Research Article
Christopher Heeschen, Michael Weis, Alexandra Aicher, Stefanie Dimmeler, John P. Cooke
Title and authors | Publication | Year |
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The Impact of Potent Addictive Substances on Angiogenic Behavior: A Comprehensive Review.
Al-Eitan LN, Alahmad SZ, Khair IY |
Current neuropharmacology | 2025 |
Synthesis of acetylcholine by podocytes is a key mechanism for kidney self-defense in glomerulonephritis
Luan Truong, Jessica Trostel, Carlos Roncal, Gabriel Cara-Fuentes, Makoto Miyazaki, Shinobu Miyazaki-Anzai, Ana Andres-Hernando, Fumihiko Sasai, Miguel Lanaspa, Richard Johnson, Gabriela Garcia |
Journal of the American Society of Nephrology : JASN | 2024 |
Assessment of the alpha 7 nicotinic acetylcholine receptor as an imaging marker of cardiac repair-associated processes using NS14490
Reid VJ, McLoughlin WK, Pandya K, Stott H, Iškauskienė M, Šačkus A, Marti JA, Kurian D, Wishart TM, Lucatelli C, Peters D, Gray GA, Baker AH, Newby DE, Hadoke PW, Tavares AA, MacAskill MG |
EJNMMI Research | 2024 |
Involvement of neuronal factors in tumor angiogenesis and the shaping of the cancer microenvironment
Shalabi S, Belayachi A, Larrivée B |
Frontiers in immunology | 2024 |
Fe3O4@Chitosan@ZIF-8@RVG29, an anti-glioma nanoplatform guided by fixed and activated by alternating magnetic field
Savari MN |
Scientific Reports | 2024 |
The angiogenic role of the alpha 9-nicotinic acetylcholine receptor in triple-negative breast cancers.
Ochirbat S, Kan TC, Hsu CC, Huang TH, Chuang KH, Chen M, Cheng CC, Chang CC, Rahayu S, Chang J |
Angiogenesis | 2024 |
The double-edged nature of nicotine: toxicities and therapeutic potentials
Cao Y, Sun J, Wang X, Zhang X, Tian H, Huang L, Huang Z, Zhang Y, Zhang J, Li L, Zhou S |
Frontiers in Pharmacology | 2024 |
The controversial effect of smoking and nicotine in SARS-CoV-2 infection.
Salehi Z, Motlagh Ghoochani BFN, Hasani Nourian Y, Jamalkandi SA, Ghanei M |
Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology | 2023 |
Optogenetic stimulation of basal forebrain cholinergic neurons prevents neuroinflammation and neuropsychiatric manifestations in pristane induced lupus mice.
Yun Y, Wang X, Xu J, Chen J, Wang X, Yang P, Qin L |
Behavioral and brain functions : BBF | 2023 |
The Influence of Nicotine on Trophoblast-Derived Exosomes in a Mouse Model of Pathogenic Preeclampsia.
Kubo A, Matsubara K, Matsubara Y, Nakaoka H, Sugiyama T |
International journal of molecular sciences | 2023 |
Activation of a non-neuronal cholinergic system in visceral white adipose tissue of obese mice and humans
Severi I, Perugini J, Ruocco C, Coppi L, Pedretti S, Di Mercurio E, Senzacqua M, Ragni M, Imperato G, Valerio A, Mitro N, Crestani M, Nisoli E, Giordano A |
Molecular Metabolism | 2023 |
Electronic Cigarette Use and the Risk of Cardiovascular Diseases
J Espinoza-Derout, X Shao, C Lao, K Hasan, J Rivera, M Jordan, V Echeverria, K Roos, A Sinha-Hikim, T Friedman |
Frontiers in Cardiovascular Medicine | 2022 |
The potential role of nicotine in breast cancer initiation, development, angiogenesis, invasion, metastasis, and resistance to therapy.
Khodabandeh Z, Valilo M, Velaei K, Pirpour Tazehkand A |
Breast Cancer | 2022 |
Antioxidant Systems, lncRNAs, and Tunneling Nanotubes in Cell Death Rescue from Cigarette Smoke Exposure
Ferrer JL, Garcia RL |
Cells | 2022 |
Expression, correlation, and prognostic significance of different nicotinic acetylcholine receptors, programed death ligand 1, and dopamine receptor D2 in lung adenocarcinoma
Pal K, Hussain T, Xie H, Li S, Yang P, Mansfield A, Lou Y, Chowdhury S, Mukhopadhyay D |
Frontiers in Oncology | 2022 |
Effects of nicotine and lipopolysaccharide stimulation on adhesion molecules in human gingival endothelial cells.
