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W W Li, … , J L Breslow, T Leff
Published December 1, 1995
Citation Information: J Clin Invest. 1995;96(6):2601-2605. https://doi.org/10.1172/JCI118324.
Citation Information: J Clin Invest. 1995;96(6):2601-2605. https://doi.org/10.1172/JCI118324.
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W W Li, M M Dammerman, J D Smith, S Metzger, J L Breslow, T Leff
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Citations to this article (214)
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Neuroscience Letters | 2005 |
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Determination of the Functionality of Common APOA5 Polymorphisms
PJ Talmud, J Palmen, W Putt, L Lins, SE Humphries |
The Journal of biological chemistry | 2005 |
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APOC3/A5 haplotypes, lipid levels, and risk of myocardial infarction in the Central Valley of Costa Rica
EA Ruiz-Narváez, Y Yang, Y Nakanishi, J Kirchdorfer, H Campos |
Journal of lipid research | 2005 |
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Apolipoprotein C-III, n-3 Polyunsaturated Fatty Acids, and “Insulin-Resistant” T−455C APOC3 Gene Polymorphism in Heart Disease Patients: Example of Gene-Diet Interaction
O Olivieri, N Martinelli, M Sandri, A Bassi, P Guarini, E Trabetti, F Pizzolo, D Girelli, S Friso, PF Pignatti, R Corrocher |
Clinical chemistry | 2005 |
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Mechanisms, Significance and Treatment of Vascular Dysfunction in Type 2 Diabetes Mellitus: Focus on Lipid-Regulating Therapy
RJ Woodman, GT Chew, GF Watts |
Drugs | 2005 |
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Foxo1 Mediates Insulin Action on ApoC-III and Triglyceride Metabolism
Jennifer Altomonte, Lin Cong, Sonal Harbaran, Anja Richter, Jing Xu, Marcia Meseck, Domenico Accili, Hengjiang Dong |
Journal of Clinical Investigation | 2004 |
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The role and mode of action of apolipoproteins CIII and AV: synergistic actors in triglyceride metabolism?
KW van Dijk, PC Rensen, PJ Voshol, LM Havekes |
Current Opinion in Lipidology | 2004 |
|
Population prevalence of APOE, APOC3 and PPAR-? mutations associated to hypertriglyceridemia in French Canadians
C Garenc, S Aubert, J Laroche, J Girouard, MC Vohl, J Bergeron, F Rousseau, P Julien |
Journal of Human Genetics | 2004 |
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Apolipoprotein C-III protein concentrations and gene polymorphisms in type 1 diabetes: associations with lipoprotein subclasses
Richard L Klein, M Brent McHenry, Kerry H Lok, Steven J Hunter, Ngoc-Anh Le, Alicia J Jenkins, Deyi Zheng, Andrea J Semler, W Virgil Brown, Timothy J Lyons, W Timothy Garvey, |
Metabolism | 2004 |
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APOA5 gene variants, lipoprotein particle distribution, and progression of coronary heart disease: results from the LOCAT study
PJ Talmud, S Martin, MR Taskinen, MH Frick, MS Nieminen, YA Kesäniemi, A Pasternack, SE Humphries, M Syvänne |
Journal of lipid research | 2004 |
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Variation in USF1 shows haplotype effects, gene : gene and gene : environment associations with glucose and lipid parameters in the European Atherosclerosis Research Study II
W Putt, J Palmen, V Nicaud, DA Tregouet, N Tahri-Daizadeh, DM Flavell, SE Humphries, PJ Talmud |
Human Molecular Genetics | 2004 |
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Influence of the APOA5 locus on plasma triglyceride, lipoprotein subclasses, and CVD risk in the Framingham Heart Study
CQ Lai, S Demissie, LA Cupples, Y Zhu, X Adiconis, LD Parnell, D Corella, JM Ordovas |
Journal of lipid research | 2004 |
|
Hepatic Nuclear Factor 3 and Nuclear Factor 1 Regulate 5-Aminolevulinate Synthase Gene Expression and Are Involved in Insulin Repression
