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Citations to this article

Allergen-induced increases in IL-5 receptor alpha-subunit expression on bone marrow-derived CD34+ cells from asthmatic subjects. A novel marker of progenitor cell commitment towards eosinophilic differentiation.
R Sehmi, … , P M O'Byrne, J A Denburg
R Sehmi, … , P M O'Byrne, J A Denburg
Published November 15, 1997
Citation Information: J Clin Invest. 1997;100(10):2466-2475. https://doi.org/10.1172/JCI119789.
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Allergen-induced increases in IL-5 receptor alpha-subunit expression on bone marrow-derived CD34+ cells from asthmatic subjects. A novel marker of progenitor cell commitment towards eosinophilic differentiation.

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Abstract

Research Article

Authors

R Sehmi, L J Wood, R Watson, R Foley, Q Hamid, P M O'Byrne, J A Denburg

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The effect of cysteinyl leukotrienes on growth of eosinophil progenitors from peripheral blood and bone marrow of atopic subjects
F Braccioni, SC Dorman, PM O'Byrne, MD Inman, JA Denburg, K Parameswaran, AJ Baatjes, R Foley, GM Gauvreau
Journal of Allergy and Clinical Immunology 2002
Allergen-induced increases in bone marrow T lymphocytes and interleukin-5 expression in subjects with asthma
LJ Wood, R Sehmi, S Dorman, Q Hamid, MK Tulic, RM Watson, R Foley, P Wasi, JA Denburg, G Gauvreau, PM O'Byrne
American journal of respiratory and critical care medicine 2002
Retinoic acid modulates IL-5 receptor expression and selectively inhibits eosinophil-basophil differentiation of hemopoietic progenitor cells
JW Upham, R Sehmi, LM Hayes, K Howie, J Lundahl, JA Denburg
Journal of Allergy and Clinical Immunology 2002
Intranasal fluticasone propionate inhibits allergen induced bone marrow eosinophilia in mice
S Sergejeva, M Tomaki, T Pullerits, LL Zhao, M Johnson, J Lötvall
Pulmonary Pharmacology & Therapeutics 2002
IgE and Anti-IgE Therapy in Asthma and Allergic Disease: Pathogenesis and Novel Therapeutic Strategies
J Lordan, S Holgate, I Sayers
IgE and Anti-IgE Therapy in Asthma and Allergic Disease: Pathogenesis and Novel Therapeutic Strategies 2002
Pathogenesis of murine experimental allergic rhinitis: a study of local and systemic consequences of IL-5 deficiency
H Saito, K Matsumoto, AE Denburg, L Crawford, R Ellis, MD Inman, R Sehmi, K Takatsu, KI Matthaei, JA Denburg
Journal of immunology (Baltimore, Md. : 1950) 2002
Human Cell Culture
MR Koller, BO Palsson, JR Masters
2002
Interleukin-5 induces CD34(+) eosinophil progenitor mobilization and eosinophil CCR3 expression in asthma
RG Stirling, EL van Rensen, PJ Barnes, KF Chung
American journal of respiratory and critical care medicine 2001
Interleukin-5 in growth and differentiation of blood eosinophil progenitors in asthma: effect of glucocorticoids
HP Kuo, CH Wang, HC Lin, KS Hwang, SL Liu, KF Chung
British Journal of Pharmacology 2001
Advances in the pathophysiology of bronchial asthma
S Muro, QA Hamid
Allergology International 2001
Atopic NC/Nga Mice as a Model for Allergic Asthma: Severe Allergic Responses by Single Intranasal Challenge with Protein Antigen
T IWASAKI, A TANAKA, A ITAKURA, N YAMASHITA, K OHTA, H MATSUDA, M ONUMA
Journal of Veterinary Medical Science 2001
Systemic aspects of allergic disease: the role of the bone marrow
MM Cyr, JA Denburg
Current Opinion in Immunology 2001
The nose-lung interaction in allergic rhinitis and asthma: united airways disease
G Passalacqua, G Ciprandi, GW Canonica
Current Opinion in Allergy and Clinical Immunology 2001
Human mast cell progenitors in peripheral blood from atopic subjects with high IgE levels
I Nomura, T Katsunuma, K Matsumoto, M Iida, H Tomita, M Tomikawa, H Kawahara, A Akasawa, R Pawankar, H Saito
