Go to JCI Insight
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact
  • Clinical Research and Public Health
  • Current issue
  • Past issues
  • By specialty
    • COVID-19
    • Cardiology
    • Gastroenterology
    • Immunology
    • Metabolism
    • Nephrology
    • Neuroscience
    • Oncology
    • Pulmonology
    • Vascular biology
    • All ...
  • Videos
    • Conversations with Giants in Medicine
    • Video Abstracts
  • Reviews
    • View all reviews ...
    • Complement Biology and Therapeutics (May 2025)
    • Evolving insights into MASLD and MASH pathogenesis and treatment (Apr 2025)
    • Microbiome in Health and Disease (Feb 2025)
    • Substance Use Disorders (Oct 2024)
    • Clonal Hematopoiesis (Oct 2024)
    • Sex Differences in Medicine (Sep 2024)
    • Vascular Malformations (Apr 2024)
    • View all review series ...
  • Viewpoint
  • Collections
    • In-Press Preview
    • Clinical Research and Public Health
    • Research Letters
    • Letters to the Editor
    • Editorials
    • Commentaries
    • Editor's notes
    • Reviews
    • Viewpoints
    • 100th anniversary
    • Top read articles

  • Current issue
  • Past issues
  • Specialties
  • Reviews
  • Review series
  • Conversations with Giants in Medicine
  • Video Abstracts
  • In-Press Preview
  • Clinical Research and Public Health
  • Research Letters
  • Letters to the Editor
  • Editorials
  • Commentaries
  • Editor's notes
  • Reviews
  • Viewpoints
  • 100th anniversary
  • Top read articles
  • About
  • Editors
  • Consulting Editors
  • For authors
  • Publication ethics
  • Publication alerts by email
  • Advertising
  • Job board
  • Contact

Citations to this article

The oxidant stress of hyperhomocyst(e)inemia.
J Loscalzo
J Loscalzo
Published July 1, 1996
Citation Information: J Clin Invest. 1996;98(1):5-7. https://doi.org/10.1172/JCI118776.
View: Text | PDF
Editorial

The oxidant stress of hyperhomocyst(e)inemia.

  • Text
  • PDF
Abstract

Authors

J Loscalzo

×

Total citations by year

Year: 2025 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 2000 1999 1998 1997 1985 Total
Citations: 1 2 2 4 9 10 12 12 13 8 22 16 20 12 35 25 26 39 32 31 36 42 40 34 46 30 33 18 12 1 623
Citation information
This citation data is accumulated from CrossRef, which receives citation information from participating publishers, including this journal. Not all publishers participate in CrossRef, so this information is not comprehensive. Additionally, data may not reflect the most current citations to this article, and the data may differ from citation information available from other sources (for example, Google Scholar, Web of Science, and Scopus).

Citations to this article (623)

