Research Article
P Peraldi, M Xu, B M Spiegelman
Title and authors | Publication | Year |
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Hepatoprotective and Antiatherosclerotic Effects of Oleoylethanolamide-Based Dietary Supplement in Dietary-Induced Obesity in Mice
Ivashkevich D, Ponomarenko A, Manzhulo I, Egoraeva A, Dyuizen I |
Pathophysiology | 2025 |
Molecular and pathophysiological relationship between obesity and chronic inflammation in the manifestation of metabolic dysfunctions and their inflammation‑mediating treatment options (Review).
Varra FN, Varras M, Varra VK, Theodosis-Nobelos P |
Molecular medicine reports | 2024 |
Development of PPARγ Agonists for the Treatment of Neuroinflammatory and Neurodegenerative Diseases: Leriglitazone as a Promising Candidate.
Pizcueta P, Vergara C, Emanuele M, Vilalta A, Rodríguez-Pascau L, Martinell M |
International journal of molecular sciences | 2023 |
Molecular Mechanisms for the Vicious Cycle between Insulin Resistance and the Inflammatory Response in Obesity
Szukiewicz D |
International journal of molecular sciences | 2023 |
Flavonoid compound from Agrimonia pilosa Ledeb improves adipose insulin resistance by alleviating oxidative stress and inflammation.
Guo T, Pan Y, Yang L, Chen G, Deng J, Zhu L |
2023 | |
Saffron as a promising therapy for diabetes and Alzheimer's disease: mechanistic insights.
Sanaie S, Nikanfar S, Kalekhane ZY, Azizi-Zeinalhajlou A, Sadigh-Eteghad S, Araj-Khodaei M, Ayati MH, Andalib S |
Metabolic Brain Disease | 2022 |
From Food to Genes: Transcriptional Regulation of Metabolism by Lipids and Carbohydrates
I Bravo-Ruiz, MÁ Medina, B Martínez-Poveda |
Nutrients | 2021 |
The role of peroxisome proliferator-activated receptors (PPAR) in immune responses
A Christofides, E Konstantinidou, C Jani, VA Boussiotis |
Metabolism | 2021 |
Metabolic Messengers: tumour necrosis factor
JK Sethi, GS Hotamisligil |
2021 | |
Effects of melatonin on insulin signaling and inflammatory pathways of rats with apical periodontitis
BS Tavares, TV Tsosura, MS Mattera, JO Santelli, BE Belardi, FY Chiba, LT Cintra, CC Silva, DH Matsushita |
International Endodontic Journal | 2021 |
Therapeutic Potentials of Colocasia affinis Leaf Extract for the Alleviation of Streptozotocin-Induced Diabetes and Diabetic Complications: In vivo and in silico-Based Studies
MC Shill, AK Bepari, M Khan, Z Tasneem, T Ahmed, A Hasan, J Alam, M Hossain, A Rahman, ShazidSharker, M Shahriar, GM Rahman, HM Reza |
Journal of inflammation research | 2021 |
Immune Cells Gate White Adipose Tissue Expansion
AR Cox, N Chernis, PM Masschelin, SM Hartig |
Endocrinology | 2019 |
Therapeutic Mechanisms of Herbal Medicines Against Insulin Resistance: A Review
J Li, L Bai, F Wei, J Zhao, D Wang, Y Xiao, W Yan, J Wei |
Frontiers in pharmacology | 2019 |
Lifestyle and Food Habits Impact on Chronic Diseases: Roles of PPARs
M dAngelo, V Castelli, MG Tupone, M Catanesi, A Antonosante, R Dominguez-Benot, R Ippoliti, AM Cimini, E Benedetti |
International journal of molecular sciences | 2019 |
Remodeling adipose tissue inflammasome for type 2 diabetes mellitus treatment: Current perspective and translational strategies
A Banerjee, J Singh |
Bioengineering & Translational Medicine | 2019 |
Nuclear Receptors in the Pathogenesis and Management of Inflammatory Bowel Disease
L Ning, X Lou, F Zhang, G Xu |
Mediators of Inflammation | 2019 |
Larger omental adipocytes correlate with greater Fetuin-A reduction following sleeve gastrectomy
KN Robinson, B Rowitz, UJ Oliphant, SM Donovan, M Teran-Garcia |
BMC Obesity | 2019 |
PPARγ: Potential Therapeutic Target for Ailments Beyond Diabetes and its Natural Agonism
S Shafi, P Gupta, GL Khatik, J Gupta |
Current drug targets | 2019 |
Some important peptides and their role in obesity-current insights
N Shama, R Kumari, S Bais, A Shrivastava |
Obesity Medicine | 2019 |
Re-highlighting the action of PPARγ in treating metabolic diseases
SH Choi, SS Chung, KS Park |
F1000Research | 2018 |
PPARs and Metabolic Disorders Associated with Challenged Adipose Tissue Plasticity
P Corrales, A Vidal-Puig, G Medina-Gómez |
International journal of molecular sciences | 2018 |
Adapting to obesity with adipose tissue inflammation
SM Reilly, AR Saltiel |
Nature Reviews Endocrinology | 2017 |
Macrophage JAK2 deficiency protects against high-fat diet-induced inflammation
HR Desai, T Sivasubramaniyam, XS Revelo, SA Schroer, CT Luk, PR Rikkala, AH Metherel, DW Dodington, YJ Park, MJ Kim, JA Rapps, R Besla, CS Robbins, KU Wagner, RP Bazinet, DA Winer, M Woo |
Scientific Reports | 2017 |
PPARs in the central nervous system: roles in neurodegeneration and neuroinflammation: PPARs in the CNS and neurodegenerative diseases
JM Zolezzi, MJ Santos, S Bastías-Candia, C Pinto, JA Godoy, NC Inestrosa |
Biological Reviews | 2017 |
Pioglitazone improves insulin sensitivity and reduces weight loss in Walker-256 tumor-bearing rats
FF Silva, M Ortiz-Silva, WB de Galia, P Cassolla, MF Graciano, CT Zaia, D Zaia, ÂR Carpinelli, FG da Silva, HM de Souza |
Life Sciences | 2017 |
Impairment of the activin A autocrine loop by lopinavir reduces self-renewal of distinct human adipose progenitors
C Ravaud, M Paré, S Azoulay, C Dani, A Ladoux |
Scientific Reports | 2017 |
