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P J Sime, … , K G Csaky, J Gauldie
Published August 15, 1997
Citation Information: J Clin Invest. 1997;100(4):768-776. https://doi.org/10.1172/JCI119590.
Citation Information: J Clin Invest. 1997;100(4):768-776. https://doi.org/10.1172/JCI119590.
Abstract
Research Article
Authors
P J Sime, Z Xing, F L Graham, K G Csaky, J Gauldie
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Citations to this article (826)
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Current models of pulmonary fibrosis for future drug discovery efforts
T Yanagihara, SG Chong, M Vierhout, JA Hirota, K Ask, M Kolb |
Expert Opinion on Drug Discovery | 2020 |
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Candidate rejuvenating factor GDF11 and tissue fibrosis: friend or foe?
J Frohlich, M Vinciguerra |
GeroScience | 2020 |
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Transforming growth factor–β in tissue fibrosis
NG Frangogiannis |
Journal of Experimental Medicine | 2020 |
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Repurposing of Kinase Inhibitors for Treatment of COVID-19
E Weisberg, A Parent, PL Yang, M Sattler, Q Liu, Q Liu, J Wang, C Meng, SJ Buhrlage, N Gray, JD Griffin |
Pharmaceutical Research | 2020 |
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Mechanical stretch sustains myofibroblast phenotype and function in microtissues through latent TGF-β1 activation
M Walker, M Godin, AE Pelling |
Integrative biology : quantitative biosciences from nano to macro | 2020 |
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Protein tyrosine phosphatase-α amplifies transforming growth factor-β-dependent profibrotic signaling in lung fibroblasts
Y Aschner, M Nelson, M Brenner, H Roybal, K Beke, C Meador, D Foster, KA Correll, PR Reynolds, K Anderson, EF Redente, J Matsuda, DW Riches, SD Groshong, A Pozzi, J Sap, Q Wang, D Rajshankar, CA McCulloch, RL Zemans, GP Downey |
American journal of physiology. Lung cellular and molecular physiology | 2020 |
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Gastrin-releasing peptide induces fibrotic response in MRC5s and proliferation in A549s
O Kayalar, F Oztay, HG Ongen |
Cell Communication and Signaling | 2020 |
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Del-1, an Endogenous Inhibitor of TGF-β Activation, Attenuates Fibrosis
DY Kim, SH Lee, Y Fu, F Jing, WY Kim, SB Hong, JA Song, H Choe, HJ Ryu, M Kim, D Lim, MS Kim, CO Yun, T Lee, H Hyun, EY Choi |
Frontiers in immunology | 2020 |
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Integrin αvβ6 Positron Emission Tomography Imaging in Lung Cancer Patients Treated With Pulmonary Radiation Therapy
A Saleem, Y Helo, Z Win, R Dale, J Cook, GE Searle, P Wells |
International journal of radiation oncology, biology, physics | 2020 |
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Senescence in Pulmonary Fibrosis: Between Aging and Exposure
A Venosa |
Frontiers in Medicine | 2020 |
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A Novel Fibroblast Reporter Cell Line for in vitro Studies of Pulmonary Fibrosis
J Nemeth, A Schundner, K Quast, VE Winkelmann, M Frick |
Frontiers in physiology | 2020 |
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Human menstrual blood-derived stem cells mitigate bleomycin-induced pulmonary fibrosis through anti-apoptosis and anti-inflammatory effects
X Chen, Y Wu, Y Wang, L Chen, W Zheng, S Zhou, H Xu, Y Li, L Yuan, C Xiang |
Stem Cell Research & Therapy | 2020 |
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The contribution of animal models to understanding the role of the immune system in human idiopathic pulmonary fibrosis
T Miles, GF Hoyne, DA Knight, MW Fear, SE Mutsaers, CM Prêle |
IBMS BoneKEy | 2020 |
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Cardiovascular Complications of Respiratory Disorders
MÁ Martínez-García, JL Pépin, M Cazzola |
2020 | |
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Transplantation of Human Amnion Epithelial Cells Improves Endometrial Regeneration in Rat Model of Intrauterine Adhesions
X Ouyang, S You, Y Zhang, C Zhang, G Zhang, X Shao, F He, L Hu |
Stem Cells and Development | 2020 |
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Crosstalk between pleural mesothelial cell and lung fibroblast contributes to pulmonary fibrosis
F Liu, F Yu, YZ Lu, PP Cheng, LM Liang, M Wang, SJ Chen, Y Huang, LJ Song, XL He, L Xiong, JB Xin, WL Ma, H Ye |
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research | 2020 |
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Regulatory T Cells Limit Pneumococcus-Induced Exacerbation of Lung Fibrosis in Mice
S Moyé, T Bormann, R Maus, T Sparwasser, I Sandrock, I Prinz, G Warnecke, T Welte, J Gauldie, M Kolb, UA Maus |
Journal of immunology (Baltimore, Md. : 1950) | 2020 |
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Myricetin ameliorates bleomycin-induced pulmonary fibrosis in mice by inhibiting TGF-β signaling via targeting HSP90β
X Li, H Yu, L Liang, Z Bi, Y Wang, S Gao, M Wang, H Li, Y Miao, R Deng, L Ma, J Luan, S Li, M Liu, J Lin, H Zhou, C Yang |
Biochemical Pharmacology | 2020 |
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Adelmidrol: A New Promising Antioxidant and Anti-Inflammatory Therapeutic Tool in Pulmonary Fibrosis
R Fusco, M Cordaro, T Genovese, D Impellizzeri, R Siracusa, E Gugliandolo, AF Peritore, R DAmico, R Crupi, S Cuzzocrea, RD Paola |
Antioxidants | 2020 |
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Discovering the genes mediating the interactions between chronic respiratory diseases in the human interactome
E Maiorino, SH Baek, F Guo, X Zhou, PH Kothari, EK Silverman, AL Barabási, ST Weiss, BA Raby, A Sharma |
Nature Communications | 2020 |
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The role of WNT5A and Ror2 in peritoneal membrane injury
M Padwal, L Liu, PJ Margetts |
Journal of Cellular and Molecular Medicine | 2020 |
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Out of Tune: Fibroblasts Turn Fibrotic When They Lack a FENDRR
CF Woeller, MA OReilly |
American journal of respiratory cell and molecular biology | 2020 |
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Enhanced tuberculosis clearance through the combination treatment with recombinant adenovirus-mediated granulysin delivery
L Hao, J Ma, C Shi, X Lin, Y Zhang, BN Jo-Lewis, Q Lei, N Ullah, Z Yao, X Fan |
Theranostics | 2020 |
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Syndecan-1 promotes lung fibrosis by regulating epithelial reprogramming through extracellular vesicles
Tanyalak Parimon, Changfu Yao, David M Habiel, Lingyin Ge, Stephanie Bora, Rena Brauer, Christopher M. Evans, ting xie, Felix Alonso-Valenteen, Dianhua Jiang, Paul W. Noble, Cory M. Hogaboam, Nan Deng, Olivier Burgy, Travis J Antes, Melanie Konigshoff, Barry R. Stripp, Sina Gharib, Peter Chen, Lali Medina-Kauwe |
JCI Insight | 2019 |
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Chitinase 1 regulates pulmonary fibrosis by modulating TGF-β/SMAD7 pathway via TGFBRAP1 and FOXO3
CM Lee, CH He, JW Park, JH Lee, S Kamle, B Ma, B Akosman, R Cotez, E Chen, Y Zhou, EL Herzog, C Ryu, X Peng, IO Rosas, S Poli, CF Bostwick, AM Choi, JA Elias, CG Lee |
Life science alliance | 2019 |
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Genetic evidence for the role of transforming growth factor-β in atopic phenotypes
KA Weissler, PA Frischmeyer-Guerrerio |
Current Opinion in Immunology | 2019 |
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tPA promotes the proliferation of lung fibroblasts and activates the Wnt/β-catenin signaling pathway in idiopathic pulmonary fibrosis
L Chen, J Hou, X Fu, X Chen, J Wu, X Han |
Cell cycle (Georgetown, Tex.) | 2019 |
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Neohesperidin inhibits TGF-β1/Smad3 signaling and alleviates bleomycin-induced pulmonary fibrosis in mice
J Guo, Y Fang, F Jiang, L Li, H Zhou, X Xu, W Ning |
European Journal of Pharmacology | 2019 |
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The Molecular Mechanism of Transforming Growth Factor-β Signaling for Intestinal Fibrosis: A Mini-Review
SM Yun, SH Kim, EH Kim |
Frontiers in pharmacology | 2019 |
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Wedelolactone Attenuates Pulmonary Fibrosis Partly Through Activating AMPK and Regulating Raf-MAPKs Signaling Pathway
J Yang, L Tao, B Liu, X You, C Zhang, H Xie, R Li |
Frontiers in pharmacology | 2019 |
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Effects of PARP-1 Deficiency and Histamine H4 Receptor Inhibition in an Inflammatory Model of Lung Fibrosis in Mice
M Durante, S Sgambellone, C Lanzi, P Nardini, A Pini, F Moroni, E Masini, L Lucarini |
Frontiers in pharmacology | 2019 |
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Kangfuxin Oral Liquid Attenuates Bleomycin-Induced Pulmonary Fibrosis via the TGF- β 1/Smad Pathway
H Yao, S Wei, Y Xiang, Z Wu, W Liu, B Wang, X Li, H Xu, J Zhao, Y Gao |
Evidence-Based Complementary and Alternative Medicine | 2019 |
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YY1 mediates TGF-β1-induced EMT and pro-fibrogenesis in alveolar epithelial cells
C Zhang, X Zhu, Y Hua, Q Zhao, K Wang, L Zhen, G Wang, J Lü, A Luo, WC Cho, X Lin, Z Yu |
Respiratory Research | 2019 |
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Mouse Cell Culture: Methods and Protocols
I Bertoncello |
2019 | |
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Is Progression of Pulmonary Fibrosis due to Ventilation-induced Lung Injury?
RK Albert, B Smith, CE Perlman, DA Schwartz |
American journal of respiratory and critical care medicine | 2019 |
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Na+,K+-ATPase as a Target for Treatment of Tissue Fibrosis
SN Orlov, J La, LV Smolyaninova, NO Dulin |
Current medicinal chemistry | 2019 |
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Loss of cells expressing fibroblast activation protein has variable effects in models of TGF-β and chronic bleomycin-induced fibrosis
T Kimura, J Monslow, A Klampatsa, M Leibowitz, J Sun, M Liousia, P Woodruff, E Moon, L Todd, E Puré, SM Albelda |
American journal of physiology. Lung cellular and molecular physiology | 2019 |
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Experimental pulmonary fibrosis was suppressed by microRNA-506 through NF-kappa-mediated apoptosis and inflammation
M Zhu, Y An, X Zhang, Z Wang, H Duan |
Cell and Tissue Research | 2019 |
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Caveolin-1–derived peptide limits development of pulmonary fibrosis
AS Marudamuthu, YP Bhandary, L Fan, V Radhakrishnan, BA MacKenzie, E Maier, SK Shetty, MR Nagaraja, V Gopu, N Tiwari, Y Zhang, AB Watts, RO Williams, GJ Criner, S Bolla, N Marchetti, S Idell, S Shetty |
Science Translational Medicine | 2019 |
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Curcumin inhibits the TGF-β1-dependent differentiation of lung fibroblasts via PPARγ-driven upregulation of cathepsins B and L
A Saidi, M Kasabova, L Vanderlynden, M Wartenberg, GH Kara-Ali, D Marc, F Lecaille, G Lalmanach |
Scientific Reports | 2019 |
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Mechanical stress-induced mast cell degranulation activates TGF-β1 signalling pathway in pulmonary fibrosis
C Shimbori, C Upagupta, PS Bellaye, EA Ayaub, S Sato, T Yanagihara, Q Zhou, A Ognjanovic, K Ask, J Gauldie, P Forsythe, MR Kolb |
Thorax | 2019 |
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Pathological Study on Epithelial-Mesenchymal Transition in Silicotic Lung Lesions in Rat
M Komai, K Mihira, A Shimada, I Miyamoto, K Ogihara, Y Naya, T Morita, K Inoue, H Takano |
Veterinary Sciences | 2019 |
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Oncostatin M in the Regulation of Connective Tissue Cells and Macrophages in Pulmonary Disease
CD Richards, F Botelho |
Biomedicines | 2019 |
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Ion Channels and Transporters in Diabetic Kidney Disease
Spires D, Manis AD, Staruschenko A |
Current topics in membranes | 2019 |
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Sustained Smad2 Phosphorylation Is Required for Myofibroblast Transformation in Response to TGF-β
S Ard, EB Reed, LV Smolyaninova, SN Orlov, GM Mutlu, RD Guzy, NO Dulin |
American journal of respiratory cell and molecular biology | 2019 |
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Anti-fibrotic effects of tannic acid through regulation of a sustained TGF-beta receptor signaling
EB Reed, S Ard, J La, CY Park, L Culligan, JJ Fredberg, LV Smolyaninova, SN Orlov, B Chen, R Guzy, GM Mutlu, NO Dulin |
Respiratory Research | 2019 |
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Surfactant dysfunction and alveolar collapse are linked with fibrotic septal wall remodeling in the TGF-β1-induced mouse model of pulmonary fibrosis
L Beike, C Wrede, H Jan, E Lopez-Rodriguez, C Kloth, J Gauldie, M Kolb, UA Maus, M Ochs, L Knudsen |
Laboratory Investigation | 2019 |
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Stem Cell-Based Therapy for Lung Disease
JK Burgess, IH Heijink |
2019 | |
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Protective and anti-inflammatory effect of selenium nano-particles against bleomycin-induced pulmonary injury in male rats
R Shahabi, A Anissian, SA Javadmoosavi, F Nasirinezhad |
Drug and Chemical Toxicology | 2019 |
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The FMS-like tyrosine kinase-3 ligand/lung dendritic cell axis contributes to regulation of pulmonary fibrosis
MT Tarrés, F Aschenbrenner, R Maus, J Stolper, L Schuette, L Knudsen, EL Rodriguez, D Jonigk, MP Kühnel, D DeLuca, A Prasse, T Welte, J Gauldie, MR Kolb, UA Maus |
Thorax | 2019 |
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Encapsulation of Mesenchymal Stem Cells in 3D Ovarian Cell Constructs Promotes Stable and Long-Term Hormone Secretion with Improved Physiological Outcomes in a Syngeneic Rat Model
S Sittadjody, KM Enck, A Wells, JJ Yoo, A Atala, JM Saul, EC Opara |
Annals of Biomedical Engineering | 2019 |
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Effect of Keratinocytes on Myofibroblasts in Hypertrophic Scars
JS Lee, JS Kim, JW Lee, KY Choi, JD Yang, BC Cho, EJ Oh, TJ Kim, UH Ko, JH Shin, S Jeon, YJ Lee, HY Chung |
Aesthetic Plastic Surgery | 2019 |
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Laminin Alpha1 is a Genetic Modifier of TGF-beta1-Stimulated Pulmonary Fibrosis
Chang-Min Lee, Soo Jung Cho, Won-Kyung Cho, Jin Wook Park, Jae Hyun Lee, Augustine Choi, Ivan O. Rosas, Ming Zheng, Gary Peltz, Chun Geun Lee, Jack A. Elias |
JCI Insight | 2018 |
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Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis
MG Jones, OG Andriotis, JJ Roberts, K Lunn, VJ Tear, L Cao, K Ask, DE Smart, A Bonfanti, P Johnson, A Alzetani, F Conforti, R Doherty, CY Lai, B Johnson, KN Bourdakos, SV Fletcher, BG Marshall, S Jogai, CJ Brereton, SJ Chee, CH Ottensmeier, P Sime, J Gauldie, M Kolb, S Mahajan, A Fabre, A Bhaskar, W Jarolimek, L Richeldi, KM O'Reilly, PD Monk, PJ Thurner, DE Davies |
eLife | 2018 |
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Modeling Idiopathic Pulmonary Fibrosis in Humanized Severe Combined Immunodeficiency Mice
DM Habiel, MS Espindola, AL Coelho, CM Hogaboam |
The American Journal of Pathology | 2018 |
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Reducing protein oxidation reverses lung fibrosis
V Anathy, KG Lahue, DG Chapman, SB Chia, DT Casey, R Aboushousha, JL van der Velden, E Elko, SM Hoffman, DH McMillan, JT Jones, JD Nolin, S Abdalla, R Schneider, DJ Seward, EC Roberson, MD Liptak, ME Cousins, KJ Butnor, DJ Taatjes, RC Budd, CG Irvin, YS Ho, R Hakem, KK Brown, R Matsui, MM Bachschmid, JL Gomez, N Kaminski, A van der Vliet, YM Janssen-Heininger |
Nature Medicine | 2018 |
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Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence
L Vera-Ramirez, SK Vodnala, R Nini, KW Hunter, JE Green |
Nature Communications | 2018 |
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Idiopathic pulmonary fibrosis: Epithelial-mesenchymal interactions and emerging therapeutic targets
JC Hewlett, JA Kropski, TS Blackwell |
Matrix biology : journal of the International Society for Matrix Biology | 2018 |
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Lung Innate Immunity and Inflammation
S Alper, WJ Janssen |
2018 | |
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Lung Innate Immunity and Inflammation
S Alper, WJ Janssen |
2018 | |
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Lung Innate Immunity and Inflammation
S Alper, WJ Janssen |
2018 | |
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Use of animal models in IPF research
R Carrington, S Jordan, SC Pitchford, CP Page |
Pulmonary Pharmacology & Therapeutics | 2018 |
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Interplay between EZH2 and G9a Regulates CXCL10 Gene Repression in Idiopathic Pulmonary Fibrosis
WR Coward, OJ Brand, A Pasini, G Jenkins, AJ Knox, L Pang |
American journal of respiratory cell and molecular biology | 2018 |
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Regulation of Transforming Growth Factor-β/Smad-mediated Epithelial-Mesenchymal Transition by Celastrol Provides Protection against Bleomycin-induced Pulmonary Fibrosis
T Divya, B Velavan, G Sudhandiran |
Basic & Clinical Pharmacology & Toxicology | 2018 |
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MK2 Inhibition Attenuates Fibroblast Invasion and Severe Lung Fibrosis
J Liang, N Liu, X Liu, JM Mena, T Xie, Y Geng, C Huan, Y Zhang, F Taghavifar, G Huang, A Kurkciyan, V Barron, D Jiang, PW Noble |
American journal of respiratory cell and molecular biology | 2018 |
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Matrix abnormalities in pulmonary fibrosis
C Upagupta, C Shimbori, R Alsilmi, M Kolb |
European Respiratory Review | 2018 |
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The Role of TGF-β Signaling in Lung Cancer Associated with Idiopathic Pulmonary Fibrosis
A Saito, M Horie, P Micke, T Nagase |
International journal of molecular sciences | 2018 |
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TGF beta inhibits HGF, FGF7, and FGF10 expression in normal and IPF lung fibroblasts
KA Correll, KE Edeen, EF Redente, RL Zemans, BL Edelman, T Danhorn, D Curran-Everett, A Mikels-Vigdal, RJ Mason |
Physiological Reports | 2018 |
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Subacute TGFβ expression drives inflammation, goblet cell hyperplasia, and pulmonary function abnormalities in mice with effects dependent on CFTR function
EL Kramer, WD Hardie, SK Madala, C Davidson, JP Clancy |
American journal of physiology. Lung cellular and molecular physiology | 2018 |
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Synergistic role of HSP90α and HSP90β to promote myofibroblast persistence in lung fibrosis
PS Bellaye, C Shimbori, T Yanagihara, DA Carlson, P Hughes, C Upagupta, S Sato, N Wheildon, T Haystead, K Ask, M Kolb |
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology | 2018 |
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A hypothetical pathogenesis model for androgenic alopecia: Clarifying the dihydrotestosterone paradox and rate-limiting recovery factors
RS English |
Medical Hypotheses | 2018 |
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DHEA-induced ovarian hyperfibrosis is mediated by TGF-β signaling pathway
D Wang, W Wang, Q Liang, X He, Y Xia, S Shen, H Wang, Q Gao, Y Wang |
Journal of Ovarian Research | 2018 |
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Casein Kinase 1δ/ε Inhibitor, PF670462 Attenuates the Fibrogenic Effects of Transforming Growth Factor-β in Pulmonary Fibrosis
CR Keenan, SY Langenbach, F Jativa, T Harris, M Li, Q Chen, Y Xia, B Gao, MJ Schuliga, J Jaffar, D Prodanovic, Y Tu, A Berhan, PV Lee, GP Westall, AG Stewart |
Frontiers in pharmacology | 2018 |
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Molecular changes during TGF β -mediated lung fibroblast-myofibroblast differentiation: implication for glucocorticoid resistance
JD Breton, D Heydet, LM Starrs, T Veldre, R Ghildyal |
Physiological Reports | 2018 |
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Targeting TGFβ Signaling to Address Fibrosis Using Antisense Oligonucleotides
J March, G Golshirazi, V Cernisova, H Carr, Y Leong, N Lu-Nguyen, L Popplewell |
Biomedicines | 2018 |
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WNT signaling is required for peritoneal membrane angiogenesis
M Padwal, G Cheng, L Liu, F Boivin, AS Gangji, KS Brimble, D Bridgewater, PJ Margetts |
American journal of physiology. Renal physiology | 2018 |
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Prevention and treatment of bleomycin-induced pulmonary fibrosis with the lactate dehydrogenase inhibitor gossypol
JL Judge, DJ Nagel, KM Owens, A Rackow, RP Phipps, PJ Sime, RM Kottmann, B Ryffel |
PloS one | 2018 |
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A Profibrotic Phenotype in Naïve and in Fibrotic Lung Myofibroblasts Is Governed by Modulations in Thy-1 Expression and Activation
PY Cohen, R Breuer, SB Wallach-Dayan |
Mediators of Inflammation | 2018 |
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Mechanisms of Dysfunction in the Aging Vasculature and Role in Age-Related Disease
AJ Donato, DR Machin, LA Lesniewski |
Circulation research | 2018 |
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Modeling radiation-induced lung injury: lessons learned from whole thorax irradiation
TA Beach, AM Groves, JP Williams, JN Finkelstein |
International Journal of Radiation Biology | 2018 |
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Innate lymphoid cells in organ fibrosis
Y Mikami, Y Takada, Y Hagihara, T Kanai |
Cytokine & Growth Factor Reviews | 2018 |
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Synthesis and discovery of a drug candidate for treatment of idiopathic pulmonary fibrosis through inhibition of TGF-β1 pathway
X Li, C Lu, S Liu, shuaishuai Liu, C Su, T Xiao, Z Bi, P Sheng, M Huang, X Liu, Y Wei, L Zhao, S Miao, J Mao, K Huang, S Gao, N Liu, M Qi, T Liu, S Qin, L Wei, T Sun, W Ning, G Yang, H Zhou, C Yang |
European Journal of Medicinal Chemistry | 2018 |
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Ventral hernia repair in rat using nanofibrous polylactic acid/polypropylene meshes
Y Xiaolong, H Xiaoyan, W Bo, H Jianglong, Y Xiaofeng, T Xiao, Z Zongheng, L Linbo, Z Zefeng, W Hongbo |
Nanomedicine | 2018 |
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Fibrosis in Disease: An Organ-Based Guide to Disease Pathophysiology and Therapeutic Considerations
MS Willis, CC Yates, JC Schisler |
2018 | |
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MicroRNA‑326 inhibits endometrial fibrosis by regulating TGF‑β1/Smad3 pathway in intrauterine adhesions
J Ning, H Zhang, H Yang |
Molecular medicine reports | 2018 |
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Protective effect of cysteinyl leukotriene receptor antagonist montelukast in bleomycin-induced pulmonary fibrosis
N Topaloğlu |
Turkish Journal of Thoracic and Cardiovascular Surgery | 2018 |
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Inhibition of Profibrotic Smad3 Action by Cell Penetrating Peptides
Jeong-Han Kang, Mi-Yeon Jung, Xueqian Yin, Mahefatiana Andrianifahanana, Danielle Hernandez, Edward B. Leof |
Journal of Clinical Investigation | 2017 |
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Exploring Animal Models That Resemble Idiopathic Pulmonary Fibrosis
J Tashiro, GA Rubio, AH Limper, K Williams, SJ Elliot, I Ninou, V Aidinis, A Tzouvelekis, MK Glassberg |
Frontiers in Medicine | 2017 |
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Thermodynamic Aspects and Reprogramming Cellular Energy Metabolism during the Fibrosis Process
A Vallée, Y Lecarpentier, JN Vallée |
International journal of molecular sciences | 2017 |
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TGF-β1 Signaling and Tissue Fibrosis
KK Kim, D Sheppard, HA Chapman |
Cold Spring Harbor perspectives in biology | 2017 |
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Osteopontin enhances multi-walled carbon nanotube-triggered lung fibrosis by promoting TGF-β1 activation and myofibroblast differentiation
J Dong, Q Ma |
Particle and Fibre Toxicology | 2017 |
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TGF-β-Induced Endothelial-Mesenchymal Transition in Fibrotic Diseases
E Pardali, G Sanchez-Duffhues, M Gomez-Puerto, P Dijke |
International journal of molecular sciences | 2017 |
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MicroRNA-101 attenuates pulmonary fibrosis by inhibiting fibroblast proliferation and activation
C Huang, X Xiao, Y Yang, A Mishra, Y Liang, X Zeng, X Yang, D Xu, MR Blackburn, CA Henke, L Liu |
The Journal of biological chemistry | 2017 |
