Functional and clinical characterization of KCNJ2 mutations associated with LQT7 (Andersen syndrome)
Martin Tristani-Firouzi, … , Louis J. Ptacek, Rabi Tawil
Martin Tristani-Firouzi, … , Louis J. Ptacek, Rabi Tawil
Published August 1, 2002
Citation Information: J Clin Invest. 2002;110(3):381-388. https://doi.org/10.1172/JCI15183.
View: Text | PDF
Article Genetics

Functional and clinical characterization of KCNJ2 mutations associated with LQT7 (Andersen syndrome)

Abstract

Research Article

Authors

Martin Tristani-Firouzi, Judy L. Jensen, Matthew R. Donaldson, Valeria Sansone, Giovanni Meola, Angelika Hahn, Said Bendahhou, Hubert Kwiecinski, Anna Fidzianska, Nikki Plaster, Ying-Hui Fu, Louis J. Ptacek, Rabi Tawil

×

Figure 3

Options: View larger image (or click on image) Download as PowerPoint
Representative ECGs from AS subjects. (a) ECG demonstrating prolongation...
Representative ECGs from AS subjects. (a) ECG demonstrating prolongation of the QT interval. (b) ECG traces demonstrating a short run of nonsustained polymorphic VT followed by bigeminy (normal QRS complex alternating with a premature ventricular complex). Ventricular arrhythmias dominated the rhythm of this subject throughout the day. (c) Bidirectional VT (note alternating QRS axis polarity) degenerating into a brief run of polymorphic VT. (d) ECG trace demonstrating prominent U wave (indicated by arrows).