Heat shock treatment induces expression of several heat shock proteins and subsequent post-ischemic myocardial protection. Correlations exist between the degree of stress used to induce the heat shock proteins, the amount of the inducible heat shock protein 70 (HSP70) and the level of myocardial protection. The inducible HSP70 has also been shown to be protective in transfected myogenic cells. Here we examined the role of human inducible HSP70 in transgenic mouse hearts. Overexpression of the human HSP70 does not appear to affect normal protein synthesis or the stress response in transgenic mice compared with nontransgenic mice. After 30 min of ischemia, upon reperfusion, transgenic hearts versus nontransgenic hearts showed significantly improved recovery of contractile force (0.35 +/- 0.08 versus 0.16 +/- 0.05 g, respectively, P < 0.05), rate of contraction, and rate of relaxation. Creatine kinase, an indicator of cellular injury, was released at a high level (67.7 +/- 23.0 U/ml) upon reperfusion from nontransgenic hearts, but not transgenic hearts (1.6 +/- 0.8 U/ml). We conclude that high level constitutive expression of the human inducible HSP70 plays a direct role in the protection of the myocardium from ischemia and reperfusion injury.
J C Plumier, B M Ross, R W Currie, C E Angelidis, H Kazlaris, G Kollias, G N Pagoulatos
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Atherosclerosis | 2006 |
Benzo(a)pyrene inhibits expression of inducible heat shock protein 70 in vascular endothelial cells
Z Gong, J Yang, M Yang, F Wang, Q Wei, RM Tanguay, T Wu |
Toxicology Letters | 2006 |
L'agrégation toxique des protéines : une forme de « délinquance moléculaire » activement combattue dans la cellule par les chaperones moléculaires et les protéases
MP Hinault, P Goloubinoff |
Annales de Cardiologie et d Angéiologie | 2006 |
Effects of HSP70.1/3 gene knockout on acute respiratory distress syndrome and the inflammatory response following sepsis
KD Singleton, PE Wischmeyer |
American journal of physiology. Lung cellular and molecular physiology | 2006 |
Anti-inflammatory and antinecrotic effects of the volatile anesthetic sevoflurane in kidney proximal tubule cells
HT Lee, M Kim, M Jan, CW Emala |
American journal of physiology. Renal physiology | 2006 |
Overexpressed heat shock protein 70 protects cells against DNA damage caused by ultraviolet C in a dose-dependent manner
P Niu, L Liu, Z Gong, H Tan, F Wang, J Yuan, Y Feng, Q Wei, RM Tanguay, T Wu |
Cell Stress and Chaperones | 2006 |
Whole-body heat shock protects the ischemic rat heart by stimulating mitochondria respiration
TL Broderick |
Canadian Journal of Physiology and Pharmacology | 2006 |
Castration inhibits exercise-induced accumulation of Hsp70 in male rodent hearts
KJ Milne, DB Thorp, CW Melling, EG Noble |
American journal of physiology. Heart and circulatory physiology | 2006 |
Insulin induces myocardial protection and Hsp70 localization to plasma membranes in rat hearts
G Li, IS Ali, RW Currie |
American journal of physiology. Heart and circulatory physiology | 2006 |
Heat shock proteins, end effectors of myocardium ischemic preconditioning?
MC Guisasola, M del Mar Desco, FS Gonzalez, F Asensio, E Dulin, A Suarez, PG Barreno |
Cell Stress and Chaperones | 2006 |
A novel endothelial-specific heat shock protein HspA12B is required in both zebrafish development and endothelial functions in vitro
G Hu, J Tang, B Zhang, Y Lin, J Hanai, J Galloway, V Bedell, N Bahary, Z Han, R Ramchandran, B Thisse, C Thisse, LI Zon, VP Sukhatme |
Journal of cell science | 2006 |
HSP60, Bax, Apoptosis and the Heart
S Gupta, AA Knowlton |
Journal of Cellular and Molecular Medicine | 2005 |
Preconditioning with 1,25-Dihydroxyvitamin D<sub>3</sub> Protects against Subsequent Ischemia-Reperfusion Injury in the Rat Kidney
YO Kim, C Li, BK Sun, JS Kim, SW Lim, BS Choi, YS Kim, J Kim, BK Bang, CW Yang |
Nephron Experimental Nephrology | 2005 |
Geranylgeranylacetone ameliorates ischemic acute renal failure via induction of Hsp70
S Suzuki, S Maruyama, W Sato, Y Morita, F Sato, Y Miki, S Kato, M Katsuno, G Sobue, Y Yuzawa, S Matsuo |
Kidney International | 2005 |
An anti-ulcer drug, geranylgeranylacetone, suppresses inducible nitric oxide synthase in cultured vascular smooth muscle cells
K Yamamoto, M Sarukawa, T Ito, H Aoki, M Ichida, K Shimada |
Journal of Hypertension | 2005 |
Cytoprotective Effect of 3-[2-[4-(3-Chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole Dihydrochloride 3.5 Hydrate (DY-9760e) Against Ischemia/Reperfusion-Induced Injury in Rat Heart Involves Inhibition of Fodrin Breakdown and Protein Tyrosine Nitration
M Hashimoto, Y Takada, Y Takeuchi, J Kasahara, H Hisa, Y Shirasaki, K Fukunaga |
Journal of Pharmacological Sciences | 2005 |
Age-related changes in neutral sphingomyelin-specific phospholipase C activity in striatum, hippocampus, and frontal cortex: Implication for sensitivity to stress and inflammation
NA Crivello, IH Rosenberg, GE Dallal, D Bielinski, JA Joseph |
Neurochemistry International | 2005 |
Association of High Intracellular, But Not Serum, Heat Shock Protein 70 With Postoperative Atrial Fibrillation
K Mandal, E Torsney, J Poloniecki, AJ Camm, Q Xu, M Jahangiri |
The Annals of Thoracic Surgery | 2005 |
Plasma antibodies against heat shock protein 70 correlate with the incidence and severity of asthma in a Chinese population
M Yang, T Wu, L Cheng, F Wang, Q Wei, RM Tanguay |
Respiratory Research | 2005 |
Association of hsp70-2 and hsp-hom gene polymorphisms with risk of acute high-altitude illness in a Chinese population
F Zhou, F Wang, F Li, J Yuan, H Zeng, Q Wei, RM Tanguay, T Wu |
Cell stress & chaperones | 2005 |
Role of tumour necrosis factor-alpha and other cytokines in ischemia-reperfusion-induced injury in the heart
HK Saini, YJ Xu, M Zhang, PP Liu, LA Kirshenbaum, NS Dhalla |
Experimental and clinical cardiology | 2005 |
Heat shock protein: Tracing the enemy in septic shock*
WB de Carvalho, MC Fonseca |
Pediatric Critical Care Medicine | 2005 |
THERAPEUTIC TREATMENT WITH L-ARGININE RESCUES MICE FROM HEAT STROKE-INDUCED DEATH: PHYSIOLOGICAL AND MOLECULAR MECHANISMS
S Chatterjee, S Premachandran, D Sharma, RS Bagewadikar, TB Poduval |
Shock | 2005 |
Preservation of heat stress induced myocardial hsp 72 in aged animals following caloric restriction
B Frier, M Locke |
Experimental Gerontology | 2005 |
Neuroprotective effects of HSP70 overexpression after cerebral ischaemia—An MRI study
L der Weerd, MF Lythgoe, RA Badin, LM Valentim, MT Akbar, JS de Belleroche, DS Latchman, DG Gadian |
Experimental Neurology | 2005 |
NeuroImmune Biology
R Solana, G Pawelec |
NeuroImmune Biology | 2005 |
Effect of mutation of amino acids 246–251 (KRKHKK) in HSP72 on protein synthesis and recovery from hypoxic injury
MR Voss, S Gupta, JP Stice, G Baumgarten, L Lu, JM Tristan, AA Knowlton |
American journal of physiology. Heart and circulatory physiology | 2005 |