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Focal Adhesion Kinase Regulates Hepatic Stellate Cell Activation and Liver Fibrosis
XK Zhao, L Yu, ML Cheng, P Che, YY Lu, Q Zhang, M Mu, H Li, LL Zhu, JJ Zhu, M Hu, P Li, YD Liang, XH Luo, YJ Cheng, ZX Xu, Q Ding |
Scientific Reports | 2017 |
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Targeting TGF-β Mediated SMAD Signaling for the Prevention of Fibrosis
KL Walton, KE Johnson, CA Harrison |
Frontiers in pharmacology | 2017 |
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Innate Immune Cytokines, Fibroblast Phenotypes, and Regulation of Extracellular Matrix in Lung
CD Richards |
Journal of Interferon & Cytokine Research | 2017 |
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An Official American Thoracic Society Workshop Report: Translational Research in Rare Respiratory Diseases
AS Kristof, BJ Petrof, Q Hamid, M Kolb, JS Landry, A MacKenzie, FX McCormack, IJ Murawski, J Moss, F Rauch, IO Rosas, AJ Shapiro, BM Smith, DY Thomas, BC Trapnell, LR Young, MA Zariwala |
Annals of the American Thoracic Society | 2017 |
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Differing Expression of Cytokines and Tumor Markers in Combined Pulmonary Fibrosis and Emphysema compared to Emphysema and Pulmonary Fibrosis
L Xu, W Bian, X Gu, C Shen |
COPD | 2017 |
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Pre-clinical Disease Models in Drug Toxicity Evaluation
ML Foster |
Current Opinion in Toxicology | 2017 |
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Adiponectin is an endogenous anti-fibrotic mediator and therapeutic target
RG Marangoni, Y Masui, F Fang, B Korman, G Lord, J Lee, K Lakota, J Wei, PE Scherer, L Otvos, T Yamauchi, N Kubota, T Kadowaki, Y Asano, S Sato, WG Tourtellotte, J Varga |
Scientific Reports | 2017 |
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The Lactate Dehydrogenase Inhibitor Gossypol Inhibits Radiation-Induced Pulmonary Fibrosis
JL Judge, SH Lacy, WY Ku, KM Owens, E Hernady, TH Thatcher, JP Williams, RP Phipps, PJ Sime, RM Kottmann |
Radiation Research | 2017 |
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The role of epidermal growth factor receptor (EGFR) signaling in SARS coronavirus-induced pulmonary fibrosis
T Venkataraman, MB Frieman |
Antiviral Research | 2017 |
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TIAM1 inhibits lung fibroblast differentiation in pulmonary fibrosis
Z Huang, S Sun, C Yang, J Zheng, Y Nan, R Zhao, Z Lang, H Li, L Ma |
Experimental and therapeutic medicine | 2017 |
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Reduced expression of BMP3 contributes to the development of pulmonary fibrosis and predicts the unfavorable prognosis in IIP patients
X Yu, P Gu, Z Huang, X Fang, Y Jiang, Q Luo, X Li, X Zhu, M Zhan, J Wang, L Fan, R Chen, J Yu, Y Gu, A Liang, X Yi |
Oncotarget | 2017 |
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Epithelial-mesenchymal transition, a spectrum of states: Role in lung development, homeostasis, and disease: Emt in Lung Development, Homeostasis, and Disease
MK Jolly, C Ward, MS Eapen, S Myers, O Hallgren, H Levine, SS Sohal |
Developmental Dynamics | 2017 |
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Induced pluripotent stem cell-conditioned medium suppresses pulmonary fibroblast-to-myofibroblast differentiation via the inhibition of TGF-β1/Smad pathway
Y Zhou, Q Zhang, Y Gao, M Tan, R Zheng, L Zhao, X Zhang |
International journal of molecular medicine | 2017 |
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AKT2 Regulates Pulmonary Inflammation and Fibrosis via Modulating Macrophage Activation
Y Nie, L Sun, Y Wu, Y Yang, J Wang, H He, Y Hu, Y Chang, Q Liang, J Zhu, RD Ye, JW Christman, F Qian |
Journal of immunology (Baltimore, Md. : 1950) | 2017 |
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Attenuation of Bleomycin-Induced Pulmonary Fibrosis in Rats with S-Allyl Cysteine
T Tsukioka, S Takemura, Y Minamiyama, S Mizuguchi, M Toda, S Okada |
Molecules (Basel, Switzerland) | 2017 |
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Prognostic significance of Glasgow prognostic score in patients with acute exacerbation of idiopathic pulmonary fibrosis: Glasgow prognostic score and IPF-AE
HS Kang, KW Cho, SS Kwon, YH Kim |
Respirology (Carlton, Vic.) | 2017 |
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Modulation of CD11c+ lung dendritic cells in respect to TGF-β in experimental pulmonary fibrosis: Modulation of lung DCs in pulmonary fibrosis
K Chakraborty, S Chatterjee, A Bhattacharyya |
Cell Biology International | 2017 |
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An orally active geranyl acetophenone attenuates airway remodeling in a murine model of chronic asthma
YZ Lee, K Shaari, MS Cheema, CL Tham, MR Sulaiman, DA Israf |
European Journal of Pharmacology | 2017 |
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Attenuation of lung fibrosis in mice with clinically-relevant GSTP inhibitor
David McMillan, Jos van der Velden, Karolyn Lahue, Xi Qian, Robert Schneider, Martina Iberg, James Nolin, Sarah Abdalla, Dylan Casey, Kenneth Tew, Danyelle Townsend, Colin Henderson, C Roland Wolf, Kelly Butnor, Douglas Taatjes, Ralph C Budd, Charles Irvin, Albert van der Vliet, Stevenson Flemer, Vikas Anathy, Yvonne Janssen-Heininger |
JCI Insight | 2016 |
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miR-323a-3p regulates lung fibrosis by targeting multiple pro-fibrotic pathways
Lingyin Ge, David Habiel, Philip Hansbro, Richard Kim, Sina Gharib, Jeff Edelman, Melanie Konigshoff, Tanyalak Parimon, Rena Brauer, Ying Huang, Jenieke Allen, Dianhua Jiang, Adrianne Kurkciyan, Takako Mizuno, Barry R. Stripp, Paul W. Noble, Cory M. Hogaboam, Peter Chen |
JCI Insight | 2016 |
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BRD4 mediates NF-κB-dependent epithelial-mesenchymal transition and pulmonary fibrosis via transcriptional elongation
B Tian, Y Zhao, H Sun, Y Zhang, J Yang, AR Brasier |
American journal of physiology. Lung cellular and molecular physiology | 2016 |
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Endoplasmic reticulum stress enhances fibrosis through IRE1α‐mediated degradation of miR‐150 and XBP‐1 splicing
F Heindryckx, F Binet, M Ponticos, K Rombouts, J Lau, J Kreuger, P Gerwins |
EMBO Molecular Medicine | 2016 |
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Myofibroblasts and lung fibrosis induced by carbon nanotube exposure
J Dong, Q Ma |
Particle and Fibre Toxicology | 2016 |
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Inhibition of Plasminogen Activator Inhibitor-1 Attenuates Transforming Growth Factor-β-Dependent Epithelial Mesenchymal Transition and Differentiation of Fibroblasts to Myofibroblasts
K Omori, N Hattori, T Senoo, Y Takayama, T Masuda, T Nakashima, H Iwamoto, K Fujitaka, H Hamada, N Kohno, O Eickelberg |
PloS one | 2016 |
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Neuronal Wiskott-Aldrich syndrome protein regulates TGF- 1-mediated lung vascular permeability
BM Wagener, M Hu, A Zheng, X Zhao, P Che, A Brandon, N Anjum, S Snapper, J Creighton, JL Guan, Q Han, GQ Cai, X Han, JF Pittet, Q Ding |
The FASEB Journal | 2016 |
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Loss of epithelial Gq and G11 signaling inhibits TGF production but promotes IL-33-mediated macrophage polarization and emphysema
AE John, MR Wilson, A Habgood, J Porte, AL Tatler, A Stavrou, G Miele, L Jolly, AJ Knox, M Takata, S Offermanns, RG Jenkins |
Science signaling | 2016 |
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Matrix Remodeling in Pulmonary Fibrosis and Emphysema
T Kulkarni, P OReilly, VB Antony, A Gaggar, VJ Thannickal |
American journal of respiratory cell and molecular biology | 2016 |
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Deglycosylated bleomycin has the antitumor activity of bleomycin without pulmonary toxicity
O Burgy, G Wettstein, PS Bellaye, N Decologne, C Racoeur, F Goirand, G Beltramo, JF Hernandez, A Kenani, P Camus, A Bettaieb, C Garrido, P Bonniaud |
Science Translational Medicine | 2016 |
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TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology
M Morikawa, R Derynck, K Miyazono |
Cold Spring Harbor perspectives in biology | 2016 |
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Hydroxysafflor Yellow A Attenuates Bleomycin-induced Pulmonary Fibrosis in Mice: Hydroxysafflor Yellow A Attenuates Pulmonary Fibrosis
M Jin, Y Wu, L Wang, B Zang, L Tan |
Phytotherapy Research | 2016 |
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Transforming Growth Factor β1 (TGF-β1) Activates Hepcidin mRNA Expression in Hepatocytes
S Chen, T Feng, MV Spasić, S Altamura, K Breitkopf-Heinlein, J Altenöder, TS Weiss, S Dooley, MU Muckenthaler |
The Journal of biological chemistry | 2016 |
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Toll-like Receptor 9 Signaling Is Augmented in Systemic Sclerosis and Elicits Transforming Growth Factor β-Dependent Fibroblast Activation: TLR9 SIGNALING PROMOTES FIBROTIC RESPONSES
F Fang, RG Marangoni, X Zhou, Y Yang, B Ye, A Shangguang, W Qin, W Wang, S Bhattacharyya, J Wei, WG Tourtellotte, J Varga |
Arthritis & Rheumatology | 2016 |
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Identification of P-Rex1 as an anti-inflammatory and anti-fibrogenic target for pulmonary fibrosis
Q Liang, N Cheng, G Zhang, Y Liang, F Qian, D Wu, RD Ye |
Scientific Reports | 2016 |
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αvβ1 integrin as a novel therapeutic target for tissue fibrosis
KH Song, SJ Cho, JY Song |
Annals of translational medicine | 2016 |
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Metformin attenuates lung fibrosis development via NOX4 suppression
N Sato, N Takasaka, M Yoshida, K Tsubouchi, S Minagawa, J Araya, N Saito, Y Fujita, Y Kurita, K Kobayashi, S Ito, H Hara, T Kadota, H Yanagisawa, M Hashimoto, H Utsumi, H Wakui, J Kojima, T Numata, Y Kaneko, M Odaka, T Morikawa, K Nakayama, H Kohrogi, K Kuwano |
Respiratory Research | 2016 |
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Transforming Growth Factor-β: Master Regulator of the Respiratory System in Health and Disease
Y Aschner, GP Downey |
American journal of respiratory cell and molecular biology | 2016 |
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Regulation of transforming growth factor-beta1 (TGF-β1)-induced pro-fibrotic activities by circadian clock gene BMAL1
C Dong, R Gongora, ML Sosulski, F Luo, CG Sanchez |
Respiratory Research | 2016 |
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Contribution of Fetal, but Not Adult, Pulmonary Mesothelium to Mesenchymal Lineages in Lung Homeostasis and Fibrosis
A Gise, SM Stevens, LB Honor, JH Oh, C Gao, B Zhou, WT Pu |
American journal of respiratory cell and molecular biology | 2016 |
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MicroRNA-27a-3p Is a Negative Regulator of Lung Fibrosis by Targeting Myofibroblast Differentiation
H Cui, S Banerjee, N Xie, J Ge, RM Liu, S Matalon, VJ Thannickal, G Liu |
American journal of respiratory cell and molecular biology | 2016 |
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Pirfenidone Initiates a New Era in the Treatment of Idiopathic Pulmonary Fibrosis
AS Selvaggio, PW Noble |
Annual Review of Medicine | 2016 |
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Regulation of myofibroblast differentiation by cardiac glycosides
J La, EB Reed, S Koltsova, O Akimova, RB Hamanaka, GM Mutlu, SN Orlov, NO Dulin |
American journal of physiology. Lung cellular and molecular physiology | 2016 |
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Matrix metalloproteinase 9 is associated with peritoneal membrane solute transport and induces angiogenesis through β-catenin signaling
M Padwal, I Siddique, L Wu, K Tang, F Boivin, L Liu, J Robertson, D Bridgewater, J West-Mays, A Gangji, KS Brimble, PJ Margetts |
Nephrology Dialysis Transplantation | 2016 |
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Ultramicronized palmitoylethanolamide (PEA-um®) in the treatment of idiopathic pulmonary fibrosis
RD Paola, D Impellizzeri, R Fusco, M Cordaro, R Siracusa, R Crupi, E Esposito, S Cuzzocrea |
Pharmacological Research | 2016 |
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Impact of Olmesartan Medoxomil on Amiodarone-Induced Pulmonary Toxicity in Rats: Focus on Transforming Growth Factor-ß1
AA El-Din, OM Allah |
Basic & Clinical Pharmacology & Toxicology | 2016 |
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Adiponectin-derived active peptide ADP355 exerts anti-inflammatory and anti-fibrotic activities in thioacetamide-induced liver injury
H Wang, H Zhang, Z Zhang, B Huang, X Cheng, D Wang, Z Gahu, Z Xue, Y Da, D Li, Z Yao, F Gao, A Xu, R Zhang |
Scientific Reports | 2016 |
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MAP3K19 Is a Novel Regulator of TGF-β Signaling That Impacts Bleomycin-Induced Lung Injury and Pulmonary Fibrosis
SA Boehme, K Franz-Bacon, DN DiTirro, TW Ly, KB Bacon, W Shi |
PloS one | 2016 |
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Self-assembled Micelle Interfering RNA for Effective and Safe Targeting of Dysregulated Genes in Pulmonary Fibrosis
PO Yoon, JW Park, CM Lee, SH Kim, HN Kim, Y Ko, SJ Bae, S Yun, JH Park, T Kwon, WS Kim, J Lee, Q Lu, HR Kang, WK Cho, JA Elias, JS Yang, HO Park, K Lee, CG Lee |
The Journal of biological chemistry | 2016 |
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Targeting of Proteoglycan Synthesis Pathway: A New Strategy to Counteract Excessive Matrix Proteoglycan Deposition and Transforming Growth Factor-β1-Induced Fibrotic Phenotype in Lung Fibroblasts
I Shaukat, L Barré, N Venkatesan, D Li, JC Jaquinet, S Fournel-Gigleux, M Ouzzine, Y Zhou |
PloS one | 2016 |
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Fibroblast growth factor-1 attenuates TGF-β1-induced lung fibrosis: Effect of fibroblast growth factor-1 on pulmonary fibrosis
C Shimbori, PS Bellaye, J Xia, J Gauldie, K Ask, C Ramos, C Becerril, A Pardo, M Selman, M Kolb |
The Journal of Pathology | 2016 |
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Effect of adenovirus-mediated TGF-β1 gene transfer on the function of rabbit articular chondrocytes
Y Tang, J Xiao, Y Wang, M Li, Z Shi |
Journal of Orthopaedic Science | 2016 |
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Polymeric Biomaterials for Tissue Regeneration
J Deng, C Gao |
Polymeric Biomaterials for Tissue Regeneration | 2016 |
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Tissue remodelling in pulmonary fibrosis
L Knudsen, C Ruppert, M Ochs |
Cell and Tissue Research | 2016 |
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SIRT3 blocks myofibroblast differentiation and pulmonary fibrosis by preventing mitochondrial DNA damage
S Bindu, VB Pillai, A Kanwal, S Samant, GM Mutlu, E Verdin, N Dulin, MP Gupta |
American journal of physiology. Lung cellular and molecular physiology | 2016 |
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Assay to Evaluate BAL Fluid Regulation of Fibroblast a-SMA Expression
J Larson-Casey, AB Carter |
Bio-protocol | 2016 |
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Surfactant dysfunction during overexpression of TGF-β1 precedes profibrotic lung remodeling in vivo
E Lopez-Rodriguez, C Boden, M Echaide, J Perez-Gil, M Kolb, J Gauldie, UA Maus, M Ochs, L Knudsen |
American journal of physiology. Lung cellular and molecular physiology | 2016 |
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Haploinsufficiency of the folliculin gene leads to impaired functions of lung fibroblasts in patients with Birt–Hogg–Dubé syndrome
Y Hoshika, F Takahashi, S Togo, M Hashimoto, T Nara, T Kobayashi, F Nurwidya, H Kataoka, M Kurihara, E Kobayashi, H Ebana, M Kikkawa, K Ando, K Nishino, O Hino, K Takahashi, K Seyama |
Physiological Reports | 2016 |
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HYDAMTIQ, a selective PARP-1 inhibitor, improves bleomycin-induced lung fibrosis by dampening the TGF-β/SMAD signalling pathway
L Lucarini, M Durante, C Lanzi, A Pini, G Boccalini, L Calosi, F Moroni, E Masini, G Mannaioni |
Journal of Cellular and Molecular Medicine | 2016 |
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MicroRNA-29c regulates apoptosis sensitivity via modulation of the cell-surface death receptor, Fas, in lung fibroblasts
S Matsushima, J Ishiyama |
American journal of physiology. Lung cellular and molecular physiology | 2016 |
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Drug Discovery and Evaluation: Pharmacological Assays
FJ Hock |
2016 | |
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Advances in Geroscience
F Sierra, R Kohanski |
2016 | |
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Blocking follistatin-like 1 attenuates bleomycin-induced pulmonary fibrosis in mice
Y Dong, Y Geng, L Li, X Li, X Yan, Y Fang, X Li, S Dong, X Liu, X Li, X Yang, X Zheng, T Xie, J Liang, H Dai, X Liu, Z Yin, PW Noble, D Jiang, W Ning |
Journal of Experimental Medicine | 2015 |
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Streptococcus pneumoniae triggers progression of pulmonary fibrosis through pneumolysin
S Knippenberg, B Ueberberg, R Maus, J Bohling, N Ding, MT Tarres, HG Hoymann, D Jonigk, N Izykowski, JC Paton, AD Ogunniyi, S Lindig, M Bauer, T Welte, W Seeger, A Guenther, TH Sisson, J Gauldie, M Kolb, UA Maus |
Thorax | 2015 |
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Reciprocal regulation of TGF-β and reactive oxygen species: a perverse cycle for fibrosis
RM Liu, LP Desai |
Redox Biology | 2015 |
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The Role of TGF-β in the Association Between Primary Graft Dysfunction and Bronchiolitis Obliterans Syndrome: TGF-β in the Association Between PGD and BOS
A DerHovanessian, SS Weigt, V Palchevskiy, MY Shino, DM Sayah, AL Gregson, PW Noble, SM Palmer, MC Fishbein, BM Kubak, A Ardehali, DJ Ross, R Saggar, JP Lynch, RM Elashoff, JA Belperio |
American Journal of Transplantation | 2015 |
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Interleukin-1 as a Common Denominator from Autoinflammatory to Autoimmune Disorders: Premises, Perils, and Perspectives
G Lopalco, L Cantarini, A Vitale, F Iannone, MG Anelli, L Andreozzi, G Lapadula, M Galeazzi, D Rigante |
Mediators of Inflammation | 2015 |
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Advances in mechanisms and signaling pathways of carbon nanotube toxicity
J Dong, Q Ma |
Nanotoxicology | 2015 |
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Increased Expression of TGF-β Signaling Components in a Mouse Model of Fibrosis Induced by Submandibular Gland Duct Ligation
LT Woods, JM Camden, FG El-Sayed, MG Khalafalla, MJ Petris, L Erb, GA Weisman, TV Kalin |
PloS one | 2015 |
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Inflammation induced loss of skeletal muscle
P Londhe, DC Guttridge |
Bone | 2015 |
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Riboswitch-mediated Attenuation of Transgene Cytotoxicity Increases Adeno-associated Virus Vector Yields in HEK-293 Cells
B Strobel, B Klauser, JS Hartig, T Lamla, F Gantner, S Kreuz |
Molecular Therapy | 2015 |
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Methylation-mediated BMPER expression in fibroblast activation in vitro and lung fibrosis in mice in vivo
C Huan, T Yang, J Liang, T Xie, L Cheng, N Liu, A Kurkciyan, JM Mena, C Wang, H Dai, PW Noble, D Jiang |
Scientific Reports | 2015 |
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Cellular crosstalk mechanism of Toll-like receptors in gingival overgrowth (Review)
T Subramani, V Rathnavelu, N Alitheen, P Padmanabhan |
International journal of molecular medicine | 2015 |
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Modulation of pulmonary fibrosis by IL-13Rα2
RV Lumsden, JC Worrell, D Boylan, SM Walsh, J Cramton, I Counihan, S O'Beirne, MF Medina, J Gauldie, A Fabre, SC Donnelly, R Kane, MP Keane |
American journal of physiology. Lung cellular and molecular physiology | 2015 |
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Hirsutella sinensis mycelium attenuates bleomycin-induced pulmonary inflammation and fibrosis in vivo
TT Huang, HC Lai, YF Ko, DM Ojcius, YW Lan, J Martel, JD Young, KY Chong |
Scientific Reports | 2015 |
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Coagulation and anticoagulation in idiopathic pulmonary fibrosis
MG Crooks, SP Hart |
European Respiratory Review | 2015 |
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Fibrosis in the lens. Sprouty regulation of TGFβ-signaling prevents lens EMT leading to cataract
FJ Lovicu, EH Shin, JW McAvoy |
Experimental Eye Research | 2015 |
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MicroRNA-144 dysregulates the transforming growth factor-β signaling cascade and contributes to the development of bronchiolitis obliterans syndrome after human lung transplantation
Z Xu, S Ramachandran, M Gunasekaran, F Zhou, E Trulock, D Kreisel, R Hachem, T Mohanakumar |
The Journal of Heart and Lung Transplantation | 2015 |
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Hippo and TGF-β interplay in the lung field
A Saito, T Nagase |
American journal of physiology. Lung cellular and molecular physiology | 2015 |
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The extracellular matrix and transforming growth factor-β1: Tale of a strained relationship
B Hinz |
Matrix Biology | 2015 |
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Development of Novel Agents for Idiopathic Pulmonary Fibrosis
TG O'Riordan, V Smith, G Raghu |
Chest | 2015 |
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Enhanced endogenous bone morphogenetic protein signaling protects against bleomycin induced pulmonary fibrosis
ED Langhe, F Cailotto, VD Vooght, C Aznar-Lopez, JA Vanoirbeek, FP Luyten, RJ Lories |
Respiratory Research | 2015 |
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Role of eukaryotic translation initiation factor 3a in bleomycin-induced pulmonary fibrosis
XW Li, YH Wu, XH Li, D Li, J Du, CP Hu, YJ Li |
European Journal of Pharmacology | 2015 |
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SMAD-Independent Down-Regulation of Caveolin-1 by TGF-β: Effects on Proliferation and Survival of Myofibroblasts
YY Sanders, Z Cui, CJ le Saux, JC Horowitz, S Rangarajan, A Kurundkar, VB Antony, VJ Thannickal, R Johnson |
PloS one | 2015 |
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Inhibitory effect of l-mimosine on bleomycin-induced pulmonary fibrosis in rats: Role of eIF3a and p27
XW Li, CP Hu, YJ Li, YX Gao, XM Wang, JR Yang |
International Immunopharmacology | 2015 |
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Structural and functional correlations in a large animal model of bleomycin-induced pulmonary fibrosis
L Organ, B Bacci, E Koumoundouros, G Barcham, M Milne, W Kimpton, C Samuel, K Snibson |
BMC Pulmonary Medicine | 2015 |
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Amelioration of Bleomycin-induced Pulmonary Fibrosis of Rats by an Aldose Reductase Inhibitor, Epalrestat
X Li, Y Shen, Y Lu, J Yang |
The Korean Journal of Physiology & Pharmacology | 2015 |
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Reduced FoxO3a expression causes low autophagy in idiopathic pulmonary fibrosis fibroblasts on collagen matrices
J Im, P Hergert, RS Nho |
American journal of physiology. Lung cellular and molecular physiology | 2015 |
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Host Response to Biomaterials
JM Fishman, K Wiles, KJ Wood |
Host Response to Biomaterials | 2015 |
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IL-13 and TGF-β1: Core Mediators of Fibrosis
LA Borthwick, TA Wynn |
Current Pathobiology Reports | 2015 |
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Effects of jnk inhibitor on inflammation and fibrosis in the ovary tissue of a rat model of polycystic ovary syndrome
Gulay Bulut, Zehra Kurdoglu, Yeliz Bozdemir Dönmez, Mertihan Kurdoglu, Remzi Erten |
International journal of clinical and experimental pathology | 2015 |
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Studying human respiratory disease in animals - role of induced and naturally occurring models: Modelling respiratory disease in animals
K Williams, J Roman |
The Journal of Pathology | 2015 |
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Pharmacologic inhibition of lactate production prevents myofibroblast differentiation
RM Kottmann, E Trawick, JL Judge, LA Wahl, A Epa, KM Owens, TH Thatcher, RP Phipps, PJ Sime |
American journal of physiology. Lung cellular and molecular physiology | 2015 |
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The Big Book on Small Heat Shock Proteins
RM Tanguay, LE Hightower |
2015 | |
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Metformin attenuates gefitinib-induced exacerbation of pulmonary fibrosis by inhibition of TGF-β signaling pathway.