Title and authors Publication Year
Role of hyperhomocysteinemia in atherosclerosis: from bench to bedside
Tian W, Ju J, Guan B, Wang T, Zhang J, Song L, Xu H
Annals of Medicine 2025
Integrative in-silico and in-vitro analysis of taurine and vitamin B12 in modulating PPARγ and Wnt signaling in hyperhomocysteinemia-induced osteoporosis
Adhish M, Manjubala I
Biology Direct 2024
Homocysteine Modifies the Association of Coronary Stenosis and HIV Infection in an Inner City African American Population
Leucker TM, Harb T, Gerstenblith G, Celentano DD, Ziogos E, Treisman G, Mandler RN, Khalsa J, Charurat M, Lai S, Lai H
International journal of STD & AIDS 2024
Zebrafish as a Model of Cardiac Pathology and Toxicity: Spotlight on Uremic Toxins.
Coppola A, Lombari P, Mazzella E, Capolongo G, Simeoni M, Perna AF, Ingrosso D, Borriello M
International journal of molecular sciences 2023
Stroke in Parkinson's disease: a review of epidemiological studies and potential pathophysiological mechanisms.
Elfil M, Bayoumi A, Sayed A, Aladawi M, Aboutaleb PE, Grieb L, Tolba H, Tinaz S
Acta Neurologica Belgica 2023
Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet
A Brown, I Alhallak, R Simmen, S Melnyk, M Heard-Lipsmeyer, M Montales, D Habenicht, T Van, F Simmen
Cancers 2022
The binding of autotaxin to integrins mediates hyperhomocysteinemia-potentiated platelet activation and thrombosis in mice and humans.
Han L, Miao Y, Zhao Y, Zhang X, Ma X, Du X, Kong W, Xu Q, Liu J, Dai K, Feng J, Wang X
Blood Advances 2022
Impact of constipation on progression of Alzheimer's disease: A retrospective study.
Nakase T, Tatewaki Y, Thyreau B, Mutoh T, Tomita N, Yamamoto S, Takano Y, Muranaka M, Taki Y
CNS Neuroscience & Therapeutics 2022
Resolving Geroplasticity to the Balance of Rejuvenins and Geriatrins
Tabibzadeh S
Aging and disease 2022
Protecting the aging eye with hydrogen sulfide
AK George, RP Homme, D Stanisic, SC Tyagi, M Singh
Canadian Journal of Physiology and Pharmacology 2021
A narrative review on role of folate-mediated one-carbon metabolism and its associated gene polymorphisms in posing risk to preeclampsia
S Mahmood, H Younas, A Younus, S Nathenial
Clinical and Experimental Hypertension 2021
Functional inhibition of redox regulated heme proteins: A novel mechanism towards oxidative stress induced by homocysteine
GS Sharma, R Bhattacharya, LR Singh
Redox Biology 2021
Nutritional Management and Metabolic Aspects of Hyperhomocysteinemia
MI Waly
2021
Nutrition, Food and Diet in Ageing and Longevity
SI Rattan, G Kaur
2021
Associations between prenatal exposure to cadmium and lead with neural tube defect risks are modified by single-nucleotide polymorphisms of fetal MTHFR and SOD2: a case–control study
M Liu, J Yu, Z Su, Y Sun, Y Liu, Q Xie, Z Li, L Wang, J Zhang, L Jin, A Ren
Environmental Health 2021
Elevated homocysteine levels in patients with heart failure: A systematic review and meta-analysis
N Jin, L Huang, J Hong, X Zhao, Y Chen, J Hu, X Cong, Y Xie, J Pu
Medicine 2021
Effect of methylenetetrahydrofolate reductase gene polymorphisms and oxidative stress in silent brain infarction
PA Koşar, MY Tepebaşı, N Şengeze, İ İlhan, Hİ Büyükbayram, S Kutluhan
Molecular Biology Reports 2021
Characteristics and Prognosis of Stroke in Living Donor Renal Transplant Recipients.
Mizuno T, Hoshino T, Ishizuka K, Toi S, Nishimura A, Takahashi S, Wako S, Kitagawa K
Journal of Atherosclerosis and Thrombosis 2021
Gastrodin prevents homocysteine‐induced human umbilical vein endothelial cells injury via PI3K/Akt/eNOS and Nrf2/ARE pathway
J Chen, Y Huang, X Hu, X Bian, S Nian
Journal of Cellular and Molecular Medicine 2020
Characterization of Early-Stage Alcoholic Liver Disease with Hyperhomocysteinemia and Gut Dysfunction and Associated Immune Response in Alcohol Use Disorder Patients
V Vatsalya, KS Gala, AZ Hassan, J Frimodig, M Kong, N Sinha, ML Schwandt
Biomedicines 2020
The role of teratogens in neural crest development
S Cerrizuela, GA VegaLopez, MJ Aybar
Birth Defects Research Part A Clinical and Molecular Teratology 2020
The Antioxidant Role of One-Carbon Metabolism on Stroke
K Burgess, C Bennett, H Mosnier, N Kwatra, F Bethel, NM Jadavji
Antioxidants 2020
Chronopharmacological targeting of Rev-erbα by puerarin alleviates hyperhomocysteinemia in mice
M Chen, C Zhou, H Xu, T Zhang, B Wu
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2020
Metabolic Consequences of Supplemented Methionine in a Clinical Context
GC Ligthart-Melis, MP Engelen, SY Simbo, GA Have, JJ Thaden, L Cynober, NE Deutz
The Journal of nutrition 2020
Correlation between serum homocysteine, Galectin-3 concentration and atrial structural remodeling in atrial fibrillation patients
X Sun, X Li, G Liang, J Yu
Pteridines 2020
High-resolution metabolomics study revealing l-homocysteine sulfinic acid, cysteic acid, and carnitine as novel biomarkers for high acute myocardial infarction risk
A Khan, Y Choi, JH Back, S Lee, SH Jee, YH Park
Metabolism 2020
Systemic Oxidative Stress Is Increased in Postmenopausal Women and Independently Associates with Homocysteine Levels
AR Bourgonje, AE Abdulle, AM Al-Rawas, M Al-Maqbali, M Al-Saleh, MB Enriquez, S Al-Siyabi, K Al-Hashmi, I Al-Lawati, ML Bulthuis, DJ Mulder, SJ Gordijn, H van Goor, J Saleh
International journal of molecular sciences 2020
Global metabolomics analysis of serum from humans at risk of thrombotic stroke
A Khan, MS Shin, SH Jee, YH Park
The Analyst 2020
Vitamin B12 in Relation to Oxidative Stress: A Systematic Review
E van de Lagemaat, L de Groot, E van den Heuvel
Nutrients 2019
The bacterial protein CNF1 as a new strategy against Plasmodium falciparum cytoadherence
V Messina, S Loizzo, S Travaglione, L Bertuccini, M Condello, F Superti, M Guidotti, P Alano, F Silvestrini, C Fiorentini, AG Craig
PloS one 2019
Genetic Modulation of Neurocognitive Development in Cancer Patients throughout the Lifespan: a Systematic Review
C Sleurs, A Madoe, L Lagae, S Jacobs, S Deprez, J Lemiere, A Uyttebroeck
Neuropsychology Review 2019
Cell and context-dependent sorting of neuropathy-associated protein NDRG1 – insights from canine tissues and primary Schwann cell cultures
FS Skedsmo, MA Tranulis, A Espenes, K Prydz, K Matiasek, G Gunnes, LC Hermansen, KH Jäderlund
BMC veterinary research 2019
Upregulation of NDRG1 predicts poor outcome and facilitates disease progression by influencing the EMT process in bladder cancer
A Li, , C Wang, S Yang, Y Qiao, R Qiao, J Zhang
Scientific Reports 2019
CoPhosK: A method for comprehensive kinase substrate annotation using co-phosphorylation analysis
M Ayati, D Wiredja, D Schlatzer, S Maxwell, M Li, M Koyutürk, MR Chance, P Radivojac
PLoS computational biology 2019
Medial prefrontal cortex exacerbates gastric dysfunction of rats upon restraint water‑immersion stress
Dong-Qin Zhao, Sheng-Nan Gong, Ying-Jie Ma, Jian-Ping Zhu
Molecular medicine reports 2019
ОКСИДАНТНО-АНТИОКСИДАНТНА СИСТЕМА ПРИ ХРОНІЧНОМУ ОБСТРУКТИВНОМУ ЗАХВОРЮВАННІ ЛЕГЕНЬ ПРОФЕСІЙНОЇ ЕТІОЛОГІЇ
VV Ivchuk, TA Kovalchuk
2019
Proteomic study of endothelial dysfunction in response to homocysteinylated albumin
R Banarjee, A Sharma, S Bai, A Deshmukh, M Kulkarni
2019
Dietary Intakes of Vegetable Protein, Folate, and Vitamins B-6 and B-12 Are Partially Correlated with Physical Functioning of Dutch Older Adults Using Copula Graphical Models
P Behrouzi, P Grootswagers, PL Keizer, ET Smeets, EJ Feskens, LC de Groot, FA van Eeuwijk
The Journal of nutrition 2019
The interaction of maternal diabetes with mutations that affect folate metabolism and how they affect the development of neural tube defects in mice
B LópezEscobar, BJ Wlodarczyk, J CaroVega, Y Lin, RH Finnell, P YbotGonzález
Developmental Dynamics 2019
Folic Acid Protects Rat Cerebellum Against Oxidative Damage Caused by Homocysteine: the Expression of Bcl-2, Bax, and Caspase-3 Apoptotic Genes
H Koohpeyma, I Goudarzi, ME Salmani, T Lashkarbolouki, M Shabani
Neurotoxicity Research 2019
Hydrogen Sulfide: A Therapeutic Option in Systemic Sclerosis
A Abdulle, H van Goor, D Mulder
International journal of molecular sciences 2018
Restoration of skeletal muscle homeostasis by hydrogen sulfide during hyperhomocysteinemia-mediated oxidative/ER stress condition
A Majumder, M Singh, AK George, SC Tyagi
Canadian Journal of Physiology and Pharmacology 2018
Effect of homocysteine on pregnancy: A systematic review
AN Gaiday, AB Tussupkaliyev, SK Bermagambetova, SS Zhumagulova, LK Sarsembayeva, MB Dossimbetova, ZZ Daribay
Chemico-Biological Interactions 2018
Hydrogen sulfide alleviates hyperhomocysteinemia-mediated skeletal muscle atrophy via mitigation of oxidative and endoplasmic reticulum stress injury
A Majumder, M Singh, J Behera, NT Theilen, AK George, N Tyagi, N Metreveli, SC Tyagi
American journal of physiology. Cell physiology 2018
NDRG1 regulates neutral lipid metabolism in breast cancer cells
CJ Sevinsky, F Khan, L Kokabee, A Darehshouri, KR Maddipati, DS Conklin
Breast Cancer Research 2018
Effects of exercise training on stroke risk factors, homocysteine concentration, and cognitive function according the APOE genotype in stroke patients
JH Lee, SM Hong, YA Shin
Journal of Exercise Rehabilitation 2018
Causes of hyperhomocysteinemia and its pathological significance
J Kim, H Kim, H Roh, Y Kwon
Archives of Pharmacal Research 2018
Systems Biology Approaches to Redox Metabolism in Stress and Disease States
RS Wang, WM Oldham, BA Maron, J Loscalzo
Antioxidants & Redox Signaling 2018
Remote ischemic conditioning as a cytoprotective strategy in vasculopathies during hyperhomocysteinemia: An emerging research perspective: MAJUMDER et al
A Majumder, M Singh, AK George, RP Homme, A Laha, SC Tyagi
Journal of Cellular Biochemistry 2018
Endothelial nitric oxide synthase enhancer AVE3085 reverses endothelial dysfunction induced by homocysteine in human internal mammary arteries
HT Hou, J Wang, , ZQ Wang, TN Chen, JL Zhang, Q Yang, GW He
Nitric Oxide 2018
FOLATE CYCLE: PATHOGENETIC MECHANISMS OF PREGNANCY COMPLICATIONS (REVIEW)
Т Ларина, T Larina, С Супрун, S Suprun
2018
Dietary intake of nutrients involved in folate-mediated one-carbon metabolism and risk for endometrial cancer
J Lu, B Trabert, LM Liao, RM Pfeiffer, KA Michels
International Journal of Epidemiology 2018
Helicobacter pylori and gut microbiota in multiple sclerosis versus Alzheimer's disease: 10 pitfalls of microbiome studies
AM Park, S Omura, M Fujita, F Sato, I Tsunoda
Clinical and Experimental Neuroimmunology 2017
Nutritional Pathophysiology of Obesity and its Comorbidities
S Ettinger
Nutritional Pathophysiology of Obesity and its Comorbidities 2017
Helicobacter pylori and gut microbiota in multiple sclerosis versus Alzheimer's disease: 10 pitfalls of microbiome studies
AM Park, S Omura, M Fujita, F Sato, I Tsunoda
Clinical and Experimental Neuroimmunology 2017
The metabolism and significance of homocysteine in nutrition and health
A Kumar, HA Palfrey, R Pathak, PJ Kadowitz, TW Gettys, SN Murthy
Nutrition & Metabolism 2017
A metabolomic study on high-risk stroke patients determines low levels of serum lysine metabolites: a retrospective cohort study
Y Lee, A Khan, S Hong, SH Jee, YH Park
Molecular BioSystems 2017
Sodium Arsenite-Induced Learning and Memory Impairment Is Associated with Endoplasmic Reticulum Stress-Mediated Apoptosis in Rat Hippocampus
H Sun, Y Yang, H Shao, W Sun, M Gu, H Wang, L Jiang, L Qu, D Sun, Y Gao
Frontiers in molecular neuroscience 2017
Associations of C677T polymorphism in methylenetetrahydrofolate reductase (MTHFR) gene with male infertility risk: A meta-analysis
H Hong, Y Hu, X Yu, L Zhou, M Lv, Y Sun, W Ren, D Zhou
European journal of obstetrics, gynecology, and reproductive biology 2017
Effects of atorvastatin and simvastatin on oxidative stress in diet-induced hyperhomocysteinemia in Wistar albino rats: a comparative study
T Nikolic, V Zivkovic, I Srejovic, I Stojic, N Jeremic, J Jeremic, K Radonjic, S Stankovic, R Obrenovic, D Djuric, V Jakovljevic
Molecular and Cellular Biochemistry 2017
Genetic Determinants and Biochemical Correlates of Slow Coronary Flow: A Systematic Review and Meta-analysis
H Rai, N Sinha
2017
The Evaluation of Folic Acid-Deficient or Folic Acid-Supplemented Diet in the Gestational Phase of Female Rats and in Their Adult Offspring Subjected to an Animal Model of Schizophrenia
L Canever, CS Alves, G Mastella, L Damázio, JV Polla, S Citadin, LA de Luca, AS Barcellos, ML Garcez, J Quevedo, J Budni, AI Zugno
Molecular Neurobiology 2017
Genderspecific differences of homocysteinemia and its influence on oxidative stress parameters and endothelial function in patients with stable forms of coronary heart disease
OL Belaya, KY Bondar, LI Markova, ZV Kuropteva, LM Baider, IS Mikhailova, YV Kuznetsova
2017
Effects of atorvastatin and simvastatin on oxidative stress in diet-induced hyperhomocysteinemia in Wistar albino rats: a comparative study.
Nikolic T, Zivkovic V, Srejovic I, Stojic I, Jeremic N, Jeremic J, Radonjic K, Stankovic S, Obrenovic R, Djuric D, Jakovljevic V
Molecular and Cellular Biochemistry 2017
The Evaluation of Folic Acid-Deficient or Folic Acid-Supplemented Diet in the Gestational Phase of Female Rats and in Their Adult Offspring Subjected to an Animal Model of Schizophrenia.
Canever L, Alves CSV, Mastella G, Damázio L, Polla JV, Citadin S, De Luca LA, Barcellos AS, Garcez ML, Quevedo J, Budni J, Zugno AI
Molecular Neurobiology 2017
Homocysteine, hyperhomocysteinemia and vascular contributions to cognitive impairment and dementia (VCID)
AH Hainsworth, NE Yeo, EM Weekman, DM Wilcock
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2016
Consequence of hyperhomocysteinaemia on α 1 -adrenoceptor-mediated contraction in the rat corpus cavernosum: the role of reactive oxygen species
H Côco, L Pernomian, KC Marchi, MS Gomes, CR de Andrade, LN Ramalho, CR Tirapelli, AM de Oliveira
Journal of Pharmacy and Pharmacology 2016
Challenges and opportunities for stem cell therapy in patients with chronic kidney disease
LT Hickson, A Eirin, LO Lerman
Kidney International 2016
One carbon metabolism and bone homeostasis and remodeling: A review of experimental research and population studies
E Feigerlova, L Demarquet, JL Guéant
Biochimie 2016
Polymorphisms of glutathione S-transferase and methylenetetrahydrofolate reductase genes in Moldavian patients with ulcerative colitis: Genotype-phenotype correlation
A Varzari, IV Deyneko, E Tudor, S Turcan
Meta Gene 2016
Homocysteine in Renal Injury
Y Long, J Nie
Kidney Diseases 2016
Possible Pharmacological Approach Targeting Endoplasmic Reticulum Stress to Ameliorate Leptin Resistance in Obesity
T Hosoi, K Ozawa
Frontiers in Endocrinology 2016
Relationship between MTHFR C677T and A1298C gene polymorphisms and complications of type 2 diabetes mellitus in an Emirati population
SW el Chehadeh, HF Jelinek, WA Mahmeed, GK Tay, UO Odama, GE Elghazali, HS Safar
Meta Gene 2016
Epigenética en la arteriosclerosis
M Guardiola, JC Vallvé, S Zaina, J Ribalta
Clínica e Investigación en Arteriosclerosis 2015
Homocysteine thiolactone and N-homocysteinylated protein induce pro-atherogenic changes in gene expression in human vascular endothelial cells
D Gurda, L Handschuh, W Kotkowiak, H Jakubowski
Amino Acids 2015
Pathological concentrations of homocysteine increases IL-1β production in macrophages in a P2X7, NF-ĸB, and erk-dependent manner
RF Zanin, LS Bergamin, FB Morrone, R Coutinho-Silva, AT de Wyse, AM Battastini
Purinergic Signalling 2015
Black tea protects against hypertension-associated endothelial dysfunction through alleviation of endoplasmic reticulum stress
WS Cheang, CY Ngai, YY Tam, XY Tian, WT Wong, Y Zhang, CW Lau, ZY Chen, ZX Bian, Y Huang, FP Leung
Scientific Reports 2015
The potential physiological crosstalk and interrelationship between two sovereign endogenous amines, melatonin and homocysteine
R Paul, A Borah
Life Sciences 2015
WNT-1 inducible signaling pathway protein-1 enhances growth and tumorigenesis in human breast cancer
KC Chiang, CN Yeh, LC Chung, TH Feng, CC Sun, MF Chen, YY Jan, TS Yeh, SC Chen, HH Juang
Scientific Reports 2015
Functional variants in CYP1B1, KRAS and MTHFR genes are associated with shorter telomere length in postmenopausal women
JZ Cerne, M Pohar-Perme, P Cerkovnik, K Gersak, S Novakovic
Mechanisms of Ageing and Development 2015
Homocysteine, methylenetetrahydrofolate reductase, folate status and atherothrombosis: A mechanistic and clinical perspective
F Santilli, G Davì, C Patrono
Vascular Pharmacology 2015
Role of folate-homocysteine pathway gene polymorphisms and nutritional cofactors in Down syndrome: A triad study
KK Sukla, SK Jaiswal, AK Rai, OP Mishra, V Gupta, A Kumar, R Raman
Human Reproduction 2015
Overexpression of N‑myc downstream‑regulated gene�1 inhibits human glioma proliferation and invasion via phosphoinositide 3‑kinase/AKT pathways
W Ma, M Na, C Tang, H Wang, Z Lin
Molecular medicine reports 2015
Contra-Directional Expression of Serum Homocysteine and Uric Acid as Important Biomarkers of Multiple System Atrophy Severity: A Cross-Sectional Study
