JCI - Citations to Targeted tumor killing via an intracellular antibody against erbB-2.

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Targeted tumor killing via an intracellular antibody against erbB-2.

J Deshane, … , M Kay, D T Curiel

J Deshane, … , M Kay, D T Curiel

Published December 1, 1995
Citation Information: J Clin Invest. 1995;96(6):2980-2989. https://doi.org/10.1172/JCI118370.

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Citations to this article (75)

Title and authors	Publication	Year
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A Small Virus to Deliver Small Antibodies: New Targeted Therapies Based on AAV Delivery of Nanobodies N Silva-Pilipich, C Smerdou, L Vanrell	Microorganisms	2021
Neutralizing Anti-Hemagglutinin Monoclonal Antibodies Induced by Gene-Based Transfer Have Prophylactic and Therapeutic Effects on Influenza Virus Infection T Yamazaki, J Chiba, S Akashi-Takamura	Human vaccines	2018
Antibody Engineering T Böldicke		2018
Targeted Intracellular Delivery of Antibodies: The State of the Art TA Slastnikova, AV Ulasov, AA Rosenkranz, AS Sobolev	Frontiers in pharmacology	2018
HCaRG/COMMD5 inhibits ErbB receptor-driven renal cell carcinoma H Matsuda, CG Campion, K Fujiwara, J Ikeda, S Cossette, T Verissimo, M Ogasawara, L Gaboury, K Saito, K Yamaguchi, S Takahashi, M Endo, N Fukuda, M Soma, P Hamet, J Tremblay	Oncotarget	2017
State of play and clinical prospects of antibody gene transfer K Hollevoet, PJ Declerck	Journal of Translational Medicine	2017
The antitumor efficacy of a novel adenovirus-mediated anti-p21Ras single chain fragment variable antibody on human cancers in vitro and in vivo JL Yang, XY Pan, WX Zhao, QC Hu, F Ding, Q Feng, GY Li, Y Luo	International journal of oncology	2016
A bispecific transmembrane antibody simultaneously targeting intra- and extracellular epitopes of the epidermal growth factor receptor inhibits receptor activation and tumor cell growth: Bispecific transmembrane antibody targeting EGFR N Müller, C Hartmann, S Genßler, J Koch, A Kinner, M Grez, WS Wels	International Journal of Cancer	2013
The use of phage display to generate conformation-sensor recombinant antibodies A Haque, NK Tonks	Nature Protocols	2012
State of the art in tumor antigen and biomarker discovery K Even-Desrumeaux, D Baty, P Chames	Cancers	2011
Analysis of promoters and expression-targeted gene therapy optimization based on doubling time and transfectability GL Dobek, X Zhang, DA Balazs, WT Godbey	The FASEB Journal	2011
Monoclonal Antibody and Peptide-Targeted Radiotherapy of Cancer K Ottolino-Perry, JA McCart	Monoclonal Antibody and Peptide-Targeted Radiotherapy of Cancer	2010
Persistent expression of biologically active anti-HER2 antibody by AAVrh.10-mediated gene transfer G Wang, J Qiu, R Wang, A Krause, JL Boyer, NR Hackett, RG Crystal	Cancer Gene Therapy	2010
Intrabody and Parkinson's disease C Zhou, S Przedborski	Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease	2009
Therapeutic Antibodies Y Chernajovsky, A Nissim		2008
Adenoviral vectors for gene therapy JT Douglas	Molecular Biotechnology	2007
Novel antibodies as anticancer agents I Zafir-Lavie, Y Michaeli, Y Reiter	Oncogene	2007
Gene therapy of gynaecological diseases A Kanerva, M Raki, A Hemminki	Expert Opinion on Biological Therapy	2007
Intra-arterial adenoviral mediated tumor transfection in a novel model of cancer gene therapy G Cabrera, SL Porvasnik, PE DiCorleto, M Siemionow, CK Goldman	Molecular Cancer	2006
Inhibition of Papillomavirus Protein Function in Cervical Cancer Cells by Intrabody Targeting H Griffin, R Elston, D Jackson, K Ansell, M Coleman, G Winter, J Doorbar	Journal of Molecular Biology	2006
Gene Transfer Approaches for Gynecological Diseases M Raki, DT Rein, A Kanerva, A Hemminki	Molecular Therapy	2006
Potential applications of intracellular antibodies (intrabodies) in stem cell therapeutics BC Heng, DM Kemeny, H Liu, T Cao	Journal of Cellular and Molecular Medicine	2005
Making cell-permeable antibodies (Transbody) through fusion of protein transduction domains (PTD) with single chain variable fragment (scFv) antibodies: Potential advantages over antibodies expressed within the intracellular environment (Intrabody) BC Heng, T Cao	Medical Hypotheses	2005