Li L, Huang W, Li K, Zhang K, Lin C, Han R, Lu C, Wang Y, Chen H, Sun F, He Y |
Oncotarget | 2015 |
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Antifibrotic Effects of Noscapine Through Activation of Prostaglandin E2 Receptors and Protein Kinase A
J Kach, N Sandbo, J La, D Denner, EB Reed, OA Akimova, S Koltsova, SN Orlov, NO Dulin |
The Journal of biological chemistry | 2014 |
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Wnt Co-receptor Lrp5 is a Driver of Idiopathic Pulmonary Fibrosis
AP Lam, JD Herazo-Maya, JA Sennello, AS Flozak, S Russell, GM Mutlu, GR Budinger, R DasGupta, J Varga, N Kaminski, CJ Gottardi |
American journal of respiratory and critical care medicine | 2014 |
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New Therapeutic Targets in Idiopathic Pulmonary Fibrosis. Aiming to Rein in Runaway Wound-Healing Responses
N Ahluwalia, BS Shea, AM Tager |
2014 | |
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Modifiers of TGF-β1 effector function as novel therapeutic targets of pulmonary fibrosis
CM Lee, JW Park, WK Cho, Y Zhou, B Han, PO Yoon, J Chae, JA Elias, CG Lee |
The Korean Journal of Internal Medicine | 2014 |
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Interleukin-1β attenuates myofibroblast formation and extracellular matrix production in dermal and lung fibroblasts exposed to transforming growth factor-β1
MM Mia, M Boersema, RA Bank |
PloS one | 2014 |
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Uncoupling between Inflammatory and Fibrotic Responses to Silica: Evidence from MyD88 Knockout Mice
SL Re, Y Yakoub, R Devosse, F Uwambayinema, I Couillin, B Ryffel, E Marbaix, D Lison, F Huaux |
PloS one | 2014 |
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Inhibition of the v 6 integrin leads to limited alteration of TGF- -induced pulmonary fibrosis
SK Madala, TR Korfhagen, S Schmidt, C Davidson, R Edukulla, M Ikegami, SM Violette, PH Weinreb, D Sheppard, WD Hardie |
American journal of physiology. Lung cellular and molecular physiology | 2014 |
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Future Directions in Idiopathic Pulmonary Fibrosis Research. An NHLBI Workshop Report
TS Blackwell, AM Tager, Z Borok, BB Moore, DA Schwartz, KJ Anstrom, Z Bar-Joseph, P Bitterman, MR Blackburn, W Bradford, KK Brown, HA Chapman, HR Collard, GP Cosgrove, R Deterding, R Doyle, KR Flaherty, CK Garcia, JS Hagood, CA Henke, E Herzog, CM Hogaboam, JC Horowitz, TE King, JE Loyd, WE Lawson, CB Marsh, PW Noble, I Noth, D Sheppard, J Olsson, LA Ortiz, TG O’Riordan, TD Oury, G Raghu, J Roman, PJ Sime, TH Sisson, D Tschumperlin, SM Violette, TE Weaver, RG Wells, ES White, N Kaminski, FJ Martinez, TA Wynn, VJ Thannickal, JP Eu |
American journal of respiratory and critical care medicine | 2014 |
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Protein Tyrosine Phosphatase α Mediates Profibrotic Signaling in Lung Fibroblasts through TGF-β Responsiveness
Y Aschner, AP Khalifah, N Briones, C Yamashita, L Dolgonos, SK Young, MN Campbell, DW Riches, EF Redente, WJ Janssen, PM Henson, J Sap, N Vacaresse, A Kapus, CA McCulloch, RL Zemans, GP Downey |
The American Journal of Pathology | 2014 |
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Epigenetics of idiopathic pulmonary fibrosis
IV Yang, DA Schwartz |
Translational Research | 2014 |
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Arsenic trioxide inhibits transforming growth factor-β1-induced fibroblast to myofibroblast differentiation in vitro and bleomycin induced lung fibrosis in vivo
F Luo, Y Zhuang, MD Sides, CG Sanchez, B Shan, ES White, JA Lasky |
Respiratory Research | 2014 |
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Early-life origins of chronic respiratory diseases: understanding and promoting healthy ageing
S Carraro, N Scheltema, L Bont, E Baraldi |
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology | 2014 |
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Intratracheal Instillation of High Dose Adenoviral Vectors Is Sufficient to Induce Lung Injury and Fibrosis in Mice
Q Zhou, T Chen, M Bozkanat, JC Ibe, JW Christman, JU Raj, G Zhou, X Su |
PloS one | 2014 |
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Matrix Metalloproteinase-9 Null Mice Are Resistant to TGF-β–Induced Anterior Subcapsular Cataract Formation
A Korol, G Pino, D Dwivedi, JV Robertson, PA Deschamps, JA West-Mays |
The American Journal of Pathology | 2014 |
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Glycosyltransferases and Glycosaminoglycans in Bleomycin and Transforming Growth Factor-β1–Induced Pulmonary Fibrosis
N Venkatesan, K Tsuchiya, M Kolb, L Farkas, M Bourhim, M Ouzzine, MS Ludwig |
American journal of respiratory cell and molecular biology | 2014 |
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Assessment of the effect of potential antifibrotic compounds on total and αVβ6 integrin-mediated TGF-β activation
J Porte, G Jenkins |
Pharmacology Research & Perspectives | 2014 |
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Emerging therapeutic interventions for idiopathic pulmonary fibrosis
S Chakraborty, P Chopra, SV Ambi, SG Dastidar, A Ray |
Expert Opinion on Investigational Drugs | 2014 |
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Heat shock proteins in fibrosis and wound healing: Good or evil?
PS Bellaye, O Burgy, S Causse, C Garrido, P Bonniaud |
Pharmacology & Therapeutics | 2014 |
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Extracellular matrix proteins: A positive feedback loop in lung fibrosis?
ME Blaauboer, FR Boeijen, CL Emson, SM Turner, B Zandieh-Doulabi, R Hanemaaijer, TH Smit, R Stoop, V Everts |
Matrix Biology | 2014 |
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Epithelial–mesenchymal transition of A549 cells is enhanced by co-cultured with THP-1 macrophages under hypoxic conditions
A Sueki, K Matsuda, C Iwashita, C Taira, N Ishimine, S Shigeto, K Kawasaki, M Sugano, H Yamamoto, T Honda |
Biochemical and Biophysical Research Communications | 2014 |
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Increased Platelet Reactivity in Idiopathic Pulmonary Fibrosis Is Mediated by a Plasma Factor
MG Crooks, A Fahim, KM Naseem, AH Morice, SP Hart, C Feghali-Bostwick |
PloS one | 2014 |
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miR-92a regulates TGF-β1-induced WISP1 expression in pulmonary fibrosis
B Berschneider, DC Ellwanger, HA Baarsma, C Thiel, C Shimbori, ES White, M Kolb, P Neth, M Königshoff |
The International Journal of Biochemistry & Cell Biology | 2014 |
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Induction of galectin-1 by TGF-β1 accelerates fibrosis through enhancing nuclear retention of Smad2
MJ Lim, J Ahn, JY Yi, MH Kim, AR Son, S Lee, DS Lim, SS Kim, MA Kang, Y Han, JY Song |
Experimental Cell Research | 2014 |
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Epithelium-dependent profibrotic milieu in the pathogenesis of idiopathic pulmonary fibrosis: current status and future directions: IPF pathogenesis
X Xu, H Dai, C Wang |
The Clinical Respiratory Journal | 2014 |
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Beyond TGFβ – Novel ways to target airway and parenchymal fibrosis
CE Boorsma, BG Dekkers, EM Dijk, K Kumawat, J Richardson, JK Burgess, AE John |
Pulmonary Pharmacology & Therapeutics | 2014 |
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Role of sirtuins in chronic obstructive pulmonary disease
P Chun |
2014 | |
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Reference Module in Biomedical Sciences
DL Sackett, RB Haynes |
2014 | |
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Uncoupling between Inflammatory and Fibrotic Responses to Silica: Evidence from MyD88 Knockout Mice
SL Re, Y Yakoub, R Devosse, F Uwambayinema, I Couillin, B Ryffel, E Marbaix, D Lison, F Huaux, TH Thatcher |
PloS one | 2014 |
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Gremlin Promotes Peritoneal Membrane Injury in an Experimental Mouse Model and Is Associated with Increased Solute Transport in Peritoneal Dialysis Patients
I Siddique, SP Curran, A Ghayur, L Liu, W Shi, CM Hoff, AS Gangji, KS Brimble, PJ Margetts |
The American Journal of Pathology | 2014 |
|
Hydroxysafflor Yellow A Attenuates Small Airway Remodeling in a Rat Model of Chronic Obstructive Pulmonary Disease
Y Wang, C Xue, F Dong, Y Peng, Y Zhang, M Jin, B Zang, L Tan |
Biological & Pharmaceutical Bulletin | 2014 |
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SFK/MEK inhibitor combination prevents metastatic outgrowth of dormant tumor cells
Lara H. El Touny, Anthony Vieira, Arnulfo Mendoza, Chand Khanna, Mark Hoenerhoff, Jeffrey E. Green |
Journal of Clinical Investigation | 2013 |
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Syndecan-2 Exerts Antifibrotic Effects by Promoting Caveolin-1-mediated Transforming Growth Factor-β Receptor I Internalization and Inhibiting Transforming Growth Factor-β1 Signaling
Y Shi, BR Gochuico, G Yu, X Tang, JC Osorio, IE Fernandez, CF Risquez, AS Patel, Y Shi, MG Wathelet, AJ Goodwin, JA Haspel, SW Ryter, EM Billings, N Kaminski, D Morse, IO Rosas |
American journal of respiratory and critical care medicine | 2013 |
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Abrogation of Eya1/Six1 disrupts the saccular phase of lung morphogenesis and causes remodeling
K Lu, R Reddy, M Berika, D Warburton, AH El-Hashash |
Developmental Biology | 2013 |
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FAK-Related Nonkinase Is a Multifunctional Negative Regulator of Pulmonary Fibrosis
Q Ding, G Cai, M Hu, Y Yang, A Zheng, Q Tang, CL Gladson, H Hayasaka, H Wu, Z You, BD Southern, LM Grove, SO Rahaman, H Fang, MA Olman |
The American Journal of Pathology | 2013 |
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Animal Models of Fibrotic Lung Disease
BB Moore, WE Lawson, TD Oury, TH Sisson, K Raghavendran, CM Hogaboam |
American journal of respiratory cell and molecular biology | 2013 |
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Potential of targeting TGF-β for organ transplant patients
M Iwashima, R Love |
Future Medicinal Chemistry | 2013 |
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Activin, neutrophils, and inflammation: just coincidence?
P Sideras, E Apostolou, A Stavropoulos, A Sountoulidis, A Gavriil, A Apostolidou, E Andreakos |
Seminars in Immunopathology | 2013 |
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The Triterpenoid CDDO-Me Inhibits Bleomycin-Induced Lung Inflammation and Fibrosis
AA Kulkarni, TH Thatcher, HM Hsiao, KC Olsen, RM Kottmann, J Morrissette, TW Wright, RP Phipps, PJ Sime |
PloS one | 2013 |
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Inhibition of HSP27 blocks fibrosis development and EMT features by promoting Snail degradation
G Wettstein, PS Bellaye, M Kolb, A Hammann, B Crestani, P Soler, J Marchal-Somme, A Hazoume, J Gauldie, A Gunther, O Micheau, M Gleave, P Camus, C Garrido, P Bonniaud |
The FASEB Journal | 2013 |
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Matrix-Producing Cells in Chronic Kidney Disease: Origin, Regulation, and Activation
R Kramann, DP DiRocco, OH Maarouf, BD Humphreys |
Current Pathobiology Reports | 2013 |
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Cytokines in chronic respiratory diseases
SP Atamas, SP Chapoval, AD Keegan |
F1000 biology reports | 2013 |
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Neonatal Hyperoxia Increases Sensitivity of Adult Mice to Bleomycin-Induced Lung Fibrosis
M Yee, BW Buczynski, BP Lawrence, MA O’Reilly |
American journal of respiratory cell and molecular biology | 2013 |
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Aortic Carboxypeptidase-like Protein (ACLP) Enhances Lung Myofibroblast Differentiation through Transforming Growth Factor Receptor-dependent and -independent Pathways
KE Tumelty, BD Smith, MA Nugent, MD Layne |
The Journal of biological chemistry | 2013 |
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Fibrosis of two: Epithelial cell-fibroblast interactions in pulmonary fibrosis
N Sakai, AM Tager |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2013 |
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Transforming growth factor-β (TGF-β) expression is increased in the subsynovial connective tissues of patients with idiopathic carpal tunnel syndrome: TGF-β EXPRESSION IN HUMAN IDIOPATHIC CTS
T Chikenji, A Gingery, C Zhao, SM Passe, Y Ozasa, D Larson, KN An, PC Amadio |
Journal of Orthopaedic Research | 2013 |
|
Rapamycin Inhibits Transforming Growth Factor β1-Induced Fibrogenesis in Primary Human Lung Fibroblasts
Y Gao, X Xu, K Ding, Y Liang, D Jiang, H Dai |
Yonsei Medical Journal | 2013 |
|
Type V Collagen Induced Tolerance Suppresses Collagen Deposition, TGF-β and Associated Transcripts in Pulmonary Fibrosis
R Vittal, EA Mickler, AJ Fisher, C Zhang, K Rothhaar, H Gu, KM Brown, A Emtiazdjoo, JM Lott, SB Frye, GN Smith, GE Sandusky, OW Cummings, DS Wilkes |
PloS one | 2013 |
|
The roles of TGFβ in the tumour microenvironment
M Pickup, S Novitskiy, HL Moses |
Nature Reviews Cancer | 2013 |
|
β-arrestins in the Immune System
Jiang D, Xie T, Liang J, Noble PW |
Progress in molecular biology and translational science | 2013 |
|
Evaluation of fibrosis in precision-cut tissue slices
IM Westra, BT Pham, GM Groothuis, P Olinga |
Xenobiotica | 2013 |
|
Lysophospholipid Receptors: Signaling and Biochemistry
CC Yun, P He |
Lysophospholipid Receptors: Signaling and Biochemistry | 2013 |
|
New agents for pleurodesis
RW Light |
Current Respiratory Care Reports | 2013 |
|
Extracellular matrix microenvironment contributes actively to pulmonary fibrosis:
C Shimbori, J Gauldie, M Kolb |
Current Opinion in Pulmonary Medicine | 2013 |
|
Dehydroepiandrosterone induces ovarian and uterine hyperfibrosis in female rats
X Zhang, C Zhang, S Shen, Y Xia, L Yi, Q Gao, Y Wang |
Human Reproduction | 2013 |
|
New treatment and markers of prognosis for idiopathic pulmonary fibrosis: lessons learned from translational research
E Baroke, J Gauldie, M Kolb |
Expert Review of Respiratory Medicine | 2013 |
|
Microvascular targets for anti-fibrotic therapeutics
KM Pu, P Sava, AL Gonzalez |
The Yale journal of biology and medicine | 2013 |
|
Hepatic fibrogenesis and transforming growth factor/Smad signaling activation in rats chronically exposed to low doses of lead: Lead-induced liver fibrogenesis
RC Aguilar, SM Honoré, SB Genta, SS Sánchez |
Journal of Applied Toxicology | 2013 |
|
Plèvre et fi brose pulmonaire
JF Bernardin, B Maitre, P Bonniaud, G Briend |
Revue des Maladies Respiratoires Actualités | 2013 |
|
Bleomycin-induced pulmonary fibrosis is attenuated by an antibody against KL-6
L Xu, D Yang, S Zhu, J Gu, F Ding, W Bian, Z Rong, C Shen |
Experimental Lung Research | 2013 |
|
The Triterpenoid CDDO-Me Inhibits Bleomycin-Induced Lung Inflammation and Fibrosis
AA Kulkarni, TH Thatcher, HM Hsiao, KC Olsen, RM Kottmann, J Morrissette, TW Wright, RP Phipps, PJ Sime, B Ryffel |
PloS one | 2013 |
|
Type V Collagen Induced Tolerance Suppresses Collagen Deposition, TGF-β and Associated Transcripts in Pulmonary Fibrosis
R Vittal, EA Mickler, AJ Fisher, C Zhang, K Rothhaar, H Gu, KM Brown, A Emtiazdjoo, JM Lott, SB Frye, GN Smith, GE Sandusky, OW Cummings, DS Wilkes, O Eickelberg |
PloS one | 2013 |
|
Autotaxin and lysophosphatidic acid signalling in lung pathophysiology
C Magkrioti |
World Journal of Respirology | 2013 |
|
Regulation of myofibroblast differentiation and bleomycin-induced pulmonary fibrosis by adrenomedullin
J Kach, N Sandbo, N Sethakorn, J Williams, EB Reed, J La, X Tian, SD Brain, K Rajendran, R Krishnan, AI Sperling, K Birukov, NO Dulin |
American journal of physiology. Lung cellular and molecular physiology | 2013 |
|
TGF-β-Smad3 signaling in emphysema and pulmonary fibrosis: an epigenetic aberration of normal development?