Clinical & Experimental Allergy 2001
Role of IL-9 in the pathophysiology of allergic diseases
A Soussi-Gounni, M Kontolemos, Q Hamid
Journal of Allergy and Clinical Immunology 2001
The trials and tribulations of IL-5, eosinophils, and allergic asthma
PM O'Byrne, MD Inman, K Parameswaran
Journal of Allergy and Clinical Immunology 2001
Lung Biology in Health and Disease: Pathogenesis and Clinical Management
R Ballard
Lung Biology in Health and Disease: Experimental Models and Therapeutic Potential 2001
In Vitro and In Vivo Inhibition of Interleukin (IL)-5–Mediated Eosinopoiesis by Murine IL-5R α Antisense Oligonucleotide
E Lach-Trifilieff, RA McKay, BP Monia, JG Karras, C Walker
American journal of respiratory cell and molecular biology 2001
An Increase in Circulating Mast Cell Colony-Forming Cells in Asthma
HH Mwamtemi, K Koike, T Kinoshita, S Ito, S Ishida, Y Nakazawa, Y Kurokawa, K Shinozaki, K Sakashita, K Takeuchi, M Shiohara, T Kamijo, Y Yasui, A Ishiguro, Y Kawano, K Kitano, H Miyazaki, T Kato, S Sakuma, A Komiyama
Journal of immunology (Baltimore, Md. : 1950) 2001
Mechanisms of eosinophil-associated inflammation
GJ Gleich
Journal of Allergy and Clinical Immunology 2000
IL-5: biology and potential therapeutic applications
JK Weltman, AS Karim
Expert Opinion on Investigational Drugs 2000
Molecular pathology of allergic disease I: Lower airway disease
QA Hamid, EM Minshall
Journal of Allergy and Clinical Immunology 2000
Murine myeloid progenitor responses to GM-CSF and eosinophil precursor responses to IL-5 represent distinct targets for downmodulation by prostaglandin E(2)
MI Elsas, D Joseph, L Lintomen, ES Maximiano, M Bodstein, PX Elsas, BB Vargaftig
British Journal of Pharmacology 2000
Haemopoietic mechanisms in nasal polyposis and asthma
JA Denburg
Thorax 2000
Selective upregulation of a functional beta7 integrin on differentiating eosinophils
J Lundahl, R Sehmi, L Hayes, K Howie, JA Denburg
Allergy 2000
Role for cysteinyl leukotriene receptor antagonist therapy in asthma and their potential role in allergic rhinitis based on the concept of “one linked airway disease”
EO Meltzer
Annals of Allergy Asthma & Immunology 2000
Eosinophilopoiesis
J Denburg
Respiratory Medicine 2000
IL-5 production by bone marrow stromal cells: Implications for eosinophilia associated with asthma
MB Hogan, D Piktel, KS Landreth
Journal of Allergy and Clinical Immunology 2000
Molecular pathology of allergic disease
P Christodoulopoulos, L Cameron, S Durham, Q Hamid
Journal of Allergy and Clinical Immunology 2000
Systemic activation of basophils and eosinophils: Markers and consequences
BS Bochner
Journal of Allergy and Clinical Immunology 2000
Recruitment of T cells to the lung in response to antigen challenge
QA Hamid, LA Cameron
Journal of Allergy and Clinical Immunology 2000
Systemic aspects of allergic disease: Bone marrow responses
JA Denburg, R Sehmi, H Saito, J Pil-Seob, MD Inman, PM O’Byrne
Journal of Allergy and Clinical Immunology 2000
The effects of inhaled budesonide on circulating eosinophil progenitors and their expression of cytokines after allergen challenge in subjects with atopic asthma
GM Gauvreau, LJ Wood, R Sehmi, RM Watson, SC Dorman, RP Schleimer, JA Denburg, PM O'Byrne
American journal of respiratory and critical care medicine 2000
Interleukin-9 enhances interleukin-5 receptor expression, differentiation, and survival of human eosinophils
AS Gounni, B Gregory, E Nutku, F Aris, K Latifa, E Minshall, J North, J Tavernier, R Levit, N Nicolaides, D Robinson, Q Hamid
Blood 2000
Engagement of the CrkL Adapter in Interleukin-5 Signaling in Eosinophils
J Du, YM Alsayed, F Xin, SJ Ackerman, LC Platanias
The Journal of biological chemistry 2000
Evidence for Local Eosinophil Differentiation Within Allergic Nasal Mucosa: Inhibition with Soluble IL-5 Receptor
