Research Article
T D Batiuk, L Kung, P F Halloran
Title and authors | Publication | Year |
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Sustained Inhibition of Calcineurin Activity With a Melt‐Dose Once‐daily Tacrolimus Formulation in Renal Transplant Recipients
P Fontova, H Colom, R RigoBonnin, O Bestard, A VidalAlabró, LN van Merendonk, G Cerezo, C Polo, N Montero, E Melilli, A Manonelles, M Meneghini, A Coloma, JM Cruzado, J Torras, JM Grinyó, N Lloberas |
Clinical Pharmacology & Therapeutics | 2021 |
Activation of the vitamin D receptor selectively interferes with calcineurin-mediated inflammation: a clinical evaluation in the abdominal aortic aneurysm
AJ Nieuwland, VB Kokje, OH Koning, JF Hamming, K Szuhai, FH Claas, JH Lindeman |
Laboratory Investigation | 2016 |
Quantifying MHC dextramer-induced NFAT activation in antigen-specific T cells as a functional response parameter
O Maguire, GL Chen, TE Hahn, L Brix, PL McCarthy, PK Wallace, H Minderman |
Methods | 2016 |
Pediatric Kidney Disease
DF Geary, F Schaefer |
Pediatric Kidney Disease | 2016 |
Update on pathogenesis and predictors of response of therapeutic strategies used in inflammatory bowel disease
EG Quetglas |
World journal of gastroenterology : WJG | 2015 |
Nuclear translocation of nuclear factor of activated T cells (NFAT) as a quantitative pharmacodynamic parameter for tacrolimus
O Maguire, KM Tornatore, KL O'Loughlin, RC Venuto, H Minderman |
Cytometry Part A | 2013 |
Expression of Calcineurin Activity after Lung Transplantation: A 2-Year Follow-Up
S Sanquer, C Amrein, D Grenet, R Guillemain, B Philippe, V Boussaud, L Herry, C Lena, A Diouf, M Paunet, EM Billaud, F Loriaux, JP Jais, R Barouki, M Stern, A Gregson |
PloS one | 2013 |
Toward managing chronic rejection after lung transplant: The fate and effects of inhaled cyclosporine in a complex environment
RW Niven |
Advanced Drug Delivery Reviews | 2011 |
Pharmacodynamic Monitoring of Canine T-Cell Cytokine Responses to Oral Cyclosporine
TM Archer, CL Fellman, JV Stokes, LM Pinchuk, KV Lunsford, SB Pruett, VC Langston, AJ Mackin |
Journal of Veterinary Internal Medicine | 2011 |
Biomarkers
F Dieterle, FD Sistare |
Biomarkers | 2010 |
Effects of Ultraviolet A-1 Radiation on Calcineurin Activity and Cytokine Production in (Skin) Cell Cultures
N Smit, R Musson, F Romijn, H Rossum, J Pelt |
Photochemistry and Photobiology | 2010 |
Immunopotentiation on murine spleen lymphocytes induced by polysaccharide fraction ofPanax ginsengvia upregulating calcineurin activity
SD Zhang, YX Yin, Q Wei |
APMIS | 2010 |
Whole blood flow cytometric measurement of NFATc1 and IL-2 expression to analyze cyclosporine A-mediated effects in T cells
C Brandt, P Liman, H Bendfeldt, K Mueller, P Reinke, A Radbruch, M Worm, R Baumgrass |
Cytometry Part A | 2010 |
T-cell receptor-stimulated calcineurin activity is inhibited in isolated T cells from transplant patients
JA Tumlin, BR Roberts, KE Kokko, OE Minshawy, JL Gooch |
The Journal of pharmacology and experimental therapeutics | 2009 |