D Warburton, W Shi, B Xu |
American journal of physiology. Lung cellular and molecular physiology | 2013 |
|
Acellular normal and fibrotic human lung matrices as a culture system for in vitro investigation
AJ Booth, R Hadley, AM Cornett, AA Dreffs, SA Matthes, JL Tsui, K Weiss, JC Horowitz, VF Fiore, TH Barker, BB Moore, FJ Martinez, LE Niklason, ES White |
American journal of respiratory and critical care medicine | 2012 |
|
Sequential expression of IGF-IB followed by active TGF-β1 induces synergistic pulmonary fibroproliferation in vivo
G Andonegui, A Ni, C Léger, MM Kelly, JF Wong, A Jalloul, BW Winston |
American journal of physiology. Lung cellular and molecular physiology | 2012 |
|
The A2B adenosine receptor modulates pulmonary hypertension associated with interstitial lung disease
H Karmouty-Quintana, H Zhong, L Acero, T Weng, E Melicoff, JD West, A Hemnes, A Grenz, HK Eltzschig, TS Blackwell, Y Xia, RA Johnston, D Zeng, L Belardinelli, MR Blackburn |
The FASEB Journal | 2012 |
|
Mutant surfactant A2 proteins associated with familial pulmonary fibrosis and lung cancer induce TGF-β1 secretion
M Maitra, CA Cano, CK Garcia |
Proceedings of the National Academy of Sciences | 2012 |
|
Sprouty Is a Negative Regulator of Transforming Growth Factor β-Induced Epithelial-to-Mesenchymal Transition and Cataract
EH Shin, MA Basson, ML Robinson, JW McAvoy, FJ Lovicu |
Molecular Medicine | 2012 |
|
Therapeutic value of small molecule inhibitor to plasminogen activator inhibitor-1 for lung fibrosis
WT Huang, PK Vayalil, T Miyata, J Hagood, RM Liu |
American journal of respiratory cell and molecular biology | 2012 |
|
Role of the Lysophospholipid Mediators Lysophosphatidic Acid and Sphingosine 1-Phosphate in Lung Fibrosis
BS Shea, AM Tager |
Proceedings of the American Thoracic Society | 2012 |
|
Human epidermal growth factor receptor signaling in acute lung injury
JH Finigan, GP Downey, JA Kern |
American journal of respiratory cell and molecular biology | 2012 |
|
Molecular and cellular mechanisms of pulmonary fibrosis
NW Todd, IG Luzina, SP Atamas |
Fibrogenesis & Tissue Repair | 2012 |
|
Cytokine mediated tissue fibrosis
LA Borthwick, TA Wynn, AJ Fisher |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2012 |
|
Surfactant Protein-D Regulates Effector Cell Function and Fibrotic Lung Remodeling in Response to Bleomycin Injury
Y Aono, JG Ledford, S Mukherjee, H Ogawa, Y Nishioka, S Sone, MF Beers, PW Noble, JR Wright |
American journal of respiratory and critical care medicine | 2012 |
|
Rapamycin inhibits transforming growth factor β-induced peritoneal angiogenesis by blocking the secondary hypoxic response
Y Sekiguchi, J Zhang, S Patterson, L Liu, C Hamada, Y Tomino, PJ Margetts |
Journal of Cellular and Molecular Medicine | 2012 |
|
Interactions between β-catenin and transforming growth factor-β signaling pathways mediate epithelial-mesenchymal transition and are dependent on the transcriptional co-activator cAMP-response element-binding protein (CREB)-binding protein (CBP)
B Zhou, Y Liu, M Kahn, DK Ann, A Han, H Wang, C Nguyen, P Flodby, Q Zhong, MS Krishnaveni, JM Liebler, P Minoo, ED Crandall, Z Borok |
The Journal of biological chemistry | 2012 |
|
Periostin promotes fibrosis and predicts progression in patients with idiopathic pulmonary fibrosis
PK Naik, PD Bozyk, JK Bentley, AP Popova, CM Birch, CA Wilke, CD Fry, ES White, TH Sisson, N Tayob, B Carnemolla, P Orecchia, KR Flaherty, MB Hershenson, S Murray, FJ Martinez, BB Moore, |
American journal of physiology. Lung cellular and molecular physiology | 2012 |
|
Epistatic interactions between Tgfb1 and genetic loci, Tgfbm2 and Tgfbm3, determine susceptibility to an asthmatic stimulus
J Freimuth, FF Clermont, X Huang, A DeSapio, TA Tokuyasu, D Sheppard, RJ Akhurst |
Proceedings of the National Academy of Sciences | 2012 |
|
Loss of miR-29 in Myoblasts Contributes to Dystrophic Muscle Pathogenesis
L Wang, L Zhou, P Jiang, L Lu, X Chen, H Lan, DC Guttridge, H Sun, H Wang |
Molecular Therapy | 2012 |
|
Fasudil, a Rho-Kinase Inhibitor, Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice
C Jiang, H Huang, J Liu, Y Wang, Z Lu, Z Xu |
International journal of molecular sciences | 2012 |
|
Cysteine-rich protein 1 is regulated by transforming growth factor-β1 and expressed in lung fibrosis
PM Järvinen, M Myllärniemi, H Liu, HM Moore, O Leppäranta, K Salmenkivi, K Koli, L Latonen, AM Band, M Laiho |
Journal of Cellular Physiology | 2012 |
|
Pranlukast, a Cysteinyl Leukotriene Type 1 Receptor Antagonist, Attenuates the Progression but Not the Onset of Silica-Induced Pulmonary Fibrosis in Mice
C Shimbori, N Shiota, H Okunishi |
International Archives of Allergy and Immunology | 2012 |
|
Sequential Analysis of Myofibroblast Differentiation and Transforming Growth Factor-β1/Smad Pathway Activation in Murine Pulmonary Fibrosis
J Usuki, K Matsuda, A Azuma, S Kudoh, A Gemma |
Journal of Nippon Medical School | 2012 |
|
Regulation of TGF-β storage and activation in the human idiopathic pulmonary fibrosis lung
O Leppäranta, C Sens, K Salmenkivi, VL Kinnula, J Keski-Oja, M Myllärniemi, K Koli |
Cell & Tissue Research | 2012 |
|
A cytokine axis regulates elastin formation and degradation
EP Sproul, WS Argraves |
Matrix Biology | 2012 |
|
Homeodomain-interacting protein kinase2 in human idiopathic pulmonary fibrosis
A Ricci, E Cherubini, A Ulivieri, L Lavra, S Sciacchitano, D Scozzi, R Mancini, G Ciliberto, A Bartolazzi, P Bruno, P Graziano, S Mariotta |
Journal of Cellular Physiology | 2012 |
|
Osteoarthritis-related fibrosis is associated with both elevated pyridinoline cross-link formation and lysyl hydroxylase 2b expression
DF Remst, EN Davidson, EL Vitters, AB Blom, R Stoop, JM Snabel, RA Bank, WB Berg, PM der Kraan |
Osteoarthritis and Cartilage | 2012 |
|
Targeting Focal Adhesion Kinase in Fibrotic Diseases
D Lagares, M Kapoor |
BioDrugs | 2012 |
|
Organ fibrosis inhibited by blocking transforming growth factor-β signaling via peroxisome proliferator-activated receptor γ agonists
YL Deng, XZ Xiong, NS Cheng |
Hepatobiliary & Pancreatic Diseases International | 2012 |
|
Lactic Acid Is Elevated in Idiopathic Pulmonary Fibrosis and Induces Myofibroblast Differentiation via pH-Dependent Activation of Transforming Growth Factor-β
RM Kottmann, AA Kulkarni, KA Smolnycki, E Lyda, T Dahanayake, R Salibi, S Honnons, C Jones, NG Isern, JZ Hu, SD Nathan, G Grant, RP Phipps, PJ Sime |
American journal of respiratory and critical care medicine | 2012 |
|
Developmental responses to lung injury: repair or fibrosis
D Warburton |
Fibrogenesis & Tissue Repair | 2012 |
|
TGFβ1 Controls PPARγ Expression, Transcriptional Potential, and Activity, in Part, through Smad3 Signaling in Murine Lung Fibroblasts
A Ramirez, EN Ballard, J Roman |
PPAR Research | 2012 |
|
Developmental nicotine exposure results in programming of alveolar simplification and interstitial pulmonary fibrosis in adult male rats
C Dasgupta, DL Xiao, Z Xu, S Yang, L Zhang |
Reproductive toxicology (Elmsford, N.Y.) | 2012 |
|
Transforming growth factor β suppresses glutamate-cysteine ligase gene expression and induces oxidative stress in a lung fibrosis model
RM Liu, PK Vayalil, C Ballinger, DA Dickinson, WT Huang, S Wang, TJ Kavanagh, QL Matthews, EM Postlethwait |
Free radical biology & medicine | 2012 |
|
Mechanical Aspects of Lung Fibrosis: A Spotlight on the Myofibroblast
B Hinz |
Proceedings of the American Thoracic Society | 2012 |
|
TGF-β Activation and Lung Fibrosis
AL Tatler, G Jenkins |
Proceedings of the American Thoracic Society | 2012 |
|
Losartan Enhances the Success of Myoblast Transplantation
R Fakhfakh, Y Lamarre, D Skuk, JP Tremblay |
Cell Transplantation | 2012 |
|
Periostin promotes fibrosis and predicts progression in patients with idiopathic pulmonary fibrosis
PK Naik, PD Bozyk, JK Bentley, AP Popova, CM Birch, CA Wilke, CD Fry, ES White, TH Sisson, N Tayob, B Carnemolla, P Orecchia, KR Flaherty, MB Hershenson, S Murray, FJ Martinez, BB Moore |
American journal of physiology. Lung cellular and molecular physiology | 2012 |
|
Myostatin-null mice exhibit delayed skin wound healing through the blockade of transforming growth factor-β signaling by decorin
C Zhang, CK Tan, C McFarlane, M Sharma, NS Tan, R Kambadur |
American journal of physiology. Cell physiology | 2012 |
|
Allele-specific transactivation of matrix metalloproteinase 7 by FOXA2 and correlation with plasma levels in idiopathic pulmonary fibrosis
TJ Richards, C Park, Y Chen, KF Gibson, YP Di, A Pardo, SC Watkins, AM Choi, M Selman, J Pilewski, N Kaminski, Y Zhang |
American journal of physiology. Lung cellular and molecular physiology | 2012 |
|
Adenovirus-mediated gene transfer of TGF-β1 to the renal glomeruli leads to proteinuria
A Ghayur, L Liu, M Kolb, A Chawla, S Lambe, A Kapoor, PJ Margetts |
The American Journal of Pathology | 2011 |
|
Matrix Metalloproteinase 3 Is a Mediator of Pulmonary Fibrosis
CM Yamashita, L Dolgonos, RL Zemans, SK Young, J Robertson, N Briones, T Suzuki, MN Campbell, J Gauldie, DC Radisky, DW Riches, G Yu, N Kaminski, CA McCulloch, GP Downey |
The American Journal of Pathology | 2011 |
|
Regulation of Transforming Growth Factor-β1–driven Lung Fibrosis by Galectin-3
AC Mackinnon, MA Gibbons, SL Farnworth, H Leffler, UJ Nilsson, T Delaine, AJ Simpson, SJ Forbes, N Hirani, J Gauldie, T Sethi |
American journal of respiratory and critical care medicine | 2011 |
|
Severe lung fibrosis requires an invasive fibroblast phenotype regulated by hyaluronan and CD44
Y Li, D Jiang, J Liang, EB Meltzer, A Gray, R Miura, L Wogensen, Y Yamaguchi, PW Noble |
Journal of Experimental Medicine | 2011 |
|
Lung-Targeted Overexpression of the NF-κB Member RelB Inhibits Cigarette Smoke–Induced Inflammation
DH McMillan, CJ Baglole, TH Thatcher, S Maggirwar, PJ Sime, RP Phipps |
The American Journal of Pathology | 2011 |
|
Increased transforming growth factor beta 1 expression mediates ozone-induced airway fibrosis in mice
A Katre, C Ballinger, H Akhter, M Fanucchi, DK Kim, E Postlethwait, RM Liu |
Inhalation Toxicology | 2011 |
|
Boswellic acids extract attenuates pulmonary fibrosis induced by bleomycin and oxidative stress from gamma irradiation in rats
EN Ali, SZ Mansour |
Chinese medicine | 2011 |
|
Cross talk among TGF-β signaling pathways, integrins, and the extracellular matrix
JS Munger, D Sheppard |
Cold Spring Harbor perspectives in biology | 2011 |
|
Vimentin is sufficient and required for wound repair and remodeling in alveolar epithelial cells
MR Rogel, PN Soni, JR Troken, A Sitikov, HE Trejo, KM Ridge |
The FASEB Journal | 2011 |
|
PROGRESS TOWARD IMPROVING ANIMAL MODELS FOR IPF
AL Degryse, WE Lawson |
The American Journal of the Medical Sciences | 2011 |
|
Regulation and function of miRNA-21 in health and disease
R Kumarswamy, I Volkmann, T Thum |
RNA biology | 2011 |
|
TGF-β signaling in fibrosis
A Biernacka, M Dobaczewski, NG Frangogiannis |
Growth Factors | 2011 |
|
Novel therapeutic approaches for pulmonary fibrosis
A Datta, CJ Scotton, RC Chambers |
British Journal of Pharmacology | 2011 |
|
New Insights into the Pathogenesis and Treatment of IPF: An Update
Q Ding, T Luckhardt, L Hecker, Y Zhou, G Liu, VB Antony, J deAndrade, VJ Thannickal |
Drugs | 2011 |
|
Transglutaminase 2 and Its Role in Pulmonary Fibrosis
KC Olsen, RE Sapinoro, RM Kottmann, AA Kulkarni, SE Iismaa, GV Johnson, TH Thatcher, RP Phipps, PJ Sime |
American journal of respiratory and critical care medicine | 2011 |
|
Potential Role of the Inflammasome-Derived Inflammatory Cytokines in Pulmonary Fibrosis
R Biswas, M Bunderson-Schelvan, A Holian |
Pulmonary Medicine | 2011 |
|
Alveolar Epithelial Cells Undergo Epithelial-to-Mesenchymal Transition in Response to Endoplasmic Reticulum Stress*
H Tanjore, DS Cheng, AL Degryse, DF Zoz, R Abdolrasulnia, WE Lawson, TS Blackwell |
The Journal of biological chemistry | 2011 |
|
TGFβ signaling in lung epithelium regulates bleomycin-induced alveolar injury and fibroblast recruitment
AL Degryse, H Tanjore, XC Xu, VV Polosukhin, BR Jones, CS Boomershine, C Ortiz, TP Sherrill, FB McMahon, LA Gleaves, TS Blackwell, WE Lawson |
AJP Lung Cellular and Molecular Physiology | 2011 |
|
Inflammation and Allergy Drug Design
K Arima, YJ Liu |
Inflammation and Allergy Drug Design | 2011 |
|
Lack of Association Between the TGF-β1 Gene and Development of COPD in Asians: A Case–Control Study and Meta-analysis
Y Gong, L Fan, H Wan, Y Shi, G Shi, Y Feng, J Liu, L Ni, C Pan, R Zhang |
Lung | 2011 |
|
Mitigation of radiation-induced lung injury by genistein and EUK-207
J Mahmood, S Jelveh, V Calveley, A Zaidi, SR Doctrow, RP Hill |
International Journal of Radiation Biology | 2011 |
|
Inhibitory Effect of Safflor Yellow on Pulmonary Fibrosis
L Wang, M Jin, BX Zang, Y Wu |
Biological & Pharmaceutical Bulletin | 2011 |
|
An investigator-driven study of everolimus in surgical lung biopsy confirmed idiopathic pulmonary fibrosis
MA Malouf, P Hopkins, G Snell, AR Glanville |
Respirology | 2011 |
|
Matrix metalloprotease-9 induces transforming growth factor-β1 production in airway epithelium via activation of epidermal growth factor receptors
DW Perng, KT Chang, KC Su, YC Wu, CS Chen, WH Hsu, CM Tsai, YC Lee |
Life Sciences | 2011 |
|
Post-transcriptional up-regulation of miR-21 by type I collagen
C Li, HT Nguyen, Y Zhuang, Y Lin, EK Flemington, W Guo, J Guenther, ME Burow, GF Morris, D Sullivan, B Shan |
Molecular Carcinogenesis | 2011 |
|
Quantitative Measurement of Bleomycin-induced Lung Fibrosis in Rabbits Using Sequential in vivo Regional Analysis and High-Resolution Computed Tomography:
Y Nagatani, N Nitta, H Otani, K Mukaisho, A Sonoda, A Nitta-Seko, M Takahashi, K Murata |
Academic Radiology | 2011 |
|
Oxidative stress contributes to the induction and persistence of TGF-β1 induced pulmonary fibrosis
Y Cui, J Robertson, S Maharaj, L Waldhauser, J Niu, J Wang, L Farkas, M Kolb, J Gauldie |
The International Journal of Biochemistry & Cell Biology | 2011 |
|
Blockade of the Wnt/β-Catenin Pathway Attenuates Bleomycin-Induced Pulmonary Fibrosis
TH Kim, SH Kim, JY Seo, H Chung, HJ Kwak, SK Lee, HJ Yoon, DH Shin, SS Park, JW Sohn |
The Tohoku Journal of Experimental Medicine | 2011 |
|
Effects of montelukast, a cysteinyl-leukotriene type 1 receptor antagonist, on the pathogenesis of bleomycin-induced pulmonary fibrosis in mice
C Shimbori, N Shiota, H Okunishi |
European Journal of Pharmacology | 2011 |
|
Electrophilic PPARγ ligands inhibit corneal fibroblast to myofibroblast differentiation in vitro: A potentially novel therapy for corneal scarring
AE Kuriyan, GM Lehmann, AA Kulkarni, CF Woeller, SE Feldon, HB Hindman, P Sime, KR Huxlin, RP Phipps |
Experimental Eye Research | 2011 |
|
mSmile is Necessary for Bronchial Smooth Muscle and Alveolar Myofibroblast Development
EJ Yun, TH Vu |
The Anatomical Record Advances in Integrative Anatomy and Evolutionary Biology | 2011 |
|
CD4+CD25+Foxp3+ regulatory T cells suppress cardiac fibrosis in the hypertensive heart :
P Kanellakis, TN Dinh, A Agrotis, A Bobik |
Journal of Hypertension | 2011 |
|
Ocular Fibroblast Diversity: Implications for Inflammation and Ocular Wound Healing
X Xi, DH McMillan, GM Lehmann, PJ Sime, RT Libby, KR Huxlin, SE Feldon, RP Phipps |
Investigative ophthalmology & visual science | 2011 |
|
LIM-domain proteins in transforming growth factor β-induced epithelial-to-mesenchymal transition and myofibroblast differentiation
PM Järvinen, M Laiho |
Cellular Signalling | 2011 |
|
Idiopathic Pulmonary Fibrosis: Pathobiology of Novel Approaches to Treatment
TM Maher |
Clinics in Chest Medicine | 2011 |
|
Oxidative Stress and Disease: The Silent Link
H Yao, I Rahman |
Oxidative Stress and Disease: The Silent Link | 2011 |
|
Pulmonary Hypertension and Idiopathic Pulmonary Fibrosis: A Tale of Angiogenesis, Apoptosis, and Growth Factors
L Farkas, J Gauldie, NF Voelkel, M Kolb |
American journal of respiratory cell and molecular biology | 2011 |
|
Actin cytoskeleton in myofibroblast differentiation: ultrastructure defining form and driving function
N Sandbo, N Dulin |
Translational research : the journal of laboratory and clinical medicine | 2011 |
|
Let It Be: microRNAs Impact Interstitial Lung Disease
WE Lawson, TS Blackwell, J Gauldie |
American journal of respiratory and critical care medicine | 2011 |
|
Role of growth factors in acute lung injury induced by paraquat in a rat model
X Jian, M Li, Y Zhang, Y Ruan, G Guo, H Sui, Y Zhang |
Human & Experimental Toxicology | 2011 |
|
Alveolar Epithelial Cells Undergo Epithelial-to-Mesenchymal Transition in Response to Endoplasmic Reticulum Stress
H Tanjore, DS Cheng, AL Degryse, DF Zoz, R Abdolrasulnia, WE Lawson, TS Blackwell |
The Journal of biological chemistry | 2011 |
|
Hypoxia-inducible factor-1α mediates TGF-β-induced PAI-1 production in alveolar macrophages in pulmonary fibrosis
M Ueno, T Maeno, M Nomura, K Aoyagi-Ikeda, H Matsui, K Hara, T Tanaka, T Iso, T Suga, M Kurabayashi |
American journal of physiology. Lung cellular and molecular physiology | 2011 |
|
TGFβ signaling in lung epithelium regulates bleomycin-induced alveolar injury and fibroblast recruitment
AL Degryse, H Tanjore, XC Xu, VV Polosukhin, BR Jones, CS Boomershine, C Ortiz, TP Sherrill, FB McMahon, LA Gleaves, TS Blackwell, WE Lawson |
American journal of physiology. Lung cellular and molecular physiology | 2011 |
|
Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-β-induced senescence of human bronchial epithelial cells
S Minagawa, J Araya, T Numata, S Nojiri, H Hara, Y Yumino, M Kawaishi, M Odaka, T Morikawa, SL Nishimura, K Nakayama, K Kuwano |
American journal of physiology. Lung cellular and molecular physiology | 2011 |
|
Chronic intermittent hypoxia induces lung growth in adult mice
C Reinke, S Bevans-Fonti, DN Grigoryev, LF Drager, AC Myers, RA Wise, AR Schwartz, W Mitzner, VY Polotsky |
American journal of physiology. Lung cellular and molecular physiology | 2011 |
|
TRIP-1 regulates TGF-β1-induced epithelial-mesenchymal transition of human lung epithelial cell line A549
RE Perez, A Navarro, MH Rezaiekhaligh, SM Mabry, II Ekekezie |
American journal of physiology. Lung cellular and molecular physiology | 2011 |
|
PPAR-γ Ligands Repress TGFβ-Induced Myofibroblast Differentiation by Targeting the PI3K/Akt Pathway: Implications for Therapy of Fibrosis
AA Kulkarni, TH Thatcher, KC Olsen, SB Maggirwar, RP Phipps, PJ Sime, RK Aziz |
PloS one | 2011 |
|
Intratracheal Transplantation of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Dose-Dependently Attenuates Hyperoxia-Induced Lung Injury in Neonatal Rats
YS Chang, SJ Choi, DK Sung, SY Kim, W Oh, YS Yang, WS Park |
Cell Transplantation | 2011 |
|
Epithelial-Specific Deletion of Transforming Growth Factor-beta Receptor Type II Protects against Bleomycin-induced Pulmonary Fibrosis
Min Li, Manda Sai Krishnaveni, Changgong Li, Beiyun Zhou, Yiming Xing, Agnes Banfalvi, Aimin Li, Vincent Lombardi, Omid Akbari, Zea Borok, Parvis Minoo |
Journal of Clinical Investigation | 2010 |
|
Yin Yang 1 Is a Novel Regulator of Pulmonary Fibrosis
X Lin, PJ Sime, H Xu, MA Williams, L LaRussa, SN Georas, J Guo |
American journal of respiratory and critical care medicine | 2010 |
|
Comprehensive Physiology
R Terjung |
Comprehensive Physiology | 2010 |
|
Comprehensive Physiology
R Terjung |
Comprehensive Physiology | 2010 |
|
Comprehensive Physiology
R Terjung |
Comprehensive Physiology | 2010 |
|
Comprehensive Physiology
R Terjung |
Comprehensive Physiology | 2010 |
|
Notch signaling in the vasculature
T Gridley |
Current topics in developmental biology | 2010 |
|
Distinct Roles for the A 2B Adenosine Receptor in Acute and Chronic Stages of Bleomycin-Induced Lung Injury
Y Zhou, DJ Schneider, E Morschl, L Song, M Pedroza, H Karmouty-Quintana, T Le, CX Sun, MR Blackburn |
Journal of immunology (Baltimore, Md. : 1950) | 2010 |
|
Oxidative stress and glutathione in TGF-β-mediated fibrogenesis
RM Liu, KA Pravia |
Free radical biology & medicine | 2010 |
|
A prostacyclin analogue, iloprost, protects from bleomycin-induced pulmonary fibrosis in mice
Y Zhu, Y Liu, W Zhou, R Xiang, L Jiang, K Huang, Y Xiao, Z Guo, J Gao |
Respiratory Research | 2010 |
|
Genome-Wide Transcriptional Response During the Development of Bleomycin-Induced Pulmonary Fibrosis in Sprague-Dawley Rats
HJ Park, MJ Yang, JH Oh, YS Yang, MS Kwon, CW Song, SJ Yoon |
Toxicological Research | 2010 |
|
Overexpression of Smad2 drives house dust mite-mediated airway remodeling and airway hyperresponsiveness via activin and IL-25
LG Gregory, SA Mathie, SA Walker, S Pegorier, CP Jones, CM Lloyd |
American journal of respiratory and critical care medicine | 2010 |
|
Transient Overexpression of Gremlin Results in Epithelial Activation and Reversible Fibrosis in Rat Lungs
L Farkas, D Farkas, J Gauldie, D Warburton, W Shi, M Kolb |
American journal of respiratory cell and molecular biology | 2010 |
|
The calpain inhibitor calpeptin prevents bleomycin-induced pulmonary fibrosis in mice
C Tabata, R Tabata, T Nakano |
Clinical & Experimental Immunology | 2010 |
|
Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-β-induced senescence of human bronchial epithelial cells
S Minagawa, J Araya, T Numata, S Nojiri, H Hara, Y Yumino, M Kawaishi, M Odaka, T Morikawa, SL Nishimura, K Nakayama, K Kuwano |
AJP Lung Cellular and Molecular Physiology | 2010 |
|
Chronic intermittent hypoxia induces lung growth in adult mice
C Reinke, S Bevans-Fonti, DN Grigoryev, LF Drager, AC Myers, RA Wise, AR Schwartz, W Mitzner, VY Polotsky |
AJP Lung Cellular and Molecular Physiology | 2010 |
|
Chronic inflammation and asthma
JR Murdoch, CM Lloyd |
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis | 2010 |
|
Eosinophils in innate immunity: an evolving story
R Shamri, JJ Xenakis, LA Spencer |
Cell & Tissue Research | 2010 |
|
Targeting Fibrosis in Duchenne Muscular Dystrophy
L Zhou, H Lu |
Journal of Neuropathology and Experimental Neurology | 2010 |
|
TGF-β: Titan of Lung Fibrogenesis
X Yue, B Shan, JA Lasky |
Current Enzyme Inhibition | 2010 |
|
miR-29 Is a Major Regulator of Genes Associated with Pulmonary Fibrosis
L Cushing, PP Kuang, J Qian, F Shao, J Wu, F Little, VJ Thannickal, WV Cardoso, J Lü |
American journal of respiratory cell and molecular biology | 2010 |
|
Fibrogenesis
Munger JS, Rom WN |
2010 | |
|
Fibrogenic Reactions in Lung Disease
J Araya, SL Nishimura |
Annual Review of Pathology: Mechanisms of Disease | 2010 |
|
Lung epithelial wound healing in health and disease
A Gardner, LA Borthwick, AJ Fisher |
Expert Review of Respiratory Medicine | 2010 |
|
Tumor necrosis factor-αα enhances both epithelial-mesenchymal transition and cell contraction induced in A549 human alveolar epithelial cells by transforming growth factor-ββ1
Y Yamauchi, T Kohyama, H Takizawa, S Kamitani, M Desaki, K Takami, S Kawasaki, J Kato, T Nagase |
Experimental Lung Research | 2010 |
|
LSKL, a peptide antagonist of thrombospondin-1, attenuates renal interstitial fibrosis in rats with unilateral ureteral obstruction
X Xie, F Li, H Liu, Y Deng, Z Li, J Fan |
Archives of Pharmacal Research | 2010 |
|
Protective Effect of Urinary Trypsin Inhibitor on the Development of Radiation-Induced Lung Fibrosis in Mice
H KATOH, H ISHIKAWA, M HASEGAWA, Y YOSHIDA, Y SUZUKI, T OHNO, T TAKAHASHI, T NAKANO |
Journal of Radiation Research | 2010 |
|
Have advanced research technologies made real impact on respiratory medicine?