D Chen, X Wei, J Zou, R Wang, X Liu, X Xu, J Lu, Z Wang, B Tang, B Wang, K Jin, Q Wang
Frontiers in cellular neuroscience 2015
Heme Degradation by Heme Oxygenase Protects Mitochondria but Induces ER Stress via Formed Bilirubin
A Müllebner, R Moldzio, H Redl, A Kozlov, J Duvigneau
Biomolecules 2015
Elevated Homocysteine Levels Contribute to Larger Hematoma Volume in Patients with Intracerebral Hemorrhage
F Zhou, B chen, C Chen, J Huang, S Chen, F Guo, Z Hu
Journal of Stroke and Cerebrovascular Diseases 2015
Hypercysteinemia promotes atherosclerosis by reducing protein S-nitrosylation
Y Chen, R Liu, G Zhang, Q Yu, M Jia, C Zheng, Y Wang, C Xu, Y Zhang, E Liu
Biomedicine & Pharmacotherapy 2015
Markers of Oxidative Stress in Pregnant Women with Sleep Disturbances
S Rajendiran, SK A, A Nimesh, S S, PH Ananthanarayanan, P Dhiman
Oman Medical Journal 2015
Protein N-Homocysteinylation: From Cellular Toxicity to Neurodegeneration
GS Sharma, T Kumar, TA Dar, LR Singh
Biochimica et Biophysica Acta (BBA) - General Subjects 2015
Comprehensive Physiology
KS McCully
Comprehensive Physiology 2015
Gas-Phase Unimolecular Dissociation Reveals Dominant Base Property of Protonated Homocysteine Sulfinyl Radical Ions
CB Love-Nkansah, L Tan, JS Francisco, Y Xia
Chemistry - A European Journal 2015
DNA hypermethylation in hyperhomocysteinemia contributes to abnormal extracellular matrix metabolism in the kidney
S Pushpakumar, S Kundu, N Narayanan, U Sen
The FASEB Journal 2015
International Review of Cell and Molecular Biology
KE Latham
International review of cell and molecular biology 2015
Bovine Theileriosis: Effects on the Status of Thyroid Hormones, Homocystein, Serum Lipids and Lipoproteins
SM Razavi, B Moghaddas, E Rakhshande, S Nazifi
Research Journal of Parasitology 2015
Nutrition Management of Inherited Metabolic Diseases
LE Bernstein, F Rohr, JR Helm
2015
Global gene expression analysis reveals a link between NDRG1 and vesicle transport
HA Askautrud, E Gjernes, G Gunnes, M Sletten, DT Ross, AL Børresen-Dale, N Iversen, MA Tranulis, E Frengen
PloS one 2014
Metabolic Syndrome: An Important Risk Factor for Parkinson's Disease
P Zhang, B Tian
Oxidative Medicine & Cellular Longevity 2014
NDRG1 Deficiency Attenuates Fetal Growth and the Intrauterine Response to Hypoxic Injury
J Larkin, B Chen, XH Shi, T Mishima, K Kokame, Y Barak, Y Sadovsky
Endocrinology 2014
Contemporary Issues Surrounding Folic Acid Fortification Initiatives
JH Choi, Z Yates, M Veysey, YR Heo, M Lucock
Preventive Nutrition and Food Science 2014
Anethole dithiolethione lowers the homocysteine and raises the glutathone levels in solid tissues and plasma of rats: A novel non-vitamin homocysteine-lowering agent
D Giustarini, P Fanti, A Sparatore, E Matteucci, R Rossi
Biochemical Pharmacology 2014
Homocysteine contribution to DNA damage in cystathionine β-synthase-deficient patients
CS Vanzin, V Manfredini, AE Marinho, GB Biancini, GS Ribas, M Deon, AT de Wyse, M Wajner, CR Vargas
Gene 2014
Metformin Eased Cognitive Impairment Induced by Chronic L-methionine Administration: Potential Role of Oxidative Stress
KH Alzoubi, OF Khabour, SI Al-Azzam, MH Tashtoush, NM Mhaidat
Current neuropharmacology 2014
Cardiovascular co-morbidity in chronic kidney disease: Current knowledge and future research needs
H Alani
World Journal of Nephrology 2014
Effects of Calcineurin Inhibitors on Paraoxonase and Arylesterase Activity After a Kidney Transplant
S Kahvecioglu, A Ersoy, M Gullulu, M Dirican
Experimental and Clinical Transplantation 2014
Effect of choline on antioxidant defenses and gene expressions of Nrf2 signaling molecule in the spleen and head kidney of juvenile Jian carp (Cyprinus carpio var. Jian)
P Wu, WD Jiang, Y Liu, GF Chen, J Jiang, SH Li, L Feng, XQ Zhou
Fish & Shellfish Immunology 2014
Hyperhomocysteinemia Is a Risk Factor for Alzheimer's Disease in an Algerian Population
K Nazef, M Khelil, H Chelouti, G Kacimi, M Bendini, M Tazir, S Belarbi, ME Cherifi, B Djerdjouri
Archives of Medical Research 2014
A putative role for homocysteine in the pathophysiology of acute bacterial meningitis in children
R Coimbra, BF Calegare, TM Candiani, V D’Almeida
BMC clinical pathology 2014
Folate administration decreases oxidative status and blood pressure in postmenopausal women
A Cagnacci, M Cannoletta, A Xholli, I Piacenti, F Palma, B Palmieri
European Journal of Nutrition 2014
Superoxide Dismutase: Therapeutic Targets in SOD Related Pathology
F Cristiana, A Elena, Z Nina
Health 2014
Folate administration decreases oxidative status and blood pressure in postmenopausal women.
Cagnacci A, Cannoletta M, Xholli A, Piacenti I, Palma F, Palmieri B
European Journal of Nutrition 2014
Endothelial dysfunction: the link between homocysteine and hydrogen sulfide.
Pushpakumar S, Kundu S, Sen U
Current medicinal chemistry 2014
Homocysteine-induced apoptosis in endothelial cells coincides with nuclear NOX2 and peri-nuclear NOX4 activity
JA Sipkens, N Hahn, CS van Brand, C Meischl, SA Cillessen, DE Smith, LJ Juffermans, RJ Musters, D Roos, C Jakobs, HJ Blom, YM Smulders, PA Krijnen, CD Stehouwer, JA Rauwerda, VW van Hinsbergh, HW Niessen
Cell Biochemistry and Biophysics 2013
Selective homocysteine lowering gene transfer improves infarct healing, attenuates remodelling, and enhances diastolic function after myocardial infarction in mice
I Muthuramu, F Jacobs, N Singh, SC Gordts, BD Geest
PloS one 2013
Defective homocysteine metabolism: potential implications for skeletal muscle malfunction
S Veeranki, SC Tyagi
International journal of molecular sciences 2013
Decreased vitamin B12 availability induces ER stress through impaired SIRT1-deacetylation of HSF1
R Ghemrawi, S Pooya, S Lorentz, G Gauchotte, C Arnold, JL Gueant, SF Battaglia-Hsu
Cell Death and Disease 2013
Dynamics of the enzymatic antioxidants during experimental caprine coccidiosis
E Rakhshandehroo, SM Razavi, S Nazifi, M Farzaneh, N Mobarraei
Parasitology Research 2013
The potential role of homocysteine mediated DNA methylation and associated epigenetic changes in abdominal aortic aneurysm formation
SM Krishna, A Dear, JM Craig, PE Norman, J Golledge
Atherosclerosis 2013
Homocysteine induces cerebral endothelial cell death by activating the acid sphingomyelinase ceramide pathway
JT Lee, GS Peng, SY Chen, CH Hsu, CC Lin, CA Cheng, YD Hsu, JC Lin
Progress in Neuro-Psychopharmacology and Biological Psychiatry 2013
Nutrition and Type 2 Diabetes: Etiology and Prevention
S Liu, Y Song
Nutrition and Type 2 Diabetes: Etiology and Prevention 2013
Phytoestrogen α-Zearalanol attenuates homocysteine-induced apoptosis in human umbilical vein endothelial cells
T Liu, DD Hou, Q Zhao, W Liu, PP Zhen, JP Xu, K Wang, HX Huang, X Li, H Zhang, HB Xu, W Wang
BioMed Research International 2013
Association of genetic polymorphism of PPARγ-2, ACE, MTHFR, FABP-2 and FTO genes in risk prediction of type 2 diabetes mellitus
S Abbas, ST Raza, F Ahmed, A Ahmad, S Rizvi, F Mahdi
Journal of Biomedical Science 2013
Methoxistasis: Integrating the Roles of Homocysteine and Folic Acid in Cardiovascular Pathobiology
J Joseph, J Loscalzo
Nutrients 2013
N-myc downstream-regulated gene 1: Diverse and complicated functions in human hepatocellular carcinoma (Review)
Y Song, L Cao
Oncology Letters 2013
The expression and localization of N-myc downstream-regulated gene 1 in human trophoblasts
XH Shi, JC Larkin, B Chen, Y Sadovsky
PloS one 2013
N-myc downstream regulated 1 (NDRG1) is regulated by eukaryotic initiation factor 3a (eIF3a) during cellular stress caused by iron depletion
DJ Lane, F Saletta, YS Rahmanto, Z Kovacevic, DR Richardson
PloS one 2013
Effect of Nrf2 activators on release of glutathione, cysteinylglycine and homocysteine by human U373 astroglial cells
ML Steele, S Fuller, M Patel, C Kersaitis, L Ooi, G Münch
Redox Biology 2013
Homocysteine induces heme oxygenase-1 expression via transcription factor Nrf2 activation in HepG2 cell
M Mani, T Golmohammadi, S Khaghani, Z Zamani, K Azadmanesh, R Meshkini, P Pasalar
Iranian Biomedical Journal 2013
FOXD3 is a novel tumor suppressor that affects growth, invasion, metastasis and angiogenesis of neuroblastoma
D Li, H Mei, M Qi, D Yang, X Zhao, X Xiang, J Pu, K Huang, L Zheng, Q Tong
Oncotarget 2013
Homocysteine Induces Heme Oxygenase-1 Expression via Transcription Factor Nrf2 Activation in HepG2 Cells
M Mani, T Golmohammadi, S Khaghani, Z Zamani, K Azadmanesh, R Meshkani, P Pasalar
Iranian Biomedical Journal 2013
Selective Homocysteine Lowering Gene Transfer Improves Infarct Healing, Attenuates Remodelling, and Enhances Diastolic Function after Myocardial Infarction in Mice
I Muthuramu, F Jacobs, N Singh, SC Gordts, BD Geest, GE Gonzalez
PloS one 2013
Dynamics of the enzymatic antioxidants during experimental caprine coccidiosis.
Rakhshandehroo E, Razavi SM, Nazifi S, Farzaneh M, Mobarraei N
Parasitology Research 2013
Homocysteinylated Albumin Promotes Increased Monocyte-Endothelial Cell Adhesion and Up-Regulation of MCP1, Hsp60 and ADAM17
R Capasso, I Sambri, A Cimmino, S Salemme, C Lombardi, F Acanfora, E Satta, DL Puppione, AF Perna, D Ingrosso
PloS one 2012
S-adenosyl-L-homocysteine hydrolase and methylation disorders: yeast as a model system
O Tehlivets, N Malanovic, M Visram, T Pavkov-Keller, W Keller
Biochimica et Biophysica Acta 2012
Homocysteine as a potential biochemical marker for depression in elderly stroke survivors
MC Pascoe, SG Crewther, LM Carey, K Noonan, DP Crewther, T Linden
Food & Nutrition Research 2012
Relationship between paraoxonase and homocysteine: crossroads of oxidative diseases
N Yilmaz
Archives of Medical Science : AMS 2012
Serum homocysteine and folate concentrations among a US cohort of adolescents before and after folic acid fortification
DA Enquobahrie, HA Feldman, DH Hoelscher, LM Steffen, LS Webber, MM Zive, EB Rimm, MJ Stampfer, SK Osganian
Public Health Nutrition 2012
Oxidative stress and platelet activation in subjects with moderate hyperhomocysteinaemia due to MTHFR 677 C →T polymorphism:
A Dragani, A Falco, F Santilli, S Basili, G Rolandi, L Cerasa, S Lattanzio, G Ciabattoni, C Patrono, G Davì
Thrombosis and Haemostasis 2012
Methodology for a rapid and simultaneous determination of total cysteine, homocysteine, cysteinylglycine and glutathione in plasma by isocratic RP-HPLC
R Ferin, ML Pavão, J Baptista
Journal of Chromatography B 2012
Serum homocysteine, arginine, citrulline and asymmetric dimethyl arginine levels, and histopathologic examination of the abdominal aorta in rats exposed to acrylamide
A Toker, FH Yerlikaya, Y Yener, H Toy
Biotechnic & Histochemistry 2012
Association of Differentiation-Related Gene-1 (DRG1) with Breast Cancer Survival and in Vitro Impact of DRG1 Suppression
RM Baig, AJ Sanders, MA Kayani, WG Jiang
Cancers 2012
Autophagy mechanism of right ventricular remodeling in murine model of pulmonary artery constriction
N Qipshidze, N Tyagi, N Metreveli, D Lominadze, SC Tyagi
American journal of physiology. Heart and circulatory physiology 2012
Homocysteine, folate, vitamin B-12, and physical function in older adults: cross-sectional findings from the Singapore Longitudinal Ageing Study
TP Ng, KC Aung, L Feng, SC Scherer, KB Yap
The American journal of clinical nutrition 2012
Second-hand tobacco smoke and children
EM Al-Sayed, KS Ibrahim
Toxicology and industrial health 2012
Homocysteine promotes human endothelial cell dysfunction via site-specific epigenetic regulation of p66shc
CS Kim, YR Kim, A Naqvi, S Kumar, TA Hoffman, SB Jung, A Kumar, BH Jeon, DM McNamara, K Irani
Cardiovascular Research 2011
Water Soluble Vitamins
O Stanger
2011
Water Soluble Vitamins
O Stanger
2011
Water Soluble Vitamins
O Stanger
2011
Water Soluble Vitamins
O Stanger
2011
Water Soluble Vitamins
O Stanger
2011
Water Soluble Vitamins
O Stanger
2011
Homocysteine as a Risk Factor for Atherosclerosis: Is Its Conversion to S-Adenosyl-L-Homocysteine the Key to Deregulated Lipid Metabolism?
O Tehlivets
Journal of Lipids 2011
Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and high plasma homocysteine in chronic hepatitis C (CHC) infected patients from the Northeast of Brazil
ER Siqueira, CP Oliveira, MT Muniz, F Silva, LM Pereira, FJ Carrilho
Nutrition Journal 2011
Advances in Clinical Chemistry
M Mahler
Advances in Clinical Chemistry Volume 54 2011
Methylenetetrahydrofolate reductase C677T polymorphism is not associated with male infertility in a South Indian population
GT Vani, N Mukesh, PR Devi, PU Rani, PP Reddy
Andrologia 2011
Experimental evidence of oxidative stress in plasma of homocystinuric patients: A possible role for homocysteine
CS Vanzin, GB Biancini, A Sitta, CA Wayhs, IN Pereira, F Rockenbach, SC Garcia, AT de Wyse, IV Schwartz, M Wajner, CR Vargas
Molecular Genetics and Metabolism 2011
Bisphosphonates in phenytoin-induced bone disorder
S Khanna, KK Pillai, D Vohora
Bone 2011
Relationship Between Plasma Homocysteine Levels and Congestive Heart Failure in Patients With Acute Myocardial Infarction
T Washio, K Nomoto, I Watanabe, S Tani, K Nagao, A Hirayama
International Heart Journal 2011
Chronic Homocysteine Exposure Upregulates Endothelial Adhesion Molecules and Mediates Leukocyte: Endothelial Cell Interactions under Flow Conditions
K Alkhoury, SM Parkin, S Homer-Vanniasinkam, AM Graham
European Journal of Vascular and Endovascular Surgery 2011
Evaluation of MTHFR C677T polymorphism in ischemic and hemorrhagic stroke patients. A case–control study in a Northern Indian population
BI Somarajan, J Kalita, B Mittal, UK Misra
Journal of the Neurological Sciences 2011
Methionine diet-induced hyperhomocysteinemia accelerates cerebral aneurysm formation in rats
Y Xu, Y Tian, HJ Wei, JF Dong, JN Zhang
Neuroscience Letters 2011
Effect of red wine polyphenol dietary supplementation on two phase II enzymes in liver of hyperhomocysteinemic mice
C Noll, J Dairou, C Ripoll, JL Paul, JM Dupret, JM Delabar, F Rodrigues-Lima, N Janel
Food and Chemical Toxicology 2011
Hypothesis: Hyperhomocysteinemia is an indicator of oxidant stress
M Hoffman
Medical Hypotheses 2011
Skin advanced glycation end-product accumulation is negatively associated with calcaneal osteo-sono assessment index among non-diabetic adult Japanese men
H Momma, K Niu, Y Kobayashi, L Guan, M Sato, H Guo, M Chujo, A Otomo, C Yufei, H Tadaura, T Saito, T Mori, T Miyata, R Nagatomi
Osteoporosis International 2011
Chronic hyperhomocysteinemia induces oxidative damage in the rat lung
AA Cunha, AG Ferreira, MJ Cunha, CD Pederzolli, DL Becker, JG Coelho, CS Dutra-Filho, AT Wyse
Molecular and Cellular Biochemistry 2011
The effects of homocysteine and folic acid on angiogenesis and VEGF expression during chicken vascular development
AM Oosterbaan, EA Steegers, NT Ursem
Microvascular Research 2011
The Indolic Diet-Derivative, 3,3′-Diindolylmethane, Induced Apoptosis in Human Colon Cancer Cells through Upregulation of NDRG1
A Lerner, M Grafi-Cohen, T Napso, N Azzam, F Fares
Journal of Biomedicine and Biotechnology 2011
Up-Regulation of NDRG2 in Senescent Lens Epithelial Cells Contributes to Age-Related Cataract in Human
ZF Zhang, J Zhang, YN Hui, MH Zheng, XP Liu, PF Kador, YS Wang, LB Yao, J Zhou
PloS one 2011
Role of Oxytocin in deceleration of early atherosclerotic inflammatory processes in adult male rats
MA Ahmed, GM Elosaily
International journal of clinical and experimental medicine 2011
Why Do Homocysteine-Lowering B Vitamin and Antioxidant E Vitamin Supplementations Appear To Be Ineffective in the Prevention of Cardiovascular Diseases?: Vitamin Substitution in the Prevention of CVD
B Debreceni, L Debreceni
Cardiovascular Therapeutics 2011
Autophagy mechanism of right ventricular remodeling in murine model of pulmonary artery constriction
N Qipshidze, N Tyagi, N Metreveli, D Lominadze, SC Tyagi
American journal of physiology. Heart and circulatory physiology 2011
Micronutrient Levels in Children Exposed to Secondhand Tobacco Smoke
KM Wilson, JN Finkelstein, AK Blumkin, D Best, JD Klein
Nicotine & Tobacco Research 2011
Methylenetetrahydrofolate Reductase Polymorphisms Are Related to Male Infertility in Brazilian Men
MM Gava, EO Chagas, B Bianco, DM Christofolini, AC Pompeo, S Glina, CP Barbosa
Genetic Testing and Molecular Biomarkers 2011
Asymmetric dimethylarginine as a risk marker for early-onset ischemic stroke in Indian population
SN Mamatha, D Nagaraja, M Philip, R Christopher
Clinica Chimica Acta 2011
Pediatric Dialysis
BA Warady, F Schaefer, SR Alexander
2011
Molecular Basis of Health and Disease
UN Das
2011
Indicators of a hemostasis in patients with hyperhomocysteinemia on a hemodialysis
UV Kharlamova, OY Ilyicheva
2011
Acute hyperhomocysteinemia alters the coagulation system and oxidative status in the blood of rats
AA da Cunha, E Scherer, MJ da Cunha, F Schmitz, FR Machado, DD Lima, D Delwing, AT Wyse
Molecular and Cellular Biochemistry 2011
Chronic hyperhomocysteinemia induces oxidative damage in the rat lung.
