JA Meisel, MR Sharif, A Pan, V Nosé, M Puder	Metabolism	2010
Metabolic and Transcriptomic Responses of Weaned Pigs Induced by Different Dietary Amylose and Amylopectin Ratio H Jun, C Daiwen, Y Bing, IA Hansen	PloS one	2010
Pdro, a Protein Associated with Late Endosomes and Lysosomes and Implicated in Cellular Cholesterol Homeostasis P Guillaumot, C Luquain, M Malek, AL Huber, S Brugière, J Garin, D Grunwald, D Régnier, V Pétrilli, E Lefai, SN Manié, SH Caplan	PloS one	2010
Disruption of the Acyl-CoA-binding Protein Gene Delays Hepatic Adaptation to Metabolic Changes at Weaning D Neess, M Bloksgaard, S Bek, AB Marcher, IC Elle, T Helledie, M Due, V Pagmantidis, B Finsen, J Wilbertz, M Kruhøffer, N Færgeman, S Mandrup	The Journal of biological chemistry	2010
Time of Day and Nutrients in Feeding Govern Daily Expression Rhythms of the Gene for Sterol Regulatory Element-binding Protein (SREBP)-1 in the Mouse Liver E Matsumoto, A Ishihara, S Tamai, A Nemoto, K Iwase, T Hiwasa, S Shibata, M Takiguchi	The Journal of biological chemistry	2010
PPARα: energy combustion, hypolipidemia, inflammation and cancer SR Pyper, N Viswakarma, S Yu, JK Reddy	Nuclear receptor signaling	2010
Activation of Sterol Regulatory Element Binding Proteins in the Absence of Scap in Drosophila melanogaster KA Matthews, C Ozdemir, RB Rawson	Genetics	2010
Dietary saponins of sea cucumber alleviate orotic acid-induced fatty liver in rats via PPARα and SREBP-1c signaling XQ Hu, YM Wang, JF Wang, Y Xue, ZJ Li, K Nagao, T Yanagita, CH Xue	Lipids in Health and Disease	2010
Hepatocyte Nuclear Factor 4α Coordinates a Transcription Factor Network Regulating Hepatic Fatty Acid Metabolism CP Martinez-Jimenez, I Kyrmizi, P Cardot, FJ Gonzalez, I Talianidis	Molecular and cellular biology	2010
The TRC8 Ubiquitin Ligase Is Sterol Regulated and Interacts with Lipid and Protein Biosynthetic Pathways JP Lee, A Brauweiler, M Rudolph, JE Hooper, HA Drabkin, RM Gemmill	Molecular cancer research : MCR	2010
ERp57 Modulates STAT3 Signaling from the Lumen of the Endoplasmic Reticulum H Coe, J Jung, J Groenendyk, D Prins, M Michalak	The Journal of biological chemistry	2010
Effect of the feeding system on the fatty acid composition, expression of the Δ9-desaturase, Peroxisome Proliferator-Activated Receptor Alpha, Gamma, and Sterol Regulatory Element Binding Protein 1 genes in the semitendinous muscle of light lambs of the Rasa Aragonesa breed E Dervishi, C Serrano, M Joy, M Serrano, C Rodellar, JH Calvo	BMC veterinary research	2010
Farnesoid X receptor-Acting through bile acids to treat metabolic disorders. Zhang Y	Drugs of the future	2010
Differential expression and function of ABCG1 and ABCG4 during development and aging. Bojanic DD, Tarr PT, Gale GD, Smith DJ, Bok D, Chen B, Nusinowitz S, Lövgren-Sandblom A, Björkhem I, Edwards PA	Journal of lipid research	2010
Curcumin inhibits srebp-2 expression in activated hepatic stellate cells in vitro by reducing the activity of specificity protein-1 Q Kang, A Chen	Endocrinology	2009
Mitochondrial cholesterol loading exacerbates amyloid beta peptide-induced inflammation and neurotoxicity A Fernández, L Llacuna, JC Fernández-Checa, A Colell	The Journal of neuroscience : the official journal of the Society for Neuroscience	2009
Skin-specific deletion of stearoyl-CoA desaturase-1 alters skin lipid composition and protects mice from high fat diet-induced obesity H Sampath, MT Flowers, X Liu, CM Paton, R Sullivan, K Chu, M Zhao, JM Ntambi	The Journal of biological chemistry	2009
A new role for sterol regulatory element binding protein 1 transcription factors in the regulation of muscle mass and muscle cell differentiation V Lecomte, E Meugnier, V Euthine, C Durand, D Freyssenet, G Nemoz, S Rome, H Vidal, E Lefai	Molecular and cellular biology	2009
The ATF6-Met[67]Val substitution is associated with increased plasma cholesterol levels SJ Meex, D Weissglas-Volkov, CJ van der Kallen, DJ Thuerauf, MM van Greevenbroek, CG Schalkwijk, CD Stehouwer, EJ Feskens, L Heldens, TA Ayoubi, MH Hofker, BG Wouters, R Vlietinck, JS Sinsheimer, MR Taskinen, J Kuusisto, M Laakso, TW de Bruin, P Pajukanta, CC Glembotski	Arteriosclerosis, thrombosis, and vascular biology	2009
Sterol regulatory element binding protein 1a regulates hepatic fatty acid partitioning by activating acetyl coenzyme A carboxylase 2 SS Im, LE Hammond, L Yousef, C Nugas-Selby, DJ Shin, YK Seo, LG Fong, SG Young, TF Osborne	Molecular and cellular biology	2009
Pulmonary surfactant: an immunological perspective ZC Chroneos, Z Sever-Chroneos, VL Shepherd	Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology	2009
Deletion of Scap in alveolar type II cells influences lung lipid homeostasis and identifies a compensatory role for pulmonary lipofibroblasts V Besnard, SE Wert, MT Stahlman, AD Postle, Y Xu, M Ikegami, JA Whitsett	The Journal of biological chemistry	2009
Molecular mechanisms involved in NAFLD progression M Malaguarnera, MD Rosa, F Nicoletti, L Malaguarnera	Journal of Molecular Medicine	2009
Second-hand smoke stimulates lipid accumulation in the liver by modulating AMPK and SREBP-1 H Yuan, JY Shyy, M Martins-Green	Journal of Hepatology	2009
Molecular consequences of altered neuronal cholesterol biosynthesis Z Korade, AK Kenworthy, K Mirnics	Journal of Neuroscience Research	2009
Salt-inducible kinase regulates hepatic lipogenesis by controlling SREBP-1c phosphorylation YS Yoon, WY Seo, MW Lee, ST Kim, SH Koo	The Journal of biological chemistry	2009
An Emerging Role of mTOR in Lipid Biosynthesis M Laplante, DM Sabatini	Current Biology	2009
Hepatic effects of a methionine–choline-deficient diet in hepatocyte RXRα-null mice MA Gyamfi, Y Tanaka, L He, CD Klaassen, YJ Wan	Toxicology and Applied Pharmacology	2009
Intersection of the unfolded protein response and hepatic lipid metabolism AH Lee, LH Glimcher	Cellular and Molecular Life Sciences	2009
Genome-wide analysis of SREBP-1 binding in mouse liver chromatin reveals a preference for promoter proximal binding to a new motif YK Seo, HK Chong, AM Infante, SS Im, X Xie, TF Osborne	Proceedings of the National Academy of Sciences	2009
From Sugar to Fat LH Glimcher, AH Lee	Annals of the New York Academy of Sciences	2009
Dissecting the role of insulin resistance in the metabolic syndrome JT Haas, SB Biddinger	Current Opinion in Lipidology	2009
Desmosterol can replace cholesterol in sustaining cell proliferation and regulating the SREBP pathway in a sterol-Δ24-reductase-deficient cell line S Rodríguez-Acebes, P la Cueva, C Fernández-Hernando, AJ Ferruelo, MA Lasunción, RB Rawson, J Martínez-Botas, D Gómez-Coronado	Biochemical Journal	2009
Central nervous system: cholesterol turnover, brain development and neurodegeneration JM Dietschy	Biological Chemistry	2009