ME Scassa, AS Guberman, JM Ceruti, ET Cánepa |
The Journal of biological chemistry | 2004 |
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The effects of scale: variation in the APOA1/C3/A4/A5 gene cluster
AG Clark, DA Nickerson, KM Weiss, V Salomaa, E Boerwinkle, SM Fullerton, AV Buchanan, VA Sonpar, JH Stengrd, JD Smith, SL Taylor, CS Carlson |
Human Genetics | 2004 |
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Population prevalence of APOE, APOC3 and PPAR-α mutations associated to hypertriglyceridemia in French Canadians
C Garenc, S Aubert, J Laroche, J Girouard, MC Vohl, J Bergeron, F Rousseau, P Julien |
Journal of Human Genetics | 2004 |
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Influence of polymorphism (RFLP-sstI) at the apolipoprotein C-III gene locus on the lipoprotein metabolism and insulin resistance in essential hypertensive patients. Interaction between gender and genetic polymorphism
A Espino-Montoro, M Barrios-Artillo, JM López-Chozas, A Cayuela, P Stiefel, J Villar |
Nutrition, Metabolism and Cardiovascular Diseases | 2003 |
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Chylomicron remnant metabolism studied with a new breath test in postmenopausal women with and without type 2 diabetes mellitus
CA Dane-Stewart, GF Watts, PH Barrett, BG Stuckey, JC Mamo, IJ Martins, TG Redgrave |
Clinical Endocrinology | 2003 |
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APOA5—a recent addition to genes determining plasma triglycerides
PJ Talmud |
International Congress Series | 2003 |
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Dyslipidemia in the era of HIV protease inhibitors
JH Stein |
Progress in Cardiovascular Diseases | 2003 |
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Long-term effect of reduced carbohydrate or increased fiber intake on LDL particle size and HDL composition in subjects with type 2 diabetes
TM Wolever, EB Tsihlias, MI McBurney, NA Le |
Nutrition Research | 2003 |
|
Variants in the APOC3 promoter insulin responsive element modulate insulin secretion and lipids in middle-aged men
D M Waterworth, P J Talmud, J Luan, D M Flavell, C D Byrne, S E Humphries, N J Wareham |
Biochimica et Biophysica Acta | 2003 |
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Contribution of APOA5 gene variants to plasma triglyceride determination and to the response to both fat and glucose tolerance challenges
Steve Martin, Viviane Nicaud, Steve E Humphries, Philippa J Talmud, |
Biochimica et Biophysica Acta | 2003 |
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Apolipoprotein C-III, metabolic syndrome, and risk of coronary artery disease
O Olivieri, A Bassi, C Stranieri, E Trabetti, N Martinelli, F Pizzolo, D Girelli, S Friso, PF Pignatti, R Corrocher |
Journal of lipid research | 2003 |
|
Inhibition of Foxo1 function is associated with improved fasting glycemia in diabetic mice
J Altomonte, A Richter, S Harbaran, J Suriawinata, J Nakae, SN Thung, M Meseck, D Accili, H Dong |
American journal of physiology. Endocrinology and metabolism | 2003 |
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Effect of apoC-III gene polymorphisms on the lipoprotein-lipid profile of viscerally obese men
C Couillard, MC Vohl, JC Engert, I Lemieux, A Houde, N Alméras, D Prud'homme, A Nadeau, JP Després, J Bergeron |
Journal of lipid research | 2003 |
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Cardiovascular Risk in Type 2 Diabetes Mellitus
N Hâncu |
2003 | |
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Gene Polymorphism and Coronary Risk Factors in Indian Population
TF Ashavaid, KK Shalia, AA Kondkar, SP Todur, KG Nair, SR Nair |
Clinical Chemistry and Laboratory Medicine | 2002 |