da Cunha AA, Ferreira AG, da Cunha MJ, Pederzolli CD, Becker DL, Coelho JG, Dutra-Filho CS, Wyse AT
Molecular and Cellular Biochemistry 2011
Protein Misfolding and Cellular Stress in Disease and Aging
P Bross, N Gregersen
2010
Protein Misfolding and Cellular Stress in Disease and Aging
P Bross, N Gregersen
2010
Protein Misfolding and Cellular Stress in Disease and Aging
P Bross, N Gregersen
2010
Protein Misfolding and Cellular Stress in Disease and Aging
P Bross, N Gregersen
2010
New hypotheses for the health-protective mechanisms of whole-grain cereals: what is beyond fibre?
A Fardet
Nutrition Research Reviews 2010
Treatment of Erectile Dysfunction Due to C677T Mutation of the MTHFR Gene with Vitamin B6 and Folic acid in Patients Non Responders to PDE5i
F Lombardo, P Tsamatropoulos, E Piroli, F Culasso, EA Jannini, F Dondero, A Lenzi, L Gandini
Journal of Sexual Medicine 2010
Acute Liver Failure and Reversible Leukoencephalopthy in a Pediatric Patient With Homocystinuria
P Gupta, S Goyal, PE Grant, R Fawaz, J Lok, P Yager, A Sharma, K Sassower, N Noviski, M Browning, I Sahai
Journal of Pediatric Gastroenterology and Nutrition 2010
Increased levels of homocysteine in patients with ulcerative colitis
S Akbulut, E Altiparmak, F Topal, E Ozaslan, M Kucukazman, O Yonem
World journal of gastroenterology : WJG 2010
Plasma oxidized LDL and thiol-containing molecules in patients with exudative age-related macular degeneration
A Javadzadeh, A Ghorbanihaghjo, E Bahreini, N Rashtchizadeh, H Argani, S Alizadeh
Molecular vision 2010
Relationships of Plasma Homocysteine Concentration and Oxidative Stress Markers in Korean Collage Students
JS Kim, E Park, H Min, MH Kang
The Korean Journal of Nutrition 2010
Chronic treatment with cyclosporine affects systemic purinergic parameters, homocysteine levels and vascular disturbances in rats
AE Böhmer, LM Brum, DG Souza, AM Corrêa, JP Oses, GG Viola, PJ Saraiva, D Driemeier, LV Portela, DO Souza
Chemico-Biological Interactions 2010
Long-term cyclosporine treatment in non-transplanted rats and metabolic risk factors of vascular diseases
AE Böhmer, DG Souza, G Hansel, LM Brum, LV Portela, DO Souza
Chemico-Biological Interactions 2010
Role of NMDA receptor in homocysteine-induced activation of Mitogen-Activated Protein Kinase and Phosphatidyl Inositol 3-Kinase pathways in cultured human vascular smooth muscle cells
G Doronzo, I Russo, PD Mese, M Viretto, L Mattiello, M Trovati, G Anfossi
Thrombosis Research 2010
Effect of an antioxidant drink on homocysteine levels in Alzheimer's patients
JM Morillas-Ruiz, JM Rubio-Perez, MD Albaladejo, P Zafrilla, S Parra, ML Vidal-Guevara
Journal of the Neurological Sciences 2010
Hiperhomocisteinemia. Panorama actual y contribución del ratón a su estudio
M Nuño-Ayala, R Carnicer, MA Guzmán, N Guillén, MÁ Navarro, C Arnal, J Osada
Clínica e Investigación en Arteriosclerosis 2010
Effect of Estrogen on Mitochondrial Function and Intracellular Stress Markers in Rat Liver and Kidney following Trauma-Hemorrhagic Shock and Prolonged Hypotension
AV Kozlov, JC Duvigneau, TC Hyatt, R Raju, T Behling, RT Hartl, K Staniek, I Miller, W Gregor, H Redl, IH Chaudry
Molecular Medicine 2010
Vitamins & Hormones
KJ Hare, FK Knop
Vitamins & Hormones 2010
Changes in the metabolic footprint of placental explant-conditioned medium cultured in different oxygen tensions from placentas of small for gestational age and normal pregnancies
RP Horgan, DI Broadhurst, WB Dunn, M Brown, AE Heazell, DB Kell, PN Baker, LC Kenny
Placenta 2010
Rôle de l’homocystéine en pathologie
C jaeger, N Fraoucene, E Voronska, P Cherin
Médecine & Longévité 2010
Nutritional and oxidative status in occupational obese subjects
L Vigna, C Novembrino, R Giuseppe, F Liso, D Sommaruga, G Agnelli, V Belluigi, L Riboldi, F Bamonti
Mediterranean Journal of Nutrition and Metabolism 2010
Challenges of long-term nutrition intervention studies on cognition: discordance between observational and intervention studies of vitamin B12 and cognition: Nutrition Reviews©, Vol. 68, No. S1
C McCracken
Nutrition Reviews 2010
Association of maternal folate nutrition and serum C-reactive protein concentrations with gestational age at delivery
H Kim, JY Hwang, EH Ha, H Park, M Ha, SJ Lee, YC Hong, N Chang
European Journal of Clinical Nutrition 2010
Homocysteine Enhances Transmigration of Rat Monocytes through a Brain Capillary Endothelial Cell Monolayer via ICAM-1
Lindsay A. Hohsfield, Christian Humpel
Current neurovascular research 2010
Influence of thiol stress on oxidative phosphorylation and generation of ROS in Streptomyces coelicolor
HJ Vekaria, RP Chivukula
Journal of Biophysical Chemistry 2010
Biochemical risk factors of vascular complications in children with type 2 diabetes mellitus in the late postoperative period following reconstructive surgery
AV Pokrovskiĭ, RM Doguzhieva, VS Demidova, AN Lebedeva
Problems of Endocrinology 2010
The treatment of hyperhomocysteinemia
BA Maron, J Loscalzo
Annual Review of Medicine 2009
Macrophage Apoptosis in Atherosclerosis: Consequences on Plaque Progression and the Role of Endoplasmic Reticulum Stress
I Tabas
Antioxidants & Redox Signaling 2009
The methylenetetrahydrofolate reductase C677T mutation induces cell-specific changes in genomic DNA methylation and uracil misincorporation: a possible molecular basis for the site-specific cancer risk modification
KJ Sohn, H Jang, M Campan, DJ Weisenberger, J Dickhout, YC Wang, RC Cho, Z Yates, M Lucock, EP Chiang, RC Austin, SW Choi, PW Laird, YI Kim
International Journal of Cancer 2009
Contributions of hyperhomocysteinemia to atherosclerosis: Causal relationship and potential mechanisms
J Zhou, RC Austin
BioFactors 2009
Homocysteine-induced oxidative stress upregulates chymase in mouse mastocytoma cells
K Fujimi, Y Uehara, S Abe, A Kawamura, S Devarajan, S Miura, K Saku, H Urata
Hypertension Research 2009
Homocysteine and inflammation as main determinants of oxidative stress in the elderly
E Ventura, R Durant, A Jaussent, MC Picot, M Morena, S Badiou, AM Dupuy, C Jeandel, JP Cristol
Free radical biology & medicine 2009
Effect of folic Acid on hematological changes in methionine-induced hyperhomocysteinemia in rats
MN Ansari, GK Nigam, U Bhandari
Indian journal of pharmaceutical sciences 2009
H2S protects against methionine-induced oxidative stress in brain endothelial cells
N Tyagi, KS Moshal, U Sen, TP Vacek, M Kumar, WM Hughes, S Kundu, SC Tyagi
Antioxidants & Redox Signaling 2009
Kinetics of albumin homocysteinylation measured with matrix-assisted laser/desorption ionization mass spectrometry versus with a radioactive tracer
E Callegher, R Seraglia, M Vettore, L Puricelli, R Millioni, P Tessari
Rapid Communications in Mass Spectrometry 2009
Detection of aminothiols through surface-assisted laser desorption/ionization mass spectrometry using mixed gold nanoparticles
NC Chiang, CK Chiang, ZH Lin, TC Chiu, HT Chang
Rapid Communications in Mass Spectrometry 2009
Endogenous Elevation of Homocysteine Induces Retinal Neuron Death in the Cystathionine-β-Synthase Mutant Mouse
PS Ganapathy, B Moister, P Roon, BA Mysona, J Duplantier, Y Dun, TK Moister, MJ Farley, PD Prasad, K Liu, SB Smith
Investigative ophthalmology & visual science 2009
Quo Vadis: Whither Homocysteine Research?
J Joseph, DE Handy, J Loscalzo
Cardiovascular Toxicology 2009
ER Stress-Inducible Factor CHOP Affects the Expression of Hepcidin by Modulating C/EBPalpha Activity
SJ Oliveira, JP Pinto, G Picarote, VM Costa, F Carvalho, M Rangel, M Sousa, SF de Almeida
PloS one 2009
Homocysteine and serum lipids concentration in male war veterans with posttraumatic stress disorder
T Jendričko, A Vidović, M Grubišić-Ilić, Ž Romić, Z Kovačić, D Kozarić-Kovačić
Progress in Neuro-Psychopharmacology and Biological Psychiatry 2009
Comprehensive Vascular and Endovascular Surgery
BT Baxter, J MacTaggart
Comprehensive Vascular and Endovascular Surgery 2009
Folate in Health and Disease, Second Edition: Embryonic Consequences of Abnormal Folate Transport and Metabolism
D Wallis, J Ballard, G Shaw, E Lammer, R Finnell
Folate in Health and Disease, Second Edition 2009
Telomere Length in Lymphocytes of Older South Australian Men May Be Inversely Associated with Plasma Homocysteine
CF Bull, NJ O'Callaghan, G Mayrhofer, MF Fenech
Rejuvenation Research 2009
Relationship of Serum Homocysteine with Brachial-Ankle Pulse Wave Velocity in Middle Aged Women
BJ Park, HY Chun, AR Han, JA Lim, DC Lee, JY Shim, HR Lee
Korean Journal of Family Medicine 2009
The role of the thiol disufide system in the mechanism of oxidative stress and distress in HIV infection
VV Kostyushov, II Bokal
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry 2009
Molecular mechanisms of homocysteine toxicity
AA Boldyrev
Biochemistry (Moscow) 2009
Mitochondrial DNA deletions of blood lymphocytes as genetic markers of low folate-related mitochondrial genotoxicity in peripheral tissues
YF Chou, RF Huang
European Journal of Nutrition 2009
The factors that affect plasma homocysteine levels, pulse wave velocity and their relationship with cardiovascular disease indicators in peritoneal dialysis patients
S Ertek, AN Torun, K Ates
International Urology and Nephrology 2009
The Association between Cardiorespiratory Fitness, Inflammation Marker and Stroke Risk Factor in Chronic Stroke Patients
shinyuna, 임강일, 김효중
Journal of adapted physical activity and exercise 2009
Effects of hydrogen peroxide treatment on thiol contents in fresh-cut asparagus ( Asparagus officinalis ) spears
O Demrkol
International Journal of Food Sciences and Nutrition 2009
Mitochondrial DNA deletions of blood lymphocytes as genetic markers of low folate-related mitochondrial genotoxicity in peripheral tissues.
Chou YF, Huang RF
European Journal of Nutrition 2009
The factors that affect plasma homocysteine levels, pulse wave velocity and their relationship with cardiovascular disease indicators in peritoneal dialysis patients.
Ertek S, Torun AN, Ates K
International Urology and Nephrology 2009
Rho kinase inhibition in severe malaria: thwarting parasite-induced collateral damage to endothelia
Z Taoufiq, F Gay, J Balvanyos, L Ciceron, M Tefit, P Lechat, D Mazier
The Journal of Infectious Diseases 2008
Cystathionine beta synthase deficiency induces catalase-mediated hydrogen peroxide detoxification in mice liver
J Hamelet, V Seltzer, E Petit, C Noll, K Andreau, JM Delabar, N Janel
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2008
NF-kappaB activation is associated with homocysteine-induced injury in Neuro2a cells
N Ferlazzo, S Condello, M Currò, G Parisi, R Ientile, D Caccamo
BMC neuroscience 2008
Hyperhomocysteinemia induced by methionine supplementation does not independently cause atherosclerosis in C57BL/6J mice
J Zhou, GH Werstuck, Š Lhoták, YY Shi, V Tedesco, B Trigatti, J Dickhout, AK Majors, PM DiBello, DW Jacobsen, RC Austin
The FASEB Journal 2008
Effects of serum homocysteine and adiponectin levels on platelet aggregation in untreated patients with essential hypertension
H Ekmekçi, ÖB Ekmekçi, S Erdine, H Sönmez, Y Ataev, Z Öztürk, İİ Bütün, Ç Gürel, M Kucur, N Turfaner, T Ulutin, S Purisa, VA Vural
Journal of Thrombosis and Thrombolysis 2008
Waist-to-hip ratio correlates with homocysteine levels in male patients with coronary artery disease
YH Lin, KY Pao, WS Yang, VC Wu, YJ Chen, YL Lin, WS Tsai, IJ Tsai, CS Gau, JJ Hwang
Clinical Chemistry and Laboratory Medicine 2008
Pharmacogenetics of the neurodevelopmental impact of anticancer chemotherapy
P Robaey, M Krajinovic, S Marcoux, A Moghrabi
Developmental Disabilities Research Reviews 2008
Poly (ADP-ribose) Polymerase Inhibition Improves Endothelial Dysfunction Induced by Hyperhomocysteinemia in Rats
X Yu, X Cheng, J Xie, M Liao, R Yao, Y Chen, Y Ding, T Tang, Y Liao
Cardiovascular Drugs and Therapy 2008
Clinical relevance of plasma homocysteine levels in Taiwanese patients with coronary artery disease
ML Cheng, HY Ho, JF Lin, EC Chan, DT Chiu, YC Chen
BioFactors 2008
The effect of oral folic acid upon plasma homocysteine, endothelial function and oxidative stress in patients with type 1 diabetes and microalbuminuria
F Wotherspoon, DW Laight, C Turner, DR Meeking, SE Allard, LJ Munday, KM Shaw, MH Cummings
International Journal of Clinical Practice 2008
The effect of aqueous extract of Embelia ribes Burm on serum homocysteine, lipids and oxidative enzymes in methionine induced hyperhomocysteinemia
U Bhandari, MN Ansari, F Islam, CD Tripathi
Indian journal of pharmacology 2008
Effect of Nitrous Oxide on Neurologic and Neuropsychological Function after Intracranial Aneurysm Surgery
DG McGregor, WL Lanier, JJ Pasternak, DA Rusy, K Hogan, S Samra, B Hindman, MM Todd, DR Schroeder, EO Bayman, W Clarke, J Torner, J Weeks
Anesthesiology 2008
Plasma and Vitreous Homocysteine Concentrations in Patients With Proliferative Diabetic Retinopathy
O Aydemir, P Türkçüoğlu, M Güler, Ü Çeliker, B Üstündağ, T Yilmaz, K Metin
Retina 2008
Endoplasmic reticulum stress response in murine kidney exposed to acute hypobaric hypoxia
J Karar, KS Dolt, MA Pasha
FEBS Letters 2008
Dietary homocysteine promotes atherosclerosis in apoE-deficient mice by inducing scavenger receptors expression
P Thampi, BW Stewart, L Joseph, SB Melnyk, LJ Hennings, S Nagarajan
Atherosclerosis 2008
Approaching the End of the Homocysteine Hype?
G Sunder-Plassmann, WC Winkelmayer, M Födinger
American Journal of Kidney Diseases 2008
Extracellular superoxide dismutase (ecSOD) in vascular biology: an update on exogenous gene transfer and endogenous regulators of ecSOD
Z Qin, KJ Reszka, T Fukai, NL Weintraub
Translational Research 2008
Drug-induced pertubation of the aminothiol redox-status in patients with epilepsy: Improvement by B-vitamins
T Apeland, ES Frøyland, O Kristensen, RE Strandjord, MA Mansoor
Epilepsy Research 2008
Methylenetetrahydrofolate reductase gene, homocysteine and coronary artery disease: The A1298C polymorphism does matter. Inferences from a case study (Madeira, Portugal)
AI Freitas, I Mendonça, G Guerra, M Brión, RP Reis, A Carracedo, A Brehm
Thrombosis Research 2008
Homocysteine levels and leukocyte telomere length
JB Richards, AM Valdes, JP Gardner, BS Kato, A Siva, M Kimura, X Lu, MJ Brown, A Aviv, TD Spector
Atherosclerosis 2008
Effect of Anti-oxidant Treatment on Hyperhomocysteinemia-induced Myocardial Fibrosis and Diastolic Dysfunction
J Joseph, L Joseph, S Devi, RH Kennedy
The Journal of Heart and Lung Transplantation 2008
Lowering Homocysteine Decreases Levels and Expression of VEGF165 and Endostatin
HM Atta, MA El-Rehani, SA Raheim, AM Galal
Journal of Surgical Research 2008
The Use of an In Vivo Model to Study the Effects of Hyperhomocysteinaemia on Vascular Function
M Hansrani, G Stansby
Journal of Surgical Research 2008
ndrg4 is required for normal myocyte proliferation during early cardiac development in zebrafish
X Qu, H Jia, DM Garrity, K Tompkins, L Batts, B Appel, TP Zhong, HS Baldwin
Developmental Biology 2008
The in vivo Gene Expression Signature of Oxidative Stress
ES Han, FL Muller, VI Pérez, W Qi, H Liang, L Xi, C Fu, E Doyle, M Hickey, J Cornell, CJ Epstein, LJ Roberts, HV Remmen, A Richardson
Physiological genomics 2008
Homocysteine: The Rubik's Cube of Cardiovascular Risk Factors
RV Milani, CJ Lavie
Mayo Clinic Proceedings 2008
Folic acid and polyunsaturated fatty acids improve cognitive function and prevent depression, dementia, and Alzheimer's disease—But how and why?
UN Das
Prostaglandins, Leukotrienes and Essential Fatty Acids 2008
Reduced expression of N-Myc downstream-regulated gene 2 in human thyroid cancer
H Zhao, J Zhang, J Lu, X He, C Chen, X Li, L Gong, G Bao, Q Fu, S Chen, W Lin, H Shi, J Ma, X Liu, Q Ma, L Yao
BMC Cancer 2008
Homocysteine, Folate and Cognition in a Large Community-Based Sample of Elderly People – The 3C Dijon Study
JS Vidal, C Dufouil, V Ducros, C Tzourio
Neuroepidemiology 2008
Prenatal hyperhomocysteinemia as a model of oxidative stress of the brain
AV Makhro, AP Mashkina, OA Solenaya, OA Trunova, LS Kozina, AV Arutyunian, ER Bulygina
Bulletin of Experimental Biology and Medicine 2008
Evaluation of nitric oxide synthase activity, nitric oxide, and homocysteine levels in patients with active Behcet’s disease
S Taysi, RA Sari, H Dursun, A Yilmaz, M Keles, K Cayir, M Akyuz, A Uyanik, A Guvenc
Clinical Rheumatology 2008
The administration of folic acid reduces intravascular oxidative stress in diabetic rabbits
N Shukla, GD Angelini, JY Jeremy
Metabolism 2008
Homocysteine Toxicity in Connective Tissue: Theories, Old and New
JI Toohey
Connective Tissue Research 2008
Study on Homocysteine Levels and Methylenetetrahydrofolate Reductase Gene Variant (C677T) in a Population of Buenos Aires City
O Fridman, R Porcile, V Vanasco, MN Junco, L Gariglio, MA Potenzoni, I Bañes, A Morales
Clinical and Experimental Hypertension 2008
Hyperhomocysteinemia and Lower Extremity Wounds
EM Schwartzfarb, P Romanelli
The International Journal of Lower Extremity Wounds 2008
Mechanisms and potential therapeutic targets for folic acid in cardiovascular disease
