JCI - Citations to Interleukin 6 causes growth impairment in transgenic mice through a decrease in insulin-like growth factor-I. A model for stunted growth in children with chronic inflammation.

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Interleukin 6 causes growth impairment in transgenic mice through a decrease in insulin-like growth factor-I. A model for stunted growth in children with chronic inflammation.

F De Benedetti, … , G Ciliberto, E Fattori

F De Benedetti, … , G Ciliberto, E Fattori

Published February 15, 1997
Citation Information: J Clin Invest. 1997;99(4):643-650. https://doi.org/10.1172/JCI119207.

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Pädiatrische Rheumatologie N Wagner, G Dannecker		2014
Clinical definition and diagnostic criteria for sarcopenia J Udaka, N Fukuda, H Yamauchi, K Marumo	The Journal of Physical Fitness and Sports Medicine	2014
Comprehensive Physiology BJ Wilkins, M Pack	Comprehensive Physiology	2013
Comprehensive Physiology BJ Wilkins, M Pack	Comprehensive Physiology	2013
Comprehensive Physiology BJ Wilkins, M Pack	Comprehensive Physiology	2013
An experimental therapy to improve skeletal growth and prevent bone loss in a mouse model overexpressing IL-6 AD Fattore, A Cappariello, M Capulli, N Rucci, M Muraca, FD Benedetti, A Teti	Osteoporosis International	2013
Interleukin-6 myokine signaling in skeletal muscle: a double-edged sword? P Muñoz-Cánoves, C Scheele, BK Pedersen, AL Serrano	FEBS Journal	2013
Childhood Infections and Adult Height in Monozygotic Twin Pairs AE Hwang, TM Mack, AS Hamilton, WJ Gauderman, L Bernstein, MG Cockburn, J Zadnick, KA Rand, JL Hopper, W Cozen	American Journal of Epidemiology	2013
Cochrane Database of Systematic Reviews: Reviews V Thaker, AL Haagensen, B Carter, Z Fedorowicz, BW Houston, V Thaker	Cochrane Database of Systematic Reviews: Reviews	2013
Mathematical modelling to restore circulating IGF-1 concentrations in children with Crohn's disease-induced growth failure: a pharmacokinetic study A Rao, JF Standing, S Naik, MO Savage, IR Sanderson	BMJ Open	2013
The Effects of Interleukin-6 Signal Blockade on Immune System, Reproductive and Skeletal Development in Juvenile Mice: IL-6R BLOCKADE ON JUVENILE DEVELOPMENT IN VIVO T Sakurai, R Takai, H Bürgin, A Shioda, Y Sakamoto, J Amano, HP Grimm, WF Richter, Y Higuchi, S Chiba, A Kawamura, M Suzuki, L Müller	Birth Defects Research Part B: Developmental and Reproductive Toxicology	2013
The association of insulin-like growth factor-1 with severity of coronary artery disease: G Yousefzadeh, M Masoomi, A Emadzadeh, A Shahesmaeili, M Sheikhvatan	Journal of Cardiovascular Medicine	2013
Potential association of obesity with IL6 G-174C polymorphism and TTV infections D Cimponeriu, C Serafinceanu, P Apostol, M Toma, M Stavarachi, I Radu, AM Craciun, S Spandole, P Nicolae, L Rusu, OM Schiopu, DA Ion	Central European Journal of Biology	2013
Effect of electrical muscle stimulation on prevention of ICU acquired muscle weakness and facilitating weaning from mechanical ventilation HA Abu-Khaber, AM Abouelela, EM Abdelkarim	Alexandria Journal of Medicine	2013
Decreased IGF-1 levels potentiate association of inflammation with all-cause and cardiovascular mortality in prevalent hemodialysis patients I Beberashvili, I Sinuani, A Azar, H Kadoshi, G Shapiro, L Feldman, J Sandbank, Z Averbukh	Growth Hormone & IGF Research	2013
Malnutrition in children with food allergies in the UK R Meyer, CD Koker, R Dziubak, C Venter, G Dominguez-Ortega, R Cutts, N Yerlett, AK Skrapak, AT Fox, N Shah	Journal of Human Nutrition and Dietetics	2013
Protective role of 17-β-estradiol towards IL-6 leukocyte expression induced by intense training in young female athletes C Tringali, L Scala, I Silvestri, J Vitale, R Scurati, G Michielon, G Alberti, B Venerando	Journal of Sports Sciences	2013
Endocrine Therapy for Growth Retardation in Paediatric Inflammatory Bowel Disease MA Altowati, RK Russell, SF Ahmed	Pediatric Drugs	2013
Impaired Growth during Childhood in Patients with Primary Ciliary Dyskinesia T Svobodová, J Djakow, D Zemková, A Cipra, P Pohunek, J Lebl	International Journal of Endocrinology	2013
Coupling physical exercise with dietary glucose supplement for treating cognitive impairment in schizophrenia: a theoretical model and future directions: Cognitive effect of exercise and glucose YK Li, CL Hui, EH Lee, WC Chang, SK Chan, CM Leung, EY Chen	Early Intervention in Psychiatry	2013
Retrospective Analysis of Efficacy and Safety of Tocilizumab Treatment in Patients with Severe Systemic-Onset Juvenile Idiopathic Arthritis Followed for 12 Months EI Alexeeva, AA Baranov, RV Denisova, SI Valieva, TM Bzarova, KB Isaeva, TV Sleptsova, EV Mitenko, NI Taybulatov, EG Chistyakova, AN Fetisova	ISRN Immunology	2013
Comprehensive Physiology R Terjung	Comprehensive Physiology	2012
Comprehensive Physiology R Terjung	Comprehensive Physiology	2012
Comprehensive Physiology R Terjung	Comprehensive Physiology	2012
Comprehensive Physiology R Terjung	Comprehensive Physiology	2012
Efficacy, safety and tolerability of tocilizumab in patients with systemic juvenile idiopathic arthritis S Yokota, T Tanaka, T Kishimoto	Therapeutic Advances in Musculoskeletal Diseases	2012
Tocilizumab in the treatment of systemic juvenile idiopathic arthritis N Nishimoto, Murakami, Tomiita	Open Access Rheumatology : Research and Reviews	2012
IL-6 signaling blockade increases inflammation but does not affect muscle function in the mdx mouse MC Kostek, K Nagaraju, E Pistilli, A Sali, SH Lai, B Gordon, YW Chen	BMC musculoskeletal disorders	2012
Treatment of Systemic Juvenile Idiopathic Arthritis with Tocilizumab - the Role of Anti-Interleukin-6 Therapy After a Decade of Treatment A Reiff	Biologics in Therapy	2012
