Research Article
G A Soff, T L Cornwell, D L Cundiff, S Gately, T M Lincoln
Title and authors | Publication | Year |
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Antihypertensive and Vasorelaxant Effects of Citric Acid and Lemon Juice in Spontaneously Hypertensive Rats: In Vivo and Ex Vivo Studies.
Nakamura K, Suzuki Y, Goto K, Yamaguchi S, Hiramitsu M |
Nutrients | 2023 |
Unique Aspects of the Developing Lung Circulation: Structural Development and Regulation of Vasomotor Tone
Y Gao, DN Cornfield, KR Stenmark, B Thébaud, SH Abman, JU Raj |
Pulmonary circulation | 2016 |
cGMP and epigenetic factor in the suppression of apoptosis in ovarian follicles
VP Chakravarthi, Y Sireesha, YN Kumar, AV kumar, M Bhaskar |
Russian Journal of Developmental Biology | 2016 |
Study of the cellular mechanism of Sunitinib mediated inactivation of activated hepatic stellate cells and its implications in angiogenesis
S Majumder, AC Piguet, JF Dufour, S Chatterjee |
European Journal of Pharmacology | 2013 |
Protein Kinase G1 α Overexpression Increases Stem Cell Survival and Cardiac Function after Myocardial Infarction
L Wang, Z Pasha, S Wang, N Li, Y Feng, G Lu, RW Millard, M Ashraf, P Anversa |
PloS one | 2013 |
Protein Kinase G-I Deficiency Induces Pulmonary Hypertension through Rho A/Rho Kinase Activation
YD Zhao, L Cai, MK Mirza, X Huang, DL Geenen, F Hofmann, JX Yuan, YY Zhao |
The American Journal of Pathology | 2012 |
Transcriptional and post-transcriptional regulation of cGMP-dependent protein kinase (PKG-I): pathophysiological significance
H Sellak, C Choi, NB Dey, TM Lincoln |
Cardiovascular Research | 2012 |
Stabilization of cGMP-dependent protein kinase G (PKG) expression in vascular smooth muscle cells: contribution of 3′UTR of its mRNA
H Sellak, TM Lincoln, CS Choi |
Journal of Biochemistry | 2011 |
Suppression of PKG by PDGF or nitric oxide in differentiated aortic smooth muscle cells: obligatory role of protein tyrosine phosphatase 1B
D Zhuang, P Balani, Q Pu, S Thakran, A Hassid |
American journal of physiology. Heart and circulatory physiology | 2011 |
Fibronectin upregulates cGMP-dependent protein kinase type Iβ through C/EBP transcription factor activation in contractile cells
A Chamorro-Jorganes, L Calleros, M Griera, M Saura, A Luengo, D Rodriguez-Puyol, M Rodriguez-Puyol |
American journal of physiology. Cell physiology | 2011 |
cGMP-dependent protein kinases as potential targets for colon cancer prevention and treatment
DD Browning, IK Kwon, R Wang |
Future Medicinal Chemistry | 2010 |
Increased degradation of MYPT1 contributes to the development of tolerance to nitric oxide in porcine pulmonary artery
H Ma, Q He, D Dou, X Zheng, L Ying, Y Wu, JU Raj, Y Gao |
American journal of physiology. Lung cellular and molecular physiology | 2010 |
Testosterone-Induced Modulation of Nitric Oxide-cGMP Signaling Pathway and Androgenesis in the Rat Leydig Cells1
SA Andric, MM Janjic, NJ Stojkov, TS Kostic |
Biology of reproduction | 2010 |
Predisposition to atherosclerosis and aortic aneurysms in mice deficient in kinin B1 receptor and apolipoprotein E
VF Merino, M Todiras, MA Mori, VM Sales, RG Fonseca, V Saul, K Tenner, M Bader, JB Pesquero |
Journal of Molecular Medicine | 2009 |
ROLE OF CYCLIC NUCLEOTIDES IN THE CONTROL OF CYTOSOLIC Ca2+LEVELS IN VASCULAR ENDOTHELIAL CELLS
HY Kwan, Y Huang, XQ Yao, FP Leung |
Clinical and Experimental Pharmacology and Physiology | 2009 |
Prolonged treatment of porcine pulmonary artery with nitric oxide decreases cGMP sensitivity and cGMP-dependent protein kinase specific activity
WJ Perkins, DO Warner, KA Jones |