Cytokines and cardiovascular disease
VC Mehra, VS Ramgolam, JR Bender |
Journal of leukocyte biology | 2005 |
Expression of constitutively stable hybrid hypoxia-inducible factor-1α protects cultured rat cardiomyocytes against simulated ischemia-reperfusion injury
T Date, S Mochizuki, AJ Belanger, M Yamakawa, Z Luo, KA Vincent, SH Cheng, RJ Gregory, C Jiang |
American journal of physiology. Cell physiology | 2005 |
Principles of Molecular Cardiology
MS Runge, C Patterson |
2005 | |
Sequestration of TRAF2 into Stress Granules Interrupts Tumor Necrosis Factor Signaling under Stress Conditions
WJ Kim, SH Back, V Kim, I Ryu, SK Jang |
Molecular and cellular biology | 2005 |
Protective role of heat stress in burn trauma*
DJ White, D Carlson, GA Ordway, JW Horton |
Critical Care Medicine | 2004 |
Induction of heat shock protein 70 in failing heart
K TANONAKA, W TOGA, S TAKEO |
Folia Pharmacologica Japonica | 2004 |
Cell Death Pathways in Pancreatitis and Pancreatic Cancer
AS Gukovskaya, SJ Pandol |
Pancreatology | 2004 |
The Role of Innate Immune Responses in the Heart in Health and Disease
P Knuefermann, J Vallejo, DL Mann |
Trends in Cardiovascular Medicine | 2004 |
Heat shock protein 27 protects the heart against myocardial infarction
CA Efthymiou, MM Mocanu, J Belleroche, DJ Wells, DS Latchmann, DM Yellon |
Basic Research in Cardiology | 2004 |
HSF1 blockade-induced tumor thermotolerance abolishment is mediated by JNK-dependent caspase-3 activation
JH Wang, MZ Yao, ZL Zhang, YH Zhang, YG Wang, XY Liu |
Biochemical and Biophysical Research Communications | 2004 |
Keeping up the defenses
RD Griffiths, A McArdle |
Nutrition | 2004 |
The Upregulation of Cognate and Inducible Heat Shock Proteins in the Anoxic Turtle Brain
HM Prentice, SL Milton, D Scheurle, PL Lutz |
Journal of Cerebral Blood Flow & Metabolism | 2004 |
Preconditioning: Evolution of Basic Mechanisms to Potential Therapeutic Strategies
BM Tsai, M Wang, KL March, MW Turrentine, JW Brown, DR Meldrum |
Shock | 2004 |
Cytochrome c oxidase as the target of the heat shock protective effect in septic liver
HW Chen, HT Kuo, TS Lu, SJ Wang, RC Yang |
International Journal of Experimental Pathology | 2004 |
Correlation of lymphocyte heat shock protein 70 levels with neurologic deficits in elderly patients with cerebral infarction
X Jin, C Xiao, RM Tanguay, L Yang, F Wang, M Chen, X Fu, R Wang, J Deng, Z Deng, Y Zheng, Q Wei, T Wu |
The American Journal of Medicine | 2004 |
Expression of the 60 kDa and 71 kDa heat shock proteins and presence of antibodies against the 71 kDa heat shock protein in pediatric patients with immune thrombocytopenic purpura
C Xiao, S Chen, M Yuan, F Ding, D Yang, R Wang, J Li, RM Tanguay, T Wu |
BMC Hematology | 2004 |
Protein kinase C-dependent activation of P44/42 mitogen-activated protein kinase and heat shock protein 70 in signal transduction during hepatocyte ischemic preconditioning
Yi Gao, Yu-Qiang Shan, Ming-Xin Pan, Yu Wang, Li-Jun Tang, Hao Li, Zhi Zhang |
World journal of gastroenterology : WJG | 2004 |
Heat shock treatment suppresses angiotensin II-induced activation of NF-κB pathway and heart inflammation: a role for IKK depletion by heat shock?
Y Chen, AP Arrigo, RW Currie |
American journal of physiology. Heart and circulatory physiology | 2004 |
Rapid, transient, and dose-dependent expression of Hsp70 messenger RNA in the rat brain after morphine treatment
S Ammon-Treiber, G Grecksch, R Stumm, U Riechert, H Tischmeyer, A Reichenauer, V Höllt |
Cell Stress and Chaperones | 2004 |
Heat shock treatment protects against angiotensin II–induced hypertension and inflammation in aorta
Y Chen, BM Ross, RW Currie |
Cell Stress and Chaperones | 2004 |
Radicicol activates heat shock protein expression and cardioprotection in neonatal rat cardiomyocytes
TM Griffin, TV Valdez, R Mestril |
American journal of physiology. Heart and circulatory physiology | 2004 |
Serum and lymphocyte levels of heat shock protein 70 in aging: a study in the normal Chinese population
X Jin, R Wang, C Xiao, L Cheng, F Wang, L Yang, T Feng, M Chen, S Chen, X Fu, J Deng, R Wang, F Tang, Q Wei, RM Tanguay, T Wu |
Cell Stress and Chaperones | 2004 |
Heat shock proteins can protect aged human and rodent cells from different stressful stimuli
S Alsbury, K Papageorgiou, DS Latchman |
Mechanisms of Ageing and Development | 2004 |
Enforced expression of oxygen-regulated protein, ORP150, induces vacuolar degeneration in mouse myocardium
Tomohiro Kobayashi, Yasuhiko Ohta |
Transgenic Research | 2003 |
Myocardial recovery from ischemia is impaired in CD36-null mice and restored by myocyte CD36 expression or medium-chain fatty acids
H Irie, IB Krukenkamp, JF Brinkmann, GR Gaudette, AE Saltman, W Jou, JF Glatz, NA Abumrad, A Ibrahimi |
Proceedings of the National Academy of Sciences | 2003 |
STRESS-ACTIVATEDCYTOKINES ANDTHEHEART: From Adaptation to Maladaptation1
DL Mann |
Annual Review of Physiology | 2003 |
Necrosis: a specific form of programmed cell death?
SY Proskuryakov, AG Konoplyannikov, VL Gabai |
Experimental Cell Research | 2003 |
Herbimycin A attenuates apoptosis during heat stress in rats
SB Sachidhanandam, J Lu, KS Low, SM Moochhala |
European Journal of Pharmacology | 2003 |
Preconditioned somatothermal stimulation on median nerve territory increases myocardial heat shock protein 70 and protects rat hearts against ischemia-reperfusion injury
JH Chiu, MT Tsou, HH Tung, CH Tai, SK Tsai, CL Chih, JG Lin, CW Wu |
The Journal of Thoracic and Cardiovascular Surgery | 2003 |
HSP70.1 and -70.3 are required for late-phase protection induced by ischemic preconditioning of mouse hearts
CR Hampton, A Shimamoto, CL Rothnie, J Griscavage-Ennis, A Chong, DJ Dix, ED Verrier, TH Pohlman |
American journal of physiology. Heart and circulatory physiology | 2003 |
Gender differences in the expression of heat shock proteins: the effect of estrogen
MR Voss, JN Stallone, M Li, RN Cornelussen, P Knuefermann, AA Knowlton |
American journal of physiology. Heart and circulatory physiology | 2003 |
Regulation of Necrosis of H9c2 Myogenic Cells upon Transient Energy Deprivation: RAPID DEENERGIZATION OF MITOCHONDRIA PRECEDES NECROSIS AND IS CONTROLLED BY REACTIVE OXYGEN SPECIES, STRESS KINASE JNK, HSP72, AND ARC
JA Yaglom, D Ekhterae, VL Gabai, MY Sherman |
The Journal of biological chemistry | 2003 |
Age and attenuation of exercise-induced myocardial HSP72 accumulation
HA Demirel, KL Hamilton, RA Shanely, N Tümer, MJ Koroly, SK Powers |
American journal of physiology. Heart and circulatory physiology | 2003 |
Basal and inducible levels of Hsp70 in patients with acute heat illness induced during training
C Xiao, T Wu, A Ren, Q Pan, S Chen, F Wu, X Li, R Wang, LE Hightower, RM Tanguay |
Cell Stress and Chaperones | 2003 |
Overexpression of heat shock proteins differentially modulates protein kinase C expression in rat neonatal cardiomyocytes