Sarcopenia, Dynapenia, and the Impact of Advancing Age on Human Skeletal Muscle Size and Strength; a Quantitative Review WK Mitchell, J Williams, P Atherton, M Larvin, J Lund, M Narici	Frontiers in physiology	2012
An update of the role of nutritional therapy in the management of Crohn’s disease MH Alhagamhmad, AS Day, DA Lemberg, ST Leach	Journal of Gastroenterology	2012
c-Src and IL-6 inhibit osteoblast differentiation and integrate IGFBP5 signalling B Peruzzi, A Cappariello, AD Fattore, N Rucci, FD Benedetti, A Teti	Nature Communications	2012
Inhibitory effects of IL-6 on IGF-1 activity in skeletal myoblasts could be mediated by the activation of SOCS-3 N Al-Shanti, CE Stewart	Journal of Cellular Biochemistry	2012
A phase II, multicenter, open-label study evaluating dosing and preliminary safety and efficacy of canakinumab in systemic juvenile idiopathic arthritis with active systemic features N Ruperto, P Quartier, N Wulffraat, P Woo, A Ravelli, R Mouy, B Bader-Meunier, SJ Vastert, E Noseda, D D'Ambrosio, J Lecot, A Chakraborty, A Martini, A Chioato	Arthritis & Rheumatism	2012
Amplification of the response to toll-like receptor ligands by prolonged exposure to interleukin-6 in mice: Implication for the pathogenesis of macrophage activation syndrome R Strippoli, F Carvello, R Scianaro, LD Pasquale, M Vivarelli, S Petrini, L Bracci-Laudiero, FD Benedetti	Arthritis & Rheumatism	2012
Systemic juvenile idiopathic arthritis A Martini	Autoimmunity Reviews	2012
Association between the insulin-like growth factor axis in serum and periodontitis in the Study of Health in Pomerania: an exploratory study AN Harb, B Holtfreter, N Friedrich, H Wallaschofski, M Nauck, M Albers, P Meisel, R Biffar, T Kocher	Journal of Clinical Periodontology	2012
Atividade da doença de Crohn e crescimento M Tavares, R Lima, I Soro, E Trindade, JA Dias	GE Jornal Português de Gastrenterologia	2012
Two Randomized Trials of Canakinumab in Systemic Juvenile Idiopathic Arthritis N Ruperto, HI Brunner, P Quartier, T Constantin, N Wulffraat, G Horneff, R Brik, L McCann, O Kasapcopur, L Rutkowska-Sak, R Schneider, Y Berkun, I Calvo, M Erguven, L Goffin, M Hofer, T Kallinich, SK Oliveira, Y Uziel, S Viola, K Nistala, C Wouters, R Cimaz, MA Ferrandiz, B Flato, ML Gamir, I Kone-Paut, A Grom, B Magnusson, S Ozen, F Sztajnbok, K Lheritier, K Abrams, D Kim, A Martini, DJ Lovell	New England Journal of Medicine	2012
Randomized Trial of Tocilizumab in Systemic Juvenile Idiopathic Arthritis FD Benedetti, HI Brunner, N Ruperto, A Kenwright, S Wright, I Calvo, R Cuttica, A Ravelli, R Schneider, P Woo, C Wouters, R Xavier, L Zemel, E Baildam, R Burgos-Vargas, P Dolezalova, SM Garay, R Merino, R Joos, A Grom, N Wulffraat, Z Zuber, F Zulian, D Lovell, A Martini	New England Journal of Medicine	2012
Castleman disease in a child with short stature: Castleman disease with short stature T Hanada, K Okuno, S Okada, M Fujimoto, H Kuranobu, Y Hashida, J Ueyama, J Murakami, A Hayashi, K Hanaki, S Kanzaki	Pediatrics International	2012
Evolution of Inflammatory Diseases D Okin, R Medzhitov	Current biology : CB	2012
Efficacy, safety and tolerability of tocilizumab in patients with systemic juvenile idiopathic arthritis S Yokota, T Tanaka, T Kishimoto	Therapeutic Advances in Musculoskeletal Diseases	2012
Growth Factors, Nutrient Signaling, and Cardiovascular Aging L Fontana, M Vinciguerra, VD Longo, D Sinclair, B North	Circulation research	2012
Textbook of Clinical Pediatrics AY Elzouki, HA Harfi, HM Nazer, FB Stapleton, W Oh, RJ Whitley		2012
c-Src and IL-6 inhibit osteoblast differentiation and integrate IGFBP5 signalling B Peruzzi, A Cappariello, AD Fattore, N Rucci, FD Benedetti, A Teti	Nature Communications	2012
Sex Differences in Statural Growth Impairment in Crohn’s Disease: Role of IGF-1 N Gupta, RH Lustig, MA Kohn, M McCracken, E Vittinghoff	Inflammatory Bowel Diseases	2011
Role of IL-1 beta in the development of human T(H)17 cells: lesson from NLPR3 mutated patients D Lasigliè, E Traggiai, S Federici, M Alessio, A Buoncompagni, A Accogli, S Chiesa, F Penco, A Martini, M Gattorno	PloS one	2011
Effects of Deoxynivalenol Consumption on Body Weight and Adiposity in the Diet-Induced Obese Mouse CJ Amuzie, BM Flannery, AM Ulrich, JJ Pestka	Journal of Toxicology and Environmental Health, Part A	2011
Insulin-like growth factor-I and the liver K Bonefeld, S Møller	Liver International	2011
Sodium butyrate maintains growth performance by regulating the immune response in broiler chickens WH Zhang, Y Jiang, QF Zhu, F Gao, SF Dai, J Chen, GH Zhou	British Poultry Science	2011
Summary of “Growth and Nutritional Status in Pediatric Crohnʼs Disease” With a Focus on Sex Differences in Statural Growth Impairment N Gupta	Journal of Pediatric Gastroenterology and Nutrition	2011
Differentiating size-dependent responses of juvenile pink salmon (Oncorhynchus gorbuscha) to sea lice (Lepeophtheirus salmonis) infections BJ Sutherland, SG Jantzen, DS Sanderson, BF Koop, SR Jones	Comparative Biochemistry and Physiology Part D: Genomics and Proteomics	2011
Effects of insulin-like growth factor 1 in preventing acute coronary syndromes: The PRIME study JB Ruidavets, G Luc, E Machez, AL Genoux, F Kee, D Arveiler, P Morange, JV Woodside, P Amouyel, A Evans, P Ducimetière, A Bingham, J Ferrières, B Perret	Atherosclerosis	2011
Exercise Physiology of Normal Development, Sex Differences, and Aging CA Harms, D Cooper, H Tanaka	Comprehensive Physiology	2011
IL-6/IL-6 receptor system and its role in physiological and pathological conditions M Mihara, M Hashizume, H Yoshida, M Suzuki, M Shiina	Clinical Science	2011
