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Citations to this article

Activators of peroxisome proliferator-activated receptor gamma have depot-specific effects on human preadipocyte differentiation.
M Adams, … , V K Chatterjee, S O'Rahilly
M Adams, … , V K Chatterjee, S O'Rahilly
Published December 15, 1997
Citation Information: J Clin Invest. 1997;100(12):3149-3153. https://doi.org/10.1172/JCI119870.
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Activators of peroxisome proliferator-activated receptor gamma have depot-specific effects on human preadipocyte differentiation.

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Abstract

Research Article

Authors

M Adams, C T Montague, J B Prins, J C Holder, S A Smith, L Sanders, J E Digby, C P Sewter, M A Lazar, V K Chatterjee, S O'Rahilly

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Diabetes - Perspectives in Drug Therapy
M Schwanstecher
2011
Diabetes - Perspectives in Drug Therapy
M Schwanstecher
2011
Diabetes - Perspectives in Drug Therapy
M Schwanstecher
2011
Diabetes - Perspectives in Drug Therapy
M Schwanstecher
2011
Diabetes - Perspectives in Drug Therapy
M Schwanstecher
2011
Diabetes - Perspectives in Drug Therapy
M Schwanstecher
2011
Diabetes - Perspectives in Drug Therapy
M Schwanstecher
2011
Diabetes - Perspectives in Drug Therapy
M Schwanstecher
2011
Diabetes - Perspectives in Drug Therapy
M Schwanstecher
2011
Diabetes - Perspectives in Drug Therapy
M Schwanstecher
2011
Diabetes - Perspectives in Drug Therapy
M Schwanstecher
2011
Diabetes - Perspectives in Drug Therapy
M Schwanstecher
2011
Diabetes - Perspectives in Drug Therapy
M Schwanstecher
2011
Diabetes - Perspectives in Drug Therapy
M Schwanstecher
2011
Cannabinoid type 1 receptor mediates depot-specific effects on differentiation, inflammation and oxidative metabolism in inguinal and epididymal white adipocytes
IV Wagner, N Perwitz, M Drenckhan, H Lehnert, J Klein
Nutrition and Diabetes 2011
In vivo adipogenesis in rats measured by cell kinetics in adipocytes and plastic-adherent stroma-vascular cells in response to high-fat diet and thiazolidinedione
YD Tchoukalova, M Fitch, PM Rogers, JD Covington, TM Henagan, J Ye, MK Hellerstein, E Ravussin
Diabetes 2011
Oxidative Stress and Disease
I Paur, M Carlsen, B Halvorsen, R Blomhoff
Herbal Medicine 2011
Type 2 Iodothyronine Deiodinase Is Expressed in Human Preadipocytes
E Nomura, N Toyoda, A Harada, K Nishimura, C Ukita, S Morimoto, A Kosaki, T Iwasaka, M Nishikawa
Thyroid 2011
The antihyperglycemic effect of curcumin in high fat diet fed rats. Role of TNF-α and free fatty acids
MA El-Moselhy, A Taye, SS Sharkawi, SF El-Sisi, AF Ahmed
Food and Chemical Toxicology 2011
Fat redistribution preferentially reflects the anti-inflammatory benefits of pioglitazone treatment
JH Moon, HJ Kim, SK Kim, ES Kang, BW Lee, CW Ahn, HC Lee, BS Cha
Metabolism 2011
Diabetes mellitus: new drugs for a new epidemic
G Nicholson, GM Hall
British Journal of Anaesthesia 2011
Determination of a peroxisome proliferator-activated receptor γ agonist, 1-(trans-methylimino-N-oxy)-6-(2-morpholinoethoxy-3-phenyl-1H-indene-2-carboxylic acid ethyl ester (KR-62980) in rat plasma by liquid chromatography–tandem mass spectrometry
MS Kim, JS Song, H Roh, JS Park, JH Ahn, SH Ahn, MA Bae
Journal of Pharmaceutical and Biomedical Analysis 2011
Annual Reports in Medicinal Chemistry
JJ Liu, TW Lee
Annual Reports in Medicinal Chemistry Volume 46 2011
Stimulation of Glucose Uptake and Improvement of Insulin Resistance by Aromadendrin
WY Zhang, JJ Lee, IS Kim, Y Kim, CS Myung
Pharmacology 2011
Management of the metabolic effects of HIV and HIV drugs
TT Brown, MJ Glesby
Nature reviews. Endocrinology 2011
Metabolic syndrome: is the preadipocyte to blame?* : Commentary
A Rees
Clinical Endocrinology 2011
Dose-independent pharmacokinetics of a new peroxisome proliferator-activated receptor-γ agonist, KR-62980, in Sprague-Dawley rats and ICR mice
JS Park, MS Kim, JS Song, SH Choi, BH Lee, J Woo, JH Ahn, MA Bae, SH Ahn
Archives of Pharmacal Research 2011
Aging and Adipose Tissue
R Florido, T Tchkonia, JL Kirkland
Handbook of the Biology of Aging 2011
Proteomic characterization of adipose tissue constituents, a necessary step for understanding adipose tissue complexity
JR Peinado, M Pardo, O la Rosa, MM Malagón
PROTEOMICS 2011
Williams Textbook of Endocrinology
DW Cooke, SA Divall, S Radovick
Williams Textbook of Endocrinology 2011
The Actions of PPARγ Agonists on the Various Target Organs
JG Kang, CY Park
The Korean Journal of Obesity 2011
Fetal programming of adipose tissue: effects of intrauterine growth restriction and maternal obesity/high-fat diet
M Desai, MG Ross
Seminars in reproductive medicine 2011
Fetal Programming of Adipose Tissue: Effects of IUGR and Maternal Obesity/High Fat Diet
M Desai, MG Ross
Seminars in reproductive medicine 2011
Mast cells function as an alternative modulator of adipogenesis through 15-deoxy-delta-12, 14-prostaglandin J 2
A Tanaka, Y Nomura, A Matsuda, K Ohmori, H Matsuda
American journal of physiology. Cell physiology 2011
Endocrine Disruptors and Puberty
E Diamanti-Kandarakis, AC Gore
2011
Smith and Nesi’s Ophthalmic Plastic and Reconstructive Surgery
EH Black, FA Nesi, CJ Calvano, GJ Gladstone, MR Levine
2011
Sex dimorphic actions of rosiglitazone in generalised peroxisome proliferator-activated receptor-gamma (PPAR-gamma)-deficient mice
SZ Duan, MG Usher, EL 4th, DS Milstone, FC 3rd, RM Mortensen
Diabetologia 2010
Utility of transplantation in studying adipocyte biogenesis and function
Y Zhang
Molecular and Cellular Endocrinology 2010
Coordinate Transcriptomic and Metabolomic Effects of the Insulin Sensitizer Rosiglitazone on Fundamental Metabolic Pathways in Liver, Soleus Muscle, and Adipose Tissue in Diabetic db/db Mice
SL Bouter, M Rodriguez, N Guigal-Stephan, S Courtade-Gaïani, L Xuereb, C Montrion, V Croixmarie, T Umbdenstock, C Boursier-Neyret, M Lonchampt, M Brun, C Dacquet, A Ktorza, BP Lockhart, JP Galizzi
PPAR Research 2010
