Michael R. Knowles, Richard C. Boucher
Title and authors | Publication | Year |
---|---|---|
Mechanistic modelling of allergen-induced airways disease in early life
Pybus HJ, Dangarh P, Ng MY, Lloyd CM, Saglani S, Tanaka RJ |
Scientific Reports | 2025 |
Physiology and pathophysiology of mucus and mucolytic use in critically ill patients
Roe T, Talbot T, Terrington I, Johal J, Kemp I, Saeed K, Webb E, Cusack R, Grocott MP, Dushianthan A |
Critical Care | 2025 |
Advances in Oral Biomacromolecule Therapies for Metabolic Diseases
Jiao Q, Huang Y, He J, Xu Y |
Pharmaceutics | 2025 |
Intestinal mucus: the unsung hero in the battle against viral gastroenteritis
Saleem W, Aslam A, Tariq M, Nauwynck H |
Gut Pathogens | 2025 |
The physiological characteristics and applications of sialic acid
Wang B, Zhang T, Tang S, Liu C, Wang C, Bai J |
NPJ Science of Food | 2025 |
The Therapeutic Potential of Myo-Inositol in Managing Patients with Respiratory Diseases
Quecchia C, Vianello A |
International Journal of Molecular Sciences | 2025 |
The Oral Microbiome and Systemic Health: Bridging the Gap Between Dentistry and Medicine
Chandra Nayak S, Latha PB, Kandanattu B, Pympallil U, Kumar A, Kumar Banga H |
Cureus | 2025 |
Modulation of pulmonary immune functions by the Pseudomonas aeruginosa secondary metabolite pyocyanin
Lew SQ, Chong SY, Lau GW |
Frontiers in Immunology | 2025 |
Foreign Mucins Alter the Properties of Reconstituted Gastric Mucus
Henkel F, Lieleg O |
Biomacromolecules | 2025 |
Recent strategies for enhanced delivery of mRNA to the lungs
Heiser BJ, Veyssi A, Ghosh D |
Nanomedicine | 2025 |
The apical mucus layer alters the pharmacological properties of the airway epithelium
Guidone D, de Santis M, Pesce E, Capurro V, Pedemonte N, Galietta LJ |
The Journal of Physiology | 2025 |
Quantitative adverse outcome pathway modeling for cigarette-smoke-induced airway mucus hypersecretion. Part 1: adverse-outcome-pathway-based in vitro assessment with repeated exposure to whole cigarette smoke
Ichikawa S, Muratani S, Sano K, Erami K, Mori A, Matsumoto R, Ito S |
Frontiers in Toxicology | 2025 |
Mucus Structure, Viscoelastic Properties, and Composition in Chronic Respiratory Diseases
Abrami M, Biasin A, Tescione F, Tierno D, Dapas B, Carbone A, Grassi G, Conese M, Di Gioia S, Larobina D, Grassi M |
International journal of molecular sciences | 2024 |
Dual-color live imaging unveils stepwise organization of multiple basal body arrays by cytoskeletons.
Shiratsuchi G, Konishi S, Yano T, Yanagihashi Y, Nakayama S, Katsuno T, Kashihara H, Tanaka H, Tsukita K, Suzuki K, Herawati E, Watanabe H, Hirai T, Yagi T, Kondoh G, Gotoh S, Tamura A, Tsukita S |
EMBO reports | 2024 |
Animals in Respiratory Research.
Fröhlich E |
International journal of molecular sciences | 2024 |
Quercetin improves epithelial regeneration from airway basal cells of COPD patients.
McCluskey ES, Liu N, Pandey A, Marchetti N, Kelsen SG, Sajjan US |
Respiratory Research | 2024 |
scRNAseq analysis of primary ciliary dyskinesia airway reveals upregulation of a dedicated cilia glutathione pathway
Jeffrey Koenitzer, Deepesh Gupta, Wang Twan, Huihui Xu, Finn Hawkins, Mary Lou Beermann, Gervette M Penny, Nathan Wamsley, Andrew Berical, M Major, Susan Dutcher, Steven Brody, Amjad Horani |
JCI Insight | 2024 |
Inhaled "Muco-Trapping" Monoclonal Antibody Effectively Treats Established Respiratory Syncytial Virus (RSV) Infections.
McSweeney MD, Alnajjar S, Schaefer AM, Richardson Z, Wolf W, Stewart I, Sriboonyapirat P, McCallen J, Farmer E, Nzati B, Lord S, Farrer B, Moench TR, Kumar PA, Arora H, Pickles RJ, Hickey AJ, Ackermann M, Lai SK |
2024 | |
Microbiota and Immunity during Respiratory Infections: Lung and Gut Affair.
Marrella V, Nicchiotti F, Cassani B |
International journal of molecular sciences | 2024 |
Exploring the Correlation between Salivary Spinnbarkeit and Caries Scores.
Faruque MRJ, Taidouch K, Bikker FJ, Ligtenberg AJM |
Caries Research | 2024 |
How Does Airway Surface Liquid Composition Vary in Different Pulmonary Diseases, and How Can We Use This Knowledge to Model Microbial Infections?
Walsh D, Bevan J, Harrison F |
Microorganisms | 2024 |
Assessing susceptibility for polycyclic aromatic hydrocarbon toxicity in an in vitro 3D respiratory model for asthma
Valdez RM, Rivera BN, Chang Y, Pennington JM, Fischer KA, Löhr CV, Tilton SC |
2024 | |
In situ pulmonary mucus hydration assay using rotational and translational diffusion of gold nanorods with polarization-sensitive optical coherence tomography.
Oeler KJ, Blackmon RL, Kreda SM, Robinson T, Ghelardini M, Chapman BS, Tracy J, Hill DB, Oldenburg AL |
Journal of Biomedical Optics | 2024 |
Ezrin Contributes to the Damage of Airway Epithelial Barrier Related to Diabetes Mellitus.
Yu H, Luo C, Linghu R, Yang J, Wu H |
Journal of inflammation research | 2024 |
Impaired upper respiratory tract barrier function during postnatal development predisposes to invasive pneumococcal disease
Lokken-Toyli KL, Aggarwal SD, Bee GC, de Steenhuijsen Piters WA, Wu C, Chen KZ, Loomis C, Bogaert D, Weiser JN |
PLoS pathogens | 2024 |
Immune Response to Respiratory Viral Infections
Gambadauro A, Galletta F, Li Pomi A, Manti S, Piedimonte G |
International journal of molecular sciences | 2024 |
Mucus polymer concentration and in vivo adaptation converge to define the antibiotic response of Pseudomonas aeruginosa during chronic lung infection
Greenwald MA, Meinig SL, Plott LM, Roca C, Higgs MG, Vitko NP, Markovetz MR, Rouillard KR, Carpenter J, Kesimer M, Hill DB, Schisler JC, Wolfgang MC |
mBio | 2024 |
Bottlebrush Polyethylene Glycol Nanocarriers Translocate across Human Airway Epithelium via Molecular Architecture-Enhanced Endocytosis
He ZJ, Huang B, Cai LH |
ACS Nano | 2024 |
Aprotinin (II): Inhalational Administration for the Treatment of COVID-19 and Other Viral Conditions
Padín JF, Pérez-Ortiz JM, Redondo-Calvo FJ |
International journal of molecular sciences | 2024 |
Aprotinin (I): Understanding the Role of Host Proteases in COVID-19 and the Importance of Pharmacologically Regulating Their Function
Padín JF, Pérez-Ortiz JM, Redondo-Calvo FJ |
International journal of molecular sciences | 2024 |
Select amino acids recover cytokine-altered ENaC function in human bronchial epithelial cells.
Sasidharan A, Grosche A, Xu X, Kinane TB, Angoli D, Vidyasagar S |
PloS one | 2024 |
A gel-coated air-liquid-interface culture system with tunable substrate stiffness matching healthy and diseased lung tissues.
He ZJ, Chu C, Dickson R, Okuda K, Cai LH |
American journal of physiology. Lung cellular and molecular physiology | 2024 |
Cystic fibrosis.
Mall MA, Burgel PR, Castellani C, Davies JC, Salathe M, Taylor-Cousar JL |
Nature Reviews Disease Primers | 2024 |
The Interplay between Airway Cilia and Coronavirus Infection, Implications for Prevention and Control of Airway Viral Infections
Dai X, Xu R, Li N |
Cells | 2024 |
Dry Powder Inhaler Formulation of Lactobacillus rhamnosus GG Targeting Pseudomonas aeruginosa Infection in Bronchiectasis Maintenance Therapy
Tran TT, Cheow WS, Pu S, Park JW, Hadinoto K |
Pharmaceutics | 2024 |
Mucosal Penetrative Polymeric Micelle Formulations for Insulin Delivery to the Respiratory Tract
Kang JH, Jeong JH, Kwon YB, Kim YJ, Shin DH, Park YS, Hyun S, Kim DW, Park CW |
International Journal of Nanomedicine | 2024 |
Neutrophil serine proteases in cystic fibrosis: role in disease pathogenesis and rationale as a therapeutic target
Mall MA, Davies JC, Donaldson SH, Jain R, Chalmers JD, Shteinberg M |
European Respiratory Review | 2024 |
Bleomycin-Induced Pulmonary Fibrosis in Transgenic Mice Carrying the Human MUC5B rs35705950 Variant
Tharavecharak S, Fujimoto H, Yasuma T, D\u2019Alessandro-Gabazza CN, Toda M, Tomaru A, Saiki H, Uemura M, Kogue Y, Ito T, Furuhashi K, Okano T, Takeshita A, Nishihama K, Ono R, Hataji O, Nosaka T, Kobayashi T, Gabazza EC |
Cells | 2024 |
Modelling Mucus Clearance in Sinuses: Thin-Film Flow Inside a Fluid-Producing Cavity Lined with an Active Surface.
Desai N, Lauga E |
Bulletin of mathematical biology | 2024 |
Advances in studies on tracheal stent design addressing the related complications.
Chen S, Du T, Zhang H, Zhang Y, Qiao A |
Materials today. Bio | 2024 |
Live imaging of airway epithelium reveals that mucociliary clearance modulates SARS-CoV-2 spread.
Becker ME, Martin-Sancho L, Simons LM, McRaven MD, Chanda SK, Hultquist JF, Hope TJ |
Nature communications | 2024 |
Protective effect of interferon type I on barrier function of human airway epithelium during rhinovirus infections in vitro
Boland H, Endres A, Kinscherf R, Schubert R, Wilhelm B, Schwarzbach H, Jonigk D, Braubach P, Rohde G, Bellinghausen C |
Scientific Reports | 2024 |
Polymicrobial infection in cystic fibrosis and future perspectives for improving Mycobacterium abscessus drug discovery
Baker EJ, Allcott G, Cox JA |
npj Antimicrobials and Resistance | 2024 |
Characterization of a primary cellular airway model for inhalative drug delivery in comparison with the established permanent cell lines CaLu3 and RPMI 2650
Martin J, Rittersberger R, Treitler S, Kopp P, Ibraimi A, Koslowski G, Sickinger M, Dabbars A, Schindowski K |
In Vitro Models | 2024 |
Human coronaviruses: activation and antagonism of innate immune responses
Tanneti NS, Stillwell HA, Weiss SR |
Microbiology and Molecular Biology Reviews : MMBR | 2024 |
Opto-electromechanical quantification of epithelial barrier function in injured and healthy airway tissues
Chen J, Mir SM, Hudock MR, Pinezich MR, Chen P, Bacchetta M, Vunjak-Novakovic G, Kim J |
2023 | |
Characterization of Sialic Acid-Independent Simian Rotavirus Mutants in Viral Infection and Pathogenesis
Yamasaki M, Kanai Y, Wakamura Y, Kotaki T, Minami S, Nouda R, Nurdin JA, Kobayashi T |
Journal of virology | 2023 |
Airway mucus in pulmonary diseases: Muco-adhesive and muco-penetrating particles to overcome the airway mucus barriers
Pangeni R, Meng T, Poudel S, Sharma D, Hutsell H, Ma J, Rubin BK, Longest W, Hindle M, Xu Q |
International Journal of Pharmaceutics | 2023 |
Single-Cell RNA Sequencing Reveals New Basic and Translational Insights in the Cystic Fibrosis Lung.
Januska MN, Walsh MJ |
American journal of respiratory cell and molecular biology | 2023 |
Hyperoxia impairs intraflagellar transport and causes dysregulated metabolism with resultant decreased cilia length.
Teape D, Peterson A, Ahsan N, Ellis K, Correia N, Luo R, Hegarty K, Yao H, Dennery P |
American journal of physiology. Lung cellular and molecular physiology | 2023 |
Induction of systemic, mucosal, and cellular immunity against SARS‐CoV‐2 in mice vaccinated by trans‐airway with a S1 protein combined with a pulmonary surfactant‐derived adjuvant SF‐10
Kimoto T, Sakai S, Kameda K, Morita R, Takahashi E, Shinohara Y, Kido H |
Influenza and Other Respiratory Viruses | 2023 |
Motile cilia and microvillar: accomplices of SARS-CoV-2 in penetrating mucus barrier and infecting airway epithelium
Su P, Zhou F, Zhang L |
Signal Transduction and Targeted Therapy | 2023 |
Furin as a therapeutic target in cystic fibrosis airways disease.
Douglas LEJ, Reihill JA, Montgomery BM, Martin SL |
European respiratory review : an official journal of the European Respiratory Society | 2023 |
Basic Science Perspective on Engineering and Modeling the Large Airways.
Gautam LK, Harriott NC, Caceres AM, Ryan AL |
Advances in experimental medicine and biology | 2023 |
DNAH11 and a Novel Genetic Variant Associated with Situs Inversus: A Case Report and Review of the Literature.
Sodeifian F, Samieefar N, Shahkarami S, Rayzan E, Seyedpour S, Rohlfs M, Klein C, Babaie D, Rezaei N |
Case Reports in Medicine | 2023 |
Modulation of innate immunity in airway epithelium for host-directed therapy
Myszor IT, Gudmundsson GH |
Frontiers in immunology | 2023 |
Outer Membrane Vesicles (OMVs) as Biomedical Tools and Their Relevance as Immune-Modulating Agents against H. pylori Infections: Current Status and Future Prospects
Ahmed AA, Besio R, Xiao L, Forlino A |
International journal of molecular sciences | 2023 |
The Regulated Secretion and Models of Intracellular Transport: The Goblet Cell as an Example
Mironov AA, Beznoussenko GV |
International journal of molecular sciences | 2023 |
Macrophages Orchestrate Airway Inflammation, Remodeling, and Resolution in Asthma
Britt RD Jr, Ruwanpathirana A, Ford ML, Lewis BW |
International journal of molecular sciences | 2023 |
Endotracheal Tube Cleaning Devices: A Means But Not a Solution
Piccuito CM, Berra L |
Respiratory Care | 2023 |
Heterogeneous Damage to the Olfactory Epithelium in Patients with Post-Viral Olfactory Dysfunction
Kikuta S, Han B, Yamasoba T |
Journal of Clinical Medicine | 2023 |
Live imaging of the airway epithelium reveals that mucociliary clearance modulates SARS-CoV-2 spread
Hope T, Becker M, Martin-Sancho L, Simons L, McRaven M, Chanda S, Hultquist J |
Research square | 2023 |
The Dual Role of the Airway Epithelium in Asthma: Active Barrier and Regulator of Inflammation
Frey A, Lunding LP, Wegmann M |
Cells | 2023 |
Exploring intrinsic variability between cultured nasal and bronchial epithelia in cystic fibrosis.