SD Coaxum, JL Martin, R Mestril |
Cell Stress and Chaperones | 2003 |
Heat shock protein 70 chaperone overexpression ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model by reducing nuclear-localized mutant androgen receptor protein
Hiroaki Adachi, Masahisa Katsuno, Makoto Minamiyama, Chen Sang, Gerassimos Pagoulatos, Charalampos Angelidis, Moriaki Kusakabe, Atsushi Yoshiki, Yasushi Kobayashi, Manabu Doyu, Gen Sobue |
The Journal of neuroscience : the official journal of the Society for Neuroscience | 2003 |
Preconditioning with erythropoietin protects against subsequent ischemia‐reperfusion injury in rat kidney
CW Yang, C Li, JY Jung, SJ Shin, BS Choi, SW Lim, BK Sun, YS Kim, J Kim, YS Chang, BK Bang |
The FASEB Journal | 2003 |
The heat shock-induced cell cycle arrest is attenuated by weak electromagnetic fields: Stress protection by EMF
SV Tokalov, HO Gutzeit |
Cell Proliferation | 2003 |
Heat Shock Protein 70 Chaperone Overexpression Ameliorates Phenotypes of the Spinal and Bulbar Muscular Atrophy Transgenic Mouse Model by Reducing Nuclear-Localized Mutant Androgen Receptor Protein
Adachi H, Katsuno M, Minamiyama M, Sang C, Pagoulatos G, Angelidis C, Kusakabe M, Yoshiki A, Kobayashi Y, Doyu M, Sobue G |
Journal of Neuroscience | 2003 |
The atrial natriuretic peptide and cGMP: novel activators of the heat shock response in rat livers
AK Kiemer, AL Gerbes, M Bilzer, AM Vollmar |
Hepatology | 2002 |
Wiley Encyclopedia of Molecular Medicine
WT Morgan |
Wiley Encyclopedia of Molecular Medicine | 2002 |
Encyclopedia of Molecular Biology
B Mannervik |
Encyclopedia of Molecular Biology | 2002 |
The Yin/Yang of Innate Stress Responses in the Heart
D Mann |
Cold Spring Harbor Symposia on Quantitative Biology | 2002 |
The Interaction Between HSP70 and TNF-?? Expression: A Novel Mechanism for Protection of the Myocardium Against Post-Injury Depression
X Meng, AH Harken |
Shock | 2002 |
Understanding myocardial ischemic preconditioning, and the implications for a role of adenosine catabolism
M Kavianipour |
Upsala Journal of Medical Sciences | 2002 |
Exercise and cardioprotection
SK Powers, SL Lennon, J Quindry, JL Mehta |
Current Opinion in Cardiology | 2002 |
Heat stress increases endothelium-dependent relaxations and prevents reperfusion-induced endothelial dysfunction
V Richard, K Laude, C Artigues, N Kaeffer, JP Henry, C Thuillez |
Clinical and Experimental Pharmacology and Physiology | 2002 |
Gene transfer of HSP72 protects cornu ammonis 1 region of the hippocampus neurons from global ischemia: Influence of Bcl-2
S Kelly, ZJ Zhang, H Zhao, L Xu, RG Giffard, RM Sapolsky, MA Yenari, GK Steinberg |
Annals of Neurology | 2002 |
Heat shock factor 1 and heat shock proteins: Critical partners in protection against acute cell injury
ES Christians, LJ Yan, IJ Benjamin |
Critical Care Medicine | 2002 |
Interactions between the heat shock response and the nuclear factor-κB signaling pathway
V Malhotra, HR Wong |
Critical Care Medicine | 2002 |
HSP70 Expression in Skeletal Muscle of Patients with Peripheral Arterial Occlusive Disease
Y Liu, M Lehmann, C Baur, M Storck, L Sunder-Plassmann, JM Steinacker |
European Journal of Vascular and Endovascular Surgery | 2002 |
Blocking HSF1 by Dominant-Negative Mutant to Sensitize Tumor Cells to Hyperthermia
JH Wang, MZ Yao, JF Gu, LY Sun, YF Shen, XY Liu |
Biochemical and Biophysical Research Communications | 2002 |
Glutamine and heat shock protein expression
PE Wischmeyer |
Nutrition | 2002 |
Oral bimoclomol elevates heat shock protein 70 and reduces myocardial infarct size in rats
NL Lubbers, JS Polakowski, CD Wegner, SE Burke, GJ Diaz, KM Daniell, BF Cox |
European Journal of Pharmacology | 2002 |
Mydj2 as a potent partner of hsc70 in mammalian cells
P Bozidis, I Lazaridis, GN Pagoulatos, CE Angelidis |
European Journal of Biochemistry | 2002 |
Advances in Cell Aging and Gerontology
T Fülöp, K Hirokawa, G Dupuis, A Larbi, G Pawelec |
Advances in Cell Aging and Gerontology | 2002 |
Heme oxygenase-1 pathway is involved in delayed protection induced by heat stress against cardiac ischemia–reperfusion injury
R Lu, J Peng, L Xiao, HW Deng, YJ Li |
International Journal of Cardiology | 2002 |
Changes in heat shock protein 70 localization and its content in rabbit aorta at various stages of experimental atherosclerosis
B Geetanjali, S Uma, MP Bansal |
Cardiovascular Pathology | 2002 |
Acute Lung Injury
GD Leikauf, SA McDowell, SC Wesselkamper, WD Hardie, JE Leikauf, TR Korfhagen, DR Prows |
Chest | 2002 |
Exercise-induced elevation of HSP70 is intensity dependent
KJ Milne, EG Noble |
Journal of applied physiology | 2002 |
Association of HSP70 and genotoxic damage in lymphocytes of workers exposed to coke-oven emission
C Xiao, S Chen, J Li, T Hai, Q Lu, E Sun, R Wang, RM Tanguay, T Wu |
Cell Stress and Chaperones | 2002 |
Characterization and functional analysis of a heart-enriched DnaJ/Hsp40 homolog dj4/DjA4
KhalequeAbdul, K Terada, T Gotoh, RahmanHafizur, M Mori |
Cell Stress and Chaperones | 2002 |
Drug Discovery and Evaluation
HG Vogel, WH Vogel, BA Schölkens, J Sandow, G Müller, WF Vogel |
2002 | |
Exercise Improves Postischemic Cardiac Function in Males but Not Females: Consequences of a Novel Sex-Specific Heat Shock Protein 70 Response
Z Paroo, JV Haist, M Karmazyn, EG Noble |
Circulation research | 2002 |
The Sepsis Text
JL Vincent, J Carlet, SM Opal |
2002 | |
Molecular and Cellular Biology of Neuroprotection in the CNS
C Alzheimer |
2002 | |
Small Stress Proteins
AP Arrigo, WE Müller |
2002 | |
Effect of long-term treatment with trandolapril on Hsp72 and Hsp73 induction of the failing heart following myocardial infarction
K Tanonaka, W Toga, H Yoshida, K Furuhama, S Takeo |
British Journal of Pharmacology | 2001 |
Role of nitric oxide synthases in the infarct size-reducing effect conferred by heat stress in isolated rat hearts
C Arnaud, A Laubriet, M Joyeux, D Godin-Ribuot, L Rochette, P Demenge, C Ribuot |
British Journal of Pharmacology | 2001 |
Differential Neuroprotection from Human Heat Shock Protein 70 Overexpression in in Vitro and in Vivo Models of Ischemia and Ischemia-like Conditions
JE Lee, MA Yenari, GH Sun, L Xu, MR Emond, D Cheng, GK Steinberg, RG Giffard |
Experimental Neurology | 2001 |
Induction of stress response proteins and experimental renal ischemia/reperfusion
KJ Kelly, NR Baird, AL Greene |
Kidney International | 2001 |
Functional properties and responses to ischaemia-reperfusion in Langendorff perfused mouse heart
JP Headrick, J Peart, B Hack, A Flood, GP Matherne |
Experimental Physiology | 2001 |
Multilateral in Vivo and in Vitro Protective Effects of the Novel Heat Shock Protein Coinducer, Bimoclomol: Results of Preclinical Studies
PP Nánási, A Jednákovits |
Cardiovascular Drug Reviews | 2001 |
Overexpression of HSP72 After Induction of Experimental Stroke Protects Neurons From Ischemic Damage
