JCI - Citations to Hypothalamic growth hormone secretagogue receptor regulates growth hormone secretion, feeding, and adiposity

Citations to this article

Hypothalamic growth hormone secretagogue receptor regulates growth hormone secretion, feeding, and adiposity

Yujin Shuto, … , Shinichi Oikawa, Ichiji Wakabayashi

Yujin Shuto, … , Shinichi Oikawa, Ichiji Wakabayashi

Published June 1, 2002
Citation Information: J Clin Invest. 2002;109(11):1429-1436. https://doi.org/10.1172/JCI13300.

View: Text | PDF

Article Endocrinology

Total citations by year

Year:	2025	2024	2023	2022	2021	2019	2018	2017	2016	2015	2014	2013	2012	2011	2010	2009	2008	2007	2006	2005	2004	2003	Total
Citations:	1	1	4	1	4	1	2	1	1	1	3	4	3	3	4	9	5	2	7	7	3	6	73

Citation information

Citations to this article (73)

Title and authors	Publication	Year
Significance of Neutrophil-to-Lymphocyte Ratio in Predicting the Efficacy of Anamorelin for Cancer Cachexia Nakazawa Y, Watanabe K, Gannichida A, Uwagawa T, Kawakubo T	Cureus	2025
Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet. Lékó AH, Gregory-Flores A, Marchette RCN, Gomez JL, Vendruscolo JCM, Repunte-Canonigo V, Choung V, Deschaine SL, Whiting KE, Jackson SN, Cornejo MP, Perello M, You ZB, Eckhaus M, Rasineni K, Janda KD, Zorman B, Sumazin P, Koob GF, Michaelides M, Sanna PP, Vendruscolo LF, Leggio L	Communications biology	2024
Exploring the underlying mechanisms of obesity and diabetes and the potential of Traditional Chinese Medicine: an overview of the literature. Chen YK, Liu TT, Teia FKF, Xie MZ	Frontiers in Endocrinology	2023
Factors associated with early discontinuation of anamorelin in patients with cancer-associated cachexia Tsukiyama I, Iwata T, Takeuchi T, Kato RI, Sakuma M, Tsukiyama S, Kato M, Ikeda Y, Ohashi W, Kubo A, Mori N	Supportive Care in Cancer	2023
Cancer cachexia: Focus on cachexia factors and inter-organ communication. Wang Y, Dong Z, An Z, Jin W	Chinese Medical Journal	2023
Soy‐fortelin: A ghrelin sensitivity‐enhancing peptide that stimulates food intake in aged mice Shimizu K, Kaneko K, Koyama D, Ohinata K	The FASEB Journal	2023
Two cases of wide QRS complex tachycardia caused by anamorelin Okidono Y, Osada J, Otsu K, Kowase S, Aoki H, Yumoto K	Journal of Cardiology Cases	2022
Neuroendocrine Response to Exogenous Ghrelin Administration, Combined With Alcohol, in Heavy-Drinking Individuals: Findings From a Randomized, Double-Blind, Placebo-Controlled Human Laboratory Study M Farokhnia, KM Abshire, A Hammer, SL Deschaine, A Saravanakumar, E Cobbina, ZB You, CL Haass-Koffler, MR Lee, F Akhlaghi, L Leggio	The International Journal of Neuropsychopharmacology	2021
Advances in Genome Editing and Application to the Generation of Genetically Modified Rat Models V Chenouard, S Remy, L Tesson, S Ménoret, LH Ouisse, Y Cherifi, I Anegon	Frontiers in Genetics	2021
Disrupting the ghrelin-growth hormone axis limits ghrelin's orexigenic but not glucoregulatory actions D Gupta, AM Patterson, S Osborne-Lawrence, AL Bookout, S Varshney, K Shankar, O Singh, NP Metzger, CP Richard, SC Wyler, JK Elmquist, JM Zigman	Molecular Metabolism	2021
Ghrelin Gene Deletion Alters Pulsatile Growth Hormone Secretion in Adult Female Mice R Hassouna, G Fernandez, N Lebrun, O Fiquet, F Roelfsema, A Labarthe, P Zizzari, C Tomasetto, J Epelbaum, O Viltart, C Chauveau, M Perello, V Tolle	Frontiers in Endocrinology	2021