Rodenburg LW, Metzemaekers M, van der Windt IS, Smits SMA, den Hertog-Oosterhoff LA, Kruisselbrink E, Brunsveld JE, Michel S, de Winter-de Groot KM, van der Ent CK, Stadhouders R, Beekman JM, Amatngalim GD |
Scientific Reports | 2023 |
COVID-19 Causes Ciliary Dysfunction as Demonstrated by Human Intranasal Micro-Optical Coherence Tomography Imaging
Vijaykumar K, Leung HM, Barrios A, Fernandez-Petty CM, Solomon GM, Hathorne HY, Wade JD, Monroe K, Slaten KB, Li Q, Leal SM Jr, Moates DB, Pierce HM, Olson KR, Currier P, Foster S, Marsden D, Tearney GJ, Rowe SM |
American journal of respiratory cell and molecular biology | 2023 |
A robust mRNA signature obtained via recursive ensemble feature selection predicts the responsiveness of omalizumab in moderate‐to‐severe asthma
Kidwai S, Barbiero P, Meijerman I, Tonda A, Perez\u2010Pardo P, Lio ´ P, van der Maitland\u2010Zee AH, Oberski DL, Kraneveld AD, Lopez\u2010Rincon A |
Clinical and Translational Allergy | 2023 |
SARS-CoV-2 particles promote airway epithelial differentiation and ciliation
Gonzalez-Rubio J, Le-Trilling VT, Baumann L, Cheremkhina M, Kubiza H, Luengen AE, Reuter S, Taube C, Ruetten S, Duarte Campos D, Cornelissen CG, Trilling M, Thiebes AL |
Frontiers in Bioengineering and Biotechnology | 2023 |
The role of cilia during organogenesis in zebrafish
Liu J, Xie H, Wu M, Hu Y, Kang Y |
Open Biology | 2023 |
Cilia‐related diseases
Ren Z, Mao X, Wang S, Wang X |
Journal of Cellular and Molecular Medicine | 2023 |
Computational Modeling Insights into Extreme Heterogeneity in COVID-19 Nasal Swab Data
Zhang L, Cao H, Medlin K, Pearson J, Aristotelous AC, Chen A, Wessler T, Forest MG |
Viruses | 2023 |
The power of weak, transient interactions across biology: A paradigm of emergent behavior
Vasquez PA, Walker B, Bloom K, Kolbin D, Caughman N, Freeman R, Lysy M, Hult C, Newhall KA, Papanikolas M, Edelmaier C, Forest MG |
Physica D. Nonlinear phenomena | 2023 |
Airway mucins promote immunopathology in virus-exacerbated chronic obstructive pulmonary disease
Aran Singanayagam, Joseph Footitt, Matthias Marczynski, Giorgia Radicioni, Michael Cross, Lydia J Finney, Maria-Belen Torralbo, Maria Adelaide Calderazzo, Jie Zhu, Julia Aniscenko, Thomas B Clarke, Philip L Molyneaux, Nathan W. Bartlett, Miriam Moffatt, William Cookson, Jadwiga A Wedzicha, Christopher M Evans, Richard Boucher, Mehmet Kesimer, Oliver Lieleg, Patrick Mallia, Sebastian L. Johnston |
Journal of Clinical Investigation | 2022 |
Commensal and Pathogenic Bacterial-Derived Extracellular Vesicles in Host-Bacterial and Interbacterial Dialogues: Two Sides of the Same Coin
S Tarashi, M Zamani, M Omrani, A Fateh, A Moshiri, A Saedisomeolia, S Siadat, S Kubow, A Torrecilhas |
Journal of Immunology Research | 2022 |
Nanoparticle Delivery Platforms for RNAi Therapeutics Targeting COVID-19 Disease in the Respiratory Tract
Y Zhang, J Almazi, H Ong, M Johansen, S Ledger, D Traini, P Hansbro, A Kelleher, C Ahlenstiel |
International journal of molecular sciences | 2022 |
Age-Related Differences in Structure and Function of Nasal Epithelial Cultures From Healthy Children and Elderly People
A Balázs, P Millar-Büchner, M Mülleder, V Farztdinov, L Szyrwiel, A Addante, A Kuppe, T Rubil, M Drescher, K Seidel, S Stricker, R Eils, I Lehmann, B Sawitzki, J Röhmel, M Ralser, M Mall |
Frontiers in immunology | 2022 |
Electronic cigarette vapor exposure exaggerates the pro-inflammatory response during influenza A viral infection in human distal airway epithelium
N Schaunaman, T Crue, D Cervantes, K Schweitzer, H Robbins, B Day, M Numata, I Petrache, H Chu |
Archives of Toxicology | 2022 |
Cell Membrane-Cloaked Nanotherapeutics for Targeted Drug Delivery.
Lee NH, You S, Taghizadeh A, Taghizadeh M, Kim HS |
International journal of molecular sciences | 2022 |
Effect of airway clearance therapies on mucociliary clearance in adults with cystic fibrosis: A randomized controlled trial.
Trimble A, Zeman K, Wu J, Ceppe A, Bennett W, Donaldson S |
PloS one | 2022 |
Involvement of the Innate Immune System in the Pathogenesis of Chronic Obstructive Pulmonary Disease
Kotlyarov S |
International journal of molecular sciences | 2022 |
Modeling insights into SARS-CoV-2 respiratory tract infections prior to immune protection.
Chen A, Wessler T, Daftari K, Hinton K, Boucher RC, Pickles R, Freeman R, Lai SK, Forest MG |
Biophysical Journal | 2022 |
Mucus Clearance Strategies in Mechanically Ventilated Patients.
Goetz RL, Vijaykumar K, Solomon GM |
Frontiers in physiology | 2022 |
A tethered ligand assay to probe SARS-CoV-2:ACE2 interactions
Bauer MS, Gruber S, Hausch A, Gomes PS, Milles LF, Nicolaus T, Schendel LC, Navajas PL, Procko E, Lietha D, Melo MC, Bernardi RC, Gaub HE, Lipfert J |
Proceedings of the National Academy of Sciences | 2022 |
CF Patients’ Airway Epithelium and Sex Contribute to Biosynthesis Defects of Pro-Resolving Lipids
Shum M, London CM, Briottet M, Sy KA, Baillif V, Philippe R, Zare A, Ghorbani-Dalini S, Remus N, Tarze A, Escabasse V, Epaud R, Dubourdeau M, Urbach V |
Frontiers in immunology | 2022 |
Prominin 1 and Notch regulate ciliary length and dynamics in multiciliated cells of the airway epithelium.
Serra CFH, Liu H, Qian J, Mori M, Lu J, Cardoso WV |
iScience | 2022 |
Taste Receptor Activation in Tracheal Brush Cells by Denatonium Modulates ENaC Channels via Ca2+, cAMP and ACh
Hollenhorst MI, Kumar P, Zimmer M, Salah A, Maxeiner S, Elhawy MI, Evers SB, Flockerzi V, Gudermann T, Chubanov V, Boehm U, Krasteva-Christ G |
Cells | 2022 |
An optimized protocol for assessment of sputum macrorheology in health and muco-obstructive lung disease
Völler M, Addante A, Rulff H, von Lospichl B, Gräber SY, Duerr J, Lauster D, Haag R, Gradzielski M, Mall MA |
Frontiers in physiology | 2022 |
Human Pulmonary Tuberculosis: Understanding the Immune Response in the Bronchoalveolar System
Herrera MT, Guzmán-Beltrán S, Bobadilla K, Santos-Mendoza T, Flores-Valdez MA, Gutiérrez-González LH, González Y |
Biomolecules | 2022 |
Pathogenesis of pneumonia and acute lung injury
Long ME, Mallampalli RK, Horowitz JC |
Clinical science (London, England : 1979) | 2022 |
The surface of airway epithelia exposed to IL-17/TNF-α switches between a hyperviscous and a fluid state under beta-adrenergic control
Daniela Guidone, Martina Buccirossi, Paolo Scudieri, Michele Genovese, Sergio Sarnataro, Rossella Cegli, Federico Cresta, Vito Terlizzi, Gabrielle Planelles, Gilles Crambert, Isabelle Sermet, Luis Galietta |
JCI Insight | 2022 |
The Novel Inducer of Innate Immunity HO53 Stimulates Autophagy in Human Airway Epithelial Cells
Myszor IT, Sigurdsson S, Viktorsdottir AR, Agerberth B, Eskelinen EL, Ogmundsdottir MH, Gudmundsson GH |
Journal of Innate Immunity | 2022 |
Radiographic Phenotypes Affect the Risk of Inhaled Corticosteroid-Associated Pneumonia in Patients with COPD
Lee HJ, Jin KN, Lee HW, Lee JK, Park TY, Heo EY, Kim DK |
International journal of chronic obstructive pulmonary disease | 2022 |
Intravital imaging of mucus transport in asthmatic mice using microscopic optical coherence tomography
Pieper M, Schulz-Hildebrandt H, Schmudde I, Quell KM, Laumonnier Y, Hüttmann G, König P |
AJP Lung Cellular and Molecular Physiology | 2022 |
Antibody protection from SARS-CoV-2 respiratory tract exposure and infection.
Chen A, Wessler T, Gregory Forest M |
Journal of Theoretical Biology | 2022 |
Negative cross-talk between TLR2/4-independent AMPKα1 and TLR2/4-dependent JNK regulates S. pneumoniae-induced mucosal innate immune response
Matsuyama S, Komatsu K, Lee BC, Tasaki Y, Miyata M, Xu H, Shuto T, Kai H, Li JD |
Journal of immunology (Baltimore, Md. : 1950) | 2022 |
Physiology and pathophysiology of human airway mucus
Hill DB, Button B, Rubinstein M, Boucher RC |
Physiological reviews | 2022 |
Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules
Hoang ON, Ermund A, Jaramillo AM, Fakih D, French CB, Flores JR, Karmouty-Quintana H, Magnusson JM, Fois G, Fauler M, Frick M, Braubach P, Hales JB, Kurten RC, Panettieri R, Vergara L, Ehre C, Adachi R, Tuvim MJ, Hansson GC, Dickey BF |
American journal of respiratory and critical care medicine | 2022 |
SARS-CoV-2 replication in airway epithelia requires motile cilia and microvillar reprogramming
Wu CT, Lidsky PV, Xiao Y, Cheng R, Lee IT, Nakayama T, Jiang S, He W, Demeter J, Knight MG, Turn RE, Rojas-Hernandez LS, Ye C, Chiem K, Shon J, Martinez-Sobrido L, Bertozzi CR, Nolan GP, Nayak JV, Milla C, Andino R, Jackson PK |
Cell | 2022 |
Impact of Elexacaftor-Tezacaftor-Ivacaftor on Bacterial Colonization and Inflammatory Responses in Cystic Fibrosis
Sheikh S, Britt RD Jr, Ryan-Wenger NA, Khan AQ, Lewis BW, Gushue C, Ozuna H, Jaganathan D, McCoy K, Kopp BT |
Pediatric Pulmonology | 2022 |
Autophagy of mucin granules contributes to resolution of airway mucous metaplasia
JM Sweeter, K Kudrna, K Hunt, P Thomes, BF Dickey, SL Brody, JD Dickinson |
Scientific Reports | 2021 |
Airway Surface Liquid pH Regulation in Airway Epithelium Current Understandings and Gaps in Knowledge
M Zajac, E Dreano, A Edwards, G Planelles, I Sermet-Gaudelus |
International journal of molecular sciences | 2021 |
Mucociliary Respiratory Epithelium Integrity in Molecular Defense and Susceptibility to Pulmonary Viral Infections
Adivitiya, MS Kaushik, S Chakraborty, S Veleri, S Kateriya |
Biology : open access journal | 2021 |
Immune Responses to Pseudomonas aeruginosa Biofilm Infections
C Moser, PØ Jensen, K Thomsen, M Kolpen, M Rybtke, AS Lauland, H Trøstrup, T Tolker-Nielsen |
Frontiers in immunology | 2021 |
Early Diagnosis and Intervention in Cystic Fibrosis: Imagining the Unimaginable
AM Coverstone, TW Ferkol |
Frontiers in Pediatrics | 2021 |
New Therapies to Correct the Cystic Fibrosis Basic Defect
C Bergeron, AM Cantin |
International journal of molecular sciences | 2021 |
Mechanisms of Post-Pancreatitis Diabetes Mellitus and Cystic Fibrosis-Related Diabetes: A Review of Preclinical Studies
E Gál, J Dolenšek, A Stožer, L Czakó, A Ébert, V Venglovecz |
Frontiers in Endocrinology | 2021 |
Glycated Albumin Triggers an Inflammatory Response in the Human Airway Epithelium and Causes an Increase in Ciliary Beat Frequency
ML Aitken, R Somayaji, TR Hinds, M Pier, K Droguett, M Rios, SJ Skerrett, M Villalon |
Frontiers in physiology | 2021 |
Modeling Airway Dysfunction in Asthma Using Synthetic Mucus Biomaterials
D Song, E Iverson, L Kaler, S Bader, MA Scull, GA Duncan |
ACS Biomaterials Science & Engineering | 2021 |
Induction of ciliary orientation by matrix patterning and characterization of mucociliary transport
PR Sears, XM Bustamante-Marin, H Gong, MR Markovetz, R Superfine, DB Hill, LE Ostrowski |
Biophysical Journal | 2021 |
Cystic Fibrosis Lung Disease Modifiers and Their Relevance in the New Era of Precision Medicine
A Sepahzad, DJ Morris-Rosendahl, JC Davies |
Genes & development | 2021 |
Safety Evaluation of Nanotechnology Products
AJ Domb, G Sharifzadeh, V Nahum, H Hosseinkhani |
Pharmaceutics | 2021 |
The role of Psl in the failure to eradicate Pseudomonas aeruginosa biofilms in children with cystic fibrosis
AJ Morris, L Jackson, YC Yau, C Reichhardt, T Beaudoin, S Uwumarenogie, KM Guttman, PL Howell, MR Parsek, LR Hoffman, D Nguyen, A DiGiandomenico, DS Guttman, DJ Wozniak, VJ Waters |
npj Biofilms and Microbiomes | 2021 |
Mukoziliäre Clearance bei COVID-19-Erkrankungen: Ein unterschätztes Gefahrengebiet in der Frühphase?
T Wittig |
MMW - Fortschritte der Medizin | 2021 |
Hyperinflammation and airway surface liquid dehydration in cystic fibrosis: purinergic system as therapeutic target
TI do Carmo, VE Soares, J Wruck, F dos Anjos, DT de Resende e Silva, SF de Oliveira Maciel, MD Bagatini |
Inflammation Research | 2021 |
Airway Basal Cells, Protectors of Epithelial Walls in Health and Respiratory Diseases
E Ruysseveldt, K Martens, B Steelant |
2021 | |
Proteases, Mucus, and Mucosal Immunity in Chronic Lung Disease
MC McKelvey, R Brown, S Ryan, MA Mall, S Weldon, CC Taggart |
International journal of molecular sciences | 2021 |
Molecular dynamics simulations to explore the structure and rheological properties of normal and hyperconcentrated airway mucus
A Ford, X Cao, M Papanikolas, T Kato, R Boucher, M Markovetz, D Hill, R Freeman, M Forest |
Studies in Applied Mathematics | 2021 |
Major Determinants of Airway Epithelial Cell Sensitivity to S. aureus Alpha-Toxin: Disposal of Toxin Heptamers by Extracellular Vesicle Formation and Lysosomal Degradation
N Möller, S Ziesemer, C Hentschker, U Völker, JP Hildebrandt |
Toxins | 2021 |
An Adverse Outcome Pathway for Decreased Lung Function Focusing on Mechanisms of Impaired Mucociliary Clearance Following Inhalation Exposure
K Luettich, M Sharma, H Yepiskoposyan, D Breheny, F Lowe |
2021 | |
The MUC5B Promoter Polymorphism Associates With Severe COVID-19 in the European Population
CH van Moorsel, JJ van der Vis, A Duckworth, CJ Scotton, C Benschop, D Ellinghaus, HJ Ruven, MJ Quanjel, JC Grutters |
Frontiers in Medicine | 2021 |
Entropy Production in Electroosmotic Cilia Facilitated Stream of Thermally Radiated Nanofluid with Ohmic Heating.
Saleem N, Munawar S, Mehmood A, Daqqa I |
Micromachines | 2021 |
Airway Epithelial Innate Immunity.