Immunopathogenesis of thyroid eye disease: emerging paradigms
VM Naik, MN Naik, RA Goldberg, TJ Smith, RS Douglas
Survey of Ophthalmology 2010
Coronary Heart Disease and Body Fat Distribution
D Canoy
Current Atherosclerosis Reports 2010
The many facets of PPARgamma: novel insights for the skeleton
M Kawai, KM Sousa, OA MacDougald, CJ Rosen
American journal of physiology. Endocrinology and metabolism 2010
The silencing mediator of retinoid and thyroid hormone receptors (SMRT) regulates adipose tissue accumulation and adipocyte insulin sensitivity in vivo
MM Sutanto, KK Ferguson, H Sakuma, H Ye, MJ Brady, RN Cohen
The Journal of biological chemistry 2010
Burger's Medicinal Chemistry and Drug Discovery
S Bruno, L Ronda, S Faggiano, S Bettati, A Mozzarelli
Burger's Medicinal Chemistry and Drug Discovery 2010
Adipose Depots Possess Unique Developmental Gene Signatures
Y Yamamoto, S Gesta, KY Lee, TT Tran, P Saadatirad, CR Kahn
Obesity 2010
Characteristics of Proliferation and Differentiation-Dependent C/EBP, PPARγ and Leptin Gene Expression Patterns Intrinsic to Bovine Intramuscular, Perirenal and Subcutaneous Preadipocytes
M Yamamoto, Y Taniguchi, K Kano, T Yamada
Journal of Animal and Veterinary Advances 2010
Series in Cosmetic and Laser Therapy
NE Rogers, MR Avram
Hair Transplantation 2010
Discovery and development of selective PPARγ modulators as safe and effective antidiabetic agents
LS Doshi, MK Brahma, UA Bahirat, AV Dixit, KV Nemmani
Expert Opinion on Investigational Drugs 2010
Selective effects of PPARγ agonists and antagonists on human pre-adipocyte differentiation
C Leyvraz, M Suter, C Verdumo, JM Calmes, A Paroz, C Darimont, RC Gaillard, FP Pralong, V Giusti
Diabetes, Obesity and Metabolism 2010
Obesity and the development of type 2 diabetes: the effects of fatty tissue inflammation
DP Schuster
Diabetes, metabolic syndrome and obesity : targets and therapy 2010
Site-specific modulation of white adipose tissue lipid metabolism by oleoyl-estrone and/or rosiglitazone in overweight rats
R Ferrer-Lorente, C Cabot, JA Fernández-López, M Alemany
Naunyn-Schmiedeberg's Archives of Pharmacology 2010
The HIV-1/HAART associated metabolic syndrome – Novel adipokines, molecular associations and therapeutic implications
S Tsiodras, A Perelas, C Wanke, CS Mantzoros
Journal of Infection 2010
Mannose-binding dietary lectins induce adipogenic differentiation of the marrow-derived mesenchymal cells via an active insulin-like signaling mechanism
M Bajaj, A Hinge, LS Limaye, RK Gupta, A Surolia, VP Kale
Glycobiology 2010
PPARγ regulates LIF-induced growth and self-renewal of mouse ES cells through Tyk2-Stat3 pathway
C Mo, W Chearwae, JJ Bright
Cellular Signalling 2010
Hereditary ovarian cancers: from BRCA mutations to clinical management. A modern appraisal
A Tinelli, A Malvasi, G Leo, D Vergara, M Pisanò, M Ciccarese, VE Chiuri, V Lorusso
Cancer and Metastasis Reviews 2010
Mechanisms of adipose tissue redistribution with rosiglitazone treatment in various adipose depots
JG Kang, CY Park, SH Ihm, HJ Yoo, H Park, EJ Rhee, JC Won, WY Lee, KW Oh, SW Park, SW Kim
Metabolism 2010
Suppression of adipocyte differentiation by 15-methoxypinusolidic acid through inhibition of PPARγ activity
YS Lee, SH Sung, JH Hong, ES Hwang
Archives of Pharmacal Research 2010
The stromal-vascular fraction of adipose tissue contributes to major differences between subcutaneous and visceral fat depots
JR Peinado, Y Jimenez-Gomez, MR Pulido, M Ortega-Bellido, C Diaz-Lopez, FJ Padillo, J Lopez-Miranda, R Vazquez-Martínez, MM Malagón
PROTEOMICS 2010
Rosiglitazone increases cell surface GLUT4 levels in 3T3-L1 adipocytes through an enhancement of endosomal recycling
L Martinez, M Berenguer, MC Bruce, YL Marchand-Brustel, R Govers
Biochemical Pharmacology 2010
Adipose Tissue in Health and Disease: LEFF:ADIPOSE TISSUE O-BK
LA Cassis, SB Police
Adipose Tissue in Health and Disease: LEFF:ADIPOSE TISSUE O-BK 2010
Inhibitory effect and transcriptional impact of berberine and evodiamine on human white preadipocyte differentiation
Y Hu, H Fahmy, JK Zjawiony, GE Davies
Fitoterapia 2010
The Silencing Mediator of Retinoid and Thyroid Hormone Receptors (SMRT) Regulates Adipose Tissue Accumulation and Adipocyte Insulin Sensitivity in Vivo
MM Sutanto, KK Ferguson, H Sakuma, H Ye, MJ Brady, RN Cohen
The Journal of biological chemistry 2010
The many facets of PPARγ: novel insights for the skeleton
M Kawai, KM Sousa, OA MacDougald, CJ Rosen
American journal of physiology. Endocrinology and metabolism 2010
Obesity Before Birth
RH Lustig
2010
The role of LMNA in adipose: a novel mouse model of lipodystrophy based on the Dunnigan-type familial partial lipodystrophy mutation
KM Wojtanik, K Edgemon, S Viswanadha, B Lindsey, M Haluzik, W Chen, G Poy, M Reitman, C Londos
Journal of lipid research 2009
Basic and Clinical Dermatology
N Muizzuddin, D Maes, P Giacomoni
Skin Moisturization 2009
Depot-Specific Differences in Adipogenic Progenitor Abundance and Proliferative Response to High-Fat Diet
AW Joe, L Yi, Y Even, AW Vogl, FM Rossi
Stem Cells 2009
Depot specificities of PPARγ ligand actions on lipid and glucose metabolism and their implication in PPARγ-mediated body fat redistribution
WT Festuccia, Y Deshaies
Clinical Lipidology 2009
Pioglitazone Increases the Proportion of Small Cells in Human Abdominal Subcutaneous Adipose Tissue
TM McLaughlin, T Liu, G Yee, F Abbasi, C Lamendola, GM Reaven, P Tsao, SW Cushman, A Sherman
Obesity 2009
Changes in physiology with increasing fat mass
DP Schuster
Seminars in Pediatric Surgery 2009
Regional variation in adipogenesis and IGF regulatory proteins in the fetal baboon
YD Tchoukalova, PW Nathanielsz, CA Conover, SR Smith, E Ravussin
Biochemical and Biophysical Research Communications 2009
Isohumulones, the bitter component of beer, improve hyperglycemia and decrease body fat in Japanese subjects with prediabetes
K Obara, M Mizutani, Y Hitomi, H Yajima, K Kondo
Clinical Nutrition 2009
Current Therapeutic Drugs for Type 2 Diabetes, Still Useful After 50 Years?
