Research Article
B Ludvik, J J Nolan, A Roberts, J Baloga, M Joyce, J M Bell, J M Olefsky
Title and authors | Publication | Year |
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Evolution of the diagnostic value of "the sugar of the blood": hitting the sweet spot to identify alterations in glucose dynamics.
Magkos F, Reeds DN, Mittendorfer B |
Physiological reviews | 2022 |
Profound Sensitivity of the Liver to the Direct Effect of Insulin Allows Peripheral Insulin Delivery to Normalize Hepatic but Not Muscle Glucose Uptake in the Healthy Dog
Kraft G, Coate KC, Smith M, Farmer B, Scott M, Hastings J, Cherrington AD, Edgerton DS |
Diabetes | 2022 |
The Importance of the Mechanisms by Which Insulin Regulates Meal-Associated Liver Glucose Uptake in the Dog
G Kraft, KC Coate, M Smith, B Farmer, M Scott, AD Cherrington, DS Edgerton |
Diabetes | 2021 |
Importance of the route of insulin delivery to its control of glucose metabolism
DS Edgerton, MC Moore, JM Gregory, G Kraft, AD Cherrington |
American journal of physiology. Endocrinology and metabolism | 2021 |
Exercise-Induced Improvements to Whole Body Glucose Metabolism in Type 2 Diabetes: The Essential Role of the Liver
SO Warner, MV Yao, RL Cason, JJ Winnick |
Frontiers in Endocrinology | 2020 |
Targeting insulin to the liver corrects defects in glucose metabolism caused by peripheral insulin delivery
Dale Edgerton, scott melanie, Ben Farmer, Phil Williams, Peter Madsen, Thomas Kjeldsen, Christian L. Brand, Christian Fledelius, Erica Nishimura, Alan Cherrington |
JCI Insight | 2019 |
Aerobic exercise training improves hepatic and muscle insulin sensitivity, but reduces splanchnic glucose uptake in obese humans with type 2 diabetes
JM Gregory, JA Muldowney, BG Engelhardt, R Tyree, P Marks-Shulman, HJ Silver, EP Donahue, DS Edgerton, JJ Winnick |
Nutrition and Diabetes | 2019 |
Correcting Postprandial Hyperglycemia in Zucker Diabetic Fatty Rats With an SGLT2 Inhibitor Restores Glucose Effectiveness in the Liver and Reduces Insulin Resistance in Skeletal Muscle
TP OBrien, EC Jenkins, SK Estes, AV Castaneda, K Ueta, TD Farmer, AE Puglisi, LL Swift, RL Printz, M Shiota |
Diabetes | 2017 |
Two weeks of moderate-intensity continuous training, but not high-intensity interval training, increases insulin-stimulated intestinal glucose uptake
KK Motiani, AM Savolainen, JJ Eskelinen, J Toivanen, T Ishizu, M Yli-Karjanmaa, KA Virtanen, R Parkkola, J Kapanen, TJ Grönroos, M Haaparanta-Solin, O Solin, N Savisto, M Ahotupa, E Löyttyniemi, J Knuuti, P Nuutila, KK Kalliokoski, JC Hannukainen |
Journal of applied physiology | 2017 |
Low Glycemic Index Prototype Isomaltulose—Update of Clinical Trials
CC Maresch, SF Petry, S Theis, A Bosy-Westphal, T Linn |
Nutrients | 2017 |
Endocrinology: Adult and Pediatric
M Gurnell, TJ Visser, P Beck-Peccoz, VK Chatterjee |
Endocrinology: Adult and Pediatric | 2016 |
Accurate Measurement of Postprandial Glucose Turnover: Why Is It Difficult and How Can It Be Done (Relatively) Simply?
