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Citations to this article

Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells.
R C Bargou, … , C Scheidereit, B Dörken
R C Bargou, … , C Scheidereit, B Dörken
Published December 15, 1997
Citation Information: J Clin Invest. 1997;100(12):2961-2969. https://doi.org/10.1172/JCI119849.
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Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells.

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Abstract

Research Article

Authors

R C Bargou, F Emmerich, D Krappmann, K Bommert, M Y Mapara, W Arnold, H D Royer, E Grinstein, A Greiner, C Scheidereit, B Dörken

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E McAdam, HN Haboubi, AP Griffiths, JN Baxter, S Spencer-Harty, C Davies, GJ Jenkins
International Journal of Cancer 2014
Epstein-Barr virus and the origin of Hodgkin lymphoma
M Vockerodt, FZ Cader, C Shannon-Lowe, P Murray
Chinese journal of cancer 2014
Divergent Gene Activation in Peripheral Blood and Tissues of Patients with Rheumatoid Arthritis, Psoriatic Arthritis and Psoriasis following Infliximab Therapy
A Rosenberg, H Fan, YG Chiu, R Bolce, D Tabechian, R Barrett, S Moorehead, F Baribaud, H Liu, N Peffer, D Shealy, EM Schwarz, CT Ritchlin, P Proost
PloS one 2014
Nuclear Factor κB–Dependent Regulation of Angiogenesis, and Metastasis in an In Vivo Model of Thyroid Cancer Is Associated With Secreted Interleukin-8
KT Bauerle, RE Schweppe, G Lund, G Kotnis, G Deep, R Agarwal, N Pozdeyev, WM Wood, BR Haugen
The Journal of clinical endocrinology and metabolism 2014
Obesity and cancer: at the crossroads of cellular metabolism and proliferation
RW O’Rourke
Surgery for Obesity and Related Diseases 2014
Constitutive NF-κB activation and tumor-growth promotion by Romo1-mediated reactive oxygen species production
JS Chung, S Lee, YD Yoo
Biochemical and Biophysical Research Communications 2014
Epstein-Barr virus, the germinal centre and the development of Hodgkin's lymphoma
G Mohamed, K Vrzalikova, FZ Cader, M Vockerodt, E Nagy, P Flodr, LF Yap, A Diepstra, PM Kluin, S Rosati, P Murray
Journal of General Virology 2014
The Gβ5 protein regulates sensitivity to TRAIL-induced cell death in colon carcinoma
D Fuchs, M Metzig, M Bickeböller, C Brandel, W Roth
Oncogene 2014
The EF-hand calcium-binding protein tescalcin is a potential oncotarget in colorectal cancer
YH Kang, SR Han, JT Kim, SJ Lee, YI Yeom, JK Min, CH Lee, JW Kim, SR Yoon, DY Yoon, KS Hong, GS Hwang, HC Kim, YH Lee, HG Lee
Oncotarget 2014
Curcumin-based IKKβ inhibiting anticancer lead design using novel fragment-based group QSAR modelling
K Patel, C Tyagi, S Goyal, JK Dhanjal, N Bharadvaja, A Grover
Medicinal Chemistry Research 2014
The novel IκB kinase β inhibitor IMD-0560 prevents bone invasion by oral squamous cell carcinoma
Yukiyo Tada, Shoichiro Kokabu, Goro Sugiyama, Chihiro Nakatomi, Kazuhiro Aoki, Hidefumi Fukushima, Kenji Osawa, Yasutaka Sugamori, Keiichi Ohya, Masato Okamoto, Tomoyuki Fujikawa, Akiko Itai, Kou Matsuo, Seiji Watanabe, Eijiro Jimi
Oncotarget 2014
Paclitaxel in combination with cetuximab exerts antitumor effect by suppressing NF-κB activity in human oral squamous cell carcinoma cell lines
K Harada, T Ferdous, H Kobayashi, Y Ueyama
International journal of oncology 2014
Hodgkin Lymphoma
A Engert, A Younes
2014
The Gβ5 protein regulates sensitivity to TRAIL-induced cell death in colon carcinoma.
Fuchs D, Metzig M, Bickeböller M, Brandel C, Roth W
Oncogene 2014
Antioxidant Function of Isoflavone and 3,3′-Diindolylmethane: Are They Important for Cancer Prevention and Therapy?
Y Li, D Kong, A Ahmad, B Bao, FH Sarkar
Antioxidants & Redox Signaling 2013
Expression and functional relevance of cannabinoid receptor 1 in hodgkin lymphoma
AH Benz, C Renné, E Maronde, M Koch, U Grabiec, S Kallendrusch, B Rengstl, S Newrzela, S Hartmann, ML Hansmann, F Dehghani
PloS one 2013
Doxorubicin induces atypical NF-κB activation through c-Abl kinase activity in breast cancer cells.
Esparza-López J, Medina-Franco H, Escobar-Arriaga E, León-Rodríguez E, Zentella-Dehesa A, Ibarra-Sánchez MJ
Journal of Cancer Research and Clinical Oncology 2013
Inflammation, Oxidative Stress, and Cancer: Dietary Approaches for Cancer Prevention
K Simmons, WL Wang, M Tenniswood, JE Welsh
Inflammation, Oxidative Stress, and Cancer: Dietary Approaches for Cancer Prevention 2013
Doxorubicin induces atypical NF-κB activation through c-Abl kinase activity in breast cancer cells
J Esparza-López, H Medina-Franco, E Escobar-Arriaga, E León-Rodríguez, A Zentella-Dehesa, MJ Ibarra-Sánchez
Journal of Cancer Research and Clinical Oncology 2013
I B-  controls the constitutive NF- B target gene network and survival of ABC DLBCL
H Nogai, SS Wenzel, S Hailfinger, M Grau, E Kaergel, V Seitz, B Wollert-Wulf, M Pfeifer, A Wolf, M Frick, K Dietze, H Madle, A Tzankov, M Hummel, B Dorken, C Scheidereit, M Janz, P Lenz, M Thome, G Lenz
Blood 2013
Unraveling regulatory programs for NF-kappaB, p53 and microRNAs in head and neck squamous cell carcinoma
B Yan, H Li, X Yang, J Shao, M Jang, D Guan, S Zou, CV Waes, Z Chen, M Zhan
PloS one 2013
Nickel ion inhibits nuclear factor-kappa B activity in human oral squamous cell carcinoma
T Shionome, S Endo, D Omagari, M Asano, H Toyoma, T Ishigami, K Komiyama
PloS one 2013
Eukaryotic Initiation Factor 4H Is under Transcriptional Control of p65/NF-κB
G Fiume, A Rossi, A Laurentiis, C Falcone, A Pisano, E Vecchio, M Pontoriero, I Scala, A Scialdone, FF Masci, S Mimmi, C Palmieri, G Scala, I Quinto
PloS one 2013
Biomarkers in advanced larynx cancer
CR Bradford, B Kumar, E Bellile, J Lee, J Taylor, N D'Silva, K Cordell, C Kleer, R Kupfer, P Kumar, S Urba, F Worden, A Eisbruch, GT Wolf, TN Teknos, ME Prince, DB Chepeha, ND Hogikyan, JS Moyer, TE Carey
The Laryngoscope 2013
Aberrant IKKα and IKKβ cooperatively activate NF-κB and induce EGFR/AP1 signaling to promote survival and migration of head and neck cancer
LK Nottingham, CH Yan, X Yang, H Si, J Coupar, Y Bian, TF Cheng, C Allen, P Arun, D Gius, L Dang, CV Waes, Z Chen
Oncogene 2013
Expression and Functional Relevance of Cannabinoid Receptor 1 in Hodgkin Lymphoma
AH Benz, C Renné, E Maronde, M Koch, U Grabiec, S Kallendrusch, B Rengstl, S Newrzela, S Hartmann, ML Hansmann, F Dehghani, P Mukhopadhyay
PloS one 2013
Hodgkin lymphoma: a unique lymphoid malignancy
Ralf Kueppers, Andreas Engert, Martin-Leo Hansmann
Journal of Clinical Investigation 2012
Pathogenetic importance and therapeutic implications of NF-κB in lymphoid malignancies : NF-κB in lymphoid cancer
KH Lim, Y Yang, LM Staudt
Immunological Reviews 2012
Role of Immune Escape Mechanisms in Hodgkin's Lymphoma Development and Progression: A Whole New World with Therapeutic Implications
L la Cruz-Merino, M Lejeune, EN Fernández, FH Carrasco, AG López, AI Vacas, MP Pulla, C Callau, T Alvaro
Clinical and Developmental Immunology 2012
The in vitro study of apoptosis in NB4 cell induced by citral
H Xia, W Liang, Q Song, X Chen, X Chen, J Hong
Cytotechnology 2012
It takes two to tango: IκBs, the multifunctional partners of NF-κB : Biological roles of IκB family proteins
M Hinz, SÇ Arslan, C Scheidereit
Immunological Reviews 2012
Genetic lesions of the TRAF3 and MAP3K14 genes in classical Hodgkin lymphoma
C Otto, M Giefing, A Massow, I Vater, S Gesk, M Schlesner, J Richter, W Klapper, ML Hansmann, R Siebert, R Küppers
British Journal of Haematology 2012
Morphoproteomic confirmation of an activated nuclear factor-кBp65 pathway in follicular thyroid carcinoma
J Liu, RE Brown
International journal of clinical and experimental pathology 2012
Clinical Radiation Oncology
CA Barker, J Yahalom
Clinical Radiation Oncology 2012
Inhibition of nuclear factor-κB by dehydroxymethylepoxyquinomicin induces schedule-dependent chemosensitivity to anticancer drugs and enhances chemoinduced apoptosis in osteosarcoma cells:
AM Castro-Gamero, KS Borges, VS Silveira, RC Lira, RP Queiroz, FC Valera, CA Scrideli, K Umezawa, LG Tone
Anti-Cancer Drugs 2012
Relationship between NF-^|^kappa;B Expression and Malignancy of Canine Mammary Gland Tumor Tissues
L MKAOUAR, Y ENDO, HX JUN, SJ LEE, T JAROENSONG, M MOCHIZUKI, K UCHIDA, H NAKAYAMA, N SASAKI, T NAKAGAWA
Journal of Veterinary Medical Science 2012
The nuclear factor-κB correlates with increased expression of interleukin-6 and promotes progression of gastric carcinoma
Y Yin, X Si, Y Gao, L Gao, J Wang
Oncology reports 2012
Id2 regulates the proliferation of squamous cell carcinoma in vitro via the NF-κB/Cyclin D1 pathway
C Wang, Q Chen, Y Hamajima, W Sun, YQ Zheng, XH Hu, FG Ondrey, JZ Lin
Chinese journal of cancer 2012
To NFκB or not to NFκB: The Dilemma on How to Inhibit a Cancer Cell Fate Regulator
D Sorriento, M Illario, R Finelli, G Iaccarino
Translational medicine @ UniSa 2012
Identification of a Novel Calotropis procera Protein That Can Suppress Tumor Growth in Breast Cancer through the Suppression of NF-κB Pathway
RP Samy, P Rajendran, F Li, NM Anandi, BG Stiles, S Ignacimuthu, G Sethi, VT Chow, MG Castro
PloS one 2012
Analysis of NF- κ B Pathway Proteins in Pediatric Hodgkin Lymphoma: Correlations with EBV Status and Clinical Outcome—A Children's Oncology Group Study
TM Horton, AM Sheehan, RE Hutchison, S Narendra, MF Wu, H Liu
Lymphoma 2012
Hematologic Cancers: From Molecular Pathobiology to Targeted Therapeutics
J Tao, E Sotomayor
2012
Bortezomib-resistant nuclear factor κB expression in stem-like cells in mantle cell lymphoma
HJ Jung, Z Chen, L Fayad, M Wang, J Romaguera, LW Kwak, N McCarty
Experimental Hematology 2011
Inflammation and Gastrointestinal Cancers
JA Jankowski
2011
Inflammation and Gastrointestinal Cancers
JA Jankowski
2011
Inflammation and Gastrointestinal Cancers
JA Jankowski
2011
Inflammation and Gastrointestinal Cancers
JA Jankowski
2011
Targetable molecular pathways in classical Hodgkin's lymphoma
H Adams, EC Obermann, S Dirnhofer, A Tzankov
Expert Opinion on Investigational Drugs 2011
Immune suppression in head and neck cancers: a review
A Duray, S Demoulin, P Hubert, P Delvenne, S Saussez
Clinical & developmental immunology 2011
The Role of Chalcones in Suppression of NF-κB-Mediated Inflammation and Cancer
VR Yadav, S Prasad, B Sung, BB Aggarwal
International Immunopharmacology 2011
Oxidative Stress and Disease
I Paur, M Carlsen, B Halvorsen, R Blomhoff
Herbal Medicine 2011
Deletion of cIAP1 and cIAP2 in murine B lymphocytes constitutively activates cell survival pathways and inactivates the germinal center response
S Gardam, VM Turner, H Anderton, S Limaye, A Basten, F Koentgen, DL Vaux, J Silke, R Brink
Blood 2011
Predictors of histology, tissue eosinophilia and mast cell infiltration in Hodgkin’s Lymphoma - a population-based study
I Glimelius, J Rubin, K Rostgaard, RM Amini, M Simonsson, KM Sorensen, KE Smedby, P Venge, H Hjalgrim, D Molin, G Enblad
European Journal of Haematology 2011
The molecular pathogenesis of Hodgkin lymphoma
K Farrell, RF Jarrett
Histopathology 2011
Bfl-1 is a crucial pro-survival nuclear factor-κB target gene in Hodgkin/Reed-Sternberg cells
ST Loughran, EM Campion, BN D'Souza, SM Smith, K Vrzalikova, K Wen, PG Murray, D Walls
International Journal of Cancer 2011
Bioimaging analysis of nuclear factor-κB activity in Philadelphia chromosome-positive acute lymphoblastic leukemia cells reveals its synergistic upregulation by tumor necrosis factor-α-stimulated changes to the microenvironment
HJ Tsai, S Kobayashi, K Izawa, T Ishida, T Watanabe, K Umezawa, SF Lin, A Tojo
Cancer Science 2011
The aromatic ketone 4′-hydroxychalcone inhibits TNFα-induced NF-κB activation via proteasome inhibition
B Orlikova, D Tasdemir, F Golais, M Dicato, M Diederich
Biochemical Pharmacology 2011
Ets-1 Activates Overexpression of JunB and CD30 in Hodgkin's Lymphoma and Anaplastic Large-Cell Lymphoma
M Watanabe, K Itoh, T Togano, ME Kadin, T Watanabe, M Higashihara, R Horie
The American Journal of Pathology 2011
Notch is an essential upstream regulator of NF-κB and is relevant for survival of Hodgkin and Reed–Sternberg cells
R Schwarzer, B Dörken, F Jundt
Leukemia 2011
Immunohistology of Hodgkin Lymphoma
P Bhargava, ME Kadin
Diagnostic Immunohistochemistry 2011
Beta-catenin signalling: no relevance in Hodgkin lymphoma?