AL Moens, CJ Vrints, MJ Claeys, JP Timmermans, HC Champion, DA Kass
American journal of physiology. Heart and circulatory physiology 2008
Homocysteine Activates Platelets In Vitro
IV Mohan, IA Jagroop, DP Mikhailidis, GP Stansby
Clinical and Applied Thrombosis/Hemostasis 2008
Association of Plasma Homocysteine and Macular Edema in Type 2 Diabetes Mellitus
E Aydin, HD Demir, H Ozyurt, I Etikan
European journal of ophthalmology 2008
Evaluation of nitric oxide synthase activity, nitric oxide, and homocysteine levels in patients with active Behcet's disease.
Taysi S, Sari RA, Dursun H, Yilmaz A, Keles M, Cayir K, Akyuz M, Uyanik A, Guvenc A
Clinical Rheumatology 2008
Should hyperhomocysteinemia be treated in patients with atherosclerotic disease?
BA Maron, J Loscalzo
Current Atherosclerosis Reports 2007
Vascular and Cellular Stress in Inflammatory Bowel Disease: Revisiting the Role of Homocysteine
L Peyrin-Biroulet, RM Rodriguez-Guéant, M Chamaillard, P Desreumaux, B Xia, JP Bronowicki, MA Bigard, JL Guéant
The American Journal of Gastroenterology 2007
Molecular Targeting of Proteins by L-Homocysteine: Mechanistic Implications for Vascular Disease
AV Glushchenko, DW Jacobsen
Antioxidants & Redox Signaling 2007
ER chaperones in mammalian development and human diseases
M Ni, AS Lee
FEBS Letters 2007
Homocysteine and Glutathione Peroxidase-1
E Lubos, J Loscalzo, DE Handy
Antioxidants & Redox Signaling 2007
Melatonin reduces protein and lipid oxidative damage induced by homocysteine in rat brain homogenates
S Ortega-Gutiérrez, L Fuentes-Broto, JJ García, M López-Vicente, E Martínez-Ballarín, FJ Miana-Mena, S Millán-Plano, RJ Reiter
Journal of Cellular Biochemistry 2007
Serum homocystein level and vascular thrombosis in patients with Beh�et disease
MA Nazarinia, E Aflaki, Z Habibaghahi, A Rajaee, GR Omrani
APLAR Journal of Rheumatology 2007
Hyperhomocysteinemia, DNA methylation and vascular disease
MS Jamaluddin, X Yang, H Wang
Clinical Chemistry and Laboratory Medicine 2007
Effects of homocysteine on the levels of caveolin-1 and eNOS in caveolae of human coronary artery endothelial cells
C Meye, J Schumann, A Wagner, P Gross
Atherosclerosis 2007
Elevated Homocysteine Levels in Patients with Slow Coronary Flow: Relationship with Helicobacter pylori Infection
H Evrengul, H Tanriverdi, O Kuru, Y Enli, D Yuksel, A Kilic, A Kaftan, S Kirac, M Kilic
Helicobacter 2007
Hyperhomocysteinemia and Cardiovascular Disorders: Is There a Correlation?
PB ., AP ., SS ., MS .
Trends in Medical Research 2007
Oxidative stress decreases extracellular homocysteine concentration in human hepatoma (HepG2) cell cultures
M Hultberg, B Hultberg
Chemico-Biological Interactions 2007
Pro-thrombotic and pro-oxidant effects of diet-induced hyperhomocysteinemia
DL Sauls, EK Arnold, CW Bell, JC Allen, M Hoffman
Thrombosis Research 2007
Homocysteine and Parkinson's disease: A dangerous liaison?
E Martignoni, C Tassorelli, G Nappi, R Zangaglia, C Pacchetti, F Blandini
Journal of the Neurological Sciences 2007
Correlations between homocysteine levels and atherosclerosis in Japanese type 2 diabetic patients
F Anan, T Masaki, Y Umeno, H Yonemochi, N Eshima, T Saikawa, H Yoshimatsu
Metabolism 2007
Interactive Effects of Homocysteine and Copper on Angiogenesis in Porcine Isolated Saphenous Vein
N Shukla, GD Angelini, JY Jeremy
The Annals of Thoracic Surgery 2007
Plasma concentrations of C-reactive protein and total homocysteine in relation to the severity and risk factors for cerebrovascular disease
MY Youssef, OA Mojiminiyi, NA Abdella
Translational Research 2007
Étude cas témoin évaluant l'incidence de l'hyperhomocystéinémie chez des patients porteurs de néoplasie dans un service de médecine interne
N Falvo, F Ghiringhelli, S Berthier, B Bonnotte, B Lorcerie
La Revue de Médecine Interne 2007
Genetically based hypertension generated through interaction of mild hypoalphalipoproteinemia and mild hyperhomocysteinemia:
R Carnicer, MA Navarro, JM Mainar, C Arnal, JC Surra, S Ac??n, A Sarr??a, F Blanco-Vaca, N Maeda, J Osada
Journal of Hypertension 2007
Glutamate-cysteine ligase polymorphism, hypertension, and male sex are associated with cardiovascular events. Biochemical and genetic characterization of Italian subpopulation
J Campolo, S Penco, E Bianchi, L Colombo, M Parolini, R Caruso, V Sedda, MC Patrosso, G Cighetti, A Marocchi, O Parodi
American Heart Journal 2007
Homocysteine-induced impairment of insulin secretion from clonal pancreatic BRIN-BD11 beta-cells is not prevented by catalase
S Patterson, PR Flatt, NH McClenaghan
Pancreas 2007
Prolonged exposure to homocysteine results in diminished but reversible pancreatic beta-cell responsiveness to insulinotropic agents
S Patterson, SM Scullion, JT McCluskey, PR Flatt, NH McClenaghan
Diabetes/Metabolism Research and Reviews 2007
Effect of Homocysteine-Induced Oxidative Stress on Endothelial Function in Coronary Slow-Flow
H Tanriverdi, H Evrengul, Y Enli, O Kuru, D Seleci, S Tanriverdi, N Tuzun, HA Kaftan, N Karabulut
Cardiology 2007
Serum γ-glutamyl transferase is associated with plasma total homocysteine in Japanese patients with type 2 diabetes
H Sakuta, T Suzuki, T Ito
Acta Diabetologica 2007
High Serum Homocysteine Levels Correlate with a Decrease in the Blood Flow Velocity of the Ophthalmic Artery in Highway Toll Collectors
R Memisogullari, H Yüksel, A Coskun, HK Yüksel, Ö Yazgan, C Bilgin
The Tohoku Journal of Experimental Medicine 2007
Homocysteine Modulates the CD40/CD40L System
C Prontera, N Martelli, V Evangelista, E D’Urbano, S Manarini, A Recchiuti, A Dragani, C Passeri, G Davì, M Romano
Journal of the American College of Cardiology 2007
Effect of Homocysteine on Nitric Oxide Production in Coronary Microvascular Endothelial Cells
A Erol, MG Çınar, C Can, M Olukman, S Ülker, S Koşay
Endothelium : journal of endothelial cell research 2007
Correlation of N-myc downstream-regulated gene 1 expression with clinical outcomes of colorectal cancer patients of different race/ethnicity
Minori Koshiji, Kensuke Kumamoto, Keiichirou Morimura, Yasufumi Utsumi, Michiko Aizawa, Masami Hoshino, Shinji Ohki, Seiichi Takenoshita, Max Costa, Thérèse Commes, David Piquemal, Curtis-C Harris, Kam-Meng Tchou-Wong
World journal of gastroenterology : WJG 2007
Handbook of Neurochemistry and Molecular Neurobiology
VH Routh, JJ McArdle, NM Sanders, Z Song, R Wang
Handbook of Neurochemistry and Molecular Neurobiology 2007
Associations of MTHFR DNMT3b 4977 bp deletion in mtDNA and GSTM1 deletion, and aberrant CpG island hypermethylation of GSTM1 in non-obstructive infertility in Indian men
VS Dhillon, M Shahid, SA Husain
Molecular Human Reproduction 2007
Folic acid improves vascular reactivity in humans: a meta-analysis of randomized controlled trials
A de Bree, LA van Mierlo, R Draijer
The American journal of clinical nutrition 2007
Homocysteine, vitamins, and vascular disease prevention
KS McCully
The American journal of clinical nutrition 2007
MTHFR C677T polymorphism, GSTM1 deletion and male infertility: a possible suggestion of a gene-gene interaction?
V Paracchini, S Garte, E Taioli
Biomarkers 2006
Iron sucrose augments homocysteine-induced endothelial dysfunction in normal subjects
H Zheng, X Huang, Q Zhang, SD Katz
Kidney International 2006
Comparative Study on in Vitro Effects of Homocysteine Thiolactone and Homocysteine on HUVEC Cells: Evidence for a Stronger Proapoptotic and Proinflammative Homocysteine Thiolactone
M Kerkeni, M Tnani, L Chuniaud, A Miled, K Maaroufi, F Trivin
Molecular and Cellular Biochemistry 2006
Evidence for associations between common polymorphisms of estrogen receptor β gene with homocysteine and nitric oxide
M Reimann, K Vafeiadou, WL Hall, J Dierkes, M Nilsson, K Dahlman-Wright, M Ferrari, U Huebner, J Hallund, S Bugel, F Branca, CM Williams, C Koebnick
Climacteric 2006
Hyperhomocysteinemia inhibits post-injury reendothelialization in mice
H TAN, X JIANG, F YANG, Z LI, D LIAO, J TRIAL, M MAGERA, W DURANTE, X YANG, H WANG
Cardiovascular Research 2006
Does oxidative stress change ceruloplasmin from a protective to a vasculopathic factor?
N Shukla, J Maher, J Masters, GD Angelini, JY Jeremy
Atherosclerosis 2006
Value of 99mTc-methoxyisobutylisonitrile (99mTc-MIBI) gated SPECT for the detection of silent myocardial ischemia in hemodialysis patients: clinical variables associated with abnormal test results
M Caglar, B Mahmoudian, K Aytemir, S Kahraman, M Arc, G Kabakc, E Karabulut
Nuclear Medicine Communications 2006
Homocysteine-Should We Screen and Treat in Preventive Cardiology Programs?
H Tran, GJ Hankey, JW Eikelboom
Journal of Cardiopulmonary Rehabilitation 2006
Elevation of plasma homocysteine by methionine loading increases the diastolic blood pressure response to exercise
SE Brett, BY Jiang, C Turner, JM Ritter, PJ Chowienczyk
Journal of Hypertension 2006
Activation of p38 MAPKinase/cPLA2 pathway in homocysteine-treated platelets
G Leoncini, D Bruzzese, MG Signorello
Journal of Thrombosis and Haemostasis 2006
Oxidative stress and oxidant signaling in obstructive sleep apnea and associated cardiovascular diseases
YJ Suzuki, V Jain, AM Park, RM Day
Free radical biology & medicine 2006
Plasma homocysteine, oxidative stress and endothelial function in patients with Type�1 diabetes mellitus and microalbuminuria
F Wotherspoon, DW Laight, DL Browne, C Turner, DR Meeking, SE Allard, LJ Munday, KM Shaw, MH Cummings
Diabetic Medicine 2006
Reactive oxygen species and erectile dysfunction: possible role of NADPH oxidase
JY Jeremy, RA Jones, AJ Koupparis, M Hotston, R Persad, GD Angelini, N Shukla
International Journal of Impotence Research 2006
Effect of methionine loading on pulse wave analysis in elderly volunteers
SR Hart, AA Mangoni, CG Swift, SH Jackson
Postgraduate medical journal 2006
Exfoliation and carotid stiffness
M Irkec
The British journal of ophthalmology 2006
ACUTE DILATORY AND NEGATIVE INOTROPIC EFFECTS OF HOMOCYSTEINE ARE INHIBITED BY AN ADENOSINE BLOCKER
RH Kennedy, R Owings, J Joseph, RB Melchert, M Hauer-Jensen, M Boerma
Clinical and Experimental Pharmacology and Physiology 2006
Penicillamine administration reverses the inhibitory effect of hyperhomocysteinaemia on endothelium-dependent relaxation and superoxide formation in the aorta of the rabbit
N Shukla, A Koupparis, RA Jones, GD Angelini, R Persad, JY Jeremy
European Journal of Pharmacology 2006
Plasma antioxidants in subjects before hematopoietic stem cell transplantation
AC White, AM Sousa, J Blumberg, HF Ryan, BL Fanburg, US Kayyali
Bone Marrow Transplantation 2006
Influence of combined methylenetetrahydrofolate reductase (MTHFR) and thymidylate synthase enhancer region (TSER) polymorphisms to plasma homocysteine levels in Korean patients with recurrent spontaneous abortion
NK Kim, YK Choi, MS Kang, DH Choi, SH Cha, MO An, S Lee, M Jeung, JJ Ko, D Oh
Thrombosis Research 2006
Cellular differentiation determines the expression of the hypoxia-inducible protein NDRG1 in pancreatic cancer
E Angst, S Sibold, C Tiffon, R Weimann, B Gloor, D Candinas, D Stroka
British Journal of Cancer 2006
Homocysteine
BA Maron, J Loscalzo
Clinics in Laboratory Medicine 2006
Homocysteine levels are associated with the results of 123I-metaiodobenzylguanidine myocardial scintigraphy in type 2 diabetic patients
F Anan, H Yonemochi, T Masaki, N Takahashi, M Nakagawa, N Eshima, T Saikawa, H Yoshimatsu
European Journal of Nuclear Medicine and Molecular Imaging 2006
Carotid intima???media thickness in coronary slow flow: relationship with plasma homocysteine levels:
H Tanriverdi, H Evrengul, S Tanriverdi, O Kuru, D Seleci, Y Enli, A Kaftan, M Kilic
Coronary Artery Disease 2006
Hyperhomocysteinemia correlates with insulin resistance and low-grade systemic inflammation in obese prepubertal children
R Martos, M Valle, R Morales, R Cañete, MI Gavilan, V Sánchez-Margalet
Metabolism 2006
Penicillamine administration reverses the inhibitory effect of hyperhomocysteinaemia on endothelium-dependent relaxation in the corpus cavernosum in the rabbit
AJ Koupparis, J Jeremy, G Angelini, R Persad, N Shukla
BJU International 2006
Lack of Significant Effects of Methionine Loading on Endothelial Function in Elderly Volunteers
SR Hart, AA Mangoni, CG Swift, SH Jackson
Heart, Lung and Circulation 2006
Avaliação da relação entre o polimorfismo C677T no gene para MTHFR e a concentração plasmática de homocisteína na doença arterial coronariana
MT Muniz, ER Siqueira, RA Fonseca, V DAlmeida, JK Hotta, JE Santos, MS Cavalcanti, CA Sampaio
Arquivos brasileiros de endocrinologia e metabologia 2006
Aged Garlic Extract Inhibits Homocysteine-Induced CD36 Expression and Foam Cell Formation in Human Macrophages
N Ide, C Keller, N Weiss
The Journal of nutrition 2006
Interaction of Plasma Homocysteine and Thyroid Hormone Concentrations in the Pathogenesis of the Slow Coronary Flow Phenomenon
H Evrengul, H Tanriverdi, Y Enli, O Kuru, D Seleci, M Bastemir, A Kilic, A Kaftan, M Kilic
Cardiology 2006
Global effects of homocysteine on transcription in Escherichia coli: induction of the gene for the major cold-shock protein, CspA
KR Fraser, NL Tuite, A Bhagwat, CP O'Byrne
Microbiology 2006
Antioxidant activity of vitamin B 6 delays homocysteine-induced atherosclerosis in rats
N Endo, K Nishiyama, A Otsuka, H Kanouchi, M Taga, T Oka
British Journal of Nutrition 2006
Cardiac neural crest
JZ Stoller, JA Epstein
Seminars in Cell & Developmental Biology 2005
Plasma homocysteine levels and the left ventricular systolic function in coronary artery disease patients
SW Bokhari, ZW Bokhari, JA Zell, DW Lee, DP Faxon
Coronary Artery Disease 2005
Comparison of Cytotoxicity of Cysteine and Homocysteine for Renal Epithelial Cells
T Nakanishi, ER Akabane, M Nanami, Y Kiyobayashi, R Moriguchi, Y Hasuike, Y Otaki, K Miyagawa, R Itahana, M Izumi
Nephron Experimental Nephrology 2005
Plasma homocysteine and markers for oxidative stress and inflammation in patients with coronary artery disease – a prospective randomized study of vitamin supplementation
T Jonasson, AK Öhlin, A Gottsäter, B Hultberg, H Öhlin
Clinical Chemistry and Laboratory Medicine 2005
MTHFR C677T polymorphism associates with unexplained infertile male factors
JH Park, HC Lee, YM Jeong, TG Chung, HJ Kim, NK Kim, SH Lee, S Lee
Journal of Assisted Reproduction and Genetics 2005
Is homocysteine important as risk factor for coronary heart disease?
M Cesari, GP Rossi, D Sticchi, AC Pessina
Nutrition, Metabolism and Cardiovascular Diseases 2005
The Role of Homocysteine in Multisystem Age-Related Problems: A Systematic Review
HK Kuo, FA Sorond, JH Chen, A Hashmi, WP Milberg, LA Lipsitz
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2005
Homocysteine and Redox Signaling
CG Zou, R Banerjee
Antioxidants & Redox Signaling 2005
Homocysteine alterations in experimental cholestasis and its subsequent cirrhosis
MR Ebrahimkhani, H Sadeghipour, M Dehghani, S Kiani, S Payabvash, K Riazi, H Honar, P Pasalar, N Mirazi, M Amanlou, H Farsam, AR Dehpour
Life Sciences 2005
Fluvastatin Ameliorates the Hyperhomocysteinemia-Induced Endothelial Dysfunction
H Morita, Y Saito, N Ohashi, M Yoshikawa, M Katoh, T Ashida, H Kurihara, T Nakamura, M Kurabayashi, R Nagai
Circulation Journal 2005
Polymorphisms of genes controlling homocysteine levels and IQ score following the treatment for childhood ALL
M Krajinovic, P Robaey, S Chiasson, E Lemieux-Blanchard, M Rouillard, M Primeau, FG Bournissen, A Moghrabi
Pharmacogenomics 2005
Homocysteine and heart failure: a review of investigations from the Framingham Heart Study
J Sundström, RS Vasan
Clinical Chemistry and Laboratory Medicine 2005
Hyperhomocysteinaemia in chronic liver diseases: role of disease stage, vitamin status and methylenetetrahydrofolate reductase genetics
P Ventura, MC Rosa, G Abbati, S Marchini, E Grandone, P Vergura, S Tremosini, ML Zeneroli
Liver International 2005
Glutathione Peroxidase-1 and Homocysteine for Cardiovascular Risk Prediction
R Schnabel, KJ Lackner, HJ Rupprecht, C Espinola-Klein, M Torzewski, E Lubos, C Bickel, F Cambien, L Tiret, T Münzel, S Blankenberg
Journal of the American College of Cardiology 2005
Association of the C677T and A1298C polymorphisms of methylenetetrahydrofolate reductase gene with schizophrenia: Association is significant in men but not in women
A Sazci, E Ergul, I Kucukali, I Kara, G Kaya
Progress in Neuro-Psychopharmacology and Biological Psychiatry 2005
Glutathione monoethyl ester improves functional recovery, enhances neuron survival, and stabilizes spinal cord blood flow after spinal cord injury in rats
G GuÍzar-Sahagún, A Ibarra, A Espitia, A MartÍnez, I Madrazo, RE Franco-Bourland
Neuroscience 2005
Elevated plasma homocysteine level in slow coronary flow
I Barutcu, AT Sezgin, N Sezgin, H Gullu, AM Esen, E Topal, R Ozdemir
International Journal of Cardiology 2005
Plasma total homocysteine and gallstone in middle-aged Japanese men
H Sakuta, T Suzuki
Journal of Gastroenterology 2005
Methylenetetrahydrofolate reductase 677 C-T and homocysteine levels in Turkish patients with pseudoexfoliation