From chronic overnutrition to metaflammation and insulin resistance: adipose tissue and liver contributions
T Caputo, F Gilardi, B Desvergne |
FEBS Letters | 2017 |
Metaflammatory responses during obesity: Pathomechanism and treatment
M Debnath, S Agrawal, A Agrawal, GP Dubey |
Obesity Research & Clinical Practice | 2016 |
Isoliquiritigenin Attenuates Adipose Tissue Inflammation in vitro and Adipose Tissue Fibrosis through Inhibition of Innate Immune Responses in Mice
Y Watanabe, Y Nagai, H Honda, N Okamoto, S Yamamoto, T Hamashima, Y Ishii, M Tanaka, T Suganami, M Sasahara, K Miyake, K Takatsu |
Scientific Reports | 2016 |
Therapeutic potential of the dual peroxisome proliferator activated receptor (PPAR)α/γ agonist aleglitazar in attenuating TNF-α-mediated inflammation and insulin resistance in human adipocytes
M Massaro, E Scoditti, M Pellegrino, MA Carluccio, N Calabriso, M Wabitsch, C Storelli, M Wright, RD Caterina |
Pharmacological Research | 2016 |
August's Consultations in Feline Internal Medicine, Volume 7
S Niessen |
August's Consultations in Feline Internal Medicine, Volume 7 | 2016 |
Nonerythropoietic Erythropoietin-Derived Peptide Suppresses Adipogenesis, Inflammation, Obesity and Insulin Resistance
Y Liu, B Luo, R Shi, J Wang, Z Liu, W Liu, S Wang, Z Zhang |
Scientific Reports | 2015 |
Effects of pioglitazone on cardiac and adipose tissue pathology in rats with metabolic syndrome
N Matsuura, C Asano, K Nagasawa, S Ito, Y Sano, Y Minagawa, Y Yamada, T Hattori, S Watanabe, T Murohara, K Nagata |
International Journal of Cardiology | 2015 |
IER3 Promotes Expansion of Adipose Progenitor Cells in Response to Changes in Distinct Microenvironmental Effectors: IER3 Maintains Stem Cell Potency of Adipose Progenitor Cells
C Ravaud, D Esteve, P Villageois, A Bouloumie, C Dani, A Ladoux |
Stem Cells | 2015 |
International Textbook of Diabetes Mellitus: DeFronzo/International Textbook of Diabetes Mellitus, Fourth Edition
RN Bergman, M Ader |
International Textbook of Diabetes Mellitus: DeFronzo/International Textbook of Diabetes Mellitus, Fourth Edition | 2015 |
4-Hydroxyisoleucine ameliorates an insulin resistant-like state in 3T3-L1 adipocytes by regulating TACE/TIMP3 expression
F Gao, W Du, MI Zafar, RA Shafqat, L Jian, Q Cai, F Lu |
Drug design, development and therapy | 2015 |
Revisiting PPARγ as a target for the treatment of metabolic disorders
Choi SS, Park J, Choi JH |
BMB Reports | 2014 |
Revisiting PPARγ as a target for the treatment of metabolic disorders
Sun-Sil Choi, Jiyoung Park, Jang Hyun Choi |
BMB Reports | 2014 |
STAT1, NF-κB and ERKs play a role in the induction of lipocalin-2 expression in adipocytes
P Zhao, JM Stephens |
Molecular Metabolism | 2013 |
Modulation of insulin resistance by PUFA in metabolic tissues
M Kopál, J Muchová, Z Ďuračková |
European Journal of Lipid Science and Technology | 2013 |
Protective Effects of Vescalagin from Pink Wax Apple [Syzygium samarangense (Blume) Merrill and Perry] Fruit against Methylglyoxal-Induced Inflammation and Carbohydrate Metabolic Disorder in Rats
WC Chang, SC Shen, JS Wu |
Journal of Agricultural and Food Chemistry | 2013 |
Lactational Exposure of Phthalate Impairs Insulin Signaling in the Cardiac Muscle of F1 Female Albino Rats
VM Priya, C Mayilvanan, N Akilavalli, P Rajesh, K Balasubramanian |
Cardiovascular Toxicology | 2013 |
Fraction from Wax Apple [Syzygium samarangense (Blume) Merrill and Perry] Fruit Extract Ameliorates Insulin Resistance via Modulating Insulin Signaling and Inflammation Pathway in Tumor Necrosis Factor α-Treated FL83B Mouse Hepatocytes
SC Shen, WC Chang, CL Chang |
International journal of molecular sciences | 2012 |
Carbonic anhydrase III regulates peroxisome proliferator-activated receptor-γ2
MC Mitterberger, G Kim, U Rostek, RL Levine, W Zwerschke |
Experimental Cell Research | 2012 |
Inflammation as a Link between Obesity and Metabolic Syndrome
F Emanuela, M Grazia, DR Marco, LM Paola, F Giorgio, B Marco |
Journal of nutrition and metabolism | 2012 |
Metabolic inflammation: Connecting obesity and insulin resistance
N Dali-Youcef, M Mecili, R Ricci, E Andrès |
Annals of Medicine | 2012 |
Inflammatory mechanisms in obesity
MF Gregor, GS Hotamisligil |
Annual Review of Immunology | 2011 |
Insulin Signaling and Insulin Sensitizing in Muscle and Liver of Obese Monkeys: Peroxisome Proliferator-Activated Receptor Gamma Agonist Improves Defective Activation of Atypical Protein Kinase C
HK Ortmeyer, MP Sajan, A Miura, Y Kanoh, J Rivas, Y Li, ML Standaert, AS Ryan, NL Bodkin, RV Farese, BC Hansen |
Antioxidants & Redox Signaling | 2011 |
The Metabolic Syndrome
S Devaraj, D Siegel, I Jialal |
The Metabolic Syndrome | 2011 |
Mast cells squeeze the heart and stretch the gird: Their role in atherosclerosis and obesity
TC Theoharides, N Sismanopoulos, DA Delivanis, B Zhang, EE Hatziagelaki, D Kalogeromitros |
Trends in Pharmacological Sciences | 2011 |
Williams Textbook of Endocrinology
DW Cooke, SA Divall, S Radovick |
Williams Textbook of Endocrinology | 2011 |
Targeting Inflammation-Induced Obesity and Metabolic Diseases by Curcumin and Other Nutraceuticals
BB Aggarwal |
Annual Review of Nutrition | 2010 |
Molecular determinants of the cardiometabolic phenotype
L las Fuentes, G Simone, DK Arnett, VG Dávila-Román |
