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A pharmacogenetic approach to blood pressure in Lyon hypertensive rats. A chromosome 2 locus influences the response to a calcium antagonist.

M Vincent, … , G M Lathrop, J Sassard

M Vincent, … , G M Lathrop, J Sassard

Published October 15, 1997
Citation Information: J Clin Invest. 1997;100(8):2000-2006. https://doi.org/10.1172/JCI119731.

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Citations to this article (30)

Title and authors	Publication	Year
Body Composition and Metabolic Changes in a Lyon Hypertensive Congenic Rat and Identification of Ercc6l2 as a Positional Candidate Gene. Clark KC, Wagner VA, Holl KL, Reho JJ, Tutaj M, Smith JR, Dwinell MR, Grobe JL, Kwitek AE	Frontiers in Genetics	2022
Editorial: Multi-Omics Study in Revealing Underlying Pathogenesis of Complex Diseases: A Translational Perspective YM Zhang, YF Wang, H Rasheed, J Ott	Frontiers in Genetics	2021
Towards Precision Medicine for Hypertension: A Review of Genomic, Epigenomic, and Microbiomic Effects on Blood Pressure in Experimental Rat Models and Humans S Padmanabhan, B Joe	Physiological reviews	2017
Influence of autoantibodies against AT1 receptor and AGTR1 polymorphisms on candesartan-based antihypertensive regimen Y Sun, Y Liao, Y Yuan, L Feng, S Ma, F Wei, M Wang, F Zhu	Journal of the American Society of Hypertension	2014
Y27632, a Rho-activated kinase inhibitor, normalizes dysregulation in alpha1-adrenergic receptor-induced contraction of Lyon hypertensive rat artery smooth muscle MR Freitas, M Eto, JA Kirkbride, C Schott, J Sassard, JC Stoclet	Fundamental & Clinical Pharmacology	2009
Principles of Molecular Medicine MS Runge, C Patterson		2006
A quantitative trait locus for aortic smooth muscle cell number acting independently of blood pressure: implicating the angiotensin receptor AT1B gene as a candidate J Dutil, V Eliopoulos, ÉL Marchand, AM Devlin, J Tremblay, K Prithiviraj, P Hamet, A Migneault, D deBlois, AY Deng	Physiological genomics	2005
Severe hypertension caused by alleles from normotensive Lewis for a quantitative trait locus on chromosome 2 V Eliopoulos, J Dutil, Y Deng, M Grondin, AY Deng	Physiological genomics	2005
Pharmacogenomics in Cardiovascular Medicine JF Carlquist, JL Anderson	Drug Development Research	2004
Pharmacogenetics of Antihypertensive Drug Responses: GL Schwartz, ST Turner	American Journal of PharmacoGenomics	2004
Genetics of blood pressure, hypertensive complications, and antihypertensive drug responses ST Turner, E Boerwinkle	Pharmacogenomics	2003
Optimal blood pressure control and antihypertensive regimens in hypertensive renal disease: the potential of exploring the mechanisms of response variability MJ Kocks, D Zeeuw, GJ Navis	Current Opinion in Nephrology and Hypertension	2002
Reciprocal rat chromosome 2 congenic strains reveal contrasting blood pressure and heart rate QTL A Alemayehu, L Breen, D Krenova, MP Printz	Physiological genomics	2002
Rat genetics: attachign physiology and pharmacology to the genome HJ Jacob, AE Kwitek	Nature Reviews Genetics	2002
Antihypertensive pharmacogenetics: getting the right drug into the right patient ST Turner, GL Schwartz, AB Chapman, WD Hall, E Boerwinkle	Journal of Hypertension	2001
Use of gene markers to guide antihypertensive therapy ST Turner, GL Schwartz, AB Chapman, E Boerwinkle	Current Hypertension Reports	2001
Further chromosomal mapping of a blood pressure QTL in Dahl rats on chromosome 2 using congenic strains J Dutil, AY Deng	Physiological genomics	2001
Altered Na + -K + pump activity and plasma lipids in salt-hypertensive Dahl rats: relationship to Atp1a1 gene J Zicha, CD Negrin, Z Dobešová, F Carr, M Vokurková, MA McBRIDE, J Kuneš, AF Dominiczak	Physiological genomics	2001
Genetic Analysis of Inherited Hypertension in the Rat JP Rapp	Physiological reviews	2000
Pharmacogenetics: Promise and Potential in Child and Adolescent Psychiatry GM Anderson, EH Cook	Child and Adolescent Psychiatric Clinics of North America	2000
Genetics of Hypertension, Target-Organ Complications, and Response to Therapy ST Turner, E Boerwinkle	Circulation	2000
The Genomics of Cardiovascular Disorders: Therapeutic Implications P Ferrari, G Bianchi	Drugs	2000
Gene-environment interactions in hypertension Z Pausova, J Tremblay, P Hamet	Current Hypertension Reports	1999
Use of animal models to search for candidate genes associated with essential hypertension M Knoblauch, K Lindpaintner	Current Hypertension Reports	1999
Genes and Hypertension: Where we are and where we Should Go P Hamet	Clinical and Experimental Hypertension	1999
Genetic and biochemical determinants of abnormal monovalent ion transport in primary hypertension SN Orlov, NC Adragna, VA Adarichev, P Hamet	American journal of physiology. Cell physiology	1999
Genomics and Hypertension: Concepts, Potentials, and Opportunities RE Pratt, VJ Dzau	Hypertension	1999
In search of hypertension genes in Dahl salt-sensitive rats AY Deng	Journal of Hypertension	1998
Genetics of experimental hypertension AF Dominiczak, JS Clark, B Jeffs, NH Anderson, CD Negrin, WK Lee, MJ Brosnan	Journal of Hypertension	1998
Pharmacogenomics P Ferrari	Current Opinion in Nephrology and Hypertension	1998

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