Johnston SL, Goldblatt DL, Evans SE, Tuvim MJ, Dickey BF |
Frontiers in physiology | 2021 |
Defining the Clinical Utility of the Lung Clearance Index. Are We There Yet?
Spano J, Milla CE |
American journal of respiratory and critical care medicine | 2021 |
Lung Microbiome in Cystic Fibrosis.
Scialo F, Amato F, Cernera G, Gelzo M, Zarrilli F, Comegna M, Pastore L, Bianco A, Castaldo G |
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Potential of helper-dependent Adenoviral vectors in CRISPR-cas9-mediated lung gene therapy.
Bandara RA, Chen ZR, Hu J |
Cell & Bioscience | 2021 |
The Betacoronavirus PHEV Replicates and Disrupts the Respiratory Epithelia and Upregulates Key Pattern Recognition Receptor Genes and Downstream Mediators, Including IL-8 and IFN-λ.
Nelli RK, Mora-Díaz JC, Giménez-Lirola LG |
mSphere | 2021 |
OCT particle tracking velocimetry of biofluids in a microparallel plate strain induction chamber
Oeler KJ, Hill DB, Oldenburg AL |
Journal of Biomedical Optics | 2021 |
Entropy generation in thermally radiated hybrid nanofluid through an electroosmotic pump with ohmic heating: Case of synthetic cilia regulated stream
Munawar S, Saleem N |
Science Progress | 2021 |
Lack of airway submucosal glands impairs respiratory host defenses
LS Ostedgaard, MP Price, KM Whitworth, MH Alaiwa, AJ Fischer, A Warrier, M Samuel, LD Spate, PD Allen, BM Hilkin, GS Ibarra, ME Bezara, BJ Goodell, SE Mather, LS Powers, MR Stroik, ND Gansemer, CE Hippee, K Zarei, JA Goeken, TR Businga, EA Hoffman, DK Meyerholz, RS Prather, DA Stoltz, MJ Welsh |
eLife | 2020 |
Ionocytes and CFTR Chloride Channel Expression in Normal and Cystic Fibrosis Nasal and Bronchial Epithelial Cells
P Scudieri, I Musante, A Venturini, D Guidone, M Genovese, F Cresta, E Caci, A Palleschi, M Poeta, F Santamaria, F Ciciriello, V Lucidi, LJ Galietta |
Cells | 2020 |
Acid exposure disrupts mucus secretion and impairs mucociliary transport in neonatal piglet airways
YS Liao, SP Kuan, MV Guevara, EN Collins, KR Atanasova, JS Dadural, K Vogt, V Schurmann, L Bravo, E Eken, M Sponchiado, LR Reznikov |
American journal of physiology. Lung cellular and molecular physiology | 2020 |
Epithelial cell function and remodeling in nasal polyposis
LG Bankova, NA Barrett |
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology | 2020 |
The Innate Lymphoid System Is a Critical Player in the Manifestation of Mucoinflammatory Airway Disease in Mice
BW Lewis, I Choudhary, K Paudel, Y Mao, R Sharma, Y Wang, JS Deshane, RC Boucher, S Patial, Y Saini |
Journal of immunology (Baltimore, Md. : 1950) | 2020 |
S. aureus alpha-toxin monomer binding and heptamer formation in host cell membranes – Do they determine sensitivity of airway epithelial cells toward the toxin?
N Möller, S Ziesemer, P Hildebrandt, N Assenheimer, U Völker, JP Hildebrandt, L Bulla |
PloS one | 2020 |
Airway mechanical compression: its role in asthma pathogenesis and progression
PC Veerati, JA Mitchel, AT Reid, DA Knight, NW Bartlett, JA Park, CL Grainge |
European Respiratory Review | 2020 |
The Role of Specialized Pro-Resolving Mediators in Cystic Fibrosis Airways Disease
M Briottet, M Shum, V Urbach |
Frontiers in pharmacology | 2020 |
ENaC inhibition in cystic fibrosis: potential role in the new era of CFTR modulator therapies
MA Mall |
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology | 2020 |
Ablation of IL-33 Suppresses Th2 Responses but Is Accompanied by Sustained Mucus Obstruction in the Scnn1b Transgenic Mouse Model
BW Lewis, T Vo, I Choudhary, A Kidder, C Bathula, C Ehre, N Wakamatsu, S Patial, Y Saini |
Journal of immunology (Baltimore, Md. : 1950) | 2020 |
Preclinical evaluation of the epithelial sodium channel inhibitor BI 1265162 for treatment of cystic fibrosis
P Nickolaus, B Jung, J Sabater, S Constant, A Gupta |
ERJ Open Research | 2020 |
A mathematical model describing the localization and spread of influenza A virus infection within the human respiratory tract
C Quirouette, NP Younis, MB Reddy, CA Beauchemin, R Antia |
PLoS computational biology | 2020 |
TRPV4: A Physio and Pathophysiologically Significant Ion Channel
T Rosenbaum, M Benítez-Angeles, R Sánchez-Hernández, SL Morales-Lázaro, M Hiriart, LE Morales-Buenrostro, F Torres-Quiroz |
International journal of molecular sciences | 2020 |
Mechanisms of Epithelial Immunity Evasion by Respiratory Bacterial Pathogens
L Sharma, J Feng, CJ Britto, CS Cruz |
Frontiers in immunology | 2020 |
Apolipoprotein E and Periostin Are Potential Biomarkers of Nasal Mucosal Inflammation. A Parallel Approach of In Vitro and In Vivo Secretomes
YW Chung, J Cha, S Han, Y Chen, M Gucek, HJ Cho, K Nakahira, AM Choi, JH Ryu, JH Yoon |
American journal of respiratory cell and molecular biology | 2020 |
Rhinovirus and Innate Immune Function of Airway Epithelium
H Ganjian, C Rajput, M Elzoheiry, U Sajjan |
Frontiers in Cellular and Infection Microbiology | 2020 |
Intravital microscopic optical coherence tomography imaging to assess mucus-mobilizing interventions for muco-obstructive lung disease in mice
M Pieper, H Schulz-Hildebrandt, MA Mall, G Hüttmann, P König |
American journal of physiology. Lung cellular and molecular physiology | 2020 |
Nicotine stimulates ion transport via metabotropic β4 subunit containing nicotinic ACh receptors
P Kumar, P Scholze, M Fronius, G KrastevaChrist, MI Hollenhorst |
British Journal of Pharmacology | 2020 |
Zwitterionic micelles efficiently deliver oral insulin without opening tight junctions
X Han, Y Lu, J Xie, E Zhang, H Zhu, H Du, K Wang, B Song, C Yang, Y Shi, Z Cao |
Nature Nanotechnology | 2020 |
Airway cholinergic history modifies mucus secretion properties to subsequent cholinergic challenge in diminished chloride and bicarbonate conditions
YS Liao, EN Collins, MV Guevara, V Schurmann, KR Atanasova, L Bravo, M Sponchiado, MJ Hoegger, LR Reznikov |
Experimental Physiology | 2020 |
Mucins and the Microbiome
GC Hansson |
Annual Review of Biochemistry | 2020 |
Ammonia Exposure Induced Cilia Dysfunction of Nasal Mucosa in the Piglets.
Wang Q, Wang M, Liu C, Huang L, Gao Y, Yu M, Zhao S, Li X |
BioMed Research International | 2020 |
S-allylmercaptocysteine inhibits mucin overexpression and inflammation via MAPKs and PI3K-Akt signaling pathways in acute respiratory distress syndrome.
An L, Zhao J, Sun X, Zhou Y, Zhao Z |
Pharmacological Research | 2020 |
Bioinspired cilia arrays with programmable nonreciprocal motion and metachronal coordination.
Dong X, Lum GZ, Hu W, Zhang R, Ren Z, Onck PR, Sitti M |
Science Advances | 2020 |
The versatile X-ray beamline of the Munich Compact Light Source: design, instrumentation and applications.
Günther B, Gradl R, Jud C, Eggl E, Huang J, Kulpe S, Achterhold K, Gleich B, Dierolf M, Pfeiffer F |
Journal of Synchrotron Radiation | 2020 |
A comparative study of the turnover of multiciliated cells in the mouse trachea, oviduct, and brain.
Roberson EC, Tran NK, Konjikusic MJ, Fitch RD, Gray RS, Wallingford JB |
Developmental dynamics : an official publication of the American Association of Anatomists | 2020 |
Invited review: human air-liquid-interface organotypic airway tissue models derived from primary tracheobronchial epithelial cells-overview and perspectives.
Cao X, Coyle JP, Xiong R, Wang Y, Heflich RH, Ren B, Gwinn WM, Hayden P, Rojanasakul L |
In vitro cellular & developmental biology. Animal | 2020 |
In Vitro and In Vivo Assessment of PEGylated PEI for Anti-IL-8/CxCL-1 siRNA Delivery to the Lungs
Hibbitts AJ, Ramsey JM, Barlow J, MacLoughlin R, Cryan SA |
Nanomaterials | 2020 |
Treatment of Cystic Fibrosis Patients Homozygous for F508del with Lumacaftor-Ivacaftor (Orkambi®) Restores Defective CFTR Channel Function in Circulating Mononuclear Cells.
Favia M, Gallo C, Guerra L, De Venuto D, Diana A, Polizzi AM, Montemurro P, Mariggiò MA, Leonetti G, Manca A, Casavola V, Conese M |
International journal of molecular sciences | 2020 |
Engineered mutant α-ENaC subunit mRNA delivered by lipid nanoparticles reduces amiloride currents in cystic fibrosis-based cell and mice models.
Mukherjee A, MacDonald KD, Kim J, Henderson MI, Eygeris Y, Sahay G |
Science Advances | 2020 |
Modified Sialic Acids on Mucus and Erythrocytes Inhibit Influenza A Virus Hemagglutinin and Neuraminidase Functions
Barnard KN, Alford-Lawrence BK, Buchholz DW, Wasik BR, LaClair JR, Yu H, Honce R, Ruhl S, Pajic P, Daugherity EK, Chen X, Schultz-Cherry SL, Aguilar HC, Varki A, Parrish CR |
Journal of virology | 2020 |
Paracellular Pathway-Mediated Mycoplasma hyopneumoniae Migration across Porcine Airway Epithelial Barrier under Air-Liquid Interface Conditions
Wang H, Zhang Z, Xie X, Liu B, Wei Y, Gan Y, Yuan T, Ni B, Wang J, Zhang L, Xiong Q, Shao G, Feng Z |
Infection and immunity | 2020 |
Evaluation of nasal mucociliary clearance time in patients with Vitamin-D deficiency
FA Akcan, Y Dündar, HB Akcan, A Uluat, D Cebeci, İ Ünlü |
European Archives of Oto-Rhino-Laryngology | 2019 |
TMEM16A in Cystic Fibrosis: Activating or Inhibiting?
K Kunzelmann, J Ousingsawat, I Cabrita, T Doušová, A Bähr, M Janda, R Schreiber, R Benedetto |
Frontiers in pharmacology | 2019 |
Upregulation of the WNK4 Signaling Pathway Inhibits Epithelial Sodium Channels of Mouse Tracheal Epithelial Cells After Influenza A Infection
Y Hou, Y Cui, Z Zhou, H Liu, H Zhang, Y Ding, H Nie, HL Ji |
Frontiers in pharmacology | 2019 |
Targeted Gene Delivery through the Respiratory System: Rationale for Intratracheal Gene Transfer
M Katz, A Fargnoli, S Gubara, K Fish, T Weber, C Bridges, R Hajjar, K Ishikawa |
Journal of Cardiovascular Development and Disease | 2019 |
Sphingomyelin Depletion from Plasma Membranes of Human Airway Epithelial Cells Completely Abrogates the Deleterious Actions of S. aureus Alpha-Toxin
S Ziesemer, N Möller, A Nitsch, C Müller, A Beule, JP Hildebrandt |
Toxins | 2019 |
Roles of Cyclic AMP Response Element Binding Activation in the ERK1/2 and p38 MAPK Signalling Pathway in Central Nervous System, Cardiovascular System, Osteoclast Differentiation and Mucin and Cytokine Production
Y Koga, H Tsurumaki, H Aoki-Saito, M Sato, M Yatomi, K Takehara, T Hisada |
International journal of molecular sciences | 2019 |
Inflammation and Endotyping in Chronic Rhinosinusitis—A Paradigm Shift
S Ahern, A Cervin |
MED LITH | 2019 |
Novel aroylated phenylenediamine compounds enhance antimicrobial defense and maintain airway epithelial barrier integrity
IT Myszor, Z Parveen, H Ottosson, P Bergman, B Agerberth, R Strömberg, GH Gudmundsson |
Scientific Reports | 2019 |
Immunopathology of Airway Surface Liquid Dehydration Disease
BW Lewis, S Patial, Y Saini |
Journal of Immunology Research | 2019 |
Airway regeneration using iPS cell-derived airway epithelial cells with Cl - channel function
S Yoshie, K Omori, A Hazama |
Channels (Austin, Tex.) | 2019 |
Mechanical shear controls bacterial penetration in mucus
N Figueroa-Morales, L Dominguez-Rubio, TL Ott, IS Aranson |
Scientific Reports | 2019 |
Particle coating alters mucociliary transit in excised rat trachea: A synchrotron X-ray imaging study
M Gardner, A McCarron, K Morgan, D Parsons, M Donnelley |
Scientific Reports | 2019 |
Stenotrophomonas maltophilia Differential Gene Expression in Synthetic Cystic Fibrosis Sputum Reveals Shared and Cystic Fibrosis Strain-Specific Responses to the Sputum Environment
GG Willsey, K Eckstrom, AE LaBauve, LA Hinkel, K Schutz, RJ Meagher, JJ LiPuma, MJ Wargo, MY Galperin |
Journal of bacteriology | 2019 |
Nebulized hypertonic saline in noncystic fibrosis bronchiectasis: a comprehensive review
LM Carro, MA Martínez-García |
Therapeutic advances in respiratory disease | 2019 |
Mathematical Modeling of Mucociliary Clearance: A Mini-Review
L Xu, Y Jiang |
Cells | 2019 |
Mucin Thin Layers: A Model for Mucus-Covered Tissues
Rondelli, Cola, Koutsioubas, Alongi, Ferruti, Ranucci, Brocca |
International journal of molecular sciences | 2019 |
Inhaled Biologicals for the Treatment of Cystic Fibrosis
V Sala, A Murabito, A Ghigo |
Recent Patents on Inflammation & Allergy Drug Discovery | 2019 |
The Cancer Microbiota: EMT and Inflammation as Shared Molecular Mechanisms Associated with Plasticity and Progression
D Vergara, P Simeone, M Damato, M Maffia, P Lanuti, M Trerotola |
Journal of Oncology | 2019 |
Nanoparticle diffusion in spontaneously expectorated sputum as a biophysical tool to probe disease severity in COPD
JF Chisholm, SK Shenoy, JK Shade, V Kim, N Putcha, KA Carson, R Wise, NN Hansel, JS Hanes, JS Suk, E Neptune |
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology | 2019 |
Spatial Mapping of Tracheal Ciliary Beat Frequency Using Real Time Phase-Resolved Doppler Spectrally Encoded Interferometric Microscopy
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ACS Photonics | 2019 |
Engineering Polymer-Binding Bispecific Antibodies for Enhanced Pretargeted Delivery of Nanoparticles to Mucus-Covered Epithelium.
Huckaby JT, Parker CL, Jacobs TM, Schaefer A, Wadsworth D, Nguyen A, Wang A, Newby J, Lai SK |
Angewandte Chemie (International ed. in English) | 2019 |
Comparing the Performance Characteristics of Different Positive Expiratory Pressure Devices.
Franks LJ, Walsh JR, Hall K, Jacuinde G, Yerkovich S, Morris NR |
Respiratory Care | 2019 |
Cystic Fibrosis Lung Disease: An Overview.