American journal of physiology. Lung cellular and molecular physiology | 2009 |
Cyclic GMP specifically suppresses Type-Iα cGMP-dependent protein kinase expression by ubiquitination
NB Dey, JL Busch, SH Francis, JD Corbin, TM Lincoln |
Cellular Signalling | 2009 |
Role of cGMP-dependent protein kinase in development of tolerance to nitroglycerine in porcine coronary arteries
D Dou, X Zheng, X Qin, H Qi, L Liu, JU Raj, Y Gao |
British Journal of Pharmacology | 2008 |
Glucose down-regulation of cGMP-dependent protein kinase I expression in vascular smooth muscle cells involves NAD(P)H oxidase-derived reactive oxygen species
S Liu, X Ma, M Gong, L Shi, T Lincoln, S Wang |
Free radical biology & medicine | 2007 |
Activated pericyte attenuates endothelial functions: nitric oxide – cGMP rescues activated pericyte-associated endothelial dysfunctions
S Majumder, KP Tamilarasan, GK Kolluru, A Muley, CM Nair, A Omanakuttan, KV Murty, S Chatterjee |
Biochemistry and Cell Biology | 2007 |
V.A.C. Therapy Normalizes Vascular Response of Injured Tissue in Full-Thickness Wounds in Rabbits
DV Kilpadi, TD Feeley, JW Kiel |
Annals of Plastic Surgery | 2007 |
Reduction in soluble guanylyl cyclase-specific activity following prolonged treatment of porcine pulmonary artery with nitric oxide
WJ Perkins, M Taniguchi, DO Warner, EN Chini, KA Jones |
American journal of physiology. Lung cellular and molecular physiology | 2007 |
cGMP signals mainly through cAMP kinase in permeabilized murine aorta
R Wörner, R Lukowski, F Hofmann, JW Wegener |
American journal of physiology. Heart and circulatory physiology | 2007 |
Cyclic GMP-dependent protein kinase and soluble guanylyl cyclase disappear in elicited rat neutrophils
M Ciuman, J Siednienko, R Czyżyk, H Witwicka, E Kołosionek, M Kobiałka, WA Gorczyca |
Biochimica et Biophysica Acta (BBA) - General Subjects | 2006 |
An anti-tumor role for cGMP-dependent protein kinase
Y Hou, N Gupta, P Schoenlein, E Wong, R Martindale, V Ganapathy, D Browning |
Cancer Letters | 2006 |
Nitric oxide induces phosphodiesterase 4B expression in rat pulmonary artery smooth muscle cells
CJ Busch, H Liu, AR Graveline, KD Bloch |
American journal of physiology. Lung cellular and molecular physiology | 2006 |
Nitric oxide sensitivity in pulmonary artery and airway smooth muscle: a possible role for cGMP responsiveness
M Taniguchi, YL Kwak, KA Jones, DO Warner, WJ Perkins |
American journal of physiology. Lung cellular and molecular physiology | 2006 |
Regulation of cGMP-dependent Protein Kinase Expression by Rho and Krüppel-like Transcription Factor-4
Y Zeng, S Zhuang, J Gloddek, CC Tseng, GR Boss, RB Pilz |
The Journal of biological chemistry | 2006 |
Chronic intrauterine pulmonary hypertension selectively modifies pulmonary artery smooth muscle cell gene expression
E Resnik, J Herron, M Keck, D Sukovich, B Linden, DN Cornfield |
American journal of physiology. Lung cellular and molecular physiology | 2006 |
Nitric oxide and cGMP protein kinase (cGK) regulate dendritic-cell migration toward the lymph-node–directing chemokine CCL19
D Giordano, DM Magaletti, EA Clark |
Blood | 2006 |
Induction of tissue kallikrein in human carotid atheroma does not lead to kallikrein-kinins pathway activation
L Legedz, J Randon, C Sessa, JP Baguet, P Feugier, C Cerutti, MC Bourdillon, G Bricca |
Journal of Hypertension | 2005 |
Characteristics of attenuated endothelium-dependent relaxation seen in rabbit intrapulmonary vein following chronic nitroglycerine administration
N Kusama, J Kajikuri, Y Watanabe, Y Suzuki, H Katsuya, T Itoh |
British Journal of Pharmacology | 2005 |