K Sohlbach, R Moll, J Goßmann, O Nowak, P Barth, A Neubauer, MQ Huynh
Leukemia and Lymphoma 2011
Advances in Cancer Research
M Lemaire, S Deleu, ED Bruyne, EV Valckenborgh, E Menu, K Vanderkerken
Advances in Cancer Research Volume 110 2011
Quantifying Nuclear p65 as a Parameter for NF-κB Activation: Correlation Between ImageStream Cytometry, Microscopy and Western Blot
O Maguire, C Collins, K O'Loughlin, J Miecznikowski, H Minderman
Cytometry Part A 2011
Mammalian target of rapamycin and head and neck squamous cell carcinoma
YM Liao, C Kim, Y Yen
Head & neck oncology 2011
Enforced expression of nuclear factor kappa B in p53 deficient keratinocytes induces cell cycle, angiogenic potential and tumorigenesis
EE Caicedo-Granados, BR Wuertz, FG Ondrey
Oral Oncology 2011
Effects of NF-κB Expression and Its Inhibition on Canine Mammary Cancer Cell Lines in an Immunodeficient Mice Model
L MKAOUAR, Y ENDO, M MOCHIZUKI, R NISHIMURA, N SASAKI, T NAKAGAWA
Journal of Veterinary Medical Science 2011
Diagnostic Immunohistochemistry
SP Hammar, S Dacic
Diagnostic Immunohistochemistry 2011
C/EBPα, C/EBPα oncoproteins, or C/EBPβ preferentially bind NF-κB p50 compared with p65, focusing therapeutic targeting on the C/EBP:p50 interaction
JE Dooher, I Paz-Priel, S Houng, AS Baldwin, AD Friedman
Molecular cancer research : MCR 2011
Hodgkin's Lymphomas: A Tumor Recognized by Its Microenvironment
S Montes-Moreno
Advances in Hematology 2011
Hodgkin Disease and the Role of the Immune System
AA Kennedy-Nasser, P Hanley, CM Bollard
Pediatric Hematology-Oncology 2011
Cancer Associated Viruses
ES Robertson
2011
Epigenetic Contributions in Autoimmune Disease
E Ballestar
2011
Bioimaging analysis of nuclear factor‐κB activity in Philadelphia chromosome‐positive acute lymphoblastic leukemia cells reveals its synergistic upregulation by tumor necrosis factor‐α‐stimulated changes to the microenvironment
Tsai H, Kobayashi S, Izawa K, Ishida T, Watanabe T, Umezawa K, Lin S, Tojo A
Cancer Science 2011
3D nuclear organization of telomeres in the Hodgkin cell lines U-HO1 and U-HO1-PTPN1: PTPN1 expression prevents the formation of very short telomeres including "t-stumps"
H Knecht, S Brüderlein, S Wegener, D Lichtensztejn, Z Lichtensztejn, B Lemieux, P Möller, S Mai
BMC cell biology 2010
Growth suppression of mouse pituitary corticotroph tumor AtT20 cells by curcumin: a model for treating Cushing's disease
ML Bangaru, J Woodliff, H Raff, S Kansra
PloS one 2010
Oncogenic activation of NF-kappaB
LM Staudt
Cold Spring Harbor perspectives in biology 2010
NF-κB/STAT3/PI3K signaling crosstalk in iMycEμ B lymphoma
SS Han, H Yun, DJ Son, VS Tompkins, L Peng, ST Chung, JS Kim, ES Park, S Janz
Molecular Cancer 2010
Activating transcription factor-2 in survival mechanisms in head and neck carcinoma cells
D Duffey, S Dolgilevich, S Razzouk, L Li, R Green, GK Gorti
Head & Neck 2010
Mechanisms of aberrant GATA3 expression in classical Hodgkin lymphoma and its consequences for the cytokine profile of Hodgkin and Reed/Sternberg cells
J Stanelle, C Doring, ML Hansmann, R Kuppers
Blood 2010
Kaposi sarcoma-associated herpesvirus-encoded viral FLICE inhibitory protein (vFLIP) K13 cooperates with Myc to promote lymphoma in mice
A Ahmad, JS Groshong, H Matta, S Schamus, V Punj, LJ Robinson, PS Gill, PM Chaudhary
Cancer biology & therapy 2010
Sp1/NFκB/HDAC/miR-29b Regulatory Network in KIT-Driven Myeloid Leukemia
S Liu, LC Wu, J Pang, R Santhanam, S Schwind, YZ Wu, CJ Hickey, J Yu, H Becker, K Maharry, MD Radmacher, C Li, SP Whitman, A Mishra, N Stauffer, AM Eiring, R Briesewitz, RA Baiocchi, KK Chan, P Paschka, MA Caligiuri, JC Byrd, CM Croce, CD Bloomfield, D Perrotti, R Garzon, G Marcucci
Cancer Cell 2010
DJ-1 Enhances Cell Survival through the Binding of Cezanne, a Negative Regulator of NF-κB*
RS McNally, BK Davis, CM Clements, MA Accavitti-Loper, TW Mak, JP Ting
The Journal of biological chemistry 2010
Pediatric Hematology and Oncology
S Weitzman, RM Egeler
Pediatric Hematology and Oncology 2010
Aspirin and other nonsteroidal anti-inflammatory drugs in relation to Hodgkin lymphoma risk in northern Denmark
ET Chang, DP Cronin-Fenton, S Friis, H Hjalgrim, HT Sørensen, L Pedersen
Cancer epidemiology, biomarkers & prevention 2010
Tissue-microarray based immunohistochemical analysis of survival pathways in nodular sclerosing classical Hodgkin lymphoma as compared with Non-Hodgkin's lymphoma
J De, RE Brown
International journal of clinical and experimental medicine 2010
A Phase II trial of the oral mTOR inhibitor everolimus in relapsed Hodgkin lymphoma
PB Johnston, DJ Inwards, JP Colgan, BR Laplant, BF Kabat, TM Habermann, IN Micallef, LF Porrata, SM Ansell, CB Reeder, V Roy, TE Witzig
American Journal of Hematology 2010
Herpesvirus-associated lymphomas: Investigations in humans and animal models
J Rajčáni, N Ásványi-Molnár, S Szathmary
Acta Microbiologica et Immunologica Hungarica 2010
Physiological effects of resveratrol
H Kalantari, DK Das
BioFactors 2010
Signal transduction pathways and transcription factors triggered by arsenic trioxide in leukemia cells
D Sumi, Y Shinkai, Y Kumagai
Toxicology and Applied Pharmacology 2010
Apoptosis of Hodgkin-Reed-Sternberg cells in classical Hodgkin lymphoma revisited
D Benharroch, I Einav, A Feldman, A Levy, S Ariad, J Gopas
APMIS 2010
Combination of ginsenoside Rg3 with docetaxel enhances the susceptibility of prostate cancer cells via inhibition of NF-κB
SM Kim, SY Lee, JS Cho, SM Son, SS Choi, YP Yun, HS Yoo, DY Yoon, KW Oh, SB Han, JT Hong
European Journal of Pharmacology 2010
Dominant expression of survival signals of endoplasmic reticulum stress response in Hodgkin lymphoma
KC Chang, PC Chen, YP Chen, Y Chang, IJ Su
Cancer Science 2010
Captivating Bortezomib: An active but still mysterious drug
FD Raimondo, C Conticello
Leukemia Research 2010
Deficiency of tenascin-C delays articular cartilage repair in mice
N Okamura, M Hasegawa, Y Nakoshi, T Iino, A Sudo, K Imanaka-Yoshida, T Yoshida, A Uchida
Osteoarthritis and Cartilage 2010
Differential chemosensitization of P-glycoprotein overexpressing K562/Adr cells by withaferin A and Siamois polyphenols
W Suttana, S Mankhetkorn, W Poompimon, A Palagani, S Zhokhov, S Gerlo, G Haegeman, WV Berghe
Molecular Cancer 2010
Inhibiting NF-κB Activation by Small Molecules As a Therapeutic Strategy
SC Gupta, C Sundaram, S Reuter, BB Aggarwal
Biochimica et Biophysica Acta 2010
Correlation of NF-κB signal pathway with tumor metastasis of human head and neck squamous cell carcinoma
M Yan, Q Xu, P Zhang, X Zhou, Z Zhang, W Chen
BMC Cancer 2010
Novel treatment strategies for patients with relapsed classical Hodgkin lymphoma
A Jona, A Younes
Blood Reviews 2010
PYRIN domain of NALP2 inhibits cell proliferation and tumor growth of human glioblastoma
GQ Wu, YJ Liao, ZQ Qin, LR He, YC Chen, YX Zeng, HF Kung, D Xie
Plasmid 2010
Brucea javanica Oil Induces Apoptosis in T24 Bladder Cancer Cells via Upregulation of Caspase-3, Caspase-9, and Inhibition of NF-κB and COX-2 Expressions
GG Lou, HP Yao, LP Xie
The American journal of Chinese medicine 2010
Mutations of NFKBIA in biopsy specimens from Hodgkin lymphoma
X Liu, H Yu, W Yang, X Zhou, H Lu, D Shi
Cancer Genetics and Cytogenetics 2010
3D structural and functional characterization of the transition from Hodgkin to Reed-Sternberg cells
H Knecht, S Brüderlein, S Mai, P Möller, B Sawan
Annals of Anatomy - Anatomischer Anzeiger 2010
NF-κB as a potential therapeutic target in myelodysplastic syndromes and acute myeloid leukemia
M Breccia, G Alimena
Expert Opinion on Therapeutic Targets 2010
DJ-1 Enhances Cell Survival through the Binding of Cezanne, a Negative Regulator of NF-κB
RS McNally, BK Davis, CM Clements, MA Accavitti-Loper, TW Mak, JP Ting
The Journal of biological chemistry 2010
Molecular Pathology of Hematolymphoid Diseases
CH Dunphy
2010
Nasopharyngeal Cancer
JJ Lu, JS Cooper, AW Lee
2010
A new synthetic protein, TAT-RH, inhibits tumor growth through the regulation of NFκB activity
D Sorriento, A Campanile, G Santulli, E Leggiero, L Pastore, B Trimarco, G Iaccarino
Molecular Cancer 2009
Regulation and Function of NF-κB Transcription Factors in the Immune System
S Vallabhapurapu, M Karin
Annual Review of Immunology 2009
Epstein-Barr Virus in Lymphoproliferative Processes
SB Ng, JD Khoury
Advances in Anatomic Pathology 2009
The integrin alpha2beta1 agonist, aggretin, promotes proliferation and migration of VSMC through NF-kB translocation and PDGF production
CH Chung, KT Lin, CH Chang, HC Peng, TF Huang
British Journal of Pharmacology 2009
Characterization of anti-NF-kappaB RNA aptamer-binding specificity in vitro and in the yeast three-hybrid system
SE Wurster, JP Bida, YF Her, LJ 3rd
Nucleic Acids Research 2009
EBV in Hodgkin Lymphoma
G Massini, D Siemer, S Hohaus
Mediterranean journal of hematology and infectious diseases 2009
NF-kappaB and cancer: how intimate is this relationship
S Prasad, J Ravindran, BB Aggarwal
Molecular and Cellular Biochemistry 2009
Neurotrophin signaling through tropomyosin receptor kinases contributes to survival and proliferation of non-Hodgkin lymphoma
LF Sniderhan, TM Garcia-Bates, M Burgart, SH Bernstein, RP Phipps, SB Maggirwar
Experimental Hematology 2009
Mutations in the genes coding for the NF-κB regulating factors IκBα and A20 are uncommon in nodular lymphocyte-predominant Hodgkin's lymphoma
MA Schumacher, R Schmitz, V Brune, E Tiacci, C Döring, ML Hansmann, R Siebert, R Küppers
Haematologica 2009
TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma
R Schmitz, ML Hansmann, V Bohle, JI Martin-Subero, S Hartmann, G Mechtersheimer, W Klapper, I Vater, M Giefing, S Gesk, J Stanelle, R Siebert, R Küppers
Journal of Experimental Medicine 2009
Comparative analysis of oncogenic properties and nuclear factor-kappaB activity of latent membrane protein 1 natural variants from Hodgkin's lymphoma's Reed-Sternberg cells and normal B-lymphocytes
N Faumont, A Chanut, A Benard, N Cogne, G Delsol, J Feuillard, F Meggetto
Haematologica 2009
Combination bortezomib and rituximab treatment affects multiple survival and death pathways to promote apoptosis in mantle cell lymphoma
L Alinari, VL White, CT Earl, TP Ryan, JS Johnston, JT Dalton, AK Ferketich, R Lai, DM Lucas, P Porcu, KA Blum, JC Byrd, RA Baiocchi
mAbs 2009
Loss of endogenous interleukin-12 activates survival signals in ultraviolet-exposed mouse skin and skin tumors
SM Meeran, N Katiyar, T Singh, SK Katiyar
Neoplasia (New York, N.Y.) 2009
Proteasome Inhibitor MG132 Inhibits Angiogenesis in Pancreatic Cancer by Blocking NF-κB Activity
Y Matsuo, H Sawai, N Ochi, A Yasuda, M Sakamoto, H Takahashi, H Funahashi, H Takeyama, S Guha
Digestive Diseases and Sciences 2009
STAT6 and STAT1 are essential antagonistic regulators of cell survival in classical Hodgkin lymphoma cell line
D Baus, F Nonnenmacher, S Jankowski, C Döring, C Bräutigam, M Frank, ML Hansmann, E Pfitzner
Leukemia 2009
Mutations ofNFKBIA, encoding IκBα, are a recurrent finding in classical Hodgkin lymphoma but are not a unifying feature of non-EBV-associated cases
A Lake, LA Shield, P Cordano, DT Chui, J Osborne, S Crae, KS Wilson, S Tosi, SJ Knight, S Gesk, R Siebert, RT Hay, RF Jarrett
International Journal of Cancer 2009
Heat stress triggers apoptosis by impairing NF-κB survival signaling in malignant B cells
G Belardo, R Piva, MG Santoro
Leukemia 2009
Novel treatment strategies for patients with relapsed classical Hodgkin lymphoma
A Younes
Hematology 2009
Molecular biology of Hodgkin lymphoma
R Kuppers
Hematology 2009
TRAF1 is involved in the classical NF-κB activation and CD30-induced alternative activity in Hodgkin's lymphoma cells
F Guo, A Sun, W Wang, J He, J Hou, P Zhou, Z Chen
Molecular Immunology 2009
Pathogenesis of Classical and Lymphocyte-Predominant Hodgkin Lymphoma
R Schmitz, J Stanelle, ML Hansmann, R Küppers
Annual Review of Pathology: Mechanisms of Disease 2009
Polymorphisms and haplotypes in TLR9 and MYD88 are associated with the development of Hodgkin's lymphoma: a candidate–gene association study
V Mollaki, T Georgiadis, A Tassidou, M Ioannou, Z Daniil, A Koutsokera, AA Papathanassiou, E Zintzaras, G Vassilopoulos
Journal of Human Genetics 2009
Functional aspects of the CD30 gene in Hodgkin’s lymphoma and anaplastic large cell lymphoma
DS Ho, AJ Rea, LJ Abraham
Oncology Reviews 2009
Epigenetic dysregulation of the host cell genome in Epstein–Barr virus-associated neoplasia
HH Niller, H Wolf, J Minarovits
Seminars in Cancer Biology 2009
Targeting the Bcl-2 family of proteins in Hodgkin lymphoma:in vitrocytotoxicity, target modulation and drug combination studies of the Bcl-2 homology 3 mimetic ABT-737
A Jayanthan, SC Howard, T Trippett, T Horton, JA Whitlock, L Daisley, V Lewis, A Narendran
Leukemia & Lymphoma 2009
Fighting Cancer with Red Wine? Molecular Mechanisms of Resveratrol
TE Kraft, D Parisotto, C Schempp, T Efferth
Critical Reviews in Food Science and Nutrition 2009
Oncology of Infancy and Childhood
MJ O'Sullivan, JA Fletcher, CA Felix
Oncology of Infancy and Childhood 2009
Evodiamine-induced human melanoma A375-S2 cell death was mediated by PI3K/Akt/caspase and Fas-L/NF-kappaB signaling pathways and augmented by ubiquitin-proteasome inhibition
C Wang, S Li, M Wang
Toxicology in vitro : an international journal published in association with BIBRA 2009
K-Ras Promotes Angiogenesis Mediated by Immortalized Human Pancreatic Epithelial Cells through Mitogen-Activated Protein Kinase Signaling Pathways
Y Matsuo, PM Campbell, RA Brekken, B Sung, MM Ouellette, JB Fleming, BB Aggarwal, CJ Der, S Guha
Molecular cancer research : MCR 2009
Lymphoma in Adolescents and Young Adults
SM Jaglowski, E Linden, AM Termuhlen, JM Flynn
Seminars in Oncology 2009
Exhaled Nitric Oxide and Nitric Oxide Synthase Expression in Hodgkin's Disease
G Guida, B Culla, T Scirelli, G Bellone, S Sciascia, L Brussino, D Novero, G Palestro, E Heffler, P Gavarotti, G Rolla, C Bucca
International journal of immunopathology and pharmacology 2009
Obovatol Enhances Docetaxel-Induced Prostate and Colon Cancer Cell Death Through Inactivation of Nuclear Transcription Factor-κB
SY Lee, JS Cho, DY Yuk, DC Moon, JK Jung, HS Yoo, YM Lee, SB Han, KW Oh, JT Hong
Journal of Pharmacological Sciences 2009
Drug Resistance in Cancer Cells
ZH Siddik, K Mehta
2009
Polymorphic Variation in NFKB1 and Other Aspirin-Related Genes and Risk of Hodgkin Lymphoma
ET Chang, BM Birmann, JL Kasperzyk, DV Conti, P Kraft, RF Ambinder, T Zheng, NE Mueller
Cancer epidemiology, biomarkers & prevention 2009
Overexpressed NF-kappaB-inducing kinase contributes to the tumorigenesis of adult T-cell leukemia and Hodgkin Reed-Sternberg cells
Y Saitoh, N Yamamoto, MZ Dewan, H Sugimoto, VJ Bruyn, Y Iwasaki, K Matsubara, X Qi, T Saitoh, I Imoto, J Inazawa, A Utsunomiya, T Watanabe, T Masuda, N Yamamoto, S Yamaoka
Blood 2008
Origin and pathogenesis of nodular lymphocyte-predominant Hodgkin lymphoma as revealed by global gene expression analysis