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Respiratory Care | 2019 |
ATP12A promotes mucus dysfunction during Type 2 airway inflammation
AT Lennox, SL Coburn, JA Leech, EM Heidrich, TR Kleyman, SE Wenzel, JM Pilewski, TE Corcoran, MM Myerburg |
Scientific Reports | 2018 |
Fatty Acid Metabolism is Associated With Disease Severity After H7N9 Infection
X Sun, L Song, S Feng, L Li, H Yu, Q Wang, X Wang, Z Hou, X Li, Y Li, Q Zhang, K Li, C Cui, J Wu, Z Qin, Q Wu, H Chen |
EBioMedicine | 2018 |
Buffer drains and mucus is transported upward in a tilted mucus clearance assay
J Carpenter, SE Lynch, JA Cribb, S Kylstra, DB Hill, R Superfine |
American journal of physiology. Lung cellular and molecular physiology | 2018 |
Mucus models to evaluate the diffusion of drugs and particles
JY Lock, TL Carlson, RL Carrier |
Advanced Drug Delivery Reviews | 2018 |
Seeing cilia: imaging modalities for ciliary motion and clinical connections
JE Peabody, RJ Shei, BM Bermingham, SE Phillips, B Turner, SM Rowe, GM Solomon |
American journal of physiology. Lung cellular and molecular physiology | 2018 |
Mucin Production and Hydration Responses to Mucopurulent Materials in Normal versus Cystic Fibrosis Airway Epithelia
LH Abdullah, R Coakley, MJ Webster, Y Zhu, R Tarran, G Radicioni, M Kesimer, RC Boucher, CW Davis, CM Ribeiro |
American journal of respiratory and critical care medicine | 2018 |
New insights into the mechanisms controlling the bronchial mucus balance
C Karamaoun, B Sobac, B Mauroy, AV Muylem, B Haut, N Palaniyar |
PloS one | 2018 |
Airway disease phenotypes in animal models of cystic fibrosis
A McCarron, M Donnelley, D Parsons |
Respiratory Research | 2018 |
Taste receptors in the upper airway
JR Freund, RJ Lee |
World Journal of Otorhinolaryngology-Head and Neck Surgery | 2018 |
Role of mucins in lung homeostasis: regulated expression and biosynthesis in health and disease
BA Symmes, AL Stefanski, CM Magin, CM Evans |
Biochemical Society Transactions | 2018 |
Secondhand Smoke Induces Inflammation and Impairs Immunity to Respiratory Infections
TA Bhat, SG Kalathil, PN Bogner, A Miller, PV Lehmann, TH Thatcher, RP Phipps, PJ Sime, Y Thanavala |
Journal of immunology (Baltimore, Md. : 1950) | 2018 |
Recent advances in developing therapeutics for cystic fibrosis
LJ Strug, AL Stephenson, N Panjwani, A Harris |
Human Molecular Genetics | 2018 |
An Adeno-Associated Viral Vector Capable of Penetrating the Mucus Barrier to Inhaled Gene Therapy
GA Duncan, N Kim, Y Colon-Cortes, J Rodriguez, M Mazur, SE Birket, SM Rowe, NE West, A Livraghi-Butrico, RC Boucher, J Hanes, G Aslanidi, JS Suk |
Molecular Therapy — Methods & Clinical Development | 2018 |
ZMapp Reinforces the Airway Mucosal Barrier Against Ebola Virus
B Yang, A Schaefer, YY Wang, J McCallen, P Lee, JM Newby, H Arora, PA Kumar, L Zeitlin, KJ Whaley, SA McKinley, WA Fischer, D Harit, SK Lai |
The Journal of Infectious Diseases | 2018 |
Transport and Mixing Induced by Beating Cilia in Human Airways
S Chateau, U D'Ortona, S Poncet, J Favier |
Frontiers in physiology | 2018 |
Rhinosectan® spray (containing xyloglucan) on the ciliary function of the nasal respiratory epithelium; results of an in vitro study
N Piqué, BD Servi |
Allergy Asthma & Clinical Immunology | 2018 |
In vivo Dynamic Phase-Contrast X-ray Imaging using a Compact Light Source
R Gradl, M Dierolf, B Günther, L Hehn, W Möller, D Kutschke, L Yang, M Donnelley, R Murrie, A Erl, T Stoeger, B Gleich, K Achterhold, O Schmid, F Pfeiffer, KS Morgan |
Scientific Reports | 2018 |
Spatiotemporal organization of cilia drives multiscale mucus swirls in model human bronchial epithelium
MK Khelloufi, E Loiseau, M Jaeger, N Molinari, P Chanez, D Gras, A Viallat |
Scientific Reports | 2018 |
Bordetella pseudohinzii targets cilia and impairs tracheal cilia-driven transport in naturally acquired infection in mice
A Perniss, N Schmidt, C Gurtner, K Dietert, O Schwengers, M Weigel, J Hempe, C Ewers, U Pfeil, U Gärtner, AD Gruber, T Hain, W Kummer |
Scientific Reports | 2018 |
Pathophysiology and Genetics of Bronchiectasis Unrelated to Cystic Fibrosis
A Nikolic |
Lung | 2018 |
Airway Epithelial Cell Function and Respiratory Host Defense in Chronic Obstructive Pulmonary Disease
GD Amatngalim, PS Hiemstra |
Chinese Medical Journal | 2018 |
Technological strategies to estimate and control diffusive passage times through the mucus barrier in mucosal drug delivery
JM Newby, I Seim, M Lysy, Y Ling, J Huckaby, SK Lai, MG Forest |
Advanced Drug Delivery Reviews | 2018 |
Predictors of pneumonia on routine chest radiographs in patients with COPD: a post hoc analysis of two 1-year randomized controlled trials
DB Rubin, HA Ahmad, M O'Neal, S Bennett, S Lettis, DV Galkin, C Crim |
International journal of chronic obstructive pulmonary disease | 2018 |
Molecular strategy for blocking isopeptide bond formation in nascent pilin proteins
JA Rivas-Pardo, CL Badilla, R Tapia-Rojo, Á Alonso-Caballero, JM Fernández |
Proceedings of the National Academy of Sciences | 2018 |
Mucociliary Clearance in Mice Measured by Tracking Trans-tracheal Fluorescence of Nasally Aerosolized Beads
TD Rogers, LE Ostrowski, A Livraghi-Butrico, B Button, BR Grubb |
Scientific Reports | 2018 |
Temporal differentiation of bovine airway epithelial cells grown at an air-liquid interface
D Cozens, E Sutherland, F Marchesi, G Taylor, CC Berry, RL Davies |
Scientific Reports | 2018 |
Functional Anatomic Imaging of the Airway Surface
RJ Shei, JE Peabody, SM Rowe |
Annals of the American Thoracic Society | 2018 |
Chair’s Summary: Secreted Mucins in Lung Diseases
BF Dickey |
Annals of the American Thoracic Society | 2018 |
Ivacaftor improves rhinologic, psychologic, and sleep-related quality of life in G551D cystic fibrosis patients: Improved quality of life in G551D CF patients
J McCormick, DY Cho, B Lampkin, J Richman, H Hathorne, SM Rowe, BA Woodworth |
International Forum of Allergy & Rhinology | 2018 |
Tissue-dependent expression of bitter receptor TAS2R38 mRNA
JE Douglas, C Lin, CJ Mansfield, CJ Arayata, BJ Cowart, AI Spielman, ND Adappa, JN Palmer, NA Cohen, DR Reed |
Chemical Senses | 2018 |
The development and functions of multiciliated epithelia
N Spassky, A Meunier |
Nature Reviews Molecular Cell Biology | 2017 |
Ex vivo visualization of human ciliated epithelium and quantitative analysis of induced flow dynamics by using optical coherence tomography: EX VIVO VISUALIZATION OF HUMAN CILIATED EPITHELIUM
Y Ling, X Yao, UA Gamm, E Arteaga-Solis, CW Emala, MA Choma, CP Hendon |
Lasers in Surgery and Medicine | 2017 |
Taste Receptors Mediate Sinonasal Immunity and Respiratory Disease
J Douglas, N Cohen |
International journal of molecular sciences | 2017 |
Lyn regulates mucus secretion and MUC5AC via the STAT6 signaling pathway during allergic airway inflammation
X Wang, Y Li, D Luo, X Wang, Y Zhang, Z Liu, N Zhong, M Wu, G Li |
Scientific Reports | 2017 |
Air Pollution and Climate Change Effects on Allergies in the Anthropocene: Abundance, Interaction, and Modification of Allergens and Adjuvants
K Reinmuth-Selzle, CJ Kampf, K Lucas, N Lang-Yona, J Fröhlich-Nowoisky, M Shiraiwa, PS Lakey, S Lai, F Liu, AT Kunert, K Ziegler, F Shen, R Sgarbanti, B Weber, I Bellinghausen, J Saloga, MG Weller, A Duschl, D Schuppan, U Pöschl |
Environmental science & technology | 2017 |
Quantitative Proteomic Analysis of Human Airway Cilia Identifies Previously Uncharacterized Proteins of High Abundance
K Blackburn, X Bustamante-Marin, W Yin, MB Goshe, LE Ostrowski |
Journal of Proteome Research | 2017 |
Curcumin Inhibits NTHi-Induced MUC5AC Mucin Overproduction in Otitis Media via Upregulation of MAPK Phosphatase MKP-1
AS Konduru, S Matsuyama, BC Lee, K Komatsu, JD Li |
International Journal of Inflammation | 2017 |
Lung structure and function similarities between primary ciliary dyskinesia and mild cystic fibrosis: a pilot study
M Maglione, S Montella, C Mollica, V Carnovale, P Iacotucci, FD Gregorio, A Tosco, M Cervasio, V Raia, F Santamaria |
Italian Journal of Pediatrics | 2017 |
Flavones modulate respiratory epithelial innate immunity: Anti-inflammatory effects and activation of the T2R14 receptor
BM Hariri, DB McMahon, B Chen, JR Freund, CJ Mansfield, LJ Doghramji, ND Adappa, JN Palmer, DW Kennedy, DR Reed, P Jiang, RJ Lee |
The Journal of biological chemistry | 2017 |
Active microrheology determines scale-dependent material properties of Chaetopterus mucus
WJ Weigand, A Messmore, J Tu, A Morales-Sanz, DL Blair, DD Deheyn, JS Urbach, RM Robertson-Anderson, K Garikipati |
PloS one | 2017 |
The particle in the spider's web: transport through biological hydrogels
J Witten, K Ribbeck |
Nanoscale | 2017 |
Small Airway Absorption and Microdosimetry of Inhaled Corticosteroid Particles after Deposition
PW Longest, M Hindle |
Pharmaceutical Research | 2017 |
Ets homologous factor (EHF) has critical roles in epithelial dysfunction in airway disease
SL Fossum, MJ Mutolo, A Tugores, S Ghosh, SH Randell, LC Jones, SH Leir, A Harris |
The Journal of biological chemistry | 2017 |
A new index for characterizing micro-bead motion in a flow induced by ciliary beating: Part II, modeling
M Bottier, MP Fernández, G Pelle, D Isabey, B Louis, JB Grotberg, M Filoche, M Alber |
PLoS computational biology | 2017 |
A new index for characterizing micro-bead motion in a flow induced by ciliary beating: Part I, experimental analysis
M Bottier, S Blanchon, G Pelle, E Bequignon, D Isabey, A Coste, E Escudier, JB Grotberg, JF Papon, M Filoche, B Louis, M Alber |
PLoS computational biology | 2017 |
Overnight delivery of hypertonic saline by nasal cannula aerosol for cystic fibrosis
TE Corcoran, JE Godovchik, KH Donn, DR Busick, J Goralski, LW Locke, MR Markovetz, MM Myerburg, A Muthukrishnan, L Weber, RT Lacy, JM Pilewski |
Pediatric Pulmonology | 2017 |
Cystic fibrosis swine fail to secrete airway surface liquid in response to inhalation of pathogens
X Luan, G Belev, JS Tam, S Jagadeeshan, N Hassan, P Gioino, N Grishchenko, Y Huang, JL Carmalt, T Duke, T Jones, B Monson, M Burmester, T Simovich, O Yilmaz, VA Campanucci, TE Machen, LD Chapman, JP Ianowski |
Nature Communications | 2017 |
Physicochemical properties of mucus and their impact on transmucosal drug delivery
J Leal, HD Smyth, D Ghosh |
International Journal of Pharmaceutics | 2017 |
Mitochondrial toxicity of tobacco smoke and air pollution
JL Fetterman, MJ Sammy, SW Ballinger |
Toxicology | 2017 |
SPX-101 Is a Promising and Novel Nebulized ENaC Inhibitor
A Lennox, MM Myerburg |
American journal of respiratory and critical care medicine | 2017 |
Role of Smad3 and p38 Signalling in Cigarette Smoke-induced CFTR and BK dysfunction in Primary Human Bronchial Airway Epithelial Cells
J Sailland, A Grosche, N Baumlin, JS Dennis, A Schmid, S Krick, M Salathe |
Scientific Reports | 2017 |
Motile cilia create fluid-mechanical microhabitats for the active recruitment of the host microbiome
JC Nawroth, H Guo, E Koch, EA Heath-Heckman, JC Hermanson, EG Ruby, JO Dabiri, E Kanso, M McFall-Ngai |
Proceedings of the National Academy of Sciences | 2017 |
Efficacy of Rhesus Theta-Defensin-1 in Experimental Models of Pseudomonas aeruginosa Lung Infection and Inflammation
TJ Bensman, JG Jayne, M Sun, E Kimura, J Meinert, JC Wang, JB Schaal, D Tran, AP Rao, O Akbari, ME Selsted, PM Beringer |
Antimicrobial agents and chemotherapy | 2017 |
Enhancement of lung gene delivery after aerosol: a new strategy using non-viral complexes with antibacterial properties
A Mottais, T Le Gall, Y Sibiril, J Ravel, V Laurent, F dArbonneau, T Montier |
Bioscience Reports | 2017 |
Impaired PGE2-stimulated Cl- and HCO3- secretion contributes to cystic fibrosis airway disease
ZM Sellers, B Illek, MF Figueira, G Hari, NS Joo, E Sibley, J Souza-Menezes, MM Morales, H Fischer, JJ Wine, S Ahmad |
PloS one | 2017 |
In Vitro Models to Study Human Lung Development, Disease and Homeostasis
AJ Miller, JR Spence |
Physiology (Bethesda, Md.) | 2017 |
Epithelial tethering of MUC5AC-rich mucus impairs mucociliary transport in asthma
Luke Bonser, Lorna Zlock, Walter Finkbeiner, David J. Erle |
Journal of Clinical Investigation | 2016 |
Repurposing Tromethamine as Inhaled Therapy to Treat CF Airway Disease
Mahmoud Abou Alaiwa, Janice Launspach, Kelsey Sheets, Jade Rivera, Nicholas Gansemer, Peter Taft, Peter Thorne, Michael Welsh, David Stoltz, Joseph Zabner |
JCI Insight | 2016 |
Microstructural Alterations of Sputum in Cystic Fibrosis Lung Disease
Gregg Duncan, James Jung, Andrea Joseph, Abigail Thaxton, Natalie West, Michael Boyle, Justin Hanes, Jung Soo Suk |
JCI Insight | 2016 |
Longer latency of sensory response to intravenous odor injection predicts olfactory neural disorder
