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Citations to this article

Changes in gene expression in the intact human heart. Downregulation of alpha-myosin heavy chain in hypertrophied, failing ventricular myocardium.
B D Lowes, … , E M Gilbert, M R Bristow
B D Lowes, … , E M Gilbert, M R Bristow
Published November 1, 1997
Citation Information: J Clin Invest. 1997;100(9):2315-2324. https://doi.org/10.1172/JCI119770.
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Research Article Article has an altmetric score of 9

Changes in gene expression in the intact human heart. Downregulation of alpha-myosin heavy chain in hypertrophied, failing ventricular myocardium.

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Research Article

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B D Lowes, W Minobe, W T Abraham, M N Rizeq, T J Bohlmeyer, R A Quaife, R L Roden, D L Dutcher, A D Robertson, N F Voelkel, D B Badesch, B M Groves, E M Gilbert, M R Bristow

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KN Goss, AR Cucci, AJ Fisher, M Albrecht, A Frump, R Tursunova, Y Gao, MB Brown, I Petrache, RS Tepper, SK Ahlfeld, T Lahm
American journal of physiology. Lung cellular and molecular physiology 2015
Aerobic exercise training promotes physiological cardiac remodeling involving a set of microRNAs
T Fernandes, VG Baraúna, CE Negrão, MI Phillips, EM Oliveira
American journal of physiology. Heart and circulatory physiology 2015
Antagonistic regulation of mRNA expression and splicing by CELF and MBNL proteins
ET Wang, AJ Ward, JM Cherone, J Giudice, TT Wang, DJ Treacy, NJ Lambert, P Freese, T Saxena, TA Cooper, CB Burge
Genome research 2015
Towards adult-like human engineered cardiac tissue
NT Feric, M Radisic
Advanced Drug Delivery Reviews 2015
Adult mice expressing a Braf Q241R mutation on an ICR/CD-1 background exhibit a cardio-facio-cutaneous syndrome phenotype
M Moriya, S Inoue, S Miyagawa-Tomita, Y Nakashima, D Oba, T Niihori, M Hashi, H Ohnishi, S Kure, Y Matsubara, Y Aoki
Human Molecular Genetics 2015
Prospects for In Vitro Myofilament Maturation in Stem Cell-Derived Cardiac Myocytes
Schwan, S Campbell
Biomarker insights 2015
Cardiac Transcriptome and Dilated Cardiomyopathy Genes in Zebrafish
YH Shih, Y Zhang, Y Ding, CA Ross, H Li, TM Olson, X Xu
Circulation. Cardiovascular genetics 2015
Sarcomeric protein isoform transitions in cardiac muscle: A journey to heart failure
Z Yin, J Ren, W Guo
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2015
Sympathetic nervous system activation and β-adrenoceptor blockade in right heart failure: Sympathetic activation and β-blockers in RHF
S Andersen, A Andersen, FS de Man, JE Nielsen-Kudsk
European Journal of Heart Failure 2015
Animal model of reversible, right ventricular failure
SH McKellar, H Javan, ME Bowen, X Liu, CL Schaaf, CM Briggs, H Zou, AD Gomez, OM Abdullah, EW Hsu, CH Selzman
Journal of Surgical Research 2015
Human umbilical cord blood-derived mononuclear cells improve murine ventricular function upon intramyocardial delivery in right ventricular chronic pressure overload
S Oommen, S Yamada, SC Peral, KA Campbell, E S.Bruinsma, A Terzic, TJ Nelson
Stem Cell Research & Therapy 2015
Advancing knowledge of right ventricular pathophysiology in chronic pressure overload: Insights from experimental studies
J Guihaire, PE Noly, S Schrepfer, O Mercier
Archives of Cardiovascular Diseases 2015
The adrenergic system in pulmonary arterial hypertension: bench to bedside (2013 Grover Conference series)
MR Bristow, RA Quaife
Pulmonary circulation 2015
MicroRNA in Regenerative Medicine
A Magenta, A Rossini, P Fasanaro, G Pompilio, MC Capogrossi
MicroRNA in Regenerative Medicine 2015
Current Advances in Noncoding RNA Relevant to Epigenetic Mechanisms
P Mathiyalagan, AW Khan, XJ Du, A El-Osta
Current Molecular Biology Reports 2015
Cellular and molecular basis of RV hypertrophy in congenital heart disease
D Iacobazzi, MS Suleiman, M Ghorbel, SJ George, M Caputo, RM Tulloh
Heart (British Cardiac Society) 2015
The Right Ventricle: A Comprehensive Review From Anatomy, Physiology, and Mechanics to Hemodynamic, Functional, and Imaging Evaluation
A Sadeghpour, A Alizadehasl
Archives of Cardiovascular Imaging 2015
Adaptive capacity of the right ventricle: why does it fail?
EM Poels, PA da Martins, VP van Empel
American journal of physiology. Heart and circulatory physiology 2015
Effect of vildagliptin, a dipeptidyl peptidase 4 inhibitor, on cardiac hypertrophy induced by chronic beta-adrenergic stimulation in rats
T Miyoshi, K Nakamura, M Yoshida, D Miura, H Oe, S Akagi, H Sugiyama, K Akazawa, T Yonezawa, J Wada, H Ito
Cardiovascular Diabetology 2014
Gene expression and β-adrenergic signaling are altered in hypoplastic left heart syndrome
SD Miyamoto, BL Stauffer, J Polk, A Medway, M Friedrich, K Haubold, V Peterson, K Nunley, P Nelson, R Sobus, KR Stenmark, CC Sucharov
The Journal of Heart and Lung Transplantation 2014
N-acetylcysteine improves established monocrotaline-induced pulmonary hypertension in rats
MC Chaumais, B Ranchoux, D Montani, P Dorfmüller, L Tu, F Lecerf, N Raymond, C Guignabert, L Price, G Simonneau, S Cohen-Kaminsky, M Humbert, F Perros
Respiratory Research 2014
Acquisition of a Quantitative, Stoichiometrically Conserved Ratiometric Marker of Maturation Status in Stem Cell-Derived Cardiac Myocytes
FB Bedada, SS Chan, SK Metzger, L Zhang, J Zhang, DJ Garry, TJ Kamp, M Kyba, JM Metzger
Stem Cell Reports 2014
Nitroxyl (HNO) for Treatment of Acute Heart Failure
A Arcaro, G Lembo, CG Tocchetti
Current Heart Failure Reports 2014
The study of fetal rat model of intra-amniotic isoproterenol injection induced heart dysfunction and phenotypic switch of contractile proteins
Y Li, J Fang, Y Hua, C Wang, D Mu, K Zhou
BioMed Research International 2014
Is cardiac resynchronization therapy for right ventricular failure in pulmonary arterial hypertension of benefit?