Sato Y, Maruyama K, Mikami M, Sato S |
Odontology / the Society of the Nippon Dental University | 2022 |
Molecular mechanisms, physiological roles, and therapeutic implications of ion fluxes in bone cells: Emphasis on the cation‐Cl− cotransporters
Garneau AP, Slimani S, Haydock L, Nsimba\u2010Batomene T, Préfontaine FC, Lavoie MM, Tremblay LE, Fiola M, Mac\u2010Way F, Isenring P |
Journal of Cellular Physiology | 2022 |
Alpha7 nicotinic acetylcholine receptor mediates chronic nicotine inhalation-induced cardiopulmonary dysfunction.
Whitehead AK, Fried ND, Li Z, Neelamegam K, Pearson CS, LaPenna KB, Sharp TE, Lefer DJ, Lazartigues E, Gardner JD, Yue X |
Clinical science (London, England : 1979) | 2022 |
⍺7 nicotinic acetylcholine receptor mediates right ventricular fibrosis and diastolic dysfunction in pulmonary hypertension
Alexander Vang, Denielli da Silva Gonçalves Bos, Ana Fernandez-Nicolas, Peng Zhang, Alan R Morrison, Thomas J Mancini, Richard T Clements, Iuliia Polina, Michael W Cypress, Bong Sook Jhun, Edward Hawrot, Ulrike Mende, Jin O-Uchi, Gaurav Choudhary |
JCI Insight | 2021 |
Positron Emission Tomography Techniques to Measure Active Inflammation, Fibrosis and Angiogenesis: Potential for Non-invasive Imaging of Hypertensive Heart Failure
V Balogh, MG MacAskill, PW Hadoke, GA Gray, AA Tavares |
Frontiers in Cardiovascular Medicine | 2021 |
SLURP-1 Controls Growth and Migration of Lung Adenocarcinoma Cells, Forming a Complex With α7-nAChR and PDGFR/EGFR Heterodimer
ML Bychkov, MA Shulepko, OV Shlepova, DS Kulbatskii, IA Chulina, AS Paramonov, LK Baidakova, VN Azev, SG Koshelev, MP Kirpichnikov, ZO Shenkarev, EN Lyukmanova |
Frontiers in Cell and Developmental Biology | 2021 |
The Availability of the α7-Nicotinic Acetylcholine Receptor in Early Identification of Vulnerable Atherosclerotic Plaques: A Study Using a Novel 18F-Label Radioligand PET
D Wang, Y Yao, S Wang, H Zhang, ZX He |
Frontiers in Bioengineering and Biotechnology | 2021 |
Studies on the role of alpha 7 nicotinic acetylcholine receptors in K562 cell proliferation and signaling
GÖ Narin, B Aydın, H Cabadak |
Molecular Biology Reports | 2021 |
Nicotine and vascular dysfunction
AK Whitehead, AP Erwin, X Yue |
Acta physiologica (Oxford, England) | 2021 |
Endothelial to mesenchymal transition contributes to nicotine-induced atherosclerosis
W Qin, L Zhang, Z Li, D Xiao, Y Zhang, H Zhang, JN Mokembo, SM Monayo, NK Jha, P Kopylov, D Shchekochikhin, Y Zhang |
Theranostics | 2020 |
COX-2-derived prostaglandins as mediators of the deleterious effects of nicotine in chronic kidney disease
S Rangarajan, G Rezonzew, P Chumley, H Fatima, MY Golovko, W Feng, P Hua, EA Jaimes |
American journal of physiology. Renal physiology | 2020 |
Intracerebroventricular infusion of donepezil prevents cardiac remodeling and improves the prognosis of chronic heart failure rats
M Li, C Zheng, T Kawada, M Inagaki, K Uemura, M Sugimachi |
The Journal of Physiological Sciences | 2020 |
Impact of Peripheral α7-Nicotinic Acetylcholine Receptors on Cardioprotective Effects of Donepezil in Chronic Heart Failure Rats
M Li, C Zheng, T Kawada, M Inagaki, K Uemura, T Akiyama, M Sugimachi |
Cardiovascular Drugs and Therapy | 2020 |
Role of the α7 Nicotinic Acetylcholine Receptor in the Pathophysiology of Atherosclerosis