B Hoehn, TM Ringer, L Xu, RG Giffard, RM Sapolsky, GK Steinberg, MA Yenari |
Journal of Cerebral Blood Flow & Metabolism | 2001 |
Hyperthermic Pretreatment Decreases Microvascular Protein Leakage and Attenuates Hypotension in Anaphylactic Shock in Rats
SC Chen, TS Lu, HL Lee, SI Lue, RC Yang |
Microvascular Research | 2001 |
Preconditioning Somatothermal Stimulation on Right Seventh Intercostal Nerve Territory Increases Hepatic Heat Shock Protein 70 and Protects the Liver from Ischemia–Reperfusion Injury in Rats
YH Lin, JH Chiu, HH Tung, MT Tsou, WY Lui, CW Wu |
Journal of Surgical Research | 2001 |
Whole Body Hyperthermia Accelerates Atherogenesis in Low-Density Lipoprotein Receptor Deficient Mice
A Afek, G Keren, D Harats, J George |
Experimental and Molecular Pathology | 2001 |
Continuous and pulsed ultrasound do not increase heat shock protein 72 content
M Locke, E Nussbaum |
Ultrasound in Medicine & Biology | 2001 |
Cold Stress Does Not Induce Stress Proteins SP 25 and SP 72 in Rat Skeletal Muscle
M Locke, C Celotti |
Cryobiology | 2001 |
APOPTOSIS IN MYOCARDIAL ISCHEMIA, INFARCTION, AND ALTERED MYOCARDIAL STATES
RR Baliga |
Cardiology Clinics | 2001 |
Gender, Physical Activity, and Aging
D Paterson, L Stathokostas |
Gender, Physical Activity, and Aging | 2001 |
Stress Protein Involvement in Cardioprotection Induced by Hypothermia
R Mestril |
Journal of Molecular and Cellular Cardiology | 2001 |
Mechanisms of cell death in acute myocardial infarction: pathophysiological implications for treatment
C de Zwaan, M J A P Daemen, W Th Hermens |
Netherlands Heart Journal | 2001 |
Heat Shock Proteins and Cardiovascular Pathophysiology
LH Snoeckx, RN Cornelussen, FA van Nieuwenhoven, RS Reneman, GJ van der Vusse |
Physiological reviews | 2001 |
Effects of tobacco smoke and benzo[ a ]pyrene on human endothelial cell and monocyte stress responses
M Vayssier-Taussat, T Camilli, Y Aron, C Meplan, P Hainaut, BS Polla, B Weksler |
American journal of physiology. Heart and circulatory physiology | 2001 |
Overexpression of Bcl-2 attenuates apoptosis and protects against myocardial I/R injury in transgenic mice
Z Chen, CC Chua, YS Ho, RC Hamdy, BH Chua |
American journal of physiology. Heart and circulatory physiology | 2001 |
Strategies of Hypoxia and Anoxia Tolerance in Cardiomyocytes from the Overwintering Common Frog, Rana temporaria
S Currie, RG Boutilier |
Physiological and Biochemical Zoology | 2001 |
Contribution of heat shock proteins to cell protection from complement-mediated lysis
Z Fishelson, I Hochman, LE Greene, E Eisenberg |
International Immunology | 2001 |
Protective effect of heat shock protein 72 on contractile function of perfused failing heart
K Tanonaka, KI Furuhama, H Yoshida, K Kakuta, Y Miyamoto, W Toga, S Takeo |
American journal of physiology. Heart and circulatory physiology | 2001 |
Short-term exercise training can improve myocardial tolerance to I/R without elevation in heat shock proteins
KL Hamilton, SK Powers, T Sugiura, S Kim, S Lennon, N Tumer, JL Mehta |
American journal of physiology. Heart and circulatory physiology | 2001 |
Ischemic-reperfused isolated working mouse hearts: membrane damage and type IIA phospholipase A 2
LJ de Windt, J Willems, TH Roemen, WA Coumans, RS Reneman, GJ van der Vusse, MV Bilsen |
American journal of physiology. Heart and circulatory physiology | 2001 |
Heat pretreatment differentially affects cardiac fatty acid accumulation during ischemia and postischemic reperfusion
RN Cornelussen, GJ van der Vusse, TH Roemen, LH Snoeckx |
American journal of physiology. Heart and circulatory physiology | 2001 |
Role of priming stresses and Hsp70 in protection from ischemia-reperfusion injury in cardiac and skeletal muscle
DA Lepore, KR Knight, RL Anderson, WA Morrison |
Cell Stress and Chaperones | 2001 |
Association of plasma antibodies against the inducible Hsp70 with hypertension and harsh working conditions
T Wu, J Ma, S Chen, Y Sun, C Xiao, Y Gao, R Wang, J Poudrier, M Dargis, RW Currie, RM Tanguay |
Cell Stress and Chaperones | 2001 |
Presence of antibody against the inducible Hsp71 in patients with acute heat-induced illness
T Wu, S Chen, C Xiao, C Wang, Q Pan, Z Wang, M Xie, Z Mao, Y Wu, RM Tanguay |
Cell Stress and Chaperones | 2001 |
Roles of the heat shock transcription factors in regulation of the heat shock response and beyond
L Pirkkala, PÄ Nykänen, L Sistonen |
The FASEB Journal | 2001 |
Role of inducible heat shock protein 70 in radiation-induced cell death
SJ Lee, SA Choi, KH Lee, HY Chung, TH Kim, CK Cho, YS Lee |
Cell Stress and Chaperones | 2001 |
PHARMACOLOGICAL PRECONDITIONING WITH LOW-DOSE CYCLOSPORINE OR FK506 REDUCES SUBSEQUENT ISCHEMIA/REPERFUSION INJURY IN RAT KIDNEY1,2:
CW Yang, HJ Ahn, HJ Han, WY Kim, C Li, MJ Shin, SK Kim, JH Park, YS Kim, IS Moon, BK Bang |
Transplantation | 2001 |
Overexpression of Inducible Heat Shock Protein 70 in COS-1 Cells Fails to Protect From Cytotoxicity of Oxidized LDLs
A Pirillo, GD Norata, T Zanelli, AL Catapano |
Arteriosclerosis, thrombosis, and vascular biology | 2001 |
Molecular Biology of Acute Lung Injury
HR Wong, TP Shanley |
2001 | |
Anaesthesia, Pain, Intensive Care and Emergency Medicine — A.P.I.C.E
A Gullo |
2001 | |
Targeted hsp70.1 Disruption Increases Infarction Volume After Focal Cerebral Ischemia in Mice
SH Lee, M Kim, BW Yoon, YJ Kim, SJ Ma, JK Roh, JS Lee, JS Seo |
Stroke; a journal of cerebral circulation | 2001 |
Thermotherapy for Neoplasia, Inflammation, and Pain
M Kosaka, T Sugahara, KL Schmidt, E Simon |
2001 | |
HSP70-mediated acceleration of translational recovery after stress is independent of ribosomal RNA synthesis
FA Nieuwenhoven, X Martin, VV Heijnen, RN Cornelussen, LH Snoeckx |
European Journal of Cell Biology | 2001 |
The involvement of cytokines in the second window of ischaemic preconditioning
N Yamashita, S Hoshida, K Otsu, N Taniguchi, T Kuzuya, M Hori |
British Journal of Pharmacology | 2000 |
Cytoprotection by electromagnetic field-induced hsp70: A model for clinical application
S Carmody, XL Wu, H Lin, M Blank, H Skopicki, R Goodman |
Journal of Cellular Biochemistry | 2000 |
Hyperthermic induction of the 27-kDa heat shock protein (Hsp27) in neuroglia and neurons of the rat central nervous system
AM Krueger-Naug, DA Hopkins, JN Armstrong, JC Plumier, RW Currie |
The Journal of Comparative Neurology | 2000 |
Impact of hyperthermic preconditioning on postischemic hepatic microcirculatory disturbances in an isolated perfusion model of the rat liver
H Terajima, G Enders, A Thiaener, C Hammer, T Kondo, J Thiery, Y Yamamoto, Y Yamaoka, K Messmer |
Hepatology | 2000 |
Overexpression of CuZnSOD in coronary vascular cells attenuates myocardial ischemia/reperfusion injury
Z Chen, TD Oberley, YS Ho, CC Chua, B Siu, RC Hamdy, CJ Epstein, BH Chua |
Free radical biology & medicine | 2000 |
Mice overexpressing rat heat shock protein 70 are protected against cerebral infarction