JT Rasmussen, T Thenappan, DG Benditt, EK Weir, MR Pritzker
Pulmonary circulation 2014
Right ventricular remodeling in idiopathic pulmonary arterial hypertension: adaptive versus maladaptive morphology
R Badagliacca, R Poscia, B Pezzuto, M Nocioni, M Mezzapesa, M Francone, E Giannetta, S Papa, C Gambardella, S Sciomer, M Volterrani, F Fedele, CD Vizza
The Journal of Heart and Lung Transplantation 2014
Right ventricular plasticity in a porcine model of chronic pressure overload
J Guihaire, F Haddad, D Boulate, A Capderou, B Decante, E Flécher, S Eddahibi, P Dorfmüller, P Hervé, M Humbert, JP Verhoye, P Dartevelle, O Mercier, E Fadel
The Journal of Heart and Lung Transplantation 2014
Chromatin modifications remodel cardiac gene expression
P Mathiyalagan, ST Keating, XJ Du, A El-Osta
Cardiovascular Research 2014
Right Ventricular Dyssynchrony in Idiopathic Pulmonary Arterial Hypertension: Determinants and Impact on Pump Function
R Badagliacca, R Poscia, B Pezzuto, S Papa, C Gambardella, M Francone, M Mezzapesa, M Nocioni, A Nona, R Rosati, S Sciomer, F Fedele, CD Vizza
The Journal of Heart and Lung Transplantation 2014
Effects of Bisoprolol and Losartan Treatment in the Hypertrophic and Failing Right Heart
S Andersen, JG Schultz, A Andersen, S Ringgaard, JM Nielsen, S Holmboe, MD Vildbrad, FS de Man, HJ Bogaard, A Vonk-Noordegraaf, JE Nielsen-Kudsk
Journal of Cardiac Failure 2014
Antithetical Regulation of α-Myosin Heavy Chain Between Fetal and Adult Heart Failure Though Shuttling of HDAC5 Regulating YY-1 Function
J Fang, Y Li, K Zhou, Y Hua, C Wang, D Mu
Cardiovascular Toxicology 2014
Reference Module in Biomedical Sciences
DL Sackett, RB Haynes
2014
Right ventricular reserve in a piglet model of chronic pulmonary hypertension
J Guihaire, F Haddad, PE Noly, D Boulate, B Decante, P Dartevelle, M Humbert, JP Verhoye, O Mercier, E Fadel
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2014
Aging and Heart Failure
BI Jugdutt
2014
The Right Heart
SP Gaine, R Naeije, AJ Peacock
2014
Pressure-overload-induced right heart failure
S Rain, ML Handoko, AV Noordegraaf, HJ Bogaard, J van der Velden, FS de Man
Pflügers Archiv - European Journal of Physiology 2014
Right Ventricular Failure and Pathobiology in Patients with Congenital Heart Disease - Implications for Long-Term Follow-Up
D Köhler, R Arnold, T Loukanov, M Gorenflo
Frontiers in Pediatrics 2013
Assessment and treatment of right ventricular failure
MA Simon
Nature Reviews Cardiology 2013
Embryonically induced β-catenin haploinsufficiency attenuates postnatal heart development and causes violation of foetal genes program
OL Palchevska, VV Balatskii, AO Andrejeva, LL Macewicz, OO Piven, LL Lukash
Biopolymers and Cell 2013
Increase in cardiac myosin heavy-chain (MyHC) alpha protein isoform in hibernating ground squirrels, with echocardiographic visualization of ventricular wall hypertrophy and prolonged contraction
OL Nelson, BC Rourke
The Journal of experimental biology 2013
Right Heart Adaptation to Pulmonary Arterial Hypertension
A Vonk-Noordegraaf, F Haddad, KM Chin, PR Forfia, SM Kawut, J Lumens, R Naeije, J Newman, RJ Oudiz, S Provencher, A Torbicki, NF Voelkel, PM Hassoun
Journal of the American College of Cardiology 2013
Engineering Cardiac Tissues from Pluripotent Stem Cells for Drug Screening and Studies of Cell Maturation
JW Miklas, SS Nunes, M Radisic
Israel Journal of Chemistry 2013
M-Protein Is Down-Regulated in Cardiac Hypertrophy Driven by Thyroid Hormone in Rats
A Rozanski, AP Takano, PN Kato, AG Soares, C Lellis-Santos, JC Campos, JC Ferreira, ML Barreto-Chaves, AS Moriscot
Molecular Endocrinology 2013
MAP kinase kinase kinase-2 (MEKK2) regulates hypertrophic remodeling of the right ventricle in hypoxia-induced pulmonary hypertension
RD Brown, SK Ambler, M Li, TM Sullivan, LN Henry, JT Crossno, CS Long, TP Garrington, KR Stenmark
American journal of physiology. Heart and circulatory physiology 2013
Textbook of Cardiovascular Intervention
CA Thompson
2013
Lost in transgenesis: a user's guide for genetically manipulating the mouse in cardiac research
J Davis, M Maillet, JM Miano, JD Molkentin
Circulation research 2012
Metformin Rescues the Myocardium from Doxorubicin-Induced Energy Starvation and Mitochondrial Damage in Rats
AE Ashour, MM Sayed-Ahmed, AR Abd-Allah, HM Korashy, ZH Maayah, H Alkhalidi, M Mubarak, A Alhaider
Oxidative medicine and cellular longevity 2012
Pulmonary Hypertension
MH Park, MR Mehra
Journal of the American College of Cardiology 2012
MicroRNAs in control of cardiac hypertrophy
PA da Martins, LJ de Windt
Cardiovascular Research 2012
Remodeling of rat cardiomyocytes after neonatal cryptosporidiosis. I. Change of ratio of isoforms of myosin heavy chains
OV Anatskaya, IV Matveev, NV Sidorenko, MV Kharchenko, AV Kropotov, AE Vinogradov
Cell and Tissue Biology 2012
Muscle
ML Martin, SL Belmonte, R Ram, FA Kamal, BC Blaxall
Muscle 2012
Right Ventricular Performance in Chronic Congestive Heart Failure
GT Sayer, MJ Semigran
Cardiology Clinics 2012
Two distinct phosphorylation events govern the function of muscle FHOD3
T Iskratsch, S Reijntjes, J Dwyer, P Toselli, IR Dégano, I Dominguez, E Ehler
Cellular and Molecular Life Sciences 2012
Remodeling of rat cardiomyocytes after neonatal cryptosporidiosis. II. Deformation, excessive polyploidization, and HIF-1α overexpression
OV Anatskaya, NV Sidorenko, IV Matveev, AV Kropotov, AE Vinogradov
Cell and Tissue Biology 2012
Actualités dans la prise en charge des patients atteints d’hypertension pulmonaire en 2012
S Duong-Quy
Revue des Maladies Respiratoires Actualités 2012
Hormonal regulation of  -myosin heavy chain expression in the mouse left ventricle
M Patrizio, M Musumeci, A Piccone, C Raggi, E Mattei, G Marano
Journal of Endocrinology 2012
The Right Heart in Congenital Heart Disease, Mechanisms and Recent Advances
J Guihaire, F Haddad, O Mercier, DJ Murphy, JC Wu, E Fadel
Journal of Clinical & Experimental Cardiology 2012
MAP kinase kinase kinase-2 (MEKK2) regulates hypertrophic remodeling of the right ventricle in hypoxia-induced pulmonary hypertension
RD Brown, SK Ambler, M Li, TM Sullivan, LN Henry, JT Crossno, CS Long, TP Garrington, KR Stenmark
American journal of physiology. Heart and circulatory physiology 2012
Dynamic link between histone H3 acetylation and an increase in the functional characteristics of human ESC/iPSC-derived cardiomyocytes
TG Otsuji, Y Kurose, H Suemori, M Tada, N Nakatsuji
PloS one 2012
Transgenic rabbit models for studying human cardiovascular diseases
X Peng
Comparative medicine 2012
Dynamic Link between Histone H3 Acetylation and an Increase in the Functional Characteristics of Human ESC/iPSC-Derived Cardiomyocytes
TG Otsuji, Y Kurose, H Suemori, M Tada, N Nakatsuji, D Kaufman
PloS one 2012
Right ventricular plasticity and functional imaging
EL Brittain, AR Hemnes, M Keebler, M Lawson, BF Byrd, T DiSalvo
Pulmonary circulation 2012
Therapeutic Inhibition of miR-208a Improves Cardiac Function and Survival During Heart Failure
RL Montgomery, TG Hullinger, HM Semus, BA Dickinson, AG Seto, JM Lynch, C Stack, PA Latimer, EN Olson, E Rooij
Circulation 2011
Comprehensive Physiology
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Molecular signature of a right heart failure program in chronic severe pulmonary hypertension
JI Drake, HJ Bogaard, S Mizuno, B Clifton, B Xie, Y Gao, CI Dumur, P Fawcett, NF Voelkel, R Natarajan
American journal of respiratory cell and molecular biology 2011
IQGAP1 regulates ERK1/2 and AKT signalling in the heart and sustains functional remodelling upon pressure overload
M Sbroggiò, D Carnevale, A Bertero, G Cifelli, ED Blasio, G Mascio, E Hirsch, WF Bahou, E Turco, L Silengo, M Brancaccio, G Lembo, G Tarone
Cardiovascular Research 2011
Investigating the purpose of prelamin A processing
BS Davies, C Coffinier, SH Yang, RH Barnes, HJ Jung, SG Young, LG Fong
Nucleus 2011
Comprehensive Physiology
NF Voelkel, R Natarajan, JI Drake, HJ Bogaard
Comprehensive Physiology 2011
Cellular mechanisms of cardiomyopathy
PA Harvey, LA Leinwand
The Journal of Cell Biology 2011
Estrogen Rescues Preexisting Severe Pulmonary Hypertension in Rats
S Umar, A Iorga, H Matori, RD Nadadur, J Li, F Maltese, A der Laarse, M Eghbali
American journal of respiratory and critical care medicine 2011
A high-performance liquid chromatography assay for quantification of cardiac myosin heavy chain isoform protein expression
DD Lemon, PJ Papst, K Joly, CF Plato, TA McKinsey
Analytical Biochemistry 2011
Bradykinin and the Heart: Left, Right, or Both?