Renoprotective immunosuppression by pioglitazone with low-dose cyclosporine in rat heart transplantation
Y Tanaka, T Hasegawa, Z Chen, Y Okita, K Okada |
The Journal of Thoracic and Cardiovascular Surgery | 2009 |
Pharmacodynamic Monitoring of Calcineurin Phosphatase Activity in Transplant Patients Treated with Calcineurin Inhibitors
I YANO |
Drug Metabolism and Pharmacokinetics | 2008 |
Immunological Monitoring of Calcineurin Inhibitors for Predicting Cytomegalovirus Infection in Kidney Transplant Recipients
L Couzi, R Thiébaut, JC Carron, JF Moreau, P Merville, JL Taupin |
Transplantation | 2008 |
Comprehensive Pediatric Nephrology
R Gbadegesin, WE Smoyer |
Comprehensive Pediatric Nephrology | 2008 |
Variation in Leukocyte Subset Concentrations Affects Calcineurin Activity Measurement: Implications for Pharmacodynamic Monitoring Strategies
HH van Rossum, FP Romijn, KJ Sellar, NP Smit, PJ van der Boog, JW de Fijter, J van Pelt |
Clinical chemistry | 2008 |
Use of mTOR inhibitors in human organ transplantation
AS MacDonald |
Expert Review of Clinical Immunology | 2007 |
Increased Levels of NF-ATc2 Differentially Regulate CD154 and IL-2 Genes in T Cells from Patients with Systemic Lupus Erythematosus
VC Kyttaris, Y Wang, YT Juang, A Weinstein, GC Tsokos |
Journal of immunology (Baltimore, Md. : 1950) | 2007 |
Spectrophotometric assay for calcineurin activity in leukocytes isolated from human blood
KJ Sellar, HH van Rossum, FP Romijn, NP Smit, JW de Fijter, J Pelt |
Analytical Biochemistry | 2006 |
Suitable Whole Blood Levels 2 Hours After Neoral in Liver Transplant Patients: Experiences at a Single Center
KH Kim, SG Lee, YJ Lee, KM Park, S Hwang, CS Ahn, DB Moon, TY Ha, KW Song, DS Kim, DH Jung, BS Kim, KM Moon, HJ Lee, JI Park, JH Ryu |
Transplantation Proceedings | 2006 |
Localisation of High Acid Phosphotyrosine Phosphatase Activity in Afferent Arterioles and Glomeruli of Human Kidney
S Partanen |
Journal Of Molecular Histology | 2005 |
Cyclosporine Monitoring With 2-Hour Postdose Levels in Heart Transplant Recipients
SG Solari, LR Goldberg, D DeNofrio, LM Shaw |
Therapeutic Drug Monitoring | 2005 |
Inositol trisphosphate receptor calcium release is required for cerebral artery smooth muscle cell proliferation
MK Wilkerson |
American journal of physiology. Heart and circulatory physiology | 2005 |
Inhibition of the Calcineurin-NFAT Interaction by Small Organic Molecules Reflects Binding at an Allosteric Site
S Kang, H Li, A Rao, PG Hogan |
The Journal of biological chemistry | 2005 |
Barbiturates directly inhibit the calmodulin/calcineurin complex: a novel mechanism of inhibition of nuclear factor of activated T cells
M Humar, SE Pischke, T Loop, A Hoetzel, R Schmidt, C Klaas, HL Pahl, KK Geiger, BH Pannen |
Molecular pharmacology | 2004 |
DEFECTIVE INHIBITION OF PERIPHERAL CD8+ T CELL IL-2 PRODUCTION BY ANTI-CALCINEURIN DRUGS DURING ACUTE LIVER ALLOGRAFT REJECTION
E Boleslawski, F Conti, S Sanquer, P Podevin, S Chouzenoux, F Batteux, D Houssin, B Weill, Y Calmus |
Transplantation | 2004 |
Neoral C2 monitoring in maintenance liver transplant patients: A step forward?