S Kikuta, Y Matsumoto, A Kuboki, T Nakayama, D Asaka, N Otori, H Kojima, T Sakamoto, K Akinori, K Kanaya, R Ueha, R Kagoya, H Nishijima, M Toma-Hirano, Y Kikkawa, K Kondo, K Tsunoda, T Miyaji, T Yamaguchi, K Kataoka, K Mori, T Yamasoba |
Scientific Reports | 2016 |
Goblet Cell Hyperplasia Requires High Bicarbonate Transport To Support Mucin Release
G Gorrieri, P Scudieri, E Caci, M Schiavon, V Tomati, F Sirci, F Napolitano, D Carrella, A Gianotti, I Musante, M Favia, V Casavola, L Guerra, F Rea, R Ravazzolo, DD Bernardo, LJ Galietta |
Scientific Reports | 2016 |
Effect of TH2 cytokines and interferon gamma on beat frequency of human respiratory cilia
J Grosse-Onnebrink, C Werner, NT Loges, K Hörmann, A Blum, R Schmidt, H Olbrich, H Omran |
Pediatric Research | 2016 |
Non-diluted seawater enhances nasal ciliary beat frequency and wound repair speed compared to diluted seawater and normal saline: Seawater superior to saline on CBF and WRS
A Bonnomet, E Luczka, C Coraux, L Gabory |
International Forum of Allergy & Rhinology | 2016 |
The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Uses its C-Terminus to Regulate the A2B Adenosine Receptor
MJ Watson, SL Lee, AJ Marklew, RC Gilmore, M Gentzsch, MF Sassano, MA Gray, R Tarran |
Scientific Reports | 2016 |
Inhibition of airway surface fluid absorption by cholinergic stimulation
NS Joo, ME Krouse, JY Choi, HJ Cho, JJ Wine |
Scientific Reports | 2016 |
The evolving spectrum of ciliopathies and respiratory disease:
CE Milla |
Current Opinion in Pediatrics | 2016 |
Airway bacteria drive a progressive COPD-like phenotype in mice with polymeric immunoglobulin receptor deficiency
BW Richmond, RM Brucker, W Han, RH Du, Y Zhang, DS Cheng, L Gleaves, R Abdolrasulnia, D Polosukhina, PE Clark, SR Bordenstein, TS Blackwell, VV Polosukhin |
Nature Communications | 2016 |
Aerosol Delivery of siRNA to the Lungs. Part 1: Rationale for Gene Delivery Systems
SR Youngren-Ortiz, NS Gandhi, L España-Serrano, MB Chougule |
KONA POWDER PART J | 2016 |
Taste Receptors: Regulators of Sinonasal Innate Immunity: Taste Receptors
RM Carey, ND Adappa, JN Palmer, RJ Lee, NA Cohen |
Laryngoscope Investigative Otolaryngology | 2016 |
The genetics of the bitter taste receptor T2R38 in upper airway innate immunity and implications for chronic rhinosinusitis: T2R38 Genetics and Chronic Rhinosinusitis
NA Cohen |
The Laryngoscope | 2016 |
A Macroscopic Model for Simulating the Mucociliary Clearance in a Bronchial Bifurcation: The Role of Surface Tension
M Manolidis, D Isabey, B Louis, JB Grotberg, M Filoche |
Journal of Biomechanical Engineering | 2016 |
Cilia and Mucociliary Clearance
XM Bustamante-Marin, LE Ostrowski |
Cold Spring Harbor perspectives in biology | 2016 |
ATS Core Curriculum 2016: Part III. Pediatric Pulmonary Medicine
D Boyer, CC Thomson, R Cohen, D Rao, S Dell, J Rayment, R Wang, FJ Dy, J Wambach, J Tam-Williams, D Simon, E Price, CM Oermann, A Singh, JS Rettig, ED Duncan, CD Baker, DR Liptzin, PE Moore |
Annals of the American Thoracic Society | 2016 |
Pneumonia
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Pathology of Lung Disease | 2016 |
Cilia Dysfunction in Lung Disease
AE Tilley, MS Walters, R Shaykhiev, RG Crystal |
Annual Review of Physiology | 2015 |
Cystic fibrosis
F Ratjen, SC Bell, SM Rowe, CH Goss, AL Quittner, A Bush |
Nature Reviews Disease Primers | 2015 |
Airway hydration and COPD
A Ghosh, RC Boucher, R Tarran |
Cellular and Molecular Life Sciences | 2015 |
Pediatric Cystic Fibrosis Sputum Can Be Chemically Dynamic, Anoxic, and Extremely Reduced Due to Hydrogen Sulfide Formation
ES Cowley, SH Kopf, A LaRiviere, W Ziebis, DK Newman |
mBio | 2015 |
Ferret and Pig Models of Cystic Fibrosis: Prospects and Promise for Gene Therapy
Z Yan, ZA Stewart, PL Sinn, JC Olsen, J Hu, PB McCray, JF Engelhardt |
Human Gene Therapy Clinical Development | 2015 |
Genetics, diagnosis and future treatment strategies for primary ciliary dyskinesia
ML Daniels, PG Noone |
Expert Opinion on Orphan Drugs | 2015 |
Proteomic Analysis of Pure Human Airway Gland Mucus Reveals a Large Component of Protective Proteins
NS Joo, IA Evans, HJ Cho, IH Park, JF Engelhardt, JJ Wine, JM Jacobs |
PloS one | 2015 |
Successful Treatment Of Chronic Lower Respiratory Tract Infection By Macrolide Administration In A Patient With Intralobar Pulmonary Sequestration And Primary Ciliary Dyskinesia
H Tsubouchi, N Matsumoto, S Yanagi, J Ashitani, M Nakazato |
Respiratory Medicine Case Reports | 2015 |
The lung communication network
D Losa, M Chanson |
Cellular and Molecular Life Sciences | 2015 |
Evaluation of nasal mucociliary activity in patients with chronic renal failure
C Kucur, I Ozbay, E Gulcan, S Kulekci, S Aksoy, F Oghan |
European Archives of Oto-Rhino-Laryngology | 2015 |
1,8-Cineol Reduces Mucus-Production in a Novel Human Ex Vivo Model of Late Rhinosinusitis
H Sudhoff, C Klenke, JF Greiner, J Müller, V Brotzmann, J Ebmeyer, B Kaltschmidt, C Kaltschmidt, YP Di |
PloS one | 2015 |
Airway Surface Dehydration Aggravates Cigarette Smoke-Induced Hallmarks of COPD in Mice
LJ Seys, FM Verhamme, LL Dupont, E Desauter, J Duerr, AS Agircan, G Conickx, GF Joos, GG Brusselle, MA Mall, KR Bracke, M Idzko |
PloS one | 2015 |
Continuous mucociliary transport by primary human airway epithelial cells in vitro
PR Sears, WN Yin, LE Ostrowski |
American journal of physiology. Lung cellular and molecular physiology | 2015 |
Vinpocetine Inhibits Streptococcus pneumoniae-Induced Upregulation of Mucin MUC5AC Expression via Induction of MKP-1 Phosphatase in the Pathogenesis of Otitis Media
JY Lee, K Komatsu, BC Lee, M Miyata, AO Bohn, H Xu, C Yan, JD Li |
Journal of immunology (Baltimore, Md. : 1950) | 2015 |
The Src-Family Kinases Hck and Fgr Regulate Early Lipopolysaccharide-Induced Myeloid Cell Recruitment into the Lung and Their Ability To Secrete Chemokines
P Mazzi, E Caveggion, JA Lapinet-Vera, CA Lowell, G Berton |
Journal of immunology (Baltimore, Md. : 1950) | 2015 |
Salt, chloride, bleach, and innate host defense
G Wang, WM Nauseef |
Journal of leukocyte biology | 2015 |
The Evolution of Cystic Fibrosis Care
JE Pittman, TW Ferkol |
Chest | 2015 |
Impact of Cardiopulmonary Bypass on Respiratory Mucociliary Function in an Experimental Porcine Model
R Sánchez-Véliz, MJ Carmona, DA Otsuki, C Freitas, A Benício, EM Negri, LM Malbouisson, F Staffieri |
PloS one | 2015 |
The expansion of autologous adipose-derived stem cells in vitro for the functional reconstruction of nasal mucosal tissue
X Xu, L Li, C Wang, Y Liu, C Chen, J Yan, H Ding, S Tang |
Cell & Bioscience | 2015 |
Cryptococcus neoformans Infection in Mice Lacking Type I Interferon Signaling Leads to Increased Fungal Clearance and IL-4-Dependent Mucin Production in the Lungs
K Sato, H Yamamoto, T Nomura, I Matsumoto, T Miyasaka, T Zong, E Kanno, K Uno, K Ishii, K Kawakami, EA Eugenin |
PloS one | 2015 |
The Role of Bitter and Sweet Taste Receptors in Upper Airway Immunity
AD Workman, JN Palmer, ND Adappa, NA Cohen |
Current Allergy and Asthma Reports | 2015 |
Chronic rhinosinusitis pathogenesis
WW Stevens, RJ Lee, RP Schleimer, NA Cohen |
Journal of Allergy and Clinical Immunology | 2015 |
Nanoparticle based insulin delivery system: the next generation efficient therapy for Type 1 diabetes
G Sharma, AR Sharma, JS Nam, GP Doss, SS Lee, C Chakraborty |
Journal of nanobiotechnology | 2015 |
Nasal Mucociliary Clearance in Adenoid Hypertrophy and Otitis Media with Effusion
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Current Allergy and Asthma Reports | 2015 |
A role for airway taste receptor modulation in the treatment of upper respiratory infections
JE Douglas, CJ Saunders, DR Reed, NA Cohen |
Expert Review of Respiratory Medicine | 2015 |
Putting the Squeeze on Airway Epithelia
JA Park, JJ Fredberg, JM Drazen |
Physiology (Bethesda, Md.) | 2015 |
Defective Innate Immunity and Hyperinflammation in Newborn Cystic Fibrosis Transmembrane Conductance Regulator–Knockout Ferret Lungs
NW Keiser, SE Birket, IA Evans, SR Tyler, AK Crooke, X Sun, W Zhou, JR Nellis, EK Stroebele, KK Chu, GJ Tearney, MJ Stevens, JK Harris, SM Rowe, JF Engelhardt |
American journal of respiratory cell and molecular biology | 2014 |
Mammalian short palate lung and nasal epithelial clone 1 (SPLUNC1) in pH-dependent airway hydration
R Tarran, MR Redinbo |
The International Journal of Biochemistry & Cell Biology | 2014 |
Nitrous Oxide Production in Sputum from Cystic Fibrosis Patients with Chronic Pseudomonas aeruginosa Lung Infection
M Kolpen, M Kühl, T Bjarnsholt, C Moser, CR Hansen, L Liengaard, A Kharazmi, T Pressler, N Høiby, PØ Jensen, E Gulbins |
PloS one | 2014 |
Vocal Fold Ion Transport and Mucin Expression Following Acrolein Exposure
EE Levendoski, MP Sivasankar |
The Journal of Membrane Biology | 2014 |
Cystic fibrosis: An inherited disease affecting mucin-producing organs
C Ehre, C Ridley, DJ Thornton |
The International Journal of Biochemistry & Cell Biology | 2014 |
Cystic Fibrosis: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases
JE Pittman, G Cutting, SD Davis, T Ferkol, R Boucher |
Annals of the American Thoracic Society | 2014 |
dsRNA-induced changes in gene expression profiles of primary nasal and bronchial epithelial cells from patients with asthma, rhinitis and controls
AH Wagener, AH Zwinderman, S Luiten, WJ Fokkens, EH Bel, PJ Sterk, CM van Drunen |
Respiratory Research | 2014 |
Proteome of the porosome complex in human airway epithelia: Interaction with the cystic fibrosis transmembrane conductance regulator (CFTR)
X Hou, KT Lewis, Q Wu, S Wang, X Chen, A Flack, G Mao, DJ Taatjes, F Sun, BP Jena |
Journal of Proteomics | 2014 |
A pilot study of an in-vitro bovine trachea model of the effect of continuous positive airway pressure breathing on airway surface liquid
DE White, RJ Nates, J Bartley |
BioMedical Engineering OnLine | 2014 |
Effect of cigarette smoking on nasal mucociliary clearance: A comparative analysis using saccharin test
MK Baby, PK Muthu, P Johnson, S Kannan |
Lung India : official organ of Indian Chest Society | 2014 |
Pseudomonas aeruginosa triggers CFTR-mediated airway surface liquid secretion in swine trachea
X Luan, VA Campanucci, M Nair, O Yilmaz, G Belev, TE Machen, D Chapman, JP Ianowski |
Proceedings of the National Academy of Sciences | 2014 |
Nanoparticle penetration of human cervicovaginal mucus: The effect of polyvinyl alcohol
M Yang, SK Lai, T Yu, YY Wang, C Happe, W Zhong, M Zhang, A Anonuevo, C Fridley, A Hung, J Fu, J Hanes |
Journal of Controlled Release | 2014 |
Gaining the Upper Hand on Pulmonary Drug Delivery
J Tyrrell, R Tarran |
2014 | |
Basal foot MTOC organizes pillar MTs required for coordination of beating cilia
DK Clare, J Magescas, T Piolot, M Dumoux, C Vesque, E Pichard, T Dang, B Duvauchelle, F Poirier, D Delacour |
Nature Communications | 2014 |
Taste receptors in innate immunity
RJ Lee, NA Cohen |
Cellular and Molecular Life Sciences | 2014 |
Ets homologous factor regulates pathways controlling response to injury in airway epithelial cells
SL Fossum, MJ Mutolo, R Yang, H Dang, WK O'Neal, MR Knowles, SH Leir, A Harris |
Nucleic Acids Research | 2014 |
Endogenous lung surfactant inspired pH responsive nanovesicle aerosols: Pulmonary compatible and site-specific drug delivery in lung metastases
N Joshi, N Shirsath, A Singh, KS Joshi, R Banerjee |
Scientific Reports | 2014 |
Allergic Airway Inflammation Decreases Lung Bacterial Burden following Acute Klebsiella pneumoniae Infection in a Neutrophil- and CCL8-Dependent Manner
DE Dulek, DC Newcomb, K Goleniewska, J Cephus, W Zhou, S Reiss, S Toki, F Ye, R Zaynagetdinov, TP Sherrill, TS Blackwell, ML Moore, KL Boyd, JK Kolls, RS Peebles |
Infection and immunity | 2014 |
Linking increased airway hydration, ciliary beating, and mucociliary clearance through ENaC inhibition
AB Astrand, M Hemmerling, J Root, C Wingren, J Pesic, E Johansson, AL Garland, A Ghosh, R Tarran |
American journal of physiology. Lung cellular and molecular physiology | 2014 |
Mycoplasma pneumoniae Modulates STAT3-STAT6/EGFR-FOXA2 Signaling To Induce Overexpression of Airway Mucins
Y Hao, Z Kuang, J Jing, J Miao, LY Mei, RJ Lee, S Kim, S Choe, DC Krause, GW Lau |
Infection and immunity | 2014 |
IL-1 induction of MUC5AC gene expression is mediated by CREB and NF- B and repressed by dexamethasone
Y Chen, LM Garvin, TJ Nickola, AM Watson, AM Colberg-Poley, MC Rose |
American journal of physiology. Lung cellular and molecular physiology | 2014 |
Vocal Fold Epithelial Barrier in Health and Injury: A Research Review
EE Levendoski, C Leydon, SL Thibeault |
Journal of speech, language, and hearing research : JSLHR | 2014 |