ME Turacli, O Tekeli, F Ozdemir, N Akar
Clinical & Experimental Ophthalmology 2005
Mapping the Theories of Preeclampsia: The Role of Homocysteine:
LE Mignini, PM Latthe, J Villar, MD Kilby, G Carroli, KS Khan
Obstetrics & Gynecology 2005
Similar rhythms of seasonal conceptions in neural tube defects and schizophrenia: A hypothesis of oxidant stress and the photoperiod
G Marzullo, FC Fraser
Birth defects research. Part A, Clinical and molecular teratology 2005
Levels of homocysteine are inversely associated with cardiovascular fitness in women, but not in men: data from the National Health and Nutrition Examination Survey 1999-2002
HK Kuo, CJ Yen, JF Bean
Journal of Internal Medicine 2005
Homocysteine and gallstone diseases: is hyperhomocysteinemia a prerequisite for or secondary to gallstone formation?
S Tazuma
Journal of Gastroenterology 2005
Homocysteine-Lowering Therapy and Early Progression of Transplant Vasculopathy: A Prospective, Randomized, IVUS-Based Study
L Potena, F Grigioni, G Magnani, P Ortolani, F Coccolo, S Sassi, K Koessels, C Marrozzini, A Marzocchi, S Carigi, AC Musuraca, A Russo, C Magelli, A Branzi
American Journal of Transplantation 2005
Novel Deletion Mutations of the DAX1 (NR0B1) Gene in Two Taiwanese Families with X-Linked Adrenal Hypoplasia Congenita
WY Tsai, YC Tung
Journal of Pediatric Endocrinology and Metabolism 2005
Mutation C677T in the methylenetetrahydrofolate reductase gene is associated with male infertility in an Indian population1
K Singh, SK Singh, R Sah, I Singh, R Raman
International Journal of Andrology 2005
Preliminary Results of the Effect of Treatment of Hyperhomocysteinemia and Its Relationship With Inflammation, Coagulation Status, and Endothelial Function After Renal Transplantation
J Manrique, A Diáz, JJ Gavira, A Hernández, D Pujante, P Errasti
Transplantation Proceedings 2005
The effects of a Chinese medicinal suppository (Vitalliver) on insulin-like growth factor 1 and homocysteine in patients with hepatitis B infection
SH Chui, K Chan, AK Chui, LS Shek, RN Wong
Phytotherapy research : PTR 2005
Homocysteine and vitamin status in healthy Thai smokers
K Suriyaprom, R Tungtrongchitr, P Pongpaew, B Phonrat, T Harnroongroj, N Vudhivai, A Tungtrongchitr, S Paksanont, S Pooudong, FP Schelp
Journal of nutritional & environmental medicine 2005
Hyperhomocysteinemia in ulcerative colitis is related to folate levels
Petros Zezos, Georgia Papaioannou, Nikolaos Nikolaidis, Themistoclis Vasiliadis, Olga Giouleme, Nikolaos Evgenidis
World journal of gastroenterology : WJG 2005
Hyperhomocyst(e)inemia impairs angiogenesis in a murine model of limb ischemia
M Bosch-Marcé, R Pola, AB Wecker, M Silver, A Weber, C Luedemann, C Curry, T Murayama, M Kearney, Y Yoon, MR Malinow, T Asahara, JM Isner, DW Losordo
Vascular medicine (London, England) 2005
Folic Acid Supplementation Can Reduce the Endothelial Damage in Rat Brain Microvasculature Due to Hyperhomocysteinemia
H Lee, J Kim, HJ Kim, I Lee, N Chang
The Journal of nutrition 2005
Homocysteine inhibits store-mediated calcium entry in human endothelial cells: Evidence for involvement of membrane potential and actin cytoskeleton
HS Zhang, JH Xiao, EH Cao, JF Qin
Molecular and Cellular Biochemistry 2005
Quantification of Thiol-Containing Amino Acids Linked by Disulfides to LDL
A Zinellu, S Sotgia, L Deiana, C Carru
Clinical chemistry 2005
Relationship of Plasma Homocysteine with the Severity of Chronic Heart Failure
M Herrmann, I Kindermann, S Müller, T Georg, M Kindermann, M Böhm, W Herrmann
Clinical chemistry 2005
MTHFR C677T polymorphism associates with unexplained infertile male factors.
Park JH, Lee HC, Jeong YM, Chung TG, Kim HJ, Kim NK, Lee SH, Lee S
Journal of Assisted Reproduction and Genetics 2005
High levels of homocysteine inhibit lysyl oxidase (LOX) and downregulate LOX expression in vascular endothelial cells
B Raposo, C Rodríguez, J Martínez-González, L Badimon
Atherosclerosis 2004
Effect of Mthfr genotype on diet-induced hyperhomocysteinemia and vascular function in mice
AM Devlin, E Arning, T Bottiglieri, FM Faraci, R Rozen, SR Lentz
Blood 2004
No Evidence for Oxidative Stress as a Mechanism of Action of Hyperhomocysteinemia in Humans
JM Huerta, S González, S Fernández, ÁM Patterson, C Lasheras
Free Radical Research 2004
Hyperhomocysteinemia, endoplasmic reticulum stress, and alcoholic liver injury.
Ji C, Kaplowitz N
World Journal of Gastroenterology 2004
Functional foods, cardiovascular disease and diabetes
E Herrera, PF Dodds
Functional foods, cardiovascular disease and diabetes 2004
Hyperhomocysteinemia in patients with Behçet’s disease: is it due to inflammation or therapy?
Z Yesilova, S Pay, C Oktenli, U Musabak, K Saglam, SY Sanisoglu, K Dagalp, MK Erbil, IH Kocar
Rheumatology International 2004
Acute hyperhomocysteinemia induces a reduction in arterial distensibility and compliance
G Arcaro, C Fava, R Dagradi, G Faccini, S Gaino, M Degan, C Lechi, A Lechi, P Minuz
Journal of Hypertension 2004
Impairment of coronary circulation by acute hyperhomocysteinaemia and reversal by antioxidant vitamins
A Coppola, C Astarita, E Liguori, D Fontana, M Oliviero, K Esposito, L Coppola, D Giugliano
Journal of Internal Medicine 2004
Altered platelet reactivity in peripheral vascular disease complicated with elevated plasma homocysteine levels
R Riba, A Nicolaou, M Troxler, S Homer-Vaniasinkam, KM Naseem
Atherosclerosis 2004
Acute hyperhomocysteinemia decreases NO bioavailability in healthy adults
SC Romerio, L Linder, J Nyfeler, M Wenk, P Litynsky, R Asmis, WE Haefeli
Atherosclerosis 2004
Homocysteine levels in women with antiphospholipid syndrome and normal fertile controls
RM Lee, MA Brown, K Ward, L Nelson, DW Branch, RM Silver
Journal of Reproductive Immunology 2004
Effect of acute hyperhomocysteinemia on coronary flow reserve in healthy adults
L Ascione, MD Michele, M Accadia, S Rumolo, C Sacra, VA Ortali, L Inserviente, M Petti, G Russo, B Tuccillo
Journal of the American Society of Echocardiography 2004
Homocysteine Levels, Haemostatic Risk Factors and Patency Rates after Endovascular Treatment of the Above-Knee Femoro-Popliteal Artery
E Laxdal, GE Eide, J Wirsching, GL Jenssen, T Jonung, G Pedersen, SR Amundsen, E Dregelid, S Aune
European Journal of Vascular and Endovascular Surgery 2004
Homocysteine Levels, Haemostatic Risk Factors and Restenosis after Carotid Thrombendarterectomy
E Laxdal, GE Eide, SR Amundsen, EB Dregelid, G Pedersen, T Jonung, S Aune
European Journal of Vascular and Endovascular Surgery 2004
Fatty acids and homocysteine levels in patients with recurrent depression: an explorative pilot study
J Assies, A Lok, CL Bockting, GJ Weverling, R Lieverse, I Visser, NG Abeling, M Duran, AH Schene
Prostaglandins, Leukotrienes and Essential Fatty Acids 2004
Risk factors for heart failure
S Kenchaiah, J Narula, RS Vasan
Medical Clinics of North America 2004
Determinants of F2-isoprostane biosynthesis and inhibition in man
G Davı̀, A Falco, C Patrono
Chemistry and Physics of Lipids 2004
Ratios of homocysteine and nitrite to high-density lipoprotein in coronary artery patients with the different degree of stenosis
L Afrasyap, G Öztürk
Vascular Pharmacology 2004
Endothelial cell adhesion molecules in healthy adults during acute hyperhomocysteinemia and mild hypertriglyceridemia
MA Mansoor, I Seljeflot, H Arnesen, A Knudsen, CJ Bates, G Mishra, TW Larsen
Clinical Biochemistry 2004
Hypoxia upregulates the expression of the NDRG1 gene leading to its overexpression in various human cancers
H Cangul
BMC genetics 2004
Annotation and cross-indexing of array elements on multiple platforms
WB Mattes
Environmental Health Perspectives 2004
The effects of age and hyperhomocysteinemia on the redox forms of plasma thiols
DD Giuseppe, S Frosali, R Priora, FC di Simplicio, G Buonocore, C Cellesi, PL Capecchi, FL Pasini, PE Lazzerini, H Jakubowski, PD Simplicio
Journal of Laboratory and Clinical Medicine 2004
Relation of homocysteine and C-reactive protein to urinary albumin loss
N Seshadri, AW Messerli, N Acharya, GL Pearce, DW Jacobsen, MA Pohl, K Robinson, DL Sprecher
The American Journal of Cardiology 2004
Homocisteína en el paciente con diabetes mellitus
D Luis, N Fernández, R Aller
Medicina Clínica 2004
Hyperhomocysteinemia, endoplasmic reticulum stress, and alcoholic liver injury
C Ji, N Kaplowitz
World journal of gastroenterology : WJG 2004
Association between serum homocysteine and markers of impaired kidney function in adults in the United States
ME Francis, PW Eggers, TH Hostetter, JP Briggs
Kidney International 2004
The sigma receptor ligand (+)-pentazocine prevents apoptotic retinal ganglion cell death induced in vitro by homocysteine and glutamate
PM Martin, MS Ola, N Agarwal, V Ganapathy, SB Smith
Brain research. Molecular brain research 2004
Thiol status and antioxidant capacity in women with a history of severe pre-eclampsia
MT Raijmakers, EM Roes, PL Zusterzeel, EA Steegers, WH Peters
BJOG: An International Journal of Obstetrics and Gynaecology 2004
Effects of homocysteine on apoptosis-related proteins and anti-oxidant systems in isolated human lymphocytes
A Mangiagalli, A Samuele, MT Armentero, E Bazzini, G Nappi, F Blandini
European Journal of Biochemistry 2004
C677T polymorphism of the methylenetetrahydrofolate reductase gene is a risk factor of adverse events after coronary revascularization
N Botto, MG Andreassi, A Rizza, S Berti, S Bevilacqua, C Federici, C Palmieri, M Glauber, A Biagini
International Journal of Cardiology 2004
Elevated plasma homocysteine levels in gestational diabetes mellitus
E Tarim, T Bagis, E Kilicdag, S Erkanli, E Aslan, N Sezgin, E Kuscu
Acta Obstetricia et Gynecologica Scandinavica 2004
Ndrg1-deficient mice exhibit a progressive demyelinating disorder of peripheral nerves
T Okuda, Y Higashi, K Kokame, C Tanaka, H Kondoh, T Miyata
Molecular and cellular biology 2004
A role for homocysteine increase in haemolysis of megaloblastic anaemias due to vitamin B12 and folate deficiency: results from an in vitro experience
P Ventura, R Panini, S Tremosini, G Salvioli
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2004
Correlation of N-myc downstream-regulated gene 1 overexpression with progressive growth of colorectal neoplasm
Zhen Wang, Fang Wang, Wei-Qi Wang, Qian Gao, Wan-Li Wei, Yun Yang, Guo-Ying Wang
World journal of gastroenterology : WJG 2004
Acute negative inotropic effects of homocysteine are mediated via the endothelium
RH Kennedy, R Owings, N Shekhawat, J Joseph
American journal of physiology. Heart and circulatory physiology 2004
Design and statistical issues in the homocysteinemia in kidney and end stage renal disease (HOST) study
RL Jamison, P Hartigan, JM Gaziano, SP Fortmann, DS Goldfarb, JA Haroldson, J Kaufman, P Lavori, KS McCully, K Robinson
Clinical trials (London, England) 2004
Evidence for a protective (synergistic?) effect of B-vitamins and omega-3 fatty acids on cardiovascular diseases
A Bree, LI Mennen, S Hercberg, P Galan
European Journal of Clinical Nutrition 2004
Treatment of coronary heart disease with folic acid: is there a future?
SJ Moat, SN Doshi, D Lang, IF McDowell, MJ Lewis, J Goodfellow
American journal of physiology. Heart and circulatory physiology 2004
Opposite effect of methionine-supplemented diet, a model of hyperhomocysteinemia, on plasma and liver antioxidant status in normotensive and spontaneously hypertensive rats
S Robin, C Courderot-Masuyer, L Nicod, A Jacqueson, L Richert, A Berthelot
The Journal of Nutritional Biochemistry 2004
Clinical value of homocysteinemia (a review of literature)
YI Baranova, OO Bolshakova
2004
Chinese Yam ( Dioscorea alata cv. Tainung No. 2) Feeding Exhibited Antioxidative Effects in Hyperhomocysteinemia Rats
SJ Chang, YC Lee, SY Liu, TW Chang
Journal of Agricultural and Food Chemistry 2004
Biologically Important Thiols in Various Vegetables and Fruits
O Demirkol, C Adams, N Ercal
Journal of Agricultural and Food Chemistry 2004
Homocysteine and atherothrombosis: Diagnosis and treatment
DE Handy, J Loscalzo
Current Atherosclerosis Reports 2003
Nutrition and Heart Disease
A R.P.Walker
Nutrition and Heart Disease 2003
Treatment of hyperhomocysteinemia in pediatric heart transplant recipients
F Parisi, H Danesi, VD Ciommo, F Fina, G Giannone, F Colistro, RM di Donato, G Catena
The Journal of Heart and Lung Transplantation 2003
Mechanisms of nitrate tolerance: potential roles of folate
FI Bellisarii, S Gallina, M Zimarino, RD Caterina
European Journal of Clinical Investigation 2003
Effects of vitamin supplementation and hyperhomocysteinemia on atherosclerosis in apoE-deficient mice
J Zhou, J Møller, M Ritskes-Hoitinga, ML Larsen, RC Austin, E Falk
Atherosclerosis 2003
Stimulatory Effect of Homocysteine on Interleukin-8 Expression in Human Endothelial Cells
J Geisel, V Jödden, R Obeid, JP Knapp, M Bodis, W Herrmann
Clinical Chemistry and Laboratory Medicine 2003
Coronary atherosclerosis and somatic mutations: an overview of the contributive factors for oxidative DNA damage
MG Andreassi
Mutation Research/Reviews in Mutation Research 2003
Interactions of Homocysteine, Nitric Oxide, Folate and Radicals in the Progressively Damaged Endothelium
O Stanger, M Weger
Clinical Chemistry and Laboratory Medicine 2003
Effects of 3-deazaadenosine on homocysteine and atherosclerosis in apolipoprotein E-deficient mice
AC Langheinrich, RC Braun-Dullaeus, G Walker, I Jeide, R Schilling, K Tammoscheit, T Dreyer, L Fink, RM Bohle, W Haberbosch
Atherosclerosis 2003
Effects of Prostaglandin E1, Melatonin, and Oxytetracycline on Lipid Peroxidation, Antioxidant Defense System, Paraoxonase (PON1) Activities, and Homocysteine Levels in an Animal Model of Spinal Cord Injury
C Topsakal, N Kilic, F Ozveren, I Akdemir, M Kaplan, M Tiftikci, F Gursu
Spine 2003
Meta-analysis of plasma homocysteine, serum folate, serum vitamin B12, and thermolabile MTHFR genotype as risk factors for retinal vascular occlusive disease
MT Cahill, SS Stinnett, S Fekrat
American Journal of Ophthalmology 2003
Folate Improves Endothelial Function in Patients with Coronary Heart Disease
S Doshi, I McDowell, S Moat, M Lewis, J Goodfellow
Clinical Chemistry and Laboratory Medicine 2003
Endothelial nitric oxide synthase gene polymorphism, homocysteine, cholesterol and vascular endothelial function
W Bilsborough, DJ Green, CD Mamotte, FM van Bockxmeer, GJ O'Driscoll, RR Taylor
Atherosclerosis 2003
Intracellular Redox Status Modulates Monocyte Chemoattractant Protein-1 Expression Stimulated by Homocysteine in Endothelial Cells
HS Zhang, EH Cao, JF Qin
Journal of Cardiovascular Pharmacology 2003
Hyperhomocysteinemia and Cardiovascular Disease: New Mechanisms Beyond Atherosclerosis
J Joseph, L Joseph
Metabolic Syndrome and Related Disorders 2003
Obstructive sleep apnoea syndrome – an oxidative stress disorder
L Lavie
Sleep Medicine Reviews 2003
Folic acid says NO to vascular diseases
UN Das
Nutrition 2003
Hyperhomocysteinemia in heart transplantation: from bench to bedside
SG Miriuka, DH Delgado, DE Cole, V Rao, HJ Ross
The Journal of Heart and Lung Transplantation 2003
Hyperhomocysteinemia and its role in the development of atherosclerosis
AB de Koning, GH Werstuck, J Zhou, RC Austin
Clinical Biochemistry 2003
Protein-bound uremic retention solutes
P Brunet, L Dou, C Cerini, Y Berland
Advances in renal replacement therapy 2003
A 2-step strategy to reduce the need for methionine-loading tests to diagnose hyperhomocysteinemia
MF van de Laak, DE Grobbee, R der Griend, HW de Valk, A Algra, JD Banga, Y der Graaf
Journal of Laboratory and Clinical Medicine 2003
Hyperhomocysteinemia, endothelial dysfunction, and cardiovascular risk: the potential role of ADMA
SR Lentz, RN Rodionov, S Dayal
Atherosclerosis Supplements 2003
The Impact of Hyperhomocysteinemia as a Cardiovascular Risk Factor in the Prediction of Coronary Heart Disease
J Geisel, B Hennen, U Hübner, JP Knapp, W Herrmann
Clinical chemistry and laboratory medicine : CCLM / FESCC 2003
Hyperhomocysteinemia and Oxidative Stress During Dialysis Treatment
PG Chiarello, MT Vannucchi, H Vannucchi
Renal Failure 2003
Effects of low-dose 17-β-estradiol plus norethisterone acetate and tibolone on fasting plasma homocysteine levels in postmenopausal women
B Kaleli, B Yildirim, S Demir, E Alatas
Acta Obstetricia et Gynecologica Scandinavica 2003
Antiphospholipid antibodies as a risk factor for atherosclerotic events in renal transplant recipients
D Ducloux, E Bourrinet, G Motte, JM Chalopin
Kidney International 2003
Possible mechanisms of homocysteine toxicity
AF Perna, D Ingrosso, C Lombardi, F Acanfora, E Satta, CM Cesare, E Violetti, MM Romano, NG de Santo
Kidney International 2003
Cellular distribution of NDRG1 protein in the rat kidney and brain during normal postnatal development
Y Wakisaka, A Furuta, K Masuda, W Morikawa, M Kuwano, T Iwaki
Journal of Histochemistry & Cytochemistry 2003
Hyperhomocysteinemia leads to pathological ventricular hypertrophy in normotensive rats