T Lahm
Journal of Surgical Research 2011
Atrial septostomy in patients with pulmonary hypertension: should it be recommended?
AE Lammers, SG Haworth, GP Diller
Expert Review of Respiratory Medicine 2011
Reverse Remodelling and Recovery from Heart Failure Are Associated with Complex Patterns of Gene Expression
LE Felkin, EA Lara-Pezzi, JL Hall, EJ Birks, PJ Barton
Journal of Cardiovascular Translational Research 2011
Perioperative Management of Pulmonary Hypertension in Children with Critical Heart Disease
RA Bronicki
Current Treatment Options in Cardiovascular Medicine 2011
A Cellular MicroRNA, let-7i, Is a Novel Biomarker for Clinical Outcome in Patients With Dilated Cardiomyopathy
M Satoh, Y Minami, Y Takahashi, T Tabuchi, M Nakamura
Journal of Cardiac Failure 2011
Different Patterns of Adaptation of the Right Ventricle to Pressure Overload: A Comparison between Pulmonary Hypertension and Pulmonary Stenosis
R Jurcut, S Giusca, R Ticulescu, E Popa, MS Amzulescu, I Ghiorghiu, IM Coman, BA Popescu, JU Voigt, C Ginghina
Journal of the American Society of Echocardiography 2011
Evidence of diminished coronary flow in pulmonary hypertension - explaining angina pectoris in this patient group?
JW Koskenvuo, R Mirsky, Y Zhang, H Helenius, FS Angeli, TD Marco, AJ Boyle, Y Yeghiazarians
Clinical Physiology and Functional Imaging 2011
Prolonged overcirculation-induced pulmonary arterial hypertension as a cause of right ventricular failure
B Rondelet, C Dewachter, F Kerbaul, X Kang, P Fesler, S Brimioulle, R Naeije, L Dewachter
European Heart Journal 2011
Effects of low-level α-myosin heavy chain expression on contractile kinetics in porcine myocardium
MR Locher, MV Razumova, JE Stelzer, HS Norman, RL Moss
American journal of physiology. Heart and circulatory physiology 2011
Heart Failure: A Companion to Braunwald's Heart Disease
A Diwan, GW Dorn
Heart Failure: A Companion to Braunwald's Heart Disease 2011
Myocardial performance and its acute response to angiotensin II infusion in fetal sheep adapted to chronic anemia
LS Bernard, JN Hashima, AR Hohimer, DJ Sahn, M Ashraf, O Vuolteenaho, LE Davis, J Rasanen
Reproductive sciences (Thousand Oaks, Calif.) 2011
Right Ventricular Dysfunction and Failure in Chronic Pressure Overload
MA Simon, MR Pinsky
Cardiology Research and Practice 2011
Effects of low-level α-myosin heavy chain expression on contractile kinetics in porcine myocardium
MR Locher, MV Razumova, JE Stelzer, HS Norman, RL Moss
American journal of physiology. Heart and circulatory physiology 2011
The UNC-45 Chaperone Is Critical for Establishing Myosin-Based Myofibrillar Organization and Cardiac Contractility in the Drosophila Heart Model
GC Melkani, R Bodmer, K Ocorr, SI Bernstein, E Abraham
PloS one 2011
Heart failure and mouse models
R Breckenridge
Disease models & mechanisms 2010
An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria
BS Davies, RH 2nd, Y Tu, S Ren, DA Andres, HP Spielmann, J Lammerding, Y Wang, SG Young, LG Fong
Human Molecular Genetics 2010
MicroRNAs in cardiac hypertrophy: angels or devils
SL Ding, LY Zhou, PF Li
Wiley Interdisciplinary Reviews: RNA 2010
Chromatin regulation by Brg1 underlies heart muscle development and disease
CT Hang, J Yang, P Han, HL Cheng, C Shang, E Ashley, B Zhou, CP Chang
Nature 2010
Effects of myosin heavy chain manipulation in experimental heart failure
J James, K Hor, MA Moga, LA Martin, J Robbins
Journal of Molecular and Cellular Cardiology 2010
β-adrenergic blockade attenuates cardiac dysfunction and myofibrillar remodelling in congestive heart failure
J Machackova, SK Sanganalmath, V Elimban, NS Dhalla
Journal of Cellular and Molecular Medicine 2010
New insights for the diagnosis and management of right ventricular failure, from molecular imaging to targeted right ventricular therapy
F Haddad, E Ashley, ED Michelakis
Current Opinion in Cardiology 2010
PI3K kinase and scaffold functions in heart
F Damilano, A Perino, E Hirsch
Annals of the New York Academy of Sciences 2010
Pathophysiology of right ventricular failure in pulmonary hypertension
RA Bronicki, HP Baden
Pediatric Critical Care Medicine 2010
MicroRNAs are dynamically regulated in hypertrophic hearts, and miR-199a is essential for the maintenance of cell size in cardiomyocytes
XW Song, Q Li, L Lin, XC Wang, DF Li, GK Wang, AJ Ren, YR Wang, YW Qin, WJ Yuan, Q Jing
Journal of Cellular Physiology 2010
Right Ventricular Heart Failure From Pulmonary Embolism: Key Distinctions From Chronic Pulmonary Hypertension
JA Watts, MR Marchick, JA Kline
Journal of Cardiac Failure 2010
Expression of microRNA-208 is Associated With Adverse Clinical Outcomes in Human Dilated Cardiomyopathy
M Satoh, Y Minami, Y Takahashi, T Tabuchi, M Nakamura
Journal of Cardiac Failure 2010
Altered in vivo left ventricular torsion and principal strains in hypothyroid rats
Y Chen, A Somji, X Yu, JE Stelzer
American journal of physiology. Heart and circulatory physiology 2010
Reactive Oxygen/Nitrogen Species and the Myocardial Cell Homeostasis: An Ambiguous Relationship
GM Kuster, SP Häuselmann, BI Rosc-Schlüter, V Lorenz, O Pfister
Antioxidants & Redox Signaling 2010
Characteristics of Interstitial Fibrosis and Inflammatory Cell Infiltration in Right Ventricles of Systemic Sclerosis-Associated Pulmonary Arterial Hypertension
MJ Overbeek, KT Mouchaers, HM Niessen, AM Hadi, K Kupreishvili, A Boonstra, AE Voskuyl, JA Belien, EF Smit, BC Dijkmans, A Vonk-Noordegraaf, K Grünberg
International Journal of Rheumatology 2010
Altered in vivo left ventricular torsion and principal strains in hypothyroid rats
Y Chen, A Somji, X Yu, JE Stelzer
American journal of physiology. Heart and circulatory physiology 2010
Ca 2+ -independent positive molecular inotropy for failing rabbit and human cardiac muscle by α-myosin motor gene transfer
TJ Herron, E Devaney, L Mundada, E Arden, S Day, G Guerrero-Serna, I Turner, M Westfall, JM Metzger
The FASEB Journal 2010
Textbook of Pulmonary Vascular Disease
, JG Garcia, JB West, CA Hales, S Rich, SL Archer
2010
Left-Ventricular Remodeling After Myocardial Infarction Is Associated with a Cardiomyocyte-Specific Hypothyroid Condition
CJ Pol, A Muller, MJ Zuidwijk, ED van Deel, E Kaptein, A Saba, M Marchini, R Zucchi, TJ Visser, WJ Paulus, DJ Duncker, WS Simonides
Endocrinology 2010
Perspectives on novel therapeutic strategies for right heart failure in pulmonary arterial hypertension: lessons from the left heart.