K ASK, O EICKELBERG, J GAULDIE, N KAMINSKI, M KOLB |
Respirology | 2010 |
|
Prolidase-dependent regulation of TGF c and TGF β receptor expressions in human skin fibroblasts
A Surazynski, W Miltyk, I Prokop, J Palka |
European Journal of Pharmacology | 2010 |
|
Overexpression of transforming growth factor-β1 in fetal monkey lung results in prenatal pulmonary fibrosis
AF Tarantal, H Chen, TT Shi, CH Lu, AB Fang, S Buckley, M Kolb, J Gauldie, D Warburton, W Shi |
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology | 2010 |
|
Murray and Nadel's Textbook of Respiratory Medicine
MA Matthay, TR Martin |
Murray and Nadel's Textbook of Respiratory Medicine | 2010 |
|
IN-1233, an ALK-5 Inhibitor: Prevention of Granulation Tissue Formation after Bare Metallic Stent Placement in a Rat Urethral Model 1
JH Kim, HY Song, JH Park, HJ Yoon, HG Park, DK Kim |
Radiology | 2010 |
|
Micro-computed tomography of pulmonary fibrosis in mice induced by adenoviral gene transfer of biologically active transforming growth factor-β1
T Rodt, C Falck, S Dettmer, R Halter, R Maus, K Ask, M Kolb, J Gauldie, F Länger, L Hoy, T Welte, M Galanski, UA Maus, J Borlak |
Respiratory Research | 2010 |
|
The pathogenesis of idiopathic pulmonary fibrosis
WR Coward, G Saini, G Jenkins |
Therapeutic advances in respiratory disease | 2010 |
|
Adenovirus-mediated gene transfer of hIGF-IB in mouse lungs induced prolonged inflammation but no fibroproliferation
C Léger, A Ni, G Andonegui, J Wong, C Mowat, BW Winston |
American journal of physiology. Lung cellular and molecular physiology | 2010 |
|
Spaceflight modulates expression of extracellular matrix, adhesion, and profibrotic molecules in mouse lung
J Tian, MJ Pecaut, JM Slater, DS Gridley |
Journal of applied physiology | 2010 |
|
Molecular Basis of Pulmonary Disease
FX McCormack, RJ Panos, BC Trapnell |
2010 | |
|
Hydrogen sulfide attenuates epithelial–mesenchymal transition of human alveolar epithelial cells
LP Fang, Q Lin, CS Tang, XM Liu |
Pharmacological research : the official journal of the Italian Pharmacological Society | 2010 |
|
Metastatic Growth from Dormant Cells Induced by a Col-I–Enriched Fibrotic Environment
D Barkan, LH Touny, AM Michalowski, JA Smith, I Chu, AS Davis, JD Webster, S Hoover, RM Simpson, J Gauldie, JE Green |
Cancer research | 2010 |
|
VEGF ameliorates pulmonary hypertension through inhibition of endothelial apoptosis in experimental lung fibrosis
Laszlo Farkas, Kjetil Ask, Daniela Farkas, Antje Moeller, Jack Gauldie, Peter J. Margetts, Mark D. Inman, Martin R.J. Kolb |
Journal of Clinical Investigation | 2009 |
|
Emerging Concepts in the Pathogenesis of Lung Fibrosis
WD Hardie, SW Glasser, JS Hagood |
The American Journal of Pathology | 2009 |
|
Integrin-mediated transforming growth factor-beta activation, a potential therapeutic target in fibrogenic disorders
SL Nishimura |
The American Journal of Pathology | 2009 |
|
The pericyte: cellular regulator of microvascular blood flow
ME Kutcher, IM Herman |
Microvascular Research | 2009 |
|
Determinants of initiation and progression of idiopathic pulmonary fibrosis
RM KOTTMANN, CM HOGAN, RP PHIPPS, PJ SIME |
Respirology | 2009 |
|
New mechanisms of pulmonary fibrosis
RM Strieter, B Mehrad |
Chest | 2009 |
|
Update on models of pulmonary fibrosis therapy for preclinical drug research
SA Antoniu, MR Kolb |
Expert Opinion on Drug Discovery | 2009 |
|
Pulmonary fibrosis: pathogenesis, etiology and regulation
MS Wilson, TA Wynn |
Mucosal Immunology | 2009 |
|
Contribution of epithelial-derived fibroblasts to bleomycin-induced lung fibrosis
H Tanjore, XC Xu, VV Polosukhin, AL Degryse, B Li, W Han, TP Sherrill, D Plieth, EG Neilson, TS Blackwell, WE Lawson |
American journal of respiratory and critical care medicine | 2009 |
|
Pleural mesothelial cell transformation into myofibroblasts and haptotactic migration in response to TGF-beta1 in vitro
N Nasreen, KA Mohammed, KK Mubarak, MA Baz, OA Akindipe, S Fernandez-Bussy, VB Antony |
American journal of physiology. Lung cellular and molecular physiology | 2009 |
|
Androgen deprivation modulates the inflammatory response induced by irradiation
CT Wu, WC Chen, PY Lin, SK Liao, MF Chen |
BMC Cancer | 2009 |
|
Abrogation of TGF-beta1-induced fibroblast-myofibroblast differentiation by histone deacetylase inhibition
W Guo, B Shan, RC Klingsberg, X Qin, JA Lasky |
American journal of physiology. Lung cellular and molecular physiology | 2009 |
|
Intestinal fibrosis in IBD—a dynamic, multifactorial process
F Rieder, C Fiocchi |
Nature Reviews Gastroenterology & Hepatology | 2009 |
|
Development, repair and fibrosis: What is common and why it matters
W Shi, J Xu, D Warburton |
Respirology | 2009 |
|
Endothelin-1 and transforming growth factor-beta1 independently induce fibroblast resistance to apoptosis via AKT activation
P Kulasekaran, CA Scavone, DS Rogers, DA Arenberg, VJ Thannickal, JC Horowitz |
American journal of respiratory cell and molecular biology | 2009 |
|
Altered production of extra-cellular matrix components by muscle-derived Duchenne muscular dystrophy fibroblasts before and after TGF-β1 treatment
S Zanotti, S Gibertini, M Mora |
Cell and Tissue Research | 2009 |
|
IL-4 increases CD21-dependent infection of pulmonary alveolar epithelial type II cells by EBV
AP Malizia, JJ Egan, PP Doran |
Molecular Immunology | 2009 |
|
Treatment of idiopathic interstitial pneumonias
TJ Corte, AU Wells |
Expert Review of Respiratory Medicine | 2009 |
|
Smad3-dependent and -independent pathways are involved in peritoneal membrane injury
P Patel, Y Sekiguchi, KH Oh, SE Patterson, MR Kolb, PJ Margetts |
Kidney International | 2009 |
|
Idiopathic Pulmonary Fibrosis: New Concept of Pathogenesis and Treatment
ST Uh |
Journal of the Korean Medical Association | 2009 |
|
Epithelial-mesenchymal transition induced by transforming growth factor-β1 in mouse tracheal epithelial cells
S KUROISHI, T SUDA, T FUJISAWA, K IDE, N INUI, Y NAKAMURA, H NAKAMURA, K CHIDA |
Respirology | 2009 |
|
Electrophilic peroxisome proliferator-activated receptor-gamma ligands have potent antifibrotic effects in human lung fibroblasts
HE Ferguson, A Kulkarni, GM Lehmann, TM Garcia-Bates, TH Thatcher, KR Huxlin, RP Phipps, PJ Sime |
American journal of respiratory cell and molecular biology | 2009 |
|
Latent transforming growth factor-beta-binding protein-4 regulates transforming growth factor-beta1 bioavailability for activation by fibrogenic lung fibroblasts in response to bleomycin
Y Zhou, K Koli, JS Hagood, M Miao, M Mavalli, DB Rifkin, JE Murphy-Ullrich |
The American Journal of Pathology | 2009 |
|
Idiopathic pulmonary fibrosis: Now less idiopathic?
RM Bois |
Respiratory Medicine | 2009 |
|
Elevated plasma TGF-β1 levels in patients with chronic obstructive pulmonary disease
JC Mak, MM Chan-Yeung, SP Ho, KS Chan, K Choo, KS Yee, CH Chau, AH Cheung, MS Ip |
Respiratory Medicine | 2009 |
|
Asthma and COPD
SA Shore, SD Shapiro |
Asthma and COPD | 2009 |
|
Fibroblasts
LA Murray, DA Knight, GJ Laurent |
Asthma and COPD | 2009 |
|
Airway Remodeling
ST Holgate |
Asthma and COPD | 2009 |
|
Growth Factors
M Kolb, Z Xing, K Ask, J Gauldie |
Asthma and COPD | 2009 |
|
Ultrastructural Features of Lung Fibroblast Differentiation into Myofibroblasts
R Kaarteenaho-Wiik, P Pääkkö, R Sormunen |
Ultrastructural Pathology | 2009 |
|
PDGF-Rα gene expression predicts proliferation, but PDGF-A suppresses transdifferentiation of neonatal mouse lung myofibroblasts
PW Kimani, AJ Holmes, RE Grossmann, SE McGowan |
Respiratory Research | 2009 |
|
PDE4 inhibitors roflumilast and rolipram augment PGE 2 inhibition of TGF-β1-stimulated fibroblasts
S Togo, X Liu, X Wang, H Sugiura, K Kamio, S Kawasaki, T Kobayashi, RF Ertl, Y Ahn, O Holz, H Magnussen, K Fredriksson, CM Skold, SI Rennard |
American journal of physiology. Lung cellular and molecular physiology | 2009 |
|
Abrogation of TGF-β1-induced fibroblast-myofibroblast differentiation by histone deacetylase inhibition
W Guo, B Shan, RC Klingsberg, X Qin, JA Lasky |
American journal of physiology. Lung cellular and molecular physiology | 2009 |
|
Pleural mesothelial cell transformation into myofibroblasts and haptotactic migration in response to TGF-β1 in vitro
N Nasreen, KA Mohammed, KK Mubarak, MA Baz, OA Akindipe, S Fernandez-Bussy, VB Antony |
American journal of physiology. Lung cellular and molecular physiology | 2009 |
|
Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Attenuate Hyperoxia-Induced Lung Injury in Neonatal Rats
YS Chang, W Oh, SJ Choi, DK Sung, SY Kim, EY Choi, S Kang, HJ Jin, YS Yang, WS Park |
Cell Transplantation | 2009 |
|
Pulmonary Arterial Hypertension and Interstitial Lung Diseases
RP Baughman, RG Carbone, G Bottino |
2009 | |
|
Molecular Biology of the SARS-Coronavirus
SK Lal |
2009 | |
|
Prolonged Peritoneal Gene Expression Using a Helper-Dependent Adenovirus
L Liu, CX Shi, A Ghayur, C Zhang, JY Su, CM Hoff, PJ Margetts |
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis | 2009 |
|
SARS Coronavirus and Lung Fibrosis
Zuo W, Zhao X, Chen YG |
2009 | |
|
Pin1 regulates eosinophil TGF-beta1 production and allergic lung fibrosis
Zhong-Jian Shen, Stephane Esnault, Louis A. Rosenthal, Renee J. Szakaly, Ronald L. Sorkness, , Pamela R. Westmark, Matyas Sandor and James S. Malter |
Journal of Clinical Investigation | 2008 |
|
Bile acids induce CCN2 production through p38 MAP kinase activation in human bronchial epithelial cells: a factor contributing to airway fibrosis
DW PERNG, YC WU, CC TSAI, KC SU, LY LIU, WH HSU, YC LEE |
Respirology | 2008 |
|
Regulation of alveologenesis clinical implications of impaired growth
C Galambos, DE DeMello |
Pathology | 2008 |
|
Procoagulant signalling mechanisms in lung inflammation and fibrosis: novel opportunities for pharmacological intervention?
RC Chambers |
British Journal of Pharmacology | 2008 |
|
Protein kinase B/Akt activity is involved in renal TGF-beta1-driven epithelial-mesenchymal transition in vitro and in vivo
JJ Kattla, RM Carew, M Heljic, C Godson, DP Brazil |
American journal of physiology. Renal physiology | 2008 |
|
Cellular and molecular mechanisms of fibrosis
TA Wynn |
The Journal of Pathology | 2008 |
|
What differentiates normal lung repair and fibrosis? Inflammation, resolution of repair, and fibrosis
RM Strieter |
Proceedings of the American Thoracic Society | 2008 |
|
Relevance of granulocyte apoptosis to resolution of inflammation at the respiratory mucosa
AE Leitch, R Duffin, C Haslett, AG Rossi |
Mucosal Immunology | 2008 |
|
Transforming growth factor-beta1 induces heparan sulfate 6-O-endosulfatase 1 expression in vitro and in vivo
X Yue, X Li, HT Nguyen, DR Chin, DE Sullivan, JA Lasky |
The Journal of biological chemistry | 2008 |
|
Dual-immunohistochemistry provides little evidence for epithelial–mesenchymal transition in pulmonary fibrosis
M Yamada, K Kuwano, T Maeyama, N Hamada, M Yoshimi, Y Nakanishi, M Kasper |
Histochemistry and Cell Biology | 2008 |
|
Tissue transglutaminase contributes to interstitial renal fibrosis by favoring accumulation of fibrillar collagen through TGF-beta activation and cell infiltration
N Shweke, N Boulos, C Jouanneau, S Vandermeersch, G Melino, JC Dussaule, C Chatziantoniou, P Ronco, JJ Boffa |
The American Journal of Pathology | 2008 |
|
Attenuation of obliterative bronchiolitis by a CXCR4 antagonist in the murine heterotopic tracheal transplant model
J Xu, E Torres, AL Mora, H Shim, A Ramirez, D Neujahr, KL Brigham, M Rojas |
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation | 2008 |
|
Targeting tissue angiotensin-converting enzyme for imaging cardiopulmonary fibrosis
O Aras, V Dilsizian |
Current Cardiology Reports | 2008 |
|
Fibromuscular differentiation in deeply infiltrating endometriosis is a reaction of resident fibroblasts to the presence of ectopic endometrium
KJ Kaam, JP Schouten, AW Nap, GA Dunselman, PG Groothuis |
Human Reproduction | 2008 |
|
Antioxidants as Potential Therapeutics for Lung Fibrosis
BJ Day |
Antioxidants & Redox Signaling | 2008 |
|
Involvement of Epithelial Cell Apoptosis in Interstitial Lung Diseases
K Kuwano |
Internal Medicine | 2008 |
|
Morphological and molecular markers in idiopathic pulmonary fibrosis
F Calabrese, C Giacometti, F Lunardi, M Valente |
Expert Review of Respiratory Medicine | 2008 |
|
The Immunobiology of Systemic Sclerosis
YS Gu, J Kong, GS Cheema, CL Keen, G Wick, ME Gershwin |
Seminars in Arthritis and Rheumatism | 2008 |
|
Thoracic Endoscopy: Advances in Interventional Pulmonology
RJ Kruklitis, DH Sterman |
Thoracic Endoscopy: Advances in Interventional Pulmonology | 2008 |
|
Comparison between conventional and "clinical" assessment of experimental lung fibrosis
K Ask, R Labiris, L Farkas, A Moeller, A Froese, T Farncombe, GB McClelland, M Inman, J Gauldie, MR Kolb |
Journal of Translational Medicine | 2008 |
|
TGF-β1 as a therapeutic target for pulmonary fibrosis and COPD
HR Kang, JY Lee, CG Lee |
Expert Review of Clinical Pharmacology | 2008 |
|
Mechanisms of wound healing responses in lupus-prone New Zealand White mouse strain
PP Campos, YS Bakhle, SP Andrade |
Wound Repair and Regeneration | 2008 |
|
Dual Action of TGF-β1 on Nasal-Polyp Derived Fibroblasts
SC Little, SB Early, CR Woodard, DC Shonka, JK Han, L Borish, JW Steinke |
The Laryngoscope | 2008 |
|
Effect of infliximab on the levels of TNF-α and TGF-β in the whole blood cultures of irradiated patients
E Staroslawska, KJ Czarnocki, M Koziol-Montewka, H Donica, A Magrys |
Folia Histochemica et Cytobiologica | 2008 |
|
The Latent Form of TGFβ1is Induced by TNFα Through an ERK Specific Pathway and is Activated by Asbestos-Derived Reactive Oxygen SpeciesIn VitroandIn Vivo
DE Sullivan, MB Ferris, D Pociask, AR Brody |
Journal of Immunotoxicology | 2008 |
|
Identification of Transforming Growth Factor β1–Driven Genetic Programs of Acute Lung Fibrosis
AM Pulichino, IM Wang, A Caron, J Mortimer, A Auger, Y Boie, JA Elias, A Kartono, L Xu, J Menetski, CE Sayegh |
American journal of respiratory cell and molecular biology | 2008 |
|
Transforming Growth Factor-β Regulates House Dust Mite–induced Allergic Airway Inflammation but Not Airway Remodeling
R Fattouh, NG Midence, K Arias, JR Johnson, TD Walker, S Goncharova, KP Souza, RC Gregory, S Lonning, J Gauldie, M Jordana |
American journal of respiratory and critical care medicine | 2008 |
|
Pirfenidone inhibits the expression of HSP47 in TGF-β1-stimulated human lung fibroblasts
S Nakayama, H Mukae, N Sakamoto, T Kakugawa, S Yoshioka, H Soda, H Oku, Y Urata, T Kondo, H Kubota, K Nagata, S Kohno |
Life Sciences | 2008 |
|
Metabolomics in Lung Inflammation:A High-Resolution 1 H NMR Study of Mice Exposedto Silica Dust
JZ Hu, DN Rommereim, KR Minard, A Woodstock, BJ Harrer, RA Wind, RP Phipps, PJ Sime |
Toxicology Mechanisms and Methods | 2008 |
|
Transforming Growth Factor-β1 Induces Heparan Sulfate 6- O -Endosulfatase 1 Expression in Vitro and in Vivo
X Yue, X Li, HT Nguyen, DR Chin, DE Sullivan, JA Lasky |
The Journal of biological chemistry | 2008 |
|
Murine models of pulmonary fibrosis
BB Moore, CM Hogaboam |
American journal of physiology. Lung cellular and molecular physiology | 2008 |
|
Animal models of pulmonary fibrosis: how far from effective reality?