Porosome in Cystic Fibrosis
BP Jena |
Discoveries | 2014 |
Tumor Necrosis Factor Alpha Induces a Serotonin Dependent Early Increase in Ciliary Beat Frequency and Epithelial Transport Velocity in Murine Tracheae
S Weiterer, D Schulte, S Müller, T Kohlen, F Uhle, MA Weigand, M Henrich, H Fehrenbach |
PloS one | 2014 |
Challenges associated with Penetration of Nanoparticles across Cell and Tissue Barriers: A Review of Current Status and Future Prospects
Barua S, Mitragotri S |
Nano Today | 2014 |
Quantifying the effects of altering ambient humidity on ionic composition of vocal fold surface fluid
MP Sivasankar, TL Carroll, AM Kosinski, CA Rosen |
The Laryngoscope | 2013 |
Liquid hyper-absorption as a cause of increased DTPA clearance in the cystic fibrosis airway
TE Corcoran, KM Thomas, S Brown, MM Myerburg, LW Locke, JM Pilewski |
EJNMMI Research | 2013 |
Intrapulmonary Versus Nasal Transduction of Murine Airways With GP64-pseudotyped Viral Vectors
M Oakland, W Maury, PB McCray, PL Sinn |
Molecular Therapy — Nucleic Acids | 2013 |
Repression of the Equilibrative Nucleoside Transporters Dampens Inflammatory Lung Injury
JC Morote-Garcia, D Köhler, JM Roth, V Mirakaj, T Eldh, HK Eltzschig, P Rosenberger |
American journal of respiratory cell and molecular biology | 2013 |
Comprehensive Physiology
A Tsuda, FS Henry, JP Butler |
Comprehensive Physiology | 2013 |
Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways
AL Garland, WG Walton, RD Coakley, CD Tan, RC Gilmore, CA Hobbs, A Tripathy, LA Clunes, S Bencharit, MJ Stutts, L Betts, MR Redinbo, R Tarran |
Proceedings of the National Academy of Sciences | 2013 |
Barrier function of airway tract epithelium
S Ganesan, AT Comstock, US Sajjan |
Tissue Barriers | 2013 |
Primary Ciliary Dyskinesia. Recent Advances in Diagnostics, Genetics, and Characterization of Clinical Disease
MR Knowles, LA Daniels, SD Davis, MA Zariwala, MW Leigh |
American journal of respiratory and critical care medicine | 2013 |
Influenza A penetrates host mucus by cleaving sialic acids with neuraminidase
M Cohen, XQ Zhang, HP Senaati, HW Chen, NM Varki, RT Schooley, P Gagneux |
Virology Journal | 2013 |
The impact of topically applied preservation solutions on the respiratory epithelium of tracheal grafts submitted to cold ischemia: functional and morphological analysis
AE de Azevedo-Pereira, JA Saka, KA de Oliveira-Braga, R Pazetti, M Canzian, PM Pêgo-Fernandes, FB Jatene |
Clinics (São Paulo, Brazil) | 2013 |
Abnormal nasal nitric oxide production, ciliary beat frequency, and Toll-like receptor response in pulmonary nontuberculous mycobacterial disease epithelium
CJ Fowler, KN Olivier, JM Leung, CC Smith, AG Huth, H Root, DB Kuhns, C Logun, A Zelazny, CA Frein, J Daub, C Haney, JH Shelhamer, CE Bryant, SM Holland |
American journal of respiratory and critical care medicine | 2013 |
Control of Airway Tube Diameter and Integrity by Secreted Chitin-Binding Proteins in Drosophila
K Tiklová, V Tsarouhas, C Samakovlis, EM Skoulakis |
PloS one | 2013 |
Postentry Processing of Recombinant Adeno-Associated Virus Type 1 and Transduction of the Ferret Lung Are Altered by a Factor in Airway Secretions
Z Yan, X Sun, IA Evans, SR Tyler, Y Song, X Liu, H Sui, JF Engelhardt |
Human Gene Therapy | 2013 |
Continuum-kinetic-microscopic model of lung clearance due to core-annular fluid entrainment
S Mitran |
Journal of Computational Physics | 2013 |
Mucociliary Clearance Defects in a Murine In Vitro Model of Pneumococcal Airway Infection
M Fliegauf, AF Sonnen, B Kremer, P Henneke, S Jeyaseelan |
PloS one | 2013 |
Primary ciliary dyskinesia-causing mutations in Amish and Mennonite communities
TW Ferkol, EG Puffenberger, H Lie, C Helms, KA Strauss, A Bowcock, JL Carson, M Hazucha, DH Morton, AC Patel, MW Leigh, MR Knowles, MA Zariwala |
The Journal of Pediatrics | 2013 |
Status of Fluid and Electrolyte Absorption in Cystic Fibrosis
MM Reddy, MJ Stutts |
Cold Spring Harbor Perspectives in Medicine | 2013 |
A novel approach to quantifying ciliary physiology: microfluidic mixing driven by a ciliated biological surface
S Jonas, E Zhou, E Deniz, B Huang, K Chandrasekera, D Bhattacharya, Y Wu, R Fan, TM Deserno, MK Khokha, MA Choma |
Lab on a Chip | 2013 |
Identification of the SPLUNC1 ENaC-inhibitory domain yields novel strategies to treat sodium hyperabsorption in cystic fibrosis airway epithelial cultures
CA Hobbs, MG Blanchard, O Alijevic, CD Tan, S Kellenberger, S Bencharit, R Cao, M Kesimer, WG Walton, AG Henderson, MR Redinbo, MJ Stutts, R Tarran |
American journal of physiology. Lung cellular and molecular physiology | 2013 |
Increased Susceptibility to Pulmonary Pseudomonas Infection in Splunc1 Knockout Mice
Y Liu, ME Di, HW Chu, X Liu, L Wang, S Wenzel, YP Di |
Journal of immunology (Baltimore, Md. : 1950) | 2013 |
Use of Single-Site-Functionalized PEG Dendrons To Prepare Gene Vectors that Penetrate Human Mucus Barriers
AJ Kim, NJ Boylan, JS Suk, M Hwangbo, T Yu, BS Schuster, L Cebotaru, WG Lesniak, JS Oh, P Adstamongkonkul, AY Choi, RM Kannan, J Hanes |
Angewandte Chemie | 2013 |
Cystic Fibrosis Chronic Rhinosinusitis: A Comprehensive Review
MR Chaaban, A Kejner, SM Rowe, BA Woodworth |
American journal of rhinology & allergy | 2013 |
In Vitro Spatial and Temporal Analysis of Mycoplasma pneumoniae Colonization of Human Airway Epithelium
OA Prince, TM Krunkosky, DC Krause, BA McCormick |
Infection and immunity | 2013 |
Enhanced response to pulmonary Streptococcus pneumoniae infection is associated with primary ciliary dyskinesia in mice lacking Pcdp1 and Spef2
CW McKenzie, JM Klonoski, T Maier, G Trujillo, PF Vitiello, VC Huber, L Lee |
Cilia | 2013 |
Myb promotes centriole amplification and later steps of the multiciliogenesis program
FE Tan, EK Vladar, L Ma, LC Fuentealba, R Hoh, FH Espinoza, JD Axelrod, A Alvarez-Buylla, T Stearns, C Kintner, MA Krasnow |
Development (Cambridge, England) | 2013 |
Cellular and Molecular Biology of Airway Mucins
Lillehoj EP, Kato K, Lu W, Kim KC |
International review of cell and molecular biology | 2013 |
Infectious Mechanisms Regulating Susceptibility to Acute Exacerbations of COPD
Provost K, Desai H, Sethi S |
2013 | |
Role of Epithelial Cells in Chronic Inflammatory Lung Disease
Kim V, Kato K, Kim KC, Lillehoj EP |
2013 | |
Detrimental role of the airway mucin Muc5ac during ventilator-induced lung injury
M Koeppen, EN McNamee, KS Brodsky, CM Aherne, M Faigle, GP Downey, SP Colgan, CM Evans, DA Schwartz, HK Eltzschig |
Mucosal Immunology | 2012 |
Acquired Cilia Dysfunction in Chronic Rhinosinusitis
D Gudis, KQ Zhao, NA Cohen |
American journal of rhinology & allergy | 2012 |
An advanced stochastic model for mucociliary particle clearance in cystic fibrosis lungs
R Sturm |
Journal of Thoracic Disease | 2012 |
A Periciliary Brush Promotes the Lung Health by Separating the Mucus Layer from Airway Epithelia
B Button, LH Cai, C Ehre, M Kesimer, DB Hill, JK Sheehan, RC Boucher, M Rubinstein |
Science | 2012 |
Bead-size directed distribution of Pseudomonas aeruginosa results in distinct inflammatory response in a mouse model of chronic lung infection: Distribution of pulmonary inflammation
LJ Christophersen, H Trøstrup, DS Damlund, T Bjarnsholt, K Thomsen, PØ Jensen, HP Hougen, N Høiby, C Moser |
Clinical & Experimental Immunology | 2012 |
Advances in Cell and Gene-based Therapies for Cystic Fibrosis Lung Disease
M Oakland, PL Sinn, PB McCray |
Molecular Therapy | 2012 |
Triiodothyronine Represses MUC5AC Expression by Antagonizing Sp1 Binding to Its Promoter in Human Bronchial Epithelial HBE16 Cells
X Wang, Q Li, X Zhou, VP Kolosov, JM Perelman |
Journal of Biomedicine and Biotechnology | 2012 |
CFTR Regulates Early Pathogenesis of Chronic Obstructive Lung Disease in βENaC-Overexpressing Mice
B Johannesson, S Hirtz, J Schatterny, C Schultz, MA Mall |
PloS one | 2012 |
PmrB Mutations Promote Polymyxin Resistance of Pseudomonas aeruginosa Isolated from Colistin-Treated Cystic Fibrosis Patients
SM Moskowitz, MK Brannon, N Dasgupta, M Pier, N Sgambati, AK Miller, SE Selgrade, SI Miller, M Denton, SP Conway, HK Johansen, N Høiby |
Antimicrobial agents and chemotherapy | 2012 |
Host Evasion by Burkholderia cenocepacia
S Ganesan, US Sajjan |
Frontiers in Cellular and Infection Microbiology | 2012 |
Effects of second hand smoke on airway secretion and mucociliary clearance
Y Liu, YP Di |
Frontiers in physiology | 2012 |
Clinical translation of RNAi-based treatments for respiratory diseases
B Ballarín-González, TB Thomsen, KA Howard |
Drug Delivery and Translational Research | 2012 |
Monitoring airway mucus flow and ciliary activity with optical coherence tomography
AL Oldenburg, RK Chhetri, DB Hill, B Button |
Biomedical Optics Express | 2012 |
Near-Universal Prevalence of Pneumocystis and Associated Increase in Mucus in the Lungs of Infants With Sudden Unexpected Death
SL Vargas, CA Ponce, M Gallo, F Perez, JF Astorga, R Bustamante, M Chabe, I Durand-Joly, P Iturra, RF Miller, EM Aliouat, E Dei-Cas |
Clinical Infectious Diseases | 2012 |
Pharmaceutical nanoparticles and the mucin biopolymer barrier
G Aljayyoussi, M Abdulkarim, P Griffiths, M Gumbleton |
BioImpacts : BI | 2012 |
The susceptibility of T5-TG12 of the CFTR gene in chronic bronchitis occurrence in a Chinese population in Jiangsu province, China
P Wang, S Naruse, H Yin, Z Yu, T Zhuang, W Ding, Y Wu, M Wei |
Journal of Biomedical Research | 2012 |
Ciliated cells of pseudostratified airway epithelium do not become mucous cells after ovalbumin challenge
A Pardo-Saganta, BM Law, M Gonzalez-Celeiro, V Vinarsky, J Rajagopal |
American journal of respiratory cell and molecular biology | 2012 |
Using unfixed, frozen tissues to study natural mucin distribution
M Cohen, NM Varki, MD Jankowski, P Gagneux |
Journal of visualized experiments : JoVE | 2012 |
Molecular organization of the mucins and glycocalyx underlying mucus transport over mucosal surfaces of the airways
M Kesimer, C Ehre, KA Burns, CW Davis, JK Sheehan, RJ Pickles |
Mucosal Immunology | 2012 |
Identification of SPLUNC1's ENaC-inhibitory domain yields novel strategies to treat sodium hyperabsorption in cystic fibrosis airways
CA Hobbs, MG Blanchard, S Kellenberger, S Bencharit, R Cao, M Kesimer, WG Walton, MR Redinbo, MJ Stutts, R Tarran |
The FASEB Journal | 2012 |
MUC2 protein expression status is useful in assessing the effects of hyperthermic intraperitoneal chemotherapy for peritoneal dissemination of colon cancer
Y Fujishima, T Goi, Y Kimura, Y Hirono, K Katayama, A Yamaguchi |
International journal of oncology | 2012 |
Epithelial Na⁺ channel activity in human airway epithelial cells: the role of serum and glucocorticoid-inducible kinase 1
GB Watt, NA Ismail, AG Caballero, SC Land, SM Wilson |
British Journal of Pharmacology | 2012 |
Allergic Host Defenses
NW Palm, RK Rosenstein, R Medzhitov |
Nature | 2012 |
CFTR, mucins, and mucus obstruction in cystic fibrosis
SM Kreda, CW Davis, MC Rose |
Cold Spring Harbor Perspectives in Medicine | 2012 |
Glucose transporter/T1R3-expressing cells in rat tracheal epithelium
F Merigo, D Benati, M Cristofoletti, F Amarù, F Osculati, A Sbarbati |
Journal of Anatomy | 2012 |
Pulmonary delivery of therapeutic siRNA
JK Lam, W Liang, HK Chan |
Advanced Drug Delivery Reviews | 2012 |
A poly(ethylene glycol)-based surfactant for formulation of drug-loaded mucus penetrating particles
O Mert, SK Lai, L Ensign, M Yang, YY Wang, J Wood, J Hanes |
Journal of Controlled Release | 2012 |
Expression of dual oxidases and secreted cytokines in chronic rhinosinusitis: DUOX1/DUOX2 and secreted cytokines in CRS
DY Cho, JV Nayak, DT Bravo, W Le, A Nguyen, JA Edward, PH Hwang, B Illek, H Fischer |
International Forum of Allergy & Rhinology | 2012 |
Glucocorticoid Receptor and Histone Deacetylase–2 Mediate Dexamethasone-Induced Repression of MUC5AC Gene Expression
Y Chen, AM Watson, CD Williamson, M Rahimi, C Liang, AM Colberg-Poley, MC Rose |
American journal of respiratory cell and molecular biology | 2012 |
Hemagglutinin from the H5N1 Virus Activates Janus Kinase 3 to Dysregulate Innate Immunity
W Xu, M Chen, N Ge, J Xu, SG Zheng |
PloS one | 2012 |
Methods in Molecular Biology
LH Abdullah, C Wolber, M Kesimer, JK Sheehan, CW Davis |
Methods in molecular biology (Clifton, N.J.) | 2012 |
Phosphodiesterase 4B Mediates Extracellular Signal-regulated Kinase-dependent Up-regulation of Mucin MUC5AC Protein by Streptococcus pneumoniae by Inhibiting cAMP-protein Kinase A-dependent MKP-1 Phosphatase Pathway
J Lee, K Komatsu, BC Lee, JH Lim, H Jono, H Xu, H Kai, ZJ Zhang, C Yan, JD Li |
The Journal of biological chemistry | 2012 |
Structure and function of the Type III secretion system of Pseudomonas aeruginosa.