The role of growth hormone and insulin-like growth factor-1 in Crohnʼs disease : implications for therapeutic use of human growth hormone in pediatric patients E Vortia, M Kay, R Wyllie	Current Opinion in Pediatrics	2011
IMMUNOLOGY AND RHEUMATIC DISEASES M Gattorno, A Martini	Textbook of Pediatric Rheumatology	2011
CHRONIC ARTHRITIS IN CHILDHOOD RE Petty, JT Cassidy	Textbook of Pediatric Rheumatology	2011
PHARMACOLOGY AND DRUG THERAPY NT Ilowite, RM Laxer	Textbook of Pediatric Rheumatology	2011
SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS FD Benedetti, R Schneider	Textbook of Pediatric Rheumatology	2011
Inflammatory and growth factor response to continuous and intermittent exercise in youth with cystic fibrosis T Nguyen, J Obeid, HE Ploeger, T Takken, L Pedder, BW Timmons	Journal of Cystic Fibrosis	2011
Effects of Insulin-Like Growth Factor-I on Expression of Suppressor of Cytokine Signaling-3 in C2C12 Myotube HJ Kim, WJ Lee	Journal of Life Science	2011
Rhumatologie pédiatrique : quelles avancées ? I Koné-Paut	Revue du Rhumatisme Monographies	2011
Williams Textbook of Endocrinology DW Cooke, SA Divall, S Radovick	Williams Textbook of Endocrinology	2011
Nutritional Problems and Management in Children with Inflammatory Bowel Disease JH Park	Hanyang Medical Reviews	2011
Impact of Inflammatory Bowel Disease upon Growth in Children and Adolescents V Moeeni, AS Day	ISRN Pediatrics	2011
Insulin-Like Growth Factor I and the Pathogenesis of Delirium: A Review of Current Evidence D Adamis, D Meagher	Journal of Aging Research	2011
Magnesium and anabolic hormones in older men: Magnesium and anabolic status in older men M Maggio, GP Ceda, F Lauretani, C Cattabiani, E Avantaggiato, S Morganti, F Ablondi, S Bandinelli, LJ Dominguez, M Barbagallo, G Paolisso, RD Semba, L Ferrucci	International Journal of Andrology	2011
Role of IL-1 Beta in the Development of Human TH17 Cells: Lesson from NLPR3 Mutated Patients D Lasigliè, E Traggiai, S Federici, M Alessio, A Buoncompagni, A Accogli, S Chiesa, F Penco, A Martini, M Gattorno, JE Khoury	PloS one	2011
Handbook of Growth and Growth Monitoring in Health and Disease VR Preedy		2011
Skeletal Muscle Catabolism in TNBS-Induced Murine Colitis F Puleo, K Meirelles, M Navaratnarajah, L Fitzpatrick, ML Shumate, RN Cooney, CH Lang	Metabolism: clinical and experimental	2010
Electrical muscle stimulation prevents critical illness polyneuromyopathy: a randomized parallel intervention trial C Routsi, V Gerovasili, I Vasileiadis, E Karatzanos, T Pitsolis, E Tripodaki, V Markaki, D Zervakis, S Nanas	Critical Care	2010
Final adult height of children with inflammatory bowel disease is predicted by parental height and patient minimum height Z-score JJ Lee, JC Escher, MJ Shuman, PW Forbes, LC Delemarre, BW Harr, M Kruijer, M Moret, S Allende-Richter, RJ Grand	Inflammatory Bowel Diseases	2010
Effects of type 1 diabetes mellitus on skeletal muscle: clinical observations and physiological mechanisms MP Krause, MC Riddell, TJ Hawke	Pediatric Diabetes	2010
Insulin-Like Growth Factor I Signaling in Skeletal Muscle and the Potential for Cytokine Interactions GR Adams	Medicine & Science in Sports & Exercise	2010
Transgenic mice with astrocyte-targeted production of interleukin-6 are resistant to high-fat diet-induced increases in body weight and body fat J Hidalgo, S Florit, M Giralt, B Ferrer, C Keller, H Pilegaard	Brain Behavior and Immunity	2010
Tocilizumab: Therapy and safety management T Pham, P Claudepierre, A Constantin, M Bandt, B Fautrel, L Gossec, JE Gottenberg, P Goupille, S Guillaume, E Hachulla, C Masson, J Morel, X Puéchal, A Saraux, T Schaeverbeke, D Wendling, E Bruckert, S Pol, X Mariette, J Sibilia	Joint Bone Spine	2010
Role for interleukin-6 in structural joint damage and systemic bone loss in rheumatoid arthritis BL Goff, F Blanchard, JM Berthelot, D Heymann, Y Maugars	Joint Bone Spine	2010
Rôle de l’interleukine-6 dans les destructions ostéoarticulaires et la perte osseuse systémique au cours de la polyarthrite rhumatoïde BL Goff, F Blanchard, JM Berthelot, D Heymann, Y Maugars	Revue du Rhumatisme	2010
Assessment of Growth Disturbance in Japanese Children with IBD T Shono, M Kato, Y Aoyagi, H Haruna, T Fujii, T Kudo, Y Ohtsuka, T Shimizu	International journal of pediatrics	2010
Aging and its effects on inflammation in skeletal muscle at rest and following exercise-induced muscle injury J Peake, PD Gatta, D Cameron-Smith	American Journal of Physiology - Regulatory, Integrative and Comparative Physiology	2010
Resilience in Aging B Resnick, LP Gwyther, KA Roberto		2010
Mechanisms of growth impairment in pediatric Crohn's disease TD Walters, AM Griffiths	Nature Reviews Gastroenterology & Hepatology	2009
Altered molecular adaptation to exercise in children with type 1 diabetes: beyond hypoglycemia JS Rosa, PR Galassetti	Pediatric Diabetes	2009
Inflammatory cytokines and the GH/IGF-I axis: novel actions on bone growth C Pass, VE MacRae, SF Ahmed, C Farquharson	Cell Biochemistry and Function	2009
Suppression of insulin-like growth factor acid-labile subunit expression--a novel mechanism for deoxynivalenol-induced growth retardation CJ Amuzie, JJ Pestka	Toxicological sciences : an official journal of the Society of Toxicology	2009
Induction of suppressors of cytokine signaling by the trichothecene deoxynivalenol in the mouse CJ Amuzie, J Shinozuka, JJ Pestka	Toxicological sciences : an official journal of the Society of Toxicology	2009
Association of C-reactive protein and muscle strength in the English Longitudinal Study of Ageing M Hamer, GJ Molloy	Age (Dordrecht, Netherlands)	2009
Serum IGF-I and C-reactive protein in healthy black and white young men: the CARDIA male hormone study LA Colangelo, B Chiu, P Kopp, K Liu, SM Gapstur	Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society	2009