GM Hall, G Nicholson
Anesthesia & Analgesia 2009
Luteolin inhibits adipogenic differentiation by regulating PPARγ activation
HS Park, SH Kim, YS Kim, SY Ryu, JT Hwang, HJ Yang, GH Kim, DY Kwon, MS Kim
BioFactors 2009
Increased subcutaneous fat accumulation has a protective role against subclinical atherosclerosis in asymptomatic subjects undergoing general health screening
H Narumi, K Yoshida, N Hashimoto, I Umehara, N Funabashi, S Yoshida, I Komuro
International Journal of Cardiology 2009
Augmentation of PPARγ-TAZ interaction contributes to the anti-adipogenic activity of KR62980
H Jung, MS Lee, EJ Jang, JH Ahn, NS Kang, SE Yoo, MA Bae, JH Hong, ES Hwang
Biochemical Pharmacology 2009
PPARα signaling mediates the synergistic cytotoxicity of clioquinol and docosahexaenoic acid in human cancer cells
ER Tuller, AL Brock, H Yu, JR Lou, DM Benbrook, WQ Ding
Biochemical Pharmacology 2009
Docosahexaenoic Acid Inhibits Superoxide Dismutase 1 Gene Transcription in Human Cancer Cells: The Involvement of Peroxisome Proliferator-Activated Receptor α and Hypoxia-Inducible Factor-2α Signaling
ER Tuller, CT Beavers, JR Lou, MA Ihnat, DM Benbrook, WQ Ding
Molecular pharmacology 2009
PPAR-gamma in the endothelium regulates metabolic responses to high fat diet
Takeshi Kanda, Jonathan D. Brown, Gabriela Orasanu, Silke Vogel, Juliano Sartoretto, Thomas Michel, Jorge Plutzky
Journal of Clinical Investigation 2008
It's not how fat you are, it's what you do with it that counts
S Virtue, A Vidal-Puig
PLoS Biology 2008
Distribution of body fat and risk of coronary heart disease in men and women
D Canoy
Current Opinion in Cardiology 2008
Role of Gender and Anatomical Region on Induction of Osteogenic Differentiation of Human Adipose-derived Stem Cells
AE Aksu, JP Rubin, JR Dudas, KG Marra
Annals of Plastic Surgery 2008
Regional Anatomic and Age Effects on Cell Function of Human Adipose-Derived Stem Cells
BM Schipper, KG Marra, W Zhang, AD Donnenberg, JP Rubin
Annals of Plastic Surgery 2008
Islet-1: A Potentially Important Role for an Islet Cell Gene in Visceral Fat
H Li, LK Heilbronn, D Hu, AM Poynten, MA Blackburn, DP Shirkhedkar, WH Kaplan, AD Kriketos, J Ye, DJ Chisholm
Obesity 2008
Pleiotropic effects of thiazolidinediones
CV Rizos, EN Liberopoulos, DP Mikhailidis, MS Elisaf
Expert Opinion on Pharmacotherapy 2008
Transcriptional Control of Mesenchymal Stem Cell Differentiation
J Frith, P Genever
Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie 2008
Peroxisome proliferator-activated receptor-gamma agonists and diabetes: current evidence and future perspectives
F Chiarelli, DD Marzio
Vascular Health and Risk Management 2008
Biological specificity of visceral adipose tissue and therapeutic intervention
S Perrini, A Leonardini, L Laviola, F Giorgino
Archives Of Physiology And Biochemistry 2008
Rosiglitazone improves insulin sensitivity with increased serum leptin levels in patients with type 2 diabetes mellitus
HJ Kim, SK Kim, WS Shim, JH Lee, KY Hur, ES Kang, CW Ahn, SK Lim, HC Lee, BS Cha
Diabetes Research and Clinical Practice 2008
Pharmacogenomics of metabolic effects of rosiglitazone
O Šeda, L Šedová, O Oliyarnyk, L Kazdová, D Køenová, G Corbeil, P Hamet, J Tremblay, V Køen
Pharmacogenomics 2008
Rosiglitazone and pioglitazone similarly improve insulin sensitivity and secretion, glucose tolerance and adipocytokines in type 2 diabetic patients
Y Miyazaki, RA DeFronzo
Diabetes, Obesity and Metabolism 2008
Transcriptional Control of Mesenchymal Stem Cell Differentiation
J Frith, P Genever
Transfusion Medicine and Hemotherapy 2008
Rosiglitazone is more effective than metformin in improving fasting indexes of glucose metabolism in severely obese, non-diabetic patients
A Brunani, A Caumo, S Graci, G Castagna, G Viberti, A Liuzzi
Diabetes, Obesity and Metabolism 2008
Subcutaneous Abdominal Adipose Tissue Subcompartments: Potential Role in Rosiglitazone Effects
GE Walker, P Marzullo, B Verti, G Guzzaloni, S Maestrini, F Zurleni, A Liuzzi, AM di Blasio
Obesity 2008
Effects of the Thiazolidinedione Medications on Micro- and Macrovascular Complications in Patients with Diabetes—Update 2008
A Rohatgi, DK McGuire
Cardiovascular Drugs and Therapy 2008
Effects of rosiglitazone on body fat distribution and insulin sensitivity in Korean type 2 diabetes mellitus patients
YC Hwang, EY Lee, WJ Lee, BS Cha, KH Yoon, KS Park, MK Lee
Metabolism 2008
Adipocyte volumes and levels of adipokines in diabetes and obesity
D Gokalp, M Bahceci, S Ozmen, S Arikan, A Tuzcu, R Danıs
Diabetes and Metabolic Syndrome Clinical Research and Reviews 2008
Abdominal Obesity and the Endocannabinoid System: From Basic Aspects to Clinical Management of Related Cardiometabolic Risk
D Huffman, N Barzilai
Abdominal Obesity and the Endocannabinoid System: From Basic Aspects to Clinical Management of Related Cardiometabolic Risk 2008
How safe is the use of thiazolidinediones in clinical practice?
CV Rizos, M Elisaf, DP Mikhailidis, EN Liberopoulos
Expert Opinion on Drug Safety 2008
Peroxisome Proliferator-Activated Receptor γ as a Novel Therapeutic Target in Asthma
SJ Park, YC Lee
Journal of Asthma 2008
Optimization of in vitro conditions for bovine subcutaneous and intramuscular preadipocyte differentiation1
AC Grant, G Ortiz-Colòn, ME Doumit, DD Buskirk
Journal of animal science 2008
Differentiation of bovine intramuscular and subcutaneous stromal-vascular cells exposed to dexamethasone and troglitazone1
AC Grant, G Ortiz-Colón, ME Doumit, RJ Tempelman, DD Buskirk
Journal of animal science 2008
'Striking the Right Balance' in Targeting PPARgamma in the Metabolic Syndrome: Novel Insights from Human Genetic Studies
M Gurnell
PPAR Research 2007
Vascular Peptide Endothelin-1 Links Fat Accumulation With Alterations of Visceral Adipocyte Lipolysis
V Harmelen, A Eriksson, G Astrom, K Wahlen, E Naslund, F Karpe, K Frayn, T Olsson, J Andersson, M Ryden, P Arner
Diabetes 2007
Aging in adipocytes: potential impact of inherent, depot-specific mechanisms
MJ Cartwright, T Tchkonia, JL Kirkland
Experimental Gerontology 2007
Effect of PPARalpha activation of macrophages on the secretion of inflammatory cytokines in cultured adipocytes
K Murakami, H Bujo, H Unoki, Y Saito
European Journal of Pharmacology 2007
Adipose tissue distribution and risk of metabolic disease: does thiazolidinedione-induced adipose tissue redistribution provide a clue to the answer?
X Yang, U Smith
Diabetologia 2007
The importance of free fatty acids in the development of Type�2 diabetes
JP Wilding
Diabetic Medicine 2007
Fat Tissue
SM Niemel??, S Miettinen, Y Konttinen, T Waris, M Kellom??ki, NA Ashammakhi, T Ylikomi
Journal of Craniofacial Surgery 2007
COX-2 and SCD, Markers of Inflammation and Adipogenesis, Are Related to Disease Activity in Graves' Ophthalmopathy
T Vondrichova, A Capretz, H Parikh, C Frenander, P Åsman, M Åberg, L Groop, B Hallengren, M Lantz
Thyroid 2007
Pathogenesis of Graves' Ophthalmopathy: The Role of Autoantibodies
TK Khoo, RS Bahn
Thyroid 2007
Depot-specific regulation of perilipin by rosiglitazone in a diabetic animal model
HJ Kim, TW Jung, ES Kang, DJ Kim, CW Ahn, KW Lee, HC Lee, BS Cha
Metabolism 2007
Weight gain in type 2 diabetes mellitus
AN Jacob, K Salinas, B Adams-Huet, P Raskin
Diabetes, Obesity and Metabolism 2007
PPARs and the Placenta
T Fournier, V Tsatsaris, K Handschuh, D Evain-Brion
Placenta 2007
Reduced Adiposity in ob/ob Mice following Total Body Irradiation and Bone Marrow Transplantation*
V Ablamunits, SP Weisberg, JE Lemieux, TP Combs, S Klebanov
Obesity 2007
Effects of pioglitazone and metformin on intracellular lipid content in liver and skeletal muscle of individuals with type 2 diabetes mellitus
T Teranishi, T Ohara, K Maeda, M Zenibayashi, K Kouyama, Y Hirota, H Kawamitsu, M Fujii, K Sugimura, M Kasuga
Metabolism 2007
Antidiabetic medications in overweight/obese patients with type 2 diabetes: drawbacks of current drugs and potential advantages of incretin-based treatment on body weight
E Bonora
International Journal of Clinical Practice 2007
Hypertrophy and hyperplasia of abdominal adipose tissues in women
R Drolet, C Richard, AD Sniderman, J Mailloux, M Fortier, C Huot, C Rhéaume, A Tchernof
International Journal of Obesity 2007
Effects of pioglitazone on proliferation and differentiation of human preadipocytes
J Zhou, M Ge, Y Wang, H Wu, J Shen, X Ma
Journal of Nanjing Medical University 2007
Subcutaneous fat in normal and diseased states
MM Avram, AS Avram, WD James
Journal of the American Academy of Dermatology 2007
Hipertensión arterial y dislipemia asociadas a diabetes mellitus. Papel de los PPAR. Enfoque terapéutico
V Bertomeu-González, DN Pernas, VB Martínez
Revista Española de Cardiología Suplementos 2007