Phenotypic knockout of VEGF-R2 and Tie-2 with an intradiabody reduces tumor growth and angiogenesis in vivo N Jendreyko, M Popkov, C Rader, CF 3rd	Proceedings of the National Academy of Sciences	2005
Cancer Gene Therapy M Yamamoto, DT Curiel	Technology in cancer research & treatment	2005
Antibodies and gene therapy: teaching old ‘magic bullets’ new tricks L Sanz, B Blanco, L Álvarez-Vallina	Trends in Immunology	2004
Intrabodies: production and promise MR Stocks	Drug Discovery Today	2004
Ablating CAR and Integrin Binding in Adenovirus Vectors Reduces Nontarget Organ Transduction and Permits Sustained Bloodstream Persistence Following Intraperitoneal Administration M Akiyama	Molecular Therapy	2004
Inhibition of endothelial cell surface expression of vascular endothelial growth factor receptor-2 using an intrabody strategy Yurong Yang Wheeler, Timothy E. Kute, Mark C. Willingham, Si-Yi Chen, David C. Sane	The FASEB Journal	2003
Intracellular antibodies and challenges facing their use as therapeutic agents MN Lobato, TH Rabbitts	Trends in Molecular Medicine	2003
Gene and Cell Therapy: Therapeutic Mechanisms and Strategies, Second Edition, Revised and Expanded H Heslop, M Brenner, C Bollard	Gene and Cell Therapy: Therapeutic Mechanisms and Strategies, Second Edition, Revised and Expanded	2003
Intradiabodies, Bispecific, Tetravalent Antibodies for the Simultaneous Functional Knockout of Two Cell Surface Receptors N Jendreyko, M Popkov, RR Beerli, J Chung, DB McGavern, C Rader, CF Barbas	The Journal of biological chemistry	2003
Intrabody and intrakine strategies for molecular therapy YY Wheeler, SY Chen, DC Sane	Molecular Therapy	2003
Abrogation of hepatitis C virus NS3 helicase enzymatic activity by recombinant human antibodies O Artsaenko, K Tessmann, M Sack, D Häussinger, T Heintges	Journal of General Virology	2003
Characterization of anti-cyclin E single-chain Fv antibodies and intrabodies in breast cancer cells: enhanced intracellular stability of novel sFv–Fc intrabodies RW Strube, SY Chen	Journal of Immunological Methods	2002
Cloning and molecular characterization of human high affinity antibody fragments against Hepatitis C virus NS3 helicase K Tessmann, A Erhardt, D Häussinger, T Heintges	Journal of Virological Methods	2002
Gene Therapy in Lung Disease K Amin	Gene Therapy in Lung Disease	2002
Intratumoral administration of an adenovirus expressing a kinase dead form of ErbB-2 inhibits tumor growth K Palmer, N Sharan, P Emtage, J Gauldie, WJ Muller, Y Wan	Gene Therapy	2002
Genetically Engineered Intracellular Single-Chain Antibodies in Gene Therapy G Bilbao, JL Contreras, DT Curiel	Molecular Biotechnology	2002
Intracellular Stability of Anti-caspase-3 Intrabodies Determines Efficacy in Retargeting the Antigen A Rajpal, TG Turi	The Journal of biological chemistry	2001
Thoracic Oncology DS Ettinger		2001
Using a Tropism-Modified Adenoviral Vector to Circumvent Inhibitory Factors in Ascites Fluid JL Blackwell, H Li, J Gomez-Navarro, I Dmitriev, V Krasnykh, CA Richter, DR Shaw, RD Alvarez, DT Curiel, TV Strong	Human Gene Therapy	2000
Role of HER2 gene overexpression in breast carcinoma S M�nard, E Tagliabue, M Campiglio, SM Pupa	Journal of Cellular Physiology	2000
Sensitivity of c&hyphen;erbB Positive Cells to a Ligand Toxin and Its Utility in Purging Breast Cancer Cells from Peripheral Blood Stem Cell (PBSC) Collections M Keir, R Fiddes, JC Biggs, PP Kearney	Stem Cells	2000
Adenovirus-mediated ribozyme targeting of HER-2/neu inhibits in vivo growth of breast cancer cells T Suzuki, B Anderegg, T Ohkawa, A Irie, O Engebraaten, M Halks-Miller, PS Holm, DT Curiel, M Kashani-Sabet, KJ Scanlon	Gene Therapy	2000
Gene Therapy for Lung Cancer PJ Mosca, MA Morse, TA D'Amico, J Crawford, HK Lyerly	Clinical Lung Cancer	2000
Molecular and Genetic Aspects of Lung Cancer WN Rom, JG Hay, TC Lee, Y Jiang, KM Tchou-Wong	American journal of respiratory and critical care medicine	2000
Advances in cancer gene therapy G Bilbao, JL Contreras, DT Curiel	Expert Opinion on Therapeutic Patents	1999
Rapid production of specific vaccines for lymphoma by expression of the tumor-derived single-chain Fv epitopes in tobacco plants AA McCormick, MH Kumagai, K Hanley, TH Turpen, I Hakim, LK Grill, D Tusé, S Levy, R Levy	Proceedings of the National Academy of Sciences	1999