V Brune, E Tiacci, I Pfeil, C Döring, S Eckerle, CJ van Noesel, W Klapper, B Falini, A Heydebreck, D Metzler, A Bräuninger, ML Hansmann, R Küppers
Journal of Experimental Medicine 2008
CD30-induced signaling is absent in Hodgkin's cells but present in anaplastic large cell lymphoma cells
B Hirsch, M Hummel, S Bentink, F Fouladi, R Spang, R Zollinger, H Stein, H Dürkop
The American Journal of Pathology 2008
Nasopharyngeal carcinoma--review of the molecular mechanisms of tumorigenesis
J Chou, YC Lin, J Kim, L You, Z Xu, B He, DM Jablons
Head & Neck 2008
Programmed Cell Death in Cancer Progression and Therapy
R Khosravi-Far, E White
2008
Programmed Cell Death in Cancer Progression and Therapy
R Khosravi-Far, E White
2008
Programmed Cell Death in Cancer Progression and Therapy
R Khosravi-Far, E White
2008
Programmed Cell Death in Cancer Progression and Therapy
R Khosravi-Far, E White
2008
Programmed Cell Death in Cancer Progression and Therapy
R Khosravi-Far, E White
2008
Programmed Cell Death in Cancer Progression and Therapy
R Khosravi-Far, E White
2008
Regulation and dysregulation of Epstein–Barr virus latency: Implications for the development of autoimmune diseases
HH Niller, H Wolf, J Minarovits
Autoimmunity 2008
IL-21 is expressed in Hodgkin lymphoma and activates STAT5: evidence that activated STAT5 is required for Hodgkin lymphomagenesis
FA Scheeren, SA Diehl, LA Smit, T Beaumont, M Naspetti, RJ Bende, B Blom, K Karube, K Ohshima, CJ van Noesel, H Spits
Blood 2008
Prednisolone inhibits PDGF-induced nuclear translocation of NF-kappaB in human pulmonary artery smooth muscle cells
A Ogawa, AL Firth, W Yao, LJ Rubin, JX Yuan
American journal of physiology. Lung cellular and molecular physiology 2008
Retracted: A modified version of galectin-9 induces cell cycle arrest and apoptosis of Burkitt and Hodgkin lymphoma cells
S Makishi, T Okudaira, C Ishikawa, S Sawada, T Watanabe, M Hirashima, H Sunakawa, N Mori
British Journal of Haematology 2008
Nuclear factor-κB activation and differential expression of survivin and Bcl-2 in human grade 2-4 astrocytomas
FF Angileri, MH Aguennouz, A Conti, DL Torre, S Cardali, R Crupi, C Tomasello, A Germanò, G Vita, F Tomasello
Cancer 2008
Repression of B-cell linker (BLNK) and B-cell adaptor for phosphoinositide 3-kinase (BCAP) is important for lymphocyte transformation by rel proteins
N Gupta, J Delrow, A Drawid, AM Sengupta, G Fan, C Gélinas
Cancer research 2008
Prevalence of bortezomib-resistant constitutive NF-kappaB activity in mantle cell lymphoma
DT Yang, KH Young, BS Kahl, S Markovina, S Miyamoto
Molecular Cancer 2008
The IKK-neutralizing compound Bay11 kills supereffector CD8 T cells by altering caspase-dependent activation-induced cell death
SJ Lee, M Long, AJ Adler, RS Mittler, AT Vella
Journal of leukocyte biology 2008
A distinctive physiological role for IkappaBbeta in the propagation of mitochondrial respiratory stress signaling
G Biswas, W Tang, N Sondheimer, M Guha, S Bansal, NG Avadhani
The Journal of biological chemistry 2008
Apoptosis and tumor resistance conferred by Par-4
Y Zhao, VM Rangnekar
Cancer biology & therapy 2008
IKK-2 is required for TNF-α-induced invasion and proliferation of human mesenchymal stem cells
W Böcker, D Docheva, WC Prall, V Egea, E Pappou, O Roßmann, C Popov, W Mutschler, C Ries, M Schieker
Journal of Molecular Medicine 2008
Plumbagin-induced Apoptosis in Human Prostate Cancer Cells is Associated with Modulation of Cellular Redox Status and Generation of Reactive Oxygen Species
AA Powolny, SV Singh
Pharmaceutical Research 2008
Curcumin induces cell-arrest and apoptosis in association with the inhibition of constitutively active NF-κB and STAT3 pathways in Hodgkin's lymphoma cells
GG Mackenzie, N Queisser, ML Wolfson, CG Fraga, AM Adamo, PI Oteiza
International Journal of Cancer 2008
Role of immunoexpression of nitric oxide synthases by Hodgkin and Reed-Sternberg cells on apoptosis deregulation and on clinical outcome of classical Hodgkin lymphoma
AH Campos, VL Aldred, KC Ribeiro, J Vassallo, FA Soares
Molecular and Cellular Biochemistry 2008
The role of NF-κB in lymphoid malignancies
G Packham
British Journal of Haematology 2008
Targetable oncogenic pathways in Hodgkin and Reed-Sternberg cells of classical Hodgkin lymphoma
A Tzankov
memo - Magazine of European Medical Oncology 2008
Inhibitory activity of nuclear factor-κB potentiates cisplatin-induced apoptosis in A549 cells
J Zhang, Y Xu, W Xiong, Z Zhang, C Du, L Qiao, W Ni, S Chen
Journal of Huazhong University of Science and Technology [Medical Sciences] 2008
Bortezomib induces caspase-dependent apoptosis in Hodgkin lymphoma cell lines and is associated with reduced c-FLIP expression: A gene expression profiling study with implications for potential combination therapies
X Zhao, W Qiu, J Kung, X Zhao, X Peng, M Yegappan, B Yen-Lieberman, ED Hsi
Leukemia Research 2008
NF-κB Signaling Pathway and Its Therapeutic Implications in Human Diseases
FH Sarkar, Y Li, Z Wang, D Kong
International Reviews of Immunology 2008
Biologic features of Hodgkin lymphoma and the development of biologic prognostic factors in Hodgkin lymphoma: Tumor and microenvironment
ED Hsi
Leukemia & Lymphoma 2008
Stimulation of interleukin-13 expression by human T-cell leukemia virus type 1 oncoprotein Tax via a dually active promoter element responsive to NF- B and NFAT
K Silbermann, G Schneider, R Grassmann
Journal of General Virology 2008
Expression of CCL17 and CCL22 by latent membrane protein 1-positive tumor cells in age-related Epstein–Barr virus-associated B-cell lymphoproliferative disorder
S Takegawa, Z Jin, T Nakayama, T Oyama, K Hieshima, D Nagakubo, AK Shirakawa, T Tsuzuki, S Nakamura, O Yoshie
Cancer Science 2008
Expression of the translation initiation factors eIF-4E and eIF-2α is frequently increased in neoplastic cells of Hodgkin lymphoma
IB Rosenwald, L Koifman, L Savas, JJ Chen, BA Woda, ME Kadin
Human Pathology 2008
Systems biology-defined NF-κB regulons, interacting signal pathways and networks are implicated in the malignant phenotype of head and neck cancer cell lines differing in p53 status
B Yan, G Chen, K Saigal, X Yang, ST Jensen, CV Waes, CJ Stoeckert, Z Chen
Genome biology 2008
The Role of the NF-kappaB Transcriptome and Proteome as Biomarkers in Human Head and Neck Squamous Cell Carcinomas*
Z Chen, B Yan, CV Waes
Biomarkers in Medicine 2008
Molecular Biology of Head & Neck Cancer: Risks and Pathways
ME Stadler, MR Patel, ME Couch, DN Hayes
Hematology/Oncology Clinics of North America 2008
Dynamic Effect of Bortezomib on NF-κB Activity and Gene Expression in Tumor Cells
MH Sung, L Bagain, Z Chen, T Karpova, X Yang, C Silvin, TC Voss, JG McNally, CV Waes, GL Hager
Molecular pharmacology 2008
Hematopathology
F Naeim
Hematopathology 2008
Anti-NF-kappaB and anti-inflammatory activities of synthetic isothiocyanates: effect of chemical structures and cellular signaling
A Prawan, CL Saw, TO Khor, YS Keum, S Yu, L Hu, AN Kong
Chemico-Biological Interactions 2008
A Distinctive Physiological Role for IκBβ in the Propagation of Mitochondrial Respiratory Stress Signaling
G Biswas, W Tang, N Sondheimer, M Guha, S Bansal, NG Avadhani
The Journal of biological chemistry 2008
Prednisolone inhibits PDGF-induced nuclear translocation of NF-κB in human pulmonary artery smooth muscle cells
A Ogawa, AL Firth, W Yao, LJ Rubin, JX Yuan
American journal of physiology. Lung cellular and molecular physiology 2008
Nuclear Factor-κB Activation: From Bench to Bedside
G Sethi, B Sung, BB Aggarwal
Experimental biology and medicine (Maywood, N.J.) 2008
Innate and Adaptive Immunity in the Tumor Microenvironment
E Yefenof
2008
CAPERα Is a Novel Rel-TAD-Interacting Factor That Inhibits Lymphocyte Transformation by the Potent Rel/NF-κB Oncoprotein v-Rel
J Dutta, G Fan, C Gélinas
Journal of virology 2008
Inhibitory activity of nuclear factor-kappaB potentiates cisplatin-induced apoptosis in A549 cells.
Zhang J, Xu Y, Xiong W, Zhang Z, Du C, Qiao L, Ni W, Chen S
2008
Role of immunoexpression of nitric oxide synthases by Hodgkin and Reed-Sternberg cells on apoptosis deregulation and on clinical outcome of classical Hodgkin lymphoma.
Campos AH, Aldred VL, Ribeiro KC, Vassallo J, Soares FA
Molecular and Cellular Biochemistry 2008
Plumbagin-induced apoptosis in human prostate cancer cells is associated with modulation of cellular redox status and generation of reactive oxygen species.
Powolny AA, Singh SV
Pharmaceutical Research 2008
Expression of CCL17 and CCL22 by latent membrane protein 1‐positive tumor cells in age‐related Epstein–Barr virus‐associated B‐cell lymphoproliferative disorder
Takegawa S, Jin Z, Nakayama T, Oyama T, Hieshima K, Nagakubo D, Shirakawa A, Tsuzuki T, Nakamura S, Yoshie O
Cancer Science 2008
Astrocyte elevated gene-1: recent insights into a novel gene involved in tumor progression, metastasis and neurodegeneration
L Emdad, D Sarkar, ZZ Su, SG Lee, DC Kang, JN Bruce, DJ Volsky, PB Fisher
Pharmacology & Therapeutics 2007
The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease
BB Aggarwal, YJ Surh, S Shishodia
2007
The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease
BB Aggarwal, YJ Surh, S Shishodia
2007
The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease
BB Aggarwal, YJ Surh, S Shishodia
2007
Apoptosis and antiapoptotic mechanisms in the progression of myelodysplastic syndrome
DB Kerbauy, HJ Deeg
Experimental Hematology 2007
Targeted Therapies in Cancer
M Dietel
2007
EBV Latent Membrane Protein 1 Activates Akt, NFκB, and Stat3 in B Cell Lymphomas
KH Shair, KM Bendt, RH Edwards, EC Bedford, JN Nielsen, N Raab-Traub, S Virgin
PLoS pathogens 2007
Nuclear factor-κB-dependent cyclin D1 induction and DNA replication associated with N-methyl-D-aspartate receptor-mediated apoptosis in rat striatum
ZQ Liang, X Wang, LY Li, Y Wang, RW Chen, DM Chuang, TN Chase, ZH Qin
Journal of Neuroscience Research 2007
Contribution of the Epstein Barr virus to the molecular pathogenesis of Hodgkin lymphoma
G Kapatai, P Murray
Journal of clinical pathology 2007
Loss of bHLH transcription factor E2A activity in primary effusion lymphoma confers resistance to apoptosis
A Lietz, M Janz, M Sigvardsson, F Jundt, B Dörken, S Mathas
British Journal of Haematology 2007
Pharmacologic activation of p53-dependent and p53-independent apoptotic pathways in Hodgkin/Reed-Sternberg cells
M Janz, T Stühmer, LT Vassilev, RC Bargou
Leukemia 2007
Nitric oxide induces apoptosis in cutaneous T cell lymphoma (HuT-78) by downregulating constitutive NF-κB
L Rishi, R Dhiman, M Raje, S Majumdar
Biochimica et Biophysica Acta (BBA) - General Subjects 2007
High expression of several tyrosine kinases and activation of the PI3K/AKT pathway in mediastinal large B cell lymphoma reveals further similarities to Hodgkin lymphoma
C Renné, K Willenbrock, JI Martin-Subero, N Hinsch, C Döring, E Tiacci, W Klapper, P Möller, R Küppers, ML Hansmann, R Siebert, A Bräuninger
Leukemia 2007
Tissue transglutaminase-mediated chemoresistance in cancer cells
A Verma, K Mehta
Drug Resistance Updates 2007
Gains ofREL in primary mediastinal B-cell lymphoma coincide with nuclear accumulation of REL protein
MA Weniger, S Gesk, S Ehrlich, JI Martin-Subero, MJ Dyer, R Siebert, P Möller, TF Barth
Genes, Chromosomes and Cancer 2007
Epstein–Barr virus infection in humans: from harmless to life endangering virus–lymphocyte interactions
E Klein, LL Kis, G Klein
Oncogene 2007
NF-?B and apoptosis in colorectal tumourigenesis
MM Aranha, PM Borralho, P Ravasco, IB da Silva, L Correia, A Fernandes, ME Camilo, CM Rodrigues
European Journal of Clinical Investigation 2007
IκBα independent induction of NF-κB and its inhibition by DHMEQ in Hodgkin/Reed-Sternberg cells
M Watanabe, MZ Dewan, M Taira, M Shoda, M Honda, T Sata, M Higashihara, ME Kadin, T Watanabe, N Yamamoto, K Umezawa, R Horie
Laboratory Investigation 2007
Absence of measles virus genome and transcripts in Hodgkin-Reed/Sternberg cells of a cohort of Hodgkin lymphoma patients
E Maggio, D Benharroch, J Gopas, U Dittmer, ML Hansmann, R Küppers
International Journal of Cancer 2007
Arsenic: Signal Transduction, Transcription Factor, and Biotransformation Involved in Cellular Response and Toxicity
Y Kumagai, D Sumi
Annual Review of Pharmacology and Toxicology 2007
Transcription Factors as Therapeutic Targets in Lymphoid Malignancies
T Sanda
International Reviews of Immunology 2007
Hodgkin-lymphoma-derived cells show high sensitivity to dactinomycin and paclitaxel
L Markasz, LL Kis, G Stuber, E Flaberg, R Otvos, S Eksborg, H Skribek, E Olah, L Szekely
Leukemia & Lymphoma 2007
Recent insights into the biology of Hodgkin lymphoma: unraveling the mysteries of the Reed–Sternberg cell
MR Roullet, A Bagg
Expert Review of Molecular Diagnostics 2007
NF-κB controls growth of glioblastomas/astrocytomas
D Smith, T Shimamura, S Barbera, BE Bejcek
Molecular and Cellular Biochemistry 2007
TheCD30 gene promoter microsatellite binds transcription factor Yin Yang 1 (YY1) and shows genetic instability in anaplastic large cell lymphoma
M Franchina, AJ Woo, J Dods, M Karimi, D Ho, T Watanabe, DV Spagnolo, LJ Abraham
The Journal of Pathology 2007
Relapsed and Refractory Hodgkin Lymphoma: Transplantation Strategies and Novel Therapeutic Options
KA David, L Mauro, AM Evens
Current Treatment Options in Oncology 2007
Expression of bcl2 family proteins and active caspase 3 in classical Hodgkin's lymphomas
M Bai, A Papoudou-Bai, N Horianopoulos, C Grepi, NJ Agnantis, P Kanavaros
Human Pathology 2007
The Pathogenesis of Classical Hodgkin's Lymphoma: A Model for B-Cell Plasticity
S Mathas
Hematology/Oncology Clinics of North America 2007
Genome-wide identification of novel expression signatures reveal distinct patterns and prevalence of binding motifs for p53, nuclear factor-κB and other signal transcription factors in head and neck squamous cell carcinoma
B Yan, X Yang, TL Lee, J Friedman, J Tang, CV Waes, Z Chen
Genome biology 2007
Perspectives in Medical Virology
KD Mena
Perspectives in Medical Virology 2007
Targeting Antiapoptotic Bcl-2 Family Members with Cell-Permeable BH3 Peptides Induces Apoptosis Signaling and Death in Head and Neck Squamous Cell Carcinoma Cells12
R Li, AL Boehm, MB Miranda, S Shangary, JR Grandis, DE Johnson
Neoplasia (New York, N.Y.) 2007
Proteasome inhibition-induces endoplasmic reticulum dysfunction and cell death of human cholangiocarcinoma cells
Y Ustundag, SF Bronk, GJ Gores
World journal of gastroenterology : WJG 2007
Nuclear factor-kB in thyroid carcinogenesis and progression: a novel therapeutic target for advanced thyroid cancer
H Namba, V Saenko, S Yamashita
Arquivos brasileiros de endocrinologia e metabologia 2007
Aids-Associated Viral Oncogenesis
C Meyers
2007
Pediatric Lymphomas
HJ Weinstein, MM Hudson, MP Link
2007
Cytokines in the Genesis and Treatment of Cancer
MA Caligiuri, MT Lotze
2007
NF-kappaB controls growth of glioblastomas/astrocytomas.
