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E Chaves-Olarte, … , C Eichel-Streiber, M Thelestam
Published October 1, 1997
Citation Information: J Clin Invest. 1997;100(7):1734-1741. https://doi.org/10.1172/JCI119698.
Citation Information: J Clin Invest. 1997;100(7):1734-1741. https://doi.org/10.1172/JCI119698.
Abstract
Research Article
Authors
E Chaves-Olarte, M Weidmann, C Eichel-Streiber, M Thelestam
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Citations to this article (118)
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|
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|
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|
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|
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|
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|
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|
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|
Clostridium difficile
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|
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|
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|
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|
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|
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|
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DE Voth, JD Ballard |
Clinical microbiology reviews | 2005 |
|
Yearbook of Intensive Care and Emergency Medicine 2005
JL Vincent |
2005 | |
|
Antibiotic-associated diarrhoea
L Beaugerie, JC Petit |
Best Practice & Research Clinical Gastroenterology | 2004 |
|
Immunological detection and cytotoxic properties of toxins from toxin A-positive, toxin B-positive Clostridium difficile variants
JE Blake, F Mitsikosta, MA Metcalfe |
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|
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|
Clostridium sordellii Lethal Toxin Is Maintained in a Multimeric Protein Complex
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|
Activation of NF-kappaB and IL-8 by Yersinia enterocolitica invasin protein is conferred by engagement of Rac1 and MAP kinase cascades
GA Grassl, M Kracht, A Wiedemann, E Hoffmann, M Aepfelbacher, C Eichel-Streiber, E Bohn, IB Autenrieth |
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|
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Biochemical Journal | 2003 |
|
The complete receptor-binding domain of Clostridium difficile toxin A is required for endocytosis
C Frisch, R Gerhard, K Aktories, F Hofmann, I Just |
Biochemical and Biophysical Research Communications | 2003 |
|
Expression of recombinant Clostridium difficile toxin A using the Bacillus megaterium system
S Burger, H Tatge, F Hofmann, H Genth, I Just, R Gerhard |
Biochemical and Biophysical Research Communications | 2003 |
|
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J Kumakiri, S Oda, K Kinoshita, S Miyazaki |
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|
Microbial Pathogenesis and the Intestinal Epithelial Cell
GA Hecht |
2003 | |
|
BACTERIALTOXINSTHATMODIFYTHEACTINCYTOSKELETON
JT Barbieri, MJ Riese, K Aktories |
Annual Review of Cell and Developmental Biology | 2002 |
|
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E Chaves-Olarte, E Freer, A Parra, C Guzmán-Verri, E Moreno, M Thelestam |
The Journal of biological chemistry | 2002 |
|
Clostridium difficile toxins disrupt epithelial barrier function by altering membrane microdomain localization of tight junction proteins
A Nusrat, C Eichel-Streiber, JR Turner, P Verkade, JL Madara, CA Parkos |
Infection and immunity | 2001 |
|
The pathogenicity of Clostridium difficile
IR Poxton, J McCoubrey, G Blair |
Clinical Microbiology and Infection | 2001 |
|
Bacterial protein toxins inhibiting low-molecular-mass GTP-binding proteins
I Just, F Hofmann, H Genth, R Gerhard |
International Journal of Medical Microbiology | 2001 |
|
Variant toxin B and a functional toxin A produced byClostridium difficileC34
M Mehlig, M Moos, V Braun, B Kalt, DE Mahony, C Eichel-Streiber |
FEMS Microbiology Letters | 2001 |
|