Endocrine, metabolic & immune disorders drug targets | 2010 |
Rosiglitazone increases cell surface GLUT4 levels in 3T3-L1 adipocytes through an enhancement of endosomal recycling
L Martinez, M Berenguer, MC Bruce, YL Marchand-Brustel, R Govers |
Biochemical Pharmacology | 2010 |
Peroxisome Proliferator–Activated Receptors and The Metabolic Syndrome
A Meiliana, A Wijaya |
The Indonesian Biomedical Journal | 2009 |
S6K directly phosphorylates IRS-1 on Ser-270 to promote insulin resistance in response to TNF-(alpha) signaling through IKK2
J Zhang, Z Gao, J Yin, MJ Quon, J Ye |
The Journal of biological chemistry | 2008 |
TNF-α and adipocyte biology
WP Cawthorn, JK Sethi |
FEBS Letters | 2008 |
PPAR Action in Human Placental Development and Pregnancy and Its Complications
F Wieser, L Waite, C Depoix, RN Taylor |
PPAR Research | 2008 |
Peroxisome Proliferator-Activated Receptors (PPARs) and the Human Skin
P Sertznig, M Seifert, W Tilgen, J Reichrath |
American Journal of Clinical Dermatology | 2008 |
Effect of pioglitazone and rosiglitazone on mediators of endothelial dysfunction, markers of angiogenesis and inflammatory cytokines in type-2 diabetes
SK Vijay, M Mishra, H Kumar, K Tripathi |
Acta Diabetologica | 2008 |
Thiazolidinedione derivatives in diabetes and cardiovascular disease: an update
PA Sarafidis |
Fundamental & Clinical Pharmacology | 2008 |
Inflammation and Insulin Resistance in Uremia
M Zanetti, R Barazzoni, G Guarnieri |
Journal of Renal Nutrition | 2008 |
Thiazolidinediones are partial agonists for the glucocorticoid receptor
L Matthews, A Berry, M Tersigni, F D'Acquisto, A Ianaro, D Ray |
Endocrinology | 2008 |
S6K Directly Phosphorylates IRS-1 on Ser-270 to Promote Insulin Resistance in Response to TNF-α Signaling through IKK2
J Zhang, Z Gao, J Yin, MJ Quon, J Ye |
The Journal of biological chemistry | 2008 |
Type 2 Diabetes Mellitus
MN Feinglos, MA Bethel |
2008 | |
Hypoglycemic action of thiazolidinediones/peroxisome proliferator-activated receptor gamma by inhibition of the c-Jun NH2-terminal kinase pathway
J Díaz-Delfín, M Morales, C Caelles |
Diabetes | 2007 |
'Striking the Right Balance' in Targeting PPARgamma in the Metabolic Syndrome: Novel Insights from Human Genetic Studies
M Gurnell |
PPAR Research | 2007 |
Tumour necrosis factor-? in human adipose tissue ? from signalling mechanisms to clinical implications
M Rydén, P Arner |
Journal of Internal Medicine | 2007 |
Transcription Factor Profile by Degenerate RT-PCR/SSCP - Application in 3T3-L1 Adipocyte Treated with TNF- α -
YL Kim, SH Lee, YK Choi, SY Chang, YS Kim, SK Kim, SW Park, WK Park, YW Cho, SJ Lee |
The Journal of Korean Diabetes Association | 2007 |
Present concepts and future outlook: Function of peroxisome proliferator-activated receptors (PPARs) for pathogenesis, progression, and therapy of cancer
P Sertznig, M Seifert, W Tilgen, J Reichrath |
Journal of Cellular Physiology | 2007 |
Agonism of Peroxisome Proliferator Receptor-Gamma may have Therapeutic Potential for Neuroinflammation and Parkinson's Disease
LH Randy, B Guoying |
Current neuropharmacology | 2007 |
Effects of Simvastatin and Metformin on Inflammation and Insulin Resistance in Individuals with Mild Metabolic Syndrome
C Bulc??o, FF Ribeiro-Filho, A Sa??udo, SG Ferreira |
American Journal of Cardiovascular Drugs | 2007 |
Depot-specific regulation of perilipin by rosiglitazone in a diabetic animal model
HJ Kim, TW Jung, ES Kang, DJ Kim, CW Ahn, KW Lee, HC Lee, BS Cha |
Metabolism | 2007 |
Tratamiento de enfermedades metabólicas mediante la modulación del PPARγ
XP Tarridas |
Clínica e Investigación en Arteriosclerosis | 2007 |
The relationship between the metabolic syndrome and energy-utilization deficit in the pathogenesis of obesity-induced osteoarthritis
J Rojas-Rodríguez, LE Escobar-Linares, M Garcia-Carrasco, RO Escárcega, S Fuentes-Alexandro, A Zamora-Ustaran |
Medical Hypotheses | 2007 |
Contemporary Targeted Therapies in Rheumatology
P Lent, W Berg |
Contemporary Targeted Therapies in Rheumatology | 2007 |
Suppression of PPAR-γ attenuates insulin-stimulated glucose uptake by affecting both GLUT1 and GLUT4 in 3T3-L1 adipocytes
W Liao, MT Nguyen, T Yoshizaki, S Favelyukis, D Patsouris, T Imamura, IM Verma, JM Olefsky |
American journal of physiology. Endocrinology and metabolism | 2007 |
Insulin Facilitates the Hepatic Clearance of Plasma Amyloid β-Peptide (1–40) by Intracellular Translocation of Low-Density Lipoprotein Receptor-Related Protein 1 (LRP-1) to the Plasma Membrane in Hepatocytes
C Tamaki, S Ohtsuki, T Terasaki |
Molecular pharmacology | 2007 |
Palmitate Induces Tumor Necrosis Factor-α Expression in C2C12 Skeletal Muscle Cells by a Mechanism Involving Protein Kinase C and Nuclear Factor-κB Activation
M Jové, A Planavila, RM Sánchez, M Merlos, JC Laguna, M Vázquez-Carrera |
Endocrinology | 2006 |
The role of insulin and neurotrophic factor signaling in brain aging and Alzheimer's Disease
GM Cole, SA Frautschy |
Experimental Gerontology | 2006 |
PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS: How Their Effects on Macrophages Can Lead to the Development of a New Drug Therapy Against Atherosclerosis
AC Li, W Palinski |
Annual Review of Pharmacology and Toxicology | 2006 |
Peroxisome proliferator-activated receptors and inflammation