J Gauldie, M Kolb |
American journal of physiology. Lung cellular and molecular physiology | 2008 |
|
ClC-3 is required for LPA-activated Cl − current activity and fibroblast-to-myofibroblast differentiation
Z Yin, Y Tong, H Zhu, MA Watsky |
American journal of physiology. Cell physiology | 2008 |
|
Protein kinase B/Akt activity is involved in renal TGF-β1-driven epithelial-mesenchymal transition in vitro and in vivo
JJ Kattla, RM Carew, M Heljić, C Godson, DP Brazil |
American journal of physiology. Renal physiology | 2008 |
|
Transforming Growth Factor-β in Cancer Therapy, Volume I
SB Jakowlew |
2008 | |
|
Molecular Pathology of Lung Diseases
DS Zander, HH Popper, J Jagirdar, AK Haque, PT Cagle, R Barrios |
2008 | |
|
Squamous metaplasia amplifies pathologic epithelial-mesenchymal interactions in COPD
Jun Araya, Stephanie Cambier,Jennifer A. Markovics, Paul Wolters, David Jablons, Arthur Hill, Walter Finkbeiner, Kirk Jones, V. Courtney Broaddus, Dean Sheppard, Andrea Barzcak, Yuanyuan Xiao, David J. Erle, Stephen L. Nishimura |
Journal of Clinical Investigation | 2007 |
|
Progressive pulmonary fibrosis is mediated by TGF-β isoform 1 but not TGF-β3
K Ask, P Bonniaud, K Maass, O Eickelberg, PJ Margetts, D Warburton, J Groffen, J Gauldie, M Kolb |
The International Journal of Biochemistry & Cell Biology | 2007 |
|
Lack of MK2 inhibits myofibroblast formation and exacerbates pulmonary fibrosis
T Liu, RR Warburton, OE Guevara, NS Hill, BL Fanburg, M Gaestel, US Kayyali |
American journal of respiratory cell and molecular biology | 2007 |
|
Inhibition of integrin alpha(v)beta6, an activator of latent transforming growth factor-beta, prevents radiation-induced lung fibrosis
K Puthawala, N Hadjiangelis, SC Jacoby, E Bayongan, Z Zhao, Z Yang, ML Devitt, GS Horan, PH Weinreb, ME Lukashev, SM Violette, KS Grant, C Colarossi, SC Formenti, JS Munger |
American journal of respiratory and critical care medicine | 2007 |
|
TGF-beta1 induces progressive pleural scarring and subpleural fibrosis
N Decologne, M Kolb, PJ Margetts, F Menetrier, Y Artur, C Garrido, J Gauldie, P Camus, P Bonniaud |
Journal of immunology (Baltimore, Md. : 1950) | 2007 |
|
Genomic profile of matrix and vasculature remodeling in TGF-alpha induced pulmonary fibrosis
WD Hardie, TR Korfhagen, MA Sartor, A Prestridge, M Medvedovic, TD le Cras, M Ikegami, SC Wesselkamper, C Davidson, M Dietsch, W Nichols, JA Whitsett, GD Leikauf |
American journal of respiratory cell and molecular biology | 2007 |
|
Molecular Targets in Pulmonary Fibrosis
CJ Scotton, RC Chambers |
Chest | 2007 |
|
αvβ6 Integrin Regulates Renal Fibrosis and Inflammation in Alport Mouse
K Hahm, ME Lukashev, Y Luo, WJ Yang, BM Dolinski, PH Weinreb, KJ Simon, LC Wang, DR Leone, RR Lobb, DJ McCrann, NE Allaire, GS Horan, A Fogo, R Kalluri, CF 3rd, D Sheppard, HA Gardner, SM Violette |
The American Journal of Pathology | 2007 |
|
Decreased asbestos-induced lung inflammation and fibrosis after radiation and bone marrow transplant
J Levis, R Loi, KJ Butnor, P Vacek, C Steele, BT Mossman, DJ Weiss |
American journal of respiratory cell and molecular biology | 2007 |
|
The Role of PPARs in Lung Fibrosis
HF Lakatos, TH Thatcher, RM Kottmann, TM Garcia, RP Phipps, PJ Sime |
PPAR Research | 2007 |
|
Current and emerging drugs for idiopathic pulmonary fibrosis
M Gharaee-Kermani, B Hu, VJ Thannickal, SH Phan, MR Gyetko |
Expert Opinion on Emerging Drugs | 2007 |
|
Effect of TGF-?/Smad signaling pathway on lung myofibroblast differentiation
L GU, Y ZHU, X YANG, ZJ GUO, W XU, X TIAN |
Acta Pharmacologica Sinica | 2007 |
|
Bronchoalveolar lavage fluid from patients with acute lung injury/acute respiratory distress syndrome induces myofibroblast differentiation
L Synenki, NS Chandel, GR Budinger, HK Donnelly, J Topin, J Eisenbart, B Jovanovic, M Jain |
Critical Care Medicine | 2007 |
|
TGF-β signaling: A tale of two responses
RA Rahimi, EB Leof |
Journal of Cellular Biochemistry | 2007 |
|
Inflammation and the Aging Process: Devil or Angel
J Gauldie |
Nutrition Reviews | 2007 |
|
TGFβ and Smad3 link inflammation to progressive fibrosis
J Gauldie, P Bonniaud, P Margetts, P Sime, K Ask, M Kolb |
International Congress Series | 2007 |
|
PGE(2) inhibition of TGF-beta1-induced myofibroblast differentiation is Smad-independent but involves cell shape and adhesion-dependent signaling
PE Thomas, M Peters-Golden, ES White, VJ Thannickal, BB Moore |
American journal of physiology. Lung cellular and molecular physiology | 2007 |
|
Inflammatory and remodeling events in asthma with chronic exposure to house dust mites: a murine model
JH Ahn, CH Kim, YH Kim, SJ Kim, SY Lee, YK Kim, KH Kim, HS Moon, JS Song, SH Park, SS Kwon |
Journal of Korean Medical Science | 2007 |
|
Adenoviral gene transfer of bioactive TGFbeta1 to the rodent eye as a novel model for anterior subcapsular cataract
JV Robertson, Z Nathu, A Najjar, D Dwivedi, J Gauldie, JA West-Mays |
Molecular vision | 2007 |
|
Association between a TGFβ1 promoter polymorphism and rhinosinusitis in aspirin-intolerant asthmatic patients
SH Kim, HS Park, JW Holloway, HD Shin, CS Park |
Respiratory Medicine | 2007 |
|
Genetic Susceptibility To Late Normal Tissue Injury
EL Travis |
Seminars in radiation oncology | 2007 |
|
Inflammatory Mediators in the Immunobiology of Bronchopulmonary Dysplasia
RM Ryan, Q Ahmed, S Lakshminrusimha |
Clinical Reviews in Allergy & Immunology | 2007 |
|
Mice lacking cystathionine beta synthase have lung fibrosis and air space enlargement
J Hamelet, N Maurin, R Fulchiron, JM Delabar, N Janel |
Experimental and Molecular Pathology | 2007 |
|
Laser capture microdissection reveals dose–response of gene expression in situ consequent to asbestos exposure
Q Yin, AR Brody, DE Sullivan |
International Journal of Experimental Pathology | 2007 |
|
IL-4 gene transfer to the small bowel serosa leads to intestinal inflammation and smooth muscle hyperresponsiveness
BA Vallance, N Radojevic, CM Hogaboam, Y Deng, J Gauldie, SM Collins |
AJP Gastrointestinal and Liver Physiology | 2007 |
|
Paclitaxel interrupts TGF-beta1 signaling between gallbladder epithelial cells and myofibroblasts
HS Choi, CE Savard, JW Choi, R Kuver, SP Lee |
The Journal of surgical research | 2007 |
|
Imbalance of Receptor-Regulated and Inhibitory Smads in Lung Fibroblasts from Bleomycin-Exposed Rats
AV Gonzalez, FL Bellego, MS Ludwig |
American journal of respiratory cell and molecular biology | 2007 |
|
PGE 2 inhibition of TGF-β1-induced myofibroblast differentiation is Smad-independent but involves cell shape and adhesion-dependent signaling
PE Thomas, M Peters-Golden, ES White, VJ Thannickal, BB Moore |
American journal of physiology. Lung cellular and molecular physiology | 2007 |
|
TGF-β-regulated collagen type I accumulation: role of Src-based signals
R Mishra, L Zhu, RL Eckert, MS Simonson |
American journal of physiology. Cell physiology | 2007 |
|
Expression of Transforming Growth Factor-β by Human Islets: Impact on Islet Viability and Function
OM Sabek, DW Fraga, J Henry, LW Gaber, M Kotb, AO Gaber |
Cell Transplantation | 2007 |
|
The Chemokine Receptors
JK Harrison, NW Lukacs |
2007 | |
|
Thalidomide Prevents Bleomycin-Induced Pulmonary Fibrosis in Mice
C Tabata, R Tabata, Y Kadokawa, S Hisamori, M Takahashi, M Mishima, T Nakano, H Kubo |
Journal of immunology (Baltimore, Md. : 1950) | 2007 |
|
Increased bleomycin-induced lung injury in mice deficient in the transcription factor T-bet
J Xu, AL Mora, J LaVoy, KL Brigham, M Rojas |
American journal of physiology. Lung cellular and molecular physiology | 2006 |
|
Caveolin-1: a critical regulator of lung fibrosis in idiopathic pulmonary fibrosis
XM Wang, Y Zhang, HP Kim, Z Zhou, CA Feghali-Bostwick, F Liu, E Ifedigbo, X Xu, TD Oury, N Kaminski, AM Choi |
Journal of Experimental Medicine | 2006 |
|
Epithelial-mesenchymal interactions in pulmonary fibrosis
JC Horowitz, VJ Thannickal |
Seminars in respiratory and critical care medicine | 2006 |
|
Microarray identifies ADAM family members as key responders to TGF-β1 in alveolar epithelial cells
DT Keating, DM Sadlier, A Patricelli, SM Smith, D Walls, JJ Egan, PP Doran |
Respiratory Research | 2006 |
|
Gene transfer of soluble transforming growth factor type II receptor by in vivo electroporation attenuates lung injury and fibrosis
M Yamada, K Kuwano, T Maeyama, M Yoshimi, N Hamada, J Fukumoto, K Egashira, K Hiasa, K Takayama, Y Nakanishi |
Journal of clinical pathology | 2006 |
|
Enhanced myofibroblastic differentiation and survival in Thy-1(-) lung fibroblasts
YY Sanders, P Kumbla, JS Hagood |
American journal of respiratory cell and molecular biology | 2006 |
|
Transgenic modeling of transforming growth factor-beta(1): role of apoptosis in fibrosis and alveolar remodeling
CG Lee, HR Kang, RJ Homer, G Chupp, JA Elias |
Proceedings of the American Thoracic Society | 2006 |
|
Proapoptotic Bid is required for pulmonary fibrosis
GR Budinger, GM Mutlu, J Eisenbart, AC Fuller, AA Bellmeyer, CM Baker, M Wilson, K Ridge, TA Barrett, VY Lee, NS Chandel |
Proceedings of the National Academy of Sciences | 2006 |
|
Obligatory Role for Interleukin-13 in Obstructive Lesion Development in Airway Allografts
VN Lama, H Harada, LN Badri, A Flint, CM Hogaboam, A McKenzie, FJ Martinez, GB Toews, BB Moore, DJ Pinsky |
The American Journal of Pathology | 2006 |
|
Smad3 signaling involved in pulmonary fibrosis and emphysema
J Gauldie, M Kolb, K Ask, G Martin, P Bonniaud, D Warburton |
Proceedings of the American Thoracic Society | 2006 |
|
EM703 improves bleomycin-induced pulmonary fibrosis in mice by the inhibition of TGF-β signaling in lung fibroblasts
YJ Li, A Azuma, J Usuki, S Abe, K Matsuda, T Sunazuka, T Shimizu, Y Hirata, H Inagaki, T Kawada, S Takahashi, S Kudoh, S Omura |
Respiratory Research | 2006 |
|
Macrophage metalloelastase (MMP-12) deficiency does not alter bleomycin-induced pulmonary fibrosis in mice
B Manoury, S Nenan, I Guenon, E Boichot, JM Planquois, CP Bertrand, V Lagente |
Journal of Inflammation | 2006 |
|
Epithelial origin of myofibroblasts during fibrosis in the lung
BC Willis, RM duBois, Z Borok |
Proceedings of the American Thoracic Society | 2006 |
|
Angelica sinensis Down-regulates Hydroxyproline and Tgfb1 and Provides Protection in Mice with Radiation-Induced Pulmonary Fibrosis
G Han, YF Zhou, MS Zhang, Z Cao, CH Xie, FX Zhou, M Peng, WJ Zhang |
Radiation Research | 2006 |
|
Idiopathic Pulmonary Fibrosis
JC Horowitz, VJ Thannickal |
Treatments in Respiratory Medicine | 2006 |
|
Therapeutic strategies against TGF-beta signaling pathway in hepatic fibrosis
X Liu, H Hu, JQ Yin |
Liver International | 2006 |
|
Differenzielle Therapie bei Lungenfibrosen
P Markart, W Seeger, A Günther |
Der Internist | 2006 |
|
Role of Extracellular Signal-Regulated Kinase, p38 Kinase, and Activator Protein-1 in Transforming Growth Factor-β1–Induced Alpha Smooth Muscle Actin Expression in Human Fetal Lung Fibroblasts In Vitro
Y Hu, J Peng, D Feng, L Chu, X Li, Z Jin, Z Lin, Q Zeng |
Lung | 2006 |
|
IN-1130, a novel transforming growth factor-β type I receptor kinase (ALK5) inhibitor, suppresses renal fibrosis in obstructive nephropathy
JA Moon, HT Kim, IS Cho, YY Sheen, DK Kim |
Kidney International | 2006 |
|
Models of pulmonary fibrosis
A Moeller, JC Rodriguez-Lecompte, L Wang, J Gauldie, M Kolb |
Drug Discovery Today: Disease Models | 2006 |
|
The transforming growth factor-beta (TGF-β) family and pulmonary fibrosis
GE Martin, K Ask, SE Gilpin, M Kolb, J Gauldie |
Drug Discovery Today: Disease Mechanisms | 2006 |
|
Growth factors in pleural fibrosis
SE Mutsaers, I Kalomenidis, NA Wilson, YC Lee |
Current Opinion in Pulmonary Medicine | 2006 |
|
TGFβ1 regulates the inflammatory response during chronic neurodegeneration
D Boche, C Cunningham, F Docagne, H Scott, VH Perry |
Neurobiology of Disease | 2006 |
|
Integrin-mediated transforming growth factor-beta activation regulates homeostasis of the pulmonary epithelial-mesenchymal trophic unit
J Araya, S Cambier, A Morris, W Finkbeiner, SL Nishimura |
The American Journal of Pathology | 2006 |
|
Receptor-activated Smad localisation in bleomycin-induced pulmonary fibrosis
H Higashiyama, D Yoshimoto, Y Okamoto, H Kikkawa, S Asano, M Kinoshita |
Journal of clinical pathology | 2006 |
|
Idiopathic pulmonary fibrosis : new concepts in pathogenesis and implications for drug therapy
JC Horowitz, VJ Thannickal |
Treatments in Respiratory Medicine | 2006 |
|
Anti-fibrotic effects of theophylline on lung fibroblasts
Y Yano, M Yoshida, S Hoshino, K Inoue, H Kida, M Yanagita, T Takimoto, H Hirata, T Kijima, T Kumagai, T Osaki, I Tachibana, I Kawase |
Biochemical and Biophysical Research Communications | 2006 |
|
Thrombospondin 1 mediates angiotensin II induction of TGF-β activation by cardiac and renal cells under both high and low glucose conditions
Y Zhou, MH Poczatek, KH Berecek, JE Murphy-Ullrich |
Biochemical and Biophysical Research Communications | 2006 |
|
Use of recombinant virus-vectored tuberculosis vaccines for respiratory mucosal immunization
Z Xing, BD Lichty |
Tuberculosis | 2006 |
|
RUTI: A new chance to shorten the treatment of latent tuberculosis infection
PJ Cardona |
Tuberculosis | 2006 |
|
Idiopathic Pulmonary Fibrosis: New Concepts in Pathogenesis and Implications for Drug Therapy
JC Horowitz, VJ Thannickal |
Treatments in Respiratory Medicine | 2006 |
|
Gene expression of cytokines and growth factors in the lungs after paraquat administration in mice
Y Ishida, T Takayasu, A Kimura, T Hayashi, N Kakimoto, T Miyashita, T Kondo |
Legal Medicine | 2006 |
|
Cell-specific Gene Expression in Patients with Usual Interstitial Pneumonia
MM Kelly, R Leigh, SE Gilpin, E Cheng, GE Martin, K Radford, G Cox, J Gauldie |
American journal of respiratory and critical care medicine | 2006 |
|
Role of Eosinophil Chemotactic Factor by T Lymphocytes on Airway Hyperresponsiveness in a Murine Model of Allergic Asthma
H Iwashita, S Morita, Y Sagiya, A Nakanishi |
American journal of respiratory cell and molecular biology | 2006 |
|
Encyclopedia of Respiratory Medicine
PD Wagner |
Encyclopedia of Respiratory Medicine | 2006 |
|
Pulmonary cytomegalovirus reactivation causes pathology in immunocompetent mice*:
CH Cook, Y Zhang, DD Sedmak, LC Martin, S Jewell, RM Ferguson |
Critical Care Medicine | 2006 |
|
Particle Toxicology: TNF-_ and TGF-_1 as Mediators of Asbestos-Induced Lung Fibrogenesis
A Brody, D Sullivan |
Particle Toxicology: TNF-_ and TGF-_1 as Mediators of Asbestos-Induced Lung Fibrogenesis | 2006 |
|
Transforming growth factor-β 1 -induced endothelial barrier dysfunction involves Smad2-dependent p38 activation and subsequent RhoA activation
Q Lu, EO Harrington, H Jackson, N Morin, C Shannon, S Rounds |
Journal of applied physiology | 2006 |
|
Prostacyclin agonist with thromboxane synthase inhibitory activity (ONO-1301) attenuates bleomycin-induced pulmonary fibrosis in mice
S Murakami, N Nagaya, T Itoh, M Kataoka, T Iwase, T Horio, Y Miyahara, Y Sakai, K Kangawa, H Kimura |
American journal of physiology. Lung cellular and molecular physiology | 2006 |
|
Analysis of the bovine neutrophil transcriptome during glucocorticoid treatment
PS Weber, SA Madsen-Bouterse, GJ Rosa, S Sipkovsky, X Ren, PE Almeida, R Kruska, RG Halgren, JL Barrick, JL Burton |
Physiological genomics | 2006 |
|
Pulmonary Emphysema: When More is Less
DG Morris, D Sheppard |
Physiology (Bethesda, Md.) | 2006 |
|
Dominant negative mutation of the TGF-β receptor blocks hypoxia-induced pulmonary vascular remodeling
YF Chen, JA Feng, P Li, D Xing, Y Zhang, R Serra, N Ambalavanan, E Majid-Hassan, S Oparil |
Journal of applied physiology | 2006 |
|
FAK-dependent regulation of myofibroblast differentiation
RS Greenberg, AM Bernstein, M Benezra, IH Gelman, L Taliana, SK Masur |
The FASEB Journal | 2006 |
|
Effect of Transforming Growth Factor-β Receptor I Kinase Inhibitor 2,4-Disubstituted Pteridine (SD-208) in Chronic Allergic Airway Inflammation and Remodeling
SY Leung, A Niimi, A Noble, T Oates, AS Williams, S Medicherla, AA Protter, KF Chung |
The Journal of pharmacology and experimental therapeutics | 2006 |
|
Adenovirus-Based Transient Expression Systems for Peritoneal Membrane Research
CM Hoff, PJ Margetts |
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis | 2006 |
|
The Future of Antisense Oligonucleotides in the Treatment of Respiratory Diseases:
M Ulanova, AD Schreiber, AD Befus |
BioDrugs | 2006 |
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Prevention of chronic allograft nephropathy with vitamin D
DA Hullett, PF Laeseke, G Malin, R Nessel, HW Sollinger, BN Becker |
Transplant International | 2005 |
|
Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis
BC Willis, JM Liebler, K Luby-Phelps, AG Nicholson, ED Crandall, RM du Bois, Z Borok |
The American Journal of Pathology | 2005 |
|
TGF-beta and Smad3 signaling link inflammation to chronic fibrogenesis
P Bonniaud, PJ Margetts, K Ask, K Flanders, J Gauldie, M Kolb |
Journal of immunology (Baltimore, Md. : 1950) | 2005 |
|
Modulation of Prosurvival Signaling in Fibroblasts by a Protein Kinase Inhibitor Protects against Fibrotic Tissue Injury
R Vittal, JC Horowitz, BB Moore, H Zhang, FJ Martinez, GB Toews, TJ Standiford, VJ Thannickal |
The American Journal of Pathology | 2005 |
|
Developmental regulation and coordinate reexpression of FKBP65 with extracellular matrix proteins after lung injury suggest a specialized function for this endoplasmic reticulum immunophilin
CE Patterson, WR Abrams, NE Wolter, J Rosenbloom, EC Davis |
Cell stress & chaperones | 2005 |
|
Adenosine-Dependent Pulmonary Fibrosis in Adenosine Deaminase-Deficient Mice
JL Chunn, JG Molina, T Mi, Y Xia, RE Kellems, MR Blackburn |
Journal of immunology (Baltimore, Md. : 1950) | 2005 |