Handoko ML, de Man FS, Allaart CP, Paulus WJ, Westerhof N, Vonk-Noordegraaf A
2010
A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance
E Rooij, D Quiat, BA Johnson, LB Sutherland, X Qi, JA Richardson, RJ Kelm, EN Olson
Developmental Cell 2009
The Right Ventricle Under Pressure
HJ Bogaard, K Abe, AV Noordegraaf, NF Voelkel
Chest 2009
α1-Adrenergic Receptor Subtypes in Nonfailing and Failing Human Myocardium
BC Jensen, PM Swigart, TD Marco, C Hoopes, PC Simpson
Circulation. Heart failure 2009
Determination of rate constants for turnover of myosin isoforms in rat myocardium: implications for in vivo contractile kinetics
MR Locher, MV Razumova, JE Stelzer, HS Norman, JR Patel, RL Moss
American journal of physiology. Heart and circulatory physiology 2009
Increased Phosphorylation-Dependent Nuclear Export of Class II Histone Deacetylases in Failing Human Heart
MB Calalb, TA McKinsey, S Newkirk, K Huynh, CC Sucharov, MR Bristow
Clinical and Translational Science 2009
Right ventricle in pulmonary arterial hypertension: haemodynamics, structural changes, imaging, and proposal of a study protocol aimed to assess remodelling and treatment effects
LP Badano, C Ginghina, J Easaw, D Muraru, MT Grillo, P Lancellotti, B Pinamonti, G Coghlan, MP Marra, BA Popescu, SD Vita
European Journal of Echocardiography 2009
The CAAT-binding transcription factor 1/nuclear factor 1 binding site is important in β-myosin heavy chain antisense promoter regulation in rats: Myosin heavy chain β antisense promoter regulation
JM Giger, PW Bodell, KM Baldwin, F Haddad
Experimental Physiology 2009
Determination of rate constants for turnover of myosin isoforms in rat myocardium: implications for in vivo contractile kinetics
MR Locher, MV Razumova, JE Stelzer, HS Norman, JR Patel, RL Moss
American journal of physiology. Heart and circulatory physiology 2009
Purification of cardiac myocytes from human heart biopsies for gene expression analysis
LM Kosloski, IK Bales, KB Allen, BL Walker, AM Borkon, RS Stuart, AF Pak, MJ Wacker
American journal of physiology. Heart and circulatory physiology 2009
Thyroid and Heart Failure
G Iervasi, A Pingitore
2009
Prolonged administration of a dithiol antioxidant protects against ventricular remodeling due to ischemia-reperfusion in mice
SK Ambler, YK Hodges, GM Jones, CS Long, LD Horwitz
American journal of physiology. Heart and circulatory physiology 2008
Tackling heart failure in the twenty-first century
JO Mudd, DA Kass
Nature 2008
Protein Science Encyclopedia
G Schmitz, T Langmann
Protein Science Encyclopedia 2008
Molecular regulation of cardiac hypertrophy
SP Barry, SM Davidson, PA Townsend
The International Journal of Biochemistry & Cell Biology 2008
Modulation of Cardiac Performance by Motor Protein Gene Transfer
TJ Herron, EJ Devaney, JM Metzger
Annals of the New York Academy of Sciences 2008
Reversing Advanced Heart Failure by Targeting Ca2+Cycling
DM Kaye, M Hoshijima, KR Chien
Annual Review of Medicine 2008
Induction by left ventricular overload and left ventricular failure of the human Jumonji gene (JARID2) encoding a protein that regulates transcription and reexpression of a protective fetal program
E Bovill, S Westaby, S Reji, R Sayeed, A Crisp, T Shaw
The Journal of Thoracic and Cardiovascular Surgery 2008
Reduced expression of thyroid hormone receptors and beta-adrenergic receptors in human failing cardiomyocytes
PA Modesti, M Marchetta, T Gamberi, G Lucchese, M Maccherini, M Chiavarelli, A Modesti
Biochemical Pharmacology 2008
Histone deacetylase inhibition in the treatment of heart disease
JM Berry, DJ Cao, BA Rothermel, JA Hill
Expert Opinion on Drug Safety 2008
Myocardial Gene Expression in Heart Failure Patients Treated With Cardiac Resynchronization Therapy
M Vanderheyden, W Mullens, L Delrue, M Goethals, B Bruyne, W Wijns, P Geelen, S Verstreken, F Wellens, J Bartunek
Journal of the American College of Cardiology 2008
Reversing Advanced Heart Failure by Targeting Ca 2+ Cycling
DM Kaye, M Hoshijima, KR Chien
Annual Review of Medicine 2008
Transmural variation in myosin heavy chain isoform expression modulates the timing of myocardial force generation in porcine left ventricle: Transmural mechanics in porcine myocardium
JE Stelzer, HS Norman, PP Chen, JR Patel, RL Moss
The Journal of Physiology 2008
Designing Heart Performance by Gene Transfer
J Davis, MV Westfall, D Townsend, M Blankinship, TJ Herron, G Guerrero-Serna, W Wang, E Devaney, JM Metzger
Physiological reviews 2008
Prolonged administration of a dithiol antioxidant protects against ventricular remodeling due to ischemia-reperfusion in mice
SK Ambler, YK Hodges, GM Jones, CS Long, LD Horwitz
American journal of physiology. Heart and circulatory physiology 2008
Cardiac MHC gene expression: more complexity and a step forward
JG Edwards
American journal of physiology. Heart and circulatory physiology 2008
Increased FOG-2 in Failing Myocardium Disrupts Thyroid Hormone–Dependent SERCA2 Gene Transcription
R Rouf, S Greytak, EC Wooten, J Wu, J Boltax, M Picard, EC Svensson, WH Dillmann, RD Patten, GS Huggins
Circulation research 2008
Control of Stress-Dependent Cardiac Growth and Gene Expression by a MicroRNA
E van Rooij, LB Sutherland, X Qi, JA Richardson, J Hill, EN Olson
Science 2007
Assist Devices Fail to Reverse Patterns of Fetal Gene Expression Despite β-Blockers
BD Lowes, R Zolty, SF Shakar, A Brieke, N Gray, M Reed, M Calalb, W Minobe, JA Lindenfeld, EE Wolfel, M Geraci, MR Bristow, J Cleveland
The Journal of Heart and Lung Transplantation 2007
Effect of Cardiac Resynchronization Therapy on Myocardial Gene Expression in Patients with Nonischemic Dilated Cardiomyopathy
S Iyengar, G Haas, S Lamba, DA Orsinelli, GJ Babu, AK Ferketich, L Yamokoski, M Periasamy, WT Abraham
Journal of Cardiac Failure 2007
Role of myosin heavy chain composition in the stretch activation response of rat myocardium
JE Stelzer, SL Brickson, MR Locher, RL Moss
The Journal of Physiology 2007
Changes in Sarcomeric and Non-sarcomeric Cytoskeletal Proteins and Focal Adhesion Molecules During Clinical Myocardial Recovery After Left Ventricular Assist Device Support