The increase in abdominal subcutaneous fat depot is an independent factor to determine the glycemic control after rosiglitazone treatment
SK Kim, KY Hur, HJ Kim, WS Shim, CW Ahn, SW Park, YW Cho, SK Lim, HC Lee, BS Cha
European Journal of Endocrinology 2007
Type 2 Diabetes: Principles and Practice, Second Edition
L Adams
Type 2 Diabetes: Principles and Practice, Second Edition 2007
Characterization of ScAP-23, a new cell line from murine subcutaneous adipose tissue, identifies genes for the molecular definition of preadipocytes
JY Kim, Y Wu, CM Smas
Physiological genomics 2007
Changes in liver PPARα mRNA expression in response to two levels of high-safflower-oil diets correlate with changes in adiposity and serum leptin in rats and mice
SC Hsu, C Huang
The Journal of Nutritional Biochemistry 2007
Pharmacotherapy of Diabetes: New Developments
CE Mogensen
2007
A Novel Inhibitory Protein in Adipose Tissue, the Aldo-Keto Reductase AKR1B7: Its Role in Adipogenesis
J Tirard, J Gout, AM Lefrançois-Martinez, A Martinez, M Begeot, D Naville
Endocrinology 2007
Thiazolidinediones and their Fluid-Related Adverse Effects: Facts, Fiction and Putative Management Strategies
J Karalliedde, RE Buckingham
Drug Safety 2007
Identification of depot-specific human fat cell progenitors through distinct expression profiles and developmental gene patterns
T Tchkonia, M Lenburg, T Thomou, N Giorgadze, G Frampton, T Pirtskhalava, A Cartwright, M Cartwright, J Flanagan, I Karagiannides, N Gerry, RA Forse, Y Tchoukalova, MD Jensen, C Pothoulakis, JL Kirkland
American journal of physiology. Endocrinology and metabolism 2006
Peroxisome Proliferator-Activated Receptor γ and Adipose Tissue—Understanding Obesity-Related Changes in Regulation of Lipid and Glucose Metabolism
AM Sharma, B Staels
The Journal of clinical endocrinology and metabolism 2006
Rosiglitazone inhibits mouse liver regeneration
YP Turmelle, O Shikapwashya, S Tu, PW Hruz, Q Yan, DA Rudnick
The FASEB Journal 2006
Recombinant Methionyl Human Leptin Therapy in Replacement Doses Improves Insulin Resistance and Metabolic Profile in Patients with Lipoatrophy and Metabolic Syndrome Induced by the Highly Active Antiretroviral Therapy
JH Lee, JL Chan, E Sourlas, V Raptopoulos, CS Mantzoros
The Journal of clinical endocrinology and metabolism 2006
PPARγ and human metabolic disease
RK Semple, VK Chatterjee, S O'Rahilly
Journal of Clinical Investigation 2006
Macrophage-conditioned medium inhibits the differentiation of 3T3-L1 and human abdominal preadipocytes
VA Constant, A Gagnon, A Landry, A Sorisky
Diabetologia 2006
Fat Depot-Specific Characteristics Are Retained in Strains Derived From Single Human Preadipocytes
T Tchkonia, N Giorgadze, T Pirtskhalava, T Thomou, M DePonte, A Koo, RA Forse, D Chinnappan, C Martin-Ruiz, T Zglinicki, JL Kirkland
Diabetes 2006
Mechanisms of the Depot Specificity of Peroxisome Proliferator-Activated Receptor   Action on Adipose Tissue Metabolism
M Laplante, WT Festuccia, G Soucy, Y Gelinas, J Lalonde, JP Berger, Y Deshaies
Diabetes 2006
Insulin signalling in human adipose tissue
L Laviola, S Perrini, A Cignarelli, F Giorgino
Archives Of Physiology And Biochemistry 2006
Insulin Resistance and PPARγ
BS Cha, SE Park
The Journal of Korean Diabetes Association 2006
Evidence for a role of developmental genes in the origin of obesity and body fat distribution
S Gesta, M Blüher, Y Yamamoto, AW Norris, J Berndt, S Kralisch, J Boucher, C Lewis, CR Kahn
Proceedings of the National Academy of Sciences 2006
Pathogenesis of Graves Ophthalmopathy: Implications for Prediction, Prevention, and Treatment
JA Garrity, RS Bahn
American Journal of Ophthalmology 2006
Effect of troglitazone on tumor necrosis factor α and transforming growth factor β expression and action in human adipocyte precursor cells in primary culture
T Skurk, M Birgel, YM Lee, H Hauner
Metabolism 2006
15-Deoxy-Δ12,14-Prostaglandin J2 regulates leukemia inhibitory factor signaling through JAK-STAT pathway in mouse embryonic stem cells
J Rajasingh, JJ Bright
Experimental Cell Research 2006
Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease
ME Risner, AM Saunders, JF Altman, GC Ormandy, S Craft, IM Foley, ME Zvartau-Hind, DA Hosford, AD Roses
The Pharmacogenomics Journal 2006
Acute and 1-month effect of small-volume suction lipectomy on insulin sensitivity and cardiovascular risk
DA Davis, DM Pellowski, DA Davis, WT Donahoo
International Journal of Obesity 2006
Treatment with a thiazolidinedione increases eye protrusion in a subgroup of patients with type 2 diabetes
M Dorkhan, M Lantz, A Frid, L Groop, B Hallengren
Clinical Endocrinology 2006
Glimepiride versus pioglitazone combination therapy in subjects with type 2 diabetes inadequately controlled on metformin monotherapy: results of a randomized clinical trial
G Umpierrez, M Issa, A Vlajnic
Current Medical Research and Opinion 2006
Long-term Effect of Pioglitazone Treatment in Patients with Type 2 Diabetes
JH Moon, HJ Kim, SK Kim, WS Shim, ES Kang, Y Rhee, CW Ahn, SK Lim, KR Kim, HC Lee, BS Cha
The Journal of Korean Diabetes Association 2006
Thiazolidinediones, insulin resistance and obesity: finding a balance
J Wilding
International Journal of Clinical Practice 2006
Depot-specific prostaglandin synthesis in human adipose tissue: A novel possible mechanism of adipogenesis
M Quinkler, IJ Bujalska, JW Tomlinson, DM Smith, PM Stewart
Gene 2006
The thiazolidinedione drug troglitazone up-regulates nitric oxide synthase expression in vascular endothelial cells
K Goya, S Sumitani, M Otsuki, X Xu, H Yamamoto, S Kurebayashi, H Saito, H Kouhara, S Kasayama
Journal of Diabetes and its Complications 2006
The Emerging Functions of UCP2 in Health, Disease, and Therapeutics
G Mattiasson, PG Sullivan
Antioxidants & Redox Signaling 2006
The effects of irbesartan and telmisartan on metabolic parameters and blood pressure in obese, insulin resistant, hypertensive patients
R Negro, G Formoso, H Hassan
Journal of Endocrinological Investigation 2006
Thiazolidinediones and risk for atherosclerosis: pleiotropic effects of PPARγ agonism
CB Patle, JA de Lemos, KL Wyne, DK McGuire
Diabetes & vascular disease research : official journal of the International Society of Diabetes and Vascular Disease 2006
The effects of telmisartan and amlodipine on metabolic parameters and blood pressure in type 2 diabetic, hypertensive patients
R Negro, H Hassan
Journal of Renin-Angiotensin-Aldosterone System 2006
Interleukin-6 release from human abdominal adipose cells is regulated by thyroid-stimulating hormone: effect of adipocyte differentiation and anatomic depot
TT Antunes, A Gagnon, B Chen, F Pacini, TJ Smith, A Sorisky
American journal of physiology. Endocrinology and metabolism 2006
Cardioprotective effects of rosiglitazone are associated with selective overexpression of type 2 angiotensin receptors and inhibition of p42/44 MAPK
B Molavi, J Chen, JL Mehta
American journal of physiology. Heart and circulatory physiology 2006
Characterization of the transcriptional and functional effects of fibroblast growth factor-1 on human preadipocyte differentiation
FS Newell, H Su, H Tornqvist, JP Whitehead, JB Prins, LJ Hutley
The FASEB Journal 2006
Long-Term Treatment with Lopinavir-Ritonavir Induces a Reduction in Peripheral Adipose Depots in Mice
M Prot, L Heripret, N Cardot-Leccia, C Perrin, M Aouadi, T Lavrut, R Garraffo, P Dellamonica, J Durant, YL Marchand-Brustel, B Binétruy
Antimicrobial agents and chemotherapy 2006
CYP450, COX-2 and Obesity Related Renal Damage
JD Imig, X Zhao, A Dey, M Shaw
Toxicology Mechanisms and Methods 2005
Regional differences of insulin action in adipose tissue: insights from in vivo and in vitro studies
F Giorgino, L Laviola, JW Eriksson
Acta Physiologica Scandinavica 2005
Fatty acids and insulin resistance in muscle and liver
P Kovacs, M Stumvoll
Best Practice & Research Clinical Endocrinology & Metabolism 2005
Adiponectin receptor gene expression in human skeletal muscle cells is not regulated by fibrates and thiazolidinediones
S Kaltenbach, H Staiger, M Weisser, C Haas, M Stumvoll, F Machicao, HU Häring
International Journal of Obesity 2005
Evaluating the Cardiovascular Effects of the Thiazolidinediones and Their Place in the Management of Type 2 Diabetes in Relation to the Metabolic Syndrome
AJ Drexler, RW Nesto, MJ Abrahamson, G Bakris, D Bell, J Brunzell, P Dandona, J Davidson, V Fonseca, M Fowler, R Frye, T Giles, S Haffner, N Hollenberg, W Hsueh, R Law, J Plutzky, R Ratner, J Reusch, A Selwyn, J Sowers, K Wyne, LH Young
Metabolic Syndrome and Related Disorders 2005
Peroxisome proliferator-activated receptor γ and the regulation of adipocyte function: lessons from human genetic studies
M Gurnell
Best Practice & Research Clinical Endocrinology & Metabolism 2005
15d-PGJ2: The anti-inflammatory prostaglandin?