Thyroid hormone β receptor activation has additive cholesterol lowering activity in combination with atorvastatin in rabbits, dogs and monkeys BR Ito, BH Zhang, EE Cable, X Song, JM Fujitaki, DA MacKenna, CE Wilker, B Chi, PD van Poelje, DL Linemeyer, MD Erion	British Journal of Pharmacology	2009
Feeding pregnant rats a low-protein diet alters the hepatic expression of SREBP-1c in their offspring via a glucocorticoid-related mechanism A Erhuma, S McMullen, SC Langley-Evans, AJ Bennett	Endocrine	2009
Regulation of steroid 5-α reductase type 2 (Srd5a2) by sterol regulatory element binding proteins and statin YK Seo, B Zhu, TI Jeon, TF Osborne	Experimental Cell Research	2009
Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL MS Brown, JL Goldstein	Journal of lipid research	2009
Carbohydrate response element binding protein gene expression is positively regulated by thyroid hormone K Hashimoto, E Ishida, S Matsumoto, S Okada, M Yamada, T Satoh, T Monden, M Mori	Endocrinology	2009
Bile acids as regulatory molecules PB Hylemon, H Zhou, WM Pandak, S Ren, G Gil, P Dent	Journal of lipid research	2009
Accelerated fatty acid oxidation in muscle averts fasting-induced hepatic steatosis in SJL/J mice HP Guan, JL Goldstein, MS Brown, G Liang	The Journal of biological chemistry	2009
Deletion of ELOVL5 leads to fatty liver through activation of SREBP-1c in mice YA Moon, RE Hammer, JD Horton	Journal of lipid research	2009
Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been TF Osborne, PJ Espenshade	Genes & development	2009
Curcumin suppresses expression of low-density lipoprotein (LDL) receptor, leading to the inhibition of LDL-induced activation of hepatic stellate cells Q Kang, A Chen	British Journal of Pharmacology	2009
Identification of novel genes and pathways regulating SREBP transcriptional activity S Chatterjee, JD Szustakowski, NR Nanguneri, C Mickanin, MA Labow, A Nohturfft, KK Dev, R Sivasankaran	PloS one	2009
Insulin enhances post-translational processing of nascent SREBP-1c by promoting its phosphorylation and association with COPII vesicles CR Yellaturu, X Deng, LM Cagen, HG Wilcox, CM 2nd, SA Siddiqi, EA Park, R Raghow, MB Elam	The Journal of biological chemistry	2009
Is alcohol beneficial or harmful for cardioprotection? R Lakshman, M Garige, M Gong, L Leckey, R Varatharajalu, S Zakhari	Genes & Nutrition	2009
Peroxisome deficiency causes a complex phenotype because of hepatic SREBP/Insig dysregulation associated with endoplasmic reticulum stress WJ Kovacs, KN Tape, JE Shackelford, TM Wikander, MJ Richards, SJ Fliesler, SK Krisans, PL Faust	The Journal of biological chemistry	2009
Phosphorylation and protein-protein interactions in PXR-mediated CYP3A repression SR Pondugula, H Dong, T Chen	Expert Opinion on Drug Metabolism & Toxicology	2009
Microarray analysis of hepatic gene expression identifies new genes involved in steatotic liver N Guillén, MA Navarro, C Arnal, E Noone, JM Arbonés-Mainar, S Acín, JC Surra, P Muniesa, HM Roche, J Osada	Physiological genomics	2009
Genetic evidence for a role of adiponutrin in the metabolism of apolipoprotein B-containing lipoproteins B Kollerits, S Coassin, ND Beckmann, A Teumer, S Kiechl, A Döring, M Kavousi, SC Hunt, C Lamina, B Paulweber, Z Kutalik, M Nauck, CM van Duijn, IM Heid, J Willeit, A Brandstätter, TD Adams, V Mooser, YS Aulchenko, H Völzke, F Kronenberg	Human Molecular Genetics	2009
Effect of CAR activation on selected metabolic pathways in normal and hyperlipidemic mouse livers T Rezen, V Tamasi, A Lövgren-Sandblom, I Björkhem, UA Meyer, D Rozman	BMC Genomics	2009
The INSIG2 rs7566605 genetic variant does not play a major role in obesity in a sample of 24,722 individuals from four cohorts J Bressler, M Fornage, CL Hanis, WH Kao, CE Lewis, R McPherson, R Dent, TH Mosley, LA Pennacchio, E Boerwinkle	BMC Medical Genetics	2009
A comparative analysis of genistein and daidzein in affecting lipid metabolism in rat liver Y Takahashi, TO Odbayar, T Ide	Journal of Clinical Biochemistry and Nutrition	2009
Influence of the cystic fibrosis transmembrane conductance regulator on expression of lipid metabolism-related genes in dendritic cells Y Xu, C Tertilt, A Krause, LE Quadri, RG Crystal, S Worgall	Respiratory Research	2009
Perturbations of membrane structure by cholesterol and cholesterol derivatives are determined by sterol orientation BN Olsen, PH Schlesinger, NA Baker	Journal of the American Chemical Society	2009
The LDL receptor JL Goldstein, MS Brown	Arteriosclerosis, thrombosis, and vascular biology	2009
MUC1-induced alterations in a lipid metabolic gene network predict response of human breast cancers to tamoxifen treatment SP Pitroda, NN Khodarev, MA Beckett, DW Kufe, RR Weichselbaum	Proceedings of the National Academy of Sciences	2009
Oxidative stress-mediated mitochondrial dysfunction contributes to angiotensin II-induced nonalcoholic fatty liver disease in transgenic Ren2 rats Y Wei, SE Clark, JP Thyfault, GM Uptergrove, W Li, AT Whaley-Connell, CM Ferrario, JR Sowers, JA Ibdah	The American Journal of Pathology	2009
Antagonism of secreted PCSK9 increases low density lipoprotein receptor expression in HepG2 cells MC McNutt, HJ Kwon, C Chen, JR Chen, JD Horton, TA Lagace	The Journal of biological chemistry	2009
Docosahexaenoic Acid Activates Some SREBP-2 Targets Independent of Cholesterol and ER Stress in SW620 Colon Cancer Cells GL Størvold, KG Fleten, CG Olsen, T Follestad, HE Krokan, SA Schønberg	Lipids	2009
The Role of Protease Inhibitors in the Pathogenesis of HIV-Associated Lipodystrophy: Cellular Mechanisms and Clinical Implications OP Flint, MA Noor, PW Hruz, PB Hylemon, K Yarasheski, DP Kotler, RA Parker, A Bellamine	Toxicologic pathology	2009
Rats selectively bred for low aerobic capacity have reduced hepatic mitochondrial oxidative capacity and susceptibility to hepatic steatosis and injury: Aerobic capacity and hepatic mitochondria JP Thyfault, RS Rector, GM Uptergrove, SJ Borengasser, EM Morris, Y Wei, MJ Laye, CF Burant, NR Qi, SE Ridenhour, LG Koch, SL Britton, JA Ibdah	The Journal of Physiology	2009
Ablation of ARNT/HIF1β in Liver Alters Gluconeogenesis, Lipogenic Gene Expression, and Serum Ketones XL Wang, R Suzuki, K Lee, T Tran, JE Gunton, AK Saha, ME Patti, A Goldfine, NB Ruderman, FJ Gonzalez, CR Kahn	Cell Metabolism	2009
Cell and molecular mechanisms of insulin-induced angiogenesis Y Liu, M Petreaca, M Martins-Green	Journal of Cellular and Molecular Medicine	2009
Complex assembly on the human CYP17 promoter MB Sewer, S Jagarlapudi	Molecular and Cellular Endocrinology	2009
Targeted lipidomic analysis of oxysterols in the embryonic central nervous system Y Wang, KM Sousa, K Bodin, S Theofilopoulos, P Sacchetti, M Hornshaw, G Woffendin, K Karu, J Sjövall, E Arenas, WJ Griffiths	Molecular BioSystems	2009