LA Moraes, L Piqueras, D Bishop-Bailey |
Pharmacology & Therapeutics | 2006 |
Biochemical mechanism of insulin sensitization, lipid modulation and anti-atherogenic potential of PPAR α/γ dual agonist: Ragaglitazar
S Sharma, A Sowjanya, M Kumari, R Suryaprakash, G Cynthia, J Suresh, R Chakrabarti |
Life Sciences | 2006 |
Adipokines and the signaling role of adipose tissue in inflammation and obesity
IS Wood, P Trayhurn |
Future Lipidology | 2006 |
PPAR agonists treatment is effective in a nonalcoholic fatty liver disease animal model by modulating fatty-acid metabolic enzymes
YS Seo, JH Kim, NY Jo, KM Choi, SH Baik, JJ Park, JS Kim, KS Byun, YT Bak, CH Lee, AR Kim, JE Yeon |
Journal of Gastroenterology and Hepatology | 2006 |
Glucose-lowering effect of powder formulation of African black tea extract in KK-Ay/TaJcl diabetic mouse
Y Shoji, H Nakashima |
Archives of Pharmacal Research | 2006 |
Tetrahydroisoquinoline PPARγ agonists: Design of novel, highly selective non-TZD antihyperglycemic agents
JR Henry, Y Li, AM Warshawsky, JT Brozinick, ED Hawkins, EA Misener, DA Briere, C Montrose-Rafizadeh, RW Zink, NP Yumibe, RT Ajamie, B Wilken, V Devanarayan |
Bioorganic & Medicinal Chemistry Letters | 2006 |
Nuclear receptors as drug targets in metabolic diseases: new approaches to therapy
JF Tobin, LP Freedman |
Trends in Endocrinology & Metabolism | 2006 |
Adiponectine et syndrome métabolique
MJ Kim, M Maachi, J Capeau, JP Bastard |
Immuno-analyse & Biologie Spécialisée | 2006 |
Pediatric Endocrinology: Obesity, Diabetes Mellitus, Insulin Resistance, and Hypoglycemia
M Haller, J Silverstein, A Rosenbloom |
Pediatric Endocrinology: Obesity, Diabetes Mellitus, Insulin Resistance, and Hypoglycemia | 2006 |
Thiazolidinediones can rapidly activate AMP-activated protein kinase in mammalian tissues
NK LeBrasseur, M Kelly, TS Tsao, SR Farmer, AK Saha, NB Ruderman, E Tomas |
American journal of physiology. Endocrinology and metabolism | 2006 |
The adipose tissue triglyceride lipase ATGL/PNPLA2 is downregulated by insulin and TNF-α in 3T3-L1 adipocytes and is a target for transactivation by PPARγ
JY Kim, K Tillison, JH Lee, DA Rearick, CM Smas |
American journal of physiology. Endocrinology and metabolism | 2006 |
Stress, the Endoplasmic Reticulum, and Insulin Resistance
PC Tsiotra, C Tsigos |
Annals of the New York Academy of Sciences | 2006 |
A Novel Partial Agonist of Peroxisome Proliferator-Activated Receptor-γ (PPARγ) Recruits PPARγ-Coactivator-1α, Prevents Triglyceride Accumulation, and Potentiates Insulin Signaling in Vitro
E Burgermeister, A Schnoebelen, A Flament, J Benz, M Stihle, B Gsell, A Rufer, A Ruf, B Kuhn, HP Märki, J Mizrahi, E Sebokova, E Niesor, M Meyer |
Molecular Endocrinology | 2006 |
The effect of PPARgamma ligands on the adipose tissue in insulin resistance
A Hammarstedt, CX Andersson, VR Sopasakis, U Smith |
Prostaglandins, leukotrienes, and essential fatty acids | 2005 |
Implication of the Pro12Ala polymorphism of the PPAR-gamma 2gene in type 2 diabetes and obesity in the French population
M Ghoussaini, D Meyre, S Lobbens, G Charpentier, K Clément, MA Charles, M Tauber, J Weill, P Froguel |
BMC Medical Genetics | 2005 |
Receptores activados por proliferadores peroxisómicos tipo gamma en el síndrome metabólico: ¿amigos o enemigos?
MV Carrera |
Clínica e Investigación en Arteriosclerosis | 2005 |
Angiopoietin-related growth factor antagonizes obesity and insulin resistance
Y Oike, M Akao, K Yasunaga, T Yamauchi, T Morisada, Y Ito, T Urano, Y Kimura, Y Kubota, H Maekawa, T Miyamoto, K Miyata, S Matsumoto, J Sakai, N Nakagata, M Takeya, H Koseki, Y Ogawa, T Kadowaki, T Suda |
Nature Medicine | 2005 |
Lifestyle modification and endothelial function in obese subjects
O Hamdy |
Expert Review of Cardiovascular Therapy | 2005 |
Angiopoietin-like proteins: potential new targets for metabolic syndrome therapy
Y Oike, M Akao, Y Kubota, T Suda |
Trends in Molecular Medicine | 2005 |
AMPK activation as a strategy for reversing the endothelial lipotoxicity underlying the increased vascular risk associated with insulin resistance syndrome
MF McCarty |
Medical Hypotheses | 2005 |
Peroxisome proliferator-activated receptor γ and the regulation of adipocyte function: lessons from human genetic studies
M Gurnell |
Best Practice & Research Clinical Endocrinology & Metabolism | 2005 |
Sleep Apnea and Metabolic Dysfunction
NM Punjabi, BA Beamer |
Principles and Practice of Sleep Medicine | 2005 |
Principles and Practice of Sleep Medicine
NM Punjabi, BA Beamer |
Principles and Practice of Sleep Medicine | 2005 |
Proinflammatory adipocytokines induce TIMP-1 expression in 3T3-L1 adipocytes
S Kralisch, J Klein, U Lossner, M Bluher, R Paschke, M Stumvoll, M Fasshauer |
FEBS Letters | 2005 |
A role for sphingolipids in producing the common features of type 2 diabetes, metabolic syndrome X, and Cushing's syndrome
Scott A Summers, Don H Nelson |
Diabetes | 2005 |
Interleukin-6 is a negative regulator of visfatin gene expression in 3T3-L1 adipocytes
S Kralisch, J Klein, U Lossner, M Bluher, R Paschke, M Stumvoll, M Fasshauer |
American journal of physiology. Endocrinology and metabolism | 2005 |
Metabolic Effects of Melatonin on Oxidative Stress and Diabetes Mellitus
S Nishida |
Endocrine | 2005 |
Inflammation, stress, and diabetes.