I Vieira-Alves, LM Coimbra-Campos, M Sancho, RF da Silva, SF Cortes, VS Lemos |
Frontiers in physiology | 2020 |
Germline Mutation Enrichment in Pathways Controlling Endothelial Cell Homeostasis in Patients with Brain Arteriovenous Malformation: Implication for Molecular Diagnosis
C Scimone, F Granata, M Longo, E Mormina, C Turiaco, AA Caragliano, L Donato, A Sidoti, R DAngelo |
International journal of molecular sciences | 2020 |
Nicotinic-nAChR signaling mediates drug resistance in lung cancer
WL Cheng, KY Chen, KY Lee, PH Feng, SM Wu |
Journal of Cancer | 2020 |
Nicotine Induces Resistance to Erlotinib Therapy in Non-Small-Cell Lung Cancer Cells Treated with Serum from Human Patients
T Imabayashi, J Uchino, H Osoreda, K Tanimura, Y Chihara, N Tamiya, Y Kaneko, T Yamada, K Takayama |
Cancers | 2019 |
Alpha7 nAChR Expression Is Correlated with Arthritis Development and Inhibited by Sinomenine in Adjuvant-Induced Arthritic Rats
C Peng, Q Shi, J Liu, Y Lv, J Li, L Yi, S Bai, L Liu, P Wang, H Zhou, K Huang, Y Dong |
Evidence-Based Complementary and Alternative Medicine | 2019 |
LaSota Strain Expressing The Rabies Virus Glycoprotein (rL-RVG) Suppresses Gastric Cancer by Inhibiting the Alpha 7 Nicotinic Acetylcholine Receptor (α7 nAChR)/Phosphoinositide 3-Kinase (PI3K)/AKT Pathway
X Bu, C Yin, X Zhang, A Zhang, X Shao, Y Zhang, Y Yan |
Medical science monitor : international medical journal of experimental and clinical research | 2019 |
Frontiers in positron emission tomography imaging of the vulnerable atherosclerotic plaque
MG MacAskill, DE Newby, AA Tavares |
Cardiovascular Research | 2019 |
Endothelial Ca2+ Signaling and the Resistance to Anticancer Treatments: Partners in Crime
F Moccia |
International journal of molecular sciences | 2018 |
Isobaric Tag-Based Protein Profiling of a Nicotine-Treated Alpha7 Nicotinic Receptor-Null Human Haploid Cell Line
JA Paulo, SP Gygi |
PROTEOMICS | 2018 |
Methylpiperidinium Iodides as Novel Antagonists for α7 Nicotinic Acetylcholine Receptors
JJ López, J García-Colunga, EG Pérez, A Fierro |
Frontiers in pharmacology | 2018 |
Endogenous CHRNA7-ligand SLURP1 as a potential tumor suppressor and anti-nicotinic factor in pancreatic cancer
VM Throm, D Männle, T Giese, AS Bauer, MM Gaida, J Kopitz, T Bruckner, K Plaschke, SP Grekova, K Felix, T Hackert, NA Giese, O Strobel |
Oncotarget | 2018 |
Roles of Nicotine in the Development of Intracranial Aneurysm Rupture
Y Kamio, T Miyamoto, T Kimura, K Mitsui, H Furukawa, D Zhang, K Yokosuka, M Korai, D Kudo, RJ Lukas, MT Lawton, T Hashimoto |
Stroke; a journal of cerebral circulation | 2018 |
Acetylcholine signaling system in progression of lung cancers
JR Friedman, SD Richbart, JC Merritt, KC Brown, NA Nolan, AT Akers, JK Lau, ZR Robateau, SL Miles, P Dasgupta |
Pharmacology & Therapeutics | 2018 |
Microduplication of 15q13.3 and Microdeletion of 18q21.32 in a Patient with Moyamoya Syndrome
S Luisa, R Ambra, B Gloria, C Fioravante, D Vincenzo, N Sara, A Francesco, R Davide, B Simona, F Giuseppe, G Andrea, G Marina, B Grazia, F Paolo, P Chiara, C Luigi, V Jesus, P Agostino, B Anna |
International journal of molecular sciences | 2018 |
Treatment with Sildenafil and Donepezil Improves Angiogenesis in Experimentally Induced Critical Limb Ischemia
IM Constantinescu, P Bolfa, D Constantinescu, AI Mironiuc, CD Gherman |