Smith D, Shimamura T, Barbera S, Bejcek BE
Molecular and Cellular Biochemistry 2007
Relapsed and refractory Hodgkin lymphoma: transplantation strategies and novel therapeutic options.
David KA, Mauro L, Evens AM
Current Treatment Options in Oncology 2007
Hodgkin lymphoma cells express TACI and BCMA receptors and generate survival and proliferation signals in response to BAFF and APRIL
A Chiu, W Xu, B He, SR Dillon, JA Gross, E Sievers, X Qiao, P Santini, E Hyjek, J Lee, E Cesarman, A Chadburn, DM Knowles, A Cerutti
Blood 2006
Epstein–Barr virus-associated lymphomas
MK Gandhi
Expert Review of Anti-infective Therapy 2006
Tobacco smoking, alcohol drinking and Hodgkin's lymphoma: a European multi-centre case-control study (EPILYMPH)
H Besson, P Brennan, N Becker, SD Sanjosé, A Nieters, R Font, M Maynadié, L Foretova, PL Cocco, A Staines, M Vornanen, P Boffetta
British Journal of Cancer 2006
Molecular cross-talk between the NFkappaB and STAT3 signaling pathways in head and neck squamous cell carcinoma
CH Squarize, RM Castilho, V Sriuranpong, DS Pinto, JS Gutkind
Neoplasia (New York, N.Y.) 2006
NF-κB: A Stress-Regulated Switch for Cell Survival
R Piva, G Belardo, MG Santoro
Antioxidants & Redox Signaling 2006
The role of Epstein–Barr virus in cancer
SB Pattle, PJ Farrell
Expert Opinion on Biological Therapy 2006
Cytokine mediated induction of the major Epstein–Barr virus (EBV)-encoded transforming protein, LMP-1
LL Kis, M Takahara, N Nagy, G Klein, E Klein
Immunology Letters 2006
Hodgkin’s lymphoma: molecular targets and novel treatment strategies
V Yazbeck, GV Georgakis, A Wedgwood, A Younes
Future Oncology 2006
Minimal change nephrotic syndrome and classical Hodgkin's lymphoma: Report of 21 cases and review of the literature
V Audard, F Larousserie, P Grimbert, M Abtahi, JJ Sotto, A Delmer, F Boue, D Nochy, N Brousse, R Delarue, P Remy, P Ronco, D Sahali, P Lang, O Hermine
Kidney International 2006
The effect of Epstein–Barr virus status on clinical outcome in Hodgkin’s lymphoma
JM Kwon, YH Park, JH Kang, K Kim, YH Ko, BY Ryoo, SS Lee, SI Lee, HH Koo, WS Kim
Annals of Hematology 2006
Targeting NF-κB in hematologic malignancies
T Braun, G Carvalho, C Fabre, J Grosjean, P Fenaux, G Kroemer
Cell Death and Differentiation 2006
NF-κB and IKK as therapeutic targets in cancer
HJ Kim, N Hawke, AS Baldwin
Cell Death and Differentiation 2006
Molecular biology of Hodgkin's and Reed/Sternberg cells in Hodgkin's lymphoma
A Bräuninger, R Schmitz, D Bechtel, C Renné, ML Hansmann, R Küppers
International Journal of Cancer 2006
The involvement of nuclear factor-kappa B in cyclooxygenase-2 overexpression in murine colon cancer cells transduced with herpes simplex virus thymidine kinase gene
A Konson, JA Mahajna, A Danon, G Rimon, R Agbaria
Cancer Gene Therapy 2006
Current insights into the regulation of programmed cell death by NF-κB
J Dutta, Y Fan, N Gupta, G Fan, C Gélinas
Oncogene 2006
Mutations in the NF-κB signaling pathway: implications for human disease
G Courtois, TD Gilmore
Oncogene 2006
Nuclear factor-κB and inhibitor of κB kinase pathways in oncogenic initiation and progression
DS Bassères, AS Baldwin
Oncogene 2006
Thalidomide and celecoxib as potential modulators of irinotecan’s activity in cancer patients
M Villalona-Calero, L Schaaf, G Phillips, G Otterson, K Panico, W Duan, B Kleiber, M Shah, D Young, WH Wu, J Kuhn
Cancer Chemotherapy and Pharmacology 2006
Gene expression profiling of breast cancer cells in response to gemcitabine: NF-κB pathway activation as a potential mechanism of resistance
H Hernández-Vargas, SM Rodríguez-Pinilla, M Julián-Tendero, P Sánchez-Rovira, C Cuevas, A Antón, MJ Ríos, J Palacios, G Moreno-Bueno
Breast Cancer Research and Treatment 2006
Specific function of STAT3, SOCS1, and SOCS3 in the regulation of proliferation and survival of classical Hodgkin lymphoma cells
D Baus, E Pfitzner
International Journal of Cancer 2006
Dysfunctional p53 deletion mutants in cell lines derived from Hodgkin's lymphoma
A Feuerborn, C Möritz, FV Bonin, M Dobbelstein, L Trümper, B Stürzenhofecker, D Kube
Leukemia & Lymphoma 2006
Epstein-Barr virus, cytokines, and inflammation: A cocktail for the pathogenesis of Hodgkin's lymphoma?
G Khan
Experimental Hematology 2006
Signalling and survival pathways in multiple myeloma
K Bommert, RC Bargou, T Stühmer
European Journal of Cancer 2006
Activation of multiple molecular mechanisms for apoptosis in human malignant glioblastoma T98G and U87MG cells treated with sulforaphane
S Karmakar, MS Weinberg, NL Banik, SJ Patel, SK Ray
Neuroscience 2006
Handbook of Transcription Factor NF-kappaB
A Baldwin
Handbook of Transcription Factor NF-kappaB 2006
NF-κB in solid tumors
F Pacifico, A Leonardi
Biochemical Pharmacology 2006
Proteasome inhibitors and modulators of heat shock protein function
DJ Kuhn, EL Zeger, RZ Orlowski
Update on cancer therapeutics 2006
Molecular Cross-Talk between the NFκB and STAT3 Signaling Pathways in Head and Neck Squamous Cell Carcinoma
CH Squarize, RM Castilho, V Sriuranpong, DS Pinto, JS Gutkind
Neoplasia (New York, N.Y.) 2006
Deregulated NF-κB activity in haematological malignancies
A Keutgens, I Robert, P Viatour, A Chariot
Biochemical Pharmacology 2006
Advances in Biology, Diagnostics, and Treatment of Hodgkin’s Disease
R Küppers, J Yahalom, A Josting
Biology of Blood and Marrow Transplantation 2006
Modulation of transcription factor NF-κB in Hodgkin's lymphoma cell lines: Effect of (−)-epicatechin
GG Mackenzie, PI Oteiza
Free Radical Research 2006
The Link Between Inflammation and Cancer
AG Dalgleish, B Haefner
2006
Pathobiology of Classical Hodgkin Lymphoma
A Tzankov, S Dirnhofer
Pathobiology 2006
NF-κB/Rel Transcription Factor Family
HC Liou
2006
Classical Hodgkin lymphoma: an epigenetically determined disease?
JF García
Blood 2006
Aberrant NF-κB signaling in lymphoma: mechanisms, consequences, and therapeutic implications
PJ Jost, J Ruland
Blood 2006
Bmi-1 is induced by the Epstein-Barr virus oncogene LMP1 and regulates the expression of viral target genes in Hodgkin lymphoma cells
A Dutton, CB Woodman, MB Chukwuma, JI Last, W Wei, M Vockerodt, KR Baumforth, JR Flavell, M Rowe, AM Taylor, LS Young, PG Murray
Blood 2006
A rapamycin derivative (everolimus) controls proliferation through down-regulation of truncated CCAAT enhancer binding protein {beta} and NF-{kappa}B activity in Hodgkin and anaplastic large cell lymphomas
F Jundt, N Raetzel, C Müller, CF Calkhoven, K Kley, S Mathas, A Lietz, A Leutz, B Dörken
Blood 2005
Immunobiology and Pathophysiology of Hodgkin Lymphomas
S Poppema
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program 2005
Role of nuclear factor-kappa B in melanoma
KI Amiri, A Richmond
Cancer metastasis reviews 2005
NF-κB and FLIP in arsenic trioxide (ATO)-induced apoptosis in myelodysplastic syndromes (MDSs)
DM Kerbauy, V Lesnikov, N Abbasi, S Seal, B Scott, HJ Deeg
Blood 2005
Autocrine- and paracrine-activated receptor tyrosine kinases in classic Hodgkin lymphoma
C Renné, K Willenbrock, R Küppers, ML Hansmann, A Bräuninger
Blood 2005
Viruses and lymphoma
MK Gandhi, R Khanna
Pathology 2005
Insights into the multistep transformation process of lymphomas: IgH-associated translocations and tumor suppressor gene mutations in clonally related composite Hodgkin's and non-Hodgkin's lymphomas
R Schmitz, C Renné, R Rosenquist, M Tinguely, V Distler, F Menestrina, M Lestani, T Stankovic, B Austen, A Bräuninger, ML Hansmann, R Küppers
Leukemia 2005
Comparative animal models for the study of lymphohematopoietic tumors: strengths and limitations of present approaches
OA O'Connor, LE Toner, R Vrhovac, T Budak-ALpdogan, EA Smith, P Bergman
Leukemia & Lymphoma 2005
The biology of human lymphoid malignancies revealed by gene expression profiling
LM Staudt, S Dave
Advances in immunology 2005
Feverfew: weeding out the root of leukaemia
ML Guzman, CT Jordan
Expert Opinion on Biological Therapy 2005
LMP1 signaling and activation of NF-κB in LMP1 transgenic mice
NJ Thornburg, W Kulwichit, RH Edwards, KH Shair, KM Bendt, N Raab-Traub
Oncogene 2005
Problems and promises of targeted therapy for Hodgkin's lymphoma
D Re, RK Thomas, T Zander, V Diehl
Nature Clinical Practice Oncology 2005
Aberrant NF-κB2/p52 expression in Hodgkin/Reed–Sternberg cells and CD30-transformed rat fibroblasts
M Nonaka, R Horie, K Itoh, T Watanabe, N Yamamoto, S Yamaoka
Oncogene 2005
STAT3 is essential for Hodgkin lymphoma cell proliferation and is a target of tyrphostin AG17 which confers sensitization for apoptosis
U Holtick, M Vockerodt, D Pinkert, N Schoof, B Stürzenhofecker, N Kussebi, K Lauber, S Wesselborg, D Löffler, F Horn, L Trümper, D Kube
Leukemia 2005
Hodgkin's lymphoma cells are efficiently engrafted and tumor marker CD30 is expressed with constitutive nuclear factor-kappaB activity in unconditioned NOD/SCID/gammacnull mice
MZ Dewan, M Watanabe, S Ahmed, K Terashima, S Horiuchi, T Sata, M Honda, M Ito, T Watanabe, R Horie, N Yamamoto
Cancer Science 2005
Differential expression of NF-κB pathway genes among peripheral T-cell lymphomas
B Martínez-Delgado, M Cuadros, E Honrado, AR de la Parte, G Roncador, J Alves, JM Castrillo, C Rivas, J Benítez
Leukemia 2005
Pathologie des Hodgkin-Lymphoms
K Willenbrock, C Renné, A Bräuninger, ML Hansmann
Der Onkologe 2005
Germline mutations and polymorphisms in theNFKBIA gene in Hodgkin lymphoma
J Osborne, A Lake, FE Alexander, GM Taylor, RF Jarrett
International Journal of Cancer 2005
Grundlagen der molekularen Diagnostik und Therapie maligner Tumoren
PT Daniel, B Dörken
Der Internist 2005
Large B-cell lymphoma with Hodgkin's features
JF Garcia, M Mollejo, M Fraga, J Forteza, JA Muniesa, M Perez-Guillermo, C Perez-Seoane, T Rivera, P Ortega, MA Piris
Histopathology 2005
Glycoprotein Isolated fromSolanum nigrumL. Modulates the Apoptotic-Related Signals in 12-O-Tetradecanoylphorbol 13-Acetate-Stimulated MCF-7 Cells
KS Heo, KT Lim
Journal of Medicinal Food 2005
Expression of the tumor necrosis factor receptor—associated factors 1 and 2 and regulation of the nuclear factor—kB antiapoptotic activity in human gliomas
A Conti, MH Aguennouz, DL Torre, S Cardali, FF Angileri, C Buemi, C Tomasello, DG Iacopino, D D'Avella, G Vita, F Tomasello
Journal of Neurosurgery 2005
The Hodgkin and Reed/Sternberg cell
R Küppers, ML Hansmann
The International Journal of Biochemistry & Cell Biology 2005
Glycoprotein Isolated fromSolanum nigrumL. Kills HT-29 Cells Through Apoptosis
KT Lim
Journal of Medicinal Food 2005
Inhibition of NF-κB activity by BAY 11-7082 increases apoptosis in multidrug resistant leukemic T-cell lines
MG García, L Alaniz, EC Lopes, G Blanco, SE Hajos, E Alvarez
Leukemia Research 2005
Chemosensitization and Radiosensitization of Tumors by Plant Polyphenols
AK Garg, TA Buchholz, BB Aggarwal
Antioxidants & Redox Signaling 2005
Immunosuppression by Combined Use of Cyclosporine and Resveratrol in a Rat Liver Transplantation Model
SL Wu, CE Pan, L Yu, KW Meng
Transplantation Proceedings 2005
Resveratrol prolongs allograft survival after liver transplantation in rats
SL Wu
World journal of gastroenterology : WJG 2005
Impact of Latent Epstein-Barr Virus Infection on Outcome in Children and Adolescents With Hodgkin's Lymphoma
A Claviez, M Tiemann, H Lüders, M Krams, R Parwaresch, G Schellong, W Dörffel
Journal of Clinical Oncology 2005
NFκB-dependent Down-regulation of Tumor Necrosis Factor Receptor-associated Proteins Contributes to Interleukin-1-mediated Enhancement of Ultraviolet B-induced Apoptosis
B Pöppelmann, K Klimmek, E Strozyk, R Voss, T Schwarz, D Kulms
The Journal of biological chemistry 2005
Fucoidan Extracted From Cladosiphon Okamuranus Tokida Induces Apoptosis of Human T-Cell Leukemia Virus Type 1-Infected T-Cell Lines and Primary Adult T-Cell Leukemia Cells
K Haneji, T Matsuda, M Tomita, H Kawakami, K Ohshiro, JN Uchihara, M Masuda, N Takasu, Y Tanaka, T Ohta, N Mori
Nutrition and Cancer 2005
Apoptotic Pathways as Targets for Novel Therapies in Cancer and Other Diseases
M Los, SB Gibson
2005
15-Deoxy-Δ12,14-prostaglandin J2 induces apoptosis in human malignant B cells: an effect associated with inhibition of NF-κB activity and down-regulation of antiapoptotic proteins
R Piva, P Gianferretti, A Ciucci, R Taulli, G Belardo, MG Santoro
Blood 2005
From Hodgkin disease to Hodgkin lymphoma: biologic insights and therapeutic potential
D Re, RK Thomas, K Behringer, V Diehl
Blood 2005
Elevated NF-κB p50 complex formation and Bcl-3 expression in classical Hodgkin, anaplastic large-cell, and other peripheral T-cell lymphomas
S Mathas, K Jöhrens, S Joos, A Lietz, F Hummel, M Janz, F Jundt, I Anagnostopoulos, K Bommert, P Lichter, H Stein, C Scheidereit, B Dörken
Blood 2005
Activation of Src kinase Lyn by the Kaposi sarcoma–associated herpesvirus K1 protein: implications for lymphomagenesis
O Prakash, OR Swamy, X Peng, ZY Tang, L Li, JE Larson, JC Cohen, J Gill, G Farr, S Wang, F Samaniego
Blood 2005
[Basics of molecular diagnostics and therapy of malignant tumors].