Ghrelin regulation of glucose metabolism SM Gray, LC Page, J Tong	Journal of Neuroendocrinology	2019
Development and initial characterization of a novel ghrelin receptor CRISPR/Cas9 knockout wistar rat model LJ Zallar, BJ Tunstall, CT Richie, YJ Zhang, ZB You, EL Gardner, M Heilig, J Pickel, GF Koob, LF Vendruscolo, BK Harvey, L Leggio	International Journal of Obesity	2018
Transcriptome analysis of growth heterosis in pearl oyster Pinctada fucata martensii J Yang, S Luo, J Li, Z Zheng, X Du, Y Deng	FEBS Open Bio	2018
The role of ghrelin-responsive mediobasal hypothalamic neurons in mediating feeding responses to fasting BK Mani, S Osborne-Lawrence, M Mequinion, S Lawrence, L Gautron, ZB Andrews, JM Zigman	Molecular Metabolism	2017
Elevation of Fasting Ghrelin in Healthy Human Subjects Consuming a High-Salt Diet: A Novel Mechanism of Obesity? Y Zhang, F Li, FQ Liu, C Chu, Y Wang, D Wang, TS Guo, JK Wang, GC Guan, KY Ren, JJ Mu	Nutrients	2016
Ghrelin TD Müller, R Nogueiras, ML Andermann, ZB Andrews, SD Anker, J Argente, R Batterham, SC Benoit, CY Bowers, F Broglio, FF Casanueva, D D'Alessio, I Depoortere, A Geliebter, E Ghigo, PA Cole, M Cowley, DE Cummings, A Dagher, S Diano, SL Dickson, C Diéguez, R Granata, HJ Grill, K Grove, KM Habegger, K Heppner, ML Heiman, L Holsen, B Holst, A Inui, JO Jansson, H Kirchner, M Korbonits, B Laferrère, CW LeRoux, M Lopez, S Morin, M Nakazato, R Nass, D Perez-Tilve, PT Pfluger, TW Schwartz, RJ Seeley, M Sleeman, Y Sun, L Sussel, J Tong, MO Thorner, AJ der Lely, LH der Ploeg, JM Zigman, M Kojima, K Kangawa, RG Smith, T Horvath, MH Tschöp	Molecular Metabolism	2015
Short-Term Estradiol Supplementation Potentiates Low-Dose Ghrelin Action in the Presence of GHRH or Somatostatin in Older Women C Norman, N Rollene, SM Weist, JR Wigham, D Erickson, JM Miles, CY Bowers, JD Veldhuis	The Journal of clinical endocrinology and metabolism	2014
Associations of polymorphisms in GHRL, GHSR, and IGF1R genes with feed efficiency in chickens S Jin, S Chen, H Li, Y Lu, G Xu, N Yang	Molecular Biology Reports	2014
Ghrelin Modulates the fMRI BOLD Response of Homeostatic and Hedonic Brain Centers Regulating Energy Balance in the Rat M Sárvári, P Kocsis, L Deli, D Gajári, S Dávid, Z Pozsgay, N Hegedűs, K Tihanyi, Z Liposits	PloS one	2014
Neuroendocrine Profile in the Night Eating Syndrome GS Birketvedt, A Geliebter, J Florholmen, ME Gluck	Current Obesity Reports	2013
The central nervous system sites mediating the orexigenic actions of ghrelin BL Mason, Q Wang, JM Zigman	Annual Review of Physiology	2013
Differential pulsatile secretagogue control of GH secretion in healthy men C Norman, J Miles, CY Bowers, JD Veldhuis	American Journal of Physiology - Regulatory, Integrative and Comparative Physiology	2013
Obesity pharmacotherapy: current perspectives and future directions. Misra M	Current cardiology reviews	2013
Ghrelin and the central regulation of feeding and energy balance A Abizaid, TL Horvath	Indian journal of endocrinology and metabolism	2012
The role of ghrelin in reward-based eating M Perelló, JM Zigman	Biological Psychiatry	2012
Ghrelin is an orexigenic peptide and elicits anxiety-like behaviors following administration into discrete regions of the hypothalamus PJ Currie, R Khelemsky, EM Rigsbee, LM Dono, CD Coiro, CD Chapman, K Hinchcliff	Behavioural Brain Research	2012