Lupin protein compared to casein lowers the LDL cholesterol:HDL cholesterol-ratio of hypercholesterolemic adults K Weiße, C Brandsch, B Zernsdorf, GS Nembongwe, K Hofmann, K Eder, GI Stangl	European Journal of Nutrition	2009
Differential Expression of Lipid Metabolism Related Genes in Porcine Muscle Tissue Leading to Different Intramuscular Fat Deposition SM Zhao, LJ Ren, L Chen, X Zhang, ML Cheng, WZ Li, YY Zhang, SZ Gao	Lipids	2009
ELT-2 is the predominant transcription factor controlling differentiation and function of the C. elegans intestine, from embryo to adult JD McGhee, T Fukushige, MW Krause, SE Minnema, B Goszczynski, J Gaudet, Y Kohara, O Bossinger, Y Zhao, J Khattra, M Hirst, SJ Jones, MA Marra, P Ruzanov, A Warner, R Zapf, DG Moerman, JM Kalb	Developmental Biology	2009
The plasma lipidomic signature of nonalcoholic steatohepatitis P Puri, MM Wiest, O Cheung, F Mirshahi, C Sargeant, HK Min, MJ Contos, RK Sterling, M Fuchs, H Zhou, SM Watkins, AJ Sanyal	Hepatology	2009
Cholesterol-Dependent Anaplasma phagocytophilum Exploits the Low-Density Lipoprotein Uptake Pathway Q Xiong, M Lin, Y Rikihisa, J Coburn	PLoS pathogens	2009
Involvement of 4E-BP1 in the Protection Induced by HDLs on Pancreatic β-Cells J Pétremand, N Bulat, AC Butty, C Poussin, S Rütti, K Au, S Ghosh, V Mooser, B Thorens, JY Yang, C Widmann, G Waeber	Molecular Endocrinology	2009
New insights into the molecular mechanisms underlying effects of estrogen on cholesterol gallstone formation HH Wang, M Liu, DJ Clegg, P Portincasa, DQ Wang	Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids	2009
Down-Regulation of Hepatic HNF4α Gene Expression during Hyperinsulinemia via SREBPs X Xie, H Liao, H Dang, W Pang, Y Guan, X Wang, JY Shyy, Y Zhu, FM Sladek	Molecular Endocrinology	2009
Dislocation of HMG-CoA Reductase and Insig-1, Two Polytopic Endoplasmic Reticulum Proteins, En Route to Proteasomal Degradation GS Leichner, R Avner, D Harats, J Roitelman, T Sommer	Molecular biology of the cell	2009
Aspergillus fumigatus metabolism: Clues to mechanisms of in vivo fungal growth and virulence SD Willger, N Grahl, SD Willger, N Grahl, RA Cramer	Medical Mycology	2009
Bezafibrate at Clinically Relevant Doses Decreases Serum/Liver Triglycerides via Down-Regulation of Sterol Regulatory Element-Binding Protein-1c in Mice: A Novel Peroxisome Proliferator-Activated Receptor α-Independent Mechanism T Nakajima, N Tanaka, H Kanbe, A Hara, Y Kamijo, X Zhang, FJ Gonzalez, T Aoyama	Molecular pharmacology	2009
Hepatocyte Nuclear Factor 1α Plays a Critical Role in PCSK9 Gene Transcription and Regulation by the Natural Hypocholesterolemic Compound Berberine H Li, B Dong, SW Park, HS Lee, W Chen, J Liu	The Journal of biological chemistry	2009
Hepatitis C Virus Nonstructural 4B Protein Modulates Sterol Regulatory Element-binding Protein Signaling via the AKT Pathway CY Park, HJ Jun, T Wakita, JH Cheong, SB Hwang	The Journal of biological chemistry	2009
Adipogenic and energy metabolism gene networks in longissimus lumborum during rapid post-weaning growth in Angus and Angus × Simmental cattle fed high-starch or low-starch diets DE Graugnard, P Piantoni, M Bionaz, LL Berger, DB Faulkner, JJ Loor	BMC Genomics	2009
Sterol-mediated Regulation of Human Lipin 1 Gene Expression in Hepatoblastoma Cells K Ishimoto, H Nakamura, K Tachibana, D Yamasaki, A Ota, K Hirano, T Tanaka, T Hamakubo, J Sakai, T Kodama, T Doi	The Journal of biological chemistry	2009
Regulated Endoplasmic Reticulum-associated Degradation of a Polytopic Protein Y Ikeda, GN DeMartino, MS Brown, JN Lee, JL Goldstein, J Ye	The Journal of biological chemistry	2009
Hepatitis C Virus Proteins Induce Lipogenesis and Defective Triglyceride Secretion in Transgenic Mice H Lerat, HL Kammoun, I Hainault, E Mérour, MR Higgs, C Callens, SM Lemon, F Foufelle, JM Pawlotsky	The Journal of biological chemistry	2009
EGFR Signaling Through an Akt-SREBP-1–Dependent, Rapamycin-Resistant Pathway Sensitizes Glioblastomas to Antilipogenic Therapy D Guo, RM Prins, J Dang, D Kuga, A Iwanami, H Soto, KY Lin, TT Huang, D Akhavan, MB Hock, S Zhu, AA Kofman, SJ Bensinger, WH Yong, HV Vinters, S Horvath, AD Watson, JG Kuhn, HI Robins, MP Mehta, PY Wen, LM DeAngelis, MD Prados, IK Mellinghoff, TF Cloughesy, PS Mischel	Science signaling	2009
Lipoproteins, cholesterol homeostasis and cardiac health. Daniels TF, Killinger KM, Michal JJ, Wright RW Jr, Jiang Z	International journal of biological sciences	2009
SREBP-2 Regulates Gut Peptide Secretion through Intestinal Bitter Taste Receptor Signaling in Mice Tae-Il Jeon 1, Bing Zhu 1,2, Jarrod L. Larson 1, and Timothy F. Osborne 1,3	Journal of Clinical Investigation	2008
Overindulgence and metabolic syndrome: Is FoxO1 a missing link? Janet D. Sparks and Charles E. Sparks	Journal of Clinical Investigation	2008
From fatty streak to fatty liver: 33 years of joint publications in the JCI Joseph L. Goldstein and Michael S. Brown	Journal of Clinical Investigation	2008
Increased cellular free cholesterol in macrophage-specific Abca1 knock-out mice enhances pro-inflammatory response of macrophages X Zhu, JY Lee, JM Timmins, JM Brown, E Boudyguina, A Mulya, AK Gebre, MC Willingham, EM Hiltbold, N Mishra, N Maeda, JS Parks	The Journal of biological chemistry	2008
25-Hydroxycholesterol-3-sulfate regulates macrophage lipid metabolism via the LXR/SREBP-1 signaling pathway Y Ma, L Xu, D Rodriguez-Agudo, X Li, DM Heuman, PB Hylemon, WM Pandak, S Ren	American journal of physiology. Endocrinology and metabolism	2008
Cell type-dependent pro- and anti-inflammatory role of signal transducer and activator of transcription 3 in alcoholic liver injury N Horiguchi, L Wang, P Mukhopadhyay, O Park, WI Jeong, F Lafdil, D Osei-Hyiaman, A Moh, XY Fu, P Pacher, G Kunos, B Gao	Gastroenterology	2008
Liver x receptor: a novel therapeutic target MB Patel, NA Oza, IS Anand, SS Deshpande, CN Patel	Indian journal of pharmaceutical sciences	2008
Inactivation of Hepatic Foxo1 by Insulin Signaling Is Required for Adaptive Nutrient Homeostasis and Endocrine Growth Regulation XC Dong, KD Copps, S Guo, Y Li, R Kollipara, RA DePinho, MF White	Cell Metabolism	2008
Identification of Adropin as a Secreted Factor Linking Dietary Macronutrient Intake with Energy Homeostasis and Lipid Metabolism KG Kumar, JL Trevaskis, DD Lam, GM Sutton, RA Koza, VN Chouljenko, KG Kousoulas, PM Rogers, RA Kesterson, M Thearle, AW Ferrante, RL Mynatt, TP Burris, JZ Dong, HA Halem, MD Culler, LK Heisler, JM Stephens, AA Butler	Cell Metabolism	2008