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Genetic determinants of the response to bezafibrate treatment in the lower extremity arterial disease event reduction (LEADER) trial
Y Jamshidi, DM Flavell, E Hawe, PK MacCallum, TW Meade, SE Humphries |
Atherosclerosis | 2002 |
|
Abundant Raw Material for Cis-Regulatory Evolution in Humans
MV Rockman, GA Wray |
Molecular Biology and Evolution | 2002 |
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Análisis de las regiones reguladoras de la expresión de apo A-I en sujetos con hipoalfalipoproteinemia
D Recalde, A Cenarro, AL García-Otín, T Tejedor, F Civeira, M Pocoví |
Clínica e Investigación en Arteriosclerosis | 2002 |
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Identification of Rev-erbα as a physiological repressor of apoC-III gene transcription
E Raspé, H Duez, A Mansén, C Fontaine, C Fiévet, JC Fruchart, B Vennström, B Staels |
Journal of lipid research | 2002 |
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ApoC-III gene polymorphisms and risk of coronary artery disease
O Olivieri, C Stranieri, A Bassi, B Zaia, D Girelli, F Pizzolo, E Trabetti, S Cheng, MA Grow, PF Pignatti, R Corrocher |
Journal of lipid research | 2002 |
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Fructose Intake Increases Hyperlipidemia and Modifies Apolipoprotein Expression in Apolipoprotein AI-CIII-AIV Transgenic Mice
MA Ostos, D Recalde, N Baroukh, A Callejo, M Rouis, G Castro, MM Zakin |
The Journal of nutrition | 2002 |
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Association Between the PPARA L162V Polymorphism and Plasma Lipid Levels: The Framingham Offspring Study
ES Tai, S Demissie, LA Cupples, D Corella, PW Wilson, EJ Schaefer, JM Ordovas |
Arteriosclerosis, thrombosis, and vascular biology | 2002 |
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Associations of LPL and APOC3 gene polymorphisms on plasma lipids in a Mediterranean population: interaction with tobacco smoking and the APOE locus
D Corella, M Guillén, C Sáiz, O Portolés, A Sabater, J Folch, JM Ordovas |
Journal of lipid research | 2002 |
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An interaction between apo C-III variants and protease inhibitors contributes to high triglyceride/low HDL levels in treated HIV patients
J Fauvel, E Bonnet, JB Ruidavets, J Ferrières, A Toffoletti, P Massip, H Chap, B Perret |
AIDS | 2001 |
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Association of the Sst-I polymorphism at the APOC3 gene locus with variations in lipid levels, lipoprotein subclass profiles and coronary heart disease risk: the Framingham offspring study
GT Russo, JB Meigs, LA Cupples, S Demissie, JD Otvos, PW Wilson, C Lahoz, D Cucinotta, P Couture, T Mallory, EJ Schaefer, JM Ordovas |
Atherosclerosis | 2001 |
|
Genetic determinants of plasma triglycerides: Impact of rare and common mutations
PJ Talmud |
Current Atherosclerosis Reports | 2001 |
|
Apolipoproteins C-I and C-III as important modulators of lipoprotein metabolism
NS Shachter |
Current Opinion in Lipidology | 2001 |
|
Age-Associated Accumulation of the Apolipoprotein C-III Gene T-455C Polymorphism C Allele in a Russian Population
SV Anisimov, MV Volkova, LV Lenskaya, VK Khavinson, DV Solovieva, EI Schwartz |
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences | 2001 |
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Genetic determination of plasma lipids and insulin in the Czech population
JA Hubacek, DM Waterworth, R Poledne, J Pitha, Z Škodová, SE Humphries, PJ Talmud |
Clinical Biochemistry | 2001 |
|
Prevalence of the APOC3 promoter polymorphisms T-455C and C-482T in Asian-Indians
M Miller, J Rhyne, M Khatta, H Parekh, K Zeller |
The American Journal of Cardiology | 2001 |
|
Phosphatidylinositol 3-Kinase and Ras/Mitogen-Activated Protein Kinase Signaling Pathways Are Required for the Regulation of 5-Aminolevulinate Synthase Gene Expression by Insulin