Daniel PT, Dörken B
Der Internist 2005
Resveratrol prolongs allograft survival after liver transplantation in rats.
Wu SL, Yu L, Meng KW, Ma ZH, Pan CE
World Journal of Gastroenterology 2005
Hodgkin's lymphoma cells are efficiently engrafted and tumor marker CD30 is expressed with constitutive nuclear factor‐κB activity in unconditioned NOD/SCID/γcnull mice
Dewan MZ, Watanabe M, Ahmed S, Terashima K, Horiuchi S, Sata T, Honda M, Ito M, Watanabe T, Horie R, Yamamoto N
Cancer Science 2005
NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression
Margit A. Huber, Ninel Azoitei, Bernd Baumann, Stefan Grünert, Andreas Sommer, Hubert Pehamberger, Norbert Kraut, Hartmut Beug, Thomas Wirth
Journal of Clinical Investigation 2004
Aspirin and the Risk of Hodgkin's Lymphoma in a Population-Based Case-Control Study
ET Chang, T Zheng, EG Weir, M Borowitz, RB Mann, D Spiegelman, NE Mueller
JNCI Journal of the National Cancer Institute 2004
Bystander Cells and Prognosis in Hodgkin Lymphoma
D Molin
Upsala Journal of Medical Sciences 2004
Expression of the cellular FLICE-inhibitory protein (c-FLIP) protects Hodgkin's lymphoma cells from autonomous Fas-mediated death
A Dutton, JD O'Neil, AE Milner, GM Reynolds, J Starczynski, J Crocker, LS Young, PG Murray
Proceedings of the National Academy of Sciences 2004
Apoptosis induced by the histone deacetylase inhibitor FR901228 in human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells
N Mori, T Matsuda, M Tadano, T Kinjo, Y Yamada, K Tsukasaki, S Ikeda, Y Yamasaki, Y Tanaka, T Ohta, T Iwamasa, M Tomonaga, N Yamamoto
Journal of virology 2004
Epstein-Barr virus-associated Hodgkin's lymphoma
MK Gandhi, JT Tellam, R Khanna
British Journal of Haematology 2004
Part I: Hodgkin's lymphoma—molecular biology of Hodgkin and Reed-Sternberg cells
RK Thomas, D Re, J Wolf, V Diehl
The Lancet Oncology 2004
L-ascorbic acid represses constitutive activation of NF-?B and COX-2 expression in human acute myeloid leukemia, HL-60
SS Han, K Kim, ER Hahm, SJ Lee, YJ Surh, HK Park, WS Kim, CW Jung, MH Lee, K Park, JH Yang, SS Yoon, NH Riordan, HD Riordan, BF Kimler, CH Park, JH Lee, S Park
Journal of Cellular Biochemistry 2004
Nuclear factor-KappaB modulation as a therapeutic approach in hematologic malignancies
A Panwalkar, S Verstovsek, F Giles
Cancer 2004
Proliferation profile of classical Hodgkin's lymphomas. Increased expression of the protein cyclin D2 in Hodgkin's and Reed–Sternberg cells
M Bai, E Tsanou, NJ Agnantis, S Kamina, C Grepi, K Stefanaki, D Rontogianni, V Galani, P Kanavaros
Modern Pathology 2004
Abnormal PcG protein expression in Hodgkin's lymphoma. Relation with E2F6 and NFκB transcription factors
M Sánchez-Beato, E Sánchez, JF García, A Pérez-Rosado, MC Montoya, M Fraga, MJ Artiga, M Navarrete, V Abraira, M Morente, M Esteller, H Koseki, M Vidal, MA Piris
The Journal of Pathology 2004
A 150-kDa glycoprotein isolated from Solanum nigrum L. has cytotoxic and apoptotic effects by inhibiting the effects of protein kinase C alpha, nuclear factor-kappa B and inducible nitric oxide in HCT-116 cells
SJ Lee, PS Oh, JH Ko, K Lim, KT Lim
Cancer Chemotherapy and Pharmacology 2004
In vitro EBV-infected subline of KMH2, derived from Hodgkin lymphoma, expresses only EBNA-1, while CD40 ligand and IL-4 induce LMP-1 but not EBNA-2
LL Kis, J Nishikawa, M Takahara, N Nagy, L Matskova, K Takada, PG Elmberger, A Ohlsson, G Klein, E Klein
International Journal of Cancer 2004
Mutational analysis of the IkappaBalpha gene in activated B cell-like diffuse large B-cell lymphoma
RK Thomas, C Wickenhauser, S Tawadros, V Diehl, R Kuppers, J Wolf, R Schmitz
British Journal of Haematology 2004
Differential Expression Patterns of c-REL Protein in Classic and Nodular Lymphocyte Predominant Hodgkin Lymphoma
Q Xiao, N Shen, CV Hedvat, CH Moskowitz, LK Sussman, DA Filippa, AD Zelenetz, J Houldsworth, RS Chaganti, J Teruya-Feldstein
Applied Immunohistochemistry & Molecular Morphology 2004
A Beginner's Guide to NF-κB Signaling Pathways
S Delhalle, R Blasius, M Dicato, M Diederich
Annals of the New York Academy of Sciences 2004
Expression of constitutively active Nuclear-κB RelA transcription factor in blasts of acute myeloid leukemia
CE Bueso-Ramos, FC Rocha, S Shishodia, LJ Medeiros, HM Kantarjian, S Vadhan-Raj, Z Estrov, TL Smith, MH Nguyen, BB Aggarwal
Human Pathology 2004
Update on the Proteasome Inhibitor Bortezomibin Hematologic Malignancies
A Goy, F Gilles
Clinical Lymphoma & Myeloma 2004
Regulation of glutathione S-transferase P1-1 gene expression by NF-kappaB in tumor necrosis factor alpha-treated K562 leukemia cells
F Morceau, A Duvoix, S Delhalle, M Schnekenburger, M Dicato, M Diederich
Biochemical Pharmacology 2004
Endostatin's Antiangiogenic Signaling Network
A Abdollahi, P Hahnfeldt, C Maercker, HJ Gröne, J Debus, W Ansorge, J Folkman, L Hlatky, PE Huber
Molecular Cell 2004
Nuclear factor-kappaB p65 (RelA) transcription factor is constitutively activated in human colorectal carcinoma tissue
Liang-Liang Yu, Hong-Gang Yu, Jie-Ping Yu, He-Sheng Luo, Xi-Ming Xu, Jun-Hua Li
World journal of gastroenterology : WJG 2004
Nuclear factor-kB p65 (RelA) transcription factor is constitutively activated in human colorectal carcinoma tissue
LL Yu
World journal of gastroenterology : WJG 2004
c-FLIP Mediates Resistance of Hodgkin/Reed-Sternberg Cells to Death Receptor–induced Apoptosis
S Mathas, A Lietz, I Anagnostopoulos, F Hummel, B Wiesner, M Janz, F Jundt, B Hirsch, K Jöhrens-Leder, HP Vornlocher, K Bommert, H Stein, B Dörken
Journal of Experimental Medicine 2004
A Cellular UDP-glucose Deficiency Causes Overexpression of Glucose/Oxygen-regulated Proteins Independent of the Endoplasmic Reticulum Stress Elements
M Flores-Diaz, JC Higuita, I Florin, T Okada, P Pollesello, T Bergman, M Thelestam, K Mori, A Alape-Giron
The Journal of biological chemistry 2004
Oncogenic and Anti-apoptotic Activity of NF-κB in Human Thyroid Carcinomas
F Pacifico, C Mauro, C Barone, E Crescenzi, S Mellone, M Monaco, G Chiappetta, G Terrazzano, D Liguoro, P Vito, E Consiglio, S Formisano, A Leonardi
The Journal of biological chemistry 2004
Considerations for Targeting Malignant Stem Cells in Leukemia
ML Guzman, CT Jordan
Cancer control : journal of the Moffitt Cancer Center 2004
Antitumor effects of bortezomib (PS-341) on primary effusion lymphomas
J An, Y Sun, M Fisher, MB Rettig
Leukemia 2004
Expression of SCC-S2, an antiapoptotic molecule, correlates with enhanced proliferation and tumorigenicity of MDA-MB 435 cells
D Kumar, P Gokhale, C Broustas, D Chakravarty, I Ahmad, U Kasid
Oncogene 2004
NF-κB Family Proteins Participate in Multiple Steps of Hematopoiesis through Elimination of Reactive Oxygen Species
S Nakata, I Matsumura, H Tanaka, S Ezoe, Y Satoh, J Ishikawa, T Era, Y Kanakura
The Journal of biological chemistry 2004
Sensitization of Taxol-induced Apoptosis by Curcumin Involves Down-regulation of Nuclear Factor-κB and the Serine/Threonine Kinase Akt and Is Independent of Tubulin Polymerization
SV Bava, VT Puliappadamba, A Deepti, A Nair, D Karunagaran, RJ Anto
The Journal of biological chemistry 2004
Identification and Characterization of the IKKα Promoter: POSITIVE AND NEGATIVE REGULATION BY ETS-1 AND p53, RESPECTIVELY
L Gu, N Zhu, HW Findley, WG Woods, M Zhou
The Journal of biological chemistry 2004
Tumor necrosis factor α sensitizes malignant cells to chemotherapeutic drugs via the mitochondrial apoptosis pathway independently of caspase-8 and NF-κB
K Schmelz, T Wieder, I Tamm, A Müller, F Essmann, CC Geilen, K Schulze-Osthoff, B Dörken, PT Daniel
Oncogene 2004
Inhibition of NFκB Increases the Efficacy of Cisplatin in in Vitro and in Vivo Ovarian Cancer Models
S Mabuchi, M Ohmichi, Y Nishio, T Hayasaka, A Kimura, T Ohta, M Saito, J Kawagoe, K Takahashi, N Yada-Hashimoto, M Sakata, T Motoyama, H Kurachi, K Tasaka, Y Murata
The Journal of biological chemistry 2004
Hematopathology in Oncology
WG Finn, LA Peterson
2004
Cancer Immunotherapy at the Crossroads
JH Finke, RM Bukowski
2004
Molecular Signatures of Lymphoma
KJ Savage, RD Gascoyne
International Journal of Hematology 2004
Signal Transduction in Cancer
DA Frank
2004
Molecular Targeting and Signal Transduction
R Kumar
2004
Regulation of Constitutive p50/c-Rel Activity via Proteasome Inhibitor-Resistant IκBα Degradation in B Cells
S O'Connor, SD Shumway, IJ Amanna, CE Hayes, S Miyamoto
Molecular and cellular biology 2004
Induction of Cell Cycle Arrest and Apoptosis by the Proteasome Inhibitor PS-341 in Hodgkin Disease Cell Lines Is Independent of Inhibitor of Nuclear Factor-κB Mutations or Activation of the CD30, CD40, and RANK Receptors
B Zheng, GV Georgakis, Y Li, A Bharti, D McConkey, BB Aggarwal, A Younes
Clinical cancer research 2004
Tumor Stroma Interactions Induce Chemoresistance in Pancreatic Ductal Carcinoma Cells Involving Increased Secretion and Paracrine Effects of Nitric Oxide and Interleukin-1β
S Müerköster, K Wegehenkel, A Arlt, M Witt, B Sipos, ML Kruse, T Sebens, G Klöppel, H Kalthoff, UR Fölsch, H Schäfer
Cancer research 2004
Identification of Hodgkin and Reed-Sternberg cell-specific genes by gene expression profiling
Ralf Küppers, Ulf Klein, Ines Schwering, Verena Distler, Andreas Bräuninger, Giorgio Cattoretti, Yuhai Tu, Gustavo A. Stolovitzky, Andrea Califano, Martin-Leo Hansmann, Riccardo Dalla-Favera
Journal of Clinical Investigation 2003
NF-kappaB and virus infection: who controls whom
MG Santoro, A Rossi, C Amici
The EMBO Journal 2003
Jesterone Dimer, a Synthetic Derivative of the Fungal Metabolite Jesterone, Blocks Activation of Transcription Factor Nuclear Factor κB by Inhibiting the Inhibitor of κB Kinase
MC Liang, S Bardhan, C Li, EA Pace, JA Porco, TD Gilmore
Molecular pharmacology 2003
Mutant human cells with constitutive activation of NF-kappaB
SS Sathe, N Sizemore, X Li, K Vithalani, M Commane, SM Swiatkowski, GR Stark
Proceedings of the National Academy of Sciences 2003
Inhibition of NF-κB essentially contributes to arsenic-induced apoptosis
S Mathas, A Lietz, M Janz, M Hinz, F Jundt, C Scheidereit, K Bommert, B Dörken
Blood 2003
Inhibition of Constitutive NF-κB Activation in Mantle Cell Lymphoma B Cells Leads to Induction of Cell Cycle Arrest and Apoptosis
LV Pham, AT Tamayo, LC Yoshimura, P Lo, RJ Ford
Journal of immunology (Baltimore, Md. : 1950) 2003
Potentiation of tumour apoptosis by human growth hormone via glutathione production and decreased NF-kappaB activity
C Cherbonnier, O Déas, G Carvalho, G Vassal, A Dürrbach, A Haeffner, B Charpentier, J Bénard, F Hirsch
British Journal of Cancer 2003
Epstein-Barr Virus (EBV) LMP2A induces alterations in gene transcription similar to those observed in Reed-Sternberg cells of Hodgkin lymphoma
T Portis, P Dyck, R Longnecker
Blood 2003
Multiple effects of α1-antitrypsin on breast carcinoma MDA-MB 468 cell growth and invasiveness
I Zelvyte, S Lindgren, S Janciauskiene
European Journal of Cancer Prevention 2003
Kaposi's sarcoma-associated herpesvirus-infected primary effusion lymphoma has a plasma cell gene expression profile
RG Jenner, K Maillard, N Cattini, RA Weiss, C Boshoff, R Wooster, P Kellam
Proceedings of the National Academy of Sciences 2003
AP-1 mediated relief of repressive activity of the CD30 promoter microsatellite in Hodgkin and Reed-Sternberg cells
M Watanabe, Y Ogawa, K Ito, M Higashihara, ME Kadin, LJ Abraham, T Watanabe, R Horie
The American Journal of Pathology 2003
Profiling of Hodgkin's lymphoma cell line L1236 and germinal center B cells: identification of Hodgkin's lymphoma-specific genes
I Schwering, A Bräuninger, V Distler, J Jesdinsky, V Diehl, ML Hansmann, K Rajewsky, R Küppers
Molecular Medicine 2003
Epstein-Barr virus encoded latent membrane protein 1 (LMP1) and TNF receptor associated factors (TRAF): colocalisation of LMP1 and TRAF1 in primary EBV infection and in EBV associated Hodgkin lymphoma
G Siegler, E Kremmer, R Gonnella, G Niedobitek
Molecular pathology : MP 2003
NF-κB activation in cancer: a challenge for ubiquitination- and proteasome-based therapeutic approach
S Amit, Y Ben-Neriah
Seminars in Cancer Biology 2003
Inhibitory effects of the ginsenoside Rg3 on phorbol ester-induced cyclooxygenase-2 expression, NF-κB activation and tumor promotion
YS Keum, SS Han, KS Chun, KK Park, JH Park, SK Lee, YJ Surh
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 2003
Differential expression and function of A20 and TRAF1 in Hodgkin lymphoma and anaplastic large cell lymphoma and their induction by CD30 stimulation