S Rajdev, K Hara, Y Kokubo, R Mestril, W Dillmann, PR Weinstein, FR Sharp |
Annals of Neurology | 2000 |
Heat shock transcription factor activation and hsp72 accumulation in aged skeletal muscle
M Locke |
Cell stress & chaperones | 2000 |
Ischemic preconditioning: Lack of delayed protection against skeletal muscle ischemia-reperfusion
DA Lepore, WA Morrison |
Microsurgery | 2000 |
The early response genes c-jun and HSP-70 are induced in regional cardiac stunning in conscious mammals
A Meissner, I Lüss, N Rolf, P Boknik, U Kirchhefer, V Kehm, J Knapp, B Linck, H Lüss, FU Müller, T Weber, W Schmitz, HV Aken, J Neumann |
The Journal of Thoracic and Cardiovascular Surgery | 2000 |
Altered ischemic induction of immediate early gene and heat shock protein 70 mRNAs after preconditioning in rat hearts
Y Nitta-Komatsubara, K Abe, M Aoki, S Isoyama |
Life Sciences | 2000 |
Preconditioning of Human Smooth Muscle Cells via Cyclopentenone Prostaglandins Protects against Toxic Effects of Oxidized Low-Density Lipoprotein
L Hamel, M Kenney, K Clark, L Merkel, C Rojas |
Biochemical and Biophysical Research Communications | 2000 |
Production and Characterization of a Monoclonal Antibody Specific to the Human 70-kDa Heat Shock Protein
DJ Kim, JH Chung, JS Lee, YI Moon, JS Seo, HK Chung |
Hybridoma | 2000 |
Benign focal ischemic preconditioning induces neuronal Hsp70 and prolonged astrogliosis with expression of Hsp27
RW Currie, JA Ellison, RF White, GZ Feuerstein, X Wang, FC Barone |
Brain Research | 2000 |
Adaptive Responses of the Endothelium to Stress
TH Pohlman, JM Harlan |
Journal of Surgical Research | 2000 |
10 kD mitochondrial matrix heat shock protein mRNA is induced following global brain ischemia in the rat
RW Hickey, RL Zhu, HL Alexander, KL Jin, RA Stetler, J Chen, PM Kochanek, SH Graham |
Molecular Brain Research | 2000 |
Inducibility of the 70 kD heat shock protein in peripheral blood monocytes is decreased in human acute respiratory distress syndrome and recovers over time
P Durand, M Bachelet, F Brunet, MJ Richard, JF Dhainaut, J Dall'Ava, BS Polla |
American journal of respiratory and critical care medicine | 2000 |
The heat shock response inhibits NF-kappaB activation, nitric oxide synthase type 2 expression, and macrophage/microglial activation in brain
MT Heneka, A Sharp, T Klockgether, V Gavrilyuk, DL Feinstein |
Journal of Cerebral Blood Flow & Metabolism | 2000 |
Gene therapy for myocardial protection: transfection of donor hearts with heat shock protein 70 gene protects cardiac function against ischemia-reperfusion injury
J Jayakumar, K Suzuki, M Khan, RT Smolenski, A Farrell, N Latif, O Raisky, H Abunasra, IA Sammut, B Murtuza, M Amrani, MH Yacoub |
Circulation | 2000 |
Heat shock factors and the control of the stress response
MG Santoro |
Biochemical Pharmacology | 2000 |
Association of heat shock protein 70 with semen quality in boars
SY Huang, YH Kuo, YP Lee, HL Tsou, EC Lin, CC Ju, WC Lee |
Animal Reproduction Science | 2000 |
Cytoprotective Mechanism of Heat Shock Protein 70 against Hypoxia/Reoxygenation Injury
K Kawana, Y Miyamoto, K Tanonaka, Y Han-no, H Yoshida, M Takahashi, S Takeo |
Journal of Molecular and Cellular Cardiology | 2000 |
Rac1 Regulates Stress-induced, Redox-dependent Heat Shock Factor Activation
M Ozaki, SS Deshpande, P Angkeow, S Suzuki, K Irani |
The Journal of biological chemistry | 2000 |
Glucocorticoid pretreatment protects cardiac function and induces cardiac heat shock protein 72
G Valen, T Kawakami, P Tähepôld, A Dumitrescu, C Löwbeer, J Vaage |
American journal of physiology. Heart and circulatory physiology | 2000 |
Expression of heat shock proteins in turtle and mammal hearts: relationship to anoxia tolerance
J Chang, AA Knowlton, JS Wasser |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 2000 |
Inducible Resistance to Oxidant Stress in the Protozoan Leishmania chagasi
MA Miller, SE McGowan, KR Gantt, M Champion, SL Novick, KA Andersen, CJ Bacchi, N Yarlett, BE Britigan, ME Wilson |
The Journal of biological chemistry | 2000 |
Protection against endotoxemia by HSP70 in rodent cardiomyocytes
SS Lau, TM Griffin, R Mestril |
American journal of physiology. Heart and circulatory physiology | 2000 |
Transgenic overexpression of cardiac A 1 adenosine receptors mimics ischemic preconditioning
RR Morrison, R Jones, AM Byford, AR Stell, J Peart, JP Headrick, GP Matherne |
American journal of physiology. Heart and circulatory physiology | 2000 |
Stress Proteins as Molecular Markers of Neurotoxicity
S Rajdev, FR Sharp |
Toxicologic pathology | 2000 |
A new method of long-term preventive cardioprotection using Lactobacillus
T Oxman, M Shapira, A Diver, R Klein, N Avazov, B Rabinowitz |
American journal of physiology. Heart and circulatory physiology | 2000 |
Cardioprotection by K ATP channels in wild-type hearts and hearts overexpressing A 1 -adenosine receptors
JP Headrick, NS Gauthier, R Morrison, GP Matherne |
American journal of physiology. Heart and circulatory physiology | 2000 |
Suppression of Stress Kinase JNK Is Involved in HSP72-mediated Protection of Myogenic Cells from Transient Energy Deprivation: HSP72 ALLEVIATES THE STRESS-INDUCED INHIBITION OF JNK DEPHOSPHORYLATION
VL Gabai, AB Meriin, JA Yaglom, JY Wei, DD Mosser, MY Sherman |
The Journal of biological chemistry | 2000 |
The myocardial heat shock response following sodium salicylate treatment
M Locke, J Atance |
Cell Stress and Chaperones | 2000 |
The Late Phase of Preconditioning
R Bolli |
Circulation research | 2000 |
Mechanical Stress–Induced Heat Shock Protein 70 Expression in Vascular Smooth Muscle Cells Is Regulated by Rac and Ras Small G Proteins but Not Mitogen-Activated Protein Kinases
Q Xu, G Schett, C Li, Y Hu, G Wick |
Circulation research | 2000 |
Confocal Microscopic Localization of Constitutive and Heat Shock–Induced Proteins HSP70 and HSP27 in the Rat Heart
JP Leger, FM Smith, RW Currie |
Circulation | 2000 |
Apoptosis in Cardiac Biology
H Schunkert, GA Riegger |
2000 | |
Mitochondrial physiology and pathology; concepts of programmed death of organelles, cells and organisms
VP Skulachev |
Molecular Aspects of Medicine | 1999 |
Heat stress response and myocardial protection
M Joyeux, D Godin-Ribuot, DM Yellon, P Demenge, C Ribuot |
Fundamental & Clinical Pharmacology | 1999 |
Heat shock protein 70 (Hsp70) protects postimplantation murine embryos from the embryolethal effects of hyperthermia
PE Mirkes, LM Cornel, KL Wilson, WH Dilmann |
Developmental Dynamics | 1999 |
Heat shock protein 70 overexpression protects LLC-PK1 tubular cells from heat shock but not hypoxia
MA Turman, SL Rosenfeld |
Kidney International | 1999 |
HEAT-SHOCK PROTEINS, MOLECULAR CHAPERONES, AND THE STRESS RESPONSE: Evolutionary and Ecological Physiology
ME Feder, GE Hofmann |
Annual Review of Physiology | 1999 |
Heat stress proteins and myocardial protection: experimental model or potential clinical tool?