BioMed Research International | 2017 |
α-Conotoxins active at α3-containing nicotinic acetylcholine receptors and their molecular determinants for selective inhibition: Conotoxins targeting α3-containing nAChRs
H Cuny, R Yu, HS Tae, SN Kompella, DJ Adams |
British Journal of Pharmacology | 2017 |
α7-nAChR Activation Has an Opposite Effect on Healing of Covered and Uncovered Wounds
JY Li, SK Jiang, LL Wang, MZ Zhang, S Wang, ZF Jiang, YL Liu, H Cheng, M Zhang, R Zhao, DW Guan |
Inflammation | 2017 |
The Nicotinic Cholinergic Pathway Contributes to Retinal Neovascularization in a Mouse Model of Retinopathy of Prematurity
SF Hackett, C Seidel, S Abraham, R Chadha, SD Fortmann, PA Campochiaro, JP Cooke |
Investigative ophthalmology & visual science | 2017 |
Racial disparity in breast cancer: can it be mattered for prognosis and therapy
V Gupta, I Haque, J Chakraborty, S Graff, S Banerjee, SK Banerjee |
Journal of Cell Communication and Signaling | 2017 |
Inhibition of renalase expression and signaling has antitumor activity in pancreatic cancer
X Guo, L Hollander, D MacPherson, L Wang, H Velazquez, J Chang, R Safirstein, C Cha, F Gorelick, GV Desir |
Scientific Reports | 2016 |
Tobacco carcinogen induces both lung cancer and non-alcoholic steatohepatitis and hepatocellular carcinomas in ferrets which can be attenuated by lycopene supplementation: Tobacco carcinogen induces NAFLD, NASH and HCC in ferrets
K Aizawa, C Liu, S Tang, S Veeramachaneni, KQ Hu, DE Smith, XD Wang |
International Journal of Cancer | 2016 |
Silencing A7-nAChR levels increases the sensitivity of gastric cancer cells to ixabepilone treatment
CC Tu, CY Huang, WL Cheng, CS Hung, YJ Chang, PL Wei |
Tumor Biology | 2016 |
Heteromeric α7β2 Nicotinic Acetylcholine Receptors in the Brain
J Wu, Q Liu, P Tang, JD Mikkelsen, J Shen, P Whiteaker, JL Yakel |
Trends in Pharmacological Sciences | 2016 |
The Oncogenic Functions of Nicotinic Acetylcholine Receptors
Y Zhao |
Journal of Oncology | 2016 |
Nicotine-induced protein expression profiling reveals mutually altered proteins across four human cell lines
JA Paulo, SP Gygi |
PROTEOMICS | 2016 |
Biomarkers of Tobacco Smoke Exposure in Racial/Ethnic Groups at High Risk for Lung Cancer
P Fagan, ET Moolchan, P Pohkrel, T Herzog, KD Cassel, I Pagano, AA Franke, JK Kaholokula, A Sy, LA Alexander, DR Trinidad, KL Sakuma, CA Johnson, A Antonio, D Jorgensen, T Lynch, C Kawamoto, MS Clanton |
American journal of public health | 2015 |
Global analysis of protein expression and phosphorylation levels in nicotine-treated pancreatic stellate cells
JA Paulo, A Gaun, SP Gygi |
Journal of Proteome Research | 2015 |
New Insights Into Tobacco-Induced Vascular Disease: Clinical Ramifications
JP Cooke |
Methodist DeBakey Cardiovascular Journal | 2015 |
Nicotine: Carcinogenicity and Effects on Response to Cancer Treatment – A Review
T Sanner, TK Grimsrud |
Frontiers in Oncology | 2015 |
Genetic responses to seasonal variation in altitudinal stress: whole-genome resequencing of great tit in eastern Himalayas
Y Qu, S Tian, N Han, H Zhao, B Gao, J Fu, Y Cheng, G Song, PG Ericson, YE Zhang, D Wang, Q Quan, Z Jiang, R Li, F Lei |
Scientific Reports | 2015 |
Brain protection against ischemic stroke using choline as a new molecular bypass treatment
X Jin, R Wang, H Wang, C Long, H Wang |