RA Rizza, G Toffolo, C Cobelli |
Diabetes | 2016 |
Endocrinology
C Napier, SH Pearce |
Endocrinology | 2016 |
Metabolic Response of Slowly Absorbed Carbohydrates in Type 2 Diabetes Mellitus
M Ang |
2016 | |
Gastric bypass alters both glucose-dependent and glucose-independent regulation of islet hormone secretion: Islet Hormone Secretion at Sub-Basal Glucose in GB
M Salehi, SC Woods, DA D'Alessio |
Obesity | 2015 |
Comparison of the effects of slowly and rapidly absorbed carbohydrates on postprandial glucose metabolism in type 2 diabetes mellitus patients: a randomized trial
M Ang, T Linn |
The American journal of clinical nutrition | 2014 |
Strategies for the design of hepatoselective glucokinase activators to treat type 2 diabetes
JA Pfefferkorn |
Expert Opinion on Drug Discovery | 2013 |
Portal Vein Glucose Entry Triggers a Coordinated Cellular Response That Potentiates Hepatic Glucose Uptake and Storage in Normal but Not High-Fat/High-Fructose–Fed Dogs
KC Coate, G Kraft, JM Irimia, MS Smith, B Farmer, DW Neal, PJ Roach, M Shiota, AD Cherrington |
Diabetes | 2012 |
Liver glycogen loading dampens glycogen synthesis seen in response to either hyperinsulinemia or intraportal glucose infusion
JJ Winnick, Z An, G Kraft, CJ Ramnanan, JM Irimia, M Smith, M Lautz, PJ Roach, AD Cherrington |
Diabetes | 2012 |
Hepatic Glycogen Supercompensation Activates AMP-Activated Protein Kinase, Impairs Insulin Signaling, and Reduces Glycogen Deposition in the Liver
JJ Winnick, Z An, CJ Ramnanan, M Smith, JM Irimia, DW Neal, MC Moore, PJ Roach, AD Cherrington |
Diabetes | 2011 |
The Metabolic Syndrome
S Devaraj, D Siegel, I Jialal |
The Metabolic Syndrome | 2011 |
Computational assessment of insulin secretion and insulin sensitivity from 2-h oral glucose tolerance tests for clinical use for type 2 diabetes
M Seike, T Saitou, Y Kouchi, T Ohara, M Matsuhisa, K Sakaguchi, K Tomita, K Kosugi, A Kashiwagi, M Kasuga, M Tomita, Y Naito, H Nakajima |
The journal of physiological sciences : JPS | 2011 |
Modeling of 24-Hour Glucose and Insulin Profiles of Patients With Type 2 Diabetes
PM Jauslin, N Frey, MO Karlsson |
The Journal of Clinical Pharmacology | 2011 |
Glucose flux in controlled hyperglycaemia before and after oral glucose ingestion in men with mild type 2 diabetes
V Rigalleau, MC Beauvieux, JL Gallis, H Gin, P Schneiter, L Tappy |
Diabetes & Metabolism | 2010 |
Portal glucose infusion-glucose clamp measures hepatic influence on postprandial systemic glucose appearance as well as whole body glucose disposal
D Zheng, V Ionut, V Mooradian, D Stefanovski, RN Bergman |
American journal of physiology. Endocrinology and metabolism | 2010 |
Nutrition, Diet Therapy, and the Liver
J Kondrup |
Nutrition, Diet Therapy, and the Liver | 2009 |
Portal infusion of escitalopram enhances hepatic glucose disposal in conscious dogs
Z An, MC Moore, JJ Winnick, B Farmer, DW Neal, M Lautz, M Smith, T Rodewald, AD Cherrington |
European Journal of Pharmacology | 2009 |
A physiological increase in the hepatic glycogen level does not affect the response of net hepatic glucose uptake to insulin
JJ Winnick, Z An, MC Moore, CJ Ramnanan, B Farmer, M Shiota, AD Cherrington |
American journal of physiology. Endocrinology and metabolism | 2009 |
Impact of visceral adipose tissue on liver metabolism and insulin resistance. Part II: Visceral adipose tissue production and liver metabolism
J Girard, M Lafontan |
Diabetes & Metabolism | 2008 |
Simulation and initial proof-of-concept validation of a glycaemic regulation algorithm in critical care
JG Chase, XW Wong, I Singh-Levett, LJ Hollingsworth, CE Hann, GM Shaw, T Lotz, J Lin |