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1: A Link Between Insulin and Lipid Metabolism AM DeAngelis, G Heinrich, T Dai, TA Bowman, PR Patel, SJ Lee, EG Hong, DY Jung, A Assmann, RN Kulkarni, JK Kim, SM Najjar	Diabetes	2008
Fructose consumption: potential mechanisms for its effects to increase visceral adiposity and induce dyslipidemia and insulin resistance KL Stanhope, PJ Havel	Current Opinion in Lipidology	2008
Hepatic Insulin Resistance Is Sufficient to Produce Dyslipidemia and Susceptibility to Atherosclerosis SB Biddinger, A Hernandez-Ono, C Rask-Madsen, JT Haas, JO Alemán, R Suzuki, EF Scapa, C Agarwal, MC Carey, G Stephanopoulos, DE Cohen, GL King, HN Ginsberg, CR Kahn	Cell Metabolism	2008
Androgen synthesis in adrenarche WL Miller	Reviews in Endocrine and Metabolic Disorders	2008
The blind men 'see' the elephant-the many faces of fatty liver disease MG Sanal	World journal of gastroenterology : WJG	2008
Targeted depletion of hepatic ACAT2-driven cholesterol esterification reveals a non-biliary route for fecal neutral sterol loss JM Brown, TA 3rd, HM Alger, JK Sawyer, TL Smith, K Kelley, R Shah, MD Wilson, MA Davis, RG Lee, MJ Graham, RM Crooke, LL Rudel	The Journal of biological chemistry	2008
Feedback regulation of cholesterol synthesis: sterol-accelerated ubiquitination and degradation of HMG CoA reductase RA DeBose-Boyd	Cell Research	2008
Endocrine and paracrine role of bile acids V Keitel, R Kubitz, D Häussinger	World journal of gastroenterology : WJG	2008
Plasma PCSK9 preferentially reduces liver LDL receptors in mice A Grefhorst, MC McNutt, TA Lagace, JD Horton	Journal of lipid research	2008
Nonalcoholic fatty liver disease: an overview of current insights in pathogenesis, diagnosis and treatment TC Schreuder, BJ Verwer, CM van Nieuwkerk, CJ Mulder	World journal of gastroenterology : WJG	2008
Mechanisms of antidiabetogenic and body weight-lowering effects of estrogen in high-fat diet-fed mice G Bryzgalova, L Lundholm, N Portwood, JA Gustafsson, A Khan, S Efendic, K Dahlman-Wright	American journal of physiology. Endocrinology and metabolism	2008
Proto-oncogene FBI-1 (Pokemon) and SREBP-1 synergistically activate transcription of fatty-acid synthase gene (FASN) WI Choi, BN Jeon, H Park, JY Yoo, YS Kim, DI Koh, MH Kim, YR Kim, CE Lee, KS Kim, TF Osborne, MW Hur	The Journal of biological chemistry	2008
Maternal hypercholesterolemia leads to activation of endogenous cholesterol synthesis in the offspring N Goharkhay, EH Tamayo, H Yin, GD Hankins, GR Saade, M Longo	American Journal of Obstetrics and Gynecology	2008
Elevated hepatic fatty acid elongase-5 activity affects multiple pathways controlling hepatic lipid and carbohydrate composition Y Wang, M Torres-Gonzalez, S Tripathy, D Botolin, B Christian, DB Jump	Journal of lipid research	2008
Insulin-like growth factor-1 coordinately induces the expression of fatty acid and cholesterol biosynthetic genes in murine C2C12 myoblasts CR Bhasker, T Friedmann	BMC Genomics	2008
Regulation of cholesterologenesis by the oxysterol receptor, LXRalpha Y Wang, PM Rogers, C Su, G Varga, KR Stayrook, TP Burris	The Journal of biological chemistry	2008
Gene networks driving bovine milk fat synthesis during the lactation cycle M Bionaz, JJ Loor	BMC Genomics	2008
Expression profiling of hepatic genes associated with lipid metabolism in nephrotic rats Y Zhou, X Zhang, L Chen, J Wu, H Dang, M Wei, Y Fan, Y Zhang, Y Zhu, N Wang, MD Breyer, Y Guan	American journal of physiology. Renal physiology	2008
Identification of twenty-three mutations in fission yeast Scap that constitutively activate SREBP AL Hughes, EV Stewart, PJ Espenshade	Journal of lipid research	2008
N-3 polyunsaturated fatty acid regulation of hepatic gene transcription DB Jump	Current Opinion in Lipidology	2008
Docosahexaenoic acid (DHA) and hepatic gene transcription DB Jump, D Botolin, Y Wang, J Xu, O Demeure, B Christian	Chemistry and Physics of Lipids	2008
Txnip balances metabolic and growth signaling via PTEN disulfide reduction ST Hui, AM Andres, AK Miller, NJ Spann, DW Potter, NM Post, AZ Chen, S Sachithanantham, DY Jung, JK Kim, RA Davis	Proceedings of the National Academy of Sciences	2008
The effect of 24S-hydroxycholesterol on cholesterol homeostasis in neurons: quantitative changes to the cortical neuron proteome Y Wang, S Muneton, J Sjövall, JN Jovanovic, WJ Griffiths	Journal of Proteome Research	2008
The Sterolgene v0 cDNA microarray: a systemic approach to studies of cholesterol homeostasis and drug metabolism T Rezen, P Juvan, KF Tacer, D Kuzman, A Roth, D Pompon, LP Aggerbeck, UA Meyer, D Rozman	BMC Genomics	2008
Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet ME Rinella, MS Elias, RR Smolak, T Fu, J Borensztajn, RM Green	Journal of lipid research	2008
Acute clozapine exposure in vivo induces lipid accumulation and marked sequential changes in the expression of SREBP, PPAR, and LXR target genes in rat liver J Fernø, AO Vik-Mo, G Jassim, B Håvik, K Berge, S Skrede, OA Gudbrandsen, J Waage, N Lunder, S Mørk, RK Berge, HA Jørgensen, VM Steen	Psychopharmacology	2008
Prolactin Regulation of Mammary Gland Development SR Oakes, RL Rogers, MJ Naylor, CJ Ormandy	Journal of Mammary Gland Biology and Neoplasia	2008
Regulation of Hepatic Lipogenesis by the Transcription Factor XBP1 AH Lee, EF Scapa, DE Cohen, LH Glimcher	Science	2008
Liver-Specific Deletion of Protein-Tyrosine Phosphatase 1B (PTP1B) Improves Metabolic Syndrome and Attenuates Diet-Induced Endoplasmic Reticulum Stress M Delibegovic, D Zimmer, C Kauffman, K Rak, EG Hong, YR Cho, JK Kim, BB Kahn, BG Neel, KK Bence	Diabetes	2008
Development of Nonalcoholic Steatohepatitis in Insulin-Resistant Liver-Specific S503A Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 Mutant Mice SJ Lee, G Heinrich, L Fedorova, QY Al–Share, KJ Ledford, MA Fernstrom, MF McInerney, SK Erickson, C Gatto–Weis, SM Najjar	Gastroenterology	2008
Global metabolic effects of glycerol kinase overexpression in rat hepatoma cells G Sriram, L Rahib, JS He, AE Campos, LS Parr, JC Liao, KM Dipple	Molecular Genetics and Metabolism	2008
Differential expression of hepatic genes involved in cholesterol homeostasis in high- and low-responding strains of laboratory opossums J Chan, LM Donalson, RS Kushwaha, S Ferdinandusse, JF VandeBerg, JL VandeBerg	Metabolism	2008
STAT3 Regulates ABCA3 Expression and Influences Lamellar Body Formation in Alveolar Type II Cells Y Matsuzaki, V Besnard, JC Clark, Y Xu, SE Wert, M Ikegami, JA Whitsett	American journal of respiratory cell and molecular biology	2008
Significant association of SREBP-2genetic polymorphisms with avascular necrosis in the Korean population TH Kim, JI Baek, JM Hong, SJ Choi, HJ Lee, HJ Cho, EK Park, UK Kim, SY Kim	BMC Medical Genetics	2008