Wellen KE, Hotamisligil GS |
Journal of Clinical Investigation | 2005 |
Increased CD36 Protein as a Response to Defective Insulin Signaling in Macrophages
Chien-Ping Liang, Seongah Han, Haruka Okamoto, Ronald Carnemolla, Ira Tabas, Domenico Accili, Alan R. Tall |
Journal of Clinical Investigation | 2004 |
Rosiglitazone ameliorates insulin resistance in brown adipocytes of Wistar rats by impairing TNF-α induction of p38 and p42/p44 mitogen-activated protein kinases
R Hernandez, T Teruel, C de Alvaro, M Lorenzo |
Diabetologia | 2004 |
Gender differences in TNF-alpha levels among obese vs nonobese Latino children
D Dixon, R Goldberg, N Schneiderman, A Delamater |
European Journal of Clinical Nutrition | 2004 |
Unliganded RXR acts as an inhibitory factor on troglitazone-induced activation
T Monden, M Yamada, Y Nihei, M Kishi, T Tomaru, S Ishii, T Hashida, N Shibusawa, K Hashimoto, T Satoh, K Kasai, M Mori |
Life Sciences | 2004 |
Diabetes Prolongs the Inflammatory Response to a Bacterial Stimulus Through Cytokine Dysregulation
G Naguib, H Al-Mashat, T Desta, DT Graves |
Journal of Investigative Dermatology | 2004 |
Resistance training enhances insulin-mediated glucose disposal with minimal effect on the tumor necrosis factor-alpha system in older hypertensives
TH Reynolds, MA Supiano, DR Dengel |
Metabolism | 2004 |
Expression of PPAR, RXR isoforms and fatty acid transporting proteins in the rat and human gastrointestinal tracts
Q Wang, D Herrera-Ruiz, AS Mathis, TJ Cook, RK Bhardwaj, GT Knipp |
Journal of Pharmaceutical Sciences | 2004 |
PPARs and the complex journey to obesity
RM Evans, GD Barish, YX Wang |
Nature Medicine | 2004 |
Adipocyte biology and adipocytokines
WA Haque, A Garg |
Clinics in Laboratory Medicine | 2004 |
PPAR- and LXR-dependent pathways controlling lipid metabolism and the development of atherosclerosis
AC Li, CK Glass |
Journal of lipid research | 2004 |
Gender differences in TNF-α levels among obese vs nonobese Latino children
D Dixon, R Goldberg, N Schneiderman, A Delamater |
European Journal of Clinical Nutrition | 2004 |
Tumor necrosis factor-α inhibits peroxisome proliferator-activated receptor γ activity at a posttranslational level in hepatic stellate cells
CK Sung, H She, S Xiong, H Tsukamoto |
AJP Gastrointestinal and Liver Physiology | 2004 |
Transcription Suppression of Peroxisome Proliferator-Activated Receptor γ2 Gene Expression by Tumor Necrosis Factor α via an Inhibition of CCAAT/ Enhancer-binding Protein δ during the Early Stage of Adipocyte Differentiation
M Kudo, A Sugawara, A Uruno, K Takeuchi, S Ito |
Endocrinology | 2004 |
Thiazolidinediones in type 2 diabetes mellitus: current clinical evidence.
Diamant M, Heine RJ |
Drugs | 2003 |
International Textbook of Diabetes Mellitus
RA DeFronzo, L Mandarino, E Ferrannini |
International Textbook of Diabetes Mellitus | 2003 |
TNF-? induction of lipolysis is mediated through activation of the extracellular signal related kinase pathway in 3T3-L1 adipocytes
SC Souza, HJ Palmer, YH Kang, MT Yamamoto, KV Muliro, KE Paulson, AS Greenberg |
Journal of Cellular Biochemistry | 2003 |
PPAR-γ, TNF-α Messenger RNA levels and lipase activity in the pregnant and lactating rat
K Kawaguchi, T Sugiyama, H Hibasami, N Toyoda |
Life Sciences | 2003 |
Effect of thiazolidinediones on glucose and fatty acid metabolism in patients with type 2 diabetes
G Boden, P Cheung, M Mozzoli, SK Fried |
Metabolism | 2003 |
Handbook of Cell Signaling
MF White |
Handbook of Cell Signaling | 2003 |
The metabolic syndrome and type 2 diabetes: role of the adipocyte:
R McPherson, PH Jones |
Current Opinion in Lipidology | 2003 |
¿Debemos incluir la determinación de la resistina en la práctica clínica?
MA Rubio |
Endocrinología y Nutrición | 2003 |
Effects of troglitazone in young first-degree relatives of patients with type 2 diabetes
Klaus Levin, Ole Hother-Nielsen, Jan Erik Henriksen, Henning Beck-Nielsen |
Diabetes care | 2003 |
Troglitazone Antagonizes Tumor Necrosis Factor-α-induced Reprogramming of Adipocyte Gene Expression by Inhibiting the Transcriptional Regulatory Functions of NF-κB
H Ruan, HJ Pownall, HF Lodish |
The Journal of biological chemistry | 2003 |
Progress in Drug Research
H Wu, EJ Lien, LL Lien, RM Schultz, VJ Ram, E Domingo, P Spence, SP Gupta, SP Bhat, EC Villarreal, E Jucker |
2003 | |
Three Mitogen-Activated Protein Kinases Inhibit Insulin Signaling by Different Mechanisms in 3T3-L1 Adipocytes
M Fujishiro, Y Gotoh, H Katagiri, H Sakoda, T Ogihara, M Anai, Y Onishi, H Ono, M Abe, N Shojima, Y Fukushima, M Kikuchi, Y Oka, T Asano |
Molecular Endocrinology | 2003 |
Metabolic and Additional Vascular Effects of Thiazolidinediones:
FM Martens, FL Visseren, J Lemay, EJ de Koning, TJ Rabelink |
Drugs | 2002 |
The mechanisms of action of PPARs
J Berger, DE Moller |
Annual Review of Medicine | 2002 |
Adipogenesis and aging: does aging make fat go MAD?
