Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • Vascular Malformations (Apr 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact

Citations to this article

Human histocompatibility leukocyte antigen-binding supermotifs predict broadly cross-reactive cytotoxic T lymphocyte responses in patients with acute hepatitis.
R Bertoni, … , F V Chisari, A Sette
R Bertoni, … , F V Chisari, A Sette
Published August 1, 1997
Citation Information: J Clin Invest. 1997;100(3):503-513. https://doi.org/10.1172/JCI119559.
View: Text | PDF
Research Article Article has an altmetric score of 6

Human histocompatibility leukocyte antigen-binding supermotifs predict broadly cross-reactive cytotoxic T lymphocyte responses in patients with acute hepatitis.

  • Text
  • PDF
Abstract

Research Article

Authors

R Bertoni, J Sidney, P Fowler, R W Chesnut, F V Chisari, A Sette

×

Total citations by year

Year: 2024 2022 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1995 1988 Total
Citations: 2 3 1 7 2 1 1 4 3 2 6 4 2 4 11 11 9 7 5 9 6 9 12 7 6 1 1 1 137
Citation information
This citation data is accumulated from CrossRef, which receives citation information from participating publishers, including this journal. Not all publishers participate in CrossRef, so this information is not comprehensive. Additionally, data may not reflect the most current citations to this article, and the data may differ from citation information available from other sources (for example, Google Scholar, Web of Science, and Scopus).

Citations to this article (137)