Age-impaired fluid homeostasis depends on the balance of IL-6/IGF-I in the rat supraoptic nuclei K Palin, ML Moreau, H Orcel, A Duvoid-Guillou, A Rabié, KW Kelley, F Moos	Neurobiology of Aging	2009
A New Perspective on Deoxynivalenol and Growth Suppression KA Voss	Toxicological Sciences	2009
IGF-1, nutrition and aging: the big picture L Fontana, EP Weiss, DT Villareal, S Klein, JO Holloszy	Aging Cell	2009
Growth and long-term lung function in cystic fibrosis: A longitudinal study of patients diagnosed by neonatal screening BM Assael, G Casazza, P Iansa, S Volpi, S Milani	Pediatric Pulmonology	2009
Growth Factors, Inflammatory Cytokines and Postnatal Bone Strength in Preterm Infants A Eliakim, D Nemet, I Ahmad, F Zaldivar, R Koppel, D Grochow, F Waffarn, DM Cooper, K Saba	Journal of Pediatric Endocrinology and Metabolism	2009
Interleukin-6 inhibits early differentiation of ATDC5 chondrogenic progenitor cells S Nakajima, T Naruto, T Miyamae, T Imagawa, M Mori, S Nishimaki, S Yokota	Cytokine	2009
Local IGF-I Prevents Sepsis-Induced Muscle Atrophy G Nystrom, A Pruznak, D Huber, RA Frost, CH Lang	Metabolism: clinical and experimental	2009
Kelley's Textbook of Rheumatology J Degroot, AM Zuurmond, PP Tak	Kelley's Textbook of Rheumatology	2009
Infection and inflammation in somatic maintenance, growth and longevity EB Kopp, R Medzhitov	Evolutionary Applications	2009
Perspectives in mammalian IGFBP-3 biology: local vs. systemic action PM Yamada, KW Lee	American journal of physiology. Cell physiology	2009
Skeletal muscle growth in young rats is inhibited by chronic exposure to IL-6 but preserved by concurrent voluntary endurance exercise PW Bodell, E Kodesh, F Haddad, FP Zaldivar, DM Cooper, GR Adams	Journal of applied physiology	2009
Enteral Nutrition as a Primary Therapy of Crohn's Disease: The Pediatric Perspective W El-Matary	Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition	2009
Cartilage Oligomeric Matrix Protein in Patients with Juvenile Idiopathic Arthritis: Relation to Growth and Disease Activity B Bjørnhart, A Juul, S Nielsen, M Zak, P Svenningsen, K Müller	The Journal of rheumatology	2009
Skeletal muscle growth in young rats is inhibited by chronic exposure to IL-6 but preserved by concurrent voluntary endurance exercise PW Bodell, E Kodesh, F Haddad, FP Zaldivar, DM Cooper, GR Adams	Journal of applied physiology	2008
Clinical Immunology DB Kuhns	Clinical Immunology	2008
A pediatric perspective on inflammation and oxidative stress in response to exercise BW Timmons, S Raha	Applied Physiology, Nutrition, and Metabolism	2008
Reciprocal association of plasma IGF-1 and interleukin-6 levels with cardiometabolic risk factors in nondiabetic subjects E Succurro, F Andreozzi, A Sciacqua, A Sciaqua, ML Hribal, F Perticone, G Sesti	Diabetes care	2008
Psychoneuroimmunology F Tausk, I Elenkov, J Moynihan	Dermatologic Therapy	2008
Over-Expression of Heat Shock Protein 70 in Mice Is Associated with Growth Retardation, Tumor Formation, and Early Death V Vanhooren, XE Liu, L Desmyter, YD Fan, L Vanwalleghem, WV Molle, S Dewaele, M Praet, R Contreras, C Libert, C Chen	Rejuvenation Research	2008
Nutrition and Crohn's disease: an update of print and Web-based guidance D Moorthy, KL Cappellano, IH Rosenberg	Nutrition Reviews	2008
Does early growth hormone therapy prevent glucocorticoid-associated growth retardation in children with JIA? LG Rider, EW Leschek	Nature Clinical Practice Rheumatology	2008
Nutritional concerns in pediatric inflammatory bowel disease patients MD Kappelman, A Bousvaros	Molecular Nutrition & Food Research	2008
Specific considerations in the treatment of pediatric inflammatory bowel disease AB Grossman, RN Baldassano	Expert Review of Gastroenterology & Hepatology	2008
The IGF system and cytokine interactions and relationships with longitudinal growth in prepubertal patients with cystic fibrosis ME Street, C Spaggiari, C Volta, MA Ziveri, I Viani, M Rossi, G Pisi, GL Grzincich, S Bernasconi	Clinical Endocrinology	2008
Cystic Fibrosis: a Review of Pulmonary and Nutritional Therapies R Amin, F Ratjen	Advances in Pediatrics	2008
Beneficial synergistic interactions of TNF-α and IL-6 in C2 skeletal myoblasts—Potential cross-talk with IGF system N Al-Shanti, A Saini, SH Faulkner, CE Stewart	Growth Factors	2008
Primer on the Rheumatic Diseases JH Klippel, JH Stone, LJ Crofford, PH White		2008
Obesity CY Chen, J Blumberg	Obesity	2007
Juvenile rheumatoid arthritis DS Kim	Korean Journal of Pediatrics	2007
rhGH Treatment in Corticosteroid-Treated Patients D Simon	Hormone Research	2007
Juvenile idiopathic arthritis A Ravelli, A Martini	The Lancet	2007
Endocrine Functions of Adipose Tissue H Waki, P Tontonoz	Annual Review of Pathology: Mechanisms of Disease	2007
Diurnal secretion of growth hormone, cortisol, and dehydroepiandrosterone in pre- and perimenopausal women with active rheumatoid arthritis: a pilot case-control study MR Blackman, R Muniyappa, M Wilson, BE Moquin, HL Baldwin, KA Wong, C Snyder, M Magalnick, S Alli, J Reynolds, SM Steinberg, R Goldbach-Mansky	Arthritis Research & Therapy	2007
Molecular mechanisms of insulin resistance and associated diseases B Mlinar, J Marc, A Janež, M Pfeifer	Clinica Chimica Acta	2007
How Proinflammatory Cytokines May Impair Growth and Cause Muscle Wasting JP Thissen	Hormone Research	2007
The role of hormones, cytokines and heat shock proteins during age-related muscle loss CE Lee, A McArdle, RD Griffiths	Clinical Nutrition	2007
Kinetic Profiles of 18 Systemic Pro- and Anti-Inflammatory Mediators During and Following Exercise in Children JS Rosa, SR Oliver, RL Flores, SC Graf, AM Pontello, M Ibardolaza, FP Zaldivar, PR Galassetti	Journal of Pediatric Endocrinology and Metabolism	2007