JU Scher, MH Pillinger
Clinical Immunology 2005
Rosiglitazone effects on blood pressure and metabolic parameters in nondipper diabetic patients
R Negro, T Mangieri, D Dazzi, A Pezzarossa, H Hassan
Diabetes Research and Clinical Practice 2005
Biology of Growing Animals
AW Bell, PL Greenwood, RA Ehrhardt
Biology of Growing Animals 2005
Rein et glitazones
G Deray, H Izzedine, V Launay-Vacher, C Bagnis
Annales d'Endocrinologie 2005
Données cliniques nouvelles sur les glitazones
B Guerci
Annales d'Endocrinologie 2005
Ácido linoléico conjugado e perda de peso
DM Mourão, JB Monteiro, PC Stringheta, VP Minim, CM Dias
Revista de Microbiologia 2005
Abundance of two human preadipocyte subtypes with distinct capacities for replication, adipogenesis, and apoptosis varies among fat depots
T Tchkonia, YD Tchoukalova, N Giorgadze, T Pirtskhalava, I Karagiannides, RA Forse, A Koo, M Stevenson, D Chinnappan, A Cartwright, MD Jensen, JL Kirkland
American journal of physiology. Endocrinology and metabolism 2005
Predictors of improved glycaemic control with rosiglitazone therapy in type 2 diabetic patients: a practical approach for the primary care physician
Y Miyazaki, ED Filippis, M Bajaj, E Wajcberg, L Glass, C Triplitt, E Cersosimo, LJ Mandarino, RA Defronzo
The British Journal of Diabetes & Vascular Disease 2005
Cancer Chemoprevention
GJ Kelloff, ET Hawk, CC Sigman
2005
Fibroblast growth factor 1: a key regulator of human adipogenesis
L Hutley, W Shurety, F Newell, R McGeary, N Pelton, J Grant, A Herington, D Cameron, J Whitehead, J Prins
Diabetes 2004
Role of a critical visceral adipose tissue threshold (CVATT) in metabolic syndrome: implications for controlling dietary carbohydrates: a review
ES Freedland
Nutrition & Metabolism 2004
Failure of fat cell proliferation, mitochondrial function and fat oxidation results in ectopic fat storage, insulin resistance and type II diabetes mellitus
L Heilbronn, SR Smith, E Ravussin
International Journal of Obesity 2004
Role of the Adipocyte, Free Fatty Acids, and Ectopic Fat in Pathogenesis of Type 2 Diabetes Mellitus: Peroxisomal Proliferator-Activated Receptor Agonists Provide a Rational Therapeutic Approach
H Bays, L Mandarino, RA DeFronzo
The Journal of clinical endocrinology and metabolism 2004
Serum adiponectin as a biomarker for in vivo PPARgamma activation and PPARgamma agonist-induced efficacy on insulin sensitization/lipid lowering in rats
B Yang, KK Brown, L Chen, KM Carrick, LG Clifton, JA McNulty, DA Winegar, JC Strum, SA Stimpson, GL Pahel
BMC pharmacology 2004
Intramyocellular lipids and insulin resistance
J Machann, H Haring, F Schick, M Stumvoll
Diabetes, Obesity and Metabolism 2004
Subcutaneous Adipocytes Can Differentiate into Bone-Forming Cellsin Vitroandin Vivo
J Justesen, SB Pedersen, K Stenderup, M Kassem
Tissue Engineering 2004
Effects of food restriction on peroxisome proliferator-activated receptor-γ and glucocorticoid receptor signaling in adipose tissues of normal rats
K Arai, T Soga, H Ohata, A Otagiri, T Shibasaki
Metabolism 2004
METABOLIC IMPROVEMENT AND ABDOMINAL FAT REDISTRIBUTION IN WERNER SYNDROME BY PIOGLITAZONE
K Yokote, S Honjo, K Kobayashi, M Fujimoto, H Kawamura, S Mori, Y Saito
Journal of the American Geriatrics Society 2004
Differential effects of PD98059 and U0126 on osteogenesis and adipogenesis
ZC Dang, CW Lowik
Journal of Cellular Biochemistry 2004
Differential effects of peroxisome proliferator activated receptor-gamma (PPARgamma) ligands in proximal tubular cells: Thiazolidinediones are partial PPARgamma agonists
RS Chana, AJ Lewington, NJ Brunskill
Kidney International 2004
Induction of Adipocyte-Like Phenotype in Human Mesenchymal Stem Cells by Hypoxia
T Fink, L Abildtrup, K Fogd, BM Abdallah, M Kassem, P Ebbesen, V Zachar
Stem Cells 2004
No effect of rosiglitazone for treatment of HIV-1 lipoatrophy: randomised, double-blind, placebo-controlled trial
A Carr, C Workman, D Carey, G Rogers, A Martin, D Baker, H Wand, M Law, K Samaras, S Emery, DA Cooper
The Lancet 2004
Thiazolidinediones
H Yki-Järvinen
New England Journal of Medicine 2004
Peroxisome proliferator-activated receptor γ: Its role in metabolic syndrome
R Pakala, P Kuchulakanti, SW Rha, E Cheneau, R Baffour, R Waksman
Cardiovascular Radiation Medicine 2004
A yeast two-hybrid technology-based system for the discovery of PPARγ agonist and antagonist
Q Chen, J Chen, T Sun, J Shen, X Shen, H Jiang
Analytical Biochemistry 2004
Computerized Determination of Adipocyte Size
T Björnheden, B Jakubowicz, M Levin, B Odén, S Edén, L Sjöström, M Lönn
Obesity research 2004
The Yellow Agouti Mutation Alters Some But Not All Responses to Diet and Exercise
S Chiu, JS Fisler, GM Espinal, PJ Havel, JS Stern, CH Warden
Obesity research 2004
The effect of pioglitazone on peroxisome proliferator-activated receptor-gamma target genes related to lipid storage in vivo
Iwona Bogacka, Hui Xie, George A Bray, Steven R Smith
Diabetes care 2004
Lipids and glucose in type 2 diabetes: what is the cause and effect?
Guenther Boden, Markku Laakso
Diabetes care 2004
Development of multiple lipomas during treatment with rosiglitazone in a patient with HIV-associated lipoatrophy:
DD Mafong, GA Lee, S Yu, P Tien, T Mauro, C Grunfeld
AIDS 2004
Characterization of differentiated subcutaneous and visceral adipose tissue from children: the influences of TNF-α and IGF-I
M Grohmann, M Sabin, J Holly, J Shield, E Crowne, C Stewart
Journal of lipid research 2004
Expression of cellular inhibitor of apoptosis protein-2 in human subcutaneous and omental adipose tissue
X Li, R Chen, S Lindquist, O Hernell
International Journal of Obesity 2004
Combined Thiazolidinedione-Insulin Therapy: Should We Be Concerned About Safety?