Galle M, Carpentier I, Beyaert R |
Current protein & peptide science | 2012 |
Inhaled innate immune ligands to prevent pneumonia
SE Evans, MJ Tuvim, CJ Fox, N Sachdev, L Gibiansky, BF Dickey |
British Journal of Pharmacology | 2011 |
The role of female hormones on lung function in chronic lung diseases
A Tam, D Morrish, S Wadsworth, D Dorscheid, SF Man, DD Sin |
BMC Women's Health | 2011 |
Improvement of adenoviral vector-mediated gene transfer to airway epithelia by folate-modified anionic liposomes
Z Zhong, Y Wan, J Han, S Shi, Z Zhang, X Sun |
International Journal of Nanomedicine | 2011 |
Impact of topically-applied ipd-giucose on tracheal mucociliary clearance after warm and cold ischemia: short communication
AE de Azevedo-Pereira, JA Saka, KA de Oliveira, R Pazetti, PM Pêgo-Fernandes, FB Jatene |
Clinics (São Paulo, Brazil) | 2011 |
Embryonic frog epidermis: a model for the study of cell-cell interactions in the development of mucociliary disease
E Dubaissi, N Papalopulu |
Disease models & mechanisms | 2011 |
Characterization of Virulence Factors of Staphylococcus aureus: Novel Function of Known Virulence Factors That Are Implicated in Activation of Airway Epithelial Proinflammatory Response
J Bien, O Sokolova, P Bozko |
Journal of Pathogens | 2011 |
Host Defense and the Airway Epithelium: Frontline Responses That Protect against Bacterial Invasion and Pneumonia
NA Eisele, DM Anderson |
Journal of Pathogens | 2011 |
Models for oral uptake of nanoparticles in consumer products
E Fröhlich, E Roblegg |
Toxicology | 2011 |
Ciliopathies: The Central Role of Cilia in a Spectrum of Pediatric Disorders
TW Ferkol, MW Leigh |
The Journal of Pediatrics | 2011 |
Measurement of the Airway Surface Liquid Volume with Simple Light Refraction Microscopy
PR Harvey, R Tarran, S Garoff, MM Myerburg |
American journal of respiratory cell and molecular biology | 2011 |
The Role of TLR2 and Bacterial Lipoprotein in Enhancing Airway Inflammation and Immunity
AA Lugade, PN Bogner, TF Murphy, Y Thanavala |
Frontiers in immunology | 2011 |
Effect of Polarized Release of CXC-Chemokines from Wild-Type and Cystic Fibrosis Murine Airway Epithelial Cells
MM Farberman, A Ibricevic, TD Joseph, KT Akers, R Garcia-Medina, S Crosby, LL Clarke, SL Brody, TW Ferkol |
American journal of respiratory cell and molecular biology | 2011 |
Mucociliary interactions and mucus dynamics in ciliated human bronchial epithelial cell cultures
PR Sears, CW Davis, M Chua, JK Sheehan |
AJP Lung Cellular and Molecular Physiology | 2011 |
Biodegradable Nanoparticles Composed Entirely of Safe Materials that Rapidly Penetrate Human Mucus
M Yang, SK Lai, YY Wang, W Zhong, C Happe, M Zhang, J Fu, J Hanes |
Angewandte Chemie (International ed. in English) | 2011 |
Limited effects of Muc1 deficiency on mouse adenovirus type 1 respiratory infection
Y Nguyen, MC Procario, SL Ashley, WK O’Neal, RJ Pickles, JB Weinberg |
Virus Research | 2011 |
PhoQ Mutations Promote Lipid A Modification and Polymyxin Resistance of Pseudomonas aeruginosa Found in Colistin-Treated Cystic Fibrosis Patients
AK Miller, MK Brannon, L Stevens, HK Johansen, SE Selgrade, SI Miller, N Høiby, SM Moskowitz |
Antimicrobial agents and chemotherapy | 2011 |
NF-κB Mediates IL-1β– and IL-17A–Induced MUC5B Expression in Airway Epithelial Cells
T Fujisawa, MM Chang, S Velichko, P Thai, LY Hung, F Huang, N Phuong, Y Chen, R Wu |
American journal of respiratory cell and molecular biology | 2011 |
Gene therapy for cystic fibrosis lung disease
Sumner-Jones SG, Gill DR, Hyde SC |
2011 | |
Airway Surface Liquid Volume Regulation Determines Different Airway Phenotypes in Liddle Compared with βENaC-overexpressing Mice*
MA Mall, B Button, B Johannesson, Z Zhou, A Livraghi, RA Caldwell, SC Schubert, C Schultz, WK O'Neal, S Pradervand, E Hummler, BC Rossier, BR Grubb, RC Boucher |
The Journal of biological chemistry | 2010 |
Human Alveolar Type II Cells Secrete and Absorb Liquid in Response to Local Nucleotide Signaling*
PF Bove, BR Grubb, SF Okada, CM Ribeiro, TD Rogers, SH Randell, WK O'Neal, RC Boucher |
The Journal of biological chemistry | 2010 |
Inducible Innate Resistance of Lung Epithelium to Infection
SE Evans, Y Xu, MJ Tuvim, BF Dickey |
Annual Review of Physiology | 2010 |
Endotoxins: Structure, Function and Recognition
X Wang, PJ Quinn |
2010 | |
Regulation of the epithelial Na+ channel and airway surface liquid volume by serine proteases
EA Gaillard, P Kota, M Gentzsch, NV Dokholyan, MJ Stutts, R Tarran |
Pflügers Archiv - European Journal of Physiology | 2010 |
Mucus secretion from individual submucosal glands of the ferret trachea
HJ Cho, NS Joo, JJ Wine |
American journal of physiology. Lung cellular and molecular physiology | 2010 |
Planar cell polarity signaling, cilia and polarized ciliary beating
JB Wallingford |
Current Opinion in Cell Biology | 2010 |
Transcriptome profiles of carcinoma-in-situ and invasive non-small cell lung cancer as revealed by SAGE
KM Lonergan, R Chari, BP Coe, IM Wilson, MS Tsao, RT Ng, C Macaulay, S Lam, WL Lam |
PloS one | 2010 |
Airway Mucus Function and Dysfunction
JV Fahy, BF Dickey |
New England Journal of Medicine | 2010 |
SPLUNC1 expression reduces surface levels of the epithelial sodium channel (ENaC) in Xenopus laevis oocytes
BM Rollins, A Garcia-Caballero, MJ Stutts, R Tarran |
Channels (Austin, Tex.) | 2010 |
Primary Ciliary Dyskinesia in Amish Communities
H Lie, MA Zariwala, C Helms, AM Bowcock, JL Carson, DE Brown, MJ Hazucha, J Forsen, D Molter, MR Knowles, MW Leigh, TW Ferkol |
The Journal of Pediatrics | 2010 |
Tissue Distribution of Murine Muc19/Smgc Gene Products
B Das, MN Cash, AR Hand, A Shivazad, SS Grieshaber, B Robinson, DJ Culp |
Journal of Histochemistry & Cytochemistry | 2010 |
Klebsiella pneumoniae Capsule Polysaccharide Impedes the Expression of β-Defensins by Airway Epithelial Cells
D Moranta, V Regueiro, C March, E Llobet, J Margareto, E Larrate, J Garmendia, JA Bengoechea |
Infection and immunity | 2010 |
Substance P stimulates human airway submucosal gland secretion mainly via a CFTR-dependent process
1. Jae Young Choi 2. Monal Sonecha 3. Nam Soo Joo 4. Mauri E. Krouse 5. Robert C. Robbins 6. David Weill 7. Jeffrey J. Wine. |
Journal of Clinical Investigation | 2009 |
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd |
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology | 2009 |
Innate Immunity to Aspergillus Species
SJ Park, B Mehrad |
Clinical microbiology reviews | 2009 |
Inhaled therapeutics for prevention and treatment of pneumonia
A Safdar, SA Shelburne, SE Evans, BF Dickey |
Expert Opinion on Drug Safety | 2009 |
Endogenous lung stem cells and contribution to disease
JC Snyder, RM Teisanu, BR Stripp |
The Journal of Pathology | 2009 |
Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues
SK Lai, YY Wang, J Hanes |
Advanced Drug Delivery Reviews | 2009 |
SPLUNC1 regulates airway surface liquid volume by protecting ENaC from proteolytic cleavage
A Garcia-Caballero, JE Rasmussen, E Gaillard, MJ Watson, JC Olsen, SH Donaldson, MJ Stutts, R Tarran |
Proceedings of the National Academy of Sciences | 2009 |
Modulation of endocytic trafficking and apical stability of CFTR in primary human airway epithelial cultures
DM Cholon, WK O'Neal, SH Randell, JR Riordan, M Gentzsch |
American journal of physiology. Lung cellular and molecular physiology | 2009 |
Hypoxia inducible factor-1 (HIF-1)-mediated repression of cystic fibrosis transmembrane conductance regulator (CFTR) in the intestinal epithelium
W Zheng, J Kuhlicke, K Jäckel, HK Eltzschig, A Singh, M Sjöblom, B Riederer, C Weinhold, U Seidler, SP Colgan, J Karhausen |
The FASEB Journal | 2009 |
The antioxidant role of thiocyanate in the pathogenesis of cystic fibrosis and other inflammation-related diseases
Y Xu, S Szép, Z Lu |
Proceedings of the National Academy of Sciences | 2009 |
Conditional deletion of dnaic1 in a murine model of primary ciliary dyskinesia causes chronic rhinosinusitis
LE Ostrowski, W Yin, TD Rogers, KB Busalacchi, M Chua, WK O'Neal, BR Grubb |
American journal of respiratory cell and molecular biology | 2009 |
Nanoparticles reveal that human cervicovaginal mucus is riddled with pores larger than viruses
SK Lai, YY Wang, K Hida, R Cone, J Hanes |
Proceedings of the National Academy of Sciences | 2009 |
Proton secretion in freshly excised sinonasal mucosa from asthma and sinusitis patients
DY Cho, M Hajighasemi, PH Hwang, B Illek, H Fischer |
American journal of rhinology & allergy | 2009 |
Biodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier
BC Tang, M Dawson, SK Lai, YY Wang, JS Suk, M Yang, P Zeitlin, MP Boyle, J Fu, J Hanes |
Proceedings of the National Academy of Sciences | 2009 |
Absorptive clearance of DTPA as an aerosol-based biomarker in the cystic fibrosis airway
TE Corcoran, KM Thomas, MM Myerburg, A Muthukrishnan, L Weber, R Frizzell, JM Pilewski |
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology | 2009 |
Purinergic receptors in airway epithelia
ER Lazarowski, RC Boucher |
Current Opinion in Pharmacology | 2009 |
Altering mucus rheology to "solidify" human mucus at the nanoscale
SK Lai, YY Wang, R Cone, D Wirtz, J Hanes |
PloS one | 2009 |
Chronic intermittent mechanical stress increases MUC5AC protein expression
JA Park, DJ Tschumperlin |
American journal of respiratory cell and molecular biology | 2009 |
Micro- and macrorheology of mucus
SK Lai, YY Wang, D Wirtz, J Hanes |
Advanced Drug Delivery Reviews | 2009 |
Mucus hypersecretion in asthma: causes and effects:
CM Evans, K Kim, MJ Tuvim, BF Dickey |
Current Opinion in Pulmonary Medicine | 2009 |
Pseudomonas aeruginosa Type III secretion system interacts with phagocytes to modulate systemic infection of zebrafish embryos
MK Brannon, JM Davis, JR Mathias, CJ Hall, JC Emerson, PS Crosier, A Huttenlocher, L Ramakrishnan, SM Moskowitz |
Cellular Microbiology | 2009 |
Clinical and genetic aspects of primary ciliary dyskinesia/Kartagener syndrome
MW Leigh, JE Pittman, JL Carson, TW Ferkol, SD Dell, SD Davis, MR Knowles, MA Zariwala |
Genetics in Medicine | 2009 |
Metagenomic Analysis of Respiratory Tract DNA Viral Communities in Cystic Fibrosis and Non-Cystic Fibrosis Individuals
D Willner, M Furlan, M Haynes, R Schmieder, FE Angly, J Silva, S Tammadoni, B Nosrat, D Conrad, F Rohwer, JA Gold |
PloS one | 2009 |
Klebsiella pneumoniae Increases the Levels of Toll-Like Receptors 2 and 4 in Human Airway Epithelial Cells
V Regueiro, D Moranta, MA Campos, J Margareto, J Garmendia, JA Bengoechea |
Infection and immunity | 2009 |
Synaptotagmin 2 Couples Mucin Granule Exocytosis to Ca2+ Signaling from Endoplasmic Reticulum
MJ Tuvim, AR Mospan, KA Burns, M Chua, PJ Mohler, E Melicoff, R Adachi, Z Ammar-Aouchiche, CW Davis, BF Dickey |
The Journal of biological chemistry | 2009 |
Histo-blood group gene polymorphisms as potential genetic modifiers of infection and cystic fibrosis lung disease severity.
Taylor-Cousar JL, Zariwala MA, Burch LH, Pace RG, Drumm ML, Calloway H, Fan H, Weston BW, Wright FA, Knowles MR |
PloS one | 2009 |
The Role of Innate Immunity in the Pathogenesis of Chronic Rhinosinusitis
Lane AP |
Current Allergy and Asthma Reports | 2009 |
17beta-Estradiol Inhibits Calcium-Dependent Airway Surface Liquid Volume Homeostasis in Cystic Fibrosis Airway Epithelia
Ray D. Coakley, Hengrui Sun, Julia E. Rasmussen, Lucy A. Chambers, James R. Stackhouse, Seiko F. Okada, Ingrid Fricks, Steven L. Young & Robert Tarran |
Journal of Clinical Investigation | 2008 |
Stimulation of lung innate immunity protects against lethal pneumococcal pneumonia in mice
CG Clement, SE Evans, CM Evans, D Hawke, R Kobayashi, PR Reynolds, SJ Moghaddam, BL Scott, E Melicoff, R Adachi, BF Dickey, MJ Tuvim |
American journal of respiratory and critical care medicine | 2008 |
Mutation of murine adenylate kinase 7 underlies a primary ciliary dyskinesia phenotype
A Fernandez-Gonzalez, S Kourembanas, TA Wyatt, SA Mitsialis |
American journal of respiratory cell and molecular biology | 2008 |
Nontypeable Haemophilus influenzae induces COX-2 and PGE2 expression in lung epithelial cells via activation of p38 MAPK and NF-kappa B
F Xu, Z Xu, R Zhang, Z Wu, JH Lim, T Koga, JD Li, H Shen |
Respiratory Research | 2008 |
Th2 cytokines associated with chronic rhinosinusitis with polyps down-regulate the antimicrobial immune function of human sinonasal epithelial cells
M Ramanathan, WK Lee, EW Spannhake, AP Lane |
American journal of rhinology | 2008 |
Flagellin-stimulated Cl- secretion and innate immune responses in airway epithelia: role for p38
B Illek, Z Fu, C Schwarzer, T Banzon, S Jalickee, SS Miller, TE Machen |
American journal of physiology. Lung cellular and molecular physiology | 2008 |
Front-runners for pharmacotherapeutic correction of the airway ion transport defect in cystic fibrosis
MT Clunes, RC Boucher |
Current Opinion in Pharmacology | 2008 |
Clinical practice and genetic counseling for cystic fibrosis and CFTR-related disorders
SM Moskowitz, JF Chmiel, DL Sternen, E Cheng, RL Gibson, SG Marshall, GR Cutting |
Genetics in Medicine | 2008 |
Requirements for two proximal NF-kappaB binding sites and IkappaB-zeta in IL-17A-induced human beta-defensin 2 expression by conducting airway epithelium
CY Kao, C Kim, F Huang, R Wu |
The Journal of biological chemistry | 2008 |
Addressing the PEG mucoadhesivity paradox to engineer nanoparticles that "slip" through the human mucus barrier
YY Wang, SK Lai, JS Suk, A Pace, R Cone, J Hanes |
Angewandte Chemie (International ed. in English) | 2008 |
Tracheobronchial air-liquid interface cell culture: a model for innate mucosal defense of the upper airways?
M Kesimer, S Kirkham, RJ Pickles, AG Henderson, NE Alexis, G Demaria, D Knight, DJ Thornton, JK Sheehan |
American journal of physiology. Lung cellular and molecular physiology | 2008 |
A2B adenosine receptors regulate the mucus clearance component of the lung's innate defense system
BM Rollins, M Burn, RD Coakley, LA Chambers, AJ Hirsh, MT Clunes, MI Lethem, SH Donaldson, R Tarran |
American journal of respiratory cell and molecular biology | 2008 |
Allergen-induced airway hyperresponsiveness is absent in ecto-5′-nucleotidase (CD73)-deficient mice
R Schreiber, H Castrop, K Kunzelmann |
Pflügers Archiv - European Journal of Physiology | 2008 |
Coupling of airway ciliary activity and mucin secretion to mechanical stresses by purinergic signaling
CW Davis, E Lazarowski |
Respiratory Physiology & Neurobiology | 2008 |
Diminished Self-Chaperoning Activity of the ΔF508 Mutant of CFTR Results in Protein Misfolding
AW Serohijos, T Hegedűs, JR Riordan, NV Dokholyan, EI Shakhnovich |
PLoS computational biology | 2008 |
MKP1 Regulates the Induction of MUC5AC Mucin by Streptococcus pneumoniae Pneumolysin by Inhibiting the PAK4-JNK Signaling Pathway
UH Ha, JH Lim, HJ Kim, W Wu, S Jin, H Xu, JD Li |
The Journal of biological chemistry | 2008 |
Role of mechanical stress in regulating airway surface hydration and mucus clearance rates.