Chronic nitroglycerine administration reduces endothelial nitric oxide production in rabbit mesenteric resistance artery
T Yamamoto, J Kajikuri, Y Watanabe, Y Suzuki, K Suzumori, T Itoh |
British Journal of Pharmacology | 2005 |
Nitroglycerin-patch induced tolerance is associated with reduced ability of nitroglycerin to increase exhaled nitric oxide
P Agvald, L Hammar, LE Gustafsson |
Vascular Pharmacology | 2005 |
Upstream Stimulatory Factors (USF-1/USF-2) Regulate Human cGMP-dependent Protein Kinase I Gene Expression in Vascular Smooth Muscle Cells
H Sellak, CS Choi, N Browner, TM Lincoln |
The Journal of biological chemistry | 2005 |
Cell Signaling in Vascular Inflammation
J Bhattacharya |
2005 | |
Role of PKC in the attenuation of the cGMP-mediated relaxation of skinned resistance artery smooth muscle seen in glyceryl-trinitrate-tolerant rabbit
Y Nakano, N Kusama, J Kajikuri, Y Suzuki, Y Kanmura, T Itoh |
British Journal of Pharmacology | 2004 |
Intravenous Nitroglycerin in the Treatment of Decompensated Heart Failure: Potential Benefits and Limitations
U Elkayam, F Bitar, MW Akhter, S Khan, S Patrus, M Derakhshani |
Journal of cardiovascular pharmacology and therapeutics | 2004 |
Downregulation of cGMP-dependent protein kinase expression by inflammatory cytokines in vascular smooth muscle cells
NC Browner, H Sellak, TM Lincoln |
American journal of physiology. Cell physiology | 2004 |
Role of cGMP-dependent protein kinase in development of tolerance to nitric oxide in pulmonary veins of newborn lambs
Y Gao, S Dhanakoti, EM Trevino, X Wang, FC Sander, AD Portugal, JU Raj |
American journal of physiology. Lung cellular and molecular physiology | 2004 |
Regulation of rat pial arteriolar smooth muscle relaxation in vivo through multidrug resistance protein 5-mediated cGMP efflux
HL Xu, V Gavrilyuk, HM Wolde, VL Baughman, DA Pelligrino |
American journal of physiology. Heart and circulatory physiology | 2004 |
The Role of Nitric Oxide in Heart Failure
BI Jugdutt |
2004 | |
Nitric Oxide Regulates c- fos Expression in Nucleus Tractus Solitarii Induced by Baroreceptor Activation via cGMP-Dependent Protein Kinase and cAMP Response Element-Binding Protein Phosphorylation
SH Chan, KF Chang, CC Ou, JY Chan |
Molecular pharmacology | 2004 |
Interactions of Homocysteine, Nitric Oxide, Folate and Radicals in the Progressively Damaged Endothelium
O Stanger, M Weger |
Clinical Chemistry and Laboratory Medicine | 2003 |
Up and Down-Regulation of Phosphodiesterase-5 as Related to Tachyphylaxis and Priapism
G Lin, ZC Xin, TF Lue, CS Lin |
The Journal of Urology | 2003 |
Inhibition of cyclic guanosine 5′-monophosphate-dependent protein kinase I (PKG-I) in lumbar spinal cord reduces formalin-induced hyperalgesia and PKG upregulation
A Schmidtko, P Ruth, G Geisslinger, I Tegeder |
Nitric Oxide | 2003 |
Selective phosphorylation of the IP 3 R-I in vivo by cGMP-dependent protein kinase in smooth muscle
KS Murthy, H Zhou |
AJP Gastrointestinal and Liver Physiology | 2003 |
Prolonged exposure of chromaffin cells to nitric oxide down-regulates the activity of soluble guanylyl cyclase and corresponding mRNA and protein levels
R Ferrero, M Torres |
BMC Biochemistry | 2002 |
Regulation of cardiac remodeling by nitric oxide: focus on cardiac myocyte hypertrophy and apoptosis
Kai C Wollert, Helmut Drexler |
Heart Failure Reviews | 2002 |
Cyclic GMP-dependent vasodilatory properties of LASSBio 294 in rat aorta
CL Silva, F Noël, EJ Barreiro |
British Journal of Pharmacology | 2002 |
Cyclic AMP and cyclic GMP activate protein kinase G in cavernosal smooth muscle cells: old age is a negative factor
CS Lin, X Liu, S Chow, TF Lue |