Title and authors Publication Year
IFN-γ decreases PD-1 in T lymphocytes from convalescent COVID-19 patients via the AKT/GSK3β signaling pathway.
Song M, Liu X, Shen W, Wang Z, Wu J, Jiang J, Liu Y, Xu T, Bian T, Zhang M, Sun W, Huang M, Ji N
Scientific Reports 2024
TCR-like bispecific antibodies toward eliminating infected hepatocytes in HBV mouse models
Shi Y, Wang Z, Xu J, Niu W, Wu Y, Guo H, Shi J, Li Z, Fu B, Hong Y, Wang Z, Guo W, Chen D, Li X, Li Q, Wang S, Gao J, Sun A, Xiao Y, Cao J, Fu L, Wu Y, Zhang T, Xia N, Yuan Q
Emerging Microbes & Infections 2024
A Systematic Review of T Cell Epitopes Defined from the Proteome of Hepatitis B Virus
Y Wu, Y Ding, C Shen
Human vaccines 2022
Screening and Identification of HBV Epitopes Restricted by Multiple Prevalent HLA-A Allotypes
Ding Y, Zhou Z, Li X, Zhao C, Jin X, Liu X, Wu Y, Mei X, Li J, Qiu J, Shen C
Frontiers in immunology 2022
Immune escape pathways from the HBV core18-27 CD8 T cell response are driven by individual HLA class I alleles
Walker A, Schwarz T, Brinkmann-Paulukat J, Wisskirchen K, Menne C, Alizei ES, Kefalakes H, Theissen M, Hoffmann D, Schulze zur Wiesch J, Maini MK, Cornberg M, Kraft AR, Keitel V, Bock HH, Horn PA, Thimme R, Wedemeyer H, Heinemann FM, Luedde T, Neumann-Haefelin C, Protzer U, Timm J
Frontiers in immunology 2022
Checkpoint Inhibitors and Therapeutic Vaccines for the Treatment of Chronic HBV Infection
RC Hoogeveen, A Boonstra
Frontiers in immunology 2020
Phenotypic and functional differences of HBV core-specific versus HBV polymerase-specific CD8+ T cells in chronically HBV-infected patients with low viral load
A Schuch, ES Alizei, K Heim, D Wieland, MM Kiraithe, J Kemming, S Llewellyn-Lacey, Ö Sogukpinar, Y Ni, S Urban, P Zimmermann, M Nassal, F Emmerich, DA Price, B Bengsch, H Luxenburger, C Neumann-Haefelin, M Hofmann, R Thimme
Gut 2019
Multifactorial heterogeneity of virus-specific T cells and association with the progression of human chronic hepatitis B infection
Y Cheng, YO Zhu, E Becht, P Aw, J Chen, M Poidinger, PF de Sessions, ML Hibberd, A Bertoletti, SG Lim, EW Newell
Science Immunology 2019
Increased Levels of miR-155 are Related to Higher T-Cell Activation in the Peripheral Blood of Patients with Chronic Hepatitis B
J Fang, L Zhuge, H Rao, S Huang, L Jin, J Li
Genetic Testing and Molecular Biomarkers 2019
Hepatitis D Virus-Specific CD8+ T Cells Have a Memory-Like Phenotype Associated With Viral Immune Escape in Patients With Chronic Hepatitis D Virus Infection
H Kefalakes, C Koh, J Sidne, G Amanakis, A Sette, T Heller, B Rehermann
Gastroenterology 2019
Viral Hepatitis in Children: Prevention and Management
MH Chang, KB Schwarz
2019
Redundancy and Complementarity between ERAP1 and ERAP2 Revealed by their Effects on the Behcet's Disease-associated HLA-B*51 Peptidome*[S]
P Guasp, E Lorente, A Martín-Esteban, E Barnea, P Romania, D Fruci, JJ Kuiper, A Admon, JA de Castro
Molecular & cellular proteomics : MCP 2019
Hepatitis D Virus-Specific CD8+ T Cells Have a Memory-Like Phenotype Associated With Viral Immune Escape in Patients With Chronic Hepatitis D Virus Infection
H Kefalakes, C Koh, J Sidney, G Amanakis, A Sette, T Heller, B Rehermann
Gastroenterology 2019
CD8 + T-Cell Response-Associated Evolution of Hepatitis B Virus Core Protein and Disease Progress
Y Zhang, Y Wu, M Deng, D Xu, X Li, Z Xu, J Hu, H Zhang, K Liu, Y Zhao, F Gao, S Bi, GF Gao, J Zhao, WJ Liu, S Meng, JH Ou
Journal of virology 2018
Deep sequencing identifies hepatitis B virus core protein signatures in chronic hepatitis B patients
MH van der Ree, L Jansen, MR Welkers, HW Reesink, KA Feenstra, NA Kootstra
Antiviral Research 2018
Isolation and functional characterization of hepatitis B virus-specific T-cell receptors as new tools for experimental and clinical use
K Wisskirchen, K Metzger, S Schreiber, T Asen, L Weigand, C Dargel, K Witter, E Kieback, MF Sprinzl, W Uckert, M Schiemann, DH Busch, AM Krackhardt, U Protzer, N Labrecque
PloS one 2017
Adaptive immunity in HBV infection
A Bertoletti, C Ferrari
Journal of Hepatology 2016
Adaptation of the hepatitis B virus core protein to CD8 + T-cell selection pressure: VIRAL HEPATITIS
H Kefalakes, B Budeus, A Walker, C Jochum, G Hilgard, A Heinold, FM Heinemann, G Gerken, D Hoffmann, J Timm