Ghrelin mediates stress-induced food reward behavior in mice Jen-Chieh Chuang, Mario Perello, Ichiro Sakata, Sherri Osborne-Lawrence, Joseph Savitt, Michael Lutter, Jeffrey Zigman	Journal of Clinical Investigation	2011
Complex regulation of GH autofeedback under dual-peptide drive: studies under a pharmacological GH and sex steroid clamp JD Veldhuis, D Erickson, JM Miles, CY Bowers	American journal of physiology. Endocrinology and metabolism	2011
Gender, Sex-Steroid, and Secretagogue-Selective Recovery from Growth Hormone-Induced Feedback in Older Women and Men JD Veldhuis, D Erickson, J Wigham, S Weist, JM Miles, CY Bowers	The Journal of clinical endocrinology and metabolism	2011
Integrating GHS into the Ghrelin System JD Veldhuis, CY Bowers	International Journal of Peptides	2010
Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity AP Gjesing, LH Larsen, SS Torekov, IA Hainerová, R Kapur, A Johansen, A Albrechtsen, S Boj, B Holst, A Harper, SA Urhammer, K Borch-Johnsen, C Pisinger, SM Echwald, H Eiberg, A Astrup, J Lebl, J Ferrer, TW Schwartz, T Hansen, O Pedersen	PloS one	2010
Hypothalamic paraventricular 5-hydroxytryptamine inhibits the effects of ghrelin on eating and energy substrate utilization PJ Currie, CS John, ML Nicholson, CD Chapman, KE Loera	Pharmacology Biochemistry and Behavior	2010
Ghrelin: New Molecular Pathways Modulating Appetite and Adiposity R Nogueiras, LM Williams, C Dieguez	Obesity facts	2010
Relative effects of estrogen, age, and visceral fat on pulsatile growth hormone secretion in healthy women JD Veldhuis, SB Hudson, D Erickson, JN Bailey, GA Reynolds, CY Bowers	American journal of physiology. Endocrinology and metabolism	2009
Determinants of GH-releasing hormone and GH-releasing peptide synergy in men JD Veldhuis, CY Bowers	American journal of physiology. Endocrinology and metabolism	2009
Novel Relationships of Age, Visceral Adiposity, Insulin-Like Growth Factor (IGF)-I and IGF Binding Protein Concentrations to Growth Hormone (GH) Releasing-Hormone and GH Releasing-Peptide Efficacies in Men during Experimental Hypogonadal Clamp JD Veldhuis, DM Keenan, JN Bailey, AM Adeniji, JM Miles, CY Bowers	The Journal of clinical endocrinology and metabolism	2009
Pre- versus postmenopausal age, estradiol, and peptide-secretagogue type determine pulsatile growth hormone secretion in healthy women: studies using submaximal agonist drive and an estrogen clamp SB Hudson, DR Schroeder, JN Bailey, KL Mielke, D Erickson, JM Miles, CY Bowers, JD Veldhuis	The Journal of clinical endocrinology and metabolism	2009
Ghrelin in central neurons F Ferrini, C Salio, L Lossi, A Merighi	Current neuropharmacology	2009
Associations of GHSR gene polymorphisms with chicken growth and carcass traits M Fang, Q Nie, C Luo, D Zhang, X Zhang	Molecular Biology Reports	2009
Fasting and postprandial plasma ghrelin levels are decreased in patients with liver failure previous to liver transplantation MT Diz-Lois, J Garcia-Buela, F Suarez, S Sangiao-Alvarellos, O Vidal, F Cordido	Endocrine	2009
Aromatase and 5α-Reductase Inhibition during an Exogenous Testosterone Clamp Unveils Selective Sex Steroid Modulation of Somatostatin and Growth Hormone Secretagogue Actions in Healthy Older Men JD Veldhuis, KL Mielke, M Cosma, C Soares-Welch, R Paulo, JM Miles, CY Bowers	The Journal of clinical endocrinology and metabolism	2009