BJU International | 2002 |
Dual effects of spinally delivered 8-bromo-cyclic guanosine mono-phosphate (8-bromo-cGMP) in formalin-induced nociception in rats
I Tegeder |
Neuroscience Letters | 2002 |
Antipyretic role of the NO-cGMP pathway in the anteroventral preoptic region of the rat brain
AA Steiner, J Antunes-Rodrigues, SM McCann, LG Branco |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2002 |
Sp1 Transcription Factor as a Molecular Target for Nitric Oxide– and Cyclic Nucleotide–Mediated Suppression of cGMP-Dependent Protein Kinase-Iα Expression in Vascular Smooth Muscle Cells
H Sellak, X Yang, X Cao, T Cornwell, GA Soff, T Lincoln |
Circulation research | 2002 |
Nitrate Tolerance: A Unifying Hypothesis
T Gori, JD Parker |
Circulation | 2002 |
Gene Transfer of cGMP-Dependent Protein Kinase I Enhances the Antihypertrophic Effects of Nitric Oxide in Cardiomyocytes
KC Wollert, B Fiedler, S Gambaryan, A Smolenski, J Heineke, E Butt, C Trautwein, SM Lohmann, H Drexler |
Hypertension | 2002 |
Regulation of Cyclooxygenase-2 Expression by Nitric Oxide in Cells
D Pérez-Sala, S Lamas |
Antioxidants & Redox Signaling | 2001 |
Age-Related Decrease of Protein Kinase G Activation in Vascular Smooth Muscle Cells
CS Lin, X Liu, R Tu, S Chow, TF Lue |
Biochemical and Biophysical Research Communications | 2001 |
Heart Physiology and Pathophysiology
NS Dhalla, RM Temsah, T Netticadan, MS Sandhu |
Heart Physiology and Pathophysiology | 2001 |
Effects of in vivo nitroglycerin treatment on activity and expression of the guanylyl cyclase and cGMP-dependent protein kinase and their downstream target vasodilator-stimulated phosphoprotein in aorta
A Mülsch, M Oelze, S Klöss, H Mollnau, A Töpfer, A Smolenski, U Walter, JP Stasch, A Warnholtz, U Hink, T Meinertz, T Münzel |
Circulation | 2001 |
Requirement of protein tyrosine phosphatase SHP2 for NO-stimulated vascular smooth muscle cell motility
C Brown, Y Lin, A Hassid |
American journal of physiology. Heart and circulatory physiology | 2001 |
Endothelial cell protein kinase G inhibits release of EDHF through a PKG-sensitive cation channel
KA Dora, CJ Garland, HY Kwan, X Yao |
American journal of physiology. Heart and circulatory physiology | 2001 |
Posttranscriptional regulation of human iNOS by the NO/cGMP pathway
D Pérez-Sala, E Cernuda-Morollón, M Díaz-Cazorla, F Rodríguez-Pascual, S Lamas |
American journal of physiology. Renal physiology | 2001 |
Nitric Oxide Signaling Pathway Regulates Potassium Chloride Cotransporter-1 mRNA Expression in Vascular Smooth Muscle Cells
MD Fulvio, PK Lauf, NC Adragna |
The Journal of biological chemistry | 2001 |
Protein Kinase G Regulates Potassium Chloride Cotransporter-3 Expression in Primary Cultures of Rat Vascular Smooth Muscle Cells
MD Fulvio, TM Lincoln, PK Lauf, NC Adragna |
The Journal of biological chemistry | 2001 |
A cGMP-Dependent Protein Kinase Assay for High Throughput Screening Based on Time-Resolved Fluorescence Resonance Energy Transfer
B Bader, E Butt, A Palmetshofer, U Walter, T Jarchau, P Drueckesl |
Journal of biomolecular screening | 2001 |
Reciprocal regulation of cGMP-mediated vasorelaxation by soluble and particulate guanylate cyclases
MB Hussain, RJ MacAllister, AJ Hobbs |
American journal of physiology. Heart and circulatory physiology | 2001 |
Invited Review: cGMP-dependent protein kinase signaling mechanisms in smooth muscle: from the regulation of tone to gene expression
TM Lincoln, N Dey, H Sellak |
Journal of applied physiology | 2001 |
Suppression of Proliferation of Human Coronary Artery Smooth Muscle Cells by the Nitric Oxide Donor, S-Nitrosoglutathione, Is cGMP-Independent