CC Gray, M Amrani, MH Yacoub |
The International Journal of Biochemistry & Cell Biology | 1999 |
Heat shock proteins as cellular lifeguards
M Jäättelä |
Annals of Medicine | 1999 |
Inhibition of Myocardial TNF-alpha Production by Heat Shock: A Potential Mechanism of Stress-Induced Cardioprotection against Postischemic Dysfunctiona
X Meng, A Banerjee, L Ao, DR Meldrum, BS Cain, BD Shames, AH Harken |
Annals of the New York Academy of Sciences | 1999 |
Cardiac Adaptation to Ischemia-Reperfusion Injurya
JG Kingma |
Annals of the New York Academy of Sciences | 1999 |
Stress-Response Proteins in Cardiovascular Disease
X Xiao, IJ Benjamin |
The American Journal of Human Genetics | 1999 |
An essential role for NF-κB in the cardioadaptive response to ischemia
EN Morgan, EM Boyle, W Yun, JM Griscavage-Ennis, AL Farr, TG Canty, TH Pohlman, ED Verrier |
The Annals of Thoracic Surgery | 1999 |
Constitutive hsp70 Attenuates Hydrogen Peroxide-Induced Membrane Lipid Peroxidation
CY Su, KY Chong, K Edelstein, S Lille, R Khardori, CC Lai |
Biochemical and Biophysical Research Communications | 1999 |
Aggregation of hsp70 and hsc70in vivois distinct and �temperature-dependent and their chaperone function is �directly related to non-aggregated forms
CE Angelidis, I Lazaridis, GN Pagoulatos |
European Journal of Biochemistry | 1999 |
Liposomal delivery of heat-shock protein 72 into the heart prevents endotoxin-induced myocardial contractile dysfunction
DR Meldrum, X Meng, BD Shames, B Pomerantz, KK Donnahoo, A Banerjee, AH Harken |
Surgery | 1999 |
Analysis ofhsp70gene polymorphism in allergic asthma
Y Aron, M Busson, BS Polla, D Dusser, A Lockhart, E Swierczewski, F Favatier |
Allergy | 1999 |
Role of TNF in Mediating Renal Insufficiency Following Cardiac Surgery: Evidence of a Postbypass Cardiorenal Syndrome
DR Meldrum, KK Donnahoo |
Journal of Surgical Research | 1999 |
Whole body hyperthermia: effects upon canine immune and hemostatic functions
MJ Oglesbee, K Diehl, E Crawford, R Kearns, S Krakowka |
Veterinary Immunology and Immunopathology | 1999 |
The neuroprotective potential of heat shock protein 70 (HSP70)
MA Yenari, RG Giffard, RM Sapolsky, GK Steinberg |
Molecular Medicine Today | 1999 |
Myocardial adaptation to ischaemia – the preconditioning phenomenon
R Carroll, DM Yellon |
International Journal of Cardiology | 1999 |
Induction of 72-kDa heat shock protein does not produce second window of ischemic preconditioning in rat heart
YZ Qian, NL Bernardo, MA Nayeem, J Chelliah, RC Kukreja |
American journal of physiology. Heart and circulatory physiology | 1999 |
Heat shock proteins in cardiosurgery patients
ON Demidov, VV Tyrenko, AS Svistov, YY Komarova, AI Karpishenko, BA Margulis, YL Shevchenko |
European Journal of Cardio-Thoracic Surgery | 1999 |
Differential expression of stress proteins in rat myocardium after free wheel or treadmill run training
EG Noble, A Moraska, RS Mazzeo, DA Roth, MC Olsson, RL Moore, M Fleshner |
Journal of applied physiology | 1999 |
Stress Adaptation, Prophylaxis and Treatment
DK Das |
1999 | |
Reactive Oxygen Species Play an Important Role in the Activation of Heat Shock Factor 1 in Ischemic-Reperfused Heart
J Nishizawa, A Nakai, K Matsuda, M Komeda, T Ban, K Nagata |
Circulation | 1999 |
Stress Proteins
DS Latchman |
1999 | |
Myocardial preconditioning: basic concepts and potential mechanisms
S Okubo, L Xi, N L Bernardo, K Yoshida, R C Kukreja |
Molecular and Cellular Biochemistry | 1999 |
Role of protein kinase C and 72 kDa heat shock protein in ischemic tolerance following heat stress in the rat heart
R C Kukreja, Y Z Qian, S Okubo, E E Flaherty |
Molecular and Cellular Biochemistry | 1999 |
Cardioprotection by Local Heating: Improved Myocardial Salvage After Ischemia and Reperfusion
AG MS, CY MD, GK PhD, JR MD, SR PhD, MS PhD, MM PhD |
The Annals of Thoracic Surgery | 1998 |
Stress–inducible responses and heat shock proteins: New pharmacologic targets for cytoprotection
RI Morimoto, MG Santoro |
Nature Biotechnology | 1998 |
Stress and Work
G Schacke |
Annals of the New York Academy of Sciences | 1998 |
Gene therapy with HSP72 is neuroprotective in rat models of stroke and epilepsy
MA Yenari, SL Fink, GH Sun, LK Chang, MK Patel, DM Kunis, D Onley, DY Ho, RM Sapolsky, GK Steinbrg |
Annals of Neurology | 1998 |
Stress genes protect brain
FR Sharp |
Annals of Neurology | 1998 |
Heat-shock proteins and cardioprotection
IY Malyshev, EV Malysheva |
Bulletin of Experimental Biology and Medicine | 1998 |
Heat shock proteins in inflammation and asthma: Dr Jekyll or Mr Hyde?
Polla, Bachelet, Dall'ava, Vignola |
Clinical & Experimental Allergy | 1998 |
In VivoHeat Shock Protects Rat Myocardial Mitochondria
L Bornman, CM Steinmann, GS Gericke, BS Polla |
Biochemical and Biophysical Research Communications | 1998 |
The Role of Inducible 70-kDa Heat Shock Protein in Cell Cycle Control, Differentiation, and Apoptotic Cell Death of the Human Myeloid Leukemic HL-60 Cells
HJ Kwak, CD Jun, HO Pae, JC Yoo, YC Park, BM Choi, YG Na, RK Park, HT Chung, HY Chung, WY Park, JS Seo |
Cellular Immunology | 1998 |
Oxidant/Antioxidant Imbalance in Skin Aging: Environmental and Adaptative Factors
E Mariethoz, MJ Richard, LL Polla, SE Kreps, J Dal'Ava, BS Polla |
Reviews on Environmental Health | 1998 |
Heat shock protein 72 restores cyclic AMP accumulation after heat shock in N18TG2 cells
H Zensho, A Nishida, M Shimizu, Y Uchitomi, S Yamawaki |
Brain Research | 1998 |
Overexpression of HSP-70 Attenuates Increases in [Ca2+]iand Protects Human Epidermoid A-431 Cells after Chemical Hypoxia
JG Kiang, XZ Ding, DE McClain |
Toxicology and Applied Pharmacology | 1998 |
Induction of the 27-kDa Heat Shock Protein (Hsp27) in the Rat Medulla Oblongata after Vagus Nerve Injury
DA Hopkins, JC Plumier, RW Currie |
Experimental Neurology | 1998 |
Tumor necrosis factor in the heart
DR Meldrum |
American Journal of Physiology - Regulatory, Integrative and Comparative Physiology | 1998 |
Intracellular calcium dynamics in mouse model of myocardial stunning
TG Hampton, I Amende, KE Travers, JP Morgan |
American journal of physiology. Heart and circulatory physiology | 1998 |
Induction of HSP 32 gene in hypoxic cardiomyocytes is attenuated by treatment with N -acetyl- l -cysteine
DR Borger, DA Essig |
American journal of physiology. Heart and circulatory physiology | 1998 |
Specific heat shock proteins protect microtubules during simulated ischemia in cardiac myocytes
WF Bluhm, JL Martin, R Mestril, WH Dillmann |
American journal of physiology. Heart and circulatory physiology | 1998 |
Targeted Disruption of Heat Shock Transcription Factor 1 Abolishes Thermotolerance and Protection against Heat-inducible Apoptosis
DR McMillan, X Xiao, L Shao, K Graves, IJ Benjamin |
The Journal of biological chemistry | 1998 |
Tobacco smoke induces both apoptosis and necrosis in mammalian cells: differential effects of HSP70
M Vayssier, N Banzet, D François, K Bellmann, BS Polla |