Linear growth improves during infliximab therapy in children with chronically active severe Crohn's disease TD Walters, AR Gilman, AM Griffiths	Inflammatory Bowel Diseases	2007
Growth retardation in pediatric Crohn's disease: Pathogenesis and interventions R Shamir, M Phillip, A Levine	Inflammatory Bowel Diseases	2007
Cytokine profiling and in�vitro studies of murine bone growth using biological fluids from children with juvenile idiopathic arthritis VE MacRae, SC Wong, W Smith, A Gracie, I McInnes, P Galea, J Gardner-Medwin, C Farquharson, SF Ahmed	Clinical Endocrinology	2007
RESPONSE LETTER TO DRS. ROCKWOOD AND MITNITSKI SK Inouye, S Studenski, ME Tinetti, GA Kuchel	Journal of the American Geriatrics Society	2007
IGF-I signalling in bone growth: Inhibitory actions of dexamethasone and IL-1β VE MacRae, SF Ahmed, T Mushtaq, C Farquharson	Growth Hormone & IGF Research	2007
Artritis idiop��ticas juveniles C Job-Deslandre	EMC - Aparato Locomotor	2007
Changes and relationships of IGFS and IGFBPS and cytokines in coeliac disease at diagnosis and on gluten-free diet ME Street, C Volta, MA Ziveri, C Zanacca, G Banchini, I Viani, M Rossi, R Virdis, S Bernasconi	Clinical Endocrinology	2007
Growth Disorders 2E E Wuhl, F Schaefer	Growth Disorders 2E	2007
Arthrites juvéniles idiopathiques C Job-Deslandre	EMC - Appareil locomoteur	2007
Interleukin-6 inhibits growth hormone-mediated gene expression in hepatocytes TA Ahmed, MD Buzzelli, CH Lang, JB Capen, ML Shumate, M Navaratnarajah, M Nagarajan, RN Cooney	AJP Gastrointestinal and Liver Physiology	2007
Sarcopenic obesity and inflammation in the InCHIANTI study MA Schrager, EJ Metter, E Simonsick, A Ble, S Bandinelli, F Lauretani, L Ferrucci	Journal of applied physiology	2007
Exercise and Immune Function in Children BW Timmons	American journal of lifestyle medicine	2007
Growth Hormone Increases Final Height in Patients with Juvenile Idiopathic Arthritis: Data from a Randomized Controlled Study S Bechtold, P Ripperger, RD Pozza, W Bonfig, R Häfner, H Michels, HP Schwarz	The Journal of clinical endocrinology and metabolism	2007
Inhibition of IL-1, IL-6, and TNF-α in immune-mediated inflammatory diseases B Möller, PM Villiger	Springer Seminars in Immunopathology	2006
Impaired skeletal development in interleukin-6-transgenic mice: a model for the impact of chronic inflammation on the growing skeletal system FD Benedetti, N Rucci, AD Fattore, B Peruzzi, R Paro, M Longo, M Vivarelli, F Muratori, S Berni, P Ballanti, S Ferrari, A Teti	Arthritis & Rheumatism	2006
Skeletal muscle weakness, reduced exercise tolerance, and COPD: is systemic inflammation the missing link? DD Sin, SF Man	Thorax	2006
Pattern of growth and adiposity from infancy to adulthood in atopic dermatitis JA Ellison, L Patel, T Kecojevic, PJ Foster, TJ David, PE Clayton	British Journal of Dermatology	2006
Familial Mediterranean Fever and Growth: Effect of Disease Severity and Colchicine Treatment A Zung, G Barash, Z Zadik, J Barash	Journal of Pediatric Endocrinology and Metabolism	2006
Impact of chronic inflammation on bone during childhood M Vivarelli, FD Benedetti	Future Rheumatology	2006
Interleukin-6 and insulin-like growth factor system relationships and differences in the human placenta and fetus from the 35th week of gestation ME Street, P Seghini, MA Ziveri, S Fieni, C Volta, TM Neri, I Viani, A Bacchi-Modena, S Bernasconi	Growth Hormone & IGF Research	2006
Mouse as a Model of Growth Retardation in Cystic Fibrosis LA Rosenberg, MD Schluchter, AF Parlow, ML Drumm	Pediatric Research	2006
Impaired Growth Plate Chondrogenesis in Children with Chronic Illnesses FD Luca	Pediatric Research	2006
The Autoimmune Diseases I Kang, J Craft	The Autoimmune Diseases	2006
The chrondoprotective actions of a natural product are associated with the activation of IGF-1 production by human chondrocytes despite the presence of IL-1β MJ Miller, S Ahmed, P Bobrowski, TM Haqqi	BMC complementary and alternative medicine	2006
Inflammatory Bowel Disease and Familial Adenomatous Polyposis GG Delaini		2006
Childhood obesity and insulin resistance in a Yucatan mini-piglet model: putative roles of IGF-1 and muscle PPARs in adipose tissue activity and development SP Sébert, G Lecannu, F Kozlowski, B Siliart, JM Bard, M Krempf, MM Champ	International Journal of Obesity	2005
Role of endocrine-immune dysregulation in osteoporosis, sarcopenia, frailty and fracture risk C Joseph, AM Kenny, P Taxel, JA Lorenzo, G Duque, GA Kuchel	Molecular Aspects of Medicine	2005
Intestinal inflammation-induced growth retardation acts through IL-6 in rats and depends on the -174 IL-6 G/C polymorphism in children A Sawczenko, O Azooz, J Paraszczuk, M Idestrom, NM Croft, MO Savage, AB Ballinger, IR Sanderson	Proceedings of the National Academy of Sciences	2005
Diagnostic and Therapeutic Advances in Growth Hormone Insensitivity A David, LA Metherell, AJ Clark, C Camacho-Hübner, MO Savage	Endocrinology & Metabolism Clinics of North America	2005
Pediatric inflammatory bowel disease: What children can teach adults L Hait, A Bousvaros, R Grand	Inflammatory Bowel Diseases	2005
The Insulin-Like Growth Factor System and Markers of Inflammation in Adult Patients with Inflammatory Bowel Disease M Eivindson, JN Nielsen, H Grønbæk, A Flyvbjerg, H Hey	Hormone Research	2005
Update on the pathogenesis and treatment of systemic onset juvenile rheumatoid arthritis A Adams, TJ Lehman	Current Opinion in Rheumatology	2005