Genome-Wide Occupancy of SREBP1 and Its Partners NFY and SP1 Reveals Novel Functional Roles and Combinatorial Regulation of Distinct Classes of Genes BD Reed, AE Charos, AM Szekely, SM Weissman, M Snyder, WN Frankel	PLoS genetics	2008
Hormonal Regulation of Testicular Steroid and Cholesterol Homeostasis SM Eacker, N Agrawal, K Qian, HL Dichek, EY Gong, K Lee, RE Braun	Molecular Endocrinology	2008
Dyslipidemia and Atherosclerosis Induced by Chronic Intermittent Hypoxia Are Attenuated by Deficiency of Stearoyl Coenzyme A Desaturase V Savransky, J Jun, J Li, A Nanayakkara, S Fonti, AB Moser, KE Steele, MA Schweitzer, SP Patil, S Bhanot, AR Schwartz, VY Polotsky	Circulation research	2008
Anticancer effects of Chinese red yeast rice versus monacolin K alone on colon cancer cells MY Hong, NP Seeram, Y Zhang, D Heber	The Journal of Nutritional Biochemistry	2008
Effect of dietary conjugated linoleic acid isomers on lipid metabolism in hamsters fed high-carbohydrate and high-fat diets EJ Tarling, KJ Ryan, AJ Bennett, AM Salter	British Journal of Nutrition	2008
Unfolding Lipid Metabolism JD Horton	Science	2008
Intramembrane Processing by Signal Peptide Peptidase Regulates the Membrane Localization of Hepatitis C Virus Core Protein and Viral Propagation K Okamoto, Y Mori, Y Komoda, T Okamoto, M Okochi, M Takeda, T Suzuki, K Moriishi, Y Matsuura	Journal of virology	2008
Statins and primary prevention: is all the evidence in? Rashid S, Francis GA	The Canadian journal of cardiology	2008
The Citrus Flavonoids Hesperetin and Nobiletin Differentially Regulate Low Density Lipoprotein Receptor Gene Transcription in HepG2 Liver Cells- Morin B, Nichols LA, Zalasky KM, Davis JW, Manthey JA, Holland LJ	The Journal of nutrition	2008
Fasting-dependent glucose and lipid metabolic response through hepatic sirtuin 1 JT Rodgers, P Puigserver	Proceedings of the National Academy of Sciences	2007
The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome KF Petersen, S Dufour, DB Savage, S Bilz, G Solomon, S Yonemitsu, GW Cline, D Befroy, L Zemany, BB Kahn, X Papademetris, DL Rothman, GI Shulman	Proceedings of the National Academy of Sciences	2007
Blockade of MCH1 receptor signalling ameliorates obesity and related hepatic steatosis in ovariectomized mice A Gomori, A Ishihara, M Ito, H Matsushita, M Ito, S Mashiko, H Iwaasa, M Matsuda, MA Bednarek, S Qian, DJ Macneil, A Kanatani	British Journal of Pharmacology	2007
Absence of stearoyl-CoA desaturase-1 ameliorates features of the metabolic syndrome in LDLR-deficient mice ML MacDonald, RR Singaraja, N Bissada, P Ruddle, R Watts, JM Karasinska, WT Gibson, C Fievet, JE Vance, B Staels, MR Hayden	Journal of lipid research	2007
SLEEP DISORDERED BREATHING AND METABOLIC EFFECTS: EVIDENCE FROM ANIMAL MODELS J Jun, VY Polotsky	Sleep Medicine Clinics	2007
Distinct C/EBPalpha motifs regulate lipogenic and gluconeogenic gene expression in vivo TA Pedersen, O Bereshchenko, S Garcia-Silva, O Ermakova, E Kurz, S Mandrup, BT Porse, C Nerlov	The EMBO Journal	2007
SREBP-1c and TFE3, energy transcription factors that regulate hepatic insulin signaling H Shimano	Journal of Molecular Medicine	2007
PGC-1beta controls mitochondrial metabolism to modulate circadian activity, adaptive thermogenesis, and hepatic steatosis J Sonoda, IR Mehl, LW Chong, RR Nofsinger, RM Evans	Proceedings of the National Academy of Sciences	2007
Lipid Synthesis in Lactation: Diet and the Fatty Acid Switch MC Rudolph, MC Neville, SM Anderson	Journal of Mammary Gland Biology and Neoplasia	2007
Fatty Acid Supplied as Triglyceride Regulates SRE-Mediated Gene Expression as Efficiently as Free Fatty Acids N Densupsoontorn, TS Worgall, T Seo, H Hamai, RJ Deckelbaum	Lipids	2007
Bile Acid Transporters: Structure, Function, Regulation and Pathophysiological Implications WA Alrefai, RK Gill	Pharmaceutical Research	2007
The liver plays a key role in whole body sterol accretion of the neonatal Golden Syrian hamster L Yao, PS Horn, JE Heubi, LA Woollett	Biochimica et Biophysica Acta	2007
Increased expression of CD14 in macrophages after inhibition of the cholesterol biosynthetic pathway by lovastatin T Frey, AD Maio	Molecular Medicine	2007
The effect of trans-10,cis-12 conjugated linoleic acid on lipogenesis is tissue dependent in hamsters I Churruca, A Fernández-Quintela, A Zabala, MT Macarulla, V Navarro, VM Rodríguez, E Simón, F Milagro, MP Portillo	Genes & Nutrition	2007
Gene expression and biological processes influenced by deletion of Stat3 in pulmonary type II epithelial cells Y Xu, M Ikegami, Y Wang, Y Matsuzaki, JA Whitsett	BMC Genomics	2007
Lean gene and the clock machine KM Ramsey, J Bass	Proceedings of the National Academy of Sciences	2007
Loss of Nocturnin, a circadian deadenylase, confers resistance to hepatic steatosis and diet-induced obesity CB Green, N Douris, S Kojima, CA Strayer, J Fogerty, D Lourim, SR Keller, JC Besharse	Proceedings of the National Academy of Sciences	2007
Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: oxysterols block transport by binding to Insig A Radhakrishnan, Y Ikeda, HJ Kwon, MS Brown, JL Goldstein	Proceedings of the National Academy of Sciences	2007
Key stages in mammary gland development. Secretory activation in the mammary gland: it's not just about milk protein synthesis! SM Anderson, MC Rudolph, JL McManaman, MC Neville	Breast Cancer Research	2007
Prenatal exposure to a low-protein diet programs disordered regulation of lipid metabolism in the aging rat A Erhuma, AM Salter, DV Sculley, SC Langley-Evans, AJ Bennett	American journal of physiology. Endocrinology and metabolism	2007
The role of protease inhibitors in the pathogenesis of HIV-associated insulin resistance: Cellular mechanisms and clinical implications MA Noor	Current HIV/AIDS Reports	2007
Prenatal exposure to undernutrition and programming of responses to high-fat feeding in the rat A Erhuma, L Bellinger, SC Langley-Evans, AJ Bennett	British Journal of Nutrition	2007
Cholesterol: from feeding to gene regulation C Martini, V Pallottini	Genes & Nutrition	2007
Novel Role of Soluble Epoxide Hydrolase in Regulating Cholesterol in Mammalian Cells A Enayetallah, L Cao, DF Grant	The Open Drug Metabolism Journal	2007
Evidence for Positive Selection in the C-terminal Domain of the Cholesterol Metabolism Gene PCSK9 Based on Phylogenetic Analysis in 14 Primate Species K Ding, SJ McDonough, IJ Kullo, M Hahn	PloS one	2007
Inability to fully suppress sterol synthesis rates with exogenous sterol in embryonic and extraembyronic fetal tissues L Yao, K Jenkins, PS Horn, MH Lichtenberg, LA Woollett	Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids	2007