American journal of physiology. Lung cellular and molecular physiology | 1998 |
Stress (Heat Shock) Proteins: Molecular Chaperones in Cardiovascular Biology and Disease
IJ Benjamin, DR McMillan |
Circulation research | 1998 |
Thermal Preconditioning Before Rat Arterial Balloon Injury: Limitation of Injury and Sustained Reduction of Intimal Thickening
DG Neschis, SD Safford, PN Raghunath, DJ Langer, ML David, AK Hanna, JE Tomaszewski, K Kariko, ES Barnathan, MA Golden |
Arteriosclerosis, thrombosis, and vascular biology | 1998 |
The Ischemic Heart
S Mochizuki, N Takeda, M Nagano, NS Dhalla |
1998 | |
Cardiovascular Biology of Purines
G Burnstock, JG Dobson, BT Liang, J Linden |
1998 | |
Cardiac Metabolism in Health and Disease
S Abdel-Aleem, JE Lowe |
1998 | |
Myocardial Ischemia and Reperfusion
MV Cohen, RJ Gelpi, JM Downey, J Slezak |
1998 | |
Delayed Preconditioning and Adaptive Cardioprotection
GF Baxter, DM Yellon |
1998 | |
Ischemic preconditioning in isolated perfused mouse heart: reduction in infarct size without improvement of post-ischemic ventricular function
L Xi, M L Hess, R C Kukreja |
Molecular and Cellular Biochemistry | 1998 |
Phospholipase A2-mediated hydrolysis of cardiac phospholipids: the use of molecular and transgenic techniques
L J De Windt, R S Reneman, G J Van der Vusse, M Van Bilsen |
Molecular and Cellular Biochemistry | 1998 |
Heat stress pretreatment mitigates postischemic arachidonic acid accumulation in rat heart
G J van der Vusse, R N Cornelussen, T H Roemen, L H Snoeckx |
Molecular and Cellular Biochemistry | 1998 |
In vivo gene transfection with heat shock protein 70 enhances myocardial tolerance to ischemia-reperfusion injury in rat
K Suzuki, Y Sawa, Y Kaneda, H Ichikawa, R Shirakura, H Matsuda |
Journal of Clinical Investigation | 1997 |
Nitric oxide induces heat-shock protein 70 expression in vascular smooth muscle cells via activation of heat shock factor 1
Q Xu, Y Hu, R Kleindienst, G Wick |
Journal of Clinical Investigation | 1997 |
Adaptive and Maladaptive Mechanisms of Cellular Priming
DR Meldrum, JC Cleveland, EE Moore, DA Partrick, A Banerjee, AH Harken |
Annals of Surgery | 1997 |
Characterization of Human Proximal Tubular Cells after Hypoxic Preconditioning: Constitutive and Hypoxia-Induced Expression of Heat Shock Proteins HSP70 (A, B, and C), HSC70, and HSP90
MA Turman, DA Kahn, SL Rosenfeld, CA Apple, CM Bates |
Biochemical and Molecular Medicine | 1997 |
Heat Shock Response - Pathophysiological Implications
S Leppa, L Sistonen |
Annals of Medicine | 1997 |
Time Course of Delayed Myocardial Protection After Transient Adenosine A1-Receptor Activation in the Rabbit
GF Baxter, DM Yellon |
Journal of Cardiovascular Pharmacology | 1997 |
Bimoclomol: A nontoxic, hydroxylamine derivative with stress protein-inducing activity and cytoprotective effects
L Vígh, PN Literáti, I Horváth, Z Török, G Balogh, A Glatz, E Kovács, I Boros, P Ferdinándy, B Parkas, L Jaszlits, A Jednákovits, L Korányi, B Maresca |
Nature Medicine | 1997 |
On-Pump, Beating-Heart Coronary Artery Operations in High-Risk Patients: An Acceptable Trade-off?
LP Perrault, P Menasché, J Peynet, B Faris, A Bel, T Chaumaray, C Gatecel, B Touchot, G Bloch, JM Moalic |
The Annals of Thoracic Surgery | 1997 |
Induction of myocardial heat shock protein 70 during cardiac surgery
DP Taggart, CJ Bakkenist, SC Biddolph, AK Graham, JO McGee |
The Journal of Pathology | 1997 |
Cortical Application of Potassium Chloride Induces the Low-Molecular Weight Heat Shock Protein (Hsp27) in Astrocytes
JC Plumier, JC David, HA Robertson, RW Currie |
Journal of Cerebral Blood Flow & Metabolism | 1997 |
Adaptive and maladaptive mechanisms of cellular priming
DR Meldrum, JC Cleveland, EE Moore, DA Partrick, A Banerjee, AH Harken |
Annals of Surgery | 1997 |
Transgenic A1 adenosine receptor overexpression increases myocardial resistance to ischemia
GP Matherne, J Linden, AM Byford, NS Gauthier, JP Headrick |
Proceedings of the National Academy of Sciences | 1997 |
Expression of Immediate Early Genes After Cardioplegic Arrest and Reperfusion
HA MD, TC BS, TE BS, SR MD, DE MD, GA MD, HS MD |
The Annals of Thoracic Surgery | 1997 |
Constitutive expression of the 27-kDa heat shock protein (Hsp27) in sensory and motor neurons of the rat nervous system
JC Plumier, DA Hopkins, HA Robertson, RW Currie |
The Journal of Comparative Neurology | 1997 |
Bimoclomol (BRLP-42) Ameliorates Peripheral Neuropathy in Streptozotocin-Induced Diabetic Rats
K Bíró, A Jednákovits, T Kukorelli, E Hegedu″s, L Korányi |
Brain Research Bulletin | 1997 |
Mechanisms of Cardiac Preconditioning: Ten Years after the Discovery of Ischemic Preconditioning
DR Meldrum |
Journal of Surgical Research | 1997 |
Specific Intranucleolar Distribution of Hsp70 during Heat Shock in Polytene Cells
G Morcillo, E Gorab, RM Tanguay, JL Dı́ez |
Experimental Cell Research | 1997 |
Induction of the heat shock response prevents tissue injury during acute inflammation of the rat ileum:
A Stojadinovic, J Kiang, J Goldhill, D Matin, R Smallridge, R Galloway, T Shea-Donohue |
Critical Care Medicine | 1997 |
In vivo exposure to ozone produces an increase in a 72-kDa heat shock protein in guinea pigs
WY Su, T Gordon |
Journal of applied physiology | 1997 |
Differential expression of c-fos, Hsp70 and Hsp27 after photothrombotic injury in the rat brain
JC Plumier, JN Armstrong, NI Wood, JM Babity, TC Hamilton, AJ Hunter, HA Robertson, RW Currie |
Brain research. Molecular brain research | 1997 |
Delayed Coronary Endothelial Protection 24 Hours After Preconditioning: Role of Free Radicals
N Kaeffer, V Richard, C Thuillez |
Circulation | 1997 |
Abundance and Location of the Small Heat Shock Proteins HSP25 and αB-Crystallin in Rat and Human Heart
G Lutsch, R Vetter, U Offhauss, M Wieske, HJ Gröne, R Klemenz, I Schimke, J Stahl, R Benndorf |
Circulation | 1997 |
Blocking the Endogenous Increase in HSP 72 Increases Susceptibility to Hypoxia and Reoxygenation in Isolated Adult Feline Cardiocytes
M Nakano, DL Mann, AA Knowlton |
Circulation | 1997 |
Simultaneous Overexpression of Two Stress Proteins in Rat Cardiomyocytes and Myogenic Cells Confers Protection Against Ischemia-Induced Injury
S Lau, N Patnaik, MR Sayen, R Mestril |
Circulation | 1997 |
Small Heat Shock Proteins and Protection Against Ischemic Injury in Cardiac Myocytes
JL Martin, R Mestril, R Hilal-Dandan, LL Brunton, WH Dillmann |
Circulation | 1997 |
Heat stress increases cardiac HSP72i but fails to reduce myocardial infarct size in rabbits 24 hours later
LJ Saganek, DP Ignasiak, BL Batley, RE Potoczak, G Dodd, KP Gallagher |
Basic Research in Cardiology | 1997 |
Heat Shock Proteins and the Cardiovascular System
AA Knowlton |
1997 | |
Heat Shock Proteins and Cytoprotection
AE Kabakov, VL Gabai |
1997 | |
Environmental Stress, Adaptation and Evolution
R Bijlsma, V Loeschcke |
1997 | |
Reperfusion Injury: Basic Concepts and Protection Strategies
Kukreja, Janin |
Journal of Thrombosis and Thrombolysis | 1997 |
Is "Lethal Reperfusion" an Oxymoron?