Insulin-like growth factors (IGFs) and IGF binding proteins in active Crohn's disease treated with ω-3 or ω-6 fatty acids and corticosteroids M Eivindson, H Grønbæk, JN Nielsen, J Frystyk, A Flyvbjerg, L Jørgensen, I Vind, P Munkholm, S Jensen, I Brandslund, H Hey	Scandinavian Journal of Gastroenterology	2005
A review of activity indices and end points for clinical trials in children with Crohn's disease AM Griffiths, AR Otley, J Hyams, AR Quiros, RJ Grand, A Bousvaros, BG Feagan, GR Ferry	Inflammatory Bowel Diseases	2005
NeuroImmune Biology R Solana, G Pawelec	NeuroImmune Biology	2005
Biology of Growing Animals AW Bell, PL Greenwood, RA Ehrhardt	Biology of Growing Animals	2005
Targeting the interleukin-6 receptor: A new treatment for systemic juvenile idiopathic arthritis? F Benedetti, A Martini	Arthritis & Rheumatism	2005
Inflammation is a modulator of the insulin-like growth factor (IGF)/IGF-binding protein system inducing reduced bioactivity of IGFs in cystic fibrosis ME Street, MA Ziveri, C Spaggiari, I Viani, C Volta, GL Grzincich, R Virdis, S Bernasconi	European Journal of Endocrinology	2005
The pathophysiology of the growth plate in juvenile idiopathic arthritis VE MacRae, C Farquharson, SF Ahmed	Rheumatology (Oxford, England)	2005
Alterations in growth hormone receptor abundance regulate growth hormone signaling in murine obstructive cholestasis MA Held, W Cosme-Blanco, LM Difedele, EL Bonkowski, RK Menon, LA Denson	AJP Gastrointestinal and Liver Physiology	2005
Enteral Nutrition in the Management of Crohn's Disease AM Griffiths	JPEN. Journal of parenteral and enteral nutrition	2005
IL-6-induced skeletal muscle atrophy F Haddad, F Zaldivar, DM Cooper, GR Adams	Journal of applied physiology	2005
The Anti-Inflammatory Effects of Enteral Nutrition IR Sanderson, NM Croft	JPEN. Journal of parenteral and enteral nutrition	2005
Interventions for growth failure in childhood Crohn's disease. Newby EA, Sawczenko A, Thomas AG, Wilson D	The Cochrane Database of Systematic Reviews	2005
Cochrane Database of Systematic Reviews L Hooper, C Bartlett, GD Smith, S Ebrahim, L Hooper	Cochrane Database of Systematic Reviews	2004
Endocrine Function in Thai Children Infected with Human Immunodeficiency Virus O Panamonta, P Kosalaraksa, B Thinkhamrop, W Kirdpon, C Ingehanin, P Lumbiganon	Journal of Pediatric Endocrinology and Metabolism	2004
From hormones to immunity: the physiology of immunology KW Kelley	Brain, Behavior, and Immunity	2004
Inflammatory bowel diseases in pediatric and adolescent patients: Clinical, therapeutic, and psychosocial considerations SC Kim, GD Ferry	Gastroenterology	2004
Specificities of inflammatory bowel disease in childhood AM Griffiths	Best Practice & Research Clinical Gastroenterology	2004
Exercise, stress, and inflammation in the growing child: from the bench to the playground DM Cooper, D Nemet, P Galassetti	Current Opinion in Pediatrics	2004
Growth factors in inflammatory bowel disease. The actions and interactions of growth hormone and insulin-like growth factor-I AL Theiss, S Fruchtman, PK Lund	Inflammatory Bowel Diseases	2004
Therapeutic applications of the insulin-like growth factors MO Savage, C Camacho-Hübner, DB Dunger	Growth Hormone & IGF Research	2004
Encyclopedia of Endocrine Diseases J Borén, O Wiklund	Encyclopedia of Endocrine Diseases	2004
Anti-Inflammatory and Growth-Stimulating Effects Precede Nutritional Restitution During Enteral Feeding in Crohn Disease: K Bannerjee, C Camacho-Hübner, K Babinska, KM Dryhurst, R Edwards, MO Savage, IR Sanderson, NM Croft	Journal of Pediatric Gastroenterology and Nutrition	2004
Nutrition Support for Pediatric Patients With Inflammatory Bowel Disease: A Clinical Report of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition: RE Kleinman, RN Baldassano, A Caplan, AM Griffiths, MB Heyman, RM Issenman, AM Lake	Journal of Pediatric Gastroenterology and Nutrition	2004
Enteral Nutrition in Crohn Disease: More Than Just Calories: R Heuschkel	Journal of Pediatric Gastroenterology and Nutrition	2004
Nutrition and Bone Health MF Holick, B Dawson-Hughes		2004
Senescence of human skeletal muscle impairs the local inflammatory cytokine response to acute eccentric exercise K Hamada, E Vannier, JM Sacheck, AL Witsell, R Roubenoff	The FASEB Journal	2004
Growth impairment in IL-6-overexpressing transgenic mice is associated with induction of SOCS3 mRNA J Lieskovska, D Guo, E Derman	Growth Hormone & IGF Research	2003
Hormone replacement therapy in rheumatoid arthritis is associated with lower serum levels of soluble IL-6 receptor and higher insulin-like growth factor 1 HF D'Elia, LA Mattsson, C Ohlsson, E Nordborg, H Carlsten	Arthritis Research & Therapy	2003
Growth and growth charts in cystic fibrosis L Patel, M Dixon, TJ David	Journal of the Royal Society of Medicine	2003
The Insulin-Like Growth Factor Axis in Children With Inflammatory Bowel Disease MR Corkins, AD Gohil, JF Fitzgerald	Journal of Pediatric Gastroenterology and Nutrition	2003
High-dose azathioprine in children with inflammatory bowel disease D Fuentes, F Torrente, S Keady, K Thirrupathy, MA Thomson, JA Walker-Smith, SH Murch, RB Heuschkel	Alimentary Pharmacology & Therapeutics	2003
Arthrites juvéniles et croissance staturopondérale D Simon, P Czernichow	Revue du Rhumatisme	2003
Lipopolysaccharide and proinflammatory cytokines stimulate interleukin-6 expression in C2C12 myoblasts: role of the Jun NH 2 -terminal kinase RA Frost, GJ Nystrom, CH Lang	American Journal of Physiology - Regulatory, Integrative and Comparative Physiology	2003
Interleukin-6 inhibits hepatic growth hormone signaling via upregulation of Cis and Socs-3 LA Denson, MA Held, RK Menon, SJ Frank, AF Parlow, DL Arnold	AJP Gastrointestinal and Liver Physiology	2003
Effects of aging on mortality, hypothermia, and cytokine induction in mice with endotoxemia or sepsis H Saito, ER Sherwood, TK Varma, BM Evers	Mechanisms of Ageing and Development	2003