Hepatology 2015
Natural history of chronic hepatitis B virus infection from infancy to adult life -the mechanism of inflammation triggering and long-term impacts
JF Wu, MH Chang
Journal of Biomedical Science 2015
Immunogenicity of twenty peptides representing epitopes of the hepatitis B core and surface antigens by IFN-γ response in chronic and resolved HBV
NS Brinck-Jensen, T Vorup-Jensen, PD Leutscher, C Erikstrup, E Petersen
BMC Immunology 2015
Characterization of Plasmodium falciparum Proteome at Asexual Blood Stages for Screening of Effective Vaccine Candidates: An Immunoinformatics Approach
SP Singh, V Verma, BN Mishra
Immunology and Immunogenetics Insights 2015
The Immunodominant Influenza A Virus M158-66 Cytotoxic T Lymphocyte Epitope Exhibits Degenerate Class I Major Histocompatibility Complex Restriction in Humans
JA Choo, J Liu, X Toh, GM Grotenbreg, EC Ren
Journal of virology 2014
A new unconventional HLA-A2-restricted epitope from HBV core protein elicits antiviral cytotoxic T lymphocytes
L Sun, Y Zhang, B Zhao, M Deng, J Liu, X Li, J Hou, M Gui, S Zhang, X Li, GF Gao, S Meng
Protein & Cell 2014
CD8+ T cell responses specific for hepatitis B virus core protein in patients with chronic hepatitis B virus infection
W Cao, Z Qiu, T Zhu, Y Li, Y Han, T Li
Journal of Clinical Virology 2014
Mhc supertypes confer both qualitative and quantitative resistance to avian malaria infections in a wild bird population
I Sepil, S Lachish, AE Hinks, BC Sheldon
Proceedings of the Royal Society B: Biological Sciences 2013
An immunodominant HLA-A*1101-restricted CD8+ T-cell response targeting hepatitis B surface antigen in chronic hepatitis B patients
X Chen, W Wang, S Wang, G Meng, M Zhang, B Ni, Y Wu, L Wang
Journal of General Virology 2013
Widespread Impact of HLA Restriction on Immune Control and Escape Pathways of HIV-1
JM Carlson, J Listgarten, N Pfeifer, V Tan, C Kadie, BD Walker, T Ndung'u, R Shapiro, J Frater, ZL Brumme, PJ Goulder, D Heckerman
Journal of virology 2012
Gastroenterology and Nutrition: Neonatology Questions and Controversies
RM Patel, AS Neish, P Lin
Gastroenterology and Nutrition: Neonatology Questions and Controversies 2012
Identification of HLA-A*0201-restricted CD8+ T-cell epitope C64–72 from hepatitis B virus core protein
Q Liu, Y Zheng, Y Yu, Q Tan, X Huang
International Immunopharmacology 2012
Suppression of Furin by Interferon-γ and the Impact on Hepatitis B Virus Antigen Biosynthesis in Human Hepatocytes
JF Wu, HY Hsu, YH Ni, HL Chen, TC Wu, MH Chang
The American Journal of Pathology 2012
A viral, transporter associated with antigen processing (TAP)-independent, high affinity ligand with alternative interactions endogenously presented by the nonclassical human leukocyte antigen E class I molecule
E Lorente, S Infantes, D Abia, E Barnea, I Beer, R García, F Lasala, M Jiménez, C Mir, A Morreale, A Admon, D López
The Journal of biological chemistry 2012
Structural and functional distinctiveness of HLA-A2 allelic variants
KY Chen, J Liu, EC Ren
Immunologic Research 2012
Parallel decline of CD8+CD38+ lymphocytes and viremia in treated hepatitis B patients
W Cao, ZF Qiu, TS Li
World journal of gastroenterology : WJG 2011
HLA class I allele promiscuity revisited
X Rao, I Hoof, AI Costa, D Baarle, C Keşmir
Immunogenetics 2011
TAP-independent human histocompatibility complex-Cw1 antigen processing of an HIV envelope protein conserved peptide
E Lorente, S Infantes, E Barnea, I Beer, R García, F Lasala, M Jiménez, A Admon, D López
AIDS 2011
Multiple Viral Ligands Naturally Presented by Different Class I Molecules in Transporter Antigen Processing-Deficient Vaccinia Virus-Infected Cells
E Lorente, S Infantes, E Barnea, I Beer, R Garcia, F Lasala, M Jimenez, C Vilches, FA Lemonnier, A Admon, D Lopez
Journal of virology 2011
HBcAg18–27 epitope fused to HIV-Tat49–57 adjuvanted with CpG ODN induces immunotherapeutic effects in transgenic mice
S Wang, Q Han, N Zhang, J Chen, Z Liu, G Zhang, Z Li
Immunology Letters 2010
Computational characterization of Plasmodium falciparum proteomic data for screening of potential vaccine candidates
SP Singh, F Khan, BN Mishra
Human Immunology 2010
Identification of naturally processed ligands in the C57BL/6 mouse using large-scale mass spectrometric peptide sequencing and bioinformatics prediction