Button B, Boucher RC |
Respiratory Physiology & Neurobiology | 2008 |
Extracellular barriers in respiratory gene therapy.
Sanders N, Rudolph C, Braeckmans K, De Smedt SC, Demeester J |
Advanced Drug Delivery Reviews | 2008 |
Lung Defenses
Kobzik L |
2008 | |
VIP and carbachol cause synergistic airway gland secretion that is lost in cystic fibrosis
Jae Young Choi, Nam Soo Joo, Mauri E. Krouse, Jin V. Wu, Robert C. Robbins, Juan P. Ianowski, John W. Hanrahan Jeffrey J. Wine |
Journal of Clinical Investigation | 2007 |
IL-13 regulates cilia loss and foxj1 expression in human airway epithelium
BN Gomperts, LJ Kim, SA Flaherty, BP Hackett |
American journal of respiratory cell and molecular biology | 2007 |
Identification of novel ciliogenesis factors using a new in vivo model for mucociliary epithelial development
JM Hayes, SK Kim, PB Abitua, TJ Park, ER Herrington, A Kitayama, MW Grow, N Ueno, JB Wallingford |
Developmental Biology | 2007 |
Parasympathetic control of airway submucosal glands: central reflexes and the airway intrinsic nervous system
JJ Wine |
Autonomic neuroscience : basic & clinical | 2007 |
Quorum-sensing blockade as a strategy for enhancing host defences against bacterial pathogens
T Bjarnsholt, M Givskov |
Philosophical transactions of the Royal Society of London. Series B, Biological sciences | 2007 |
Liquid movement across the surface epithelium of large airways
LA Chambers, BM Rollins, R Tarran |
Respiratory Physiology & Neurobiology | 2007 |
The immunopathogenesis of chronic obstructive pulmonary disease: insights from recent research
JL Curtis, CM Freeman, JC Hogg |
Proceedings of the American Thoracic Society | 2007 |
Primary Ciliary Dyskinesia: Recent Advances in Pathogenesis, Diagnosis and Treatment
H Lie, T Ferkol |
Drugs | 2007 |
Opposing roles of PAK2 and PAK4 in synergistic induction of MUC5AC mucin by bacterium NTHi and EGF
Y Huang, F Mikami, H Jono, W Zhang, X Weng, T Koga, H Xu, C Yan, H Kai, JD Li |
Biochemical and Biophysical Research Communications | 2007 |
Aquaporin-8 expression is reduced in ileum and induced in colon of patients with ulcerative colitis
Zahn A, Moehle C, Langmann T, Ehehalt R, Autschbach F, Stremmel W, Schmitz G |
World journal of gastroenterology : WJG | 2007 |
Identification of novel ciliogenesis factors using a new in vivo model for mucociliary epithelial development.
Hayes JM, Kim SK, Abitua PB, Park TJ, Herrington ER, Kitayama A, Grow MW, Ueno N, Wallingford JB |
Developmental Biology | 2007 |
Soluble Mediators, Not Cilia, Determine Airway Surface Liquid Volume in Normal and Cystic Fibrosis Superficial Airway Epithelia
R Tarran, L Trout, SH Donaldson, RC Boucher |
The Journal of General Physiology | 2006 |
Neutrophil elastase, an innate immunity effector molecule, represses flagellin transcription in Pseudomonas aeruginosa
A Sonawane, J Jyot, R During, R Ramphal |
Infection and immunity | 2006 |
State of the art. Bronchiolitis in chronic obstructive pulmonary disease
JC Hogg |
Proceedings of the American Thoracic Society | 2006 |
Cerebral microcirculation shear stress levels determine Neisseria meningitidis attachment sites along the blood-brain barrier
E Mairey, A Genovesio, E Donnadieu, C Bernard, F Jaubert, E Pinard, J Seylaz, JC Olivo-Marin, X Nassif, G Duménil |
Journal of Experimental Medicine | 2006 |
Mucociliary and long-term particle clearance in airways of patients with immotile cilia
W Möller, K Häussinger, L Ziegler-Heitbrock, J Heyder |
Respiratory Research | 2006 |
Should patients with acute exacerbation of chronic bronchitis be treated with antibiotics? Advantages of the use of fluoroquinolones
Mensa J, Trilla A |
Clinical Microbiology and Infection | 2006 |
Normal and cystic fibrosis airway surface liquid homeostasis. The effects of phasic shear stress and viral infections
R Tarran, B Button, M Picher, AM Paradiso, CM Ribeiro, ER Lazarowski, L Zhang, PL Collins, RJ Pickles, JJ Fredberg, RC Boucher |
The Journal of biological chemistry | 2005 |
Cystic fibrosis lung disease: genetic influences, microbial interactions, and radiological assessment
SM Moskowitz, RL Gibson, EL Effmann |
Pediatric Radiology | 2005 |
Pathogen-host interactions in Pseudomonas aeruginosa pneumonia
RT Sadikot, TS Blackwell, JW Christman, AS Prince |
American journal of respiratory and critical care medicine | 2005 |
Vasotocin and vasopressin stimulation of the chloride secretion in the human bronchial epithelial cell line, 16HBE14o-
K Bernard, S Bogliolo, J Ehrenfeld |
British Journal of Pharmacology | 2005 |
Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions
BL Schulz, AJ Sloane, LJ Robinson, LT Sebastian, AR Glanville, Y Song, AS Verkman, JL Harry, NH Packer, NG Karlsson |
Biochemical Journal | 2005 |
Inositol polyphosphate derivative inhibits Na+ transport and improves fluid dynamics in cystic fibrosis airway epithelia
M Moody, C Pennington, C Schultz, R Caldwell, C Dinkel, MW Rossi, S McNamara, J Widdicombe, S Gabriel, AE Traynor-Kaplan |
American journal of physiology. Cell physiology | 2005 |
TRPV4 channel is involved in the coupling of fluid viscosity changes to epithelial ciliary activity
YN Andrade, J Fernandes, E Vázquez, JM Fernández-Fernández, M Arniges, TM Sánchez, M Villalón, MA Valverde |
The Journal of Cell Biology | 2005 |
Effect of herpesvirus infection on pancreatic duct cell secretion.
Hegyi P, Ordog B, Rakonczai Z Jr, Takács T, Lonovics J, Szabolcs A, Sári R, Tóth A, Papp JG, Varró A, Kovács MK, Gray MA, Argent BE, Boldogköi Z |
World Journal of Gastroenterology | 2005 |
Pseudomonas aeruginosa regulates flagellin expression as part of a global response to airway fluid from cystic fibrosis patients
MC Wolfgang, J Jyot, AL Goodman, R Ramphal, S Lory |
Proceedings of the National Academy of Sciences | 2004 |
Expression Analysis of a Highly Adherent and Cytotoxic Small Colony Variant of Pseudomonas aeruginosa Isolated from a Lung of a Patient with Cystic Fibrosis
F von Götz, S Häussler, D Jordan, SS Saravanamuthu, D Wehmhöner, A Strüßmann, J Lauber, I Attree, J Buer, B Tümmler, I Steinmetz |
Journal of bacteriology | 2004 |
Lymphocytes in cystic fibrosis lung disease: a tale of two immunities
RB Moss |
Clinical & Experimental Immunology | 2004 |
Responses of well-differentiated airway epithelial cell cultures from healthy donors and patients with cystic fibrosis to Burkholderia cenocepacia infection
U Sajjan, S Keshavjee, J Forstner |
Infection and immunity | 2004 |
Nucleotide release provides a mechanism for airway surface liquid homeostasis
ER Lazarowski, R Tarran, BR Grubb, CA van Heusden, S Okada, RC Boucher |
The Journal of biological chemistry | 2004 |
Ca 2+ dependency of ‘Ca 2+ -independent’ exocytosis in SPOC1 airway goblet cells: Ca 2+ dependency of SPOC1 cell exocytosis
AH Rossi, PR Sears, CW Davis |
The Journal of Physiology | 2004 |
Airway hypersecretion in allergic rhinitis and asthma: New pharmacotherapy
DF Rogers |
Current Allergy and Asthma Reports | 2003 |
Disruptive effects of Anion Secretion Inhibitors on Airway Mucus Morphology in Isolated Perfused Pig Lung
L Trout, MI Townsley, AL Bowden, ST Ballard |
The Journal of Physiology | 2003 |
Antimicrobial polypeptides in host defense of the respiratory tract
Thomas Ganz |
Journal of Clinical Investigation | 2002 |
Cytokines in innate host defense in the lung
Robert Strieter, John A. Belpario, Michael Keane |
Journal of Clinical Investigation | 2002 |
Reduced oxygen concentrations in airway mucus contribute to the early and late pathogenesis of Pseudomonas aeruginosa cystic fibrosis airways infection
Dieter Worlitzsch, Robert Tarran, Martina Ulrich, Ute Schwab, Aynur Cekici, Keith C. Meyer, Peter Birrer, Gabriel Bellon, Jürgen Berger, Tilo Weiß, Konrad Botzenhart, James R. Yankaskas, Scott Randell, Richard C. Boucher, Gerd Döring |
Journal of Clinical Investigation | 2002 |
Regulation of Murine Airway Surface Liquid Volume by CFTR and Ca 2+ -activated Cl − Conductances
R Tarran, ME Loewen, AM Paradiso, JC Olsen, MA Gray, BE Argent, RC Boucher, SE Gabriel |
The Journal of General Physiology | 2002 |
Airway Hydration, Apical K+ Secretion, and the Large-Conductance, Ca2+-activated and Voltage-dependent Potassium (BK) Channel
Adrian Kis, Stefanie Krick, Nathalie Baumlin, Matthias Salathe |
Annals of the American Thoracic Society | |
Probing mucin interaction behavior of magnetic nanoparticles
VN Boya, R Lovett, S Setua, V Gandhi, PK Nagesh, S Khan, M Jaggi, MM Yallapu, SC Chauhan |
Journal of Colloid and Interface Science | 2017 |
Bacterial Pathogens and the Microbiome
TW Vickery, VR Ramakrishnan |
Otolaryngologic Clinics of North America | 2017 |
Effects of Sialic Acid Modifications on Virus Binding and Infection
BR Wasik, KN Barnard, CR Parrish |
Trends in Microbiology | 2016 |
Incidence and risk factors for aspiration pneumonia after cardiovascular surgery in elderly patients
E Miyata, A Tanaka, H Emori, A Taruya, S Miyai, N Sakagoshi |
General Thoracic and Cardiovascular Surgery | 2016 |
Primary Ciliary Dyskinesia
MR Knowles, M Zariwala, M Leigh |
Clinics in Chest Medicine | 2016 |
Synthetic Mucus Nanobarriers for Identification of Glycan-Dependent Primary Influenza A Infection Inhibitors
M Cohen, HP Senaati, CJ Fisher, ML Huang, P Gagneux, K Godula |
ACS Central Science | 2016 |
Gefitinib, an EGFR Tyrosine Kinase inhibitor, Prevents Smoke-Mediated Ciliated Airway Epithelial Cell Loss and Promotes Their Recovery
M Valencia-Gattas, GE Conner, NL Fregien, S Ahmad |
PloS one | 2016 |
Effect of Shear Stress on Pseudomonas aeruginosa Isolated from the Cystic Fibrosis Lung
J Dingemans, P Monsieurs, SH Yu, A Crabbé, KU Förstner, A Malfroot, P Cornelis, RV Houdt |
mBio | 2016 |
The Mucus Barrier to Inhaled Gene Therapy
GA Duncan, J Jung, J Hanes, JS Suk |
Molecular Therapy | 2016 |
Role of CFTR in epithelial physiology
V Saint-Criq, MA Gray |
Cellular and Molecular Life Sciences | 2016 |
Marked increases in mucociliary clearance produced by synergistic secretory agonists or inhibition of the epithelial sodium channel
NS Joo, JH Jeong, HJ Cho, JJ Wine |
Scientific Reports | 2016 |
Ultrahigh-speed, phase-sensitive full-field interferometric confocal microscopy for quantitative microscale physiology
I Sencan, BK Huang, Y Bian, E Mis, MK Khokha, H Cao, M Choma |
Biomedical Optics Express | 2016 |
Staphylococcus aureus Infection Reduces Nutrition Uptake and Nucleotide Biosynthesis in a Human Airway Epithelial Cell Line
P Gierok, M Harms, K Methling, F Hochgräfe, M Lalk |
Metabolites | 2016 |
Identification of essential genes of Pseudomonas aeruginosa for its growth in airway mucus
MA Alrahman, SS Yoon |
The Journal of Microbiology | 2016 |
Validation of antibody reagents for mucin analysis in chronic inflammatory airway diseases
T Krause, N Röckendorf, KI Gaede, K Ramaker, H Sinnecker, A Frey |
mAbs | 2016 |
Allergic Aspergillus Rhinosinusitis
A Chakrabarti, H Kaur |
Journal of Fungi | 2016 |
Measuring Airway Surface Liquid Depth in Ex Vivo Mouse Airways by X-Ray Imaging for the Assessment of Cystic Fibrosis Airway Therapies
KS Morgan, M Donnelley, DM Paganin, A Fouras, N Yagi, Y Suzuki, A Takeuchi, K Uesugi, RC Boucher, DW Parsons, KK Siu, D Hartl |
PloS one | 2013 |
LRRC6 Mutation Causes Primary Ciliary Dyskinesia with Dynein Arm Defects
A Horani, TW Ferkol, D Shoseyov, MG Wasserman, YS Oren, B Kerem, I Amirav, M Cohen-Cymberknoh, SK Dutcher, SL Brody, O Elpeleg, E Kerem, SF Grant |
PloS one | 2013 |
PKCθ Synergizes with TLR-Dependent TRAF6 Signaling Pathway to Upregulate MUC5AC Mucin via CARMA1
H Jono, JH Lim, H Xu, JD Li, AJ Ratner |
PloS one | 2012 |
Suppression of Adenosine-Activated Chloride Transport by Ethanol in Airway Epithelia
SV Raju, G Wang, Z Zhang |
PloS one | 2012 |
Mucin Variable Number Tandem Repeat Polymorphisms and Severity of Cystic Fibrosis Lung Disease: Significant Association with MUC5AC
XL Guo, RG Pace, JR Stonebraker, CW Commander, AT Dang, ML Drumm, A Harris, F Zou, DM Swallow, FA Wright, WK O'Neal, MR Knowles, T Eckle |
PloS one | 2011 |
Defective Fluid Secretion from Submucosal Glands of Nasal Turbinates from CFTR-/- and CFTRΔF508/ΔF508 Pigs
HJ Cho, NS Joo, JJ Wine, N Vij |
PloS one | 2011 |
Serotonin Increases Cilia-Driven Particle Transport via an Acetylcholine-Independent Pathway in the Mouse Trachea
P König, B Krain, G Krasteva, W Kummer, M Rojas |
PloS one | 2009 |
Risk of high blood pressure in salt workers working near salt milling plants: A cross-sectional and interventional study
KR Haldiya, ML Mathur, R Sachdev, HN Saiyed |
Environmental Health | 2005 |
Cell Jamming in the Airway Epithelium
Jin-Ah Park, Jeffrey J. Fredberg |
Annals of the American Thoracic Society | |
Reduced mucociliary clearance in old mice is associated with a decrease in Muc5b mucin
BR Grubb, A Livraghi-Butrico, TD Rogers, W Yin, B Button, LE Ostrowski |
American journal of physiology. Lung cellular and molecular physiology | 2016 |
Epithelial Electrolyte Transport Physiology and the Gasotransmitter Hydrogen Sulfide
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