L Cameron, P Christodoulopoulos, F Lavigne, Y Nakamura, D Eidelman, A McEuen, A Walls, J Tavernier, E Minshall, R Moqbel, Q Hamid
Journal of immunology (Baltimore, Md. : 1950) 2000
Eosinophilopoiesis in A Murine Model of Allergic Airway Eosinophilia: Involvement of Bone Marrow IL-5 and IL-5 Receptor α
M Tomaki, LL Zhao, J Lundahl, M Sjöstrand, M Jordana, A Lindén, P OByrne, J Lötvall
Journal of immunology (Baltimore, Md. : 1950) 2000
Interleukin 5 regulates the isoform expression of its own receptor α-subunit
J Tavernier, JV der Heyden, A Verhee, G Brusselle, XV Ostade, J Vandekerckhove, J North, SM Rankin, AB Kay, DS Robinson
Blood 2000
Increased mature and immature CCR3 messenger RNA+ eosinophils in bone marrow from patients with atopic asthma compared with atopic and nonatopic control subjects
K Zeibecoglou, S Ying, T Yamada, J North, J Burman, J Bungre, Q Meng, AB Kay, DS Robinson
Journal of Allergy and Clinical Immunology 1999
Increased progenitor cell proliferation in the peripheral blood of patients with bronchial asthma: The role of nitric oxide
CH Wang, WY Hsieh, LY Shih, HC Lin, CY Liu, KF Chung, HP Kuo
Journal of Allergy and Clinical Immunology 1999
Cytokines in asthma
KF Chung, PJ Barnes
Thorax 1999
Interleukin-5 and allergic inflammation
OB yrne, W ood
Clinical & Experimental Allergy 1999
The nose, the lung and the bone marrow in allergic inflammation
J Denburg
Allergy 1999
Allergen challenge primes for IL-5 mRNA production and abrogates beta-adrenergic function in peripheral blood T lymphocytes from asthmatics
BORGER, JONKER, VELLENGA, POSTMA, DE MONCHY, KAUFFMAN
Clinical & Experimental Allergy 1999
Interaction between haemopoietic regulation and airway inflammation
PM O'byrne, GM Gauvreau, LJ Wood
Clinical & Experimental Allergy 1999
Bone marrow in atopy and asthma: hematopoietic mechanisms in allergic inflammation
JA Denburg
Immunology Today 1999
An inhaled corticosteroid, budesonide, reduces baseline but not allergen-induced increases in bone marrow inflammatory cell progenitors in asthmatic subjects
LJ Wood, R Sehmi, GM Gauvreau, RM Watson, R Foley, JA Denburg, PM O'byrne
American journal of respiratory and critical care medicine 1999
CD34 + /Interleukin-5R α Messenger RNA + Cells in the Bronchial Mucosa in Asthma: Potential Airway Eosinophil Progenitors
DS Robinson, R Damia, K Zeibecoglou, S Molet, J North, T Yamada, AB Kay, Q Hamid
American journal of respiratory cell and molecular biology 1999
Allergic Networks Regulating Eosinophilia
PS Foster
American journal of respiratory cell and molecular biology 1999
Immunolocalization of CD34 in Nasal Polyposis: Effect of Topical Corticosteroids
YK Kim, M Uno, DL Hamilos, L Beck, B Bochner, R Schleimer, JA Denburg
American journal of respiratory cell and molecular biology 1999
Circulating, but not local lung, IL-5 is required for the development of antigen-induced airways eosinophilia
J Wang, K Palmer, J Lŏtvall, S Milan, XF Lei, KI Matthaei, J Gauldie, MD Inman, M Jordana, Z Xing
Journal of Clinical Investigation 1998
Hemopoietic progenitors and cytokines in allergic inflammation
JA Denburg
Allergy 1998
Pharmacologic modulation of airway inflammation
PM O'Byrne, GM Gauvreau, LJ Wood
Allergy 1998
Inhibition by the anti-mitotic drug doxorubicin of platelet-activating-factor-induced late eosinophil accumulation in rats
S Perez, J Machado, R Cordeiro, M Martins, R Borojevic, P Silva
European Journal of Pharmacology 1998
Enhanced Expression of GM-CSF in Differentiating Eosinophils of Atopic and Atopic Asthmatic Subjects
GM Gauvreau, PM O'Byrne, R Moqbel, J Velazquez, RM Watson, KJ Howie, JA Denburg
American journal of respiratory cell and molecular biology 1998
The mechanism of IL-5 signal transduction
T Adachi, R Alam
American journal of physiology. Cell physiology 1998

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