Acta Pharmacologica Sinica | 2015 |
CHRFAM7A: a human-specific 7-nicotinic acetylcholine receptor gene shows differential responsiveness of human intestinal epithelial cells to LPS
X Dang, BP Eliceiri, A Baird, TW Costantini |
The FASEB Journal | 2015 |
State-of-the-Art Methods for Evaluation of Angiogenesis and Tissue Vascularization: A Scientific Statement From the American Heart Association
M Simons, K Alitalo, BH Annex, HG Augustin, C Beam, BC Berk, T Byzova, P Carmeliet, W Chilian, JP Cooke, GE Davis, A Eichmann, ML Iruela-Arispe, E Keshet, AJ Sinusas, C Ruhrberg, YJ Woo, S Dimmeler |
Circulation research | 2015 |
Nicotine increases the resistance of lung cancer cells to cisplatin through enhancing Bcl-2 stability
T Nishioka, LY Luo, L Shen, H He, A Mariyannis, W Dai, C Chen |
British Journal of Cancer | 2014 |
Functional properties of ion channels and transporters in tumour vascularization
AF Pla, L Munaron |
Philosophical Transactions of the Royal Society B: Biological Sciences | 2014 |
NMR structures of the human α7 nAChR transmembrane domain and associated anesthetic binding sites
V Bondarenko, DD Mowrey, TS Tillman, E Seyoum, Y Xu, P Tang |
Biochimica et Biophysica Acta (BBA) - Biomembranes | 2014 |
Dopamine D2 receptor agonists inhibit lung cancer progression by reducing angiogenesis and tumor infiltrating myeloid derived suppressor cells
LH Hoeppner, Y Wang, A Sharma, N Javeed, VP van Keulen, E Wang, P Yang, AC Roden, T Peikert, JR Molina, D Mukhopadhyay |
Molecular Oncology | 2014 |
Expression of acetylcholine receptors by experimental rat renal allografts
M Meixner, S Atanasova, W Padberg, V Grau |
BioMed Research International | 2014 |
Idiopathic nodular glomerulosclerosis in Chinese patients: a clinicopathologic study of 20 cases
J Wu, S Yu, V Tejwani, M Mao, AK Muriithi, C Ye, X Zhao, H Gu, C Mei, Q Qian |
Clinical and Experimental Nephrology | 2014 |
Acetylcholinesterase overexpression mediated by oncolytic adenovirus exhibited potent anti-tumor effect
H Xu, Z Shen, J Xiao, Y Yang, W Huang, Z Zhou, J Shen, Y Zhu, XY Liu, L Chu |
BMC Cancer | 2014 |
Arterial Baroreflex Dysfunction Impairs Ischemia-Induced Angiogenesis
C Hao, ZH Huang, SW Song, YQ Shi, XW Cheng, T Murohara, W Lu, DF Su, JL Duan |
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease | 2014 |
Nicotine alters the proteome of two human pancreatic duct cell lines.
Paulo JA |
JOP : Journal of the pancreas | 2014 |
Nicotine signaling and progression of chronic kidney disease in smokers
G Jain, EA Jaimes |
Biochemical Pharmacology | 2013 |
Nicotine and lung cancer
GW Warren, AK Singh |
Journal of carcinogenesis | 2013 |
Nicotinic acetylcholine receptors mediate lung cancer growth
MR Improgo, LG Soll, AR Tapper, PD Gardner |
Frontiers in physiology | 2013 |
Ketanserin improves cardiac performance after myocardial infarction in spontaneously hypertensive rats partially through restoration of baroreflex function
J Yu, E Zhang, A Liu, J Liu, G Cai, D Su |
Acta Pharmacologica Sinica | 2013 |
Pathogenesis of Abdominal Aortic Aneurysms: Role of Nicotine and Nicotinic Acetylcholine Receptors
ZZ Li, QY Dai |
Mediators of Inflammation | 2012 |
Nicotine exposure and the progression of chronic kidney disease: role of the α7-nicotinic acetylcholine receptor
G Rezonzew, P Chumley, W Feng, P Hua, GP Siegal, EA Jaimes |