AJ Scheen
Drug Safety 2004
Increased adipose tissue expression of Grb14 in several models of insulin resistance
B Cariou, N Capitaine, VL Marcis, N Vega, V Béréziat, M Kergoat, M Laville, J Girard, H Vidal, AF Burnol
The FASEB Journal 2004
Modulation of circulating and adipose tissue adiponectin levels by antidiabetic therapy
SA Phillips, TP Ciaraldi, AP Kong, R Bandukwala, V Aroda, L Carter, S Baxi, SR Mudaliar, RR Henry
Diabetes 2003
International Textbook of Diabetes Mellitus
RA DeFronzo, L Mandarino, E Ferrannini
International Textbook of Diabetes Mellitus 2003
Do regional differences in adipocyte biology provide new pathophysiological insights?
M Lafontan, M Berlan
Trends in Pharmacological Sciences 2003
Rapid reversal of hepatic steatosis, and reduction of muscle triglyceride, by rosiglitazone: MRI/S studies in Zucker fatty rats
PD Hockings, KK Changani, N Saeed, DG Reid, J Birmingham, P O'Brien, J Osborne, CN Toseland, RE Buckingham
Diabetes, Obesity and Metabolism 2003
Thiazolidinediones – some recent developments
M Stumvoll
Expert Opinion on Investigational Drugs 2003
Is weight loss possible in patients treated with thiazolidinediones? Experience with a low-calorie diet
S Asnani, BC Richard, C Desouza, V Fonseca
Current Medical Research and Opinion 2003
c-Fos-driven transcriptional activation of transforming growth factor β-1: inhibition of high glucose-induced promoter activity by thiazolidinediones
C Weigert, K Brodbeck, A Bierhaus, HU Häring, ED Schleicher
Biochemical and Biophysical Research Communications 2003
Dexamethasone induced preadipocyte recruitment and expression of CCAAT/enhancing binding protein α and peroxisome proliferator activated receptor-γ proteins in porcine stromal-vascular (S-V) cell cultures obtained before and after the onset of fetal adipogenesis
GJ Hausman
General and Comparative Endocrinology 2003
Effects of rosiglitazone and linoleic acid on human preadipocyte differentiation
LJ Hutley, FM Newell, JM Joyner, SJ Suchting, AC Herington, DP Cameron, JB Prins
European Journal of Clinical Investigation 2003
Troglitazone but not rosiglitazone induces G1 cell cycle arrest and apoptosis in human and rat hepatoma cell lines
MA Bae, H Rhee, BJ Song
Toxicology Letters 2003
Apoptosis of human abdominal preadipocytes before and after differentiation into adipocytes in culture
D Papineau, AM Gagnon, A Sorisky
Metabolism 2003
Sex differences in the pharmacokinetics of pioglitazone in rats
Y Fujita, Y Yamada, M Kusama, T Yamauchi, J Kamon, T Kadowaki, T Iga
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 2003
Effect of rosiglitazone on spontaneous and clomiphene citrate–induced ovulation in women with polycystic ovary syndrome
G Ghazeeri, WH Kutteh, M Bryer-Ash, D Haas, RW Ke
Fertility and Sterility 2003
Pioglitazone Reduces Hepatic Fat Content and Augments Splanchnic Glucose Uptake in Patients With Type 2 Diabetes
M Bajaj, S Suraamornkul, T Pratipanawatr, LJ Hardies, W Pratipanawatr, L Glass, E Cersosimo, Y Miyazaki, RA DeFronzo
Diabetes 2003
Handbook of Obesity: Etiology and Pathophysiology, Second Edition
R Pasquali, V Vicennati, U Pagotto
Handbook of Obesity: Etiology and Pathophysiology, Second Edition 2003
Human Mesenchymal Stem Cells as an in Vitro Model for Human Adipogenesis
L Janderová, M McNeil, AN Murrell, RL Mynatt, SR Smith
Obesity research 2003
Effects of pioglitazone versus diet and exercise on metabolic health and fat distribution in upper body obesity
Samyah Shadid, Michael D Jensen
Diabetes care 2003
Effects of troglitazone in young first-degree relatives of patients with type 2 diabetes
Klaus Levin, Ole Hother-Nielsen, Jan Erik Henriksen, Henning Beck-Nielsen
Diabetes care 2003
PPARgamma agonists in the treatment of type II diabetes: is increased fatness commensurate with long-term efficacy?
TM Larsen, S Toubro, A Astrup
International Journal of Obesity 2003
Expression of the thermogenic nuclear hormone receptor coactivator PGC-1α is reduced in the adipose tissue of morbidly obese subjects
RK Semple, VC Crowley, CP Sewter, M Laudes, C Christodoulides, RV Considine, A Vidal-Puig, S O'Rahilly
International Journal of Obesity 2003
Greater replication and differentiation of preadipocytes in inherited corticosteroid-binding globulin deficiency
JM Joyner, LJ Hutley, AW Bachmann, DJ Torpy, JB Prins
American journal of physiology. Endocrinology and metabolism 2003
PPARα/γ ragaglitazar eliminates fatty liver and enhances insulin action in fat-fed rats in the absence of hepatomegaly
JM Ye, MA Iglesias, DG Watson, B Ellis, L Wood, PB Jensen, RV Sørensen, PJ Larsen, GJ Cooney, K Wassermann, EW Kraegen
American journal of physiology. Endocrinology and metabolism 2003
Establishment of a human preadipose cell line, HPB-AML-I: Refractory to PPAR?-mediated adipogenic stimulation
I Torii, S Morikawa, A Nakano, K Morikawa
Journal of Cellular Physiology 2003
Body Habitus Changes Related to Lipodystrophy
F Sattler
Clinical Infectious Diseases 2003
CASE REPORT: Combined Treatment with Ursodeoxycholic Acid and Pioglitazone in a Patient with Nash Associated with Type 2 Diabetes and Psoriasis
S Itoh, A Kanazuka, T Akimoto
Digestive Diseases and Sciences 2003
Fat depot origin affects adipogenesis in primary cultured and cloned human preadipocytes
T Tchkonia, N Giorgadze, T Pirtskhalava, Y Tchoukalova, I Karagiannides, RA Forse, M DePonte, M Stevenson, W Guo, J Han, G Waloga, TL Lash, MD Jensen, JL Kirkland
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 2002
Stimulation of proximal tubular cell apoptosis by albumin-bound fatty acids mediated by peroxisome proliferator activated receptor-gamma
M Arici, R Chana, A Lewington, J Brown, NJ Brunskill
Journal of the American Society of Nephrology : JASN 2002
Emerging paradigms for understanding fatness and diabetes risk
SR Smith, E Ravussin
Current Diabetes Reports 2002
Rosiglitazone: A Review of its Use in the Management of Type 2 Diabetes Mellitus
AJ Wagstaff, KL Goa
Drugs 2002
PPAR agonists in health and disease: a pathophysiologic and clinical overview
S Mudaliar, RR Henry
Current Opinion in Endocrinology & Diabetes 2002
Increased Fat Intake, Impaired Fat Oxidation, and Failure of Fat Cell Proliferation Result in Ectopic Fat Storage, Insulin Resistance, and Type 2 Diabetes Mellitus
E Ravussin, SR Smith
Annals of the New York Academy of Sciences 2002
Adipose depot-specific effects of PPARgamma agonists: a consequence of differential expression of PPARgamma in adipose tissue depots?
CT Montague
Diabetes, Obesity and Metabolism 2002
Stimulation of Peroxisome Proliferator-Activated Receptors α and γ Blocks HIV-1 Replication and TNFα Production in Acutely Infected Primary Blood Cells, Chronically Infected U1 Cells, and Alveolar Macrophages From HIV-Infected Subjects
PR Skolnik, MF Rabbi, JM Mathys, AS Greenberg
JAIDS Journal of Acquired Immune Deficiency Syndromes 2002
PPARgamma and the thiazolidinediones: molecular basis for a treatment of 'Syndrome X'?