J Joseph, L Joseph, NS Shekhawat, S Devi, J Wang, RB Melchert, M Hauer-Jensen, RH Kennedy
American journal of physiology. Heart and circulatory physiology 2003
Oxidative stress-induced dysregulation of arteriolar wall shear stress and blood pressure in hyperhomocysteinemia is prevented by chronic vitamin C treatment
Z Bagi, C Csekö, E Tóth, A Koller
American journal of physiology. Heart and circulatory physiology 2003
Plasma thiols and their determinants in phenylketonuria
C Colomé, R Artuch, C Sierra, N Brandi, N Lambruschini, J Campistol, MA Vilaseca
European Journal of Clinical Nutrition 2003
Genetic polymorphisms in folate and homocysteine metabolism as risk factors for DNA damage
N Botto, MG Andreassi, S Manfredi, S Masetti, F Cocci, MG Colombo, S Storti, A Rizza, A Biagini
European Journal of Human Genetics 2003
Homocysteine Induces Trophoblast Cell Death with Apoptotic Features
ND Simone
Biology of reproduction 2003
Determinants of hyperhomocysteinemia in patients with chronic liver disease and after orthotopic liver transplantation
A Bosy-Westphal, M Ruschmeyer, N Czech, G Oehler, H Hinrichsen, M Plauth, E Lotterer, W Fleig, MJ Müller
The American journal of clinical nutrition 2003
Review: Homocysteine, endothelial dysfunction and oxidative stress in type 1 diabetes mellitus
F Wotherspoon, DW Laight, KM Shaw, MH Cummings
The British Journal of Diabetes & Vascular Disease 2003
Infections and the Cardiovascular System: New Perspectives
IW Fong
2003
Extracellular superoxide dismutase in biology and medicine
CL Fattman, LM Schaefer, TD Oury
Free radical biology & medicine 2003
Cardiovascular Risk in Type 2 Diabetes Mellitus
N Hâncu
2003
Hyperhomocysteinemia Induces Renal Hemodynamic Dysfunction: Is Nitric Oxide Involved?
PA Fischer, GN Dominguez, LA Cuniberti, V Martinez, JP Werba, AJ Ramirez, LD Masnatta
Journal of the American Society of Nephrology : JASN 2003
l-Homocysteine Sulfinic Acid and Other Acidic Homocysteine Derivatives Are Potent and Selective Metabotropic Glutamate Receptor Agonists
Q Shi, JE Savage, SJ Hufeisen, L Rauser, E Grajkowska, P Ernsberger, JT Wroblewski, JH Nadeau, BL Roth
The Journal of pharmacology and experimental therapeutics 2003
Antioxidant improves smooth muscle sarco/endoplasmic reticulum Ca(2+)-ATPase function and lowers tyrosine nitration in hypercholesterolemia and improves nitric oxide-induced relaxation
T Adachi, R Matsui, S Xu, M Kirber, HL Lazar, VS Sharov, C Schöneich, RA Cohen
Circulation research 2002
Effect of prolonged incubation with copper on endothelium-dependent relaxation in rat isolated aorta
A Chiarugi, GM Pitari, R Costa, M Ferrante, L Villari, M Amico-Roxas, T Godfraind, A Bianchi, S Salomone
British Journal of Pharmacology 2002
Endothelial Dysfunction in Children with Type 1 Diabetes Mellitus
Μ Pomilio, Α Mohn, A Verrotti, F Chiarelli
Journal of Pediatric Endocrinology and Metabolism 2002
Sustained increases of plasma homocysteine, copper, and serum ceruloplasmin after coronary artery bypass grafting
JY Jeremy, N Shukla, GD Angelini, A Day, IY Wan, SP Talpahewa, R Ascione
The Annals of Thoracic Surgery 2002
17-β Estradiol Preserves Endothelial Cell Viability in an In Vitro Model of Homocysteine-Induced Oxidative Stress
KR Dimitrova, KW DeGroot, JP Suyderhoud, EA Pirovic, TJ Munro, J Wieneke, AK Myers, YD Kim
Journal of Cardiovascular Pharmacology 2002
Intraperitoneal infusion of homocysteine increases intimal hyperplasia in balloon-injured rat carotid arteries
C Chen, SM Surowiec, AH Morsy, M Ma
Atherosclerosis 2002
Homocysteine in Myointimal Hyperplasia
M Hansrani, JI Gillespie, G Stansby
European Journal of Vascular and Endovascular Surgery 2002
Plasma aminothiol oxidation in chronic hemodialysis patients
J Himmelfarb, E McMenamin, E McMonagle
Kidney International 2002
Upregulation of smooth muscle cell collagen production by homocysteine—insight into the pathogenesis of homocystinuria
AK Majors, S Sengupta, DW Jacobsen, RE Pyeritz
Molecular Genetics and Metabolism 2002
Fenofibrate induces a selective increase of protein-bound homocysteine in rodents: a PPARα-mediated effect
C Legendre, E Caussé, E Chaput, R Salvayre, T Pineau, AD Edgar
Biochemical and Biophysical Research Communications 2002
Effects of homocysteine thiol group on fibrin networks: another possible mechanism of harm
AM Lauricella, IL Quintana, LC Kordich
Thrombosis Research 2002
Effects of Certain Micronutrients and Melatonin on Plasma Lipid, Lipid Peroxidation, and Homocysteine Levels in Rats
G Baydas, O Yilmaz, S Celik, A Yasar, M Gursu
Archives of Medical Research 2002
Insulin Increases Homocysteine Levels in a Dose-Dependent Manner in Diabetic Rats
MF Gursu, G Baydas, G Cikim, H Canatan
Archives of Medical Research 2002
Homocysteine levels and decline in physical function: MacArthur studies of successful aging
DM Kado, A Bucur, J Selhub, JW Rowe, T Seeman
The American Journal of Medicine 2002
Usefulness of plasma vitamin B6, B12, folate, homocysteine, and creatinine in predicting outcomes in heart transplant recipients
M Nahlawi, N Seshadri, N Boparai, A Naso, DW Jacobsen, P McCarthy, J Young, K Robinson
The American Journal of Cardiology 2002
Endothelial dysfunction and atherothrombosis in mild hyperhomocysteinemia
N Weiss, C Keller, U Hoffmann, J Loscalzo
Vascular medicine (London, England) 2002
Association of hyperhomocysteinemia with plasma sulfate and urine sulfate excretion in patients with progressive renal disease
T Nakanishi, Y Otaki, Y Hasuike, M Nanami, R Itahana, K Miyagawa, H Nishikage, M Izumi, Y Takamitsu
American Journal of Kidney Diseases 2002
Vitamin Supplementation Normalizes Total Plasma Homocysteine Concentration but Not Plasma Homocysteine Redox Status in Patients with Acute Coronary Syndromes and Hyperhomocysteinemia
A Andersson, T Jonasson, H Öhlin, A Lindgren, B Hultberg
Clinical chemistry and laboratory medicine : CCLM / FESCC 2002
Inhibitory Effect of Melatonin on Homocysteine-Induced Lipid Peroxidation in Rat Brain Homogenates
C Osuna, RJ Reiter, JJ Garcia, M Karbownik, DX Tan, JR Calvo, LC Manchester
Pharmacology and Toxicology 2002
Treatment of Hyperhomocysteinemia with Folic Acid: Effects on Homocysteine Levels, Coagulation Status, and Oxidative Stress Markers:
O Mayer, J Filipovský, M Hromádka, V Svobodová, J Racek, O Mayer, P Stehlík, L Trefil, M Zárybnická
Journal of Cardiovascular Pharmacology 2002
Homocysteine, white matter hyperintensities, and cognition in healthy elderly people: Homocysteine and Cognition
C Dufouil, A Alpérovitch, V Ducros, C Tzourio
Annals of Neurology 2002
Hyperhomocysteinaemia and cardiovascular risk in female ovariectomized rats: role of folic acid and hormone replacement therapy
Sahar E el-Swefy, Sousou I Ali, Mervat E Asker, Hoda E Mohamed
The Journal of pharmacy and pharmacology 2002
Homocysteine and occlusive arterial disease
H O'Grady, C Kelly, D Bouchier-Hayes, A Leahy
The British journal of surgery 2002
Elevated plasma total homocysteine levels in hyperinsulinemic obese subjects
V Sánchez-Margalet, M Valle, FJ Ruz, F Gascón, J Mateo, R Goberna
The Journal of Nutritional Biochemistry 2002
N-Acetylcysteine, Vitamin C and Vitamin E Diminish Homocysteine Thiolactone-Induced Apoptosis in Human Promyeloid HL-60 Cells
RF Huang, SM Huang, BS Lin, CY Hung, HT Lu
The Journal of nutrition 2002
Hyperhomocysteinemia Due to Short-Term Folate Deprivation Is Related to Electron Microscopic Changes in the Rat Brain
J Kim, H Lee, N Chang
The Journal of nutrition 2002
Homocysteine, B vitamin status, and cognitive function in the elderly
SJ Duthie, LJ Whalley, AR Collins, S Leaper, K Berger, IJ Deary
The American journal of clinical nutrition 2002
Cellular Redox State and Endothelial Dysfunction in Mildly Hyperhomocysteinemic Cystathionine β-Synthase–Deficient Mice
N Weiss, S Heydrick, YY Zhang, C Bierl, A Cap, J Loscalzo
Arteriosclerosis, thrombosis, and vascular biology 2002
Deficiency of Glutathione Peroxidase-1 Sensitizes Hyperhomocysteinemic Mice to Endothelial Dysfunction
S Dayal, KL Brown, CJ Weydert, LW Oberley, E Arning, T Bottiglieri, FM Faraci, SR Lentz
Arteriosclerosis, thrombosis, and vascular biology 2002
Does Oral Folic Acid Lower Total Homocysteine Levels and Improve Endothelial Function in Children With Chronic Renal Failure?
K Bennett-Richards, M Kattenhorn, A Donald, G Oakley, Z Varghese, L Rees, JE Deanfield
Circulation 2002
Vascular Responses in Male and Female Hypertensive Rats With Hyperhomocysteinemia
CH Yen, YT Lau
Hypertension 2002
Effect of Dexrazoxane on Homocysteine-Induced Endothelial Dysfunction in Normal Subjects
H Zheng, C Dimayuga, A Hudaihed, SD Katz
Arteriosclerosis, thrombosis, and vascular biology 2002
Effects of pinealectomy on the levels and the circadian rhythm of plasma homocysteine in rats: Pinealectomy and homocysteine levels
G Baydas, MF Gursu, G Cikim, S Canpolat, A Yasar, H Canatan, H Kelestimur
Journal of Pineal Research 2002
Effects of Folate Treatment and Homocysteine Lowering on Resistance Vessel Reactivity in Atherosclerotic Subjects
O Stanger, HJ Semmelrock, W Wonisch, U Bös, E Pabst, TC Wascher
The Journal of pharmacology and experimental therapeutics 2002
Hyperhomocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model
Marion A. Hofmann, Evanthia Lalla, Yan Lu, Michelle Ryu Gleason, Bonnie M. Wolf, Nozomu Tanji, Luis A. Ferran, Jr., Brigite Kohl, Vijay Rao, Walter Kisiel, David M. Stern, Ann Marie Schmidt
Journal of Clinical Investigation 2001
Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways
Geoff H. Werstuck, Steven R. Lentz, Sanjana Dayal, Gazi S. Hossain, Sudesh K. Sood, Yuan Y. Shi, Ji Zhou, Nobuyo Maeda, Skaidrite K. Krisans, M. Rene Malinow, Richard C. Austin
Journal of Clinical Investigation 2001
Homocysteine: A sulph'rous fire
Katherine Hajjar
Journal of Clinical Investigation 2001
Hyperhomocysteinemia and function of the endoplasmic reticulum
David Ron
Journal of Clinical Investigation 2001
Overexpression of cellular glutathione peroxidase rescues homocyst(e)ine-induced endothelial dysfunction
N Weiss, YY Zhang, S Heydrick, C Bierl, J Loscalzo
Proceedings of the National Academy of Sciences 2001
Homocysteine and atherothrombosis
E Falk, J Zhou, J Møller
Lipids 2001
Impaired Homocysteine Metabolism and Atherothrombotic Disease
P Durand, M Prost, N Loreau, S Lussier-Cacan, D Blache
Laboratory Investigation 2001
Vitamin C Prevents Radiation-Induced Endothelium-Dependent Vasomotor Dysfunction And De-Endothelialization By Inhibiting Oxidative Damage In The Rat
YK On, HS Kim, SY Kim, IH Chae, BH Oh, MM Lee, YB Park, YS Choi, MH Chung
Clinical and Experimental Pharmacology and Physiology 2001
Differences between cysteine and homocysteine in the induction of deoxyribose degradation and DNA damage
P Muñiz, P Sáez, A Iradi, J Viña, MR Oliva, GT Sáez
Free radical biology & medicine 2001
Therapeutic potential of dietary phase 2 enzyme inducers in ameliorating diseases that have an underlying inflammatory component
BH Juurlink
Canadian Journal of Physiology and Pharmacology 2001
The effect on endothelial function of vitamin C during methionine induced hyperhomocysteinaemia
CG Hanratty, LT McGrath, DF McAuley, IS Young, DG Johnston
BMC Cardiovascular Disorders 2001
Hyperhomocyst(e)inaemia, but not MTHFR C677T mutation, as a risk factor for non-arteritic ischaemic optic neuropathy
M Weger, O Stanger, H Deutschmann, M Simon, W Renner, O Schmut, J Semmelrock, A Haas
The British journal of ophthalmology 2001
Homocysteine stimulates the expression of monocyte chemoattractant protein-1 receptor (CCR2) in human monocytes: possible involvement of oxygen free radicals
G Wang, K O
Biochemical Journal 2001
Redox-Sensitive Regulation of LOX-1 Gene Expression in Vascular Endothelium
M Nagase, K Ando, T Nagase, S Kaname, T Sawamura, T Fujita
Biochemical and Biophysical Research Communications 2001
Melatonin Counteracts Potentiation by Homocysteine of KCl-Induced Vasoconstriction in Human Umbilical Artery: Relation to Calcium Influx
Y Okatani, A Wakatsuki, RJ Reiter
Biochemical and Biophysical Research Communications 2001
Hyperhomocysteinemia and Changed Plasma Thiol Redox Status in Chronic Obstructive Pulmonary Disease
A Andersson, J Ankerst, A Lindgren, K Larsson, B Hultberg
Clinical Chemistry and Laboratory Medicine 2001
Homocysteine attenuates endothelial haem oxygenase-1 induction by nitric oxide (NO) and hypoxia
P Sawle, R Foresti, CJ Green, R Motterlini
FEBS Letters 2001
Homocysteine: a novel risk factor in vascular disease
J Auer, R Berent, B Eber
Coronary Health Care 2001
Homocysteine inhibits TNF-alpha-induced endothelial adhesion molecule expression and monocyte adhesion via nuclear factor-kappaB dependent pathway
V Stangl, C Günther, A Jarrin, P Bramlage, M Moobed, A Staudt, G Baumann, K Stangl, SB Felix
Biochemical and Biophysical Research Communications 2001
Folate improves endothelial function in coronary artery disease: an effect mediated by reduction of intracellular superoxide?
SN Doshi, IF McDowell, SJ Moat, D Lang, RG Newcombe, MB Kredan, MJ Lewis, J Goodfellow
Arteriosclerosis, thrombosis, and vascular biology 2001
Oxidative stress and platelet activation in homozygous homocystinuria
G Davì, GD Minno, A Coppola, G Andria, AM Cerbone, P Madonna, A Tufano, A Falco, P Marchesani, G Ciabattoni, C Patrono
Circulation 2001
Acute Methionine Loading Does not Alter Arterial Stiffness in Humans:
IB Wilkinson, IL Megson, H MacCallum, DF Rooijmans, SM Johnson, JL Boyd, JR Cockcroft, DJ Webb
Journal of Cardiovascular Pharmacology 2001
Homocysteine in breast cyst fluid
J Tallova, J Tomandl, M Bicikova, M Simickova
European Journal of Clinical Investigation 2001
Hyperhomocysteinaemia in Patients with Peripheral Arterial Occlusive Disease
S Jong
Clinical chemistry and laboratory medicine : CCLM / FESCC 2001
Hyperhomocysteinemia and transplant coronary artery disease in cardiac transplant recipients
SE Miner, DE Cole, J Evrovski, A Verma, PA Daly, HJ Ross
Clinical Transplantation 2001
Determination of biological thiols by high-performance liquid chromatography following derivatization by ThioGlo maleimide reagents
N Ercal, P Yang, N Aykin
Journal of Chromatography B Biomedical Sciences and Applications 2001
Ras1 interacts with multiple new signaling and cytoskeletal loci in Drosophila eggshell patterning and morphogenesis
JD Schnorr, R Holdcraft, B Chevalier, CA Berg
Genetics 2001
Heart disease and vascular risk factors in the cognitively impaired elderly: Implications for Alzheimer’s dementia
MC Polidori, M Marvardi, A Cherubini, U Senin, P Mecocci
Aging clinical and experimental research 2001
Pathogenesis of Hyperhomocysteinemia—New Insights
A Khajuria, DS Houston
Hematology 2001
Homocyst(e)ine, oxidative stress, and endothelium function in uremic patients
ZA Massy, I Ceballos, B Chadefaux-Vekemens, T Nguyen-Khoa, B Descamps-Latscha, TB Drüeke, P Jungers
Kidney International 2001
Inflammation, not hyperhomocysteinemia, is related to oxidative stress and hemostatic and endothelial dysfunction in uremia
D Mezzano, EO Pais, E Aranda, O Panes, P Downey, M Ortiz, R Tagle, F González, T Quiroga, MS Caceres, F Leighton, J Pereira
Kidney International 2001
Plasma Homocysteine Levels in Obstructive Sleep Apnea
L Lavie, A Perelman, P Lavie
Chest 2001
Is homocysteine a pro-oxidant?
B Zappacosta, A Mordente, S Persichilli, A Minucci, P Carlino, GE Martorana, B Giardina, P Sole
Free Radical Research 2001
Do Different Dialytic Techniques Have Different Atherosclerotic and Antioxidant Activities?:
S Biasioli, R Schiavon, L Petrosino, L Cavallini, ED Fanti, A Zambello, D Borin, L Targa
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2001
Homocysteine—a novel risk factor for vascular disease
JC Chambers, MD Seddon, S Shah, JS Kooner
Journal of the Royal Society of Medicine 2001
Folate Depletion and Elevated Plasma Homocysteine Promote Oxidative Stress in Rat Livers
RF Huang, YC Hsu, HL Lin, FL Yang
The Journal of nutrition 2001
Hyperhomocysteinemia and inflammatory bowel disease: prevalence and predictors in a cross-sectional study
J Romagnuolo, RN Fedorak, VC Dias, F Bamforth, M Teltscher
The American Journal of Gastroenterology 2001
Endothelial Dysfunction and Elevation of S -Adenosylhomocysteine in Cystathionine β-Synthase–Deficient Mice
S Dayal, T Bottiglieri, E Arning, N Maeda, MR Malinow, CD Sigmund, DD Heistad, FM Faraci, SR Lentz
Circulation research 2001
Does Homocysteine Promote Atherosclerosis?
SR Lentz
Arteriosclerosis, thrombosis, and vascular biology 2001
Supplementation of Atherogenic Diet With B Vitamins Does Not Prevent Atherosclerosis or Vascular Dysfunction in Monkeys
SR Lentz, DJ Piegors, MR Malinow, DD Heistad
Circulation 2001
Taurine Prevents the Decrease in Expression and Secretion of Extracellular Superoxide Dismutase Induced by Homocysteine: Amelioration of Homocysteine-Induced Endoplasmic Reticulum Stress by Taurine
H Nonaka, T Tsujino, Y Watari, N Emoto, M Yokoyama
Circulation 2001
Folate and Nitrate-Induced Endothelial Dysfunction: A Simple Treatment for a Complex Pathobiology