H D�rkop, B Hirsch, C Hahn, HD Foss, H Stein
The Journal of Pathology 2003
Inactivating I kappa B epsilon mutations in Hodgkin/Reed-Sternberg cells
F Emmerich, S Theurich, M Hummel, A Haeffker, MS Vry, K D�hner, K Bommert, H Stein, B D�rken
The Journal of Pathology 2003
High-throughput tissue microarray analysis of G1-cyclin alterations in classical Hodgkin's lymphoma indicates overexpression of cyclin E1
A Tzankov, A Zimpfer, A Lugli, J Krugmann, P Went, P Schraml, R Maurer, S Ascani, S Pileri, S Geley, S Dirnhofer
The Journal of Pathology 2003
Hodgkin disease immunopathogenesis: long-standing questions, recent answers, further directions
T Papadaki, K Stamatopoulos
Trends in Immunology 2003
The Molecular Basis for the Generation of Hodgkin and Reed-Sternberg Cells in Hodgkin’s Lymphoma
IS Lee, SH Kim, HG Song, SH Park
International Journal of Hematology 2003
Hodgkin’s Lymphoma and CD30 Signal Transduction
R Horie, M Higashihara, T Watanabe
International Journal of Hematology 2003
NF-κB in cancer: a marked target
A Lin, M Karin
Seminars in Cancer Biology 2003
Evolution of classic Hodgkin lymphoma in correlation to changes in the lymphoid organ structure of vertebrates
V Seitz, M Hummel, J Walter, H Stein
Developmental & Comparative Immunology 2003
Death receptor-induced cell death in prostate cancer
NV Guseva, AF Taghiyev, OW Rokhlin, MB Cohen
Journal of Cellular Biochemistry 2003
Nuclear Transcription Factor-kappaB in Hodgkin's Disease
A Younes, A Garg, BB Aggarwal
Leukemia & Lymphoma 2003
Involvement of nuclear transcription factor-κB in low-dose doxorubicin-induced drug resistance of cervical carcinoma cells
PY Yeh, SE Chuang, KH Yeh, YC Song, AL Cheng
Biochemical Pharmacology 2003
Viral Infections and Treatment: Pathogenesis and Treatment
N Raab-Traub, S Kenney
Viral Infections and Treatment: Pathogenesis and Treatment 2003
Overcoming Drug Resistance in Multiple Myeloma: The Emergence of Therapeutic Approaches to Induce Apoptosis
HH Yang, MH Ma, RA Vescio, JR Berenson
Journal of Clinical Oncology 2003
NF-κB/Rel-mediated regulation of apoptosis in hematologic malignancies and normal hematopoietic progenitors
MC Turco, MF Romano, A Petrella, R Bisogni, P Tassone, S Venuta
Leukemia 2003
To be, or not to be: NF-κB is the answer – role of Rel/NF-κB in the regulation of apoptosis
J Kucharczak, MJ Simmons, Y Fan, C Gélinas
Oncogene 2003
Phosphorylation of PPAR? via active ERK1/2 leads to its physical association with p65 and inhibition of NF-??
F Chen, M Wang, JP O'Connor, M He, T Tripathi, LE Harrison
Journal of Cellular Biochemistry 2003
Mitogenic and antiapoptotic role of constitutive NF-?B/Rel activity in pancreatic cancer
S Liptay, CK Weber, L Ludwig, M Wagner, G Adler, RM Schmid
International Journal of Cancer 2003
Senescence, apoptosis and therapy — cutting the lifelines of cancer
CA Schmitt
Nature Reviews Cancer 2003
Osteopontin Stimulates Cell Motility and Nuclear Factor κB-mediated Secretion of Urokinase Type Plasminogen Activator through Phosphatidylinositol 3-Kinase/Akt Signaling Pathways in Breast Cancer Cells
R Das, GH Mahabeleshwar, GC Kundu
The Journal of biological chemistry 2003
Divergent C-terminal transactivation domains of Rel/NF-κB proteins are critical determinants of their oncogenic potential in lymphocytes
Y Fan, B Rayet, C Gélinas
Oncogene 2003
NF-κB transcription factor induces drug resistance through MDR1 expression in cancer cells
M Bentires-Alj, V Barbu, M Fillet, A Chariot, B Relic, N Jacobs, J Gielen, MP Merville, V Bours
Oncogene 2003
NF-κB2/p100 induces Bcl-2 expression
P Viatour, M Bentires-Alj, A Chariot, V Deregowski, L Leval, MP Merville, V Bours
Leukemia 2003
NF-κ B Promotes Breast Cancer Cell Migration and Metastasis by Inducing the Expression of the Chemokine Receptor CXCR4
G Helbig, KW Christopherson, P Bhat-Nakshatri, S Kumar, H Kishimoto, KD Miller, HE Broxmeyer, H Nakshatri
The Journal of biological chemistry 2003
PSK-mediated NF-κB inhibition augments docetaxel-induced apoptosis in human pancreatic cancer cells NOR-P1
H Zhang, T Morisaki, C Nakahara, H Matsunaga, N Sato, F Nagumo, J Tadano, M Katano
Oncogene 2003
Epstein–Barr virus and oncogenesis: from latent genes to tumours
LS Young, PG Murray
Oncogene 2003
Transfection of a dominant-negative mutant NF-kB inhibitor (IkBm) represses p53-dependent apoptosis in acute lymphoblastic leukemia cells: interaction of IkBm and p53
M Zhou, L Gu, N Zhu, WG Woods, HW Findley
Oncogene 2003
Molekularmedizinische Grundlagen von hämatologischen Neoplasien
D Ganten, K Ruckpaul, B Schlegelberger, C Fonatsch
2003
Profiling of Hodgkin’s Lymphoma Cell Line L1236 and Germinal Center B Cells: Identification of Hodgkin’s Lymphoma-specific Genes
I Schwering, A Bräuninger, V Distler, J Jesdinsky, V Diehl, ML Hansmann, K Rajewsky, R Küppers
Molecular Medicine 2003
Nuclear Factor кB
R Beyaert
2003
Mechanisms in Carcinogenesis and Cancer Prevention
HU Vainio, EK Hietanen
2003
Latent Membrane Protein 1, Tumor Necrosis Factor Receptor–Associated Factor (TRAF) 1, TRAF-2, TRAF-3, and Nuclear Factor Kappa B Expression in Posttransplantation Lymphoproliferative Disorders
P Ramalingam, WS Chu, R Tubbs, L Rybicki, J Pettay, ED Hsi
Archives of pathology & laboratory medicine 2003
Lysyl Oxidase Inhibits Ras-Mediated Transformation by Preventing Activation of NF-κB
S Jeay, S Pianetti, HM Kagan, GE Sonenshein
Molecular and cellular biology 2003
Gains of 2p involving the REL locus correlate with nuclear c-Rel protein accumulation in neoplastic cells of classical Hodgkin lymphoma
TF Barth, JI Martin-Subero, S Joos, CK Menz, C Hasel, G Mechtersheimer, RM Parwaresch, P Lichter, R Siebert, P Möller
Blood 2003
Hodgkin's lymphoma and CD30 signal transduction.
Horie R, Higashihara M, Watanabe T
International Journal of Hematology 2003
The molecular basis for the generation of Hodgkin and Reed-Sternberg cells in Hodgkin's lymphoma.
Lee IS, Kim SH, Song HG, Park SH
International Journal of Hematology 2003
Nuclear Factor κB–dependent Gene Expression Profiling of Hodgkin's Disease Tumor Cells, Pathogenetic Significance, and Link to Constitutive Signal Transducer and Activator of Transcription 5a Activity
M Hinz, P Lemke, I Anagnostopoulos, C Hacker, D Krappmann, S Mathas, B Dörken, M Zenke, H Stein, C Scheidereit
Journal of Experimental Medicine 2002
Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B
S Mathas, M Hinz, I Anagnostopoulos, D Krappmann, A Lietz, F Jundt, K Bommert, F Mechta-Grigoriou, H Stein, B Dörken, C Scheidereit
The EMBO Journal 2002
Cytoplasmic aggregation of TRAF2 and TRAF5 proteins in the Hodgkin-Reed-Sternberg cells
R Horie, T Watanabe, K Ito, Y Morisita, M Watanabe, T Ishida, M Higashihara, M Kadin, T Watanabe
The American Journal of Pathology 2002
Constitutive expression of c-FLIP in Hodgkin and Reed-Sternberg cells
RK Thomas, A Kallenborn, C Wickenhauser, JL Schultze, A Draube, M Vockerodt, D Re, V Diehl, J Wolf
The American Journal of Pathology 2002
Interleukin 6 expression by Hodgkin/Reed-Sternberg cells is associated with the presence of 'B' symptoms and failure to achieve complete remission in patients with advanced Hodgkin's disease
GM Reynolds, LJ Billingham, LJ Gray, JR Flavell, S Najafipour, J Crocker, P Nelson, LS Young, PG Murray
British Journal of Haematology 2002
NF-κB as a therapeutic target in cancer
RZ Orlowski, AS Baldwin
Trends in Molecular Medicine 2002
Growth hormone can act as a cytokine controlling survival and proliferation of immune cells: new insights into signaling pathways
S Jeay, GE Sonenshein, MC Postel-Vinay, PA Kelly, E Baixeras
Molecular and Cellular Endocrinology 2002
Rel/NF-κB/IκB signal transduction in the generation and treatment of human cancer
T Gilmore, ME Gapuzan, D Kalaitzidis, D Starczynowski
Cancer Letters 2002
Antitumor Mechanisms of Oligodeoxynucleotides with CpG and PolyG Motifs in Murine Prostate Cancer Cells: Decrease of NF-κB and AP-1 Binding Activities and Induction of Apoptosis
W Shen, M Waldschmidt, X Zhao, T Ratliff, AM Krieg
Antisense and Nucleic Acid Drug Development 2002
Anti-tumor promoting potential of selected spice ingredients with antioxidative and anti-inflammatory activities: a short review
YJ Surh
Food and Chemical Toxicology 2002
NF-kappaB in cancer: from innocent bystander to major culprit
M Karin, Y Cao, FR Greten, ZW Li
Nature Reviews Cancer 2002
Anticancer Drug Development
E Solary, N Droin, O Sordet, C Rebe, R Filomenko, A Wotawa, S Plenchette, P Ducoroy
Anticancer Drug Development 2002
Nuclear factor-kappa B and cancer: its role in prevention and therapy
AC Bharti, BB Aggarwal
Biochemical Pharmacology 2002
TNF-α Protects Human Primary Articular Chondrocytes from Nitric Oxide-Induced Apoptosis Via Nuclear Factor-κB
B Relić, M Bentires-Alj, C Ribbens, N Franchimont, PA Guerne, V Benoît, MP Merville, V Bours, MG Malaise
Laboratory Investigation 2002
Identification of cytokine-induced nuclear factor-kappaB target genes in ovarian and breast cancer cells
V Deregowski, S Delhalle, V Benoit, V Bours, MP Merville
Biochemical Pharmacology 2002
Basal levels and patterns of anticancer drug-induced activation of nuclear factor-κB (NF-κB), and its attenuation by tamoxifen, dexamethasone, and curcumin in carcinoma cells
SE Chuang, PY Yeh, YS Lu, GM Lai, CM Liao, M Gao, AL Cheng
Biochemical Pharmacology 2002
Stable Inhibition of NF-κB in Salivary Gland Cells Does Not Enhance Sensitivity to TNF-α-Induced Apoptosis Due to Upregulation of TRAF-1 Expression
K Aota, M Azuma, T Tamatani, T Yamashita, Y Ashida, M Sato
Experimental Cell Research 2002
Focus on lymphomas
LM Staudt, WH Wilson
Cancer Cell 2002
A CD40 Signalosome Anchored in Lipid Rafts Leads to Constitutive Activation of NF-κB and Autonomous Cell Growth in B Cell Lymphomas
LV Pham, AT Tamayo, LC Yoshimura, P Lo, N Terry, PS Reid, RJ Ford
Immunity 2002
Hodgkin's lymphoma cell lines are characterized by frequent aberrations on chromosomes 2p and 9p including REL and JAK2: Aberrations in Hodgkin's Lymphoma Cell Lines
S Joos, M Granzow, H Holtgreve-Grez, R Siebert, L Harder, JI Martín-Subero, J Wolf, M Adamowicz, TF Barth, P Lichter, A Jauch
International Journal of Cancer 2002
Identification of signal transduction pathways involved in constitutive NF-κB activation in breast cancer cells
P Bhat-Nakshatri, CJ Sweeney, H Nakshatri
Oncogene 2002
An NAD(P)H oxidase regulates growth and transcription in melanoma cells
SS Brar, TP Kennedy, AB Sturrock, TP Huecksteadt, MT Quinn, AR Whorton, JR Hoidal
American journal of physiology. Cell physiology 2002
Nuclear transcription factor-κB as a target for cancer drug development
A Garg, BB Aggarwal
Leukemia 2002
Increased IκB kinase activity is associated with activated NF-κB in acute myeloid blasts
B Baumgartner, M Weber, M Quirling, C Fischer, S Page, M Adam, C von Schilling, C Waterhouse, C Schmid, D Neumeier, K Brand
Leukemia 2002
Unique molecular and cellular features of acute myelogenous leukemia stem cells
CT Jordan
Leukemia 2002
Silibinin inhibits constitutive and TNFα-induced activation of NF-κB and sensitizes human prostate carcinoma DU145 cells to TNFα-induced apoptosis
S Dhanalakshmi, RP Singh, C Agarwal, R Agarwal
Oncogene 2002
Common and differential chemokine expression patterns in rs cells of NLP, EBV positive and negative classical hodgkin lymphomas
EM Maggio, AV Berg, L Visser, A Diepstra, J Kluiver, R Emmens, S Poppema
International Journal of Cancer 2002
Ligand-independent signaling by overexpressed CD30 drives NF-κB activation in Hodgkin–Reed-Sternberg cells
R Horie, T Watanabe, Y Morishita, K Ito, T Ishida, Y Kanegae, I Saito, M Higashihara, S Mori, ME Kadin, T Watanabe
Oncogene 2002
VCP (p97) regulates NFkappaB signaling pathway, which is important for metastasis of osteosarcoma cell line
Tatsuya Asai, Yasuhiko Tomita, Shin-ichi Nakatsuka, Yoshihiko Hoshida, Akira Myoui, Hideki Yoshikawa, Katsuyuki Aozasa
Japanese journal of cancer research : Gann 2002
Tissue inhibitor of metalloproteinases 1 is an autocrine and paracrine survival factor, with additional immune-regulatory functions, expressed by Hodgkin/Reed-Sternberg cells
E Oelmann, H Herbst, M Zühlsdorf, O Albrecht, A Nolte, C Schmitmann, O Manzke, V Diehl, H Stein, WE Berdel
Blood 2002
The role of cytokines in classical Hodgkin lymphoma
BF Skinnider, TW Mak
Blood 2002
Biology of Hodgkin's lymphoma
R Küppers, I Schwering, A Bräuninger, K Rajewsky, ML Hansmann
Annals of Oncology 2002