Cooperative Interaction between Hepatocyte Nuclear Factor 4α and GATA Transcription Factors Regulates ATP-Binding Cassette Sterol Transporters ABCG5 and ABCG8 K Sumi, T Tanaka, A Uchida, K Magoori, Y Urashima, R Ohashi, H Ohguchi, M Okamura, H Kudo, K Daigo, T Maejima, N Kojima, I Sakakibara, S Jiang, G Hasegawa, I Kim, TF Osborne, M Naito, FJ Gonzalez, T Hamakubo, T Kodama, J Sakai	Molecular and cellular biology	2007
Chromatin Remodeling Complex Interacts with ADD1/SREBP1c To Mediate Insulin-Dependent Regulation of Gene Expression YS Lee, DH Sohn, D Han, HW Lee, RH Seong, JB Kim	Molecular and cellular biology	2007
Hepatitis C Virus Induces Proteolytic Cleavage of Sterol Regulatory Element Binding Proteins and Stimulates Their Phosphorylation via Oxidative Stress G Waris, DJ Felmlee, F Negro, A Siddiqui	Journal of virology	2007
Novel Transcriptional Activities of Vitamin E: Inhibition of Cholesterol Biosynthesis S Valastyan, V Thakur, A Johnson, K Kumar, D Manor	Biochemistry	2007
4-Methyl Sterols Regulate Fission Yeast SREBP-Scap under Low Oxygen and Cell Stress AL Hughes, CY Lee, CM Bien, PJ Espenshade	The Journal of biological chemistry	2007
Signaling mechanisms in alcoholic liver injury: role of transcription factors, kinases and heat shock proteins. Mandrekar P	World Journal of Gastroenterology	2007
Liver X receptor antagonist reduces lipid formation and increases glucose metabolism in myotubes from lean, obese and type 2 diabetic individuals. Kase ET, Thoresen GH, Westerlund S, Højlund K, Rustan AC, Gaster M	Diabetologia	2007
Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin Luke J. Engelking, Bret M. Evers, James A. Richardson, Joseph L. Goldstein, Michael S. Brown, and Guosheng Liang	Journal of Clinical Investigation	2006
Liver X receptors as integrators of metabolic and inflammatory signaling N Zelcer, P Tontonoz	Journal of Clinical Investigation	2006
Insulin regulation of cholesterol 7alpha-hydroxylase expression in human hepatocytes: roles of forkhead box O1 and sterol regulatory element-binding protein 1c T Li, X Kong, E Owsley, E Ellis, S Strom, JY Chiang	The Journal of biological chemistry	2006
Signalling mechanisms linking hepatic glucose and lipid metabolism MO Weickert, AF Pfeiffer	Diabetologia	2006
LDL and cAMP cooperate to regulate the functional expression of the LRP in rat ovarian granulosa cells S Azhar, S Medicherla, WJ Shen, Y Fujioka, LG Fong, E Reaven, AD Cooper	Journal of lipid research	2006
Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases WC Hallows, S Lee, JM Denu	Proceedings of the National Academy of Sciences	2006
Regulation of GLUT4 gene expression by SREBP-1c in adipocytes SS Im, SK Kwon, SY Kang, TH Kim, HI Kim, MW Hur, KS Kim, YH Ahn	Biochemical Journal	2006
Keratinocyte growth factor induces lipogenesis in alveolar type II cells through a sterol regulatory element binding protein-1c-dependent pathway Y Chang, K Edeen, X Lu, MD Leon, RJ Mason	American journal of respiratory cell and molecular biology	2006
Drug-induced activation of SREBP-controlled lipogenic gene expression in CNS-related cell lines: marked differences between various antipsychotic drugs J Fernø, S Skrede, AO Vik-Mo, B Håvik, VM Steen	BMC neuroscience	2006
Stearoyl-coenzyme A desaturase 1 deficiency protects against hypertriglyceridemia and increases plasma high-density lipoprotein cholesterol induced by liver X receptor activation K Chu, M Miyazaki, WC Man, JM Ntambi	Molecular and cellular biology	2006
Polymorphisms in the gene encoding sterol regulatory element-binding factor-1c are associated with type 2 diabetes AH Harding, RJ Loos, J Luan, S O'Rahilly, NJ Wareham, I Barroso	Diabetologia	2006
Identification of inflammatory gene modules based on variations of human endothelial cell responses to oxidized lipids PS Gargalovic, M Imura, B Zhang, NM Gharavi, MJ Clark, J Pagnon, WP Yang, A He, A Truong, S Patel, SF Nelson, S Horvath, JA Berliner, TG Kirchgessner, AJ Lusis	Proceedings of the National Academy of Sciences	2006
Insulin induction of glucokinase and fatty acid synthase in hepatocytes: analysis of the roles of sterol-regulatory-element-binding protein-1c and liver X receptor F Hansmannel, S Mordier, PB Iynedjian	Biochemical Journal	2006
Primate-specific evolution of an LDLR enhancer Q Wang, S Prabhakar, Q Wang, AM Moses, S Chanan, M Brown, MB Eisen, JF Cheng, EM Rubin, D Boffelli	Genome biology	2006
Endocrine functions of bile acids SM Houten, M Watanabe, J Auwerx	The EMBO Journal	2006
Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast BL Todd, EV Stewart, JS Burg, AL Hughes, PJ Espenshade	Molecular and cellular biology	2006
Brain cholesterol turnover required for geranylgeraniol production and learning in mice TJ Kotti, DM Ramirez, BE Pfeiffer, KM Huber, DW Russell	Proceedings of the National Academy of Sciences	2006
CREB4, a transmembrane bZip transcription factor and potential new substrate for regulation and cleavage by S1P J Stirling, P O'hare	Molecular biology of the cell	2006
SREBP Activation by Antipsychotic- and Antidepressant-Drugs in Cultured Human Liver Cells: Relevance for Metabolic Side-Effects? MB Raeder, J Fernø, AO Vik-Mo, VM Steen	Molecular and Cellular Biochemistry	2006
Cloning, comparative characterization of porcine SCAP gene, and identification of its two splice variants H Qiu, T Xia, X Chen, X Zhao, L Gan, S Feng, T Lei, Z Yang	Molecular Genetics and Genomics	2006
Clues to Neuro-Degeneration in Niemann-Pick Type C Disease from Global Gene Expression Profiling JV Reddy, IG Ganley, SR Pfeffer, W Hide	PloS one	2006
Key stages in mammary gland development - The alveolar switch: coordinating the proliferative cues and cell fate decisions that drive the formation of lobuloalveoli from ductal epithelium SR Oakes, HN Hilton, CJ Ormandy	Breast Cancer Research	2006
Investigation of de novo cholesterol synthetic capacity in the gonads of goldfish (Carassius auratus) exposed to the phytosterol beta-sitosterol RL Sharpe, M Drolet, DL MacLatchy	Reproductive Biology and Endocrinology	2006
Hepatic very-low-density lipoprotein and apolipoprotein B production are increased following in vivo induction of betaine–homocysteine S-methyltransferase JD Sparks, HL Collins, DV Chirieac, J Cianci, J Jokinen, MP Sowden, CA Galloway, CE Sparks	Biochemical Journal	2006
Combined Expression Trait Correlations and Expression Quantitative Trait Locus Mapping H Lan, M Chen, JB Flowers, BS Yandell, DS Stapleton, CM Mata, ET Mui, MT Flowers, KL Schueler, KF Manly, RW Williams, C Kendziorski, AD Attie, G Gibson	PLoS genetics	2006
Docosahexaneoic acid (22:6,n-3) regulates rat hepatocyte SREBP-1 nuclear abundance by Erk- and 26S proteasome-dependent pathways D Botolin, Y Wang, B Christian, DB Jump	Journal of lipid research	2006