|
Growth, phenotype, and function of human intestinal mast cells are tightly regulated by transforming growth factor beta1
T Gebhardt, A Lorentz, F Detmer, C Trautwein, H Bektas, MP Manns, SC Bischoff |
Gut | 2005 |
|
Partially adenosine deaminase-deficient mice develop pulmonary fibrosis in association with adenosine elevations
JL Chunn |
American journal of physiology. Lung cellular and molecular physiology | 2005 |
|
LUNG VASCULAR DEVELOPMENT: Implications for the Pathogenesis of Bronchopulmonary Dysplasia
KR Stenmark, SH Abman |
Annual Review of Physiology | 2005 |
|
Different Effects of Growth Factors on Proliferation and Matrix Production of Normal and Fibrotic Human Lung Fibroblasts
M Hetzel, M Bachem, D Anders, G Trischler, M Faehling |
Lung | 2005 |
|
Emerging drugs for idiopathic pulmonary fibrosis
VJ Thannickal, KR Flaherty, RC Hyzy, JP 3rd |
Expert Opinion on Emerging Drugs | 2005 |
|
Similarities and dissimilarities of branching and septation during lung development
M Roth-Kleiner, M Post |
Pediatric Pulmonology | 2005 |
|
Engineered E. coli delivers therapeutic genes to the colonic mucosa
I Castagliuolo, E Beggiao, P Brun, L Barzon, S Goussard, R Manganelli, C Grillot-Courvalin, G Palù |
Gene Therapy | 2005 |
|
Pediatric lung disease: From proteinases to pulmonary fibrosis
F Chua, PD Sly, GJ Laurent |
Pediatric Pulmonology | 2005 |
|
Molecular Mechanisms of Early Lung Specification and Branching Morphogenesis
D Warburton, S Bellusci, SD Langhe, PM Moral, V Fleury, A Mailleux, D Tefft, M Unbekandt, K Wang, W Shi |
Pediatric Research | 2005 |
|
Pathophysiological effects of glucocorticoids on nasal polyps: an update
M Benson |
Current Opinion in Allergy and Clinical Immunology | 2005 |
|
Amino Acid Requirements for Formation of the TGF-β-Latent TGF-β Binding Protein Complexes
Y Chen, T Ali, V Todorovic, JM O'Leary, AK Downing, DB Rifkin |
Journal of Molecular Biology | 2005 |
|
Decorin and biglycan expression is differentially altered in several muscular dystrophies
S Zanotti, T Negri, C Cappelletti, P Bernasconi, E Canioni, CD Blasi, E Pegoraro, C Angelini, P Ciscato, A Prelle, R Mantegazza, L Morandi, M Mora |
Brain | 2005 |
|
Pulmonary fibrosis
DA Zisman, MP Keane, JA Belperio, RM Strieter, JP 3rd |
Methods in molecular medicine | 2005 |
|
Inhalation Toxicology, Second Edition
M Blackwell |
Inhalation Toxicology, Second Edition | 2005 |
|
Pulmonary Fibrosis: Searching for Model Answers
F Chua, J Gauldie, GJ Laurent |
American journal of respiratory cell and molecular biology | 2005 |
|
Tumor Necrosis Factor-α Induces Transforming Growth Factor-β 1 Expression in Lung Fibroblasts Through the Extracellular Signal–Regulated Kinase Pathway
DE Sullivan, MB Ferris, D Pociask, AR Brody |
American journal of respiratory cell and molecular biology | 2005 |
|
Attenuation of Bleomycin-induced Pulmonary Fibrosis by Follistatin
F Aoki, M Kurabayashi, Y Hasegawa, I Kojima |
American journal of respiratory and critical care medicine | 2005 |
|
Le Transforming Growth Factor-beta (TGF-β) : une cytokine de plus en plus impliquée dans la physiopathogénie des maladies pulmonaires, fibroses en particulier
A Sauty, JD Aubert |
Revue des Maladies Respiratoires | 2005 |
|
Elevated formation of pyridinoline cross-links by profibrotic cytokines is associated with enhanced lysyl hydroxylase 2b levels
AJ van der Slot, EA van Dura, EC de Wit, J DeGroot, TW Huizinga, RA Bank, AM Zuurmond |
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2005 |
|
TGF-β1 induces human alveolar epithelial to mesenchymal cell transition (EMT)
H Kasai, JT Allen, RM Mason, T Kamimura, Z Zhang |
Respiratory Research | 2005 |
|
Caffeic acid phenethyl ester decreases acute pneumonitis after irradiation in vitro and in vivo
MF Chen, PC Keng, PY Lin, CT Yang, SK Liao, WC Chen |
BMC Cancer | 2005 |
|
Pulmonary overexpression of IL-10 augments lung fibrosis and Th2 responses induced by silica particles
V Barbarin, Z Xing, M Delos, D Lison, F Huaux |
American journal of physiology. Lung cellular and molecular physiology | 2005 |
|
TGF-β1 gene transfer to the mouse colon leads to intestinal fibrosis
BA Vallance, MI Gunawan, B Hewlett, P Bercik, CV Kampen, F Galeazzi, PJ Sime, J Gauldie, SM Collins |
AJP Gastrointestinal and Liver Physiology | 2005 |
|
Crystalline and amorphous silica differentially regulate the cyclooxygenase-prostaglandin pathway in pulmonary fibroblasts: implications for pulmonary fibrosis
KM O'Reilly, RP Phipps, TH Thatcher, BA Graf, JV Kirk, PJ Sime |
American journal of physiology. Lung cellular and molecular physiology | 2005 |
|
RhoA and Rho-kinase dependent and independent signals mediate TGF-β-induced pulmonary endothelial cytoskeletal reorganization and permeability
RT Clements, FL Minnear, HA Singer, RS Keller, PA Vincent |
American journal of physiology. Lung cellular and molecular physiology | 2005 |
|
The gene transfer of soluble VEGF type I receptor (Flt-1) attenuates peritoneal fibrosis formation in mice but not soluble TGF-β type II receptor gene transfer
Y Motomura, H Kanbayashi, WI Khan, Y Deng, PA Blennerhassett, PJ Margetts, J Gauldie, K Egashira, SM Collins |
AJP Gastrointestinal and Liver Physiology | 2005 |
|
PPARγ agonists inhibit TGF-β induced pulmonary myofibroblast differentiation and collagen production: implications for therapy of lung fibrosis
HA Burgess, LE Daugherty, TH Thatcher, HF Lakatos, DM Ray, M Redonnet, RP Phipps, PJ Sime |
American journal of physiology. Lung cellular and molecular physiology | 2005 |
|
Chloride channel activity in human lung fibroblasts and myofibroblasts
Z Yin, MA Watsky |
American journal of physiology. Lung cellular and molecular physiology | 2005 |
|
Malignant Mesothelioma
HI Pass, NJ Vogelzang, M Carbone |
2005 | |
|
Cell Engineering
M Al-Rubeai, M Fussenegger |
2005 | |
|
Manipulation of Allergen-Induced Airway Remodeling by Treatment with Anti-TGF-β Antibody: Effect on the Smad Signaling Pathway
SJ McMillan, G Xanthou, CM Lloyd |
Journal of immunology (Baltimore, Md. : 1950) | 2005 |
|
Crystalline and Amorphous Silica Differentially Regulate the Cyclooxygenase-Prostaglandin Pathway in Pulmonary Fibroblasts: Implications for Pulmonary Fibrosis
O\u2019Reilly KM, Phipps RP, Thatcher TH, Graf BA, Van Kirk J, Sime PJ |
American journal of physiology. Lung cellular and molecular physiology | 2005 |
|
Imatinib Mesylate Inhibits the Pro-fibrogenic Activity of TGF-beta and Prevents Bleomycin-mediated Lung Fibrosis
Craig E. Daniels, Mark C. Wilkes, Maryanne Edens, Ted J. Kottom, Stephen J. Murphy, Andrew H. Limper, Edward B. Leof |
Journal of Clinical Investigation | 2004 |
|
Thrombospondin-1 is a major activator of TGF-beta in fibrotic renal disease in the rat in vivo
C Daniel, J Wiede, HC Krutzsch, SM Ribeiro, DD Roberts, JE Murphy-Ullrich, C Hugo |
Kidney International | 2004 |
|
Intrapleural injection of transforming growth factor-beta antibody inhibits pleural fibrosis in empyema
CR Kunz, MR Jadus, GD Kukes, F Kramer, VN Nguyen, SA Sasse |
Chest | 2004 |
|
Smad3 null mice develop airspace enlargement and are resistant to TGF-beta-mediated pulmonary fibrosis
P Bonniaud, M Kolb, T Galt, J Robertson, C Robbins, M Stampfli, C Lavery, PJ Margetts, AB Roberts, J Gauldie |
Journal of immunology (Baltimore, Md. : 1950) | 2004 |
|
Early Growth Response Gene 1–mediated Apoptosis Is Essential for Transforming Growth Factor β 1 –induced Pulmonary Fibrosis
CG Lee, SJ Cho, MJ Kang, SP Chapoval, PJ Lee, PW Noble, T Yehualaeshet, B Lu, RA Flavell, J Milbrandt, RJ Homer, JA Elias |
Journal of Experimental Medicine | 2004 |
|
Attenuation of bleomycin induced pulmonary fibrosis in mice using the heme oxygenase inhibitor Zn-deuteroporphyrin IX-2,4-bisethylene glycol
L Atzori, F Chua, SE Dunsmore, D Willis, M Barbarisi, RJ McAnulty, GJ Laurent |
Thorax | 2004 |
|
Fibrotic disease and the TH1/TH2 paradigm
TA Wynn |
Nature Reviews Immunology | 2004 |
|
Transforming growth factor-beta facilitates breast carcinoma metastasis by promoting tumor cell survival
Q Yu, I Stamenkovic |
Clinical & Experimental Metastasis | 2004 |
|
Lung fibroblast clones from normal and fibrotic subjects differ in hyaluronan and decorin production and rate of proliferation
G Westergren-Thorsson, P Sime, M Jordana, J Gauldie, B Särnstrand, A Malmström |
The International Journal of Biochemistry & Cell Biology | 2004 |
|
Idiopathic pulmonary fibrosis: emerging concepts on pharmacotherapy
VJ Thannickal, KR Flaherty, FJ Martinez, JP 3rd |
Expert Opinion on Pharmacotherapy | 2004 |
|
Asbestos-derived reactive oxygen species activate TGF-β1
DA Pociask, PJ Sime, AR Brody |
Laboratory Investigation | 2004 |
|
Transforming growth factor β1 induction of Tissue Inhibitor of MetalloProteinases 3 in articular chondrocytes is mediated by reactive oxygen species
WQ Li, HY Qureshi, A Liacini, F Dehnade, M Zafarullah |
Free radical biology & medicine | 2004 |
|
Thy-1 Expression Regulates the Ability of Rat Lung Fibroblasts to Activate Transforming Growth Factor-β in Response to Fibrogenic Stimuli
Y Zhou, JS Hagood, JE Murphy-Ullrich |
The American Journal of Pathology | 2004 |
|
Prevention of fibrosis in experimental colitis by captopril: The role of tgf-β1
D Wengrower, G Zannineli, O Pappo, G Latella, M Sestieri, A Villanova, Y Faitelson, M Pines, E Goldin |
Inflammatory Bowel Diseases | 2004 |
|
Leukotriene D4 stimulates collagen production from myofibroblasts transformed by TGF-β
T Asakura, Y Ishii, K Chibana, T Fukuda |
Journal of Allergy and Clinical Immunology | 2004 |
|
Thy-1 expression regulates the ability of rat lung fibroblasts to activate transforming growth factor-beta in response to fibrogenic stimuli
Y Zhou, JS Hagood, JE Murphy-Ullrich |
The American Journal of Pathology | 2004 |
|
Idiopathic pulmonary fibrosis: new insights into pathogenesis
PW Noble, RJ Homer |
Clinics in Chest Medicine | 2004 |
|
Transplantation of islets transduced with CTLA4-Ig and TGFβ using adenovirus and lentivirus vectors
JR Fernandes, VF Duvivier-Kali, M Keegan, J Hollister-Lock, A Omer, S Su, S Bonner-Weir, S Feng, JS Lee, RC Mulligan, GC Weir |
Transplant Immunology | 2004 |
|
The Lung
KH Albertine, TJ Psysher |
The Lung | 2004 |
|
Principles of Gender-Specific Medicine
G Supinski, LA Callahan |
Principles of Gender-Specific Medicine | 2004 |
|
Lung Biology in Health and Disease: Past, Present and Future
R Kruklitis, D Sterman |
Lung Biology in Health and Disease: Experimental Models and Therapeutic Potential | 2004 |
|
Functional Genomics of Lung Disease
JA Whitsett, CJ Bachurski, KC Barnes, PA Bunn, LM Case, DN Cook, D Crooks, MW Duncan, L Dwyer-Nield, RC Elston, MB Fessler, WA Franklin, N Friedman, JG Garcia, MW Geraci, C Glasgow, SW Glasser, WD Hardie, LM Henning, GL Johnson, K Kawkitinarong, RL Keith, TR Korfhagen, GD Leikauf, SB Liggett, KC Malcolm, AM Malkinson, TJ Mariani, SA McDowell, DW McGraw, M Medvedovic, J Moss, LM Nogee, S Nonas, G Pacheco-Rodriguez, LJ Palmer, DG Peters, DR Prows, S Redline, A Regev, MA Sartor, DA Schwartz, EK Silverman, WK Steagall, RS Stearman, A Taveira-DaSilva, JW Tichelaar, CR Tomlinson, K Tsukada, TE Weaver, SE Wert, SC Wesselkamper, GS Worthen, Y Xu, L Zerbe, Y Zhang, Y Zhang, AM Choi, N Kaminski |
American journal of respiratory cell and molecular biology | 2004 |
|
The molecular genetics of lung morphogenesis and injury repair
D Warburton, S Bellusci |
Paediatric Respiratory Reviews | 2004 |
|
Conditional Overexpression of Bioactive Transforming Growth Factor–β1 in Neonatal Mouse Lung: A New Model for Bronchopulmonary Dysplasia?
AG Vicencio, CG Lee, SJ Cho, O Eickelberg, Y Chuu, GG Haddad, JA Elias |
American journal of respiratory cell and molecular biology | 2004 |
|
The mechanisms of idiopathic pulmonary fibrosis: can we see the elephant?
K Gibson, N Kaminski |
Drug Discovery Today: Disease Mechanisms | 2004 |
|
Transforming Growth Factor-β 1 Promoter Polymorphism C–509T Is Associated with Asthma
ES Silverman, LJ Palmer, V Subramaniam, A Hallock, S Mathew, J Vallone, DS Faffe, T Shikanai, BA Raby, ST Weiss, SA Shore |
American journal of respiratory and critical care medicine | 2004 |
|
T Cell–specific Ablation of Fas Leads to Fas Ligand–mediated Lymphocyte Depletion and Inflammatory Pulmonary Fibrosis
Z Hao, B Hampel, H Yagita, K Rajewsky |
Journal of Experimental Medicine | 2004 |
|
Gene expression profiling reveals novel TGFβ targets in adult lung fibroblasts
EA Renzoni, DJ Abraham, S Howat, X Shi-Wen, P Sestini, G Bou-Gharios, AU Wells, S Veeraraghavan, AG Nicholson, CP Denton, A Leask, JD Pearson, CM Black, KI Welsh, RM du Bois |
Respiratory Research | 2004 |
|
Changes in Smad expression and subcellular localization in bleomycin-induced pulmonary fibrosis
N Venkatesan, L Pini, MS Ludwig |
American journal of physiology. Lung cellular and molecular physiology | 2004 |
|
Conditional expression of transforming growth factor-α in adult mouse lung causes pulmonary fibrosis
WD Hardie, TD le Cras, K Jiang, JW Tichelaar, M Azhar, TR Korfhagen |
American journal of physiology. Lung cellular and molecular physiology | 2004 |
|
Idiopathic Interstitial Lung Disease: A Review of Recent Classifications
JT Chapman, CF Farver |
Clinical Pulmonary Medicine | 2004 |
|
Protection from Fluorescein Isothiocyanate-Induced Fibrosis in IL-13-Deficient, but Not IL-4-Deficient, Mice Results from Impaired Collagen Synthesis by Fibroblasts
JE Kolodsick, GB Toews, C Jakubzick, C Hogaboam, TA Moore, A McKenzie, CA Wilke, CJ Chrisman, BB Moore |
Journal of immunology (Baltimore, Md. : 1950) | 2004 |
|
Eosinophils and T lymphocytes possess distinct roles in bleomycin-induced lung injury and fibrosis
F Huaux, T Liu, B McGarry, M Ullenbruch, Z Xing, SH Phan |
Journal of immunology (Baltimore, Md. : 1950) | 2003 |
|
Dual Roles of IL-4 in Lung Injury and Fibrosis
F Huaux, T Liu, B McGarry, M Ullenbruch, SH Phan |
Journal of immunology (Baltimore, Md. : 1950) | 2003 |
|
Transfer of the active form of transforming growth factor-beta 1 gene to newborn rat lung induces changes consistent with bronchopulmonary dysplasia.
Gauldie J, Galt T, Bonniaud P, Robbins C, Kelly M, Warburton D |
The American Journal of Pathology | 2003 |
|
Antisense Oligonucleotides Against Thrombospondin-1 Inhibit Activation of TGF-β in Fibrotic Renal Disease in the Rat in Vivo
C Daniel, Y Takabatake, M Mizui, Y Isaka, H Kawashi, H Rupprecht, E Imai, C Hugo |
The American Journal of Pathology | 2003 |
|
TGF-β1-mediated fibroblast–myofibroblast terminal differentiation—the role of smad proteins
RA Evans, YC Tian, R Steadman, AO Phillips |
Experimental Cell Research | 2003 |
|
Ex vivo gene therapy with adenovirus-mediated transforming growth factor β1 expression for endovascular treatment of aneurysm: results in a canine bilateral aneurysm model
E Ribourtout, AC Desfaits, I Salazkin, J Raymond |
Journal of Vascular Surgery | 2003 |
|
Transforming Growth Factor-??1-Mediated Neuroprotection Against Excitotoxic Injury in Vivo
D Boche, C Cunningham, J Gauldie, VH Perry |
Journal of Cerebral Blood Flow & Metabolism | 2003 |
|
Impact of Interleukin-13 Responsiveness on the Synthetic and Proliferative Properties of Th1- and Th2-Type Pulmonary Granuloma Fibroblasts
C Jakubzick, ES Choi, SL Kunkel, BH Joshi, RK Puri, CM Hogaboam |
The American Journal of Pathology | 2003 |
|
Transfer of the Active Form of Transforming Growth Factor-β1 Gene to Newborn Rat Lung Induces Changes Consistent with Bronchopulmonary Dysplasia
J Gauldie, T Galt, P Bonniaud, C Robbins, M Kelly, D Warburton |
The American Journal of Pathology | 2003 |
|
Global expression profiling of fibroblast responses to transforming growth factor-beta1 reveals the induction of inhibitor of differentiation-1 and provides evidence of smooth muscle cell phenotypic switching
RC Chambers, P Leoni, N Kaminski, GJ Laurent, RA Heller |
The American Journal of Pathology | 2003 |
|
Antisense oligonucleotides against thrombospondin-1 inhibit activation of tgf-beta in fibrotic renal disease in the rat in vivo
C Daniel, Y Takabatake, M Mizui, Y Isaka, H Kawashi, H Rupprecht, E Imai, C Hugo |
The American Journal of Pathology | 2003 |
|
Growth factor signaling in lung morphogenetic centers: automaticity, stereotypy and symmetry
D Warburton, S Bellusci, PM Moral, V Kaartinen, M Lee, D Tefft, W Shi |
Respiratory Research | 2003 |
|
The thrombospondin 1-TGF- axis in fibrotic renal disease
C Hugo |
Nephrology Dialysis Transplantation | 2003 |
|
Impact of intranasal budesonide on immune inflammatory responses and epithelial remodeling in chronic upper airway inflammation
C Mastruzzo, LR Greco, K Nakano, A Nakano, F Palermo, MP Pistorio, ET Salinaro, M Jordana, J Dolovich, N Crimi, C Vancheri |
Journal of Allergy and Clinical Immunology | 2003 |
|
Interferon Gamma-1b Therapy for Advanced Idiopathic Pulmonary Fibrosis
S Kalra, JP Utz, JH Ryu |
Mayo Clinic Proceedings | 2003 |
|
Lung Biology in Health and Disease
N Zamel |
Lung Biology in Health and Disease: Experimental Models and Therapeutic Potential | 2003 |
|
Morphometric Analysis of Mouse Airways After Chronic Allergen Challenge
R Ellis, R Leigh, D Southam, PM O'Byrne, MD Inman |
Laboratory Investigation | 2003 |
|
Induction of Regulated upon Activation, Normal T Cells Expressed and Secreted (RANTES) and Transforming Growth Factor-β1 in Airway Epithelial Cells by Mycoplasma pneumoniae
A Dakhama, M Kraft, RJ Martin, EW Gelfand |
American journal of respiratory cell and molecular biology | 2003 |
|
P-selectin inhibition decreases post-thrombotic vein wall fibrosis in a rat model
P Thanaporn, DD Myers, SK Wrobleski, AE Hawley, DM Farris, TW Wakefield, PK Henke |
Surgery | 2003 |
|
Plunging into the Chaos of the Cytokine/Chemokine Cocktail in Pulmonary Fibrosis: How Many and How Important Are They?