JL Kirkland, T Tchkonia, T Pirtskhalava, J Han, I Karagiannides |
Experimental Gerontology | 2002 |
Identifying the links between obesity, insulin resistance and beta-cell function: potential role of adipocyte-derived cytokines in the pathogenesis of type 2 diabetes
AS Greenberg, ML McDaniel |
European Journal of Clinical Investigation | 2002 |
Ligands of Peroxisome Proliferator-activated Receptor-γ Induce Apoptosis in AR42J Cells
A Masamune, K Satoh, Y Sakai, M Yoshida, A Satoh, T Shimosegawa |
Pancreas | 2002 |
Physiological and Therapeutic Roles of Peroxisome Proliferator-Activated Receptors
J Berger, JA Wagner |
Diabetes Technology & Therapeutics | 2002 |
Stimulation of Peroxisome Proliferator-Activated Receptors α and γ Blocks HIV-1 Replication and TNFα Production in Acutely Infected Primary Blood Cells, Chronically Infected U1 Cells, and Alveolar Macrophages From HIV-Infected Subjects
PR Skolnik, MF Rabbi, JM Mathys, AS Greenberg |
JAIDS Journal of Acquired Immune Deficiency Syndromes | 2002 |
Troglitazone: the discovery and development of a novel therapy for the treatment of Type 2 diabetes mellitus
JC Parker |
Advanced Drug Delivery Reviews | 2002 |
Thiazolidinediones in the treatment of Type 2 diabetes
AS Greenberg, AG Pittas |
Expert Opinion on Pharmacotherapy | 2002 |
Expression of PPAR and RXR Isoforms in the Developing Rat and Human Term Placentas
Q Wang, H Fujii, GT Knipp |
Placenta | 2002 |
Improved Insulin Sensitivity and Body Fat Distribution in HIV-Infected Patients Treated With Rosiglitazone: A Pilot Study
MC Gelato, DC Mynarcik, JL Quick, RT Steigbigel, J Fuhrer, CE Brathwaite, JS Brebbia, MR Wax, MA McNurlan |
JAIDS Journal of Acquired Immune Deficiency Syndromes | 2002 |
The mode of action of thiazolidinediones
H Hauner |
Diabetes/Metabolism Research and Reviews | 2002 |
Management of Rosiglitazone-Induced Edema: Two Case Reports and a Review of the Literature
F Wang, LM Aleksunes, LA Reagan, CM Vergara |
Diabetes Technology & Therapeutics | 2002 |
Differential effect of PPARγ2 variants in the development of type 2 diabetes between native Japanese and Japanese Americans
M Nemoto, T Sasaki, SS Deeb, WY Fujimoto, N Tajima |
Diabetes Research and Clinical Practice | 2002 |
Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro
A Galli, DW Crabb, E Ceni, R Salzano, T Mello, G Svegliati-Baroni, F Ridolfi, L Trozzi, C Surrenti, A Casini |
Gastroenterology | 2002 |
Troglitazone but not Metformin Restores Insulin-Stimulated Phosphoinositide 3-Kinase Activity and Increases p110 Protein Levels in Skeletal Muscle of Type 2 Diabetic Subjects
YB Kim, TP Ciaraldi, A Kong, D Kim, N Chu, P Mohideen, S Mudaliar, RR Henry, BB Kahn |
Diabetes | 2002 |
C2-Ceramide Influences the Expression and Insulin-Mediated Regulation of Cyclic Nucleotide Phosphodiesterase 3B and Lipolysis in 3T3-L1 Adipocytes
J Mei, LS Holst, TR Landstrom, C Holm, D Brindley, V Manganiello, E Degerman |
Diabetes | 2002 |
Potentiation of Insulin Signaling in Tissues of Zucker Obese Rats After Acute and Long-Term Treatment With PPAR Agonists
G Jiang, Q Dallas-Yang, Z Li, D Szalkowski, F Liu, X Shen, M Wu, G Zhou, T Doebber, J Berger, DE Moller, BB Zhang |
Diabetes | 2002 |
Tumor Necrosis Factor- Suppresses Adipocyte-Specific Genes and Activates Expression of Preadipocyte Genes in 3T3-L1 Adipocytes: Nuclear Factor- B Activation by TNF- Is Obligatory
H Ruan, N Hacohen, TR Golub, LV Parijs, HF Lodish |
Diabetes | 2002 |
Lipolysis in the Absence of Hormone-Sensitive Lipase: Evidence for a Common Mechanism Regulating Distinct Lipases
H Okazaki, J Osuga, Y Tamura, N Yahagi, S Tomita, F Shionoiri, Y Iizuka, K Ohashi, K Harada, S Kimura, T Gotoda, H Shimano, N Yamada, S Ishibashi |
Diabetes | 2002 |
Troglitazone: A Possible Modulator of Ovarian Steroidogenesis
MF Mitwally, SF Witchel, RF Casper |
Journal of the Society for Gynecologic Investigation | 2002 |
Impaired (‘diabetic’) insulin signaling and action occur in fat cells long before glucose intolerance—is insulin resistance initiated in the adipose tissue?
U Smith |
International Journal of Obesity | 2002 |
Skeletal muscle triglycerides lowering is associated with net improvement of insulin sensitivity, TNF-α reduction and GLUT4 expression enhancement
G Mingrone, G Rosa, PD Rocco, M Manco, E Capristo, M Castagneto, R Vettor, G Gasbarrini, AV Greco |
International Journal of Obesity | 2002 |
PPAR-γ ligands modulate effects of LPS in stimulated rat synovial fibroblasts
MA Simonin, K Bordji, S Boyault, A Bianchi, E Gouze, P Bécuwe, M Dauça, P Netter, B Terlain |
American journal of physiology. Cell physiology | 2002 |
Peroxisome Proliferator Activated Receptors: From Basic Science to Clinical Applications
JC Fruchart, AM Gotto, R Paoletti, B Staels, AL Catapano |
2002 | |
PPARadigms and PPARadoxes: expanding roles for PPARγ in the control of lipid metabolism
R Walczak, P Tontonoz |
Journal of lipid research | 2002 |
Regulation of Semicarbazide-Sensitive Amine Oxidase Expression by Tumor Necrosis Factor-α in Adipocytes: Functional Consequences on Glucose Transport
N Mercier, M Moldes, KE Hadri, B Fève |
The Journal of pharmacology and experimental therapeutics | 2002 |
Peroxisome proliferator-activated receptors (PPARs): Novel therapeutic targets in renal disease
YF Guan, MD Breyer |
Kidney International | 2001 |
Free fatty acids - do they play a central role in type 2 diabetes?
P Arner |
Diabetes, Obesity and Metabolism | 2001 |
Pro-inflammatory cytokines and adipose tissue
SW Coppack |
Proceedings of the Nutrition Society | 2001 |
Synergistic Antiadipogenic Effects of HIV Type 1 Protease Inhibitors with Tumor Necrosis Factorα: Suppression of Extracellular Insulin Action Mediated by Extracellular Matrix-Degrading Proteases
D Mondal, VF Larussa, KC Agrawal |
AIDS Research and Human Retroviruses | 2001 |
Resistin: a new link between obesity and insulin resistance?