J Loscalzo
Circulation 2001
Relation of a Common Methylenetetrahydrofolate Reductase Mutation and Plasma Homocysteine With Intimal Hyperplasia After Coronary Stenting
T Kosokabe, K Okumura, T Sone, J Kondo, H Tsuboi, H Mukawa, T Tomida, T Suzuki, H Kamiya, H Matsui, T Hayakawa
Circulation 2001
Hyperhomocysteinemia and Oxidative Stress in Ischemic Stroke
MC Polidori, A Cherubini, U Senin, P Mecocci
Stroke; a journal of cerebral circulation 2001
Inflammation and Stroke
GZ Feuerstein
2001
Homocysteine and lipid peroxidation in haemodialysis: role of folinic acid and vitamin E
B Bayés, M Cruz, J Bonal, J Juncà, R Romero
Nephrology Dialysis Transplantation 2001
Endothelial dysfunction in a murine model of mild hyperhomocyst(e)inemia
Robert T. Eberhardt, Marc A. Forgione, Andre Cap, Jane A. Leopold, M. Audrey Rudd, Maria Trolliet, Stanley Heydrick, Rachel Stark, Elizabeth S. Klings, Nicanor I. Moldovan, Mohammed Yaghoubi, Pascal J. Goldschmidt-Clermont, Harrison W. Farber, Richard Co
Journal of Clinical Investigation 2000
Elevated plasma homocysteine concentrations after pediatric heart transplantations
F Parisi, S Kost-Byerly, I Saponara, R Donato, G Liso
Transplant International 2000
The effect of elevated homocysteine levels on adrenergic vasoconstriction of human resistance arteries: The role of the endothelium and reactive oxygen species
MJ Cipolla, WK Williamson, ML Nehler, LM Taylor, JM Porter
Journal of Vascular Surgery 2000
Nutritional aspects and possible pathological mechanisms of hyperhomocysteinaemia: an independent risk factor for vascular disease
MC McKinley
Proceedings of the Nutrition Society 2000
Homocysteine stimulates nuclear factor kappaB activity and monocyte chemoattractant protein-1 expression in vascular smooth-muscle cells: a possible role for protein kinase C
G Wang, YL Siow, K O
Biochemical Journal 2000
Peroxidation indices and total antioxidant capacity in plasma during hyperhomocysteinemia induced by methionine oral loading
P Ventura, R Panini, C Verlato, G Scarpetta, G Salvioli
Metabolism 2000
Protective Effect of Melatonin against Homocysteine-Induced Vasoconstriction of Human Umbilical Artery
Y Okatani, A Wakatsuki, RJ Reiter
Biochemical and Biophysical Research Communications 2000
Effect of folic acid and antioxidant vitamins on endothelial dysfunction in patients with coronary artery disease
LM Title, PM Cummings, K Giddens, JJ Genest, BA Nassar
Journal of the American College of Cardiology 2000
Effects of supplementation with folic acid and antioxidant vitamins on homocysteine levels and LDL oxidation in coronary patients
D Bunout, A Garrido, M Suazo, R Kauffman, P Venegas, P la Maza, M Petermann, S Hirsch
Nutrition 2000
Low serum folate but normal homocysteine levels in patients with atherosclerotic vascular disease and matched healthy controls
D Bunout, M Petermann, S Hirsch, P la Maza, M Suazo, G Barrera, R Kauffman
Nutrition 2000
Homocysteine-induced changes in mRNA levels of genes coding for cytoplasmic- and endoplasmic reticulum-resident stress proteins in neuronal cell cultures
PA Outinen, SK Sood, PC Liaw, KD Sarge, N Maeda, J Hirsh, J Ribau, TJ Podor, JI Weitz, RC Austin
Molecular Brain Research 2000
ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response
H Yoshida, T Okada, K Haze, H Yanagi, T Yura, M Negishi, K Mori
Molecular and cellular biology 2000
Errores congénitos del metabolismo: ¿causa de estrés oxidativo?
C Colomé, C Sierra, MA Vilaseca
Medicina Clínica 2000
Hyperhomocysteinemia impairs angiogenesis in response to hindlimb ischemia
J Duan, T Murohara, H Ikeda, K Sasaki, S Shintani, T Akita, T Shimada, T Imaizumi
Arteriosclerosis, thrombosis, and vascular biology 2000
Relationship between homocysteine and superoxide dismutase in homocystinuria: possible relevance to cardiovascular risk
DE Wilcken, XL Wang, T Adachi, H Hara, N Duarte, K Green, B Wilcken
Arteriosclerosis, thrombosis, and vascular biology 2000
N-myc downstream-regulated gene 1 is mutated in hereditary motor and sensory neuropathy-Lom
L Kalaydjieva, D Gresham, R Gooding, L Heather, F Baas, R Jonge, K Blechschmidt, D Angelicheva, D Chandler, P Worsley, A Rosenthal, RH King, PK Thomas
The American Journal of Human Genetics 2000
Role of Cellulosic and Noncellulosic Membranes in Hyperhomocysteinemia and Oxidative Stress:
S Biasioli, R Schiavon, L Petrosino, L Cavallini, G Cavalcanti, ED Fanti, A Zambello, D Borin
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2000
Methylene tetrahydrofolate reductase (MTHFR) and nitric oxide synthase (ecNOS) genes and risks of peripheral arterial disease and coronary heart disease: Edinburgh artery study
FG Fowkes, AJ Lee, CM Hau, A Cooke, JM Connor, GD Lowe
Atherosclerosis 2000
A tale of two homocysteines—and two hemodialysis units
LJ Hoffer, I Bank, P Hongsprabhas, I Shrier, F Saboohi, M Davidman, DD Bercovitch, PE Barré
Metabolism 2000
Severe retinopathy in type 1 diabetic patients is not related to the level of plasma homocysteine
E Agardh, B Hultberg, CD Agardh
Scandinavian Journal of Clinical & Laboratory Investigation 2000
Elevated plasma homocysteine elicits an increase in antioxidant enzyme activity
SJ Moat, JR Bonham, RA Cragg, HJ Powers
Free Radical Research 2000
Homocysteine as a Risk Factor for Atherosclerosis
ME Temple, AB Luzier, DJ Kazierad
The Annals of pharmacotherapy 2000
Homocysteine Inhibits Inactivation of Factor Va by Activated Protein C
A Undas, EB Williams, S Butenas, T Orfeo, KG Mann
The Journal of biological chemistry 2000
Folate dependence of hyperhomocysteinemia and vascular dysfunction in cystathionine β-synthase-deficient mice
SR Lentz, RA Erger, S Dayal, N Maeda, MR Malinow, DD Heistad, FM Faraci
American journal of physiology. Heart and circulatory physiology 2000
Effects of homocysteine on endothelial nitric oxide production
X Zhang, H Li, H Jin, Z Ebin, S Brodsky, MS Goligorsky
American journal of physiology. Renal physiology 2000
Oxidative Stress and Vascular Disease
JF Keaney
2000
Homocysteine and Vascular Disease
K Robinson
2000
High-dose folic acid supplementation in rats: effects on gestation and the methionine cycle
M Achón, E Alonso-Aperte, L Reyes, N Úbeda, G Varela-Moreiras
British Journal of Nutrition 2000
Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity
I I Kruman, C Culmsee, S L Chan, Y Kruman, Z Guo, L Penix, M P Mattson
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000
Occlusive Vascular Diseases in Oral Contraceptive Users: Epidemiology, Pathology and Mechanisms
IF Godsland, U Winkler, O Lidegaard, D Crook
Drugs 2000
HOMOCYSTEINE METABOLISM
J Selhub
Annual Review of Nutrition 1999
Total homocysteine and cardiovascular disease
O Nygard, SE Vollset, H Refsum, L Brattstrom, PM Ueland
Journal of Internal Medicine 1999
Homocysteine, a risk factor for cardiovascular disease
K Prasad
International Journal of Angiology 1999
Investigation of the inhibitory effects of homocysteine and copper on nitric oxide-mediated relaxation of rat isolated aorta
AM Emsley, JY Jeremy, GN Gomes, GD Angelini, F Plane
British Journal of Pharmacology 1999
Anti-oxidant therapy for the treatment of coronary artery disease
MJ Kendall, SL Nuttall
Expert Opinion on Investigational Drugs 1999
Homocysteine and atherosclerosis
GT Gerhard, PB Duell
Current Opinion in Lipidology 1999
Can lowering homocysteine levels reduce the incidence of stroke?
PK Sarkar, L Lambert
Journal of Clinical Pharmacy and Therapeutics 1999
Modulation of Angiotensin II Signaling for GATA4 Activation by Homocysteine
YJ Suzuki, SS Shi, JB Blumberg
Antioxidants & Redox Signaling 1999
Characterization of the adduct formed from the reaction between homocysteine thiolactone and low-density lipoprotein: antioxidant implications
E Ferguson, N Hogg, WE Antholine, J Joseph, RJ Singh, S Parthasarathy, B Kalyanaraman
Free radical biology & medicine 1999
Oxidant stress in the vasculature
M Maytin, J Leopold, J Loscalzo
Current Atherosclerosis Reports 1999
Homocysteine: cholesterol of the 90s?
LJ Langman, DE Cole
Clinica Chimica Acta 1999
EFFECT OF HOMOCYSTEINE ON THE PRODUCTION OF NITRIC OXIDE IN ENDOTHELIAL CELLS
KI Chow, FI Cheung, TE Lao, K O
Clinical and Experimental Pharmacology and Physiology 1999
Plasma Homocysteine As a Cardiovascular Risk Factor: Causal, Consequential, or of No Consequence?
R Meleady, I Graham
Nutrition Reviews 1999
Cellular adhesion molecules and atherogenesis
DT Price, J Loscalzo
The American Journal of Medicine 1999
Homocysteine provokes leukocyte–endothelium interaction by downregulation of nitric oxide
D Pruefer, R Scalia, AM Lefer
General Pharmacology: The Vascular System 1999
Effect of short-term vitamin (folic acid, vitamins B6 and B12) administration on endothelial dysfunction induced by post-Methionine load hyperhomocysteinemia
CL Chao, KL Chien, YT Lee
The American Journal of Cardiology 1999
Reduction of homocysteine levels in coronary artery disease by low-dose folic acid combined with vitamins B6 and B12
A Lobo, A Naso, K Arheart, WD Kruger, T Abou-Ghazala, F Alsous, M Nahlawi, A Gupta, A Moustapha, F Lente, DW Jacobsen, K Robinson
The American Journal of Cardiology 1999
Role of oxidant stress in endothelial dysfunction produced by experimental hyperhomocyst(e)inemia in humans
PM Kanani, CA Sinkey, RL Browning, M Allaman, HR Knapp, WG Haynes
Circulation 1999
Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response
TW Fawcett, JL Martindale, KZ Guyton, T Hai, NJ Holbrook
Biochemical Journal 1999
Demonstration of rapid onset vascular endothelial dysfunction after hyperhomocysteinemia: an effect reversible with vitamin C therapy
JC Chambers, A McGregor, J Jean-Marie, OA Obeid, JS Kooner
Circulation 1999
Electrophysiological effects of homocysteine in isolated rat right ventricular papillary muscles and left atria
P Pacher, Z Ungvari, V Kecskemeti
General Pharmacology: The Vascular System 1999
Homocysteine
LJ Langman, DE Cole
Critical Reviews in Clinical Laboratory Sciences 1999
Methylenetetrahydrofolate Reductase Polymorphism, Folate, and Susceptibility to Preeclampsia
RW Powers, LA Minish, DL Lykins, RB Ness, WR Crombleholme, JM Roberts
Journal of the Society for Gynecologic Investigation 1999
Coronary heart disease:
DL Ellsworth, P Sholinsky, C Jaquish, RR Fabsitz, TA Manolio
American Journal of Preventive Medicine 1999
Plasma Total Homocyst(e)ine May Not Be the Most Appropriate Index for Cardiovascular Disease Risk
EB Stamm, RD Reynolds
The Journal of nutrition 1999
Plasma Homocysteine Levels in Acute Coronary Syndromes
N TURGAN, B BOYDAK, S HABIF, S APAKKAN, D ÖZMEN, I MUTAF, O BAYINDIR
Japanese Heart Journal 1999
High Dietary Folate Supplementation Affects Gestational Development and Dietary Protein Utilization in Rats
M Achón, L Reyes, E Alonso-Aperte, N Úbeda, G Varela-Moreiras
The Journal of nutrition 1999
Dysfunction of Nitric Oxide Mediation in Isolated Rat Arterioles With Methionine Diet–Induced Hyperhomocysteinemia
Z Ungvari, P Pacher, K Rischák, L Szollár, A Koller
Arteriosclerosis, thrombosis, and vascular biology 1999
ATF3 and stress responses
T Hai, C D Wolfgang, D K Marsee, A E Allen, U Sivaprasad
Gene expression 1999
Hyperhomocysteinemia and the Endocrine System: Implications for Atherosclerosis and Thrombosis
V Fonseca, SC Guba, LM Fink
Endocrine reviews 1999
Plasma Homocysteine Is Weakly Correlated with Plasma Endothelin and von Willebrand Factor but not with Endothelium-dependent Vasodilatation in Healthy Postmenopausal Women
GW de Valk-de Roo, CD Stehouwer, J Lambert, CG Schalkwijk, MJ van der Mooren, C Kluft, C Netelenbos
Clinical chemistry 1999
Recommended Approaches for the Laboratory Measurement of Homocysteine in the Diagnosis and Monitoring of Patients with Hyperhomocysteinaemia
SJ Moat, JR Bonham, MS Tanner, JC Allen, HJ Powers
Annals of Clinical Biochemistry 1999
Homocysteine and coronary risk
N Seshadri, K Robinson
Current Cardiology Reports 1999
Relationship Between Homocysteine and Thrombotic Disease
J Selhub, A D'angelo
The American Journal of the Medical Sciences 1998
Homocysteine as a risk factor for cardiovascular and related disease: nutritional implications
DG Weir, JM Scott
Nutrition Research Reviews 1998
The effect of homocysteine on DNA synthesis in cultured human vascular smooth muscle
L Tang, CD Mamotte, FM van Bockxmeer, RR Taylor
Atherosclerosis 1998
Plasma homocysteine concentration is increased in preeclampsia and is associated with evidence of endothelial activation
RW Powers, RW Evans, AK Majors, JI Ojimba, RB Ness, WR Crombleholme, JM Roberts
American Journal of Obstetrics and Gynecology 1998
Homocysteine and endothelial vascular function
CG Hanratty, DF McAuley, C McGurk, IS Young, GD Johnston
The Lancet 1998
Homocysteine and Atherothrombosis
FH Epstein, GN Welch, J Loscalzo
New England Journal of Medicine 1998
From microalbuminuria to hyperhomocysteinemia
K Robinson, VW Dennis
Kidney International 1998
Altérations du métabolisme de l'homocystéine et maladies cardiovasculaires
P Durand, M Prost, D Blache
Revue Française des Laboratoires 1998
Protein binding of homocysteine and other thiols in HeLa cell cultures after addition of homocysteine and copper ions
B Hultberg, A Andersson, A Isaksson
Clinica Chimica Acta 1998
Acute hyperhomocysteinaemia and endothelial dysfunction
JC Chambers, A McGregor, J Jean-Marie, JS Kooner
The Lancet 1998
Serum homocysteine level and protein intake are related to risk of microalbuminuria: The Hoorn Study11See Editorial by Robinson and Dennis, p 281
EK Hoogeveen, PJ Kostense, A Jager, RJ Heine, C Jakobs, LM Bouter, AJ Donker, CD Stehouwer
Kidney International 1998
Homocysteine-dependent Alterations in Mitochondrial Gene Expression, Function and Structure: HOMOCYSTEINE AND H 2 O 2 ACT SYNERGISTICALLY TO ENHANCE MITOCHONDRIAL DAMAGE
RC Austin, SK Sood, AM Dorward, G Singh, SG Shaughnessy, S Pamidi, PA Outinen, JI Weitz
The Journal of biological chemistry 1998
Tissue Plasminogen Activator Binding to the Annexin II Tail Domain: DIRECT MODULATION BY HOMOCYSTEINE
KA Hajjar, L Mauri, AT Jacovina, F Zhong, UA Mirza, JC Padovan, BT Chait
The Journal of biological chemistry 1998
Induction of Acute Translational Response Genes by Homocysteine: ELONGATION FACTORS-1α, -β, AND -δ
G Chacko, Q Ling, KA Hajjar
The Journal of biological chemistry 1998
HIGH HOMOCYSTEINE, LOW FOLATE, AND LOW VITAMIN B6 CONCENTRATIONS: Prevalent Risk Factors for Vascular Disease in Heart Transplant Recipients
A Gupta, A Moustapha, DW Jacobsen, M Goormastic, EM Tuzcu, R Hobbs, J Young, K James, P McCarthy, F van Lente, R Green, K Robinson
Transplantation 1998
5-Methyltetrahydrofolate, the Active Form of Folic Acid, Restores Endothelial Function in Familial Hypercholesterolemia
MC Verhaar, RM Wever, JJ Kastelein, T van Dam, HA Koomans, TJ Rabelink
Circulation 1998
Prospective Study of Hyperhomocysteinemia as an Adverse Cardiovascular Risk Factor in End-Stage Renal Disease
A Moustapha, A Naso, M Nahlawi, A Gupta, KL Arheart, DW Jacobsen, K Robinson, VW Dennis
Circulation 1998
Generation and initial characterization of a novel polyclonal antibody directed against homocysteine thiolactone-modified low density lipoprotein
E Ferguson, S Parthasarathy, J Joseph, B Kalyanaraman
Journal of lipid research 1998
Perspectives series: host/pathogen interactions. Mechanisms of nitric oxide-related antimicrobial activity
FC Fang
Journal of Clinical Investigation 1997
The cell-damaging effects of low amounts of homocysteine and copper ions in human cell line cultures are caused by oxidative stress
B Hultberg, A Andersson, A Isaksson
Toxicology 1997
HOMOCYSTEINE AND VASCULAR DYSFUNCTION
SR Lentz
Life Sciences 1997
Folate and risk of cardiovascular disease
HJ Powers
Nutrition & Food Science 1997
Homocysteinemia and Endothelial Damage after Methionine Load
J Hladovec, Z Sommerová, A Písařiacute;ková
Thrombosis Research 1997
Cloning and characterization of TDD5, an androgen target gene that is differentially repressed by testosterone and dihydrotestosterone
TM Lin, C Chang
Proceedings of the National Academy of Sciences 1997
Homocysteine, Oxidative Stress, and Vascular Disease
GN Welch, GR Upchurch, J Loscalzo
Hospital Practice 1997
Inherited Hypercoagulable States
AK Rao, S Sheth, R Kaplan
Vascular medicine (London, England) 1997
Consequences of Hyperhomocyst(e)inemia on Vascular Function in Atherosclerotic Monkeys
SR Lentz, MR Malinow, DJ Piegors, M Bhopatkar-Teredesai, FM Faraci, DD Heistad
Arteriosclerosis, thrombosis, and vascular biology 1997
Hyperhomocyst(e)inemia Is Associated With Impaired Endothelium-Dependent Vasodilation in Humans
A Tawakol, T Omland, M Gerhard, JT Wu, MA Creager
Circulation 1997
Putative mechanisms for vascular damage by homocysteine
MF Bellamy, IF McDowell
Journal of Inherited Metabolic Disease 1997
Homocysteine and Thrombotic Disease
A D'Angelo, J Selhub
Blood 1997
Oxidative Stress
A Stern
Oxidative Stress 1985

← Previous 1 2 3 … 24 25 Next →

Advertisement

Copyright © 2025 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)

Sign up for email alerts