JC Delgado, H Escobar, DK Crockett, E Reyes-Vargas, PE Jensen
Immunogenetics 2009
Silencing an immunodominant epitope of hepatitis B surface antigen reveals an alternative repertoire of CD8 T cell epitopes of this viral antigen
A Wieland, P Riedl, J Reimann, R Schirmbeck
Vaccine 2009
A novel method to estimate the affinity of HLA-A∗0201 restricted CTL epitope
Y Xu, Y Lin, B Zhu, Z Lin
Journal of Molecular Structure 2009
Elimination of Immunodominant Epitopes from Multispecific DNA-Based Vaccines Allows Induction of CD8 T Cells That Have a Striking Antiviral Potential
P Riedl, A Wieland, K Lamberth, S Buus, F Lemonnier, K Reifenberg, J Reimann, R Schirmbeck
Journal of immunology (Baltimore, Md. : 1950) 2009
Host ethnicity and virus genotype shape the hepatitis B virus-specific T-cell repertoire
AT Tan, E Loggi, C Boni, A Chia, AJ Gehring, KS Sastry, V Goh, P Fisicaro, P Andreone, C Brander, SG Lim, C Ferrari, F Bihl, A Bertoletti
Journal of virology 2008
Gender-Dependent HLA-DR-Restricted Epitopes Identified from Herpes Simplex Virus Type 1 Glycoprotein D
X Zhang, FA Castelli, X Zhu, M Wu, B Maillère, L BenMohamed
Clinical and vaccine immunology : CVI 2008
A mutant HBs antigen (HBsAg)183-191 epitope elicits specific cytotoxic T lymphocytes in acute hepatitis B patients
HG Liu, ZP Fan, WW Chen, HY Yang, QF Liu, H Zhang, P Tien, FS Wang
Clinical & Experimental Immunology 2008
Understanding the immunopathogenesis of chronic hepatitis B virus: An Asian prospective
AT Tan, S Koh, V Goh, A Bertoletti
Journal of Gastroenterology and Hepatology 2008
HLA Class I-T cell epitopes from trans-sialidase proteins reveal functionally distinct subsets of CD8+ T cells in chronic Chagas disease
MG Alvarez, M Postan, DB Weatherly, MC Albareda, J Sidney, A Sette, C Olivera, AH Armenti, RL Tarleton, SA Laucella
PLoS neglected tropical diseases 2008
HLA class I supertypes: a revised and updated classification
J Sidney, B Peters, N Frahm, C Brander, A Sette
BMC Immunology 2008
HLA Class I-T Cell Epitopes from trans-Sialidase Proteins Reveal Functionally Distinct Subsets of CD8+ T Cells in Chronic Chagas Disease
MG Alvarez, M Postan, DB Weatherly, MC Albareda, J Sidney, A Sette, C Olivera, AH Armenti, RL Tarleton, SA Laucella, E Carvalho
PLoS neglected tropical diseases 2008
An Asymmetric Model of Heterozygote Advantage at Major Histocompatibility Complex Genes: Degenerate Pathogen Recognition and Intersection Advantage
RJ Stoffels, HG Spencer
Genetics 2008
Rational Design of a Multiepitope Vaccine Encoding T-Lymphocyte Epitopes for Treatment of Chronic Hepatitis B Virus Infections
E Depla, AV der Aa, BD Livingston, C Crimi, K Allosery, VD Brabandere, J Krakover, S Murthy, M Huang, S Power, L Babé, C Dahlberg, D McKinney, A Sette, S Southwood, R Philip, MJ Newman, L Meheus
Journal of virology 2008
Large Scale Mass Spectrometric Profiling of Peptides Eluted from HLA Molecules Reveals N-Terminal-Extended Peptide Motifs
H Escobar, DK Crockett, E Reyes-Vargas, A Baena, AL Rockwood, PE Jensen, JC Delgado
Journal of immunology (Baltimore, Md. : 1950) 2008
Broadly Immunogenic HLA Class I Supertype-Restricted Elite CTL Epitopes Recognized in a Diverse Population Infected with Different HIV-1 Subtypes
CL Pérez, MV Larsen, R Gustafsson, MM Norström, A Atlas, DF Nixon, M Nielsen, O Lund, AC Karlsson
Journal of immunology (Baltimore, Md. : 1950) 2008
Impact of hepatitis B virus basic core promoter mutations on T cell response to an immunodominant HBx-derived epitope
SL Malmassari, Q Deng, H Fontaine, D Houitte, F Rimlinger, V Thiers, B Maillere, S Pol, ML Michel
Hepatology 2007
Vaccines and immunotherapies against hepatitis B and hepatitis C viruses
G Inchauspé, ML Michel
Journal of Viral Hepatitis 2007
The high prevalence of the I27 mutant HBcAg18–27 epitope in Chinese HBV-infected patients and its cross-reactivity with the V27 prototype epitope
HG Liu, W Chen, ZP Fan, H Yang, M Shi, Z Zhang, SS Luan, H Zhang, P Lu, P Tien, FS Wang
Clinical Immunology 2007
Development of an epitope conservancy analysis tool to facilitate the design of epitope-based diagnostics and vaccines
HH Bui, J Sidney, W Li, N Fusseder, A Sette
BMC bioinformatics 2007