N Latif, MH Yacoub, R George, PJ Barton, EJ Birks
The Journal of Heart and Lung Transplantation 2007
Distribution and Structure-Function Relationship of Myosin Heavy Chain Isoforms in the Adult Mouse Heart
M Krenz, S Sadayappan, HE Osinska, JA Henry, S Beck, DM Warshaw, J Robbins
The Journal of biological chemistry 2007
Pharmacological impact on right ventricular remodelling in pulmonary arterial hypertension
N Galié, A Manes, M Palazzini, L Negro, S Romanazzi, A Branzi
European Heart Journal Supplements 2007
Cardiovascular Medicine
JT Willerson, HJ Wellens, JN Cohn, DR Holmes
2007
Thyroid Function Disturbance and Type 3 Iodothyronine Deiodinase Induction after Myocardial Infarction in Rats—A Time Course Study
EL Olivares, MP Marassi, RS Fortunato, AC da Silva, RH Costa-e-Sousa, IG Araújo, EC Mattos, MO Masuda, MA Mulcahey, SA Huang, AC Bianco, DP Carvalho
Endocrinology 2007
Intermittent Pressure Overload Triggers Hypertrophy-independent Cardiac Dysfunction and Vascular Rarefaction
Cinzia Perrino, Sathyamangla V. Naga Prasad, Lan Mao, Takahisa Noma, Zhen Yan, Hyung-Suk Kim, Oliver Smithies and Howard A. Rockman
Journal of Clinical Investigation 2006
Effects of gradual coronary artery occlusion and exercise training on gene expression in swine heart
MO Boluyt, GM Cirrincione, AM Loyd, DH Korzick, JL Parker, MH Laughlin
Molecular and Cellular Biochemistry 2006
Myofibrillar remodelling in cardiac hypertrophy, heart failure and cardiomyopathies
J Machackova, J Barta, NS Dhalla
Canadian Journal of Cardiology 2006
Proteomic analysis of membrane microdomains derived from both failing and non-failing human hearts
C Banfi, M Brioschi, R Wait, S Begum, E Gianazza, P Fratto, G Polvani, E Vitali, A Parolari, L Mussoni, E Tremoli
PROTEOMICS 2006
A polymorphism within a conserved beta(1)-adrenergic receptor motif alters cardiac function and beta-blocker response in human heart failure
SB Liggett, J Mialet-Perez, S Thaneemit-Chen, SA Weber, SM Greene, D Hodne, B Nelson, J Morrison, MJ Domanski, LE Wagoner, WT Abraham, JL Anderson, JF Carlquist, HJ Krause-Steinrauf, LC Lazzeroni, JD Port, PW Lavori, MR Bristow
Proceedings of the National Academy of Sciences 2006
Serial gene expression profiling in the intact human heart
BD Lowes, R Zolty, WA Minobe, AD Robertson, S Leach, L Hunter, MR Bristow
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2006
Myofibrillar remodeling in cardiac hypertrophy, heart failure and cardiomyopathies
J Machackova, J Barta, NS Dhalla
The Canadian journal of cardiology 2006
Novel Imaging Strategies for Predicting Remodeling and Evolution of Heart Failure: Targeting the Renin-angiotensin System
J Shirani, J Narula, WC Eckelman, V Dilsizian
Heart Failure Clinics 2006
Skeletal Muscle Plasticity in Health and Disease
R Bottinelli, C Reggiani
2006
Thyroid hormone induces cardiac myocyte hypertrophy in a thyroid hormone receptor alpha1-specific manner that requires TAK1 and p38 mitogen-activated protein kinase
K Kinugawa, MY Jeong, MR Bristow, CS Long
Molecular Endocrinology 2005
Rethinking the Renin-Angiotensin System and Its Role in Cardiovascular Regulation
P Pagliaro, C Penna
Cardiovascular Drugs and Therapy 2005
Thin Filament Remodeling in Failing Myocardium
P VanBuren, Y Okada
Heart Failure Reviews 2005
Thick Filament Proteins and Performance in Human Heart Failure
BM Palmer
Heart Failure Reviews 2005
Molecular remodeling in the failing human heart
DA Rivera, BD Lowes
Current Heart Failure Reports 2005
Myosin heavy chain composition and the economy of contraction in healthy and diseased human myocardium
NA Narolska, S Eiras, RB Loon, NM Boontje, R Zaremba, SR berg, W Stooker, MA Huybregts, FC Visser, J Velden, GJ Stienen
Journal of Muscle Research and Cell Motility 2005
Jumonji represses α-cardiac myosin heavy chain expression via inhibiting MEF2 activity
T Kim, J Jung, MR Mysliwiec, S Kang, Y Lee
Biochemical and Biophysical Research Communications 2005
Myocardial Expression of Fas and Recovery of Left Ventricular Function in Patients With Recent-Onset Cardiomyopathy
R Sheppard, M Bedi, T Kubota, MJ Semigran, W Dec, R Holubkov, AM Feldman, WD Rosenblum, CF McTiernan, DM McNamara
Journal of the American College of Cardiology 2005
Nifedipine represses ion channels, transporters and Ca(2+)-binding proteins in hearts of spontaneously hypertensive rats
C Zwadlo, J Borlak
Toxicology and Applied Pharmacology 2005
Quantitative analysis of proteomics using data mining
CY Yen, SM Helmike, KJ Cios, MB Perryman, MW Duncan
IEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society 2005
Posttranscriptional regulation of myosin heavy chain expression in the heart by triiodothyronine
S Danzi, I Klein
American journal of physiology. Heart and circulatory physiology 2005
Power output is linearly related to MyHC content in rat skinned myocytes and isolated working hearts
FS Korte, TJ Herron, MJ Rovetto, KS McDonald
American journal of physiology. Heart and circulatory physiology 2005
Ligand-mediated decrease of thyroid hormone receptor-α 1 in cardiomyocytes by proteosome-dependent degradation and altered mRNA stability
A Kenessey, K Ojamaa
American journal of physiology. Heart and circulatory physiology 2005
Gene expression analysis of ischemic and nonischemic cardiomyopathy: shared and distinct genes in the development of heart failure
MM Kittleson, KM Minhas, RA Irizarry, SQ Ye, G Edness, E Breton, JV Conte, G Tomaselli, JG Garcia, JM Hare
Physiological genomics 2005
Forced Expression of α-Myosin Heavy Chain in the Rabbit Ventricle Results in Cardioprotection Under Cardiomyopathic Conditions
J James, L Martin, M Krenz, C Quatman, F Jones, R Klevitsky, J Gulick, J Robbins
Circulation 2005
Myosin heavy chain composition and the economy of contraction in healthy and diseased human myocardium
NA Narolska, S Eiras, RB van Loon, NM Boontje, R Zaremba, SR berg, W Stooker, MA Huybregts, FC Visser, J van der Velden, GJ Stienen
Journal of Muscle Research and Cell Motility 2005
Impact of beta-myosin heavy chain expression on cardiac function during stress