ME Scassa, AS Guberman, CL Varone, ET Cánepa |
Experimental Cell Research | 2001 |
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Polymorphisms in the insulin response element of APOC-III gene promoter influence the correlation between insulin and triglycerides or triglyceride-rich lipoproteins in humans
J Dallongeville, A Meirhaeghe, D Cottel, JC Fruchart, P Amouyel, N Helbecque |
International Journal of Obesity | 2001 |
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Apoprotein C-III and E-Containing Lipoparticles Are Markedly Increased in HIV-Infected Patients Treated with Protease Inhibitors: Association with the Development of Lipodystrophy
E Bonnet, JB Ruidavets, J Tuech, J FerriÈres, X Collet, J Fauvel, P Massip, B Perret |
The Journal of clinical endocrinology and metabolism | 2001 |
|
Genetic heterogeneity in the apolipoprotein C-III promoter and effects of insulin
GM Dallinga-Thie, M Groenendijk, RN Blom, TW Bruin, ED Kant |
Journal of lipid research | 2001 |
|
Candidate genes and confirmed genetic polymorphisms associated with cardiovascular diseases: a tabular assessment
Z Tang, R P Tracy |
Journal of Thrombosis and Thrombolysis | 2001 |
|
Delayed catabolism of apoB48 lipoproteins in streptozotocin-treated mice: evidence that diabetes leads to a selective alteration in the heparan sulfate proteoglycan pathway of chylomicron remnant degradation
Tetsu Ebara, Karin Conde, Yuko Kako, Yan Xu, Rajasekhar Ramakrishnan, Ira J. Goldberg, Neil S. Shachter |
Journal of Clinical Investigation | 2000 |
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Postprandial lipemia and coronary risk
W Patsch, H Esterbauer, B Föger, JR Patsch |
Current Atherosclerosis Reports | 2000 |
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In-vivo and in-vitro nutrient-gene interactions
PJ Talmud, DM Waterworth |
Current Opinion in Lipidology | 2000 |
|
Postprandial concentrations and distribution of apo C-III in type 2 diabetic patients. Effect of bezafibrate treatment
N Attia, V Durlach, M Cambilleau, D Roche, A Girard-Globa |
Atherosclerosis | 2000 |
|
Genetic determinants of plasma lipid response to dietary intervention: the role of the APOA1/C3/A4 gene cluster and the APOE gene
JM Ordovas, EJ Schaefer |
British Journal of Nutrition | 2000 |
|
GENETICS OFLIPOPROTEINABNORMALITIESASSOCIATED WITHCORONARYHEARTDISEASESUSCEPTIBILITY
JL Breslow |
Annual Review of Genetics | 2000 |
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Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR
J Nakae, V Barr, D Accili |
The EMBO Journal | 2000 |
|
Le rôle de ses activateurs dans la régulation de l'expression des gènes impliqués dans le métabolisme des lipoprotéines, l'inflammation vasculaire et l'athérosclérose
P Duriez, B Staels, JC Fruchart |
Annales de l'Institut Pasteur/Actualit�s | 2000 |
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A Nucleoprotein Complex containing CCAAT/Enhancer-binding Protein β Interacts with an Insulin Response Sequence in the Insulin-like Growth Factor-binding Protein-1 Gene and Contributes to Insulin-regulated Gene Expression
AK Ghosh, R Lacson, P Liu, SB Cichy, A Danilkovich, S Guo, TG Unterman |
The Journal of biological chemistry | 2000 |
|
Contribution of Apolipoprotein C-III Gene Variants to Determination of Triglyceride Levels and Interaction With Smoking in Middle-Aged Men
DM Waterworth, PJ Talmud, SR Bujac, RM Fisher, GJ Miller, SE Humphries |
Arteriosclerosis, thrombosis, and vascular biology | 2000 |
|
Plasma levels of remnant particles are determined in part by variation in the APOC3 gene insulin response element and the APOCI–APOE cluster
DM Waterworth, JA Hubacek, J Pitha, J Kovar, R Poledne, SE Humphries, PJ Talmud |
Journal of lipid research | 2000 |
|
Metabolic Complications of Obesity
SM Grundy |
Endocrine | 2000 |
|