High numbers of active caspase 3–positive Reed-Sternberg cells in pretreatment biopsy specimens of patients with Hodgkin disease predict favorable clinical outcome
DF Dukers, CJ Meijer, RL ten Berge, W Vos, GJ Ossenkoppele, JJ Oudejans
Blood 2002
Activated Notch1 signaling promotes tumor cell proliferation and survival in Hodgkin and anaplastic large cell lymphoma
F Jundt, I Anagnostopoulos, R Förster, S Mathas, H Stein, B Dörken
Blood 2002
Classical Hodgkin lymphoma is characterized by recurrent copy number gains of the short arm of chromosome 2
S Joos, CK Menz, G Wrobel, R Siebert, S Gesk, S Ohl, G Mechtersheimer, L Trümper, P Möller, P Lichter, TF Barth
Blood 2002
Fas Resistance of Leukemic Eosinophils Is Due to Activation of NF-κB by Fas Ligation
Y Qin, B Camoretti-Mercado, L Blokh, CG Long, FD Ko, KJ Hamann
Journal of immunology (Baltimore, Md. : 1950) 2002
VCP (p97) Regulates NFKB Signaling Pathway, Which Is Important for Metastasis of Osteosarcoma Cell Line
Asai T, Tomita Y, Nakatsuka S, Hoshida Y, Myoui A, Yoshikawa H, Aozasa K
Japanese journal of cancer research : Gann 2002
Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kB
Albert Baldwin
Journal of Clinical Investigation 2001
Antiproliferative Effects of IFN-αCorrelate with the Downregulation of Nuclear Factor-κB in Human Burkitt Lymphoma Daudi Cells
PC Rath, BB Aggarwal
Journal of Interferon & Cytokine Research 2001
relA over-expression reduces tumorigenicity and activates apoptosis in human cancer cells
A Ricca, A Biroccio, D Trisciuoglio, M Cippitelli, G Zupi, DD Bufalo
British Journal of Cancer 2001
Epstein-Barr virus LMP-1 natural sequence variants differ in their potential to activate cellular signaling pathways
CA Fielding, K Sandvej, A Mehl, P Brennan, M Jones, M Rowe
Journal of virology 2001
Loss of heterozygosity in the Hodgkin-Reed Sternberg cell line L1236
A Staratschek-Jox, RK Thomas, T Zander, N Massoudi, M Kornacker, J Bullerdiek, C Fonatsch, V Diehl, J Wolf
British Journal of Cancer 2001
Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-κB activation
YJ Surh, KS Chun, HH Cha, SS Han, YS Keum, KK Park, SS Lee
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 2001
High expression levels of nuclear factor ?B, I?B kinase ? and Akt kinase in squamous cell carcinoma of the oral cavity
H Nakayama, T Ikebe, M Beppu, K Shirasuna
Cancer 2001
Expression of the tumour necrosis factor receptor-associated factors 1 and 2 in Hodgkin's disease
PG Murray, JR Flavell, KR Baumforth, SM Toomey, D Lowe, J Crocker, RF Ambinder, LS Young
The Journal of Pathology 2001
The Reed-Sternberg cell in classical Hodgkin's disease
WC Chan
Hematological Oncology 2001
Analysis of expression of nuclear factor kappaB (NF-kappaB) in multiple myeloma: downregulation of NF-kappaB induces apoptosis
H Ni, M Ergin, Q Huang, JZ Qin, HM Amin, RL Martinez, S Saeed, K Barton, S Alkan
British Journal of Haematology 2001
Gingival Overgrowth as the Initial Paraneoplastic Manifestation of Hodgkin's Lymphoma in a Child. A Case Report
O Nicolatou-Galitis, T Papadaki, M Moshovi, JJ Kamma, CV Vliet-Constantinidou, C Tsoumakas, A Kattamis, F Tzortzatou-Stathopoulou
Journal of Periodontology 2001
Capsaicin suppresses phorbol ester-induced activation of NF-κB/Rel and AP-1 transcription factors in mouse epidermis
SS Han, YS Keum, HJ Seo, KS Chun, SS Lee, YJ Surh
Cancer Letters 2001
IKKα Provides an Essential Link between RANK Signaling and Cyclin D1 Expression during Mammary Gland Development
Y Cao, G Bonizzi, TN Seagroves, FR Greten, R Johnson, EV Schmidt, M Karin
Cell 2001
Ubiquitin proteasome pathway: implications and advances in cancer therapy
SA Shah, MW Potter, MP Callery
Surgical Oncology 2001
Her-2/neu overexpression induces NF-kappaB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IkappaB-alpha that can be inhibited by the tumor suppressor PTEN
S Pianetti, M Arsura, R Romieu-Mourez, RJ Coffey, GE Sonenshein
Oncogene 2001
Nuclear factor-κB is upregulated in colorectal cancer
DS Lind, SN Hochwald, J Malaty, S Rekkas, P Hebig, G Mishra, LL Moldawer, EM Copeland, S MacKay
Surgery 2001
Involvement of nuclear factor-kappa B (NF-κB) activation in mitogen-induced lymphocyte proliferation: inhibitory effects of lymphoproliferation by salicylates acting as NF-κB inhibitors
L Cavallini, MA Francesconi, F Zoccarato, A Alexandre
Biochemical Pharmacology 2001
Immunomodulatory activity of resveratrol: suppression of lymphocyte proliferation, development of cell-mediated cytotoxicity, and cytokine production
X Gao, YX Xu, N Janakiraman, RA Chapman, SC Gautam∗
Biochemical Pharmacology 2001
Constitutive Nuclear Factor κB Activity Is Required for Survival of Activated B Cell–like Diffuse Large B Cell Lymphoma Cells
RE Davis, KD Brown, U Siebenlist, LM Staudt
Journal of Experimental Medicine 2001
Reactive oxygen species from NAD(P)H:quinone oxidoreductase constitutively activate NF-κB in malignant melanoma cells
SS Brar, TP Kennedy, AR Whorton, AB Sturrock, TP Huecksteadt, AJ Ghio, JR Hoidal
American journal of physiology. Cell physiology 2001
Inhibition of the NF-κB transcription factor increases Bax expression in cancer cell lines
M Bentires-Alj, E Dejardin, P Viatour, CV Lint, B Froesch, JC Reed, MP Merville, V Bours
Oncogene 2001
Nuclear Factor-κB-inducible Death Effector Domain-containing Protein Suppresses Tumor Necrosis Factor-mediated Apoptosis by Inhibiting Caspase-8 Activity
Z You, H Ouyang, D Lopatin, PJ Polver, CY Wang
The Journal of biological chemistry 2001
Phosphatidylinositol 3-Kinase and NF-κB Regulate Motility of Invasive MDA-MB-231 Human Breast Cancer Cells by the Secretion of Urokinase-type Plasminogen Activator
D Sliva, MT Rizzo, D English
The Journal of biological chemistry 2001
High constitutive level of NF-κB is crucial for viability of adenocarcinoma cells
AS Smirnov, AS Ruzov, AV Budanov, AV Prokhortchouk, AV Ivanov, EB Prokhortchouk
Cell Death and Differentiation 2001
Characterization of NF-κB Expression in Hodgkin’s Disease: Inhibition of Constitutively Expressed NF-κB Results in Spontaneous Caspase-Independent Apoptosis in Hodgkin and Reed-Sternberg Cells
KF Izban, M Ergin, Q Huang, J Qin, RL Martinez, B Schnitzer, H Ni, BJ Nickoloff, S Alkan
Modern Pathology 2001
Murine embryonic fibroblasts lacking TC-PTP display delayed G1 phase through defective NF-κB activation
MJ Ibarra-Sánchez, J Wagner, MT Ong, C Lampron, ML Tremblay
Oncogene 2001
Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines
A Mukhopadhyay, C Bueso-Ramos, D Chatterjee, P Pantazis, BB Aggarwal
Oncogene 2001
Differential effects of Ras signaling through NFκB on skeletal myogenesis
N Mitin, AJ Kudla, SF Konieczny, EJ Taparowsky
Oncogene 2001
Epstein–Barr virus latent membrane protein-1 activates CD25 expression in lymphoma cells involving the NFκB pathway
M Vockerodt, H Tesch, D Kube
Genes and Immunity 2001
Leukocyte Recruitment, Endothelial Cell Adhesion Molecules, and Transcriptional Control
T Collins
2001
Signaling pathways activated by daunorubicin
G Laurent, JP Jaffrézou
Blood 2001
STAT3 is constitutively activated in Hodgkin cell lines
D Kube, U Holtick, M Vockerodt, T Ahmadi, B Haier, I Behrmann, PC Heinrich, V Diehl, H Tesch
Blood 2001
Nuclear factor-κB is constitutively activated in primitive human acute myelogenous leukemia cells
ML Guzman, SJ Neering, D Upchurch, B Grimes, DS Howard, DA Rizzieri, SM Luger, CT Jordan
Blood 2001
CD99 expression is positively regulated by Sp1 and is negatively regulated by Epstein-Barr virus latent membrane protein 1 through nuclear factor-κB
I Lee, MK Kim, EY Choi, A Mehl, KC Jung, MC Gil, M Rowe, SH Park
Blood 2001
The Role of NF-κB in TNF-Related Apoptosis-Inducing Ligand (TRAIL)-Induced Apoptosis of Melanoma Cells
AV Franco, XD Zhang, EV Berkel, JE Sanders, , WD Thomas, T Nguyen, P Hersey
Journal of immunology (Baltimore, Md. : 1950) 2001
Constitutive NF-κB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells
M Hinz, P Löser, S Mathas, D Krappmann, B Dörken, C Scheidereit
Blood 2001
The role of constitutive NF-kappaB activity in PC-3 human prostate cancer cell invasive behavior
P F Lindholm, J Bub, S Kaul, V B Shidham, A Kajdacsy-Balla
Clinical & Experimental Metastasis 2001
Selective activation of NF-kappa B subunits in human breast cancer: potential roles for NF-kappa B2/p52 and for Bcl-3
MA Sovak, RE Bellas, DW Kim, GJ Zanieski, AE Rogers, AM Traish, GE Sonenshein
Journal of Clinical Investigation 2000
Interaction between host T cells and Reed–Sternberg cells in Hodgkin lymphomas
S Poppema, A Berg
Seminars in Cancer Biology 2000
Kinase Inhibitors in Cancer Therapy
H Sedlacek
Drugs 2000
NF-κB activation in response to toxical and therapeutical agents: role in inflammation and cancer treatment
V Bours, G Bonizzi, M Bentires-Alj, F Bureau, J Piette, P Lekeux, MP Merville
Toxicology 2000
Inhibition of transcription factor nuclear factor-kappaB by a mutant inhibitor-kappaBalpha attenuates resistance of human head and neck squamous cell carcinoma to TNF-alpha caspase-mediated cell death
DC Duffey, CV Crowl-Bancroft, Z Chen, FG Ondrey, M Nejad-Sattari, G Dong, CV Waes
British Journal of Cancer 2000
The molecular and cellular origins of Hodgkin's disease
LM Staudt
Journal of Experimental Medicine 2000
Role of the IkappaB kinase complex in oncogenic Ras- and Raf-mediated transformation of rat liver epithelial cells
M Arsura, F Mercurio, AL Oliver, SS Thorgeirsson, GE Sonenshein
Molecular and cellular biology 2000
Hodgkin's disease and the Epstein-Barr virus
KJ Flavell, PG Murray
Molecular pathology : MP 2000
Regulation of CD30 antigen expression and its potential significance for human disease
ME Kadin
The American Journal of Pathology 2000
Clonal deleterious mutations in the IkappaBalpha gene in the malignant cells in Hodgkin's lymphoma
B Jungnickel, A Staratschek-Jox, A Bräuninger, T Spieker, J Wolf, V Diehl, ML Hansmann, K Rajewsky, R Küppers
Journal of Experimental Medicine 2000
Dietary Anticarcinogens and Antimutagens
S Southon, R Faulks, A Fillery-Travis
Dietary Anticarcinogens and Antimutagens 2000
The Molecular and Cellular Origins of Hodgkin's Disease
LM Staudt
Journal of Experimental Medicine 2000
The transcription factor NF-κB: control of oncogenesis and cancer therapy resistance
MW Mayo, AS Baldwin
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 2000
A high constitutive level of NF-κB is necessary for the viability of mouse adenocarcinoma cells: A possible role of p53
AS Smirnov, AV Budanov, AS Ruzov, AV Ivanov, AV Prokhorchuk, NV Gnuchev, EB Prokhorchuk
Molecular Biology 2000
Constitutive activation of nuclear factor ?B in hepatocellular carcinoma
DI Tai, SL Tsai, YH Chang, SN Huang, TC Chen, KS Chang, YF Liaw
Cancer 2000
Epstein-Barr virus and hodgkin’s disease
LM Weiss
Current Oncology Reports 2000
I?B?-related proteins in normal and transformed colonic epithelial cells
MS Inan, R Place, V Tolmacheva, QS Wang, AK Hubbard, DW Rosenberg, C Giardina
Molecular Carcinogenesis 2000
Distinct Effects of CD30 and Fas Signaling in Cutaneous Anaplastic Lymphomas: A Possible Mechanism for Disease Progression
E Levi, Z Wang, T Petrogiannis-Haliotis, WM Pfeifer, W Kempf, R Drews, ME Kadin
Journal of Investigative Dermatology 2000
Clonal Deleterious Mutations in the I b  Gene in the Malignant Cells in Hodgkin's Lymphoma
B Jungnickel, A Staratschek-Jox, A Brauninger, T Spieker, J Wolf, V Diehl, ML Hansmann, K Rajewsky, R Kuppers
Journal of Experimental Medicine 2000
Apoptosis and radiosensitization of Hodgkin cells by proteasome inhibition
F Pajonk, K Pajonk, WH McBride
International journal of radiation oncology, biology, physics 2000
Selective activation of NF-kappa B subunits in human breast cancer: potential roles for NF-kappa B2/p52 and for Bcl-3
MA Sovak, RE Bellas, DW Kim, GJ Zanieski, AE Rogers, AM Traish, GE Sonenshein
Oncogene 2000
Nuclear factor-kappaB/IkappaB signaling pathway may contribute to the mediation of paclitaxel-induced apoptosis in solid tumor cells
JC Cusack, R Liu, AS Baldwin
Cancer research 2000
Paclitaxel sensitivity of breast cancer cells with constitutively active NF-kappaB is enhanced by IkappaBalpha super-repressor and parthenolide
NM Patel, S Nozaki, NH Shortle, P Bhat-Nakshatri, TR Newton, S Rice, V Gelfanov, SH Boswell, RJ Goulet, GW Sledge, H Nakshatri
Oncogene 2000
Nuclear factor κB in proliferation, activation, and apoptosis in rat hepatic stellate cells
A Lang, R Schoonhoven, S Tuvia, DA Brenner, RA Rippe
Journal of Hepatology 2000