Inflammatory Bowel Disease: From Bench to Bedside SR Targan, F Shanahan, LC Karp		2003
IL-6-overexpression brings about growth impairment potentially through a GH receptor defect J Lieskovska, D Guo, E Derman	Growth Hormone & IGF Research	2002
Chronic inflammation and the effect of IGF-I on muscle strength and power in older persons M Barbieri, L Ferrucci, E Ragno, A Corsi, S Bandinelli, M Bonafè, F Olivieri, S Giovagnetti, C Franceschi, JM Guralnik, G Paolisso	American journal of physiology. Endocrinology and metabolism	2002
Protein turnover, lipolysis, and endogenous hormonal secretion in critically ill children PE Cogo, VP Carnielli, F Rosso, A Cesarone, G Giordano, D Faggian, M Plebani, A Barreca, F Zacchello	Critical Care Medicine	2002
Adult height in patients with early onset of Crohn's disease N Alemzadeh, LT Rekers-Mombarg, ML Mearin, JM Wit, CB Lamers, RA van Hogezand	Gut	2002
Intracerebroventricular interleukin-6 treatment decreases body fat in rats K Wallenius, V Wallenius, D Sunter, SL Dickson, JO Jansson	Biochemical and Biophysical Research Communications	2002
Exercise, Diet, and Childhood Obesity: The GH-IGF-I Connection D Nemet, DM Cooper	Journal of Pediatric Endocrinology and Metabolism	2002
Breast-feeding, a complex support system for the offspring LA Hanson, M Korotkova, LI Haversen, I Mattsby-Baltzer, M Hahn-Zoric, SA Silfverdal, B Strandvik, E Telemo	Pediatrics International	2002
Relation of cord serum levels of growth hormone, insulin-like growth factors, insulin-like growth factor binding proteins, leptin, and interleukin-6 with birth weight, birth length, and head circumference in term and preterm neonates HC Lo, LY Tsao, WY Hsu, HN Chen, WK Yu, CY Chi	Nutrition	2002
Effect of Radiation Dose on the Height of Atomic Bomb Survivors: A Longitudinal Study E Nakashima, S Fujiwara, S Funamoto	Radiation Research	2002
The Effect of Endurance-Type Exercise Training on Growth Mediators and Inflammatory Cytokines in Pre-Pubertal and Early Pubertal Males TP Scheett, D Nemet, J Stoppani, CM Maresh, R Newcomb, DM Cooper	Pediatric Research	2002
Suppressors of cytokine signaling: Relevance to gastrointestinal function and disease CJ Greenhalgh, ME Miller, DJ Hilton, PK Lund	Gastroenterology	2002
Lipopolysaccharide regulates proinflammatory cytokine expression in mouse myoblasts and skeletal muscle RA Frost, GJ Nystrom, CH Lang	American Journal of Physiology - Regulatory, Integrative and Comparative Physiology	2002
In vivo neutralization of human IL-6 (hIL-6) achieved by immunization of hIL-6-transgenic mice with a hIL-6 receptor antagonist FD Benedetti, P Pignatti, M Vivarelli, C Meazza, G Ciliberto, R Savino, A Martini	Journal of immunology (Baltimore, Md. : 1950)	2001
Muscle-derived interleukin-6: possible biological effects BK Pedersen, A Steensberg, P Schjerling	The Journal of Physiology	2001
Cytokine gene polymorphisms and susceptibility to juvenile idiopathic arthritis RP Donn, JH Barrett, A Farhan, A Stopford, L Pepper, E Shelley, N Davies, WE Ollier, W Thomson	Arthritis & Rheumatism	2001
Anti-TNF Therapies Have Eliminated the Need for Steroids in Pediatric Crohn's Disease: Con. Why Use a Drug with an Unknown Long-Term Safety Profile if More Established Therapies Will Be Effective? AM Griffiths	Inflammatory Bowel Diseases	2001
Reduced serum insulin-like growth factor-1 (IGF-1) and IGF-binding protein-3 levels in adults with inflammatory bowel disease KH Katsanos, A Tsatsoulis, D Christodoulou, A Challa, A Katsaraki, EV Tsianos	Growth Hormone & IGF Research	2001
Roles of Growth Hormone and Insulin-like Growth Factor 1 in Mouse Postnatal Growth F Lupu, JD Terwilliger, K Lee, GV Segre, A Efstratiadis	Developmental Biology	2001
Regulation of insulin-like growth factor-I and of insulin-like growth factor binding protein-1, -3 and -4 in cocultures of rat hepatocytes and Kupffer cells by interleukin-6 A Lelbach, JG Scharf, G Ramadori	Journal of Hepatology	2001
The functional genomic response of developing embryonic submandibular glands to NF-kappa B inhibition M Melnick, H Chen, YM Zhou, T Jaskoll	BMC Developmental Biology	2001
The functional genomic response of developing embryonic submandibular glands to NF-kappaB inhibition M Melnick, H Chen, YM Zhou, T Jaskoll	BMC Developmental Biology	2001
Age-associated Differences in Cardiovascular Inflammatory Gene Induction during Endotoxic Stress H Saito, J Papaconstantinou	The Journal of biological chemistry	2001
GH Therapy in Juvenile Chronic Arthritis: Results of a Two-Year Controlled Study on Growth and Bone S Bechtold, P Ripperger, D Mühlbayer, H Truckenbrodt, R Häfner, O Butenandt, HP Schwarz	The Journal of clinical endocrinology and metabolism	2001
Interleukin-6 Stimulates Hepatic Insulin-Like Growth Factor Binding Protein-4 Messenger Ribonucleic Acid and Protein**This work was supported by grants from the Fund for Scientific Medical Research (Belgium), from the Fonds Spéciaux de Recherche (Université Catholique de Louvain, UCL) and from the Danone Institute (Brussels) L Fernández-Celemín, JP Thissen	Endocrinology	2001
Ubiquitous Transgenic Expression of the IL-23 Subunit p19 Induces Multiorgan Inflammation, Runting, Infertility, and Premature Death MT Wiekowski, MW Leach, EW Evans, L Sullivan, SC Chen, G Vassileva, JF Bazan, DM Gorman, RA Kastelein, S Narula, SA Lira	Journal of immunology (Baltimore, Md. : 1950)	2001
IL-6-Like Cytokines and Cancer Cachexia: Consequences of Chronic Inflammation BE Barton	Immunologic Research	2001
Energy balance, viral burden, insulin-like growth factor-1, interleukin-6 and growth impairment in children infected with human immunodeficiency virus R Johann-Liang, L O'Neill, J Cervia, I Haller, Y Giunta, T Licholai, GJ Noel	AIDS	2000
