Functional redundancy of Rab27 proteins and the pathogenesis of Griscelli syndrome
Duarte C. Barral, … , Kalwant S. Authi, Miguel C. Seabra
Duarte C. Barral, … , Kalwant S. Authi, Miguel C. Seabra
Published July 15, 2002
Citation Information: J Clin Invest. 2002;110(2):247-257. https://doi.org/10.1172/JCI15058.
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Article Genetics

Functional redundancy of Rab27 proteins and the pathogenesis of Griscelli syndrome

Abstract

Research Article

Authors

Duarte C. Barral, José S. Ramalho, Ross Anders, Alistair N. Hume, Holly J. Knapton, Tanya Tolmachova, Lucy M. Collinson, David Goulding, Kalwant S. Authi, Miguel C. Seabra

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Figure 3

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EM of ashen platelets. Platelets were isolated, fixed, and processed for...
EM of ashen platelets. Platelets were isolated, fixed, and processed for EM as described under Methods. Ashen (ash/ash) platelets (a) appear normal when compared with heterozygous (+/ash) controls (b). Typical dense granules (arrowheads) are shown. The granules are electron dense due to their high calcium content. Bars, 1 μm.