American journal of physiology. Renal physiology | 2012 |
Genetics of peripheral artery disease
NJ Leeper, IJ Kullo, JP Cooke |
Circulation | 2012 |
Nicotine and Pathological Angiogenesis
J Lee, JP Cooke |
Life Sciences | 2012 |
Nicotine/Cigarette-smoke Promotes Metastasis of Pancreatic Cancer Through α7nAChR-mediated MUC4 Up-regulation
N Momi, MP Ponnusamy, S Kaur, S Rachagani, SS Kunigal, S Chellappan, MM Ouellette, SK Batra |
Oncogene | 2012 |
Feasibility of [18F]-2-Fluoro-A85380-PET Imaging of Human Vascular Nicotinic Acetylcholine Receptors In Vivo
J Bucerius, C Manka, J Schmaljohann, V Mani, D Gündisch, JH Rudd, R Bippus, FM Mottaghy, U Wüllner, ZA Fayad, HJ Biersack |
JACC: Cardiovascular Imaging | 2012 |
THE EFFECT OF NICOTINE ON ANTI–VASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY IN A MOUSE MODEL OF NEOVASCULAR AGE-RELATED MACULAR DEGENERATION:
SJ Davis, VV Lyzogubov, RG Tytarenko, AN Safar, NS Bora, PS Bora |
Retina | 2012 |
Ophthalmic drug discovery: novel targets and mechanisms for retinal diseases and glaucoma
K Zhang, L Zhang, RN Weinreb |
Nature Reviews Drug Discovery | 2012 |
Nicotine effects on human endothelial intercellular communication via α4β2 and α3β2 nicotinic acetylcholine receptor subtypes
N Duerrschmidt, A Hagen, C Gaertner, A Wermke, M Nowicki, K Spanel-Borowski, H Stepan, FW Mohr, S Dhein |
Naunyn-Schmiedeberg's Archives of Pharmacology | 2012 |
ID1 Facilitates the Growth and Metastasis of Non-Small Cell Lung Cancer in Response to Nicotinic Acetylcholine Receptor and Epidermal Growth Factor Receptor Signaling▿
S Pillai, W Rizwani, X Li, B Rawal, S Nair, MJ Schell, G Bepler, E Haura, D Coppola, S Chellappan |
Molecular and cellular biology | 2011 |
From Smoking to Cancers: Novel Targets to Neuronal Nicotinic Acetylcholine Receptors
CH Lee, CH Wu, YS Ho |
Journal of Oncology | 2011 |
Epigenetic effects and molecular mechanisms of tumorigenesis induced by cigarette smoke: an overview
RJ Chen, LW Chang, P Lin, YJ Wang |
Journal of Oncology | 2011 |
Nicotinic acetylcholine receptor signaling in tumor growth and metastasis
S Singh, S Pillai, S Chellappan |
Journal of Oncology | 2011 |
ARRB1-Mediated Regulation of E2F Target Genes in Nicotine-Induced Growth of Lung Tumors
P Dasgupta, W Rizwani, S Pillai, R Davis, S Banerjee, K Hug, M Lloyd, D Coppola, E Haura, SP Chellappan |
JNCI Journal of the National Cancer Institute | 2011 |
Nicotine inhibits cisplatin-induced apoptosis in NCI-H446 cells
F Zeng, YC Li, G Chen, YK Zhang, YK Wang, SQ Zhou, LN Ma, JH Zhou, YY Huang, WY Zhu, XG Liu |
Medical Oncology | 2011 |
Sensitization of epithelial growth factor receptors by nicotine exposure to promote breast cancer cell growth
T Nishioka, HS Kim, LY Luo, Y Huang, J Guo, CY Chen |
Breast Cancer Research | 2011 |
The parasympathetic nervous system in the quest for stroke therapeutics
C Cheyuo, A Jacob, R Wu, M Zhou, GF Coppa, P Wang |
Journal of Cerebral Blood Flow & Metabolism | 2011 |
Nicotine Increases the VEGF/PEDF Ratio in Retinal Pigment Epithelium: A Possible Mechanism for CNV in Passive Smokers with AMD
M Pons, ME Marin-Castaño |
Investigative ophthalmology & visual science | 2011 |
The α7-nicotinic Acetylcholine Receptor and MMP-2/-9 Pathway Mediate the Proangiogenic Effect of Nicotine in Human Retinal Endothelial Cells