GA Levy, EH Cole |
Liver Transplantation | 2004 |
Cyclosporin exposure correlates with 1 year graft function and histological damage in renal transplanted patients
S Paolo, A Teutonico, G Stallone, B Infante, A Schena, G Grandaliano, M Battaglia, P Ditonno, PF Schena |
Nephrology Dialysis Transplantation | 2004 |
Neoral C2 monitoring in solid organ transplantation
GA Levy |
Transplantation Proceedings | 2004 |
Pharmacology of calcineurin antagonists
MH Kapturczak, HU Meier-Kriesche, B Kaplan |
Transplantation Proceedings | 2004 |
Calcineurin activity as a functional index of immunosuppression after allogeneic stem-cell transplantation1:
S Sanquer, M Schwarzinger, S Maury, K Yakouben, H Rafi, C Pautas, M Kuentz, R Barouki, C Cordonnier |
Transplantation | 2004 |
Distinct Inhibitory Effects of Tacrolimus and Cyclosporin A on Calcineurin Phosphatase Activity
M Fukudo, I Yano, S Masuda, M Okuda, K Inui |
The Journal of pharmacology and experimental therapeutics | 2004 |
Circulating levels of cyclosporin A in inflammatory bowel disease: relationships with lymphocyte inhibition and the age of patients
G Angeloni, M Latteri, R Manna, C Rumi, G Gasbarrini, P Navarra |
European Journal of Clinical Pharmacology | 2004 |
Failure of cyclosporin A to induce transforming growth factor beta (TGF-beta) synthesis in activated peripheral blood lymphocytes
M Goppelt-Struebe, B Esslinger, U Kunzendorf |
Clinical Transplantation | 2003 |
Atypical mechanisms regulate the PMA-induced expression of IFN-γ in a porcine trophectoderm cell line
P Marcelo, M Bernoin, F Lefèvre |
Veterinary Immunology and Immunopathology | 2003 |
Cyclosporine lymphocyte level and lymphocyte count: new guidelines for tailoring immunosuppressive therapy
A Barbari, A Stephan, M Masri, N Mourad, G Kamel, H Kilani, A Karam, IA Daya |
Transplantation Proceedings | 2003 |
Substitution in Position 3 of Cyclosporin A Abolishes the Cyclophilin-mediated Gain-of-function Mechanism but Not Immunosuppression
R Baumgrass, Y Zhang, F Erdmann, A Thiel, M Weiwad, A Radbruch, G Fischer |
The Journal of biological chemistry | 2003 |
New developments in immunosuppressive therapy in renal transplantation
S Gourishankar, P Turner, P Halloran |
Expert Opinion on Biological Therapy | 2002 |
Two-hour post-dose cyclosporine level is a better predictor than trough level of acute rejection of renal allografts
MD Pescovitz, R Barbeito |
Clinical Transplantation | 2002 |
Tissue Distribution of Calcineurin and its Sensitivity to Inhibition by Cyclosporine
L Kung, TD Batiuk, S Palomo-Pinon, J Noujaim, LM Helms, PF Halloran |
American Journal of Transplantation | 2001 |
Controlling duration of contact between T cells and antigen-presenting cells
S Kim, NS Braunstein, EF Leonard, JL Thomas |
Journal of Immunological Methods | 2001 |
Functional quantification of cyclosporine A and FK506 in human whole blood by flow cytometry, using the green fluorescent protein as an interleukin-2 reporter gene
JL Taupin, P Merville, T McBride, L Potaux, JF Moreau |
Journal of Immunological Methods | 2001 |
Mechanism of action of the calcineurin inhibitors
PF Halloran |
Transplantation Proceedings | 2001 |
A placebo-controlled trial to evaluate immunomodulatory effects of paricalcitol
SM Moe, M Zekonis, J Harezlak, WT Ambrosius, CM Gassensmith, CL Murphy, RR Russell, TD Batiuk |