Ghrelin Induces Abdominal Obesity Via GHS-R-Dependent Lipid Retention JS Davies, P Kotokorpi, SR Eccles, SK Barnes, PF Tokarczuk, SK Allen, HS Whitworth, IA Guschina, BA Evans, A Mode, JM Zigman, T Wells	Molecular Endocrinology	2009
Estrogen Supplementation Selectively Enhances Hypothalamo-Pituitary Sensitivity to Ghrelin in Postmenopausal Women P Kok, RC Paulo, M Cosma, KL Mielke, JM Miles, CY Bowers, JD Veldhuis	The Journal of clinical endocrinology and metabolism	2008
Estrogen elevates the peak overnight production rate of acylated ghrelin RC Paulo, R Brundage, M Cosma, KL Mielke, CY Bowers, JD Veldhuis	The Journal of clinical endocrinology and metabolism	2008
Aging and hormones of the hypothalamo-pituitary axis: gonadotropic axis in men and somatotropic axes in men and women JD Veldhuis	Ageing Research Reviews	2008
Feeding behavior during long-term hexarelin administration in young and old rats E Bresciani, N Pitsikas, L Tamiazzo, M Luoni, I Bulgarelli, D Cocchi, V Locatelli, A Torsello	Journal of Endocrinological Investigation	2008
Twenty-Four Hour Continuous Ghrelin Infusion Augments Physiologically Pulsatile, Nycthemeral, and Entropic (Feedback-Regulated) Modes of Growth Hormone Secretion JD Veldhuis, GA Reynolds, A Iranmanesh, CY Bowers	The Journal of clinical endocrinology and metabolism	2008
Pituitary and/or peripheral estrogen-receptor alpha regulates follicle-stimulating hormone secretion, whereas central estrogenic pathways direct growth hormone and prolactin secretion in postmenopausal women M Cosma, J Bailey, JM Miles, CY Bowers, JD Veldhuis	The Journal of clinical endocrinology and metabolism	2007
Gonadal status and body mass index jointly determine growth hormone (GH)-releasing hormone/GH-releasing peptide synergy in healthy men RC Paulo, M Cosma, C Soares-Welch, JN Bailey, KL Mielke, JM Miles, CY Bowers, JD Veldhuis	The Journal of clinical endocrinology and metabolism	2007
Loss of constitutive activity of the growth hormone secretagogue receptor in familial short stature Jacques Pantel, Marie Legendre, Sylvie Cabrol, Latifa Hilal, Yassir Hajaji, Séverine Morisset, Sylvie Nivot, Marie-Pierre Vie-Luton, Dominique Grouselle, Marc de Kerdanet, Abdelkrim Kadiri, Jacques Epelbaum, Yves Le Bouc and Serge Amselem	Journal of Clinical Investigation	2006
Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite Alfonso Abizaid, Zhong-Wu Liu, Zane B. Andrews, Marya Shanabrough, Erzsebet Borok, John Elsworth, Robert H. Roth, Mark Sleeman, Marina Piccioto, Matthias Tschop, Xiao-Bing Gao and Tamas L. Horvath	Journal of Clinical Investigation	2006
In search of an effective obesity treatment: a shot in the dark or a shot in the arm? JM Zigman, JK Elmquist	Proceedings of the National Academy of Sciences	2006
Vaccination against weight gain EP Zorrilla, S Iwasaki, JA Moss, J Chang, J Otsuji, K Inoue, MM Meijler, KD Janda	Proceedings of the National Academy of Sciences	2006
Anti-ghrelin Spiegelmer NOX-B11 inhibits neurostimulatory and orexigenic effects of peripheral ghrelin in rats P Kobelt, S Helmling, A Stengel, B Wlotzka, V Andresen, BF Klapp, B Wiedenmann, S Klussmann, H Mönnikes	Gut	2006
Ghrelin tissue distribution: Comparison between gene and protein expression S Ghelardoni, V Carnicelli, S Frascarelli, S Ronca-Testoni, R Zucchi	Journal of Endocrinological Investigation	2006