Microtubule disassembly increases endothelial cell barrier dysfunction: role of MLC phosphorylation
AD Verin, A Birukova, P Wang, F Liu, P Becker, K Birukov, JG Garcia |
American journal of physiology. Lung cellular and molecular physiology | 2001 |
|
p38 MAP kinase activation by Clostridium difficile toxin A mediates monocyte necrosis, IL-8 production, and enteritis
M Warny, AC Keates, S Keates, I Castagliuolo, JK Zacks, S Aboudola, A Qamar, C Pothoulakis, JT LaMont, CP Kelly |
Journal of Clinical Investigation | 2000 |
|
Clostridium difficile Toxin: Cytoskeletal Changes and Lactate Dehydrogenase Release in Hepatocytes
EM Grossmann, WE Longo, DL Kaminski, GS Smith, CE Murphy, RL Durham, MJ Shapiro, JG Norman, JE Mazuski |
Journal of Surgical Research | 2000 |
|
Quantitative determination of ceramide using diglyceride kinase
DK Perry, A Bielawska, YA Hannun |
Methods in enzymology | 2000 |
|
Role of ras-dependent ERK activation in phorbol ester-induced endothelial cell barrier dysfunction
AD Verin, F Liu, N Bogatcheva, T Borbiev, MB Hershenson, P Wang, JG Garcia |
American journal of physiology. Lung cellular and molecular physiology | 2000 |
|
Divergent Roles for Ras and Rap in the Activation of p38 Mitogen-activated Protein Kinase by Interleukin-1
EM Palsson, M Popoff, M Thelestam, LA O'Neill |
The Journal of biological chemistry | 2000 |
|
The p42/p44 MAP Kinase Pathway Prevents Apoptosis Induced by Anchorage and Serum Removal
ML Gall, JC Chambard, JP Breittmayer, D Grall, J Pouysségur, EV Obberghen-Schilling, J Brugge |
Molecular biology of the cell | 2000 |
|
Polymeric IgA Is Superior to Monomeric IgA and IgG Carrying the Same Variable Domain in Preventing Clostridium difficile Toxin A Damaging of T84 Monolayers
H Stubbe, J Berdoz, JP Kraehenbuhl, B Corthésy |
Journal of immunology (Baltimore, Md. : 1950) | 2000 |
|
Rho proteins and the p38-MAPK pathway are important mediators for LPS-induced interleukin-8 expression in human endothelial cells
S Hippenstiel, S Soeth, B Kellas, O Fuhrmann, J Seybold, M Krüll, C v. Eichel-Streiber, M Goebeler, S Ludwig, N Suttorp |
Blood | 2000 |
|
The cytolethal distending toxin from the chancroid bacterium Haemophilus ducreyi induces cell-cycle arrest in the G2 phase
X Cortes-Bratti, E Chaves-Olarte, T Lagergård, M Thelestam |
Journal of Clinical Investigation | 1999 |
|
Small intestinal pathology
C Okolo, C Surawicz |
Current Opinion in Gastroenterology | 1999 |
|
Clostridium difficile infection in children
KL McGowan, HA Kader |
Clinical Microbiology Newsletter | 1999 |
|
A balance of signaling by Rho family small GTPases RhoA, Rac1 and Cdc42 coordinates cytoskeletal morphology but not cell survival
JP Moorman, D Luu, J Wickham, DA Bobak, CS Hahn |
Oncogene | 1999 |
|
A Novel Cytotoxin from Clostridium difficile Serogroup F Is a Functional Hybrid between Two Other Large Clostridial Cytotoxins
E Chaves-Olarte, P Löw, E Freer, T Norlin, M Weidmann, C Eichel-Streiber, M Thelestam |
The Journal of biological chemistry | 1999 |
|
Single toxin detection is inadequate to diagnose Clostridium difficile diarrhea in pediatric patients
HA Kader, DA Piccoli, AF Jawad, KL Mcgowan, ES Maller |
Gastroenterology | 1998 |
|
Rho Protein Inhibition Blocks Protein Kinase C Translocation and Activation
S Hippenstiel, T Kratz, M Krüll, J Seybold, C Eichel-Streiber, N Suttorp |
Biochemical and Biophysical Research Communications | 1998 |
|
Effects of Bacterial Toxins on Small GTP-binding Proteins
E Chaves-Olarte, X Cortes-Bratti, M Thelestam |
Toxicology in Vitro | 1998 |
|
Clostridium difficile Toxins A and B Are Cation-dependent UDP-glucose Hydrolases with Differing Catalytic Activities
WP Ciesla, DA Bobak |
The Journal of biological chemistry | 1998 |
|
NOSOCOMIAL INFECTIONS IN HAND SURGERY
ER Calkins |
Hand Clinics | 1998 |
|
Molecular details of the activation of soluble phospholipase A2 on lipid bilayers. Comparison of computer simulations with experimental results
JD Bell, RL Biltonen |
The Journal of biological chemistry | 1992 |
|
Bacterial Protein Toxins
M Ispolatovskaya |
Bacterial Protein Toxins | 1971 |
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