M Krenz, J Robbins
Journal of the American College of Cardiology 2004
Differential gene expression in infarct scar and viable myocardium from rat heart following coronary ligation
YJ Xu, D Chapman, IM Dixon, R Sethi, X Guo, NS Dhalla
Journal of Cellular and Molecular Medicine 2004
Gene expression profiles in end-stage human idiopathic dilated cardiomyopathy: altered expression of apoptotic and cytoskeletal genes
CK Yung, VL Halperin, GF Tomaselli, RL Winslow
Genomics 2004
Novel targets of ANG II regulation in mouse heart identified by serial analysis of gene expression
F Schwartz, A Duka, I Duka, J Cui, H Gavras
American journal of physiology. Heart and circulatory physiology 2004
Pathophysiology of Cardiovascular Disease
NS Dhalla, H Rupp, A Angel, GN Pierce
2004
Simultaneous Quantification of Human Cardiac α- and β-Myosin Heavy Chain Proteins by MALDI-TOF Mass Spectrometry
SM Helmke, CY Yen, KJ Cios, K Nunley, MR Bristow, MW Duncan, MB Perryman
Analytical Chemistry 2004
The Ku Protein Complex Interacts with YY1, Is Up-Regulated in Human Heart Failure, and Represses α Myosin Heavy-Chain Gene Expression
CC Sucharov, SM Helmke, SJ Langer, MB Perryman, M Bristow, L Leinwand
Molecular and cellular biology 2004
Biologic Rationale for the Use of Beta-Blockers in the Treatment of Heart Failure
HN Sabbah
Heart Failure Reviews 2004
Role of microtubules versus myosin heavy chain isoforms in contractile dysfunction of hypertrophied murine cardiocytes
Y Ishibashi, M Takahashi, Y Isomatsu, F Qiao, Y Iijima, H Shiraishi, JM Simsic, CF Baicu, J Robbins, MR Zile, GC 4th
American journal of physiology. Heart and circulatory physiology 2003
Decreased expression of beta1- and beta2-adrenoceptors in human diabetic atrial appendage
UD Dinçer, S Güner, A Tay, E Arioğlu, A Taşdelen, S Aşlamaci, KR Bidasee
Cardiovascular Diabetology 2003
Hallmarks of ion channel gene expression in end-stage heart failure
J Borlak, T Thum
The FASEB Journal 2003
Growth hormone, acromegaly, and heart failure: an intricate triangulation
L Sacca, R Napoli, A Cittadini
Clinical Endocrinology 2003
Changes in myocardial gene expression associated with β-blocker therapy in patients with chronic heart failure
Y Yasumura, K Takemura, A Sakamoto, M Kitakaze, K Miyatake
Journal of Cardiac Failure 2003
Switching Between Beta Blockers in Heart Failure Patients: Rationale and Practical Considerations
WT Abraham
Congestive Heart Failure 2003
Pathogenetic basis of myocardial dysfunction and amenability to reversal
S Garg, J Narula
Cardiology Clinics 2003
Hypoplastic left heart syndrome myocytes are differentiated but possess a unique phenotype
TJ Bohlmeyer, S Helmke, S Ge, J Lynch, G Brodsky, JH Sederberg, AD Robertson, W Minobe, MR Bristow, MB Perryman
Cardiovascular Pathology 2003
Yin Yang 1 Is Increased in Human Heart Failure and Represses the Activity of the Human α-Myosin Heavy Chain Promoter
CC Sucharov, P Mariner, C Long, M Bristow, L Leinwand
The Journal of biological chemistry 2003
Role of Antisense RNA in Coordinating Cardiac Myosin Heavy Chain Gene Switching
F Haddad, PW Bodell, AX Qin, JM Giger, KM Baldwin
The Journal of biological chemistry 2003
Cocaine Produces Cardiac Hypertrophy by Protein Kinase C Dependent Mechanisms
RJ Henning, Y Li
Journal of cardiovascular pharmacology and therapeutics 2003
Transcriptomal analysis of failing and nonfailing human hearts
M Steenman, YW Chen, ML Cunff, G Lamirault, A Varró, E Hoffman, JJ Léger
Physiological genomics 2003
Mg-ATPase and Ca+ activated myosin AtPase activity in ventricular myofibrils from non-failing and diseased human hearts--effects of calcium sensitizing agents MCI-154, DPI 201-106, and caffeine
Chukwuka Okafor, Ronglih Liao, Cynthia Perreault-Micale, Xiaoping Li, Toshiro Ito, Anna Stepanek, Angelia Doye, Pieter de Tombe, Judith K Gwathmey
Molecular and Cellular Biochemistry 2003
Myocardin mRNA is augmented in the failing myocardium: expression profiling in the porcine model and human dilated cardiomyopathy
M Torrado, E Lpez, A Centeno, C Medrano, A Castro-Beiras, AT Mikhailov
Journal of Molecular Medicine 2003
Molecular and cellular mechanisms of myocardial remodeling
M Maytin
Journal of Nuclear Cardiology 2002
Dexrazoxane pre-treatment protects skinned rat cardiac trabeculae against delayed doxorubicin-induced impairment of crossbridge kinetics
EL de Beer, AE Bottone, MC van Rijk, J der Velden, EE Voest
British Journal of Pharmacology 2002
A molecular mechanism improving the contractile state in human myocardial hypertrophy
O Ritter, N Bottez, N Burkard, HD Schulte, L Neyses
Experimental and clinical cardiology 2002
Coordinate changes in Myosin heavy chain isoform gene expression are selectively associated with alterations in dilated cardiomyopathy phenotype
WT Abraham, EM Gilbert, BD Lowes, WA Minobe, P Larrabee, RL Roden, D Dutcher, J Sederberg, JA Lindenfeld, EE Wolfel, SF Shakar, D Ferguson, K Volkman, JV Linseman, RA Quaife, AD Robertson, MR Bristow
Molecular Medicine 2002
Quantitative Analysis of the Expression and Distribution of Calcium Channel α 1 Subunit mRNA in the Atria and Ventricles of the Rat Heart
JK Larsen, JW Mitchell, PM Best
Journal of Molecular and Cellular Cardiology 2002
Activation and release of degradative proteinases within the myocardium are the trigger for ventricular remodeling in chronic heart failure
JD Sackner-Bernstein
Medical Hypotheses 2002
Calcium Cycling in Congestive Heart Failure
G Hasenfuss, B Pieske
Journal of Molecular and Cellular Cardiology 2002
ACE Inhibition Improves Cardiac Force Generation after Myocardial Infarction
D Hilfiker-Kleiner, H Drexler
Journal of Molecular and Cellular Cardiology 2002
PCBs alter gene expression of nuclear transcription factors and other heart-specific genes in cultures of primary cardiomyocytes: possible implications for cardiotoxicity
J Borlak, T Thum
Xenobiotica 2002
Myocardial function in rat genetic models of low and high aerobic running capacity
JC Barbato, SJ Lee, LG Koch, GT Cicila
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology 2002