AM Dom, AW Buckley, KC Brown, RD Egleton, AJ Marcelo, NA Proper, DE Weller, YH Shah, JK Lau, P Dasgupta |
Investigative ophthalmology & visual science | 2011 |
The role of nicotine in the pathogenesis of atherosclerosis
J Lee, JP Cooke |
Atherosclerosis | 2011 |
Promoter Methylation and Tissue-Specific Transcription of the α7 Nicotinic Receptor Gene, CHRNA7
A Canastar, J Logel, S Graw, J Finlay-Schultz, C Osborne, M Palionyte, C Drebing, M Plehaty, L Wilson, R Eyeson, S Leonard |
Journal of Molecular Neuroscience | 2011 |
Nicotine, Through Upregulating Pro-Survival Signaling, Cooperates with NNK to Promote Transformation
T Nishioka, J Guo, D Yamamoto, L Chen, P Huppi, CY Chen |
Journal of Cellular Biochemistry | 2010 |
Nicotine-induced survival signaling in lung cancer cells is dependent on their p53 status while its down-regulation by curcumin is independent
VT Puliyappadamba, VT Cheriyan, AK Thulasidasan, SV Bava, BS Vinod, PR Prabhu, R Varghese, A Bevin, S Venugopal, RJ Anto |
Molecular Cancer | 2010 |
Nicotinic receptors on rat alveolar macrophages dampen ATP-induced increase in cytosolic calcium concentration
Z Mikulski, P Hartmann, G Jositsch, Z Zasłona, KS Lips, U Pfeil, H Kurzen, J Lohmeyer, WG Clauss, V Grau, M Fronius, W Kummer |
Respiratory Research | 2010 |
Transcriptome analysis and molecular signature of human retinal pigment epithelium
NV Strunnikova, A Maminishkis, JJ Barb, F Wang, C Zhi, Y Sergeev, W Chen, AO Edwards, D Stambolian, G Abecasis, A Swaroop, PJ Munson, SS Miller |
Human Molecular Genetics | 2010 |
Novel role of Egr-1 in nicotine-related neointimal formation
RI Vazquez-Padron, D Mateu, L Rodriguez-Menocal, Y Wei, KA Webster, SM Pham |
Cardiovascular Research | 2010 |
Cholinergic activation of hematopoietic stem cells
E Chang, EC Forsberg, J Wu, B Wang, SS Prohaska, R Allsopp, IL Weissman, JP Cooke |
Vascular medicine (London, England) | 2010 |
Nicotine worsens the severity of nephropathy in diabetic mice: implications for the progression of kidney disease in smokers
P Hua, W Feng, S Ji, L Raij, EA Jaimes |
American journal of physiology. Renal physiology | 2010 |
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd |
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology | 2009 |
The role of the Akt/mTOR pathway in tobacco carcinogen-induced lung tumorigenesis
RM Memmott, PA Dennis |
Clinical cancer research | 2009 |
Chronic exposure to nicotine impairs cholinergic angiogenesis
H Konishi, J Wu, JP Cooke |
Vascular medicine (London, England) | 2009 |
nAChRs mediate human embryonic stem cell-derived endothelial cells: proliferation, apoptosis, and angiogenesis
J Yu, NF Huang, KD Wilson, JB Velotta, M Huang, Z Li, A Lee, RC Robbins, JP Cooke, JC Wu |
PloS one | 2009 |
Cholinergic modulation of angiogenesis: role of the 7 nicotinic acetylcholine receptor
JC Wu, A Chruscinski, VA de Perez, H Singh, M Pitsiouni, M Rabinovitch, PJ Utz, JP Cooke |
Journal of Cellular Biochemistry | 2009 |
Nicotine induces cell proliferation, invasion and epithelial-mesenchymal transition in a variety of human cancer cell lines
P Dasgupta, W Rizwani, S Pillai, R Kinkade, M Kovacs, S Rastogi, S Banerjee, M Carless, E Kim, D Coppola, E Haura, S Chellappan |
International Journal of Cancer | 2009 |
Is cancer triggered by altered signalling of nicotinic acetylcholine receptors?