A Vidal-Puig, S O'Rahilly |
Clinical Endocrinology | 2001 |
TNFα Inhibits Insulin's Antiapoptotic Signaling in Vascular Smooth Muscle Cells
S Goetze, F Blaschke, P Stawowy, D Bruemmer, C Spencer, K Graf, M Gräfe, RE Law, E Fleck |
Biochemical and Biophysical Research Communications | 2001 |
Differential Regulation of Adipocytokine mRNAs by Rosiglitazone in db/db Mice
GB Moore, H Chapman, JC Holder, CA Lister, V Piercy, SA Smith, JC Clapham |
Biochemical and Biophysical Research Communications | 2001 |
Troglitazone Enhances Glucose Uptake Induced By alpha-Adrenoceptor Stimulation Via Phosphatidylinositol 3-Kinase In Rat Heart
J Yoshioka, H Kusuoka, K Imahashi, K Hashimoto, M Hori, T Terakawa, T Nishimura |
Clinical and Experimental Pharmacology and Physiology | 2001 |
Prospects for prevention and treatment of cancer with selective PPARγ modulators (SPARMs)
MB Sporn, N Suh, DJ Mangelsdorf |
Trends in Molecular Medicine | 2001 |
Insulin resistance induced in dairy steers by tumor necrosis factor alpha is partially reversed by 2,4–thiazolidinedione
S Kushibiki, K Hodate, H Shingu, Y Ueda, M Shinoda, Y Mori, T Itoh, Y Yokomizo |
Domestic Animal Endocrinology | 2001 |
A pilot study of a thiazolidinedione, troglitazone, in nonalcoholic steatohepatitis
SH Caldwell, EE Hespenheide, JA Redick, JC Iezzoni, EH Battle, BL Sheppard |
The American Journal of Gastroenterology | 2001 |
Enhancing insulin action: From chemical elements to thiazolidinediones
R Perfetti, K Chamie |
Journal of Endocrinological Investigation | 2001 |
Thiazolidinedione treatment prevents free fatty acid-induced insulin resistance in male wistar rats
AL Hevener, D Reichart, A Janez, J Olefsky |
Diabetes | 2001 |
The chlorophyll metabolite phytanic acid is a natural rexinoid – potential for treatment and prevention of diabetes
MF McCarty |
Medical Hypotheses | 2001 |
Pioglitazone Ameliorates Tumor Necrosis Factor- -Induced Insulin Resistance by a Mechanism Independent of Adipogenic Activity of Peroxisome Proliferator-Activated Receptor-
M Iwata, T Haruta, I Usui, Y Takata, A Takano, T Uno, J Kawahara, E Ueno, T Sasaoka, O Ishibashi, M Kobayashi |
Diabetes | 2001 |
Rosiglitazone, Insulin Treatment, and Fasting Correct Defective Activation of Protein Kinase C-ζ/λ by Insulin in Vastus Lateralis Muscles and Adipocytes of Diabetic Rats 1
Y Kanoh, G Bandyopadhyay, MP Sajan, ML Standaert, RV Farese |
Endocrinology | 2001 |
Preferential channeling of energy fuels toward fat rather than muscle during high free fatty acid availability in rats
R Fabris, E Nisoli, A M Lombardi, C Tonello, R Serra, M Granzotto, I Cusin, F Rohner-Jeanrenaud, G Federspil, M O Carruba, R Vettor |
Diabetes | 2001 |
Inhibition of Monocyte Chemoattractant Protein-1 Expression in Cytokine-Treated Human Lung Epithelial Cells by Thiazolidinedione
A Momoi, K Murao, H Imachi, T Ishida, WM Cao, M Sato, J Takahara |
Chest | 2001 |
Tumor necrosis factor-α is induced through phorbol ester- and glycated human albumin-dependent pathway in THP-1 cells
T Naitoh, M Kitahara, N Tsuruzoe |
Cellular Signalling | 2001 |
Rosiglitazone treatment of patients with extreme insulin resistance and diabetes mellitus due to insulin receptor mutations has no effects on glucose and lipid metabolism
H Vestergaard, S Lund, O Pedersen |
Journal of Internal Medicine | 2001 |
Thiazolidinediones (PPARγ agonists) but not PPARα agonists increase IRS-2 gene expression in 3T3-L1 and human adipocytes
U Smith, SI Gogg, A Johansson, T Olausson, VI Rotter, B Svalstedt |
The FASEB Journal | 2001 |
PPAR agonists as direct modulators of the vessel wall in cardiovascular disease
KW Buchan, DG Hassall |
Medicinal Research Reviews | 2000 |
Alteration in Expression Profiles of a Series of Diabetes-Related Genes in db/db Mice Following Treatment With Thiazolidinediones
A Suzuki, T Yasuno, H Kojo, J Hirosumi, S Mutoh, Y Notsu |
The Japanese Journal of Pharmacology | 2000 |
COX-2 and the cyclopentenone prostaglandins - a new chapter in the book of inflammation?
PR Colville-Nash, DW Gilroy |
Prostaglandins & Other Lipid Mediators | 2000 |
Troglitazone Inhibits Mitogenic Signaling by Insulin in Vascular Smooth Muscle Cells
S Goetze, S Kim, XP Xi, K Graf, DC Yang, E Fleck, WP Meehan, WA Hsueh, RE Law |
Journal of Cardiovascular Pharmacology | 2000 |
PPAR-γ agonists: therapeutic role in diabetes, inflammation and cancer
GJ Murphy, JC Holder |
Trends in Pharmacological Sciences | 2000 |
Troglitazone reduces plasma levels of tumour necrosis factor-alpha in obese patients with type 2 diabetes
A Katsuki, Y Sumida, K Murata, M Furuta, R Araki-Sasaki, K Tsuchihashi, Y Hori, Y Yano, EC Gabazza, Y Adachi |
Diabetes, Obesity and Metabolism | 2000 |
Transcriptional control of adipogenesis
SM Rangwala, MA Lazar |
Annual Review of Nutrition | 2000 |
Toward a wholly nutritional therapy for type 2 diabetes
MF McCarty |
Medical Hypotheses | 2000 |
Ligands of peroxisome proliferator-activated receptor γ modulate profibrogenic and proinflammatory actions in hepatic stellate cells
F Marra, E Efsen, RG Romanelli, A Caligiuri, S Pastacaldi, G Batignani, A Bonacchi, R Caporale, G Laffi, M Pinzani, P Gentilini |
Gastroenterology | 2000 |
Down-regulation by troglitazone of hepatic tumor necrosis factor-α and interleukin-6 mRNA expression in a murine model of non-insulin-dependent diabetes∗
S Sigrist, M Bedoucha, UA Boelsterli |
Biochemical Pharmacology | 2000 |
Toward practical prevention of type 2 diabetes
MF McCarty |
Medical Hypotheses | 2000 |
Tumor Necrosis Factor α Inhibits Insulin-induced Mitogenic Signaling in Vascular Smooth Muscle Cells
S Goetze, U Kintscher, H Kawano, Y Kawano, S Wakino, E Fleck, WA Hsueh, RE Law |
The Journal of biological chemistry | 2000 |
Peroxisome Proliferator-activated Receptor α Activators Improve Insulin Sensitivity and Reduce Adiposity
M Guerre-Millo, P Gervois, E Raspé, L Madsen, P Poulain, B Derudas, JM Herbert, DA Winegar, TM Willson, JC Fruchart, RK Berge, B Staels |
The Journal of biological chemistry | 2000 |