Sources of Fatty Acids Stored in Liver and Secreted via Lipoproteins in Patients with Nonalcoholic Fatty Liver Disease Kerry Donnelly Peterson, Coleman I. Smith, Sarah J. Schwarzenberg, Jose Jessurun, Mark D. Boldt, Elizabeth J. Parks	Journal of Clinical Investigation	2005
Schoenheimer Effect explained - Feedback regulation of cholesterol synthesis in mice mediated by Insig proteins Luke J. Engelking, Guosheng Liang, Robert E. Hammer, Kiyosumi Takaishi, Hiroshi Kuriyama, Bret M. Evers, Wei-Ping Li, Jay D. Horton, Joseph L. Goldstein, and Michael S. Brown	Journal of Clinical Investigation	2005
Treatment of dyslipidemia in children and adolescents KW Holmes, PO Kwiterovich	Current Cardiology Reports	2005
Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids SB Kapadia, FV Chisari	Proceedings of the National Academy of Sciences	2005
Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9 S Rashid, DE Curtis, R Garuti, NN Anderson, Y Bashmakov, YK Ho, RE Hammer, YA Moon, JD Horton	Proceedings of the National Academy of Sciences	2005
Transcriptional regulation of lipid metabolism by fatty acids: a key determinant of pancreatic beta-cell function Z Fatehi-Hassanabad, CB Chan	Nutrition & Metabolism	2005
Distinct roles of insulin and liver X receptor in the induction and cleavage of sterol regulatory element-binding protein-1c BD Hegarty, A Bobard, I Hainault, P Ferré, P Bossard, F Foufelle	Proceedings of the National Academy of Sciences	2005
Hepatic farnesyl diphosphate synthase expression is suppressed by polyunsaturated fatty acids CL Jossic-Corcos, C Gonthier, I Zaghini, E Logette, I Shechter, P Bournot	Biochemical Journal	2005
A simple promoter containing two Sp1 sites controls the expression of sterol-regulatory-element-binding protein 1a (SREBP-1a) C Zhang, DJ Shin, TF Osborne	Biochemical Journal	2005
Caspase-2, a novel lipid sensor under the control of sterol regulatory element binding protein 2 E Logette, CL Jossic-Corcos, D Masson, S Solier, A Sequeira-Legrand, I Dugail, S Lemaire-Ewing, L Desoche, E Solary, L Corcos	Molecular and cellular biology	2005
Tissue-specific, nutritional, and developmental regulation of rat fatty acid elongases Y Wang, D Botolin, B Christian, J Busik, J Xu, DB Jump	Journal of lipid research	2005
Hyperphosphorylation regulates the activity of SREBP1 during mitosis MT Bengoechea-Alonso, T Punga, J Ericsson	Proceedings of the National Academy of Sciences	2005
Exploring hepatic hormone actions using a compilation of gene expression profiles N Ståhlberg, R Merino, LH Hernández, L Fernández-Pérez, A Sandelin, P Engström, P Tollet-Egnell, B Lenhard, A Flores-Morales	BMC Physiology	2005
Molecular characterization of HLH-17, a C. elegans bHLH protein required for normal larval development TL McMiller, CM Johnson	Gene	2005
Overexpression of Glucose-6-Phosphate Dehydrogenase Is Associated with Lipid Dysregulation and Insulin Resistance in Obesity J Park, HK Rho, KH Kim, SS Choe, YS Lee, JB Kim	Molecular and cellular biology	2005
Lipid Synthetic Transcription Factor SREBP-1a Activates p21 WAF1/CIP1 , a Universal Cyclin-Dependent Kinase Inhibitor N Inoue, H Shimano, M Nakakuki, T Matsuzaka, Y Nakagawa, T Yamamoto, R Sato, A Takahashi, H Sone, N Yahagi, H Suzuki, H Toyoshima, N Yamada	Molecular and cellular biology	2005
Spatial Distribution and Function of Sterol Regulatory Element-Binding Protein 1a and 2 Homo- and Heterodimers by In Vivo Two-Photon Imaging and Spectroscopy Fluorescence Resonance Energy Transfer A Zoumi, S Datta, LH Liaw, CJ Wu, G Manthripragada, TF Osborne, VJ LaMorte	Molecular and cellular biology	2005
Expression and regulation of sterol 27-hydroxylase (CYP27A1) in human macrophages: a role for RXR and PPARγ ligands CM QUINN, W JESSUP, J WONG, L KRITHARIDES, AJ BROWN	Biochemical Journal	2005
A role for PPARα in the control of SREBP activity and lipid synthesis in the liver BL Knight, A Hebbachi, D Hauton, AM Brown, D Wiggins, DD Patel, GF Gibbons	Biochemical Journal	2005
Nef Induces Multiple Genes Involved in Cholesterol Synthesis and Uptake in Human Immunodeficiency Virus Type 1-Infected T Cells AB van t Wout, JV Swain, M Schindler, U Rao, MS Pathmajeyan, JI Mullins, F Kirchhoff	Journal of virology	2005
Triglyceridemia and peroxisome proliferator-activated receptor-alpha expression are not connected in fenofibrate-treated pregnant rats. Soria A, González Mdel C, Vidal H, Herrera E, Bocos C	Molecular and Cellular Biochemistry	2005
Dysfunction of the cholesterol biosynthetic pathway in Huntington's disease. Valenza M, Rigamonti D, Goffredo D, Zuccato C, Fenu S, Jamot L, Strand A, Tarditi A, Woodman B, Racchi M, Mariotti C, Di Donato S, Corsini A, Bates G, Pruss R, Olson JM, Sipione S, Tartari M, Cattaneo E	The Journal of neuroscience : the official journal of the Society for Neuroscience	2005
Human low-density lipoprotein receptor gene and its regulation. Kong WJ, Liu J, Jiang JD	Journal of Molecular Medicine	2005
Overexpression of Insig-1 in livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis Luke J. Engelking, Hiroshi Kuriyama, Robert E. Hammer, Jay D. Horton, Michael S. Brown, Joseph L. Goldstein, Guosheng Liang	Journal of Clinical Investigation	2004
Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c Mitsuhiro Watanabe, Sander M. Houten, Li Wang, Antonio Moschetta, David J. Mangelsdorf, Richard A. Heyman, David D. Moore, Johan Auwerx	Journal of Clinical Investigation	2004
Disruption of cholesterol homeostasis by plant sterols Chengdong Yang, Liqing Yu, Weiping Li, Fang Xu, Jonathan C. Cohen, Helen H. Hobbs	Journal of Clinical Investigation	2004
GLUT4 glucose transporter deficiency increases hepatic lipid production and peripheral lipid utilization Ko Kotani, Odile D. Peroni1, Yasuhiko Minokoshi, Olivier Boss, Barbara B. Kahn	Journal of Clinical Investigation	2004
Peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha) regulates triglyceride metabolism by activation of the nuclear receptor FXR Y Zhang, LW Castellani, CJ Sinal, FJ Gonzalez, PA Edwards	Genes & development	2004
Disturbed cholesterol homeostasis in a peroxisome-deficient PEX2 knockout mouse model WJ Kovacs, JE Shackelford, KN Tape, MJ Richards, PL Faust, SJ Fliesler, SK Krisans	Molecular and cellular biology	2004
ATF6 modulates SREBP2-mediated lipogenesis L Zeng, M Lu, K Mori, S Luo, AS Lee, Y Zhu, JY Shyy	The EMBO Journal	2004
Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse K Ueki, T Kondo, YH Tseng, CR Kahn	Proceedings of the National Academy of Sciences	2004
The 3-hydroxy-3-methylglutaryl coenzyme-A (HMG-CoA) reductases JA Friesen, VW Rodwell	Genome biology	2004
Monomethyl branched-chain fatty acids play an essential role in Caenorhabditis elegans development M Kniazeva, QT Crawford, M Seiber, CY Wang, M Han	PLoS Biology	2004