C Sewter, A Vidal-Puig
Diabetes, Obesity and Metabolism 2002
The role of peroxisome proliferator-activated receptor gamma in diabetes and obesity
FS Celi, AR Shuldiner
Current Diabetes Reports 2002
Thiazolidinediones in the treatment of Type 2 diabetes
AS Greenberg, AG Pittas
Expert Opinion on Pharmacotherapy 2002
The mode of action of thiazolidinediones
H Hauner
Diabetes/Metabolism Research and Reviews 2002
A treatment for Mr WP: thiazolidinediones after troglitazone
CT Montague
Diabetic Medicine 2002
Human B Lymphocytes and B Lymphomas Express PPAR-γ and Are Killed by PPAR-γ Agonists
J Padilla, E Leung, RP Phipps
Clinical Immunology 2002
Differentiating members of the thiazolidinedione class: a focus on safety
HE Lebovitz
Diabetes/Metabolism Research and Reviews 2002
Mesenchymal Cell Culture
AJ Katz
2002
New insights in the transcriptional activity and coregulator molecules in the arterial wall
F Nigris, LO Lerman, C Napoli
International Journal of Cardiology 2002
Increased lipolysis and decreased leptin production by human omental as compared with subcutaneous preadipocytes
V Harmelen, A Dicker, M Rydén, H Hauner, F Lönnqvist, E Näslund, P Arner
Diabetes 2002
Effect of Rosiglitazone on Insulin Sensitivity and Body Composition in Type 2 Diabetic Patients: The online title of this article has been corrected and is different from the printed version
DG Carey, GJ Cowin, GJ Galloway, NP Jones, JC Richards, N Biswas, DM Doddrell
Obesity research 2002
Regulation of Glucose Transport and Insulin Signaling by Troglitazone or Metformin in Adipose Tissue of Type 2 Diabetic Subjects
TP Ciaraldi, AP Kong, NV Chu, DD Kim, S Baxi, M Loviscach, R Plodkowski, R Reitz, M Caulfield, S Mudaliar, RR Henry
Diabetes 2002
Rosiglitazone but Not Metformin Enhances Insulin- and Exercise-Stimulated Skeletal Muscle Glucose Uptake in Patients With Newly Diagnosed Type 2 Diabetes
K Hallsten, KA Virtanen, F Lonnqvist, H Sipila, A Oksanen, T Viljanen, T Ronnemaa, J Viikari, J Knuuti, P Nuutila
Diabetes 2002
The Peroxisome Proliferator-Activated Receptor- 2 Pro12Ala Polymorphism
M Stumvoll, H Haring
Diabetes 2002
Regional Differences in the Response of Human Pre-Adipocytes to PPAR  and RXR  Agonists
CP Sewter, F Blows, A Vidal-Puig, S O'Rahilly
Diabetes 2002
Dose-response effect of pioglitazone on insulin sensitivity and insulin secretion in type 2 diabetes
Yoshinori Miyazaki, Masafumi Matsuda, Ralph A DeFronzo
Diabetes care 2002
Evaluation of liver function in type 2 diabetic patients during clinical trials: evidence that rosiglitazone does not cause hepatic dysfunction
Harold E Lebovitz, Margaret Kreider, Martin I Freed
Diabetes care 2002
The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes
Adam B. Mayerson, Ripudaman S. Hundal, Sylvie Dufour, Vincent Lebon, Douglas Befroy, Gary W. Cline, Staffan Enocksson, Silvio E. Inzucchi, Gerald I. Shulman, Kitt F. Petersen
Diabetes 2002
Peroxisome Proliferator-activated Receptor γ (PPARγ) as a Molecular Target for the Soy Phytoestrogen Genistein
ZC Dang, V Audinot, SE Papapoulos, JA Boutin, CW Löwik
The Journal of biological chemistry 2002
Natural ligands of PPARγ:
O Nosjean, JA Boutin
Cellular Signalling 2002
Ligand activation of peroxisome proliferator-activated receptor γ induces apoptosis of leukemia cells by down-regulating the c-myc gene expression via blockade of the Tcf-4 activity
N Yamakawa-Karakida, K Sugita, T Inukai, K Goi, M Nakamura, K Uno, H Sato, K Kagami, N Barker, S Nakazawa
Cell Death and Differentiation 2002
Angiotensin Blockade Prevents Type 2 Diabetes by Formation of Fat Cells
AM Sharma, J Janke, K Gorzelniak, S Engeli, FC Luft
Hypertension 2002
HIV Therapies and Atherosclerosis: Answers or Questions?
NR Madamanchi, C Patterson, MS Runge
Arteriosclerosis, thrombosis, and vascular biology 2002
Human Cell Culture
MR Koller, BO Palsson, JR Masters
2002
Effect of Pioglitazone on Abdominal Fat Distribution and Insulin Sensitivity in Type 2 Diabetic Patients
Y Miyazaki, A Mahankali, M Matsuda, S Mahankali, J Hardies, K Cusi, LJ Mandarino, RA DeFronzo
The Journal of clinical endocrinology and metabolism 2002
Thiazolidinediones and type 2 diabetes: new drugs for an old disease
TM O'MooreSullivan, JB Prins
The Medical Journal of Australia 2002
Differential Expression of Signal Transducers and Activators of Transcription during Human Adipogenesis
JB Harp, D Franklin, AA Vanderpuije, JM Gimble
Biochemical and Biophysical Research Communications 2001
The HIV protease inhibitor indinavir impairs sterol regulatory element-binding protein-1 intranuclear localization, inhibits preadipocyte differentiation, and induces insulin resistance
M Caron, M Auclair, C Vigouroux, M Glorian, C Forest, J Capeau
Diabetes 2001
The biology of white adipocyte proliferation
DB Hausman, M DiGirolamo, TJ Bartness, GJ Hausman, RJ Martin
Obesity Reviews 2001
Different fat depots are distinct mini-organs
T Tchkonia, I Karagiannides, RA Forse, JL Kirkland
Current Opinion in Endocrinology & Diabetes 2001
Free fatty acids - do they play a central role in type 2 diabetes?
P Arner
Diabetes, Obesity and Metabolism 2001
Insulin-sensitizing action of rosiglitazone is enhanced by preventing hyperphagia
LC Pickavance, RE Buckingham, JP Wilding
Diabetes, Obesity and Metabolism 2001
Effects of Troglitazone on Cellular Differentiation, Insulin Signaling, and Glucose Metabolism in Cultured Human Skeletal Muscle Cells
C Kausch, J Krützfeldt, A Witke, A Rettig, O Bachmann, K Rett, S Matthaei, F Machicao, HU Häring, M Stumvoll
Biochemical and Biophysical Research Communications 2001
Rosiglitazone
BH Wolffenbuttel, JP Sels, MS Huijberts
Expert Opinion on Pharmacotherapy 2001
PPARγ agonists in type 2 diabetes: how far have we come in ‘preventing the inevitable’? A review of the metabolic effects of rosiglitazone
B Zinman
Diabetes, Obesity and Metabolism 2001
Anti-retroviral therapy, insulin resistance and lipodystrophy
SK Gan, K Samaras, A Carr, D Chisholm
Diabetes, Obesity and Metabolism 2001
Changes of Pyridine Nucleotide Levels during Adipocyte Differentiation of Mouse 3T3-L1 Cells
T FUKUWATARI, M DOI, E SUGIMOTO, T KAWADA, K SHIBATA
Bioscience, Biotechnology, and Biochemistry 2001
Therapeutic modulation of transcription factor activity
JG Emery, EH Ohlstein, M Jaye
Trends in Pharmacological Sciences 2001
A Review of Rosiglitazone in Type 2 Diabetes Mellitus
AL Werner, MT Travaglini
Pharmacotherapy 2001
Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistance
CJ de Souza, M Eckhardt, K Gagen, M Dong, W Chen, D Laurent, BF Burkey
Diabetes 2001
Independent Influences of Central Fat and Skeletal Muscle Lipids on Insulin Sensitivity
SM Furler, AM Poynten, AD Kriketos, AJ Lowy, BA Ellis, EL Maclean, BG Courtenay, EW Kraegen, LV Campbell, DJ Chisholm
Obesity research 2001
Adipose depot-specific expression of cIAP2 in human preadipocytes and modulation of expression by serum factors and TNFα
CU Niesler, JB Prins, S O'Rahilly, K Siddle, CT Montague
International Journal of Obesity 2001
Improved Glycemic Control and Enhanced Insulin Sensitivity in Type 2 Diabetic Subjects Treated With Pioglitazone