DV Young, D Serebryanik, DR Janero, SW Tam |
Molecular Cell Biology Research Communications | 2000 |
Mechanisms of NO/cGMP-dependent vasorelaxation
M Sausbier, R Schubert, V Voigt, C Hirneiss, A Pfeifer, M Korth, T Kleppisch, P Ruth, F Hofmann |
Circulation research | 2000 |
Role of Nitric Oxide in the Pathogenesis of Chronic Pulmonary Hypertension
V Hampl, J Herget |
Physiological reviews | 2000 |
Cyclic GMP–Dependent Protein Kinase Expression in Coronary Arterial Smooth Muscle in Response to Balloon Catheter Injury
PG Anderson, NJ Boerth, M Liu, DB McNamara, TL Cornwell, TM Lincoln |
Arteriosclerosis, thrombosis, and vascular biology | 2000 |
Mechanisms of Reduced Nitric Oxide/cGMP–Mediated Vasorelaxation in Transgenic Mice Overexpressing Endothelial Nitric Oxide Synthase
T Yamashita, S Kawashima, Y Ohashi, M Ozaki, Y Rikitake, N Inoue, K Hirata, H Akita, M Yokoyama |
Hypertension | 2000 |
Autoregulation of nitric oxide-soluble guanylate cyclase-cyclic GMP signalling in mouse thoracic aorta
MB Hussain, AJ Hobbs, RJ MacAllister |
British Journal of Pharmacology | 1999 |
Genomic origin and transcriptional regulation of two variants of cGMP-binding cGMP-specific phosphodiesterases
J Kotera, K Fujishige, Y Imai, E Kawai, H Michibata, H Akatsuka, N Yanaka, K Omori |
European Journal of Biochemistry | 1999 |
NO induces a cGMP-independent release of cytochrome c from mitochondria which precedes caspase 3 activation in insulin producing RINm5F cells
J Tejedo, JC Bernabé, R Ramı́rez, F Sobrino, FJ Bedoya |
FEBS Letters | 1999 |
Downregulation of soluble guanylyl cyclase in young and aging spontaneously hypertensive rats
H Ruetten, U Zabel, W Linz, HH Schmidt |
Circulation research | 1999 |
Nitric Oxide Regulation of Gene Transcription via Soluble Guanylate Cyclase and Type I cGMP-dependent Protein Kinase
SD Idriss, T Gudi, DE Casteel, VG Kharitonov, RB Pilz, GR Boss |
The Journal of biological chemistry | 1999 |
Vascular Biology in Genetically Altered Mice: Smaller Vessels, Bigger Insight
FM Faraci, CD Sigmund |
Circulation research | 1999 |
Dual Effect of Nitric Oxide Donors on Cyclooxygenase-2 Expression in Human Mesangial Cells
M Díaz-Cazorla, D Pérez-Sala, S Lamas |
Journal of the American Society of Nephrology : JASN | 1999 |
Endogenous or overexpressed cGMP-dependent protein kinases inhibit cAMP-dependent renin release from rat isolated perfused kidney, microdissected glomeruli, and isolated juxtaglomerular cells
S Gambaryan, C Wagner, A Smolenski, U Walter, W Poller, W Haase, A Kurtz, SM Lohmann |
Proceedings of the National Academy of Sciences | 1998 |
Advances in Organ Biology
AJ Liedtke |
Advances in Organ Biology | 1998 |
Natriuretic factors and nitric oxide suppress plasminogen activator inhibitor-1 expression in vascular smooth muscle cells. Role of cGMP in the regulation of the plasminogen system
JL Bouchie, H Hansen, EP Feener |
Arteriosclerosis, thrombosis, and vascular biology | 1998 |
Adenovirus-mediated gene transfer of cGMP-dependent protein kinase increases the sensitivity of cultured vascular smooth muscle cells to the antiproliferative and pro-apoptotic effects of nitric oxide/cGMP
JD Chiche, SM Schlutsmeyer, DB Bloch, SM de la Monte, JD Roberts, G Filippov, SP Janssens, A Rosenzweig, KD Bloch |
The Journal of biological chemistry | 1998 |
Nitric oxide - cyclic GMP pathway regulates vascular smooth muscle cell phenotypic modulation: implications in vascular diseases
T Lincoln, N Dey, N Boerth, T Cornwell, G Soff |
Acta Physiologica Scandinavica | 1998 |
Nitric Oxide
RA Schroeder, PC Kuo |
Anesthesia & Analgesia | 1995 |