Inhibition of Calcineurin and Sarcolemmal Ca 2+ Influx Protects Cardiac Morphology and Ventricular Function in K v 4.2N Transgenic Mice
R Sah, GY Oudit, TT Nguyen, HW Lim, AD Wickenden, GJ Wilson, JD Molkentin, PH Backx
Circulation 2002
Mechanics and Energetics of the Myocardium
CJ Holubarsch
2002
Signaling pathways responsible for fetal gene induction in the failing human heart: evidence for altered thyroid hormone receptor gene expression
K Kinugawa, WA Minobe, WM Wood, EC Ridgway, JD Baxter, RC Ribeiro, MF Tawadrous, BA Lowes, CS Long, MR Bristow
Circulation 2001
Microsatellite instability of endothelial cell growth and apoptosis genes within plexiform lesions in primary pulmonary hypertension
ME Yeager, GR Halley, HA Golpon, NF Voelkel, RM Tuder
Circulation research 2001
Doxorubicin and mechanical performance of cardiac trabeculae after acute and chronic treatment: a review
EL de Beer, AE Bottone, EE Voest
European Journal of Pharmacology 2001
Pathophysiology of chronic heart failure
GS Francis
The American Journal of Medicine 2001
Altered Beta-adrenergic Receptor Gene Regulation and Signaling in Chronic Heart Failure
JD Port, MR Bristow
Journal of Molecular and Cellular Cardiology 2001
THE DILEMMA OF LATE-STAGE HEART FAILURE
MR Mehra, PA Uber
Cardiology Clinics 2001
Left Ventricular Remodeling and Functional Mitral Regurgitation: Mechanisms and Therapy
AW Stanley, CL Athanasuleas, GD Buckberg
Seminars in Thoracic and Cardiovascular Surgery 2001
Human cardiac myosin heavy chain isoforms in fetal and failing adult atria and ventricles
PJ Reiser, MA Portman, XH Ning, CS Moravec
American journal of physiology. Heart and circulatory physiology 2001
Cardiac-directed overexpression of wild-type α 1B -adrenergic receptor induces dilated cardiomyopathy
I Lemire, A Ducharme, JC Tardif, F Poulin, LR Jones, BG Allen, TE Hébert, H Rindt
American journal of physiology. Heart and circulatory physiology 2001
REPROGRAMMING OF GENE EXPRESSION IN CULTURED CARDIOMYOCYTES AND IN EXPLANTED HEARTS BY THE MYOSIN ATPASE INHIBITOR BUTANEDIONE MONOXIME:
T Thum, J Borlak
Transplantation 2001
Upregulation of β 3 -Adrenoceptors and Altered Contractile Response to Inotropic Amines in Human Failing Myocardium
S Moniotte, L Kobzik, O Feron, JN Trochu, C Gauthier, JL Balligand
Circulation 2001
Independent Regulation of Cardiac Kv4.3 Potassium Channel Expression by Angiotensin II and Phenylephrine
TT Zhang, K Takimoto, AF Stewart, C Zhu, ES Levitan
Circulation research 2001
Editorial: Thyroid Hormone—Targeting the Heart
I Klein, K Ojamaa
Endocrinology 2001
Increased Expression of Thyroid Hormone Receptor Isoforms in End-Stage Human Congestive Heart Failure1
G dAmati, CR di Gioia, D Mentuccia, D Pistilli, L Proietti-Pannunzi, F Miraldi, P Gallo, FS Celi
The Journal of clinical endocrinology and metabolism 2001
Authors’ Response: Expression of TR Isoforms in Failing Human Heart
G dAmati, FS Celi
The Journal of clinical endocrinology and metabolism 2001
Evolution and Pathophysiology of Chronic Systolic Heart Failure
BE Bleske
Pharmacotherapy 2000
The role of tumor necrosis factor alpha in the pathophysiology of congestive heart failure
CF McTiernan, AM Feldman
Current Cardiology Reports 2000
Control of cardiac myosin heavy chain gene expression
E Morkin
Microscopy Research and Technique 2000
Functional implications of tissue factor localization to cell-cell contacts in myocardium
T Luther, DD Dittert, M Kotzsch, J Erlich, S Albrecht, N Mackman, M M�ller
The Journal of Pathology 2000
Modulation of in vivo cardiac hypertrophy with insulin-like growth factor-1 and angiotensin-converting enzyme inhibitor: relationship between change in myosin isoform and progression of left ventricular dysfunction
Y Iwanaga, Y Kihara, T Yoneda, T Aoyama, S Sasayama
Journal of the American College of Cardiology 2000
Remodeling the Cardiac Sarcomere Using Transgenesis
J Robbins
Annual Review of Physiology 2000
Myocyte contractile dysfunction with hypertrophy and failure: Relevance to cardiac surgery
CA Walker, FA Crawford, FG Spinale
The Journal of Thoracic and Cardiovascular Surgery 2000
Expression of proinflammatory cytokines in the failing human heart: comparison of recent-onset and end-stage congestive heart failure
T Kubota, M Miyagishima, RJ Alvarez, R Kormos, WD Rosenblum, AJ Demetris, MJ Semigran, GW Dec, R Holubkov, CF McTiernan, DL Mann, AM Feldman, DM McNamara
The Journal of Heart and Lung Transplantation 2000
Myosin heavy chain isoform expression in the failing and nonfailing human heart
Y Zou, H Akazawa, Y Qin, M Sano, H Takano, T Minamino, N Makita, K Iwanaga, W Zhu, S Kudoh, H Toko, K Tamura, M Kihara, T Nagai, A Fukamizu, S Umemura, T Iiri, T Fujita, I Komuro
Circulation research 2000
Myosin heavy chain isoform expression in the failing and nonfailing human heart
Y Zou, H Akazawa, Y Qin, M Sano, H Takano, T Minamino, N Makita, K Iwanaga, W Zhu, S Kudoh, H Toko, K Tamura, M Kihara, T Nagai, A Fukamizu, S Umemura, T Iiri, T Fujita, I Komuro
Circulation research 2000
Cellular Events Linked to Cardiac Remodeling in Heart Failure: Targets for Pharmacologic Intervention:
MR Piano, SD Kim, C Jarvis
The Journal of cardiovascular nursing 2000
Left ventricular remodelling and dysfunction
R Willenheimer
International Journal of Cardiology 2000
Alterations in Cardiac Function and Gene Expression during Autoimmune Myocarditis in Mice
LB Stull, NA DiIulio, M Yu, CF McTiernan, NB Ratliff, VK Tuohy, CS Moravec
Journal of Molecular and Cellular Cardiology 2000
Isolation and cultivation of Ca 2+ tolerant cardiomyocytes from the adult rat: improvements and applications
T Thum, J Borlak
Xenobiotica 2000
The Natriuretic Peptides: Physiology and Role in Left-Ventricular Dysfunction
SD Kim, MR Piano
Biological research for nursing 2000
Identification of the Functional Domain in the Transcription Factor RTEF-1 That Mediates α 1 -Adrenergic Signaling in Hypertrophied Cardiac Myocytes
T Ueyama, C Zhu, YM Valenzuela, JG Suzow, AF Stewart
The Journal of biological chemistry 2000
Expression of the β (slow)-isoform of MHC in the adult mouse heart causes dominant-negative functional effects