Adenovirus-mediated transfer of caspase-8 in combination with superrepressor of NF-kappaB drastically induced apoptosis in gliomas
N Shinoura, N Yamamoto, Y Yoshida, A Asai, T Kirino, H Hamada
Biochemical and Biophysical Research Communications 2000
Modulation of NF-kappa B activity and apoptosis in chronic lymphocytic leukemia B cells
RR Furman, Z Asgary, JO Mascarenhas, HC Liou, EJ Schattner
Journal of immunology (Baltimore, Md. : 1950) 2000
5-Fluorouracil induces apoptosis through the suppression of NF-kappaB activity in human salivary gland cancer cells
K Aota, M Azuma, T Yamashita, T Tamatani, K Motegi, N Ishimaru, Y Hayashi, M Sato
Biochemical and Biophysical Research Communications 2000
Nuclear factor-kappaB/IkappaB signaling pathway may contribute to the mediation of paclitaxel-induced apoptosis in solid tumor cells
JC Cusack, R Liu, AS Baldwin
Cancer research 2000
Nuclear factor-κB, cancer, and apoptosis
V Bours, M Bentires-Alj, AC Hellin, P Viatour, P Robe, S Delhalle, V Benoit, MP Merville
Biochemical Pharmacology 2000
Phosphatidylcholine-specific phospholipase C and phospholipase D are respectively implicated in mitogen-activated protein kinase and nuclear factor kappaB activation in tumour-necrosis-factor-alpha-treated immature acute-myeloid-leukaemia cells
I Plo, D Lautier, T Levade, H Sekouri, JP Jaffrézou, G Laurent, A Bettaïeb
Biochemical Journal 2000
Hyaluronidase Induction of a WW Domain-containing Oxidoreductase That Enhances Tumor Necrosis Factor Cytotoxicity
NS Chang, N Pratt, J Heath, L Schultz, D Sleve, GB Carey, N Zevotek
The Journal of biological chemistry 2000
Transcription factor NF-κB participates in regulation of epithelial cell turnover in the colon
MS Inan, V Tolmacheva, QS Wang, DW Rosenberg, C Giardina
AJP Gastrointestinal and Liver Physiology 2000
Additive effect between NF-κB subunits and p53 protein for transcriptional activation of human p53 promoter
V Benoit, AC Hellin, S Huygen, J Gielen, V Bours, MP Merville
Oncogene 2000
Enhancement of cytosine arabinoside-induced apoptosis in human myeloblastic leukemia cells by NF-κB/Rel− specific decoy oligodeoxynucleotides
MF Romano, A Lamberti, R Bisogni, P Tassone, D Pagnini, G Storti, LD Vecchio, MC Turco, S Venuta
Gene Therapy 2000
Expression of the Tumor Necrosis Factor Receptor-Associated Factors (TRAFs) 1 and 2 is a Characteristic Feature of Hodgkin and Reed-Sternberg Cells
KF Izban, M Ergin, RL Martinez, S Alkan
Modern Pathology 2000
NF-κB is required for H-ras oncogene induced abnormal cell proliferation and tumorigenesis
H Jo, R Zhang, H Zhang, TA McKinsey, J Shao, RD Beauchamp, DW Ballard, P Liang
Oncogene 2000
Transcription factor NF-κB is constitutively activated in acute lymphoblastic leukemia cells
U Kordes, D Krappmann, V Heissmeyer, WD Ludwig, C Scheidereit
Leukemia 2000
Positive and negative regulation of apoptotic pathways by cytotoxic agents in hematological malignancies
E Solary, N Droin, A Bettaieb, L Corcos, MT Dimanche-Boitrel, C Garrido
Leukemia 2000
Tissue eosinophilia correlates strongly with poor prognosis in nodular sclerosing Hodgkin's disease, allowing for known prognostic factors
R von Wasielewski, S Seth, J Franklin, R Fischer, K Hübner, ML Hansmann, V Diehl, A Georgii
Blood 2000
The Rel/NF-κB Family Directly Activates Expression of the Apoptosis Inhibitor Bcl-x L
C Chen, LC Edelstein, C Gélinas
Molecular and cellular biology 2000
IFN-α Suppresses Activation of Nuclear Transcription Factors NF-κB and Activator Protein 1 and Potentiates TNF-Induced Apoptosis
SK Manna, A Mukhopadhyay, BB Aggarwal
Journal of immunology (Baltimore, Md. : 1950) 2000
Differential effects of CD30 activation in anaplastic large cell lymphoma and Hodgkin disease cells
SS Mir, BW Richter, CS Duckett
Blood 2000
Isolation and characterization of an acute promyelocytic leukemia cell line selectively resistant to the novel antileukemic and apoptogenic retinoid 6-[3-adamantyl-4-hydroxyphenyl]-2-naphthalene carboxylic acid
I Ponzanelli, M Giannı̀, R Giavazzi, A Garofalo, I Nicoletti, U Reichert, E Erba, A Rambaldi, M Terao, E Garattini
Blood 2000
Kinase Inhibitors in Cancer Therapy: A Look Ahead
H Sedlacek
Drugs 2000
Epstein-Barr virus and Hodgkin's disease.
Weiss LM
Current Oncology Reports 2000
NF-κB Controls Cell Growth and Differentiation through Transcriptional Regulation of Cyclin D1
DC Guttridge, C Albanese, JY Reuther, RG Pestell, AS Baldwin
Molecular and cellular biology 1999
Recent advances in the molecular pathogenesis of lymphomas
A Sarris, R Ford
Current Opinion in Oncology 1999
Genistein Inhibits Constitutive and Inducible NFκB Activation and Decreases IL-8 Production by Human Cystic Fibrosis Bronchial Gland Cells
O Tabary, S Escotte, JP Couetil, D Hubert, D Dusser, E Puchelle, J Jacquot
The American Journal of Pathology 1999
Genistein inhibits constitutive and inducible NFkappaB activation and decreases IL-8 production by human cystic fibrosis bronchial gland cells
O Tabary, S Escotte, JP Couetil, D Hubert, D Dusser, E Puchelle, J Jacquot
The American Journal of Pathology 1999
NF-κB involvement in the activation of primary adult T-cell leukemia cells and its clinical implications
N Arima, K Matsushita, H Obata, H Ohtsubo, H Fujiwara, K Arimura, T Kukita, Y Suruga, S Wakamatsu, S Hidaka, C Tei
Experimental Hematology 1999
Apoptosis and HIV infection: T-cells fiddle while the immune system burns
B Goldberg, RB Stricker
Immunology Letters 1999
Iκβα Is Essential for Maintaining Basal c-Jun N-Terminal Kinase (JNK) Activation and Regulating JNK-Mediated Resistance to Tumor Necrosis Factor Cytotoxicity in L929 Cells
NS Chang
Biochemical and Biophysical Research Communications 1999
NF- κ B and chemoresistance: could NF- κ B be an antitumor target?
M Bentires-Alj, MP Merville, V Bours
Drug Resistance Updates 1999
New insights into the roles of ReL/NF-κB transcription factors in immune function, hemopoiesis and human disease
M Grossmann, Y Nakamura, R Grumont, S Gerondakis
The International Journal of Biochemistry & Cell Biology 1999
The NF-κB/Rel family of transcription factors in oncogenic transformation and apoptosis
R Martin, JA Schmid, R Hofer-Warbinek
Mutation Research/Reviews in Mutation Research 1999
9-Nitrocamptothecin Selectively Inhibits Human Immunodeficiency Virus Type 1 Replication in Freshly Infected Parental but Not 9-Nitrocamptothecin-Resistant U937 Monocytoid Cells
MR Sadaie, J Doniger, CL Hung, P Pantazis
AIDS Research and Human Retroviruses 1999
Transcription Factors in Lymphocyte Development— T and B Cells Get Together
LH Glimcher, H Singh
Cell 1999
Paediatric Hodgkin's disease
R Pötter
European Journal of Cancer 1999
Aberrant rel/nfkb genes and activity in human cancer
B Rayet, C Gélinas
Oncogene 1999
Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IkappaBalpha
H Ishikawa, D Carrasco, E Claudio, RP Ryseck, R Bravo
Oncogene 1999
Mutations in the IkBa gene in Hodgkin's disease suggest a tumour suppressor role for IkappaBalpha
H Ishikawa, D Carrasco, E Claudio, RP Ryseck, R Bravo
Oncogene 1999
NSAIDs and butyrate sensitize a human colorectal cancer cell line to TNF-alpha and Fas ligation: the role of reactive oxygen species
C Giardina, H Boulares, M S Inan
Biochimica et Biophysica Acta 1999
How NF-κB is activated: the role of the IκB kinase (IKK) complex
M Karin
Oncogene 1999
The Beginning of the End: IκB Kinase (IKK) and NF-κB Activation
M Karin
The Journal of biological chemistry 1999
Persistent activation of nuclear factor-?B in cultured rat hepatic stellate cells involves the induction of potentially novel rel-like factors and prolonged changes in the expression of I?B family proteins
AM Elsharkawy, MC Wright, RT Hay, MJ Arthur, T Hughes, MJ Bahr, K Degitz, DA Mann
Hepatology 1999
Molecular mechanisms of constitutive NF-κB/Rel activation in Hodgkin/Reed-Sternberg cells
D Krappmann, F Emmerich, U Kordes, E Scharschmidt, B Dörken, C Scheidereit
Oncogene 1999
Repression of NF-κB impairs HeLa cell proliferation by functional interference with cell cycle checkpoint regulators
B Kaltschmidt, C Kaltschmidt, SP Hehner, W Dröge, ML Schmitz
Oncogene 1999
Negative Regulation of Transactivation Function but Not DNA Binding of NF-κB and AP-1 by IκBβ1 in Breast Cancer Cells
TR Newton, NM Patel, P Bhat-Nakshatri, CR Stauss, RJ Goulet, H Nakshatri
The Journal of biological chemistry 1999
Constitutive activation of transcription factors NF-?B, AP-1, and NF-IL6 in human head and neck squamous cell carcinoma cell lines that express pro-inflammatory and pro-angiogenic cytokines
FG Ondrey, G Dong, J Sunwoo, Z Chen, JS Wolf, CV Crowl-Bancroft, N Mukaida, CV Waes
Molecular Carcinogenesis 1999
Regulation of NF-κB activity by IκB-related proteins in adenocarcinoma cells
E Dejardin, V Deregowski, M Chapelier, N Jacobs, J Gielen, MP Merville, V Bours
Oncogene 1999
NF-κB as a primary regulator of the stress response
F Mercurio, AM Manning
Oncogene 1999
Apoptosis overrides survival signals through a caspase-mediated dominant-negative NF-κB loop
B Levkau, M Scatena, CM Giachelli, R Ross, EW Raines
Nature Cell Biology 1999
Integration of Rac-dependent Regulation of Cyclin D1 Transcription through a Nuclear Factor-κB-dependent Pathway
D Joyce, B Bouzahzah, M Fu, C Albanese, M DAmico, J Steer, JU Klein, RJ Lee, JE Segall, JK Westwick, CJ Der, RG Pestell
The Journal of biological chemistry 1999
Latent membrane protein 1 associated signaling pathways are important in tumor cells of Epstein-Barr virus negative Hodgkin's disease
H Knecht, C Berger, C McQuain, S Rothenberger, E Bachmann, J Martin, C Esslinger, HG Drexler, YC Cai, PJ Quesenberry, BF Odermatt
Oncogene 1999
NF-κB Function in Growth Control: Regulation of Cyclin D1 Expression and G 0 /G 1 -to-S-Phase Transition
M Hinz, D Krappmann, A Eichten, A Heder, C Scheidereit, M Strauss
Molecular and cellular biology 1999
Role of NF-κB in the Rescue of Multiple Myeloma Cells From Glucocorticoid-Induced Apoptosis by Bcl-2
R Feinman, J Koury, M Thames, B Barlogie, J Epstein, DS Siegel
Blood 1999
NF-κB Controls Cell Growth and Differentiation through Transcriptional Regulation of Cyclin D1
DC Guttridge, C Albanese, JY Reuther, RG Pestell, AS Baldwin
Molecular and cellular biology 1999
Tumor Necrosis Factor Receptor-Associated Factor 1 Is Overexpressed in Reed-Sternberg Cells of Hodgkin’s Disease and Epstein-Barr Virus-Transformed Lymphoid Cells
H Dürkop, HD Foss, G Demel, H Klotzbach, C Hahn, H Stein
Blood 1999
CD30-CD30 Ligand Interaction in Primary Cutaneous CD30+T-Cell Lymphomas: A Clue to the Pathophysiology of Clinical Regression
M Mori, C Manuelli, N Pimpinelli, C Mavilia, E Maggi, M Santucci, B Bianchi, P Cappugi, B Giannotti, ME Kadin
Blood 1999
Overexpression of I Kappa B Alpha Without Inhibition of NF-κB Activity and Mutations in the I Kappa B Alpha Gene in Reed-Sternberg Cells
F Emmerich, M Meiser, M Hummel, G Demel, HD Foss, F Jundt, S Mathas, D Krappmann, C Scheidereit, H Stein, B Dörken
Blood 1999
Mutation of the p53 Gene Is Not a Typical Feature of Hodgkin and Reed-Sternberg Cells in Hodgkin’s Disease
M Montesinos-Rongen, A Roers, R Küppers, K Rajewsky, ML Hansmann
Blood 1999
Transcriptional Cross Talk between NF-κB and p53
GA Webster, ND Perkins
Molecular and cellular biology 1999
Transcriptional Cross Talk between NF-κB and p53
GA Webster, ND Perkins
Molecular and cellular biology 1999
Transcriptional cross talk between NF-kappaB and p53.
Webster GA, Perkins ND
Molecular and cellular biology 1999
Activation of NF-kappaB by adherent Pseudomonas aeruginosa in normal and cystic fibrosis respiratory epithelial cells
E DiMango, AJ Ratner, R Bryan, S Tabibi, A Prince
Journal of Clinical Investigation 1998
A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation
JY Reuther, GW Reuther, D Cortez, AM Pendergast, AS Baldwin
Genes & development 1998
Isolation of viable Hodgkin and Reed-Sternberg cells from Hodgkin disease tissues
J Irsch, S Nitsch, ML Hansmann, K Rajewsky, H Tesch, V Diehl, A Jox, R Küppers, A Radbruch
Proceedings of the National Academy of Sciences 1998
Chronic Antagonism of Nuclear Factor-κB Activity in Cytotrophoblasts by Dexamethasone: A Potential Mechanism for Antiinflammatory Action of Glucocorticoids in Human Placenta1
T Rosen, G Krikun, Y Ma, EY Wang, CJ Lockwood, S Guller
The Journal of clinical endocrinology and metabolism 1998
Clinically relevant findings
TD Gilmore
Journal of Clinical Investigation 1997

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