Insulin resistance and familial dyslipidaemias
JF Ascaso, JT Real, R Carmena |
Diabetes, Obesity and Metabolism | 1999 |
|
Peroxisome proliterator-activated receptor-alpha activators regulate genes governing lipoprotein metabolism, vascular inflammation and atherosclerosis
JC Fruchart, P Duriez, B Staels |
Current Opinion in Lipidology | 1999 |
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Lessons from Genetic Studies in Native Canadian Populations
RA Hegele |
Nutrition Reviews | 1999 |
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Genetic prediction of atherosclerosis: lessons from studies in native Canadian populations
RA Hegele |
Clinica Chimica Acta | 1999 |
|
Delineation of the insulin-responsive sequence in the rat cytosolic aspartate aminotransferase gene: binding sites for hepatocyte nuclear factor-3 and nuclear factor I
F Beurton, U Bandyopadhyay, B Dieumegard, R Barouki, M Aggerbeck |
Biochemical Journal | 1999 |
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ApoCIII gene variants modulate postprandial response to both glucose and fat tolerance tests
DM Waterworth, J Ribalta, V Nicaud, J Dallongeville, SE Humphries, P Talmud |
Circulation | 1999 |
|
Severe hyperlipidemia in apolipoprotein E2 homozygotes due to a combined effect of hyperinsulinemia and an SstI polymorphism
EJ Sijbrands, MJ Hoffer, AE Meinders, LM Havekes, RR Frants, AH Smelt, PD Knijff |
Arteriosclerosis, thrombosis, and vascular biology | 1999 |
|
Genetic prediction of coronary heart disease: Lessons from Canada
RA Hegele |
Scandinavian Journal of Clinical & Laboratory Investigation | 1999 |
|
Mitogen-activated Protein Kinase Regulates Transcription of the ApoCIII Gene: INVOLVEMENT OF THE ORPHAN NUCLEAR RECEPTOR HNF4
S Reddy, W Yang, DG Taylor, X Shen, D Oxender, G Kust, T Leff |
The Journal of biological chemistry | 1999 |
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Phosphorylation of Serine 256 by Protein Kinase B Disrupts Transactivation by FKHR and Mediates Effects of Insulin on Insulin-like Growth Factor-binding Protein-1 Promoter Activity through a Conserved Insulin Response Sequence
S Guo, G Rena, S Cichy, X He, P Cohen, T Unterman |
The Journal of biological chemistry | 1999 |
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Multiple Promoter Elements Are Required for the Stimulatory Effect of Insulin on Human Collagenase-1 Gene Transcription: SELECTIVE EFFECTS ON ACTIVATOR PROTEIN-1 EXPRESSION MAY EXPLAIN THE QUANTITATIVE DIFFERENCE IN INSULIN AND PHORBOL ESTER ACTION
SC Chapman, JE Ayala, RS Streeper, AA Culbert, EM Eaton, CA Svitek, JK Goldman, JM Tavaré, RM OBrien |
The Journal of biological chemistry | 1999 |
|
Allele-specific Differences in Apolipoprotein C-III mRNA Expression in Human Liver
H Esterbauer, E Hell, F Krempler, W Patsch |
Clinical chemistry | 1999 |
|
Association of plasma lipids and apolipoproteins with the insulin response element in the apoC-III promoter region in familial combined hyperlipidemia
M Groenendijk, R, NH Blom, JI Rotter, TW de Bruin, GM Dallinga-Thie |
Journal of lipid research | 1999 |
|
Retinoids increase human apo C-III expression at the transcriptional level via the retinoid X receptor. Contribution to the hypertriglyceridemic action of retinoids
N Vu-Dac, P Gervois, IP Torra, JC Fruchart, V Kosykh, T Kooistra, HM Princen, J Dallongeville, B Staels |
Journal of Clinical Investigation | 1998 |
|
Dyslipoproteinaemia and hyperoxidative stress in the pathogenesis of endothelial dysfunction in non-insulin dependent diabetes mellitus: an hypothesis
GF Watts, DA Playford |
Atherosclerosis | 1998 |
|
Increased risk for endogenous hypertriglyceridaemia is associated with an apolipoprotein C3 haplotype specified by the SstI polymorphism
Hoffer, Sijbrands, de Man, Havekes, Smelt, Frants |
European Journal of Clinical Investigation | 1998 |
|
Genetics in childhood atherosclerosis