Extensive HLA class I allele promiscuity among viral CTL epitopes
N Frahm, K Yusim, TJ Suscovich, S Adams, J Sidney, P Hraber, HS Hewitt, CH Linde, DG Kavanagh, T Woodberry, LM Henry, K Faircloth, J Listgarten, C Kadie, N Jojic, K Sango, NV Brown, E Pae, MT Zaman, F Bihl, A Khatri, M John, S Mallal, FM Marincola, BD Walker, A Sette, D Heckerman, BT Korber, C Brander
European Journal of Immunology 2007
Neutral versus adaptive genetic variation in parasite resistance: importance of major histocompatibility complex supertypes in a free-ranging primate
N Schwensow, J Fietz, KH Dausmann, S Sommer
Heredity 2007
MHC-associated mating strategies and the importance of overall genetic diversity in an obligate pair-living primate
N Schwensow, J Fietz, K Dausmann, S Sommer
Evolutionary Ecology 2007
QSAR method for prediction of protein-peptide binding affinity: Application to MHC class I molecule HLA-A*0201
C Zhao, H Zhang, F Luan, R Zhang, M Liu, Z Hu, B Fan
Journal of Molecular Graphics and Modelling 2007
HLA supertypes and immune responses to measles–mumps–rubella viral vaccine: Findings and implications for vaccine design
IG Ovsyannikova, RM Jacobson, RA Vierkant, VS Pankratz, GA Poland
Vaccine 2007
Liver Immunology
ME Gershwin, JM Vierling, MP Manns
2007
Hepatitis B Virus Splice-Generated Protein Induces T-Cell Responses in HLA-Transgenic Mice and Hepatitis B Virus-Infected Patients
M Mancini-Bourgine, F Bayard, P Soussan, Q Deng, YC Lone, D Kremsdorf, ML Michel
Journal of virology 2007
The immune response during hepatitis B virus infection
A Bertoletti, AJ Gehring
Journal of General Virology 2006
Detailed characterization of the peptide binding specificity of five common Patr class I MHC molecules
J Sidney, S Asabe, B Peters, KA Purton, J Chung, TJ Pencille, R Purcell, CM Walker, FV Chisari, A Sette
Immunogenetics 2006
Critical factors in the development of fluorescence polarization-based peptide binding assays: An equilibrium study monitoring specific peptide binding to soluble HLA-A⁎0201
R Buchli, RS VanGundy, CF Giberson, WH Hildebrand
Journal of Immunological Methods 2006
Identification and functional perspective of a novel HLA-A allele: A*0279
F Liu, S Wang, Y Ye, H Zhang, Y Zhang, W Chen
Immunogenetics 2006
The impact of HBV-DNA fluctuations on virus-specific CD8+ T cells in HBeAg+ chronic hepatitis B patients treated with a steroid and lamivudine
J Gotto, GJ Webster, D Brown, J Jenkins, GM Dusheiko, A Bertoletti
Journal of Viral Hepatitis 2006
Improving MHC binding peptide prediction by incorporating binding data of auxiliary MHC molecules
S Zhu, K Udaka, J Sidney, A Sette, KF Aoki-Kinoshita, H Mamitsuka
Bioinformatics 2006
HLA typing associated with hepatitis B E antigen seroconversion in children with chronic hepatitis B virus infection: A long-term prospective sibling cohort study in Taiwan
JF Wu, CH Chen, RP Hsieh, HH Shih, YH Chen, CR Li, CY Chiang, WY Shau, YH Ni, HL Chen, HY Hsu, MH Chang
The Journal of Pediatrics 2006
T cell receptor cross-recognition of an HIV-1 CD8+ T cell epitope presented by closely related alleles from the HLA-A3 superfamily
M Lichterfeld, KL Williams, SK Mui, SS Shah, BR Mothe, A Sette, A Kim, MN Johnston, N Burgett, N Frahm, D Cohen, C Brander, ES Rosenberg, BD Walker, M Altfeld, XG Yu
International Immunology 2006
Differential Selection Pressure Exerted on HIV by CTL Targeting Identical Epitopes but Restricted by Distinct HLA Alleles from the Same HLA Supertype
A Leslie, DA Price, P Mkhize, K Bishop, A Rathod, C Day, H Crawford, I Honeyborne, TE Asher, G Luzzi, A Edwards, CM Rosseau, JI Mullins, G Tudor-Williams, V Novelli, C Brander, DC Douek, P Kiepiela, BD Walker, PJ Goulder
Journal of immunology (Baltimore, Md. : 1950) 2006
Immune system and hepatitis B virus infection
CK Hui, GK Lau
Journal of Clinical Virology 2005
High frequency of functional anti-YMDD and -mutant cytotoxic T lymphocytes after in vitro expansion correlates with successful response to lamivudine therapy for chronic hepatitis B
CL Lin, SL Tsai, TH Lee, RN Chien, SK Liao, YF Liaw
Gut 2005
Classification of A1- and A24-supertype molecules by analysis of their MHC-peptide binding repertoires
J Sidney, S Southwood, A Sette
Immunogenetics 2005
Biochemical and structural impact of natural polymorphism in the HLA-A3 superfamily