JC Tardiff, TE Hewett, SM Factor, KL Vikstrom, J Robbins, LA Leinwand
American journal of physiology. Heart and circulatory physiology 2000
Measurement of the Renin-Angiotensin System in Heart Failure
SD Kim
Biological research for nursing 2000
Cocaine Increases β-Myosin Heavy-Chain Protein Expression in Cardiac Myocytes
RJ Henning, J Silva, V Reddy, S Kamat, MB Morgan, YX Li, S Chiou
Journal of cardiovascular pharmacology and therapeutics 2000
Thyroid hormone metabolism and cardiac gene expression after acute myocardial infarction in the rat
K Ojamaa, A Kenessey, R Shenoy, I Klein
American journal of physiology. Endocrinology and metabolism 2000
Altered Inotropic Responsiveness and Gene Expression of Hypertrophied Myocardium With Captopril
WW Brooks, OH Bing, MO Boluyt, A Malhotra, JP Morgan, N Satoh, WS Colucci, CH Conrad
Hypertension 2000
β 2 -Adrenergic Receptor Overexpression Exacerbates Development of Heart Failure After Aortic Stenosis
XJ Du, DJ Autelitano, RJ Dilley, B Wang, AM Dart, EA Woodcock
Circulation 2000
Decreased SLIM1 Expression and Increased Gelsolin Expression in Failing Human Hearts Measured by High-Density Oligonucleotide Arrays
J Yang, CS Moravec, MA Sussman, NR DiPaola, D Fu, L Hawthorn, CA Mitchell, JB Young, GS Francis, PM McCarthy, M Bond
Circulation 2000
The Hypertrophied Heart
N Takeda, M Nagano, NS Dhalla
2000
Molecular Approaches to Heart Failure Therapy
G Hasenfuss, E Marbán
2000
Surgical Remodeling in Heart Failure
W Brett, A Todorov, M Pfisterer, HR Zerkowski
2000
Catecholamines and angiotensinogen gene expression in kidney proximal tubular cells
J S Chan, T T Wang, S L Zhang, X Chen, S Carrière
Molecular and Cellular Biochemistry 2000
Control of cardiomyocyte gene expression as drug target
H Rupp, M Benkel, B Maisch
Molecular and Cellular Biochemistry 2000
The cytoskeleton and related proteins in the human failing heart
S Kostin, S Hein, E Arnon, D Scholz, J Schaper
Heart Failure Reviews 2000
Dexamethasone induced cardiac hypertrophy in newborn rats is accompanied by changes in myosin heavy chain phenotype and gene transcription
S Muangmingsuk, P Ingram, M P Gupta, R A Arcilla, M Gupta
Molecular and Cellular Biochemistry 2000
A transgenic rabbit model for human hypertrophic cardiomyopathy
AJ Marian, Y Wu, DS Lim, M McCluggage, K Youker, QT Yu, R Brugada, F DeMayo, M Quinones, R Roberts
Journal of Clinical Investigation 1999
Right ventricular phenotypic characteristics in subjects with primary pulmonary hypertension or idiopathic dilated cardiomyopathy
RA Quaife, D Lynch, DB Badesch, NF Voelkel, BD Lowes, AD Robertson, MR Bristow
Journal of Cardiac Failure 1999
β-Blocker withdrawal: The song of Orpheus
EJ Eichhorn
American Heart Journal 1999
Insulin-like growth factor-1 attenuates the detrimental impact of nonocclusive coronary artery constriction on the heart
B Li, M Setoguchi, X Wang, AM Andreoli, A Leri, A Malhotra, J Kajstura, P Anversa
Circulation research 1999
Kinetic differences at the single molecule level account for the functional diversity of rabbit cardiac myosin isoforms
KA Palmiter, MJ Tyska, DE Dupuis, NR Alpert, DM Warshaw
The Journal of Physiology 1999
Adaptation to hypoxia alters energy metabolism in rat heart
WL Rumsey, B Abbott, D Bertelsen, M Mallamaci, K Hagan, D Nelson, M Erecinska
American journal of physiology. Heart and circulatory physiology 1999
Mechanisms and Models in Heart Failure: A Combinatorial Approach
DL Mann
Circulation 1999
Molecular Cardiology in Clinical Practice
M Sanders, JB Kostis
1999
The negative inotropic effect of beta3-adrenoceptor stimulation is mediated by activation of a nitric oxide synthase pathway in human ventricle
C Gauthier, V Leblais, L Kobzik, JN Trochu, N Khandoudi, A Bril, JL Balligand, HL Marec
Journal of Clinical Investigation 1998
Functional significance of cardiac myosin essential light chain isoform switching in transgenic mice
JG Fewell, TE Hewett, A Sanbe, R Klevitsky, E Hayes, D Warshaw, D Maughan, J Robbins
Journal of Clinical Investigation 1998
Cardiac remodeling as a consequence and cause of progressive heart failure
K Kurrelmeyer, D Kalra, B Bozkurt, F Wang, Z Dibbs, Y Seta, G Baumgarten, D Engle, N Sivasubramanian, DL Mann
Clinical Cardiology 1998
Treating relentlessly progressive congestive heart failure: what next?
JT Willerson, RD 3rd, D Mann
Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital 1998
Noblesse oblige
GS Francis
Journal of Cardiac Failure 1998
β-Blockade and amiodarone therapy: Twin brothers from different parents
EJ Eichhorn, MH Hamdan
Journal of Cardiac Failure 1998
Cardiomyocytes and non-muscle cells in cardiac hypertrophy: a molecular perspective
M Gupta, MP Gupta, RA Arcilla, R Zak
Progress in Pediatric Cardiology 1998
MEDICAL THERAPY OF CHRONIC HEART FAILURE
EJ Eichhorn
Cardiology Clinics 1998
2 Growth hormone: a new therapy for heart failure?
L Saccà
Baillière's Clinical Endocrinology and Metabolism 1998
The Pressure-Overloaded Right Ventricle in Pulmonary Hypertension
MR Bristow, LS Zisman, BD Lowes, WT Abraham, DB Badesch, BM Groves, NF Voelkel, DM Lynch, RA Quaife
Chest 1998
Alterations of cross-bridge kinetics in human atrial and ventricular myocardium
T Ruf, H Schulte-Baukloh, J Lüdemann, H Posival, F Beyersdorf, H Just, C Holubarsch
Cardiovascular Research 1998
Load-Dependent Myocyte Dysfunction
WH Barry
Circulation 1998
Mechanism of Action of Beta-Blocking Agents in Heart Failure
MR PhD
The American Journal of Cardiology 1997
Herzkrankheiten
H Roskamm, H Reindell
1996
In vivo assessment of LV mass in mice using high-frequency cardiac ultrasound: necropsy validation
C Depre, GL Shipley, W Chen, Q Han, T Doenst, ML Moore, S Stepkowski, PJ Davies, H Taegtmeyer
The American journal of physiology 1994
In vivo assessment of LV mass in mice using high-frequency cardiac ultrasound: necropsy validation
C Depre, GL Shipley, W Chen, Q Han, T Doenst, ML Moore, S Stepkowski, PJ Davies, H Taegtmeyer
The American journal of physiology 1994

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Referenced in 8 patents
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