Research Article
M C Colbert, D G Hall, T R Kimball, S A Witt, J N Lorenz, M L Kirby, T E Hewett, R Klevitsky, J Robbins
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Gene expression profiling of dilated cardiomyopathy in older male EP4 knockout mice
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Lipids in the heart: a source of fuel and a source of toxins
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European Journal of Pharmacology | 2006 |
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Retinoic Acid Supplementation Attenuates Ventricular Remodeling after Myocardial Infarction in Rats
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The Journal of nutrition | 2005 |
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European Journal of Biochemistry | 2002 |
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American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2002 |
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RXRα overexpression in cardiomyocytes causes dilated cardiomyopathy but fails to rescue myocardial hypoplasia in RXRα-null fetuses
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Pediatric Research | 2000 |
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Functional consequences of altering myocardial adrenergic receptor signaling
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Annual Review of Physiology | 2000 |
Ventricular Expression of tbx5 Inhibits Normal Heart Chamber Development
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Y Wu, O Cazorla, D Labeit, S Labeit, H Granzier |
Journal of Molecular and Cellular Cardiology | 2000 |
Cardiac-specific overexpression of RhoA results in sinus and atrioventricular nodal dysfunction and contractile failure
VP Sah, S Minamisawa, SP Tam, TH Wu, GW 2nd, J Ross, KR Chien, JH Brown |
Journal of Clinical Investigation | 1999 |
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K Asai, GP Yang, YJ Geng, G Takagi, S Bishop, Y Ishikawa, RP Shannon, TE Wagner, DE Vatner, CJ Homcy, SF Vatner |
Journal of Clinical Investigation | 1999 |
Pathogenesis of Dilated Cardiomyopathy
MA Sussman, S Welch, N Gude, PR Khoury, SR Daniels, D Kirkpatrick, RA Walsh, RL Price, HW Lim, JD Molkentin |
The American Journal of Pathology | 1999 |
Retinoids and cell growth in the cardiovascular system
DG Gardner, S Chen |
Life Sciences | 1999 |
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GW 2nd, MC Souroujon, T Liron, CH Chen, MO Gray, HZ Zhou, M Csukai, G Wu, JN Lorenz, D Mochly-Rosen |
Proceedings of the National Academy of Sciences | 1999 |
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Current Opinion in Genetics & Development | 1999 |
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GW Dorn, MC Souroujon, T Liron, CH Chen, MO Gray, HZ Zhou, M Csukai, G Wu, JN Lorenz, D Mochly-Rosen |
Proceedings of the National Academy of Sciences | 1999 |
Abnormal Cardiac Structure and Function in Mice Expressing Nonphosphorylatable Cardiac Regulatory Myosin Light Chain 2
A Sanbe, JG Fewell, J Gulick, H Osinska, J Lorenz, DG Hall, LA Murray, TR Kimball, SA Witt, J Robbins |
The Journal of biological chemistry | 1999 |
Combinatorial Interactions Regulate Cardiac Expression of the Murine Adenylosuccinate Synthetase 1 Gene
AL Lewis, Y Xia, SK Datta, J McMillin, RE Kellems |
The Journal of biological chemistry | 1999 |
A novel heart failure model induced by sequential coronary artery occlusions and tachycardiac stress in awake pigs
YT Shen, JJ Lynch, RP Shannon, RT Wiedmann |
American journal of physiology. Heart and circulatory physiology | 1999 |
Functional significance of cardiac myosin essential light chain isoform switching in transgenic mice
JG Fewell, TE Hewett, A Sanbe, R Klevitsky, E Hayes, D Warshaw, D Maughan, J Robbins |
Journal of Clinical Investigation | 1998 |
Retinoic acid uses divergent mechanisms to activate or suppress mitogenesis in rat aortic smooth muscle cells
S Chen, DG Gardner |
Journal of Clinical Investigation | 1998 |
Genetically engineered mice: Model systems for left ventricular failure
VJ Kadambi, EG Kranias |
Journal of Cardiac Failure | 1998 |
Cardiac transgenic and gene-targeted mice as models of cardiac hypertrophy and failure: A problem of (new) riches
S Izumo, T Shioi |
Journal of Cardiac Failure | 1998 |
Reversal of Hypocalcemia and Decreased Afterload in Sepsis: Effect on Myocardial Systolic and Diastolic Function
A Kovacs, MR Courtois, B Barzilai, IE Karl, PA Ludbrook, RS Hotchkiss |
American journal of respiratory and critical care medicine | 1998 |
Molecular regulation of cardiac myogenesis and morphology during development
M Gupta, MP Gupta, RA Arcilla |
Progress in Pediatric Cardiology | 1998 |
The diverse roles of neural crest in cardiovascular development: myocardial function, aortic arch repatterning and outflow septation
ML Kirby, M Farrell |
Progress in Pediatric Cardiology | 1998 |
Cardiac Physiology in Transgenic Mice
JF James, TE Hewett, J Robbins |
Circulation research | 1998 |
Timing Is Everything in Life: Conditional Transgene Expression in the Cardiovascular System
GI Fishman |
Circulation research | 1998 |
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
WR MacLellan, MD Schneider |
Cell | 1993 |
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
WR MacLellan, MD Schneider |
Cell | 1993 |
The mechanism of action of cyclosporin A and FK506
T Meguro, C Hong, K Asai, G Takagi, TA McKinsey, EN Olson, SF Vatner |
Immunology Today | 1992 |