L Li, M Bouvier
Molecular Immunology 2005
Potent enhancement of cellular and humoral immune responses against recombinant hepatitis B antigens using AS02A adjuvant in healthy adults
P Vandepapelière, B Rehermann, M Koutsoukos, P Moris, N Garçon, M Wettendorff, G Leroux-Roels
Vaccine 2005
Development and Validation of a Fluorescence Polarization-Based Competitive Peptide-Binding Assay for HLA-A*0201A New Tool for Epitope Discovery
R Buchli, RS VanGundy, HD Hickman-Miller, CF Giberson, W Bardet, WH Hildebrand
Biochemistry 2005
In Silico Identification of Supertypes for Class II MHCs
IA Doytchinova, DR Flower
Journal of immunology (Baltimore, Md. : 1950) 2005
Longitudinal analysis of CD8+ T cells specific for structural and nonstructural hepatitis B virus proteins in patients with chronic hepatitis B: implications for immunotherapy
GJ Webster, S Reignat, D Brown, GS Ogg, L Jones, SL Seneviratne, R Williams, G Dusheiko, A Bertoletti
Journal of virology 2004
Toward the Quantitative Prediction of T-Cell Epitopes: QSAR Studies on Peptides Having Affinity with the Class I MHC Molecular HLA-A*0201
L Zhihua, W Yuzhang, Z Bo, N Bing, W Li
Journal of Computational Biology 2004
Quantitative online prediction of peptide binding to the major histocompatibility complex
CK Hattotuwagama, P Guan, IA Doytchinova, C Zygouri, DR Flower
Journal of Molecular Graphics and Modelling 2004
Use of selected reaction monitoring mass spectrometry for the detection of specific MHC class I peptide antigens on A3 supertype family members
KT Hogan, JN Sutton, KU Chu, JA Busby, J Shabanowitz, DF Hunt, CL Slingluff
Cancer Immunology, Immunotherapy 2004
Cellular Immune Responses to the Hepatitis B Virus Polymerase
E Mizukoshi, J Sidney, B Livingston, M Ghany, JH Hoofnagle, A Sette, B Rehermann
Journal of immunology (Baltimore, Md. : 1950) 2004
Activation of Th1 immunity is a common immune mechanism for the successful treatment of hepatitis B and C: Tetramer assay and therapeutic implications
SL Tsai, IS Sheen, RN Chien, CM Chu, HC Huang, YL Chuang, TH Lee, SK Liao, CL Lin, GC Kuo, YF Liaw
Journal of Biomedical Science 2003
Identification of Plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data
DL Doolan, S Southwood, DA Freilich, J Sidney, NL Graber, L Shatney, L Bebris, L Florens, C Dobano, AA Witney, E Appella, SL Hoffman, JR 3rd, DJ Carucci, A Sette
Proceedings of the National Academy of Sciences 2003
Design of multi-epitope, analogue-based cancer vaccines
JD Fikes, A Sette
Expert Opinion on Biological Therapy 2003
Functional supertype of HLA-A2 in the presentation of Flu matrix p58-66 to induce CD8+ T-cell response in a Northern Chinese population
HG Zhang, XW Pang, XY Shang, Q Xing, WF Chen
Tissue Antigens 2003
A rapid method for quantitative prediction of high affinity CTL epitopes: QSAR studies on peptides having affinity with the class I MHC molecular HLA-A*0201
Z Lin, Y Wu, Y Wei, B Ni, B Zhu, L Wang
Letters in Peptide Science 2003
Cross‐Binding Between Plasmodium falciparum CTL Epitopes and HLA Class I Molecules
Y Tang, Y Lin, Y Mao, M Dong, H Wang
Immunological Investigations 2003
Advantage of rare HLA supertype in HIV disease progression
E Trachtenberg, B Korber, C Sollars, TB Kepler, PT Hraber, E Hayes, R Funkhouser, M Fugate, J Theiler, YS Hsu, K Kunstman, S Wu, J Phair, H Erlich, S Wolinsky
Nature Medicine 2003
Simultaneous Prediction of Binding Capacity for Multiple Molecules of the HLA B44 Supertype
J Sidney, S Southwood, V Pasquetto, A Sette
Journal of immunology (Baltimore, Md. : 1950) 2003
Promiscuous CTL Recognition of Viral Epitopes on Multiple Human Leukocyte Antigens: Biological Validation of the Proposed HLA A24 Supertype
SR Burrows, RA Elkington, JJ Miles, KJ Green, S Walker, SM Haryana, DJ Moss, H Dunckley, JM Burrows, R Khanna
Journal of immunology (Baltimore, Md. : 1950) 2003
Control or persistence of hepatitis B virus: The critical role of initial host-virus interactions
GJ Webster, A Bertoletti
Immunology and Cell Biology 2002
Overexpressed differentiation antigens as targets of graft-versus-leukemia reactions
JJ Molldrem, K Komanduri, E Wieder
Current Opinion in Hematology 2002