RA Hegele |
Progress in Pediatric Cardiology | 1998 |
|
Central Role for Phosphatidylinositide 3-Kinase in the Repression of Glucose-6-phosphatase Gene Transcription by Insulin
M Dickens, CA Svitek, AA Culbert, RM OBrien, JM Tavaré |
The Journal of biological chemistry | 1998 |
|
Protein Kinase B/Akt Mediates Effects of Insulin on Hepatic Insulin-like Growth Factor-binding Protein-1 Gene Expression through a Conserved Insulin Response Sequence
SB Cichy, S Uddin, A Danilkovich, S Guo, A Klippel, TG Unterman |
The Journal of biological chemistry | 1998 |
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Complex genetic contribution of the Apo AI-CIII-AIV gene cluster to familial combined hyperlipidemia. Identification of different susceptibility haplotypes
GM Dallinga-Thie, ML Trip, JI Rotter, RM Cantor, X Bu, AJ Lusis, TW de Bruin |
Journal of Clinical Investigation | 1997 |
|
Intestinal transcription and synthesis of apolipoprotein AI is regulated by five natural polymorphisms upstream of the apolipoprotein CIII gene
S Naganawa, HN Ginsberg, RM Glickman, GS Ginsburg |
Journal of Clinical Investigation | 1997 |
|
Chylomicronemia due to apolipoprotein CIII overexpression in apolipoprotein E-null mice. Apolipoprotein CIII-induced hypertriglyceridemia is not mediated by effects on apolipoprotein E
T Ebara, R Ramakrishnan, G Steiner, NS Shachter |
Journal of Clinical Investigation | 1997 |
|
The genetic basis of atherosclerosis
RA Hegele |
International Journal of Clinical & Laboratory Research | 1997 |
|
Small genetic effects in complex diseases: A review of regulatory sequence variants in dyslipoproteinemia and atherosclerosis
RA Hegele |
Clinical Biochemistry | 1997 |
|
A Mouse Model with Features of Familial Combined Hyperlipidemia
L Masucci-Magoulas, IJ Goldberg, CL Bisgaier, H Serajuddin, OL Francone, JL Breslow, AR Tall |
Science | 1997 |
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Inhibitory Effects of Specific Apolipoprotein C-III Isoforms on the Binding of Triglyceride-rich Lipoproteins to the Lipolysis-stimulated Receptor
CJ Mann, AA Troussard, FT Yen, N Hannouche, J Najib, JC Fruchart, V Lotteau, P André, BE Bihain |
The Journal of biological chemistry | 1997 |
|
A Multicomponent Insulin Response Sequence Mediates a Strong Repression of Mouse Glucose-6-phosphatase Gene Transcription by Insulin
RS Streeper, CA Svitek, S Chapman, LE Greenbaum, R Taub, RM OBrien |
The Journal of biological chemistry | 1997 |
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Common Genomic Variants Associated With Variation in Plasma Lipoproteins in Young Aboriginal Canadians
RA Hegele, PW Connelly, AJ Hanley, F Sun, SB Harris, B Zinman |
Arteriosclerosis, thrombosis, and vascular biology | 1997 |
|
Common Genomic Variation in the APOC3 Promoter Associated With Variation in Plasma Lipoproteins
RA Hegele, PW Connelly, AJ Hanley, F Sun, SB Harris, B Zinman |
Arteriosclerosis, thrombosis, and vascular biology | 1997 |
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Genetics of the Berardinelli-Seip syndrome (congenital generalized lipodystrophy) in Norway: epidemiology and gene mapping
T Gedde-Dahl, O Trygstad, LV Maldergem, J Magré, CB der Hagen, B Olaisen, M Stenersen, B Mevåg |
Acta Paediatrica | 1996 |
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Further characterization of the metabolic properties of triglyceride-rich lipoproteins from human and mouse apoC-III transgenic mice
K Aalto-Setälä, PH Weinstock, CL Bisgaier, L Wu, JD Smith, JL Breslow |
Journal of lipid research | 1996 |
|
Why there is an IRS
RM O'Brien, DK Granner |
Journal of Clinical Investigation | 1995 |
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International Review of Cytology
RA Miller |
International Review of Cytology | 1991 |
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