M Selman |
American journal of respiratory and critical care medicine | 2003 |
|
Inflammation in idiopathic pulmonary fibrosis
PF Piguet |
American journal of respiratory and critical care medicine | 2003 |
|
Activation of Transforming Growth Factor β by Malaria Parasite-derived Metalloproteinases and a Thrombospondin-like Molecule
FM Omer, JB de Souza, PH Corran, AA Sultan, EM Riley |
Journal of Experimental Medicine | 2003 |
|
Transforming Growth Factor (TGF)-β1–producing Regulatory T Cells Induce Smad-mediated Interleukin 10 Secretion That Facilitates Coordinated Immunoregulatory Activity and Amelioration of TGF-β1–mediated Fibrosis
A Kitani, I Fuss, K Nakamura, F Kumaki, T Usui, W Strober |
Journal of Experimental Medicine | 2003 |
|
Gene transfer approaches for the treatment of inflammatory bowel disease
S Wirtz, MF Neurath |
Gene Therapy | 2003 |
|
Transforming growth factor-β induces fibrosis in immune cell-depleted lungs
MA Olman, MA Matthay |
American journal of physiology. Lung cellular and molecular physiology | 2003 |
|
Release of biologically active TGF-β1 by alveolar epithelial cells results in pulmonary fibrosis
YD Xu, J Hua, A Mui, R O'Connor, G Grotendorst, N Khalil |
American journal of physiology. Lung cellular and molecular physiology | 2003 |
|
Lymphocytes endowed with colon-selective homing and engineered to produce TGF-??1 prevent the development of dinitrobenzene sulphonic acid colitis:
I Castagliuolo, P Brun, D Tormen, G Pal |
European Journal of Gastroenterology & Hepatology | 2003 |
|
Myofibroblast Differentiation by Transforming Growth Factor-β1 Is Dependent on Cell Adhesion and Integrin Signaling via Focal Adhesion Kinase
VJ Thannickal, DY Lee, ES White, Z Cui, JM Larios, R Chacon, JC Horowitz, RM Day, PE Thomas |
The Journal of biological chemistry | 2003 |
|
Hearing and hair cells are protected by adenoviral gene therapy with TGF-β1 and GDNF
K Kawamoto, M Yagi, T Stöver, S Kanzaki, Y Raphael |
Molecular Therapy | 2003 |
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Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice
J Zhao, W Shi, YL Wang, H Chen, P Bringas, MB Datto, JP Frederick, XF Wang, D Warburton |
American journal of physiology. Lung cellular and molecular physiology | 2002 |
|
Titration of non-replicating adenovirus as a vector for transducing active TGF-β1 gene expression causing inflammation and fibrogenesis in the lungs of C57BL/6 mice
GS Warshamana, DA Pociask, KJ Fisher, JY Liu, PJ Sime, AR Brody |
International Journal of Experimental Pathology | 2002 |
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Future Research Directions in Idiopathic Pulmonary Fibrosis: Summary of a National Heart, Lung, and Blood Institute Working Group
RG Crystal, PB Bitterman, B Mossman, MI Schwarz, D Sheppard, L Almasy, HA Chapman, SL Friedman, TE King, LA Leinwand, L Liotta, GR Martin, DA Schwartz, GS Schultz, CR Wagner, RA Musson |
American journal of respiratory and critical care medicine | 2002 |
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Latent and Active Transforming Growth Factor beta1 Released from Genetically Modified Keratinocytes Modulates Extracellular Matrix Expression by Dermal Fibroblasts in a Coculture System
BS Bauer, EE Tredget, Y Marcoux, PG Scott, A Ghahary |
Journal of Investigative Dermatology | 2002 |
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Latent Transforming Growth Factor-β Activation in Mammary Gland
KB Ewan, G Shyamala, SA Ravani, Y Tang, R Akhurst, L Wakefield, MH Barcellos-Hoff |
The American Journal of Pathology | 2002 |
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The pulmonary physician in critical care * 6: The pathogenesis of ALI/ARDS
GJ Bellingan |
Thorax | 2002 |
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Focusing on diffuse (interstitial) lung disease: a rapidly evolving field
RM du Bois |
Respiratory Research | 2002 |
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Latent transforming growth factor-beta activation in mammary gland: regulation by ovarian hormones affects ductal and alveolar proliferation
KB Ewan, G Shyamala, SA Ravani, Y Tang, R Akhurst, L Wakefield, MH Barcellos-Hoff |
The American Journal of Pathology | 2002 |
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Aerosolized adrenomedullin suppresses pulmonary transforming growth factor-β1 and interleukin-1β gene expression in vivo
K der Hardt, MA Kandler, K Popp, E Schoof, M Chada, W Rascher, J Dötsch |
European Journal of Pharmacology | 2002 |
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Gene Therapy in Lung Disease
K Amin |
Gene Therapy in Lung Disease | 2002 |
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Oxidant-mediated increases in redox factor-1 nuclear protein and activator protein-1 DNA binding in asbestos-treated macrophages
DM Flaherty, MM Monick, AB Carter, MW Peterson, GW Hunninghake |
Journal of immunology (Baltimore, Md. : 1950) | 2002 |
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Differences in the Fibrogenic Response after Transfer of Active Transforming Growth Factor- β 1 Gene to Lungs of “Fibrosis-prone” and “Fibrosis-resistant” Mouse Strains
M Kolb, P Bonniaud, T Galt, PJ Sime, MM Kelly, PJ Margetts, J Gauldie |
American journal of respiratory cell and molecular biology | 2002 |
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Soluble Transforming Growth Factor- β Type III Receptor Gene Transfection Inhibits Fibrous Airway Obliteration in a Rat Model of Bronchiolitis Obliterans
M Liu, M Suga, AL MacLEAN, JA St. George, DW Souza, S Keshavjee |
American journal of respiratory and critical care medicine | 2002 |
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Inflammatory Mechanisms Are Not a Minor Component of the Pathogenesis of Idiopathic Pulmonary Fibrosis
RM Strieter |
American journal of respiratory and critical care medicine | 2002 |
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Inflammatory Mechanisms Are a Minor Component of the Pathogenesis of Idiopathic Pulmonary Fibrosis
J Gauldie |
American journal of respiratory and critical care medicine | 2002 |
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Susceptibility to Asbestos-Induced and Transforming Growth Factor- β 1 –Induced Fibroproliferative Lung Disease in Two Strains of Mice
GS Warshamana, DA Pociask, P Sime, DA Schwartz, AR Brody |
American journal of respiratory cell and molecular biology | 2002 |
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A Matrix for New Ideas in Pulmonary Fibrosis
DN Cook, DM Brass, DA Schwartz |
American journal of respiratory cell and molecular biology | 2002 |
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Roles for Insulin-Like Growth Factor I and Transforming Growth Factor-β in Fibrotic Lung Disease*
PM Krein, BW Winston |
Chest | 2002 |
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p38 MAPK activation by TGF-β1 increases MLC phosphorylation and endothelial monolayer permeability
PL Goldberg, DE MacNaughton, RT Clements, FL Minnear, PA Vincent |
American journal of physiology. Lung cellular and molecular physiology | 2002 |
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Metalloproteinase and growth factor interactions: do they play a role in pulmonary fibrosis?
MK Winkler, JL Fowlkes |
American journal of physiology. Lung cellular and molecular physiology | 2002 |
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TGF-β effects on epithelial ion transport and barrier: reduced Cl − secretion blocked by a p38 MAPK inhibitor
K Howe, J Gauldie, DM McKay |
American journal of physiology. Cell physiology | 2002 |
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Gene Transfection and Expression of Transforming Growth Factor-β1 in Nonobese Diabetic Mouse Islets Protects β-Cells in Syngeneic Islet Grafts from Autoimmune Destruction
WL Suarez-Pinzon, Y Marcoux, A Ghahary, A Rabinovitch |
Cell Transplantation | 2002 |
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Drug Discovery and Evaluation
HG Vogel, WH Vogel, BA Schölkens, J Sandow, G Müller, WF Vogel |
2002 | |
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Growth factors in development, repair and disease
S Braun, U auf dem Keller, HD Beer, M Krampert, M Müller, S Werner, C Dickson, S Werner |
European Journal of Cell Biology | 2002 |
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Transient gene transfer of IL-1beta to the lung induces acute tissue injury and chronic repair leading to pulmonary fibrosis
Martin Kolb, Peter J. Margetts, Daniel C. Anthony, Fernando Pitossi, Jack Gauldie |
Journal of Clinical Investigation | 2001 |
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Pulmonary fibrosis: A cellular over-reaction or a failure of communication?
Dean Sheppard |
Journal of Clinical Investigation | 2001 |
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Cyclooxygenase-2 deficiency results in a loss of the anti-proliferative response to transforming growth factor-beta in human fibrotic lung fibroblasts and promotes bleomycin-induced pulmonary fibrosis in mice
CB Keerthisingam, RG Jenkins, NK Harrison, NA Hernandez-Rodriguez, H Booth, GJ Laurent, SL Hart, ML Foster, RJ McAnulty |
The American Journal of Pathology | 2001 |
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A new direction in the pathogenesis of idiopathic pulmonary fibrosis?
J Gauldie, M Kolb, PJ Sime |
Respiratory Research | 2001 |
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The many faces of transforming growth factor-β in pleural diseases
YC Lee, KB Lane |
Current Opinion in Pulmonary Medicine | 2001 |
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The bronchial epithelium in chronic and severe asthma
DE Davies |
Current Allergy and Asthma Reports | 2001 |
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Fibrosis of the Lung and Other Tissues: New Concepts in Pathogenesis and Treatment
PJ Sime, KM O'Reilly |
Clinical Immunology | 2001 |
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The bronchial epithelium: translating gene and environment interactions in asthma
DE Davies |
Current Opinion in Allergy and Clinical Immunology | 2001 |
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Recipient intramuscular gene transfer of active transforming growth factor-β1 attenuates acute lung rejection
T Suda, F D’Ovidio, N Daddi, JH Ritter, T Mohanakumar, GA Patterson |
The Annals of Thoracic Surgery | 2001 |
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Role of gob-5 in mucus overproduction and airway hyperresponsiveness in asthma
A Nakanishi, S Morita, H Iwashita, Y Sagiya, Y Ashida, H Shirafuji, Y Fujisawa, O Nishimura, M Fujino |
Proceedings of the National Academy of Sciences | 2001 |
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Localisation of transforming growth factor beta1 and beta3 mRNA transcripts in normal and fibrotic human lung
RK Coker, GJ Laurent, PK Jeffery, RM du Bois, CM Black, RJ McAnulty |
Thorax | 2001 |
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Recombinant soluble betaglycan is a potent and isoform-selective transforming growth factor-beta neutralizing agent
MM Vilchis-Landeros, JL Montiel, V Mendoza, G Mendoza-Hernández, F López-Casillas |
Biochemical Journal | 2001 |
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Non-penetrating Vascular Clips Anastomosis Inhibited Intimal Thickening Under Poor Runoff Conditions in Canine Autogenous Vein Grafts
K Komori, T Shoji, T Furuyama, Y Yonemitsu, E Mori, T Yamaoka, T Matsumoto, K Sugimachi |
European Journal of Vascular and Endovascular Surgery | 2001 |
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GM-CSF Increases AP-1 DNA Binding and Ref-1 Amounts in Human Alveolar Macrophages
DM Flaherty, MM Monick, AB Carter, MW Peterson, GW Hunninghake |
American journal of respiratory cell and molecular biology | 2001 |
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Do lung remodeling, repair, and regeneration recapitulate respiratory ontogeny?
D Warburton, D Tefft, A Mailleux, S Bellusci, JP Thiery, J Zhao, S Buckley, W Shi, B Driscoll |
American journal of respiratory and critical care medicine | 2001 |
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Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation
AC Bakker, FA de Loo, HM Beuningen, P Sime, PL Lent, PM der Kraan, CD Richards, WB Berg |
Osteoarthritis and Cartilage | 2001 |
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Transient Transgene Expression of Decorin in the Lung Reduces the Fibrotic Response to Bleomycin
M Kolb, PJ Margetts, T Galt, PJ Sime, Z Xing, M Schmidt, J Gauldie |
American journal of respiratory and critical care medicine | 2001 |
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AP Endonucleases and the Many Functions of Ref-1
DM Flaherty, MM Monick, GW Hunninghake |
American journal of respiratory cell and molecular biology | 2001 |
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Transforming Growth Factor- β 1 Overexpression in Tumor Necrosis Factor- α Receptor Knockout Mice Induces Fibroproliferative Lung Disease
JY Liu, PJ Sime, T Wu, GS Warshamana, D Pociask, SY Tsai, AR Brody |
American journal of respiratory cell and molecular biology | 2001 |
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Bronchopulmonary Dysplasia
AH Jobe, E Bancalari |
American journal of respiratory and critical care medicine | 2001 |
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Activation of Fibroblast Procollagen α1(I) Transcription by Mechanical Strain Is Transforming Growth Factor-β-dependent and Involves Increased Binding of CCAAT-binding Factor (CBF/NF-Y) at the Proximal Promoter
GE Lindahl, RC Chambers, J Papakrivopoulou, SJ Dawson, MC Jacobsen, JE Bishop, GJ Laurent |
The Journal of biological chemistry | 2001 |
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Dominant-negative TAK1 induces c-Myc and G 0 exit in liver
CA Bradham, E Hatano, DA Brenner |
AJP Gastrointestinal and Liver Physiology | 2001 |
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Autocrine expression of activated transforming growth factor-β 1 induces apoptosis in normal rat liver
LW Schrum, MA Bird, O Salcher, ER Burchardt, JW Grisham, DA Brenner, RA Rippe, KE Behrns |
AJP Gastrointestinal and Liver Physiology | 2001 |
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Molecular mechanisms of TGF-β antagonism by interferon γ and cyclosporine A in lung fibroblasts
OL Eickelberg, A Pansky, E Koehler, M Bihl, M Tamm, P Hildebrand, AP Perruchoud, M Kashgarian, M Roth |
The FASEB Journal | 2001 |
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Proteoglycans decorin and biglycan differentially modulate TGF-β-mediated fibrotic responses in the lung
M Kolb, PJ Margetts, PJ Sime, J Gauldie |
American journal of physiology. Lung cellular and molecular physiology | 2001 |
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Antifibrotic Therapy for Idiopathic Pulmonary Fibrosis:
PS Acharya, DA Zisman |
Clinical Pulmonary Medicine | 2001 |
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Plusieurs voies pour la fibrose interstitielle pulmonaire ?
AR Brody |
médecine/sciences | 2001 |
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Peripheral Blood Fibrocytes: Differentiation Pathway and Migration to Wound Sites
R Abe, SC Donnelly, T Peng, R Bucala, CN Metz |
Journal of immunology (Baltimore, Md. : 1950) | 2001 |
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Gene Transfer of Transforming Growth Factor-β1 to the Rat Peritoneum: Effects on Membrane Function
PJ Margetts, M Kolb, T Galt, CM Hoff, TR Shockley, J Gauldie |
Journal of the American Society of Nephrology : JASN | 2001 |
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Localisation of transforming growth factor β 1 and β 3 mRNA transcripts in normal and fibrotic human lung
RK Coker, GJ Laurent, PK Jeffery, RM du Bois, CM Black, RJ McAnulty |
Thorax | 2001 |
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Lung fibrosis
C Fonseca, D Abraham, CM Black |
Springer Seminars in Immunopathology | 2000 |
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Progress in systemic sclerosis: Novel therapeutic paradigms
J Varga |
Current Rheumatology Reports | 2000 |
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LU135252, an endothelinAreceptor antagonist did not prevent pulmonary vascular remodelling or lung fibrosis in a rat model of myocardial infarction
QT Nguyen, F Colombo, JL Rouleau, J Dupuis, A Calderone |
British Journal of Pharmacology | 2000 |
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Fibrosis and airway remodelling
Redington |
Clinical & Experimental Allergy | 2000 |
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Interstitial fibrosis and growth factors
JA Lasky, AR Brody |
Environmental Health Perspectives | 2000 |
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Induction of Cardiac Fibrosis by Transforming Growth Factor-β1
PJ Lijnen, VV Petrov, RH Fagard |
Molecular Genetics and Metabolism | 2000 |
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Smad7 is a TGF-β-inducible attenuator of Smad2/3-mediated inhibition of embryonic lung morphogenesis
J Zhao, DL Crowe, C Castillo, C Wuenschell, Y Chai, D Warburton |
Mechanisms of Development | 2000 |
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Dose-dependent induction of transforming growth factor β (TGF-β) in the lung tissue of fibrosis-prone mice after thoracic irradiation
CE Rübe, D Uthe, KW Schmid, KD Richter, J Wessel, A Schuck, N Willich, C Rübe |
International journal of radiation oncology, biology, physics | 2000 |
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Increased expression of connective tissue growth factor in fibrotic human liver and in activated hepatic stellate cells
EJ Williams, MD Gaça, DR Brigstock, MJ Arthur, RC Benyon |
Journal of Hepatology | 2000 |
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A Single Intrapleural Injection of Transforming Growth Factor- β 2 Produces an Excellent Pleurodesis in Rabbits
RW Light, DS Cheng, YC Lee, J Rogers, J Davidson, KB Lane |
American journal of respiratory and critical care medicine | 2000 |
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Treatment of Experimental (Trinitrobenzene Sulfonic Acid) Colitis by Intranasal Administration of Transforming Growth Factor (Tgf)-β1 Plasmid: TGF-β1–Mediated Suppression of T Helper Cell Type 1 Response Occurs by Interleukin (Il)-10 Induction and IL-12 Receptor β2 Chain Downregulation
A Kitani, IJ Fuss, K Nakamura, OM Schwartz, T Usui, W Strober |
Journal of Experimental Medicine | 2000 |
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Smad7 and Smad6 Differentially Modulate Transforming Growth Factor β-induced Inhibition of Embryonic Lung Morphogenesis
J Zhao, W Shi, H Chen, D Warburton |
The Journal of biological chemistry | 2000 |
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V. TGF-β signaling pathways
RG Wells |
AJP Gastrointestinal and Liver Physiology | 2000 |
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Role of Transforming Growth Factor-β1 in Cardiovascular Inflammatory Changes Induced by Chronic Inhibition of Nitric Oxide Synthesis
M Koyanagi, K Egashira, M Kubo-Inoue, M Usui, S Kitamoto, H Tomita, H Shimokawa, A Takeshita |
Hypertension | 2000 |
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Yearbook of Intensive Care and Emergency Medicine 2000
JL Vincent |
2000 | |
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Airway wall remodelling: does it occur and what does it mean?
Kips, Pauwels |
Clinical & Experimental Allergy | 1999 |
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A Mechanism for Regulating Pulmonary Inflammation and Fibrosis: The Integrin αvβ6 Binds and Activates Latent TGF β1
JS Munger, X Huang, H Kawakatsu, MJ Griffiths, SL Dalton, J Wu, JF Pittet, N Kaminski, C Garat, MA Matthay, DB Rifkin, D Sheppard |
Cell | 1999 |
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Adenovirus Vector Expressing Mouse Oncostatin M Induces Acute-Phase Proteins and TIMP-1 ExpressionIn Vivoin Mice
C Kerr, C Langdon, F Graham, J Gauldie, T Hara, CD Richards |
Journal of Interferon & Cytokine Research | 1999 |
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Reduction of bleomycin induced lung fibrosis by transforming growth factor beta soluble receptor in hamsters
Q Wang, Y Wang, DM Hyde, PJ Gotwals, VE Koteliansky, ST Ryan, SN Giri |
Thorax | 1999 |
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TGF-β and fibrosis
MH Branton, JB Kopp |
Microbes and Infection | 1999 |
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A Preliminary Study of Long-Term Treatment with Interferon Gamma-1b and Low-Dose Prednisolone in Patients with Idiopathic Pulmonary Fibrosis
R Ziesche, E Hofbauer, K Wittmann, V Petkov, LH Block |
New England Journal of Medicine | 1999 |
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Spatial-specific TGF-β1 adenoviral expression determines morphogenetic phenotypes in embryonic mouse lung
J Zhao, PJ Sime, P Bringas, JD Tefft, S Buckley, D Bu, J Gauldie, D Warburton |
European Journal of Cell Biology | 1999 |
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Intratracheal injection of adenovirus containing the human MNSOD transgene protects athymic nude mice from irradiation-induced organizing alveolitis
MW Epperly, JA Bray, S Krager, LM Berry, W Gooding, JF Engelhardt, R Zwacka, EL Travis, JS Greenberger |
International journal of radiation oncology, biology, physics | 1999 |
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The role of TGFβ1 in initiating hepatic stellate cell activation in vivo
C Hellerbrand, B Stefanovic, F Giordano, ER Burchardt, DA Brenner |
Journal of Hepatology | 1999 |
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Lung Fibrosis Induced by Silica Particles in NMRI Mice Is Associated with an Upregulation of the p40 Subunit of Interleukin-12 and Th-2 Manifestations
F Huaux, C Lardot, M Arras, M Delos, MC Many, JP Coutelier, JP Buchet, JC Renauld, D Lison |
American journal of respiratory cell and molecular biology | 1999 |
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TGF-β2 is increased after fetal tracheal occlusion
TM Quinn, KG Sylvester, Y Kitano, Y Kitano, KW Liechty, BP Jarrett, NS Adzick, AW Flake |
Journal of Pediatric Surgery | 1999 |
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Extracellular matrix deposition by primary human lung fibroblasts in response to TGF-β1 and TGF-β3
O Eickelberg, E Köhler, F Reichenberger, S Bertschin, T Woodtli, P Erne, AP Perruchoud, M Roth |
American journal of physiology. Lung cellular and molecular physiology | 1999 |
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Bacterial cell wall polymers promote intestinal fibrosis by direct stimulation of myofibroblasts
EA van Tol, L Holt, FL Li, FM Kong, R Rippe, M Yamauchi, J Pucilowska, PK Lund, RB Sartor |
AJP Gastrointestinal and Liver Physiology | 1999 |
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Molecular embryology of the lung: then, now, and in the future
D Warburton, J Zhao, MA Berberich, M Bernfield |
American journal of physiology. Lung cellular and molecular physiology | 1999 |
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Tissue Repair and Fibrosis
A Desmoulière, B Tuchweber |
1999 | |
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Transfer of Tumor Necrosis Factor-α to Rat Lung Induces Severe Pulmonary Inflammation and Patchy Interstitial Fibrogenesis with Induction of Transforming Growth Factor-β1 and Myofibroblasts
PJ Sime, RA Marr, D Gauldie, Z Xing, BR Hewlett, FL Graham, J Gauldie |
The American Journal of Pathology | 1998 |
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Transfer of tumor necrosis factor-alpha to rat lung induces severe pulmonary inflammation and patchy interstitial fibrogenesis with induction of transforming growth factor-beta1 and myofibroblasts
PJ Sime, RA Marr, D Gauldie, Z Xing, BR Hewlett, FL Graham, J Gauldie |
The American Journal of Pathology | 1998 |
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Epithelium-specific adenoviral transfer of a dominant-negative mutant TGF-β type II receptor stimulates embryonic lung branching morphogenesis in culture and potentiates EGF and PDGF-AA
J Zhao, PJ Sime, P Bringas, J Gauldie, D Warburton |
Mechanisms of Development | 1998 |
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Effects of Fish Oil and α-Tocopherol in Immunoglobulin A Nephropathy in the Rat
NB Kuemmerle, W Chan, RJ Krieg, EP Norkus, H Trachtman, JC Chan |
Pediatric Research | 1998 |
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Blockade of CD40-CD40 ligand interactions protects against radiation-induced pulmonary inflammation and fibrosis
A Adawi, Y Zhang, R Baggs, P Rubin, J Williams, J Finkelstein, RP Phipps |
Clinical Immunology and Immunopathology | 1998 |
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Upregulated expression of fibroblast growth factor (FGF) receptors by transforming growth factor-beta1 (TGF-beta1) mediates enhanced mitogenic responses to FGFs in cultured human lung fibroblasts
VJ Thannickal, KD Aldweib, T Rajan, BL Fanburg |
Biochemical and Biophysical Research Communications | 1998 |
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Phenotype, function, and in vivo migration and survival of allogeneic dendritic cell progenitors genetically engineered to express TGF-beta
WC Lee, C Zhong, S Qian, Y Wan, J Gauldie, Z Mi, PD Robbins, AW Thomson, L Lu |
Transplantation | 1998 |
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Early induction of transforming growth factor-beta via angiotensin II type 1 receptors contributes to cardiac fibrosis induced by long-term blockade of nitric oxide synthesis in rats
H Tomita, K Egashira, Y Ohara, M Takemoto, M Koyanagi, M Katoh, H Yamamoto, K Tamaki, H Shimokawa, A Takeshita |
Hypertension | 1998 |
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Oxidative Stress
A Stern |
Oxidative Stress | 1985 |
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