Chronic Treatment with Either Dexfenfluramine or Sibutramine in Diet-Switched Diet-Induced Obese Mice EN Bush, R Shapiro, ME Brune, VE Knourek-Segel, BA Droz, T Fey, E Lin, PB Jacobson	Endocrine	2006
Mice Lacking Ghrelin Receptors Resist the Development of Diet-Induced Obesity Jeffrey M. Zigman, Yoshihide Nakano, Roberto Coppari, Nina Balthasar, Jacob N. Marcus, Charlotte E. Lee, Juli E. Jones, Amy E. Deysher, Amanda R. Waxman, Ryan D. White, Todd D. Williams, Jennifer L. Lachey, Randy J. Seeley, Bradford B. Lowell, Joel K. Elmquist	Journal of Clinical Investigation	2005
Determinants of Dual Secretagogue Drive of Burst-Like Growth Hormone Secretion in Premenopausal Women Studied under a Selective Estradiol Clamp D Erickson, DM Keenan, L Farhy, K Mielke, CY Bowers, JD Veldhuis	The Journal of clinical endocrinology and metabolism	2005
Complementary Secretagogue Pairs Unmask Prominent Gender-Related Contrasts in Mechanisms of Growth Hormone Pulse Renewal in Young Adults C Soares-Welch, L Farhy, KL Mielke, FH Mahmud, JM Miles, CY Bowers, JD Veldhuis	The Journal of clinical endocrinology and metabolism	2005
Loss of Gq/11 family G proteins in the nervous system causes pituitary somatotroph hypoplasia and dwarfism in mice N Wettschureck, A Moers, B Wallenwein, AF Parlow, C Maser-Gluth, S Offermanns	Molecular and cellular biology	2005
Expression of ghrelin receptor mRNA in the rat and the mouse brain JM Zigman, JE Jones, CE Lee, CB Saper, JK Elmquist	The Journal of Comparative Neurology	2005
Leptin and Ghrelin: What is the Impact on Pituitary Function? FF Casanueva, C Dieguez	Reviews in Endocrine and Metabolic Disorders	2005
The negative association between plasma ghrelin and IGF-I is modified by obesity, insulin resistance and type 2 diabetes SM Pykk, O Ukkola, H Kauma, E Kellokoski, S Hrkk, YA Kesniemi	Diabetologia	2005
Inhibition of ghrelin action in vitro and in vivo by an RNA-Spiegelmer S Helmling, C Maasch, D Eulberg, K Buchner, W Schröder, C Lange, S Vonhoff, B Wlotzka, MH Tschöp, S Rosewicz, S Klussmann	Proceedings of the National Academy of Sciences	2004
Ghrelin, Hypothalamus-Pituitary-Adrenal (HPA) Axis and Cushing's Syndrome R Giordano, A Picu, F Broglio, L Bonelli, M Baldi, R Berardelli, E Ghigo, E Arvat	Pituitary	2004
Peripheral regulation of food intake: New insights O Ukkola	Journal of Endocrinological Investigation	2004
Control of body weight: a physiologic and transgenic perspective G Frühbeck, J Gómez-Ambrosi	Diabetologia	2003
Human GH pulsatility: An ensemble property regulated by age and gender JD Veldhuis, CY Bowers	Journal of Endocrinological Investigation	2003
Sex-Steroid Modulation of Growth Hormone (GH) Secretory Control: Three-Peptide Ensemble Regulation Under Dual Feedback Restraint by GH and IGF-I JD Veldhuis, CY Bowers	Endocrine	2003
Ghrelin and the Endocrine Pancreas F Broglio, C Gottero, A Benso, F Prodam, M Volante, S Destefanis, C Gauna, G Muccioli, M Papotti, AJ van der Lely, E Ghigo	Endocrine	2003
Targeting the Ghrelin Receptor: Orally Active GHS and Cortistatin Analogs R Deghenghi, F Broglio, M Papotti, G Muccioli, E Ghigo	Endocrine	2003
Antagonism of ghrelin receptor reduces food intake and body weight gain in mice Asakawa A, Inui A, Kaga T, Katsuura G, Fujimiya M, Fujino MA, Kasuga M	Gut	2003

Advertisement