Control Engineering Practice | 2008 |
Exenatide Sensitizes Insulin-Mediated Whole-Body Glucose Disposal and Promotes Uptake of Exogenous Glucose by the Liver
D Zheng, V Ionut, V Mooradian, D Stefanovski, RN Bergman |
Diabetes | 2008 |
Mechanism of action of exenatide to reduce postprandial hyperglycemia in type 2 diabetes
A Cervera, E Wajcberg, A Sriwijitkamol, M Fernandez, P Zuo, C Triplitt, N Musi, RA DeFronzo, E Cersosimo |
American journal of physiology. Endocrinology and metabolism | 2008 |
The Role of α-Cell Dysregulation in Fasting and Postprandial Hyperglycemia in Type 2 Diabetes and Therapeutic Implications
BE Dunning, JE Gerich |
Endocrine reviews | 2007 |
Effects of Diet-Induced Moderate Weight Reduction on Intrahepatic and Intramyocellular Triglycerides and Glucose Metabolism in Obese Subjects
F Sato, Y Tamura, H Watada, N Kumashiro, Y Igarashi, H Uchino, T Maehara, S Kyogoku, S Sunayama, H Sato, T Hirose, Y Tanaka, R Kawamori |
The Journal of clinical endocrinology and metabolism | 2007 |
Sweet Clarity: Less Invasive Measures of Hepatic Glucose Metabolism
EJ Fine, DE Lee, M Hawkins |
Gastroenterology | 2007 |
Étiologie et physiopathologie du diabète de type 2
V Rigalleau, J Lang, H Gin |
EMC - Endocrinologie - Nutrition | 2007 |
An Integrated Glucose-Insulin Model to Describe Oral Glucose Tolerance Test Data in Type 2 Diabetics
PM Jauslin, HE Silber, N Frey, R Gieschke, US Simonsson, K Jorga, MO Karlsson |
The Journal of Clinical Pharmacology | 2007 |
A defect in glucose-induced dissociation of glucokinase from the regulatory protein in Zucker diabetic fatty rats in the early stage of diabetes
JS Shin, TP Torres, RE Catlin, EP Donahue, M Shiota |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2007 |
Mechanisms of Insulin Action
AR Saltiel, JE Pessin |
2007 | |
Glucose Toxicity Is Responsible for the Development of Impaired Regulation of Endogenous Glucose Production and Hepatic Glucokinase in Zucker Diabetic Fatty Rats
Y Fujimoto, TP Torres, EP Donahue, M Shiota |
2006 | |
A Novel, Model-Based Insulin and Nutrition Delivery Controller for Glycemic Regulation in Critically Ill Patients
XW Wong, I Singh-Levett, LJ Hollingsworth, GM Shaw, CE Hann, T Lotz, J Lin, OS Wong, JG Chase |
Diabetes Technology & Therapeutics | 2006 |
A Pilot Study of the SPRINT Protocol for Tight Glycemic Control in Critically Ill Patients
T Lonergan, AL Compte, M Willacy, JG Chase, GM Shaw, CE Hann, T Lotz, J Lin, XW Wong |
Diabetes Technology & Therapeutics | 2006 |
Targeting postprandial hyperglycemia
MS Rendell, L Jovanovic |
Metabolism | 2006 |
Model predictive glycaemic regulation in critical illness using insulin and nutrition input: A pilot study
XW Wong, JG Chase, GM Shaw, CE Hann, T Lotz, J Lin, I Singh-Levett, LJ Hollingsworth, OS Wong, S Andreassen |
Medical engineering & physics | 2006 |
Mechanisms for abnormal postprandial glucose metabolism in type 2 diabetes
HJ Woerle, E Szoke, C Meyer, JM Dostou, SD Wittlin, NR Gosmanov, SL Welle, JE Gerich |
American journal of physiology. Endocrinology and metabolism | 2005 |
Inclusion of low amounts of fructose with an intraportal glucose load increases net hepatic glucose uptake in the presence of relative insulin deficiency in dog
M Shiota, P Galassetti, K Igawa, DW Neal, AD Cherrington |
American journal of physiology. Endocrinology and metabolism | 2005 |
Abnormal renal, hepatic, and muscle glucose metabolism following glucose ingestion in type 2 diabetes
C Meyer, HJ Woerle, JM Dostou, SL Welle, JE Gerich |
American journal of physiology. Endocrinology and metabolism | 2004 |
The Cellular Fate of Glucose and Its Relevance in Type 2 Diabetes