Y Miyazaki, A Mahankali, M Matsuda, L Glass, S Mahankali, E Ferrannini, K Cusi, LJ Mandarino, RA DeFronzo
Diabetes care 2001
Resistin / Fizz3 Expression in Relation to Obesity and Peroxisome Proliferator-Activated Receptor-  Action in Humans
DB Savage, CP Sewter, ES Klenk, DG Segal, A Vidal-Puig, RV Considine, S O'Rahilly
Diabetes 2001
Mitochondria in the pathogenesis of lipodystrophy induced by anti-HIV antiretroviral drugs: actors or bystanders?: Challenges
A Cossarizza, C Mussini, A Viganò
BioEssays 2001
Conjugated linoleic acid (CLA) reduced abdominal adipose tissue in obese middle-aged men with signs of the metabolic syndrome: a randomised controlled trial
U Risérus, L Berglund, B Vessby
International Journal of Obesity 2001
Human adipose tissue endothelial cells promote preadipocyte proliferation
LJ Hutley, AC Herington, W Shurety, C Cheung, DA Vesey, DP Cameron, JB Prins
American journal of physiology. Endocrinology and metabolism 2001
Fat depot origin affects fatty acid handling in cultured rat and human preadipocytes
F Caserta, T Tchkonia, VN Civelek, M Prentki, NF Brown, JD McGarry, RA Forse, BE Corkey, JA Hamilton, JL Kirkland
American journal of physiology. Endocrinology and metabolism 2001
Magnitude of Peroxisome Proliferator-Activated Receptor-γ Activation is Associated With Important and Seemingly Opposite Biological Responses in Breast Cancer Cells:
CE Clay, AM Namen, G Atsumi, AJ Trimboli, AN Fonteh, KP High, FH Chilton
Journal of Investigative Medicine 2001
Estrogen Receptors in Human Preadipocytes
JM Joyner, LJ Hutley, DP Cameron
Endocrine 2001
MOLECULARREGULATION OFADIPOGENESIS
ED Rosen, BM Spiegelman
Annual Review of Cell and Developmental Biology 2000
Effects of Lipid-Related Factors on Adipocyte Differentiation of Bovine Stromal-Vascular Cells in Primary Culture
P WU, K SATO, F SUZUTA, Y HIKASA, K KAGOTA
Journal of Veterinary Medical Science 2000
Disorders of Glucose Metabolism in Patients Infected with Human Immunodeficiency Virus
MP Dubé
Clinical Infectious Diseases 2000
HIV Protease Inhibitor-Related Lipodystrophy Syndrome
A Carr
Clinical Infectious Diseases 2000
Human adipocyte proteomics - a complementary way of looking at fat
YD Halvorsen, WO Wilkison, MR Briggs
Pharmacogenomics 2000
HIV protease inhibitors block adipogenesis and increase lipolysis in vitro
JM Lenhard, ES Furfine, RG Jain, O Ittoop, LA Orband-Miller, SG Blanchard, MA Paulik, JE Weiel
Antiviral Research 2000
PPAR-γ agonists: therapeutic role in diabetes, inflammation and cancer
GJ Murphy, JC Holder
Trends in Pharmacological Sciences 2000
A Rational Approach to Drug Therapy of Type 2 Diabetes Mellitus
JM Chehade, AD Mooradian
Drugs 2000
PPAR-γ-Mediated Regulation of Normal and Malignant B Lineage Cells
J Padilla, K Kaur, SG Harris, RP Phipps
Annals of the New York Academy of Sciences 2000
Enhancing Effect of Troglitazone on Porcine Adipocyte Differentiation in Primary Culture: A Comparison with Dexamethasone
YD Tchoukalova, DB Hausman, RG Dean, GJ Hausman
Obesity 2000
Subcutaneous and Visceral Adipose Tissue: Their Relation to the Metabolic Syndrome
BL Wajchenberg
Endocrine reviews 2000
Down-regulation of orexin gene expression by severe obesity in the rats: studies in Zucker fatty and Zucker diabetic fatty rats and effects of rosiglitazone
XJ Cai, CA Lister, RE Buckingham, L Pickavance, J Wilding, JR Arch, S Wilson, G Williams
Molecular Brain Research 2000
Ritonavir increases the level of active ADD-1/SREBP-1 protein during adipogenesis:
AT Nguyen, AM Gagnon, JB Angel, A Sorisky
AIDS 2000
A Dominant-negative Peroxisome Proliferator-activated Receptor γ (PPARγ) Mutant Is a Constitutive Repressor and Inhibits PPARγ-mediated Adipogenesis
M Gurnell, JM Wentworth, M Agostini, M Adams, TN Collingwood, C Provenzano, PO Browne, O Rajanayagam, TP Burris, JW Schwabe, MA Lazar, VK Chatterjee
The Journal of biological chemistry 2000
Ligand type-specific Interactions of Peroxisome Proliferator-activated Receptor γ with Transcriptional Coactivators
Y Kodera, K Takeyama, A Murayama, M Suzawa, Y Masuhiro, S Kato
The Journal of biological chemistry 2000
Depot-related and thiazolidinedione-responsive expression of uncoupling protein 2 (UCP2) in human adipocytes
JE Digby, VE Crowley, CP Sewter, JP Whitehead, JB Prins, S O'Rahilly
International Journal of Obesity 2000
New Approaches to Drug Development
P Jollès
2000
Peroxisome Proliferator Activator Receptor-γ Agonists and 15-Deoxy-Δ 12,1412,14 -PGJ 2 Induce Apoptosis in Normal and Malignant B-Lineage Cells
J Padilla, K Kaur, HJ Cao, TJ Smith, RP Phipps
Journal of immunology (Baltimore, Md. : 1950) 2000
A Rational Approach to Drug Therapy of Type 2 Diabetes Mellitus:
JM Chehade, AD Mooradian
Drugs 2000
Therapeutic index for rosiglitazone in dietary obese rats: separation of efficacy and haemodilution
LC Pickavance, M Tadayyon, PS Widdowson, RE Buckingham, JP Wilding
British Journal of Pharmacology 1999
Current Views on the Mechanism of Action of Thiazolidinedione Insulin Sensitizers
BJ Goldstein
Diabetes Technology & Therapeutics 1999
Thiazolidinediones: a new class of antidiabetic drugs
C Day
Diabetic Medicine 1999
Effects of troglitazone on fat distribution in the treatment of male type 2 diabetes
T Kawai, I Takei, Y Oguma, N Ohashi, M Tokui, S Oguchi, F Katsukawa, H Hirose, A Shimada, K Watanabe, T Saruta
Metabolism 1999
Rosiglitazone monotherapy improves glycaemic control in patients with type 2 diabetes: a twelve-week, randomized, placebo-controlled study
J Patel, RJ Anderson, EB Rappaport
Diabetes, Obesity and Metabolism 1999
Troglitazone-Induced Heart and Adipose Tissue Cell Proliferation in Mice
MA Breider, AW Gough, JR Haskins, G Sobocinski, FA la Iglesia
Toxicologic pathology 1999
A Novel Method for Analysis of Nuclear Receptor Function at Natural Promoters: Peroxisome Proliferator-Activated Receptor γ Agonist Actions on aP2 Gene Expression Detected Using Branched DNA Messenger RNA Quantitation
TP Burris, PD Pelton, L Zhou, MC Osborne, E Cryan, KT Demarest
Molecular Endocrinology 1999
Emerging Approaches To The Tissue Engineering Of Fat
AJ Katz, R Llull, MH Hedrick, JW Futrell
Clinics in Plastic Surgery 1999
Type 2 Diabetes: An Overview
HE Lebovitz
Clinical chemistry 1999
Effect of the Pro12Ala variant of the human peroxisome proliferator-activated receptor gamma 2 gene on adiposity, fat distribution, and insulin sensitivity in Japanese men
Y Mori, H Kim-Motoyama, T Katakura, K Yasuda, H Kadowaki, BA Beamer, AR Shuldiner, Y Akanuma, Y Yazaki, T Kadowaki
Biochemical and Biophysical Research Communications 1998
Inhibition of 3T3-L1 Adipocyte Differentiation by Expression of Acyl-CoA-binding Protein Antisense RNA
S Mandrup, RV Sørensen, T Helledie, J Nøhr, T Baldursson, C Gram, J Knudsen, K Kristiansen
The Journal of biological chemistry 1998
Transcription-Modulating Drugs: A New Frontier in the Treatment of Essential Hypertension
TW Kurtz, DG Gardner
Hypertension 1998
Advances in Molecular and Cellular Endocrinology
MR Pollak, EM Brown
Advances in Molecular and Cellular Endocrinology 1997
Obesity and Diabetes
M Smith, R Levine
Medical Clinics of North America 1964

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