Binding between the Niemann-Pick C1 protein and a photoactivatable cholesterol analog requires a functional sterol-sensing domain N Ohgami, DC Ko, M Thomas, MP Scott, CC Chang, TY Chang	Proceedings of the National Academy of Sciences	2004
Insig: a significant integrator of nutrient and hormonal signals AD Attie	Journal of Clinical Investigation	2004
Restoration of sterol-regulatory-element-binding protein-1c gene expression in HepG2 cells by peroxisome-proliferator-activated receptor-γ co-activator-1α H OBERKOFLER, E SCHRAML, F KREMPLER, W PATSCH	Biochemical Journal	2004
Novel Role for a Sterol Response Element Binding Protein in Directing Spermatogenic Cell-Specific Gene Expression H Wang, JT Agustin, GB Witman, DL Kilpatrick	Molecular and cellular biology	2004
Maintaining cholesterol homeostasis: sterol regulatory element-binding proteins. Weber LW, Boll M, Stampfl A	World Journal of Gastroenterology	2004
Modulation of 3-hydroxy-3-methylglutaryl-CoA reductase gene expression by CuZn superoxide dismutase in human fibroblasts and HepG2 cells. De Felice B, Santillo M, Serù R, Damiano S, Matrone G, Wilson RR, Mondola P	Gene expression	2004
Mechanisms of regulation of gene expression by fatty acids. Nakamura MT, Cheon Y, Li Y, Nara TY	Lipids	2004
Molecular mediators of hepatic steatosis and liver injury. Browning JD, Horton JD	Journal of Clinical Investigation	2004
Liver-specific disruption of the peroxisome proliferator receptor gamma in diabetic mice improves fatty liver, but aggravates hyperglycemia Kimihiko Matsusue, Martin Haluzik, Gilles Lambert, Sun-Hee Yim, Oksana Gavrilova, Jerrold M. Ward, Bryan Brewer, Marc L. Reitman, Frank J.Gonzalez	Journal of Clinical Investigation	2003
Keratinocyte growth factor and the transcription factors C/EBP alpha and delta and SREBP-1c regulate fatty acid synthesis in alveolar type II cells Robert J. Mason, Tianli Pan, Karen E. Edeedn, Larry D. Nielsen, Feijie Zhang, Malinda Longphre, Michael Eckart, and Steven Neben	Journal of Clinical Investigation	2003
Protein kinase Clambda in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity Michihiro Matsumoto, Wataru Ogawa, Kazunori Akimoto, Hiroshi Inoue, Kazuaki Miyake, Kensuke Furukawa, Yoshitake Hayashi, Haruhisa Iguchi, Yasushi Matsuki, Ryuji Hiramatsu, Hitoshi Shimano, Nobuhiro Yamada, Shigeo Ohno, Masato Kasuga & Tetsuo Noda	Journal of Clinical Investigation	2003
Advances in the Understanding and Treatment of Nonalcoholic Fatty Liver Disease: SA Harrison, AM Bisceglie	Drugs	2003
Occupancy and Function of the −150 Sterol Regulatory Element and −65 E-Box in Nutritional Regulation of the Fatty Acid Synthase Gene in Living Animals MJ Latasa, MJ Griffin, YS Moon, C Kang, HS Sul	Molecular and cellular biology	2003
Formation of 7-dehydrocholesterol-containing membrane rafts in vitro and in vivo, with relevance to the Smith-Lemli-Opitz syndrome RK Keller, TP Arnold, SJ Fliesler	Journal of lipid research	2003
Sustained peripheral expression of transgene adiponectin offsets the development of diet-induced obesity in rats S Shklyaev, G Aslanidi, M Tennant, V Prima, E Kohlbrenner, V Kroutov, M Campbell-Thompson, J Crawford, EW Shek, PJ Scarpace, S Zolotukhin	Proceedings of the National Academy of Sciences	2003
Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes JD Horton, NA Shah, JA Warrington, NN Anderson, SW Park, MS Brown, JL Goldstein	Proceedings of the National Academy of Sciences	2003
PPARdelta is a very low-density lipoprotein sensor in macrophages A Chawla, CH Lee, Y Barak, W He, J Rosenfeld, D Liao, J Han, H Kang, RM Evans	Proceedings of the National Academy of Sciences	2003
Liver-specific mRNA for Insig-2 down-regulated by insulin: implications for fatty acid synthesis D Yabe, R Komuro, G Liang, JL Goldstein, MS Brown	Proceedings of the National Academy of Sciences	2003
Twist2, a novel ADD1/SREBP1c interacting protein, represses the transcriptional activity of ADD1/SREBP1c YS Lee, HH Lee, J Park, EJ Yoo, CA Glackin, YI Choi, SH Jeon, RH Seong, SD Park, JB Kim	Nucleic Acids Research	2003
Local regulation of fat metabolism in peripheral nerves MH Verheijen, R Chrast, P Burrola, G Lemke	Genes & development	2003
Cholesterol-induced conformational change in SCAP enhanced by Insig proteins and mimicked by cationic amphiphiles CM Adams, JL Goldstein, MS Brown	Proceedings of the National Academy of Sciences	2003
Insig-1 "brakes" lipogenesis in adipocytes and inhibits differentiation of preadipocytes J Li, K Takaishi, W Cook, SK McCorkle, RH Unger	Proceedings of the National Academy of Sciences	2003
Trajectory clustering: a non-parametric method for grouping gene expression time courses, with applications to mammary development. Phang TL, Neville MC, Rudolph M, Hunter L	Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing	2003
Functional development of the mammary gland: use of expression profiling and trajectory clustering to reveal changes in gene expression during pregnancy, lactation, and involution. Rudolph MC, McManaman JL, Hunter L, Phang T, Neville MC	Journal of Mammary Gland Biology and Neoplasia	2003
Cholesterol in Health and Disease Ira Tabas	Journal of Clinical Investigation	2002
Malformation syndromes due to inborn errors of cholesterol synthesis Forbes Porter	Journal of Clinical Investigation	2002
Do oxysterols control cholesterol homeostasis? Ingemer Bjorkhem	Journal of Clinical Investigation	2002
Consequences of cellular cholesterol accumulation: basic concepts and physiological implications Ira Tabas	Journal of Clinical Investigation	2002
High-flux mitochondrial cholesterol trafficking, a specialized function of the adrenal gland Colin Jefcoat	Journal of Clinical Investigation	2002
Effects of SREBF-1a and SCAP polymorphisms on plasma levels of lipids, severity, progression and regression of coronary atherosclerosis and response to therapy with fluvastatin L Salek, S Lutucuta, CM Ballantyne, AM Gotto, AJ Marian	Journal of Molecular Medicine	2002
Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins D Yabe, MS Brown, JL Goldstein	Proceedings of the National Academy of Sciences	2002
Diversity, topographic differentiation, and positional memory in human fibroblasts HY Chang, JT Chi, S Dudoit, C Bondre, M de Rijn, D Botstein, PO Brown	Proceedings of the National Academy of Sciences	2002
From gallstones to genes: Two hundred years of sterol research. A tribute to George J. Schroepfer Jr GF Gibbons	Lipids	2002
The role of cytochrome P450 in the regulation of cholesterol biosynthesis. Gibbons GF	Lipids	2002
Regulation of the expression of the L-type pyruvate kinase gene in adult rat hepatocytes in primary culture G Chen, G Liang, J Ou, JL Goldstein, MS Brown	The Journal of biological chemistry	1989

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