Physicochemical explanation of peptide binding to HLA-A*0201 major histocompatibility complex: A three-dimensional quantitative structure-activity relationship study
IA Doytchinova, DR Flower
Proteins: Structure, Function, and Genetics 2002
Vaccines Against Genital Herpes: Progress and Limitations
LA Morrison
Drugs 2002
A Decaepitope Polypeptide Primes for Multiple CD8 + IFN-γ and Th Lymphocyte Responses: Evaluation of Multiepitope Polypeptides as a Mode for Vaccine Delivery
J Alexander, C Oseroff, C Dahlberg, M Qin, G Ishioka, M Beebe, J Fikes, M Newman, RW Chesnut, PA Morton, K Fok, E Appella, A Sette
Journal of immunology (Baltimore, Md. : 1950) 2002
Direct Link Between mhc Polymorphism, T Cell Avidity, and Diversity in Immune Defense
I Messaoudi, JA Patiño, R Dyall, J LeMaoult, J Nikolich-Žugich
Science 2002
Quantity and quality of virus-specific CD8 cell response: relevance to the design of a therapeutic vaccine for chronic HBV infection
G Webster, A Bertoletti
Molecular Immunology 2001
Human leucocyte antigen supertypes and immune susceptibility to HIV-1, implications for vaccine design
KS MacDonald, L Matukas, JE Embree, K Fowke, J Kimani, NJ Nagelkerke, J Oyugi, P Kiama, R Kaul, MA Luscher, S Rowland-Jones, J Ndinya-Achola, E Ngugi, JJ Bwayo, FA Plummer
Immunology Letters 2001
Majority of peptides binding HLA-A∗0201 with high affinity crossreact with other A2-supertype molecules
J Sidney, S Southwood, DL Mann, MA Fernandez-Vina, MJ Newman, A Sette
Human Immunology 2001
Identification of hepatitis B virus-specific CTL epitopes presented by HLA-A*2402, the most common HLA class I allele in East Asia
Y Sobao, K Sugi, H Tomiyama, S Saito, S Fujiyama, M Morimoto, S Hasuike, H Tsubouchi, K Tanaka, M Takiguchi
Journal of Hepatology 2001
The Development of Multi-epitope Vaccines: Epitope Identification, Vaccine Design and Clinical Evaluation
A Sette, B Livingston, D McKinney, E Appella, J Fikes, J Sidney, M Newman, R Chesnut
Biologicals 2001
Degenerate Immunogenicity of an HLA-A2-Restricted Hepatitis B Virus Nucleocapsid Cytotoxic T-Lymphocyte Epitope That Is Also Presented by HLA-B51
R Thimme, KM Chang, J Pemberton, A Sette, FV Chisari
Journal of virology 2001
Enhanced immune activity of cytotoxic T-lymphocyte epitope analogs derived from positional scanning synthetic combinatorial libraries
CL Rosa, R Krishnan, S Markel, JP Schneck, R Houghten, C Pinilla, DJ Diamond
Blood 2001
CD8 + Lymphocytes from Simian Immunodeficiency Virus-Infected Rhesus Macaques Recognize 14 Different Epitopes Bound by the Major Histocompatibility Complex Class I Molecule Mamu-A*01: Implications for Vaccine Design and Testing
TM Allen, BR Mothé, J Sidney, P Jing, JL Dzuris, ME Liebl, TU Vogel, DH O'Connor, X Wang, MC Wussow, JA Thomson, JD Altman, DI Watkins, A Sette
Journal of virology 2001
Identification of New Epitopes from Four Different Tumor-Associated Antigens: Recognition of Naturally Processed Epitopes Correlates with HLA-A∗0201-Binding Affinity
E Keogh, J Fikes, S Southwood, E Celis, R Chesnut, A Sette
Journal of immunology (Baltimore, Md. : 1950) 2001
How can the cellular immune response control hepatitis B virus replication?
Maini, Bertoletti
Journal of Viral Hepatitis 2000
Selection of hepatitis B virus variants with aminoacid substitutions inside the core antigen during interferon-? therapy
K Radecke, U Protzer, M Trippler, KH B�schenfelde, G Gerken
Journal of Medical Virology 2000
Antimicrobial activity of MHC class I-restricted CD8+ T cells in human tuberculosis
S Cho, V Mehra, S Thoma-Uszynski, S Stenger, N Serbina, RJ Mazzaccaro, JL Flynn, PF Barnes, S Southwood, E Celis, BR Bloom, RL Modlin, A Sette
Proceedings of the National Academy of Sciences 2000
Identification of dominant optimal HLA-B60- and HLA-B61-restricted cytotoxic T-lymphocyte (CTL) epitopes: rapid characterization of CTL responses by enzyme-linked immunospot assay
MA Altfeld, A Trocha, RL Eldridge, ES Rosenberg, MN Phillips, MM Addo, RP Sekaly, SA Kalams, SA Burchett, K McIntosh, BD Walker, PJ Goulder
Journal of virology 2000
Human memory CTL response specific for influenza A virus is broad and multispecific
C Gianfrani, C Oseroff, J Sidney, RW Chesnut, A Sette
Human Immunology 2000
Reverse immunogenetic and polyepitopic approaches for the induction of cell-mediated immunity against bovine viral pathogens