Gardner |
Journal of Thrombosis and Thrombolysis | 1997 |
Characterization of cold-induced heat shock protein expression in neonatal rat cardiomyocytes
E Laios, I M Rebeyka, C A Prody |
Molecular and Cellular Biochemistry | 1997 |
Specific induction of the 70-kD heat stress proteins by the tyrosine kinase inhibitor herbimycin-A protects rat neonatal cardiomyocytes. A new pharmacological route to stress protein expression?
SD Morris, DV Cumming, DS Latchman, DM Yellon |
Journal of Clinical Investigation | 1996 |
Stress activated cytokines and the heart
DL Mann |
Cytokine & Growth Factor Reviews | 1996 |
Stress proteins and atherosclerosis
P Roma, AL Catapano |
Atherosclerosis | 1996 |
Delayed protection of the ischemic heart - from pathophysiology to therapeutic applications
V Richard, N Kaeffer, C Thuillez |
Fundamental & Clinical Pharmacology | 1996 |
The effect of tumor necrosis factor-alphaon cardiac structure and function: A tale of two cytokines
DL Mann |
Journal of Cardiac Failure | 1996 |
Heat shock proteins: Applications in health and disease
S Jindal |
Trends in Biotechnology | 1996 |
Windows for HSP 70
LH Snoeckx, R Cornelussen, RS Reneman, GJ Vusse |
Annals of the New York Academy of Sciences | 1996 |
Myocardial Adaptation, Stress Proteins, and the Second Window of Protection
MS Marber, DM Yellon |
Annals of the New York Academy of Sciences | 1996 |
Preservation of the Latissimus Dorsi Muscle During Cardiomyoplasty Surgery
CD Ianuzzo, SE Ianuzzo, M Locke, C Brdlik, WA Anderson, J Gu, RE Klabunde |
Journal of Cardiac Surgery | 1996 |
Protection of the myocardium by ischaemic preconditioning: Mechanisms and therapeutic implications
CG Millar, GF Baxter, C Thiemermann |
Pharmacology & Therapeutics | 1996 |
Tumor Necrosis Factor-?-Induced Cytoprotective Mechanisms in Cardiomyocytes
HS Sharma, D Weisensee, I Löw-Friedrich |
Annals of the New York Academy of Sciences | 1996 |
Cell signaling and heat shock protein expression
JG Kiang, GC Tsokos |
Journal of Biomedical Science | 1996 |
Preconditioning Potentiates Molecular Signaling for Myocardial Adaptation to Ischemia
DK Das, N Maulik, T Yoshida, RM Engelman, YL Zu |
Annals of the New York Academy of Sciences | 1996 |
The Role of Protein Kinase C in Ischemic/Reperfused Preconditioned Isolated Rat Hearts
A Tosaki, N Maulik, DT Engelman, RM Engelman, DK Das |
Journal of Cardiovascular Pharmacology | 1996 |
Myocardial protection after monophosphoryl lipid A: studies of delayed anti-ischaemic properties in rabbit heart
GF Baxter, RW Goodwin, MJ Wright, M Kerac, RJ Heads, DM Yellon |
British Journal of Pharmacology | 1996 |
Mitochondria are selective targets for the protective effects of heat shock against oxidative injury
BS Polla, S Kantengwa, D François, S Salvioli, C Franceschi, C Marsac, A Cossarizza |
Proceedings of the National Academy of Sciences | 1996 |
Cardioprotective effects of 70-kDa heat shock protein in transgenic mice
NB Radford, M Fina, IJ Benjamin, RW Moreadith, KH Graves, P Zhao, S Gavva, A Wiethoff, AD Sherry, CR Malloy, RS Williams |
Proceedings of the National Academy of Sciences | 1996 |
Dual regulation of heat-shock transcription factor (HSF) activation and DNA-binding activity by H2O2: role of thioredoxin
MR Jacquier-Sarlin, BS Polla |
Biochemical Journal | 1996 |
The inducible 70,000molecular weight heat shock protein is expressed in the degenerating dentate hilus and piriform cortex after systemic administration of kainic acid in the rat
JN Armstrong, JC Plumier, HA Robertson, RW Currie |
Neuroscience | 1996 |
Heat shock protein hsp70 overexpression confers resistance against nitric oxide
K Bellmann, M Jäättelä, D Wissing, V Burkart, H Kolb |
FEBS Letters | 1996 |
Methods for studying experimental myocardial ischemic and reperfusion injury
SC Black, IW Rodger |
Journal of Pharmacological and Toxicological Methods | 1996 |
Heat shock proteins: A broader perspective
PL Moseley |
Journal of Laboratory and Clinical Medicine | 1996 |
Expression of the 27,000 mol. wt heat shock protein following kainic acid-induced status epilepticus in the rat
JC Plumier, JN Armstrong, J Landry, JM Babity, HA Robertson, RW Currie |
Neuroscience | 1996 |
Endotoxin induces cardiac HSP70 and resistance to endotoxemic myocardial depression in rats
X Meng, JM Brown, L Ao, SK Nordeen, W Franklin, AH Harken, A Banerjee |
American journal of physiology. Cell physiology | 1996 |
Evidence That a Rapidly Turning Over Protein, Normally Degraded by Proteasomes, Regulates hsp72 Gene Transcription in HepG2 Cells
M Zhou, X Wu, HN Ginsberg |
The Journal of biological chemistry | 1996 |
Stable expression of a human HSP70 gene in a rat myogenic cell line confers protection against endotoxin
SH Chi, R Mestril |
American journal of physiology. Cell physiology | 1996 |
Biochemical Mechanisms in Heart Function
EG Krause, R Vetter |
1996 | |
New Paradigms of Coronary Artery Disease
G Heusch, R Schulz |
1996 | |
Reperfusion Causes Significant Activation of Heat Shock Transcription Factor 1 in Ischemic Rat Heart
J Nishizawa, A Nakai, T Higashi, M Tanabe, S Nomoto, K Matsuda, T Ban, K Nagata |
Circulation | 1996 |
Activation of Heat Shock Transcription Factor 1 in Rat Aorta in Response to High Blood Pressure
Q Xu, TW Fawcett, R Udelsman, NJ Holbrook |
Hypertension | 1996 |
Overexpression of Heat Shock Protein 72 in Transgenic Mice Decreases Infarct Size In Vivo
JJ Hutter, R Mestril, EK Tam, RE Sievers, WH Dillmann, CL Wolfe |
Circulation | 1996 |
Myocardial Ischemia: Mechanisms, Reperfusion, Protection
M Karmazyn |
1996 | |
HSP25 in isolated perfused rat hearts: Localization and response to hyperthermia
B Hoch, G Lutsch, WP Schlegel, J Stahl, G Wallukat, S Bartel, EG Krause, R Benndorf, P Karczewski |
Molecular and Cellular Biochemistry | 1996 |
Monophosphoryl lipid A induces pharmacologic ?preconditioning? in rabbit hearts without concomitant expression of 70-kDa heat shock protein
K Yoshida, MM Maaieh, JB Shipley, M Doloresco, NL Bernardo, YZ Qian, GT Elliott, RC Kukreja |
Molecular and Cellular Biochemistry | 1996 |
Monophosphoryl lipid A induces pharmacologic ?preconditioning? in rabbit hearts without concomitant expression of 70-kDa heat shock protein
K Yoshida, MM Maaieh, JB Shipley, M Doloresco, NL Bernardo, YZ Qian, GT Elliott, RC Kukreja |
Molecular and Cellular Biochemistry | 1996 |
Pharmacological preconditioning of primary rat cardiac myocytes by FK506
D V Cumming, R J Heads, R S Coffin, D M Yellon, D S Latchman |
Basic Research in Cardiology | 1996 |
Delayed myocardial protection following ischaemic preconditioning
G F Baxter, D M Yellon |
Basic Research in Cardiology | 1996 |
Myocardial Self-Preservation: Absence of Heat Shock Factor Activation and Heat Shock Proteins 70 mRNA Accumulation in the Human Heart During Cardiac Surgery
LB McGrath, M Locke |
Journal of Cardiac Surgery | 1995 |
Catalase Inhibition With 3-Amino-1,2,4-Triazole Does Not Abolish Infarct Size Reduction in Heat-Shocked Rats
Y Auyeung, RE Sievers, D Weng, V Barbosa, CL Wolfe |
Circulation | 1995 |
Stress-Inducible Cellular Responses
U Feige, I Yahara, RI Morimoto, BS Polla |
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Leukotrienes
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