HM Schuller |
Nature Reviews Cancer | 2009 |
Selectivity of ABT-089 for α4β2* and α6β2* nicotinic acetylcholine receptors in brain
MJ Marks, CR Wageman, SR Grady, M Gopalakrishnan, CA Briggs |
Biochemical Pharmacology | 2009 |
Haplotype and Cell Proliferation Analyses of Candidate Lung Cancer Susceptibility Genes on Chromosome 15q24-25.1
Y Liu, P Liu, W Wen, MA James, Y Wang, JE Bailey-Wilson, CI Amos, SM Pinney, P Yang, M de Andrade, GM Petersen, JS Wiest, PR Fain, AG Schwartz, A Gazdar, C Gaba, H Rothschild, D Mandal, E Kupert, J Lee, D Seminara, J Minna, MW Anderson, M You |
Cancer research | 2009 |
Endothelial nicotinic acetylcholine receptors and angiogenesis
JP Cooke, YT Ghebremariam |
Trends in Cardiovascular Medicine | 2008 |
Mecamylamine suppresses Basal and nicotine-stimulated choroidal neovascularization
K Kiuchi, M Matsuoka, JC Wu, RL Silva, M Kengatharan, M Verghese, S Ueno, K Yokoi, NH Khu, JP Cooke, PA Campochiaro |
Investigative ophthalmology & visual science | 2008 |
Nicotine augments glomerular injury in a rat model of acute nephritis
EA Jaimes, RX Tian, MS Joshi, L Raij |
American Journal of Nephrology | 2008 |
α7 nicotinic acetylcholine receptor agonist properties of tilorone and related tricyclic analogues: α7 nAChR and tilorone analogues
CA Briggs, MR Schrimpf, DJ Anderson, EJ Gubbins, JH Grønlien, M Håkerud, H Ween, K Thorin-Hagene, J Malysz, J Li, WH Bunnelle, M Gopalakrishnan, MD Meyer |
British Journal of Pharmacology | 2008 |
Acetylcholine beyond neurons: the non-neuronal cholinergic system in humans: Non-neuronal cholinergic system in humans
I Wessler, CJ Kirkpatrick |
British Journal of Pharmacology | 2008 |
Neovascular Age-Related Macular Degeneration: Potential Therapies
AV Chappelow, PK Kaiser |
Drugs | 2008 |
Nicotine alters lung branching morphogenesis through the alpha7 nicotinic acetylcholine receptor
C Wongtrakool, S Roser-Page, HN Rivera, J Roman |
American journal of physiology. Lung cellular and molecular physiology | 2007 |
Angiogenesis and the role of the endothelial nicotinic acetylcholine receptor
JP Cooke |
Life Sciences | 2007 |
Nitrosamines as nicotinic receptor ligands
HM Schuller |
Life Sciences | 2007 |
The cholinergic system is involved in regulation of the development of the hematopoietic system
N Serobyan, S Jagannathan, I Orlovskaya, I Schraufstatter, M Skok, J Loring, S Khaldoyanidi |
Life Sciences | 2007 |
Receptor-mediated tobacco toxicity: Alterations of the NF-κB expression and activity downstream of α7 nicotinic receptor in oral keratinocytes
J Arredondo, AI Chernyavsky, DL Jolkovsky, KE Pinkerton, SA Grando |
Life Sciences | 2007 |
Early Manifestations of NNK-Induced Lung Cancer: Role of Lung Immunity in Tumor Susceptibility
S Razani-Boroujerdi, ML Sopori |
American journal of respiratory cell and molecular biology | 2007 |
Nicotine induces cell proliferation by beta-arrestin mediated activation of Src and Rb-Raf-1 pathway
Piyali Dasgupta, Shipra Rastogi, Smitha Pillai, Dalia Ordonez, Mark Morris, Eric Haura and Srikumar Chellappan |
Journal of Clinical Investigation | 2006 |
Protection of early phase hepatic ischemia-reperfusion injury by cholinergic agonists
ET Crockett, JJ Galligan, BD Uhal, J Harkema, R Roth, K Pandya |
BMC clinical pathology | 2006 |
Nicotine inhibits apoptosis induced by chemotherapeutic drugs by up-regulating XIAP and survivin
P Dasgupta, R Kinkade, B Joshi, C Decook, E Haura, S Chellappan |
Proceedings of the National Academy of Sciences | 2006 |
Nicotine upregulates the expression of P2Y12 on vascular cells and megakaryoblasts
G Shanker, JL Kontos, DM Eckman, D Wesley-Farrington, DC Sane |
Journal of Thrombosis and Thrombolysis | 2006 |
Effekte von Nikotin unter besonderer Berücksichtigung der Tumorentstehung im Kopf-Hals-Bereich
MP Semmler, O Driemel, R Staudenmaier, K Froelich, NH Kleinsasser |
Mund- Kiefer- und Gesichtschirurgie | 2006 |
Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation
RW Saeed, S Varma, T Peng-Nemeroff, B Sherry, D Balakhaneh, J Huston, KJ Tracey, Y Al-Abed, CN Metz |
Journal of Experimental Medicine | 2005 |
Das extraneuronale cholinerge System der Haut
H Kurzen |
Der Hautarzt | 2004 |
Nicotine exposure and bronchial epithelial cell nicotinic acetylcholine receptor expression in the pathogenesis of lung cancer
JD Minna |
Journal of Clinical Investigation | 2003 |
Endotoxin-Induced Changes in Human Working and Declarative Memory Associate with Cleavage of Plasma "Readthrough" Acetylcholinesterase
O Cohen, A Reichenberg, C Perry, D Ginzberg, T Pollmächer, H Soreq, R Yirmiya |
Journal of Molecular Neuroscience | 2003 |