Thiazolidinedione Treatment Enhances Insulin Effects on Protein Kinase C-ζ/λ Activation and Glucose Transport in Adipocytes of Nondiabetic and Goto-Kakizaki Type II Diabetic Rats
Y Kanoh, G Bandyopadhyay, MP Sajan, ML Standaert, RV Farese |
The Journal of biological chemistry | 2000 |
Nuovi farmaci per la terapia del diabete di tipo 2
F Santeusanio, G Perriello |
L'Endocrinologo | 2000 |
Obesity: Pathology and Therapy
DH Lockwood, TC Heffner |
2000 | |
The PPARs: From Orphan Receptors to Drug Discovery
TM Willson, PJ Brown, DD Sternbach, BR Henke |
Journal of Medicinal Chemistry | 2000 |
A novel therapy for colitis utilizing PPAR-γ ligands to inhibit the epithelial inflammatory response
CG Su, X Wen, ST Bailey, W Jiang, SM Rangwala, SA Keilbaugh, A Flanigan, S Murthy, MA Lazar, GD Wu |
Journal of Clinical Investigation | 1999 |
The expression of adhesion molecules on endothelial cells is inhibited by troglitazone through its antioxidant activity
L Cominacini, U Garbin, AF Pasini, A Davoli, M Campagnola, A Rigoni, L Tosetti, VL Cascio |
Cell Communication and Adhesion | 1999 |
Tumor necrosis factor-α as a mediator of the insulin resistance of obesity
ED Rosen, BM Spiegelman |
Current Opinion in Endocrinology & Diabetes | 1999 |
Current Views on the Mechanism of Action of Thiazolidinedione Insulin Sensitizers
BJ Goldstein |
Diabetes Technology & Therapeutics | 1999 |
Mechanisms by which Thiazolidinediones Enhance Insulin Action
MJ Reginato, MA Lazar |
Trends in Endocrinology & Metabolism | 1999 |
The Emerging Role of Thiazolidinediones in the Treatment of Diabetes-Mellitus and Related Disorders
S Subramaniam |
Clinical and Experimental Hypertension | 1999 |
Cross-Regulation of C/EBPα and PPARγ Controls the Transcriptional Pathway of Adipogenesis and Insulin Sensitivity
Z Wu, ED Rosen, R Brun, S Hauser, G Adelmant, AE Troy, C McKeon, GJ Darlington, BM Spiegelman |
Molecular Cell | 1999 |
Thiazolidinedione inhibits the production of monocyte chemoattractant protein-1 in cytokine-treated human vascular endothelial cells
K Murao, H Imachi, A Momoi, Y Sayo, H Hosokawa, M Sato, T Ishida, J Takahara |
FEBS Letters | 1999 |
Thiazolidinedione inhibits production of RANTES in a cytokine-treated human lung epithelial cell line
A Momoi, K Murao, H Imachi, Y Sayo, H Nakamura, H Hosokawa, M Sato, J Fujita, H Okada, T Ishida, J Takahara |
FEBS Letters | 1999 |
Thiazolidinediones down-regulate plasminogen activator inhibitor type 1 expression in human vascular endothelial cells: A possible role for PPARgamma in endothelial function
K Kato, H Satoh, Y Endo, D Yamada, S Midorikawa, W Sato, K Mizuno, T Fujita, K Tsukamoto, T Watanabe |
Biochemical and Biophysical Research Communications | 1999 |
Molecular basis of insulin-stimulated GLUT4 vesicle trafficking. Location! Location! Location!
V Ribon, JH Johnson, HS Camp, AR Saltiel |
The Journal of biological chemistry | 1999 |
Peroxisome proliferator-activated receptor-γ: a versatile metabolic regulator
S Rocchi, J Auwerx |
Annals of Medicine | 1999 |
Tumor Necrosis Factor α-induced Pancreatic β-Cell Insulin Resistance Is Mediated by Nitric Oxide and Prevented by 15-Deoxy-Δ 12,14 -prostaglandin J 2 and Aminoguanidine: A ROLE FOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR γ ACTIVATION AND iNOS EXPRESSION
G Kwon, G Xu, CA Marshall, ML McDaniel |
The Journal of biological chemistry | 1999 |
TNF-α–Induced Migration of Vascular Smooth Muscle Cells Is MAPK Dependent
S Goetze, , Y Kawano, H Kawano, E Fleck, WA Hsueh, RE Law |
Hypertension | 1999 |
Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism*
B Desvergne, W Wahli |
Endocrine reviews | 1999 |
Insulin action and insulin resistance: diseases involving defects in insulin receptors, signal transduction, and the glucose transport effector system
S Hunter |
The American Journal of Medicine | 1998 |
Insulin action enhancement normalizes brachial artery vasoactivity in patients with peripheral vascular disease and occult diabetes
R Avena, ME Mitchell, ES Nylen, KM Curry, AN Sidawy |
Journal of Vascular Surgery | 1998 |
Catabolic proinflammatory cytokines
JM Argilés, FJ López-Soriano |
Current Opinion in Clinical Nutrition and Metabolic Care | 1998 |
Transcriptional control of adipogenesis
L Fajas, JC Fruchart, J Auwerx |
Current Opinion in Cell Biology | 1998 |
The nuclear receptor PPARγ-bigger than fat
SA Kliewer, TM Willson |
Current Opinion in Genetics & Development | 1998 |
Insulin Resistance in Cancer Patients Is Associated with Enhanced Tumor Necrosis Factor-α Expression in Skeletal Muscle
Y Noguchi, T Yoshikawa, D Marat, C Doi, T Makino, K Fukuzawa, A Tsuburaya, S Satoh, T Ito, S Mitsuse |
Biochemical and Biophysical Research Communications | 1998 |
A Potent Antidiabetic Thiazolidinedione with Unique Peroxisome Proliferator-activated Receptor γ-activating Properties
MJ Reginato, ST Bailey, SL Krakow, C Minami, S Ishii, H Tanaka, MA Lazar |
The Journal of biological chemistry | 1998 |
Overexpression of Perilipin A and B Blocks the Ability of Tumor Necrosis Factor α to Increase Lipolysis in 3T3-L1 Adipocytes
SC Souza, LM de Vargas, MT Yamamoto, P Lien, MD Franciosa, LG Moss, AS Greenberg |
The Journal of biological chemistry | 1998 |
Transcription-Modulating Drugs: A New Frontier in the Treatment of Essential Hypertension
TW Kurtz, DG Gardner |
Hypertension | 1998 |
Adipose Tissue-Derived Tumor Necrosis Factor Activity Correlates with Fat Cell Size But Not Insulin Action in Aging Rats**This work was supported by National Institutes of Aging Grant KO1-AG00645 (to C.M.) and the National Institutes of Health Grant DK-47416 (to M.P.)
CL Morin, EC Gayles, DA Podolin, Y Wei, M Xu, MJ Pagliassotti |
Endocrinology | 1998 |
The New Antidiabetic Drug MCC-555 Acutely Sensitizes Insulin Signaling in Isolated Cardiomyocytes**This work was supported by the Ministerium für Wissenschaft und Forschung des Landes Nordrhein-Westfalen, the Bundesministerium für Gesundheit, EU COST Action B5, and a grant from Mitsubishi Chemical (Yokohama, Japan)
LS Liu, H Tanaka, S Ishii, J Eckel |
Endocrinology | 1998 |