NR Hegde, S Srikumaran
Animal Health Research Reviews 2000
Tools of the Trade in Vaccine Design
A Sette
Science 2000
Ramifications of HLA class I polymorphism and population genetics for vaccine development
DV Dawson, M Ozgur, K Sari, M Ghanayem, DD Kostyu
Genetic Epidemiology 2000
In Vitro Priming with Adenovirus/gp100 Antigen-Transduced Dendritic Cells Reveals the Epitope Specificity of HLA-A*0201-Restricted CD8 + T Cells in Patients with Melanoma
GP Linette, S Shankara, S Longerich, S Yang, R Doll, C Nicolette, FI Preffer, BL Roberts, FG Haluska
Journal of immunology (Baltimore, Md. : 1950) 2000
HLA-DR-Promiscuous T Cell Epitopes from Plasmodiumfalciparum Pre-Erythrocytic-Stage Antigens Restricted by Multiple HLA Class II Alleles
DL Doolan, S Southwood, R Chesnut, E Appella, E Gomez, A Richards, YI Higashimoto, A Maewal, J Sidney, RA Gramzinski, C Mason, D Koech, SL Hoffman, A Sette
Journal of immunology (Baltimore, Md. : 1950) 2000
Distinct Human T Cell Repertoires Mediate Immediate and Delayed-Type Hypersensitivity to the Trichophyton Antigen, Tri r 2
JA Woodfolk, SS Sung, DC Benjamin, JK Lee, TA Platts-Mills
Journal of immunology (Baltimore, Md. : 1950) 2000
Identification of Five Different Patr Class I Molecules That Bind HLA Supertype Peptides and Definition of Their Peptide Binding Motifs
DM McKinney, AL Erickson, CM Walker, R Thimme, FV Chisari, J Sidney, A Sette
Journal of immunology (Baltimore, Md. : 1950) 2000
Natural and iatrogenic variation in hepatitis B virus
SL Ngui, R Hallet, CG Teo
Reviews in Medical Virology 1999
Hepatitis B virus in hepatocarcinogenesis
MA Feitelson
Journal of Cellular Physiology 1999
Identification of murine cytotoxic T-lymphocyte epitopes of bovine herpesvirus 1
DS Zatechka, NR Hegde, K Hariharan, S Srikumaran
Vaccine 1999
The multivalent minigene approach to vaccine development
LL An, A Sette
Expert Opinion on Investigational Drugs 1999
Differential binding of viral peptides to HLA-A2 alleles. Implications for human papillomavirus type 16 E7 peptide-based vaccination against cervical carcinoma
ME Ressing, JH de Jong, RM Brandt, JW Drijfhout, WE Benckhuijsen, GM Schreuder, R Offringa, WM Kast, CJ Melief
European Journal of Immunology 1999
Immunization with the HBV core 18–27 epitope elicits CTL responses in humans expressing different HLA-A2 supertype molecules
BD Livingston, C Crimi, J Fikes, RW Chesnut, J Sidney, A Sette
Human Immunology 1999
IMMUNOPATHOGENESIS OF HEPATITIS B VIRUS INFECTION
KM Chang, FV Chisari
Clinics in Liver Disease 1999
Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi
SL Rowland-Jones, T Dong, KR Fowke, J Kimani, P Krausa, H Newell, T Blanchard, K Ariyoshi, J Oyugi, E Ngugi, J Bwayo, KS MacDonald, AJ McMichael, FA Plummer
Journal of Clinical Investigation 1998
Recognition of a novel naturally processed, A2 restricted, HCV-NS4 epitope triggers IFN-gamma release in absence of detectable cytopathicity
J Alexander, MF Guercio, JD Fikes, RW Chesnut, FV Chisari, KM Chang, E Appella, A Sette
Human Immunology 1998
Chronic hepatitis virus infection in children
MH Chang
Journal of Gastroenterology and Hepatology 1998
HLA supertypes and supermotifs: a functional perspective on HLA polymorphism
A Sette, J Sidney
Current Opinion in Immunology 1998
The optimization of helper T lymphocyte (HTL) function in vaccine development
SA Kalams, BD Walker
Immunologic Research 1998
The optimization of helper T lymphocyte (HTL) function in vaccine development
SA Kalams, BD Walker
Immunologic Research 1998
The HLA-A0207 Peptide Binding Repertoire is Limited to a Subset of the A0201 Repertoire
J Sidney, MF Guercio, S Southwood, G Hermanson, A Maewal, E Appella, A Sette
Human Immunology 1997
Induction of tumor-reactive CTL from peripheral blood and tumor-infiltrating lymphocytes of melanoma patients by in vitro stimulation with an immunodominant peptide of the human melanoma antigen MART-1
A Schmittel, U Keilholz, C Scheibenbogen
Journal of immunology (Baltimore, Md. : 1950) 1995
Advances in Virus Research
LA Babiuk, MJ Lawman, HB Ohmann
Advances in virus research 1988

← Previous 1 2 3 4 5 6 Next →

Advertisement

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts

Referenced in 9 patents
43 readers on Mendeley
See more details