Extended half-life and elevated steady-state level of a single-chain Fv intrabody are critical for specific intracellular retargeting of its antigen, caspase-7 Q Zhu, C Zeng, A Huhalov, J Yao, TG Turi, D Danley, T Hynes, Y Cong, D DiMattia, S Kennedy, G Daumy, E Schaeffer, WA Marasco, JS Huston	Journal of Immunological Methods	1999
Characterization and Binding of Intracellular Antibody Fragments to the Hepatitis C Virus Core Protein1,2 T Heintges, J Putlitz, JR Wands	Biochemical and Biophysical Research Communications	1999
Gene therapy for carcinoma of the breast: Genetic ablation strategies DT Curiel	Breast Cancer Research	1999
Suppression of the c-erbB-2 gene product decreases transformation abilities but not the proliferation and secretion of proteases of SK-OV-3 ovarian cancer cells K Wiechen, S Karaaslan, A Turzynski, M Dietel	British Journal of Cancer	1999
A role for intracellular immunization in chemosensitization of tumor cells? A Piché, C Rancourt	Gene Therapy	1999
c-erbB-2 as a target for immunotherapy S Eccles	Expert Opinion on Investigational Drugs	1998
The Genetics of Ovarian Cancer SE DePasquale, A Giordano, AE Donnenfeld	Obstetrical & Gynecological Survey	1998
Genetically Engineered Antibodies in Gene Transfer and Gene Therapy M Pelegrin, M Marin, D Noël, M Piechaczyk	Human Gene Therapy	1998
Establishment and characterization of a new mammary adenocarcinoma cell line derived from MMTV neu transgenic mice MG Sacco, L Gribaldo, O Barbieri, G Turchi, I Zucchi, A Collotta, L Bagnasco, D Barone, C Montagna, A Villa, E Marafante, P Vezzoni	Breast Cancer Research and Treatment	1998
GENE THERAPY FOR LUNG CANCER SM Dubinett, PW Miller, S Sharma, RK Batra	Hematology/Oncology Clinics of North America	1998
Radiosensitization mediated by a transfected Anti-erbB-2 single-chain antibody in vitro and in vivo MA Stackhouse, DJ Buchsbaum, WE Grizzle, SJ Bright, CC Olsen, S Kancharla, MS Mayo, DT Curiel	International journal of radiation oncology, biology, physics	1998
Intracellular Expression of the Anti-erbB-2 sFv N29 Fails to Accomplish Efficient Target Modulation JE Grim, GP Siegal, RD Alvarez, DT Curiel	Biochemical and Biophysical Research Communications	1998
Transductional Efficacy and Safety of an Intraperitoneally Delivered Adenovirus Encoding an Anti-erbB-2 Intracellular Single-Chain Antibody for Ovarian Cancer Gene Therapy J Deshane, GP Siegal, M Wang, M Wright, RP Bucy, RD Alvarez, DT Curiel	Gynecologic Oncology	1997
A Novel Gene Therapy Strategy for Elimination of Prostate Carcinoma Cells from Human Bone Marrow M Kim, M Wright, J Deshane, MA Accavitti, A Tilden, M Saleh, WP Vaughan, MH Carabasi, MD Rogers, RD Hockett, WE Grizzle, DT Curiel	Human Gene Therapy	1997
Conditionally replicative adenoviruses for cancer therapy C Rancourt	Advanced Drug Delivery Reviews	1997
Tumor localization of a radiolabeled bombesin analogue in mice bearing human ovarian tumors induced to express the gastrin-releasing peptide receptor by an adenoviral vector BE Rogers, DT Curiel, MS Mayo, KK Laffoon, SJ Bright, DJ Buchsbaum	Cancer	1997
Antibody engineering MS Hayden, LK Gilliland, JA Ledbetter	Current Opinion in Immunology	1997
Gene therapy strategies for carcinoma of the breast JM Ruppert, M Wright, M Rosenfeld, J Grushcow, G Bilbao, DT Curiel, TV Strong	Breast Cancer Research and Treatment	1997
Gene Therapy for Lung Cancer and Mesothelioma SM Albelda	Chest	1997
Intracellular Antibodies A Cattaneo, S Biocca		1997
The maturation of human gene therapy T Friedmann	Acta Paediatrica	1996
Section Review Oncologic, Endocrine & Metabolic: Gene therapy for cancer therapeutics G Bilbao, DT Curiel	Expert Opinion on Therapeutic Patents	1996
Adenoviral-mediated delivery of herpes simplex virus thymidine kinase results in tumor reduction and prolonged survival in a SCID mouse model of human ovarian carcinoma ME Rosenfeld, M Wang, GP Siegal, RD Alvarez, G Mikheeva, V Krasnykh, DT Curiel	Journal of Molecular Medicine	1996
Advances in Pharmacology B Drenger, Y Ginosar, Y Gozal	Advances in Pharmacology	1994
New Comprehensive Biochemistry S Yamamoto	New Comprehensive Biochemistry	1983

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