Growth failure occurs through a decrease in insulin-like growth factor 1 which is independent of undernutrition in a rat model of colitis AB Ballinger, O Azooz, T El-Haj, S Poole, MJ Farthing	Gut	2000
Muscle contractions induce interleukin-6 mRNA production in rat skeletal muscles IH Jonsdottir, P Schjerling, K Ostrowski, S Asp, EA Richter, BK Pedersen	The Journal of Physiology	2000
Chronic inflammatory bowel disease in children: a complex problem in management JA Walker-Smith	Postgraduate medical journal	2000
Nutrition in inflammatory bowel disease SC Ling, AM Griffiths	Current Opinion in Clinical Nutrition and Metabolic Care	2000
Interleukin-6 Release by Cultured Peripheral Blood Mononuclear Cells Inversely Correlates with Height Velocity, Bone Age, Insulin-like Growth Factor-I, and Insulin-like Growth Factor Binding Protein-3 Serum Levels in Children with Perinatal HIV-1 Infection M Martino, L Galli, F Chiarelli, A Verrotti, ME Rossi, G Bindi, F Galluzzi, R Salti, A Vierucci	Clinical Immunology	2000
Does the Insulin-Like Growth Factor System Interact with Prostaglandins and Proinflammatory Cytokines During Neurodegeneration? BR Lackey, SL Gray, DM Henricks	Proceedings of the Society for Experimental Biology and Medicine	2000
The mother-offspring dyad and the immune system LÅ Hanson	Acta Paediatrica	2000
Cross-sectional and Prospective Relationships of Interleukin-6 and C-Reactive Protein With Physical Performance in Elderly Persons: MacArthur Studies of Successful Aging DR Taaffe, TB Harris, L Ferrucci, J Rowe, TE Seeman	The Journals of Gerontology Series A: Biological Sciences and Medical Sciences	2000
Chronic Obstructive Pulmonary Disease PJ Barnes	New England Journal of Medicine	2000
Inflammatory cytokines and acquiredgrowth hormone resistance S Laue, RJ Ross	Growth Hormone & IGF Research	2000
Recombinant human growth hormone treatment in pediatric burn patients and its role during the hepatic acute phase response: MG Jeschke, RE Barrow, DN Herndon	Critical Care Medicine	2000
Expression of Epidermal Growth Factor in Transgenic Mice Causes Growth Retardation SY Chan, RW Wong	The Journal of biological chemistry	2000
Receptor Subunit-specific Action of Oncostatin M in Hepatic Cells and Its Modulation by Leukemia Inhibitory Factor Y Wang, O Robledo, E Kinzie, F Blanchard, C Richards, A Miyajima, H Baumann	The Journal of biological chemistry	2000
Juvenile Idiopathic Arthritis: Will Etanercept be an Improvement over Current Therapies? FD Benedetti, A Ravelli	BioDrugs	2000
New developments in IL-6 dependent biology and therapy: where do we stand and what are the options? KJ Kallen, PR Galle, S Rose-John	Expert Opinion on Investigational Drugs	1999
Acute-Phase Proteins and Other Systemic Responses to Inflammation FH Epstein, C Gabay, I Kushner	New England Journal of Medicine	1999
IGF-I Increases Interferon-γ and IL-6 mRNA Expression and Protein Production in Neonatal Mononuclear Cells W Tu, PT Cheung, YL Lau	Pediatric Research	1999
Apports protéiques chez l'enfant au cours des états d'agression B Beaufrère, JL Bresson, A Briend, J Ghisolfi, O Goulet, J Navarro, G Putet, J Rey, C Ricour, D Rieu, D Turck, M Vidailhet	Archives de Pédiatrie	1999
Cytokines et retard statural au cours des maladies inflammatoires chroniques de l'enfant FD Benedetti, A Martini	Archives de Pédiatrie	1999
Crohn's Disease in Childhood: The Case for Enteral Nutrition DR Gaya	Scottish Medical Journal	1999
The IGF System RG Rosenfeld, CT Roberts		1999
Production of interleukin-6 by synovial fibroblasts in rheumatoid arthritis H Baumann, I Kushner	The American Journal of Pathology	1998
Interleukin 6 is required for the development of collagen-induced arthritis T Alonzi, E Fattori, D Lazzaro, P Costa, L Probert, G Kollias, FD Benedetti, V Poli, G Ciliberto	Journal of Experimental Medicine	1998
Local and systemic effects of macrophage cytokines in intestinal inflammation SH Murch	Nutrition	1998
Responsiveness of IGF-I and IGFBP-3 to therapeutic intervention in children and adolescents with Crohn's disease RM Beattie, C Camacho-Hübner, S Wacharasindhu, AM Cotterill, JA Walker-Smith, MO Savage	Clinical Endocrinology	1998
Interleukin 6 Is Required for the Development of Collagen-induced Arthritis T Alonzi, E Fattori, D Lazzaro, P Costa, L Probert, G Kollias, FD Benedetti, V Poli, G Ciliberto	Journal of Experimental Medicine	1998
8 Acquired growth hormone resistance in adults RC Jenkins, RJ Ross	Baillière's Clinical Endocrinology and Metabolism	1998
1 Protein and energy requirements in healthy and ill paediatric patients JL Bresson	Bailliere's Clinical Gastroenterology	1998
5 Nutrition in inflammatory bowel disease SH Murch, JA Walker-Smith	Bailliere's Clinical Gastroenterology	1998
6 Crohn's disease in adolescents AM Griffiths, DI Program	Bailliere's Clinical Gastroenterology	1998
Hepatic production and intestinal uptake of IGF-I: response to infection CH Lang, RA Frost, J Ejiofor, DB Lacy, OP McGuinness	AJP Gastrointestinal and Liver Physiology	1998
Time for TNF? SH Murch	Journal of Pediatric Gastroenterology &amp Nutrition	1997
Le retard de croissance des maladies inflammatoires, une indication thérapeutique potentielle pour I’IGFI? M Nicolino	Archives de Pédiatrie	1997
Insulin-like growth factor-I in liver cirrhosis MC Blomsma, RJ de Knegt, RP Dullaart, PL Jansen	Journal of Hepatology	1997
Inflammatory bowel disease JL Stanford, GA Rook, J Holton, PA Jenkins, JM Grange, JI Rotter	The Lancet	1994
Rheumatology RA Asherson, R Cervera, DP D'Cruz, GR Hughes	Postgraduate medical journal	1991

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