C Bouché, S Serdy, CR Kahn, AB Goldfine |
Endocrine reviews | 2004 |
Pathogenesis of type 2 diabetes mellitus
RA DeFronzo |
Medical Clinics of North America | 2004 |
Acute elevation of free fatty acids impairs hepatic glucose uptake in conscious rats
I Nakahara, M Matsuhisa, Y Shiba, A Kuroda, Y Nakatani, M Hatazaki, Y Kajimoto, M Kubota, Y Yamasaki, M Hori |
Diabetes Research and Clinical Practice | 2004 |
Defect in glucokinase translocation in Zucker diabetic fatty rats
Y Fujimoto, EP Donahue, M Shiota |
American journal of physiology. Endocrinology and metabolism | 2004 |
International Textbook of Diabetes Mellitus
RA DeFronzo, L Mandarino, E Ferrannini |
International Textbook of Diabetes Mellitus | 2003 |
Pioglitazone Reduces Hepatic Fat Content and Augments Splanchnic Glucose Uptake in Patients With Type 2 Diabetes
M Bajaj, S Suraamornkul, T Pratipanawatr, LJ Hardies, W Pratipanawatr, L Glass, E Cersosimo, Y Miyazaki, RA DeFronzo |
Diabetes | 2003 |
Fetal programming of perivenous glucose uptake reveals a regulatory mechanism governing hepatic glucose output during refeeding
HC Murphy, G Regan, IG Bogdarina, AJ Clark, RA Iles, RD Cohen, GA Hitman, CL Berry, Z Coade, CJ Petry, SP Burns |
Diabetes | 2003 |
Nonesterified fatty acids and hepatic glucose metabolism in the conscious dog
Mary Courtney Moore, Shosuke Satake, Margaret Lautz, Scott A Soleimanpour, Doss W Neal, Marta Smith, Alan D Cherrington |
Diabetes | 2003 |
Pathogenesis of hyperglycaemia in type 2 diabetes
A Mitrakou |
Diabetes, Obesity and Metabolism | 2002 |
Inclusion of low amounts of fructose with an intraduodenal glucose load markedly reduces postprandial hyperglycemia and hyperinsulinemia in the conscious dog
M Shiota, MC Moore, P Galassetti, M Monohan, DW Neal, GI Shulman, AD Cherrington |
Diabetes | 2002 |
Free Fatty Acids Reduce Splanchnic and Peripheral Glucose Uptake in Patients With Type 2 Diabetes
M Bajaj, T Pratipanawatr, R Berria, W Pratipanawatr, S Kashyap, K Cusi, L Mandarino, RA DeFronzo |
Diabetes | 2002 |
Influence of metabolic control on splanchnic glucose uptake, insulin sensitivity, and the time required for glucose absorption in patients with type 1 diabetes
Petra Georg, Alexandra Kautzky-Willer, Katja Mahdjoobian, Astrid Hofer, Rudolf Prager, Giovanni Pacini, Bernhard H Ludvik |
Diabetes care | 2002 |
Type 2 diabetes impairs splanchnic uptake of glucose but does not alter intestinal glucose absorption during enteral glucose feeding: additional evidence for a defect in hepatic glucokinase activity
A Basu, R Basu, P Shah, A Vella, CM Johnson, M Jensen, KS Nair, WF Schwenk, RA Rizza |
Diabetes | 2001 |
In Normal Men, Free Fatty Acids Reduce Peripheral but Not Splanchnic Glucose Uptake
V Rigalleau, C Binnert, K Minehira, N Stefanoni, P Schneiter, E Henchoz, O Matzinger, C Cayeux, E Jequier, L Tappy |
Diabetes | 2001 |
POSTPRANDIAL HEPATIC GLYCOGEN SYNTHESIS IN LIVER TRANSPLANT RECIPIENTS1
P Schneiter, M Gillet, R Chiol??ro, JP Wauters, M Berger, L Tappy |
Transplantation | 2000 |
Hepatic nonoxidative disposal of an oral glucose meal in patients with liver cirrhosis
P Schneiter, M Gillet, R Chioléro, E Jéquier, L Tappy |
Metabolism | 1999 |
Euglycemic hyperinsulinemic clamp to assess posthepatic glucose appearance after carbohydrate loading. 1. Validation in pigs
V Lang, P Vaugelade, F Bernard, B Darcy-Vrillon, C Alamowitch, G Slama, PH Duée, FR Bornet |
The American journal of clinical nutrition | 1999 |
Regulation of endogenous glucose production by glucose per se is impaired in type 2 diabetes mellitus
M Mevorach, A Giacca, Y Aharon, M Hawkins, H Shamoon, L Rossetti |
Journal of Clinical Investigation | 1998 |