American Journal of Kidney Diseases | 2001 |
Cyclosporin: An Updated Review of the Pharmacokinetic Properties, Clinical Efficacy and Tolerability of a Microemulsion-Based Formulation (Neoral??)* in Organ Transplantation
CJ Dunn, AJ Wagstaff, CM Perry, GL Plosker, KL Goa |
Drugs | 2001 |
Modern Immunosuppressives
HJ Schuurman, G Feutren, JF Bach |
2001 | |
Role of T Cells and Gamma Interferon during Induction of Hypersensitivity to Lipopolysaccharide by Toxic Shock Syndrome Toxin 1 in Mice
JD Clements, MM Dinges, PM Schlievert |
Infection and immunity | 2001 |
Whole-Blood Calcineurin Activity Is Not Predicted by Cyclosporine Blood Concentration in Renal Transplant Recipients
R Caruso, N Perico, D Cattaneo, G Piccinini, S Bonazzola, G Remuzzi, F Gaspari |
Clinical chemistry | 2001 |
Molecular pharmacology of immunosuppressive agents in relation to their clinical use
L Kung, S Gourishankar, PF Halloran |
Current Opinion in Organ Transplantation | 2000 |
NEWCASTLE DISEASE ANTIBODY TITRE IS DEPENDENT ON SERUM CALCIUM CONCENTRATION
J Božičković, G Krivec, WL Ragland, H Mazija, P Božičković, E Prukner-Radovčić |
Acta Veterinaria Hungarica | 2000 |
Inhibition of calcineurin activity and protection against cyclosporine A induced cytotoxicity by prednisolone sodium succinate in human peripheral mononuclear cells
S Sipka, K Szücs, S Szántó, I Kovács, G Lakos, P Antal-Szalmás, G Szegedi, P Gergely |
Immunopharmacology | 2000 |
In vitro effect of retinoids on calcineurin activity
DJ Spannaus-Martin, BL Martin |
Biochemical Pharmacology | 2000 |
IMMUNOPHILINS MAY LIMIT CALCINEURIN INHIBITION BY CYCLOSPORINE AND TACROLIMUS AT HIGH DRUG CONCENTRATIONS1:
L Kung, PF Halloran |
Transplantation | 2000 |
Recommendations for the Outpatient Surveillance of Renal Transplant Recipients
BL Kasiske, MA Vazquez, WE Harmon, RS Brown, GM DANOVITCH, RS Gaston, DA Roth, JD Scandling, GG Singer |
Journal of the American Society of Nephrology : JASN | 2000 |
Ex VivoAssessment of Immunosuppression in Undiluted Whole Blood from Pigs Dosed with Tacrolimus (FK506)
YW Chen, ML Smith, MP Sheets, SJ Ballaron, JM Trevillyan, TA Fey, DM Gauvin, R Kolano, MS Pong, GC Hsieh, J Bauch, K Marsh, G Carter, J Luly, S Djuric, KW Mollison |
Clinical Immunology | 1999 |
Pressure overload induces severe hypertrophy in mice treated with cyclosporine, an inhibitor of calcineurin
B Ding, RL Price, TK Borg, EO Weinberg, PF Halloran, BH Lorell |
Circulation research | 1999 |
HUMAN T CELL RESPONSES TO HUMAN AND PORCINE ENDOTHELIAL CELLS ARE HIGHLY SENSITIVE TO CYCLOSPORIN A AND FK506 IN VITRO1:
P Batten, AM McCormack, CS Page, MH Yacoub, ML Rose |
Transplantation | 1999 |
THE TEMPORAL PROFILE OF CALCINEURIN INHIBITION BY CYCLOSPORINE IN VIVO1:
PF Halloran, LM Helms, L Kung, J Noujaim |
Transplantation | 1999 |
The Effect of Calcium-Related Factors on the Predominance of IFN-γ or Interleukin-4 in Cultured Mononuclear Cells
H Enomoto, S Yousefi, N Vaziri, S Khonsari, J Ocariz, MG Delayarian, T Cesario |
Journal of Interferon & Cytokine Research | 1998 |
New immunosuppressive strategies
PA Keown |
Current Opinion in Nephrology and Hypertension | 1998 |
Calcineurin and the biological effect of cyclosporine and tacrolimus
PF Halloran, L Kung, J Noujaim |
Transplantation Proceedings | 1998 |
New Comprehensive Biochemistry
S Yamamoto |
New Comprehensive Biochemistry | 1983 |